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Joseph John Loparo, Ph.D.

TitleAssistant Professor of Biological Chemistry and Molecular Pharmacology
InstitutionHarvard Medical School
DepartmentBiological Chemistry & Molecular Pharmacology
AddressHarvard Medical School
Seeley Mudd Bldg 204A, B C M P
250 Longwood Ave
Boston MA 02115
Phone617/432-5480

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Tanner NA, Tolun G, Loparo JJ, Jergic S, Griffith JD, Dixon NE, van Oijen AM. E. coli DNA replication in the absence of free ß clamps. EMBO J. 2011 May 4; 30(9):1830-40.
    View in: PubMed
  2. Loparo JJ, Kulczyk AW, Richardson CC, van Oijen AM. Simultaneous single-molecule measurements of phage T7 replisome composition and function reveal the mechanism of polymerase exchange. Proc Natl Acad Sci U S A. 2011 Mar 1; 108(9):3584-9.
    View in: PubMed
  3. Kulczyk AW, Tanner NA, Loparo JJ, Richardson CC, van Oijen AM. Direct observation of enzymes replicating DNA using a single-molecule DNA stretching assay. J Vis Exp. 2010; (37).
    View in: PubMed
  4. van Oijen AM, Loparo JJ. Single-molecule studies of the replisome. Annu Rev Biophys. 2010; 39:429-48.
    View in: PubMed
  5. Tanner NA, Loparo JJ, van Oijen AM. Visualizing Single-molecule DNA Replication with Fluorescence Microscopy. J Vis Exp. 2009; (32).
    View in: PubMed
  6. Kochaniak AB, Habuchi S, Loparo JJ, Chang DJ, Cimprich KA, Walter JC, van Oijen AM. Proliferating cell nuclear antigen uses two distinct modes to move along DNA. J Biol Chem. 2009 Jun 26; 284(26):17700-10.
    View in: PubMed
  7. Tanner NA, Loparo JJ, Hamdan SM, Jergic S, Dixon NE, van Oijen AM. Real-time single-molecule observation of rolling-circle DNA replication. Nucleic Acids Res. 2009 Mar; 37(4):e27.
    View in: PubMed
  8. Hamdan SM, Loparo JJ, Takahashi M, Richardson CC, van Oijen AM. Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis. Nature. 2009 Jan 15; 457(7227):336-9.
    View in: PubMed
  9. Loparo JJ, Roberts ST, Tokmakoff A. Multidimensional infrared spectroscopy of water. II. Hydrogen bond switching dynamics. J Chem Phys. 2006 Nov 21; 125(19):194522.
    View in: PubMed
  10. Loparo JJ, Roberts ST, Tokmakoff A. Multidimensional infrared spectroscopy of water. I. Vibrational dynamics in two-dimensional IR line shapes. J Chem Phys. 2006 Nov 21; 125(19):194521.
    View in: PubMed
  11. Roberts ST, Loparo JJ, Tokmakoff A. Characterization of spectral diffusion from two-dimensional line shapes. J Chem Phys. 2006 Aug 28; 125(8):084502.
    View in: PubMed
  12. Eaves JD, Loparo JJ, Fecko CJ, Roberts ST, Tokmakoff A, Geissler PL. Hydrogen bonds in liquid water are broken only fleetingly. Proc Natl Acad Sci U S A. 2005 Sep 13; 102(37):13019-22.
    View in: PubMed
  13. Fecko CJ, Loparo JJ, Roberts ST, Tokmakoff A. Local hydrogen bonding dynamics and collective reorganization in water: ultrafast infrared spectroscopy of HOD/D(2)O. J Chem Phys. 2005 Feb 1; 122(5):54506.
    View in: PubMed
  14. Fecko CJ, Eaves JD, Loparo JJ, Tokmakoff A, Geissler PL. Ultrafast hydrogen-bond dynamics in the infrared spectroscopy of water. Science. 2003 Sep 19; 301(5640):1698-702.
    View in: PubMed
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