 Elaine A. Elion, Ph.D.
| Title | Professor of Biological Chemistry and Molecular Pharmacology |
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| Institution | Harvard Medical School |
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| Department | Biological Chemistry & Molecular Pharmacology |
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| Address | Harvard Medical School
B C M P
240 Longwood Ave
Boston MA 02115
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| Phone | 617/432-3815 |
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| Fax | 617/738-0516 |
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 Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Wang X, Sheff MA, Simpson DM, Elion EA. Ste11p MEKK signals through HOG, mating, calcineurin and PKC pathways to regulate the FKS2 gene. BMC Mol Biol. 2011; 12:51.
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Elion EA, Sahoo R. Analysis of mitogen-activated protein kinase activity in yeast. Methods Mol Biol. 2010; 661:387-99.
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Yu L, Qi M, Sheff MA, Elion EA. Counteractive control of polarized morphogenesis during mating by mitogen-activated protein kinase Fus3 and G1 cyclin-dependent kinase. Mol Biol Cell. 2008 Apr; 19(4):1739-52.
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Elion EA. Detection of protein-protein interactions by coprecipitation. Curr Protoc Protein Sci. 2007 Aug; Chapter 19:Unit 19.4.
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Elion EA, Marina P, Yu L. Constructing recombinant DNA molecules by PCR. Curr Protoc Mol Biol. 2007 Apr; Chapter 3:Unit 3.17.
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Elion EA. Detection of protein-protein interactions by coprecipitation. Curr Protoc Immunol. 2007 Feb; Chapter 8:Unit 8.7.
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Elion EA. Methods for analyzing MAPK cascades. Methods. 2006 Nov; 40(3):207-8.
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Elion EA. Detection of protein-protein interactions by coprecipitation. Curr Protoc Mol Biol. 2006 Nov; Chapter 20:Unit20.5.
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Elion EA. Detection of protein-protein interactions by coprecipitation. Curr Protoc Neurosci. 2006 May; Chapter 5:Unit 5.25.
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Qi M, Elion EA. MAP kinase pathways. J Cell Sci. 2005 Aug 15; 118(Pt 16):3569-72.
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Qi M, Elion EA. Formin-induced actin cables are required for polarized recruitment of the Ste5 scaffold and high level activation of MAPK Fus3. J Cell Sci. 2005 Jul 1; 118(Pt 13):2837-48.
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Elion EA, Qi M, Chen W. Signal transduction. Signaling specificity in yeast. Science. 2005 Feb 4; 307(5710):687-8.
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Wang Y, Chen W, Simpson DM, Elion EA. Cdc24 regulates nuclear shuttling and recruitment of the Ste5 scaffold to a heterotrimeric G protein in Saccharomyces cerevisiae. J Biol Chem. 2005 Apr 1; 280(13):13084-96.
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Flotho A, Simpson DM, Qi M, Elion EA. Localized feedback phosphorylation of Ste5p scaffold by associated MAPK cascade. J Biol Chem. 2004 Nov 5; 279(45):47391-401.
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Andersson J, Simpson DM, Qi M, Wang Y, Elion EA. Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes. EMBO J. 2004 Jul 7; 23(13):2564-76.
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Elion EA, Wang Y. Making protein immunoprecipitates. Methods Mol Biol. 2004; 284:1-14.
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Cherkasova VA, McCully R, Wang Y, Hinnebusch A, Elion EA. A novel functional link between MAP kinase cascades and the Ras/cAMP pathway that regulates survival. Curr Biol. 2003 Jul 15; 13(14):1220-6.
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Wang Y, Elion EA. Nuclear export and plasma membrane recruitment of the Ste5 scaffold are coordinated with oligomerization and association with signal transduction components. Mol Biol Cell. 2003 Jun; 14(6):2543-58.
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Elion EA. How to monitor nuclear shuttling. Methods Enzymol. 2002; 351:607-22.
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Elion EA. The Ste5p scaffold. J Cell Sci. 2001 Nov; 114(Pt 22):3967-78.
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Cherkasova V, Elion EA. far4, far5, and far6 define three genes required for efficient activation of MAPKs Fus3 and Kss1 and accumulation of glycogen. Curr Genet. 2001 Aug; 40(1):13-26.
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Elion EA. Pheromone response, mating and cell biology. Curr Opin Microbiol. 2000 Dec; 3(6):573-81.
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Lee BN, Elion EA. The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components. Proc Natl Acad Sci U S A. 1999 Oct 26; 96(22):12679-84.
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Mahanty SK, Wang Y, Farley FW, Elion EA. Nuclear shuttling of yeast scaffold Ste5 is required for its recruitment to the plasma membrane and activation of the mating MAPK cascade. Cell. 1999 Aug 20; 98(4):501-12.
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Choi KY, Kranz JE, Mahanty SK, Park KS, Elion EA. Characterization of Fus3 localization: active Fus3 localizes in complexes of varying size and specific activity. Mol Biol Cell. 1999 May; 10(5):1553-68.
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Farley FW, Satterberg B, Goldsmith EJ, Elion EA. Relative dependence of different outputs of the Saccharomyces cerevisiae pheromone response pathway on the MAP kinase Fus3p. Genetics. 1999 Apr; 151(4):1425-44.
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Cherkasova V, Lyons DM, Elion EA. Fus3p and Kss1p control G1 arrest in Saccharomyces cerevisiae through a balance of distinct arrest and proliferative functions that operate in parallel with Far1p. Genetics. 1999 Mar; 151(3):989-1004.
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Leza MA, Elion EA. POG1, a novel yeast gene, promotes recovery from pheromone arrest via the G1 cyclin CLN2. Genetics. 1999 Feb; 151(2):531-43.
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Elion EA. Routing MAP kinase cascades. Science. 1998 Sep 11; 281(5383):1625-6.
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Feng Y, Song LY, Kincaid E, Mahanty SK, Elion EA. Functional binding between Gbeta and the LIM domain of Ste5 is required to activate the MEKK Ste11. Curr Biol. 1998 Feb 26; 8(5):267-78.
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Hall JP, Cherkasova V, Elion E, Gustin MC, Winter E. The osmoregulatory pathway represses mating pathway activity in Saccharomyces cerevisiae: isolation of a FUS3 mutant that is insensitive to the repression mechanism. Mol Cell Biol. 1996 Dec; 16(12):6715-23.
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Lyons DM, Mahanty SK, Choi KY, Manandhar M, Elion EA. The SH3-domain protein Bem1 coordinates mitogen-activated protein kinase cascade activation with cell cycle control in Saccharomyces cerevisiae. Mol Cell Biol. 1996 Aug; 16(8):4095-106.
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Elion EA, Trueheart J, Fink GR. Fus2 localizes near the site of cell fusion and is required for both cell fusion and nuclear alignment during zygote formation. J Cell Biol. 1995 Sep; 130(6):1283-96.
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Elion EA. Ste5: a meeting place for MAP kinases and their associates. Trends Cell Biol. 1995 Aug; 5(8):322-7.
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Choi KY, Satterberg B, Lyons DM, Elion EA. Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae. Cell. 1994 Aug 12; 78(3):499-512.
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Brill JA, Elion EA, Fink GR. A role for autophosphorylation revealed by activated alleles of FUS3, the yeast MAP kinase homolog. Mol Biol Cell. 1994 Mar; 5(3):297-312.
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Kranz JE, Satterberg B, Elion EA. The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5. Genes Dev. 1994 Feb 1; 8(3):313-27.
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Elion EA, Satterberg B, Kranz JE. FUS3 phosphorylates multiple components of the mating signal transduction cascade: evidence for STE12 and FAR1. Mol Biol Cell. 1993 May; 4(5):495-510.
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Elion EA, Brill JA, Fink GR. FUS3 represses CLN1 and CLN2 and in concert with KSS1 promotes signal transduction. Proc Natl Acad Sci U S A. 1991 Nov 1; 88(21):9392-6.
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Elion EA, Brill JA, Fink GR. Functional redundancy in the yeast cell cycle: FUS3 and KSS1 have both overlapping and unique functions. Cold Spring Harb Symp Quant Biol. 1991; 56:41-9.
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Elion EA, Grisafi PL, Fink GR. FUS3 encodes a cdc2+/CDC28-related kinase required for the transition from mitosis into conjugation. Cell. 1990 Feb 23; 60(4):649-64.
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Elion EA, Warner JR. An RNA polymerase I enhancer in Saccharomyces cerevisiae. Mol Cell Biol. 1986 Jun; 6(6):2089-97.
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Elion EA, Warner JR. The major promoter element of rRNA transcription in yeast lies 2 kb upstream. Cell. 1984 Dec; 39(3 Pt 2):663-73.
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