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Last Name
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Robert Lawrence Martuza, M.D.

TitleWilliam and Elizabeth Sweet Professor of Neuroscience in the Department of Surgery
InstitutionMassachusetts General Hospital
DepartmentSurgery
AddressFruit St, MGH, Surgery
Boston MA 02114
Phone617/726-8581
Fax617/726-4814

 Mentoring 
 completed student projects
Efficacy of Genetically Engineered ICP6 Mutant Herpes Simplex Viral Vectors for the Treatment of Malignant Glioma
Summer, 04/03/06 - 08/10/06

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Passer BJ, Cheema T, Wu S, Wu CL, Rabkin SD, Martuza RL. Combination of vinblastine and oncolytic herpes simplex virus vector expressing IL-12 therapy increases antitumor and antiangiogenic effects in prostate cancer models. Cancer Gene Ther. 2013 Jan; 20(1):17-24.
    View in: PubMed
  2. Barnard Z, Wakimoto H, Zaupa C, Patel AP, Klehm J, Martuza RL, Rabkin SD, Curry WT. Expression of FMS-like tyrosine kinase 3 ligand by oncolytic herpes simplex virus type I prolongs survival in mice bearing established syngeneic intracranial malignant glioma. Neurosurgery. 2012 Sep; 71(3):741-8; discussion 748.
    View in: PubMed
  3. Ginat DT, Martuza RL. Postoperative imaging of vestibular schwannomas. Neurosurg Focus. 2012 Sep; 33(3):E18.
    View in: PubMed
  4. Tamura K, Wakimoto H, Agarwal AS, Rabkin SD, Bhere D, Martuza RL, Kuroda T, Kasmieh R, Shah K. Multimechanistic tumor targeted oncolytic virus overcomes resistance in brain tumors. Mol Ther. 2013 Jan; 21(1):68-77.
    View in: PubMed
  5. Peterfreund RA, Luman E, Martuza RL. Anesthesia for suboccipital craniotomy in a patient with lymphangioleiomyomatosis: a case report. Case Rep Pulmonol. 2012; 2012:804789.
    View in: PubMed
  6. Sgubin D, Wakimoto H, Kanai R, Rabkin SD, Martuza RL. Oncolytic herpes simplex virus counteracts the hypoxia-induced modulation of glioblastoma stem-like cells. Stem Cells Transl Med. 2012 Apr; 1(4):322-32.
    View in: PubMed
  7. Kanai R, Zaupa C, Sgubin D, Antoszczyk SJ, Martuza RL, Wakimoto H, Rabkin SD. Effect of ?34.5 deletions on oncolytic herpes simplex virus activity in brain tumors. J Virol. 2012 Apr; 86(8):4420-31.
    View in: PubMed
  8. Kanai R, Rabkin SD, Yip S, Sgubin D, Zaupa CM, Hirose Y, Louis DN, Wakimoto H, Martuza RL. Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells. J Natl Cancer Inst. 2012 Jan 4; 104(1):42-55.
    View in: PubMed
  9. Wakimoto H, Mohapatra G, Kanai R, Curry WT, Yip S, Nitta M, Patel AP, Barnard ZR, Stemmer-Rachamimov AO, Louis DN, Martuza RL, Rabkin SD. Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells. Neuro Oncol. 2012 Feb; 14(2):132-44.
    View in: PubMed
  10. Cheema TA, Kanai R, Kim GW, Wakimoto H, Passer B, Rabkin SD, Martuza RL. Enhanced antitumor efficacy of low-dose Etoposide with oncolytic herpes simplex virus in human glioblastoma stem cell xenografts. Clin Cancer Res. 2011 Dec 1; 17(23):7383-93.
    View in: PubMed
  11. Zhang W, Fulci G, Buhrman JS, Stemmer-Rachamimov AO, Chen JW, Wojtkiewicz GR, Weissleder R, Rabkin SD, Martuza RL. Bevacizumab with angiostatin-armed oHSV increases antiangiogenesis and decreases bevacizumab-induced invasion in U87 glioma. Mol Ther. 2012 Jan; 20(1):37-45.
    View in: PubMed
  12. Kleijn A, Chen JW, Buhrman JS, Wojtkiewicz GR, Iwamoto Y, Lamfers ML, Stemmer-Rachamimov AO, Rabkin SD, Weissleder R, Martuza RL, Fulci G. Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging. Clin Cancer Res. 2011 Jul 1; 17(13):4484-93.
    View in: PubMed
  13. Kanai R, Wakimoto H, Martuza RL, Rabkin SD. A novel oncolytic herpes simplex virus that synergizes with phosphoinositide 3-kinase/Akt pathway inhibitors to target glioblastoma stem cells. Clin Cancer Res. 2011 Jun 1; 17(11):3686-96.
    View in: PubMed
  14. Elstner A, Stockhammer F, Nguyen-Dobinsky TN, Nguyen QL, Pilgermann I, Gill A, Guhr A, Zhang T, von Eckardstein K, Picht T, Veelken J, Martuza RL, von Deimling A, Kurtz A. Identification of diagnostic serum protein profiles of glioblastoma patients. J Neurooncol. 2011 Mar; 102(1):71-80.
    View in: PubMed
  15. Passer BJ, Cheema T, Zhou B, Wakimoto H, Zaupa C, Razmjoo M, Sarte J, Wu S, Wu CL, Noah JW, Li Q, Buolamwini JK, Yen Y, Rabkin SD, Martuza RL. Identification of the ENT1 antagonists dipyridamole and dilazep as amplifiers of oncolytic herpes simplex virus-1 replication. Cancer Res. 2010 May 15; 70(10):3890-5.
    View in: PubMed
  16. Castelo-Branco P, Passer BJ, Buhrman JS, Antoszczyk S, Marinelli M, Zaupa C, Rabkin SD, Martuza RL. Oncolytic herpes simplex virus armed with xenogeneic homologue of prostatic acid phosphatase enhances antitumor efficacy in prostate cancer. Gene Ther. 2010 Jun; 17(6):805-10.
    View in: PubMed
  17. Passer BJ, Wu CL, Wu S, Rabkin SD, Martuza RL. Analysis of genetically engineered oncolytic herpes simplex viruses in human prostate cancer organotypic cultures. Gene Ther. 2009 Dec; 16(12):1477-82.
    View in: PubMed
  18. Stankovic KM, Mrugala MM, Martuza RL, Silver M, Betensky RA, Nadol JB, Stemmer-Rachamimov AO. Genetic determinants of hearing loss associated with vestibular schwannomas. Otol Neurotol. 2009 Aug; 30(5):661-7.
    View in: PubMed
  19. Wakimoto H, Kesari S, Farrell CJ, Curry WT, Zaupa C, Aghi M, Kuroda T, Stemmer-Rachamimov A, Shah K, Liu TC, Jeyaretna DS, Debasitis J, Pruszak J, Martuza RL, Rabkin SD. Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors. Cancer Res. 2009 Apr 15; 69(8):3472-81.
    View in: PubMed
  20. Sasportas LS, Kasmieh R, Wakimoto H, Hingtgen S, van de Water JA, Mohapatra G, Figueiredo JL, Martuza RL, Weissleder R, Shah K. Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy. Proc Natl Acad Sci U S A. 2009 Mar 24; 106(12):4822-7.
    View in: PubMed
  21. Passer BJ, Castelo-Branco P, Buhrman JS, Varghese S, Rabkin SD, Martuza RL. Oncolytic herpes simplex virus vectors and taxanes synergize to promote killing of prostate cancer cells. Cancer Gene Ther. 2009 Jul; 16(7):551-60.
    View in: PubMed
  22. Aghi MK, Carter BS, Cosgrove GR, Ojemann RG, Amin-Hanjani S, Martuza RL, Curry WT, Barker FG. Long-term recurrence rates of atypical meningiomas after gross total resection with or without postoperative adjuvant radiation. Neurosurgery. 2009 Jan; 64(1):56-60; discussion 60.
    View in: PubMed
  23. Farrell CJ, Zaupa C, Barnard Z, Maley J, Martuza RL, Rabkin SD, Curry WT. Combination immunotherapy for tumors via sequential intratumoral injections of oncolytic herpes simplex virus 1 and immature dendritic cells. Clin Cancer Res. 2008 Dec 1; 14(23):7711-6.
    View in: PubMed
  24. Farassati F, Pan W, Yamoutpour F, Henke S, Piedra M, Frahm S, Al-Tawil S, Mangrum WI, Parada LF, Rabkin SD, Martuza RL, Kurtz A. Ras signaling influences permissiveness of malignant peripheral nerve sheath tumor cells to oncolytic herpes. Am J Pathol. 2008 Dec; 173(6):1861-72.
    View in: PubMed
  25. Aghi MK, Liu TC, Rabkin S, Martuza RL. Hypoxia enhances the replication of oncolytic herpes simplex virus. Mol Ther. 2009 Jan; 17(1):51-6.
    View in: PubMed
  26. Liu TC, Castelo-Branco P, Rabkin SD, Martuza RL. Trichostatin A and oncolytic HSV combination therapy shows enhanced antitumoral and antiangiogenic effects. Mol Ther. 2008 Jun; 16(6):1041-7.
    View in: PubMed
  27. Sher DJ, Henson JW, Avutu B, Hochberg FH, Batchelor TT, Martuza RL, Barker FG, Loeffler JS, Chakravarti A. The added value of concurrently administered temozolomide versus adjuvant temozolomide alone in newly diagnosed glioblastoma. J Neurooncol. 2008 May; 88(1):43-50.
    View in: PubMed
  28. Liu TC, Wakimoto H, Martuza RL, Rabkin SD. Herpes simplex virus Us3(-) mutant as oncolytic strategy and synergizes with phosphatidylinositol 3-kinase-Akt targeting molecular therapeutics. Clin Cancer Res. 2007 Oct 1; 13(19):5897-902.
    View in: PubMed
  29. Fulci G, Dmitrieva N, Gianni D, Fontana EJ, Pan X, Lu Y, Kaufman CS, Kaur B, Lawler SE, Lee RJ, Marsh CB, Brat DJ, van Rooijen N, Stemmer-Rachamimov AO, Rachamimov AS, Hochberg FH, Weissleder R, Martuza RL, Chiocca EA. Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses. Cancer Res. 2007 Oct 1; 67(19):9398-406.
    View in: PubMed
  30. Varghese S, Rabkin SD, Nielsen GP, MacGarvey U, Liu R, Martuza RL. Systemic therapy of spontaneous prostate cancer in transgenic mice with oncolytic herpes simplex viruses. Cancer Res. 2007 Oct 1; 67(19):9371-9.
    View in: PubMed
  31. Jeyaretna DS, Rabkin SD, Martuza RL. Oncolytic herpes simplex virus therapy for peripheral nerve tumors. Neurosurg Focus. 2007; 22(6):E4.
    View in: PubMed
  32. Prabhakar S, Messerli SM, Stemmer-Rachamimov AO, Liu TC, Rabkin S, Martuza R, Breakefield XO. Treatment of implantable NF2 schwannoma tumor models with oncolytic herpes simplex virus G47Delta. Cancer Gene Ther. 2007 May; 14(5):460-7.
    View in: PubMed
  33. Aghi M, Rabkin SD, Martuza RL. Angiogenic response caused by oncolytic herpes simplex virus-induced reduced thrombospondin expression can be prevented by specific viral mutations or by administering a thrombospondin-derived peptide. Cancer Res. 2007 Jan 15; 67(2):440-4.
    View in: PubMed
  34. Liu TC, Zhang T, Fukuhara H, Kuroda T, Todo T, Canron X, Bikfalvi A, Martuza RL, Kurtz A, Rabkin SD. Dominant-negative fibroblast growth factor receptor expression enhances antitumoral potency of oncolytic herpes simplex virus in neural tumors. Clin Cancer Res. 2006 Nov 15; 12(22):6791-9.
    View in: PubMed
  35. Kuroda T, Rabkin SD, Martuza RL. Effective treatment of tumors with strong beta-catenin/T-cell factor activity by transcriptionally targeted oncolytic herpes simplex virus vector. Cancer Res. 2006 Oct 15; 66(20):10127-35.
    View in: PubMed
  36. Liu TC, Zhang T, Fukuhara H, Kuroda T, Todo T, Martuza RL, Rabkin SD, Kurtz A. Oncolytic HSV armed with platelet factor 4, an antiangiogenic agent, shows enhanced efficacy. Mol Ther. 2006 Dec; 14(6):789-97.
    View in: PubMed
  37. Martuza RL. Vestibular schwannoma. J Neurosurg. 2006 Oct; 105(4):526; discussion 526.
    View in: PubMed
  38. Kuroda T, Martuza RL, Todo T, Rabkin SD. Flip-Flop HSV-BAC: bacterial artificial chromosome based system for rapid generation of recombinant herpes simplex virus vectors using two independent site-specific recombinases. BMC Biotechnol. 2006; 6:40.
    View in: PubMed
  39. Varghese S, Rabkin SD, Nielsen PG, Wang W, Martuza RL. Systemic oncolytic herpes virus therapy of poorly immunogenic prostate cancer metastatic to lung. Clin Cancer Res. 2006 May 1; 12(9):2919-27.
    View in: PubMed
  40. Varghese S, Rabkin SD, Liu R, Nielsen PG, Ipe T, Martuza RL. Enhanced therapeutic efficacy of IL-12, but not GM-CSF, expressing oncolytic herpes simplex virus for transgenic mouse derived prostate cancers. Cancer Gene Ther. 2006 Mar; 13(3):253-65.
    View in: PubMed
  41. Aghi M, Rabkin S, Martuza RL. Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication. J Natl Cancer Inst. 2006 Jan 4; 98(1):38-50.
    View in: PubMed
  42. Messerli SM, Prabhakar S, Tang Y, Mahmood U, Giovannini M, Weissleder R, Bronson R, Martuza R, Rabkin S, Breakefield XO. Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2. Hum Gene Ther. 2006 Jan; 17(1):20-30.
    View in: PubMed
  43. Aghi M, Rabkin S, Martuza RL. Oncolytic herpes simplex virus mutants exhibit enhanced replication in glioma cells evading temozolomide chemotherapy through deoxyribonucleic acid repair. Clin Neurosurg. 2006; 53:65-76.
    View in: PubMed
  44. Fukuhara H, Ino Y, Kuroda T, Martuza RL, Todo T. Triple gene-deleted oncolytic herpes simplex virus vector double-armed with interleukin 18 and soluble B7-1 constructed by bacterial artificial chromosome-mediated system. Cancer Res. 2005 Dec 1; 65(23):10663-8.
    View in: PubMed
  45. Aghi M, Martuza RL. Oncolytic viral therapies - the clinical experience. Oncogene. 2005 Nov 21; 24(52):7802-16.
    View in: PubMed
  46. Fukuhara H, Martuza RL, Rabkin SD, Ito Y, Todo T. Oncolytic herpes simplex virus vector g47delta in combination with androgen ablation for the treatment of human prostate adenocarcinoma. Clin Cancer Res. 2005 Nov 1; 11(21):7886-90.
    View in: PubMed
  47. Chan AW, Black P, Ojemann RG, Barker FG, Kooy HM, Lopes VV, McKenna MJ, Shrieve DC, Martuza RL, Loeffler JS. Stereotactic radiotherapy for vestibular schwannomas: favorable outcome with minimal toxicity. Neurosurgery. 2005 Jul; 57(1):60-70; discussion 60-70.
    View in: PubMed
  48. Mashour GA, Walker EE, Martuza RL. Psychosurgery: past, present, and future. Brain Res Brain Res Rev. 2005 Jun; 48(3):409-19.
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  49. Liu R, Martuza RL, Rabkin SD. Intracarotid delivery of oncolytic HSV vector G47Delta to metastatic breast cancer in the brain. Gene Ther. 2005 Apr; 12(8):647-54.
    View in: PubMed
  50. Mashour GA, Drissel SN, Frahm S, Farassati F, Martuza RL, Mautner VF, Kindler-Röhrborn A, Kurtz A. Differential modulation of malignant peripheral nerve sheath tumor growth by omega-3 and omega-6 fatty acids. Oncogene. 2005 Mar 31; 24(14):2367-74.
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  51. Doolittle ND, Abrey LE, Bleyer WA, Brem S, Davis TP, Dore-Duffy P, Drewes LR, Hall WA, Hoffman JM, Korfel A, Martuza R, Muldoon LL, Peereboom D, Peterson DR, Rabkin SD, Smith Q, Stevens GH, Neuwelt EA. New frontiers in translational research in neuro-oncology and the blood-brain barrier: report of the tenth annual Blood-Brain Barrier Disruption Consortium Meeting. Clin Cancer Res. 2005 Jan 15; 11(2 Pt 1):421-8.
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  52. Mashour GA, Driever PH, Hartmann M, Drissel SN, Zhang T, Scharf B, Felderhoff-Müser U, Sakuma S, Friedrich RE, Martuza RL, Mautner VF, Kurtz A. Circulating growth factor levels are associated with tumorigenesis in neurofibromatosis type 1. Clin Cancer Res. 2004 Sep 1; 10(17):5677-83.
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  53. Kurtz A, Lueth M, Kluwe L, Zhang T, Foster R, Mautner VF, Hartmann M, Tan DJ, Martuza RL, Friedrich RE, Driever PH, Wong LJ. Somatic mitochondrial DNA mutations in neurofibromatosis type 1-associated tumors. Mol Cancer Res. 2004 Aug; 2(8):433-41.
    View in: PubMed
  54. Weber DC, Chan AW, Bussiere MR, Harsh GR, Ancukiewicz M, Barker FG, Thornton AT, Martuza RL, Nadol JB, Chapman PH, Loeffler JS. Proton beam radiosurgery for vestibular schwannoma: tumor control and cranial nerve toxicity. Neurosurgery. 2003 Sep; 53(3):577-86; discussion 586-8.
    View in: PubMed
  55. Nikolic B, Feigenbaum F, Abbara S, Martuza RL, Schellinger D. CT changes of an intracranial granulocytic sarcoma on short-term follow-up. AJR Am J Roentgenol. 2003 Jan; 180(1):78-80.
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  56. Kurtz A, Martuza RL. Antiangiogenesis in neurofibromatosis 1. J Child Neurol. 2002 Aug; 17(8):578-84; discussion 602-4, 646-51.
    View in: PubMed
  57. Jorgensen TJ, Katz S, Wittmack EK, Varghese S, Todo T, Rabkin SD, Martuza RL. Ionizing radiation does not alter the antitumor activity of herpes simplex virus vector G207 in subcutaneous tumor models of human and murine prostate cancer. Neoplasia. 2001 Sep-Oct; 3(5):451-6.
    View in: PubMed
  58. Kirn D, Martuza RL, Zwiebel J. Replication-selective virotherapy for cancer: Biological principles, risk management and future directions. Nat Med. 2001 Jul; 7(7):781-7.
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  59. Varghese S, Newsome JT, Rabkin SD, McGeagh K, Mahoney D, Nielsen P, Todo T, Martuza RL. Preclinical safety evaluation of G207, a replication-competent herpes simplex virus type 1, inoculated intraprostatically in mice and nonhuman primates. Hum Gene Ther. 2001 May 20; 12(8):999-1010.
    View in: PubMed
  60. Todo T, Martuza RL, Rabkin SD, Johnson PA. Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing. Proc Natl Acad Sci U S A. 2001 May 22; 98(11):6396-401.
    View in: PubMed
  61. Mashour GA, Moulding HD, Chahlavi A, Khan GA, Rabkin SD, Martuza RL, Driever PH, Kurtz A, Chalavi A. Therapeutic efficacy of G207 in a novel peripheral nerve sheath tumor model. Exp Neurol. 2001 May; 169(1):64-71.
    View in: PubMed
  62. Wu A, Mazumder A, Martuza RL, Liu X, Thein M, Meehan KR, Rabkin SD. Biological purging of breast cancer cells using an attenuated replication-competent herpes simplex virus in human hematopoietic stem cell transplantation. Cancer Res. 2001 Apr 1; 61(7):3009-15.
    View in: PubMed
  63. Toda M, Martuza RL, Rabkin SD. Combination suicide/cytokine gene therapy as adjuvants to a defective herpes simplex virus-based cancer vaccine. Gene Ther. 2001 Feb; 8(4):332-9.
    View in: PubMed
  64. Mashour GA, Ratner N, Khan GA, Wang HL, Martuza RL, Kurtz A. The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibroma-derived cells. Oncogene. 2001 Jan 4; 20(1):97-105.
    View in: PubMed
  65. Todo T, Martuza RL, Dallman MJ, Rabkin SD. In situ expression of soluble B7-1 in the context of oncolytic herpes simplex virus induces potent antitumor immunity. Cancer Res. 2001 Jan 1; 61(1):153-61.
    View in: PubMed
  66. Todo T, Feigenbaum F, Rabkin SD, Lakeman F, Newsome JT, Johnson PA, Mitchell E, Belliveau D, Ostrove JM, Martuza RL. Viral shedding and biodistribution of G207, a multimutated, conditionally replicating herpes simplex virus type 1, after intracerebral inoculation in aotus. Mol Ther. 2000 Dec; 2(6):588-95.
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  67. Toda M, Martuza RL, Rabkin SD. Tumor growth inhibition by intratumoral inoculation of defective herpes simplex virus vectors expressing granulocyte-macrophage colony-stimulating factor. Mol Ther. 2000 Oct; 2(4):324-9.
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  68. Moulding HD, Martuza RL, Rabkin SD. Clinical mutations in the L1 neural cell adhesion molecule affect cell-surface expression. J Neurosci. 2000 Aug 1; 20(15):5696-702.
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  69. Lim DJ, Rubenstein AE, Evans DG, Jacks T, Seizinger BG, Baser ME, Beebe D, Brackmann DE, Chiocca EA, Fehon RG, Giovannini M, Glazer R, Gusella JF, Gutmann DH, Korf B, Lieberman F, Martuza R, McClatchey AI, Parry DM, Pulst SM, Ramesh V, Ramsey WJ, Ratner N, Rutkowski JL, Ruttledge M, Weinstein DE. Advances in neurofibromatosis 2 (NF2): a workshop report. J Neurogenet. 2000 Jun; 14(2):63-106.
    View in: PubMed
  70. Todo T, Rabkin SD, Martuza RL. Evaluation of ganciclovir-mediated enhancement of the antitumoral effect in oncolytic, multimutated herpes simplex virus type 1 (G207) therapy of brain tumors. Cancer Gene Ther. 2000 Jun; 7(6):939-46.
    View in: PubMed
  71. Markert JM, Medlock MD, Rabkin SD, Gillespie GY, Todo T, Hunter WD, Palmer CA, Feigenbaum F, Tornatore C, Tufaro F, Martuza RL. Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial. Gene Ther. 2000 May; 7(10):867-74.
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  72. Martuza RL. Conditionally replicating herpes vectors for cancer therapy. J Clin Invest. 2000 Apr; 105(7):841-6.
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  73. Sundaresan P, Hunter WD, Martuza RL, Rabkin SD. Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation in mice. J Virol. 2000 Apr; 74(8):3832-41.
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  74. Sandhu FA, Schellinger D, Martuza RL. A vascular sarcoid mass mimicking a convexity meningioma. Neuroradiology. 2000 Mar; 42(3):195-8.
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  75. Sandhu FA, Martuza RL. Craniofacial hemangiopericytoma associated with oncogenic osteomalacia: case report. J Neurooncol. 2000; 46(3):241-7.
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  76. Mashour GA, Martuza RL, Kurtz A. Induction of melanogenic abnormalities in NF1+/- mutant mice by DMBA. J Invest Dermatol. 1999 Dec; 113(6):1133-4.
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  77. Todo T, Rabkin SD, Sundaresan P, Wu A, Meehan KR, Herscowitz HB, Martuza RL. Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus. Hum Gene Ther. 1999 Nov 20; 10(17):2741-55.
    View in: PubMed
  78. Todo T, Rabkin SD, Chahlavi A, Martuza RL. Corticosteroid administration does not affect viral oncolytic activity, but inhibits antitumor immunity in replication-competent herpes simplex virus tumor therapy. Hum Gene Ther. 1999 Nov 20; 10(17):2869-78.
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  79. Chahlavi A, Rabkin S, Todo T, Sundaresan P, Martuza R. Effect of prior exposure to herpes simplex virus 1 on viral vector-mediated tumor therapy in immunocompetent mice. Gene Ther. 1999 Oct; 6(10):1751-8.
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  80. Mashour GA, Wang HL, Cabal-Manzano R, Wellstein A, Martuza RL, Kurtz A. Aberrant cutaneous expression of the angiogenic factor midkine is associated with neurofibromatosis type-1. J Invest Dermatol. 1999 Sep; 113(3):398-402.
    View in: PubMed
  81. Walker JR, McGeagh KG, Sundaresan P, Jorgensen TJ, Rabkin SD, Martuza RL. Local and systemic therapy of human prostate adenocarcinoma with the conditionally replicating herpes simplex virus vector G207. Hum Gene Ther. 1999 Sep 1; 10(13):2237-43.
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  82. Hunter WD, Martuza RL, Feigenbaum F, Todo T, Mineta T, Yazaki T, Toda M, Newsome JT, Platenberg RC, Manz HJ, Rabkin SD. Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation of intracerebral injection in nonhuman primates. J Virol. 1999 Aug; 73(8):6319-26.
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  83. Chahlavi A, Todo T, Martuza RL, Rabkin SD. Replication-competent herpes simplex virus vector G207 and cisplatin combination therapy for head and neck squamous cell carcinoma. Neoplasia. 1999 Jun; 1(2):162-9.
    View in: PubMed
  84. Miyatake SI, Tani S, Feigenbaum F, Sundaresan P, Toda H, Narumi O, Kikuchi H, Hashimoto N, Hangai M, Martuza RL, Rabkin SD. Hepatoma-specific antitumor activity of an albumin enhancer/promoter regulated herpes simplex virus in vivo. Gene Ther. 1999 Apr; 6(4):564-72.
    View in: PubMed
  85. Toda M, Rabkin SD, Kojima H, Martuza RL. Herpes simplex virus as an in situ cancer vaccine for the induction of specific anti-tumor immunity. Hum Gene Ther. 1999 Feb 10; 10(3):385-93.
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  86. New KC, Gale K, Martuza RL, Rabkin SD. Novel synthesis and release of GABA in cerebellar granule cell cultures after infection with defective herpes simplex virus vectors expressing glutamic acid decarboxylase. Brain Res Mol Brain Res. 1998 Oct 30; 61(1-2):121-35.
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  87. Toda M, Rabkin SD, Martuza RL. Treatment of human breast cancer in a brain metastatic model by G207, a replication-competent multimutated herpes simplex virus 1. Hum Gene Ther. 1998 Oct 10; 9(15):2177-85.
    View in: PubMed
  88. Toda M, Martuza RL, Kojima H, Rabkin SD. In situ cancer vaccination: an IL-12 defective vector/replication-competent herpes simplex virus combination induces local and systemic antitumor activity. J Immunol. 1998 May 1; 160(9):4457-64.
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  89. Martuza RL. Act locally, think globally. Nat Med. 1997 Dec; 3(12):1323.
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  90. Miyatake S, Iyer A, Martuza RL, Rabkin SD. Transcriptional targeting of herpes simplex virus for cell-specific replication. J Virol. 1997 Jul; 71(7):5124-32.
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  91. Miyatake S, Martuza RL, Rabkin SD. Defective herpes simplex virus vectors expressing thymidine kinase for the treatment of malignant glioma. Cancer Gene Ther. 1997 Jul-Aug; 4(4):222-8.
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  92. Menon AG, Rutter JL, von Sattel JP, Synder H, Murdoch C, Blumenfeld A, Martuza RL, von Deimling A, Gusella JF, Houseal TW. Frequent loss of chromosome 14 in atypical and malignant meningioma: identification of a putative 'tumor progression' locus. Oncogene. 1997 Feb 6; 14(5):611-6.
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  93. Yazaki T, Martuza RL, Rabkin SD. Expression of L1 in primary astrocytes via a defective herpes simplex virus vector promotes neurite outgrowth and neural cell migration. Brain Res Mol Brain Res. 1996 Dec 31; 43(1-2):311-20.
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  94. Yazaki T, Ahmad S, Chahlavi A, Zylber-Katz E, Dean NM, Rabkin SD, Martuza RL, Glazer RI. Treatment of glioblastoma U-87 by systemic administration of an antisense protein kinase C-alpha phosphorothioate oligodeoxynucleotide. Mol Pharmacol. 1996 Aug; 50(2):236-42.
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  95. Viola JJ, Martuza RL. Gene therapies for glioblastomas. Baillieres Clin Neurol. 1996 Jun; 5(2):413-24.
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  96. Yazaki T, Manz HJ, Rabkin SD, Martuza RL. Treatment of human malignant meningiomas by G207, a replication-competent multimutated herpes simplex virus 1. Cancer Res. 1995 Nov 1; 55(21):4752-6.
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  97. Mineta T, Rabkin SD, Yazaki T, Hunter WD, Martuza RL. Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas. Nat Med. 1995 Sep; 1(9):938-43.
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  98. Baer L, Rauch SL, Ballantine HT, Martuza R, Cosgrove R, Cassem E, Giriunas I, Manzo PA, Dimino C, Jenike MA. Cingulotomy for intractable obsessive-compulsive disorder. Prospective long-term follow-up of 18 patients. Arch Gen Psychiatry. 1995 May; 52(5):384-92.
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  99. Mineta T, Tabuchi K, Martuza RL. [Gene therapy for brain tumors: experimental treatment of malignant brain tumors using recombinant herpes simplex virus type 1 (series 7)]. No Shinkei Geka. 1995 Apr; 23(4):285-92.
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  100. Yazaki T, Takamiya Y, Costello PC, Mineta T, Menon AG, Rabkin SD, Martuza RL. Inhibition of angiogenesis and growth of human non-malignant and malignant meningiomas by TNP-470. J Neurooncol. 1995; 23(1):23-9.
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  101. al-Nabulsi I, Takamiya Y, Voloshin Y, Dritschilo A, Martuza RL, Jorgensen TJ. Expression of thymidine kinase is essential to low dose radiation resistance of rat glioma cells. Cancer Res. 1994 Nov 1; 54(21):5614-7.
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  102. Ahmad S, Mineta T, Martuza RL, Glazer RI. Antisense expression of protein kinase C alpha inhibits the growth and tumorigenicity of human glioblastoma cells. Neurosurgery. 1994 Nov; 35(5):904-8; discussion 908-9.
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  103. Mineta T, Rabkin SD, Martuza RL. Treatment of malignant gliomas using ganciclovir-hypersensitive, ribonucleotide reductase-deficient herpes simplex viral mutant. Cancer Res. 1994 Aug 1; 54(15):3963-6.
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  104. Takamiya Y, Brem H, Ojeifo J, Mineta T, Martuza RL. AGM-1470 inhibits the growth of human glioblastoma cells in vitro and in vivo. Neurosurgery. 1994 May; 34(5):869-75; discussion 875.
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  105. New KC, Martuza RL, Rabkin SD. Defective herpes simplex virus vectors for the study of promoter and gene function in the CNS. Gene Ther. 1994; 1 Suppl 1:S79.
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  106. Baer L, Rauch SL, Jenike MA, Cassem NH, Ballantine HT, Manzo PA, Martuza RL. Cingulotomy in a case of concomitant obsessive-compulsive disorder and Tourette's syndrome. Arch Gen Psychiatry. 1994 Jan; 51(1):73-4.
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  107. Mineta T, Markert JM, Takamiya Y, Coen DM, Rabkin SD, Martuza RL. CNS tumor therapy by attenuated herpes simplex viruses. Gene Ther. 1994; 1 Suppl 1:S78.
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  108. Yu JS, Wei MX, Chiocca EA, Martuza RL, Tepper RI. Treatment of glioma by engineered interleukin 4-secreting cells. Cancer Res. 1993 Jul 1; 53(13):3125-8.
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  109. Takamiya Y, Short MP, Moolten FL, Fleet C, Mineta T, Breakefield XO, Martuza RL. An experimental model of retrovirus gene therapy for malignant brain tumors. J Neurosurg. 1993 Jul; 79(1):104-10.
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  110. Markert JM, Malick A, Coen DM, Martuza RL. Reduction and elimination of encephalitis in an experimental glioma therapy model with attenuated herpes simplex mutants that retain susceptibility to acyclovir. Neurosurgery. 1993 Apr; 32(4):597-603.
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  111. Takamiya Y, Friedlander RM, Brem H, Malick A, Martuza RL. Inhibition of angiogenesis and growth of human nerve-sheath tumors by AGM-1470. J Neurosurg. 1993 Mar; 78(3):470-6.
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  112. Takamiya Y, Short MP, Ezzeddine ZD, Moolten FL, Breakefield XO, Martuza RL. Gene therapy of malignant brain tumors: a rat glioma line bearing the herpes simplex virus type 1-thymidine kinase gene and wild type retrovirus kills other tumor cells. J Neurosci Res. 1992 Nov; 33(3):493-503.
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  113. Nadol JB, Chiong CM, Ojemann RG, McKenna MJ, Martuza RL, Montgomery WW, Levine RA, Ronner SF, Glynn RJ. Preservation of hearing and facial nerve function in resection of acoustic neuroma. Laryngoscope. 1992 Oct; 102(10):1153-8.
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  114. Markert JM, Coen DM, Malick A, Mineta T, Martuza RL. Expanded spectrum of viral therapy in the treatment of nervous system tumors. J Neurosurg. 1992 Oct; 77(4):590-4.
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  115. Lee JK, Sobel RA, Chiocca EA, Kim TS, Martuza RL. Growth of human acoustic neuromas, neurofibromas and schwannomas in the subrenal capsule and sciatic nerve of the nude mouse. J Neurooncol. 1992 Oct; 14(2):101-12.
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  116. Narod SA, Parry DM, Parboosingh J, Lenoir GM, Ruttledge M, Fischer G, Eldridge R, Martuza RL, Frontali M, Haines J, et al. Neurofibromatosis type 2 appears to be a genetically homogeneous disease. Am J Hum Genet. 1992 Sep; 51(3):486-96.
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  117. von Deimling A, Louis DN, von Ammon K, Petersen I, Hoell T, Chung RY, Martuza RL, Schoenfeld DA, Yasargil MG, Wiestler OD, et al. Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme. J Neurosurg. 1992 Aug; 77(2):295-301.
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  118. Poon WS, Schomacker KT, Deutsch TF, Martuza RL. Laser-induced fluorescence: experimental intraoperative delineation of tumor resection margins. J Neurosurg. 1992 Apr; 76(4):679-86.
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  119. McKenna MJ, Halpin C, Ojemann RG, Nadol JB, Montgomery WW, Levine RA, Carlisle E, Martuza R. Long-term hearing results in patients after surgical removal of acoustic tumors with hearing preservation. Am J Otol. 1992 Mar; 13(2):134-6.
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  120. Huang Q, Vonsattel JP, Schaffer PA, Martuza RL, Breakefield XO, DiFiglia M. Introduction of a foreign gene (Escherichia coli lacZ) into rat neostriatal neurons using herpes simplex virus mutants: a light and electron microscopic study. Exp Neurol. 1992 Mar; 115(3):303-16.
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  121. Martuza RL. Molecular neurosurgery for glial and neuronal disorders. Stereotact Funct Neurosurg. 1992; 59(1-4):92-9.
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  122. Flexon PB, Nadol JB, Schuknecht HF, Montgomery WW, Martuza RL. Bilateral acoustic neurofibromatosis (neurofibromatosis 2): a disorder distinct from von Recklinghausen's neurofibromatosis (neurofibromatosis 1). Ann Otol Rhinol Laryngol. 1991 Oct; 100(10):830-4.
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  123. Chung R, Whaley J, Kley N, Anderson K, Louis D, Menon A, Hettlich C, Freiman R, Hedley-Whyte ET, Martuza R, et al. TP53 gene mutations and 17p deletions in human astrocytomas. Genes Chromosomes Cancer. 1991 Sep; 3(5):323-31.
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  124. Ezzeddine ZD, Martuza RL, Platika D, Short MP, Malick A, Choi B, Breakefield XO. Selective killing of glioma cells in culture and in vivo by retrovirus transfer of the herpes simplex virus thymidine kinase gene. New Biol. 1991 Jun; 3(6):608-14.
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  125. Jenike MA, Baer L, Ballantine T, Martuza RL, Tynes S, Giriunas I, Buttolph ML, Cassem NH. Cingulotomy for refractory obsessive-compulsive disorder. A long-term follow-up of 33 patients. Arch Gen Psychiatry. 1991 Jun; 48(6):548-55.
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  126. Martuza RL, Malick A, Markert JM, Ruffner KL, Coen DM. Experimental therapy of human glioma by means of a genetically engineered virus mutant. Science. 1991 May 10; 252(5007):854-6.
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  127. Fontaine B, Sanson M, Delattre O, Menon AG, Rouleau GA, Seizinger BR, Jewell AF, Hanson MP, Aurias A, Martuza RL, et al. Parental origin of chromosome 22 loss in sporadic and NF2 neuromas. Genomics. 1991 May; 10(1):280-3.
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  128. Fontaine B, Hanson MP, VonSattel JP, Martuza RL, Gusella JF. Loss of chromosome 22 alleles in human sporadic spinal schwannomas. Ann Neurol. 1991 Feb; 29(2):183-6.
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  129. Halliday AL, Sobel RA, Martuza RL. Benign spinal nerve sheath tumors: their occurrence sporadically and in neurofibromatosis types 1 and 2. J Neurosurg. 1991 Feb; 74(2):248-53.
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  130. Fontaine B, Rouleau GA, Seizinger BR, Menon AG, Jewell AF, Martuza RL, Gusella JF. Molecular genetics of neurofibromatosis 2 and related tumors (acoustic neuroma and meningioma). Ann N Y Acad Sci. 1991; 615:338-43.
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  131. Steichen JD, Weiss MJ, Elmaleh DR, Martuza RL. Enhanced in vitro uptake and retention of 3H-tetraphenylphosphonium by nervous system tumor cells. J Neurosurg. 1991 Jan; 74(1):116-22.
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  132. Jacoby LB, Hedley-Whyte ET, Pulaski K, Seizinger BR, Martuza RL. Clonal origin of pituitary adenomas. J Neurosurg. 1990 Nov; 73(5):731-5.
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  133. Fontaine B, Rouleau GA, Seizinger B, Jewell AF, Hanson MP, Martuza RL, Gusella JF. Equal parental origin of chromosome 22 losses in human sporadic meningioma: no evidence for genomic imprinting. Am J Hum Genet. 1990 Nov; 47(5):823-7.
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  134. Short MP, Choi BC, Lee JK, Malick A, Breakefield XO, Martuza RL. Gene delivery to glioma cells in rat brain by grafting of a retrovirus packaging cell line. J Neurosci Res. 1990 Nov; 27(3):427-39.
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  135. Jacoby LB, Pulaski K, Rouleau GA, Martuza RL. Clonal analysis of human meningiomas and schwannomas. Cancer Res. 1990 Nov 1; 50(21):6783-6.
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  136. Steichen JD, Stewart RB, Louis DN, Choi BB, Kung R, Martuza RL. A new 1.9-mu wavelength laser for neurosurgery. J Neurosurg. 1990 Oct; 73(4):611-4.
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  137. Lee JK, Choi B, Sobel RA, Chiocca EA, Martuza RL. Inhibition of growth and angiogenesis of human neurofibrosarcoma by heparin and hydrocortisone. J Neurosurg. 1990 Sep; 73(3):429-35.
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  138. Chiocca EA, Choi BB, Cai WZ, DeLuca NA, Schaffer PA, DiFiglia M, Breakefield XO, Martuza RL. Transfer and expression of the lacZ gene in rat brain neurons mediated by herpes simplex virus mutants. New Biol. 1990 Aug; 2(8):739-46.
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  139. Lee JK, Kim TS, Chiocca EA, Medhkour A, Martuza RL. Growth of human schwannomas in the subrenal capsule of the nude mouse. Neurosurgery. 1990 Apr; 26(4):598-605.
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  140. Logan JA, Seizinger BR, Atkins L, Martuza RL. Loss of the Y chromosome in meningiomas. A molecular genetic approach. Cancer Genet Cytogenet. 1990 Mar; 45(1):41-7.
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  141. Rouleau GA, Seizinger BR, Wertelecki W, Haines JL, Superneau DW, Martuza RL, Gusella JF. Flanking markers bracket the neurofibromatosis type 2 (NF2) gene on chromosome 22. Am J Hum Genet. 1990 Feb; 46(2):323-8.
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  142. Louis DN, Hedley-Whyte ET, Martuza RL. Sarcomatous proliferation of the vasculature in a subependymoma: a follow-up study of sarcomatous dedifferentiation. Acta Neuropathol. 1990; 80(5):573-4.
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  143. Martuza RL, Chiocca EA, Jenike MA, Giriunas IE, Ballantine HT. Stereotactic radiofrequency thermal cingulotomy for obsessive compulsive disorder. J Neuropsychiatry Clin Neurosci. 1990; 2(3):331-6.
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  144. Medhkour A, Van Roey M, Sobel RA, Fingert HJ, Lee J, Martuza RL. Implantation of human meningiomas into the subrenal capsule of the nude mouse. A model for studies of tumor growth. J Neurosurg. 1989 Oct; 71(4):545-50.
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  145. el-Azouzi M, Chung RY, Farmer GE, Martuza RL, Black PM, Rouleau GA, Hettlich C, Hedley-Whyte ET, Zervas NT, Panagopoulos K, et al. Loss of distinct regions on the short arm of chromosome 17 associated with tumorigenesis of human astrocytomas. Proc Natl Acad Sci U S A. 1989 Sep; 86(18):7186-90.
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  146. Louis DN, Hedley-Whyte ET, Martuza RL. Sarcomatous proliferation of the vasculature in a subependymoma. Acta Neuropathol. 1989; 78(3):332-5.
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  147. Kostron H, Swartz MR, Martuza RL. Photodynamic therapy is potentiated by Co60 and intratumoral injection of hematoporphyrin derivative. J Neurooncol. 1988 Sep; 6(2):185-91.
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  148. Martuza RL, Eldridge R. Neurofibromatosis 2 (bilateral acoustic neurofibromatosis). N Engl J Med. 1988 Mar 17; 318(11):684-8.
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  149. Martuza RL, Seizinger BR, Jacoby LB, Rouleau GA, Gusella JF. The molecular biology of human glial tumors. Trends Neurosci. 1988 Jan; 11(1):22-7.
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  150. Nadol JB, Levine R, Ojemann RG, Martuza RL, Montgomery WW, de Sandoval PK. Preservation of hearing in surgical removal of acoustic neuromas of the internal auditory canal and cerebellar pontine angle. Laryngoscope. 1987 Nov; 97(11):1287-94.
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  151. Rouleau GA, Wertelecki W, Haines JL, Hobbs WJ, Trofatter JA, Seizinger BR, Martuza RL, Superneau DW, Conneally PM, Gusella JF. Genetic linkage of bilateral acoustic neurofibromatosis to a DNA marker on chromosome 22. Nature. 1987 Sep 17-23; 329(6136):246-8.
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  152. Seizinger BR, de la Monte S, Atkins L, Gusella JF, Martuza RL. Molecular genetic approach to human meningioma: loss of genes on chromosome 22. Proc Natl Acad Sci U S A. 1987 Aug; 84(15):5419-23.
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  153. Seizinger BR, Rouleau G, Ozelius LJ, Lane AH, St George-Hyslop P, Huson S, Gusella JF, Martuza RL. Common pathogenetic mechanism for three tumor types in bilateral acoustic neurofibromatosis. Science. 1987 Apr 17; 236(4799):317-9.
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  154. Seizinger BR, Martuza RL, Rouleau G, Breakefield XO, Gusella JF. Models for inherited susceptibility to cancer in the nervous system: a molecular-genetic approach to neurofibromatosis. Dev Neurosci. 1987; 9(3):144-53.
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  155. Brockes JP, Breakefield XO, Martuza RL. Glial growth factor-like activity in Schwann cell tumors. Ann Neurol. 1986 Sep; 20(3):317-22.
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  156. Steichen JD, Dashner K, Martuza RL. Distribution of hematoporphyrin derivative in canine glioma following intraneoplastic and intraperitoneal injection. J Neurosurg. 1986 Sep; 65(3):364-9.
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  157. Seizinger BR, Martuza RL, Gusella JF. Loss of genes on chromosome 22 in tumorigenesis of human acoustic neuroma. Nature. 1986 Aug 14-20; 322(6080):644-7.
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  158. Bouckoms A, Martuza R, Henderson M. Capgras syndrome with subarachnoid hemorrhage. J Nerv Ment Dis. 1986 Aug; 174(8):484-8.
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  159. Cohen AM, Wood WC, Bamberg M, Martuza R. Cytotoxicity of human brain tumors by hematoporphyrin derivative. J Surg Res. 1986 Jul; 41(1):81-3.
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  160. Kostron H, Bellnier DA, Lin CW, Swartz MR, Martuza RL. Distribution, retention, and phototoxicity of hematoporphyrin derivative in a rat glioma. Intraneoplastic versus intraperitoneal injection. J Neurosurg. 1986 May; 64(5):768-74.
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  161. Kostron H, Swartz MR, Miller DC, Martuza RL. The interaction of hematoporphyrin derivative, light, and ionizing radiation in a rat glioma model. Cancer. 1986 Mar 1; 57(5):964-70.
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  162. Jay JR, MacLaughlin DT, Badger TM, Miller DC, Martuza RL. Hormonal modulation of Schwann cell tumors. I. The effects of estradiol and tamoxifen on methylnitrosourea-induced rat Schwann cell tumors. Ann N Y Acad Sci. 1986; 486:371-82.
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  163. Jacoby LB, Martuza RL. DNA transfection analysis of the tumors of neurofibromatosis. Ann N Y Acad Sci. 1986; 486:333-5.
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  164. Fitzpatrick TB, Martuza RL. Clinical diagnosis of von Recklinghausen's neurofibromatosis. Ann N Y Acad Sci. 1986; 486:383-5.
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  165. Martuza RL, Philippe I, Fitzpatrick TB, Zwaan J, Seki Y, Lederman J. Melanin macroglobules as a cellular marker of neurofibromatosis: a quantitative study. J Invest Dermatol. 1985 Oct; 85(4):347-50.
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  166. Martuza RL, Miller DC, MacLaughlin DT. Estrogen and progestin binding by cytosolic and nuclear fractions of human meningiomas. J Neurosurg. 1985 May; 62(5):750-6.
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  167. Jay JR, MacLaughlin DT, Riley KR, Martuza RL. Modulation of meningioma cell growth by sex steroid hormones in vitro. J Neurosurg. 1985 May; 62(5):757-62.
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  168. Mirimanoff RO, Dosoretz DE, Linggood RM, Ojemann RG, Martuza RL. Meningioma: analysis of recurrence and progression following neurosurgical resection. J Neurosurg. 1985 Jan; 62(1):18-24.
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  169. Granick MS, Martuza RL, Parker SW, Ojemann RG, Montgomery WW. Cerebellopontine angle meningiomas: clinical manifestations and diagnosis. Ann Otol Rhinol Laryngol. 1985 Jan-Feb; 94(1 Pt 1):34-8.
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  170. Martuza RL, Parker SW, Nadol JB, Davis KR, Ojemann RG. Diagnosis of cerebellopontine angle tumors. Clin Neurosurg. 1985; 32:177-213.
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  171. Nakagawa H, Hori Y, Sato S, Fitzpatrick TB, Martuza RL. The nature and origin of the melanin macroglobule. J Invest Dermatol. 1984 Aug; 83(2):134-9.
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  172. Martuza RL. Genetics in neuro-oncology. Clin Neurosurg. 1983; 31:417-40.
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  173. Conner ES, Martuza RL, Heros RC. Seizures due to metrizamide myelography in patients with acute cervical spine injury. Neurosurgery. 1982 Feb; 10(2):266-7.
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  174. Martuza RL, Ojemann RG. Bilateral acoustic neuromas: clinical aspects, pathogenesis, and treatment. Neurosurgery. 1982 Jan; 10(1):1-12.
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  175. Martuza RL, MacLaughlin DT, Ojemann RG. Specific estradiol binding in schwannomas, meningiomas, and neurofibromas. Neurosurgery. 1981 Dec; 9(6):665-71.
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  176. Chapman PH, Martuza RL, Poletti CE, Karchmer AW. Symptomatic spinal epidural lipomatosis associated with Cushing's syndrome. Neurosurgery. 1981 Jun; 8(6):724-7.
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  177. Martuza RL, Ojemann RG, Shillito J, Wepsic JG. Facial pain associated with a middle fossa arachnoid cyst. Neurosurgery. 1981 Jun; 8(6):712-16.
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  178. Martuza RL, Kornblith PL, Liszczak TM. Characteristics of human optic gliomas in tissue culture. J Neurosurg. 1977 Jan; 46(1):78-84.
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  179. Stewart RM, Martuza RL, Baldessarini RJ, Kornblith PL. Glutamate accumulation by human gliomas and meningiomas in tissue culture. Brain Res. 1976 Dec 24; 118(3):441-52.
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  180. Martuza RL, Proffitt MR, Moore MB, Dohan CF. Evaporation as a cause of positional differences in cell plating and growth in microtiter plates. Transplantation. 1976 Mar; 21(3):271-3.
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  181. Phillips JP, Sujatanond M, Martuza RL, Quindlen EA, Wood WC, Kornblith PL, Dohan FC. Cytotoxic antibodies in preoperative glioma patients: a diagnostic assay. Acta Neurochir (Wien). 1976; 35(1-3):43-52.
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  182. Martuza RL, Shamberger RC, Phillips JP, Kornblith PL, Dohan FC, Hochberg FH. A lymphocyte-dependent antibody assay for detection of antibodies to human glioma cells. Surg Forum. 1975; 26:492-4.
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  183. Martuza RL, Black PH, Kornblith PL, Dohan FC. Evidence for presence of a virus in glioblastoma multiforme cells. Surg Forum. 1973; 24:459-61.
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