 Gary Eugene Gilbert, M.D.
| Title | Associate Professor of Medicine |
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| Institution | Brigham and Women's Hospital |
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| Department | Medicine |
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| Address | Boston Va Med Ctr-W Roxbury
1400 V.F.W. Parkway-Med. Serv.
West Roxbury MA 02132
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| Phone | 857/203-5252 |
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| Fax | 857/203-5592 |
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| Title | Deputy Director for Research, Boston VAMC |
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| Institution | Veterans Affairs Boston Healthcare System |
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| Department | Medicine |
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 Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Zhou J, Shi J, Hou J, Cao F, Zhang Y, Rasmussen JT, Heegaard CW, Gilbert GE. Phosphatidylserine exposure and procoagulant activity in acute promyelocytic leukemia. J Thromb Haemost. 2010 Apr; 8(4):773-82.
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Shcherbina A, Cooley J, Lutskiy MI, Benarafa C, Gilbert GE, Remold-O'Donnell E. WASP plays a novel role in regulating platelet responses dependent on alphaIIbbeta3 integrin outside-in signalling. Br J Haematol. 2010 Feb; 148(3):416-27.
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Zhou J, Zheng Y, Shi J, Lu C, Hou J, Yu H, Qiao X, Qi S, Gilbert GE. Daunorubicin induces procoagulant response through phosphatidylserine exposure in red blood cells. Thromb Res. 2010 Feb; 125(2):178-83.
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Meems H, Meijer AB, Cullinan DB, Mertens K, Gilbert GE. Factor VIII C1 domain residues Lys 2092 and Phe 2093 contribute to membrane binding and cofactor activity. Blood. 2009 Oct 29; 114(18):3938-46.
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Waehrens LN, Heegaard CW, Gilbert GE, Rasmussen JT. Bovine lactadherin as a calcium-independent imaging agent of phosphatidylserine expressed on the surface of apoptotic HeLa cells. J Histochem Cytochem. 2009 Oct; 57(10):907-14.
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Zhou J, Liu S, Ma M, Hou J, Yu H, Lu C, Gilbert GE, Shi J. Procoagulant activity and phosphatidylserine of amniotic fluid cells. Thromb Haemost. 2009 May; 101(5):845-51.
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Gilbert GE. Where does von Willebrand factor go? Blood. 2008 Sep 1; 112(5):1549-50.
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Shi J, Pipe SW, Rasmussen JT, Heegaard CW, Gilbert GE. Lactadherin blocks thrombosis and hemostasis in vivo: correlation with platelet phosphatidylserine exposure. J Thromb Haemost. 2008 Jul; 6(7):1167-74.
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Yeung T, Gilbert GE, Shi J, Silvius J, Kapus A, Grinstein S. Membrane phosphatidylserine regulates surface charge and protein localization. Science. 2008 Jan 11; 319(5860):210-3.
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Shao C, Novakovic VA, Head JF, Seaton BA, Gilbert GE. Crystal structure of lactadherin C2 domain at 1.7A resolution with mutational and computational analyses of its membrane-binding motif. J Biol Chem. 2008 Mar 14; 283(11):7230-41.
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Shi J, Shi Y, Waehrens LN, Rasmussen JT, Heegaard CW, Gilbert GE. Lactadherin detects early phosphatidylserine exposure on immortalized leukemia cells undergoing programmed cell death. Cytometry A. 2006 Dec 1; 69(12):1193-201.
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Gilbert GE. Use of microsphere-supported phospholipid membranes for analysis of protein-lipid interactions. Curr Protoc Cytom. 2005 Nov; Chapter 13:Unit13.3.
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Grant MA, Baikeev RF, Gilbert GE, Rigby AC. Lysine 5 and phenylalanine 9 of the factor IX omega-loop interact with phosphatidylserine in a membrane-mimetic environment. Biochemistry. 2004 Dec 14; 43(49):15367-78.
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Shi J, Heegaard CW, Rasmussen JT, Gilbert GE. Lactadherin binds selectively to membranes containing phosphatidyl-L-serine and increased curvature. Biochim Biophys Acta. 2004 Nov 17; 1667(1):82-90.
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Phillips JE, Lord ST, Gilbert GE. Fibrin stimulates platelets to increase factor VIIIa binding site expression. J Thromb Haemost. 2004 Oct; 2(10):1806-15.
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Gary E Gilbert
Jialan Shi
Christian W. Heegaard
Jan T Rasmussen. Method, composition, and kit for detecting phosphatidylserine(PS) on cell membranes. 2004.
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Gary E Gilbert
Jialan Shi. Use of lactadherin as an anticoagulant. 2003.
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Shi J, Gilbert GE. Lactadherin inhibits enzyme complexes of blood coagulation by competing for phospholipid-binding sites. Blood. 2003 Apr 1; 101(7):2628-36.
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Gilbert GE, Kaufman RJ, Arena AA, Miao H, Pipe SW. Four hydrophobic amino acids of the factor VIII C2 domain are constituents of both the membrane-binding and von Willebrand factor-binding motifs. J Biol Chem. 2002 Feb 22; 277(8):6374-81.
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Shi J, Gilbert GE, Kokubo Y, Ohashi T. Role of the liver in regulating numbers of circulating neutrophils. Blood. 2001 Aug 15; 98(4):1226-30.
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Blostein MD, Rigby AC, Furie BC, Furie B, Gilbert GE. Amphipathic helices support function of blood coagulation factor IXa. Biochemistry. 2000 Oct 3; 39(39):12000-6.
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Bendetowicz AV, Wise RJ, Gilbert GE. Collagen-bound von Willebrand factor has reduced affinity for factor VIII. J Biol Chem. 1999 Apr 30; 274(18):12300-7.
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Gilbert GE, Arena AA. Unsaturated phospholipid acyl chains are required to constitute membrane binding sites for factor VIII. Biochemistry. 1998 Sep 29; 37(39):13526-35.
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Bendetowicz AV, Morris JA, Wise RJ, Gilbert GE, Kaufman RJ. Binding of factor VIII to von willebrand factor is enabled by cleavage of the von Willebrand factor propeptide and enhanced by formation of disulfide-linked multimers. Blood. 1998 Jul 15; 92(2):529-38.
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Veeraraghavan S, Baleja JD, Gilbert GE. Structure and topography of the membrane-binding C2 domain of factor VIII in the presence of dodecylphosphocholine micelles. Biochem J. 1998 Jun 1; 332 ( Pt 2):549-55.
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Gilbert GE, Arena AA. Partial activation of the factor VIIIa-factor IXa enzyme complex by dihexanoic phosphatidylserine at submicellar concentrations. Biochemistry. 1997 Sep 2; 36(35):10768-76.
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Saenko EL, Shima M, Gilbert GE, Scandella D. Slowed release of thrombin-cleaved factor VIII from von Willebrand factor by a monoclonal and a human antibody is a novel mechanism for factor VIII inhibition. J Biol Chem. 1996 Nov 1; 271(44):27424-31.
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Gilbert GE, Arena AA. Activation of the factor VIIIa-factor IXa enzyme complex of blood coagulation by membranes containing phosphatidyl-L-serine. J Biol Chem. 1996 May 10; 271(19):11120-5.
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Scandella D, Gilbert GE, Shima M, Nakai H, Eagleson C, Felch M, Prescott R, Rajalakshmi KJ, Hoyer LW, Saenko E. Some factor VIII inhibitor antibodies recognize a common epitope corresponding to C2 domain amino acids 2248 through 2312, which overlap a phospholipid-binding site. Blood. 1995 Sep 1; 86(5):1811-9.
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Gilbert GE, Arena AA. Phosphatidylethanolamine induces high affinity binding sites for factor VIII on membranes containing phosphatidyl-L-serine. J Biol Chem. 1995 Aug 4; 270(31):18500-5.
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Gilbert GE, Baleja JD. Membrane-binding peptide from the C2 domain of factor VIII forms an amphipathic structure as determined by NMR spectroscopy. Biochemistry. 1995 Mar 7; 34(9):3022-31.
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Gilbert GE, Drinkwater D. Specific membrane binding of factor VIII is mediated by O-phospho-L-serine, a moiety of phosphatidylserine. Biochemistry. 1993 Sep 21; 32(37):9577-85.
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Bardelle C, Furie B, Furie BC, Gilbert GE. Membrane binding kinetics of factor VIII indicate a complex binding process. J Biol Chem. 1993 Apr 25; 268(12):8815-24.
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Gilbert GE, Drinkwater D, Barter S, Clouse SB. Specificity of phosphatidylserine-containing membrane binding sites for factor VIII. Studies with model membranes supported by glass microspheres (lipospheres). J Biol Chem. 1992 Aug 5; 267(22):15861-8.
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Gilbert GE, Sims PJ, Wiedmer T, Furie B, Furie BC, Shattil SJ. Platelet-derived microparticles express high affinity receptors for factor VIII. J Biol Chem. 1991 Sep 15; 266(26):17261-8.
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Larsen E, Palabrica T, Sajer S, Gilbert GE, Wagner DD, Furie BC, Furie B. PADGEM-dependent adhesion of platelets to monocytes and neutrophils is mediated by a lineage-specific carbohydrate, LNF III (CD15). Cell. 1990 Nov 2; 63(3):467-74.
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Gilbert GE, Furie BC, Furie B. Binding of human factor VIII to phospholipid vesicles. J Biol Chem. 1990 Jan 15; 265(2):815-22.
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Larsen E, Celi A, Gilbert GE, Furie BC, Erban JK, Bonfanti R, Wagner DD, Furie B. PADGEM protein: a receptor that mediates the interaction of activated platelets with neutrophils and monocytes. Cell. 1989 Oct 20; 59(2):305-12.
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