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Last Name
Institution

Eric Allen Macklin, PH.D.

TitleInstructor in Medicine
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
MGH Biostatistics, Ste 560
50 Staniford Street
Boston MA 02114
Phone617/724-9828
Fax617/724-9878

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Denninger J, Jacquart J, Miller K, Radossi A, Haime V, Macklin E, Gilburd D, Oliver MN, Mehta D, Yeung A, Fricchione G, Benson H. The effectiveness of a community-based mind body group intervention for depression & anxiety: a pilot study. J Altern Complement Med. 2014 May; 20(5):A55.
    View in: PubMed
  2. Wills AM, Hubbard J, Macklin EA, Glass J, Tandan R, Simpson EP, Brooks B, Gelinas D, Mitsumoto H, Mozaffar T, Hanes GP, Ladha SS, Heiman-Patterson T, Katz J, Lou JS, Mahoney K, Grasso D, Lawson R, Yu H, Cudkowicz M. Hypercaloric enteral nutrition in patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled phase 2 trial. Lancet. 2014 Jun 14; 383(9934):2065-72.
    View in: PubMed
  3. Schwarzschild MA, Ascherio A, Beal MF, Cudkowicz ME, Curhan GC, Hare JM, Hooper DC, Kieburtz KD, Macklin EA, Oakes D, Rudolph A, Shoulson I, Tennis MK, Espay AJ, Gartner M, Hung A, Bwala G, Lenehan R, Encarnacion E, Ainslie M, Castillo R, Togasaki D, Barles G, Friedman JH, Niles L, Carter JH, Murray M, Goetz CG, Jaglin J, Ahmed A, Russell DS, Cotto C, Goudreau JL, Russell D, Parashos SA, Ede P, Saint-Hilaire MH, Thomas CA, James R, Stacy MA, Johnson J, Gauger L, Antonelle de Marcaida J, Thurlow S, Isaacson SH, Carvajal L, Rao J, Cook M, Hope-Porche C, McClurg L, Grasso DL, Logan R, Orme C, Ross T, Brocht AF, Constantinescu R, Sharma S, Venuto C, Weber J, Eaton K. Inosine to increase serum and cerebrospinal fluid urate in Parkinson disease: a randomized clinical trial. JAMA Neurol. 2014 Feb 1; 71(2):141-50.
    View in: PubMed
  4. Stefanescu A, Macklin EA, Lin E, Dudzinski DM, Johnson J, Kennedy KF, Jacoby D, Defaria Yeh D, Lewis GD, Yeh RW, Liberthson R, Lui G, Bhatt AB. Usefulness of the Seattle heart failure model to identify adults with congenital heart disease at high risk of poor outcome. Am J Cardiol. 2014 Mar 1; 113(5):865-70.
    View in: PubMed
  5. Atassi N, Yerramilli-Rao P, Szymonifka J, Yu H, Kearney M, Grasso D, Deng J, Levine-Weinberg M, Shapiro J, Lee A, Joseph L, Macklin EA, Cudkowicz ME. Analysis of start-up, retention, and adherence in ALS clinical trials. Neurology. 2013 Oct 8; 81(15):1350-5.
    View in: PubMed
  6. Goff DC, McEvoy JP, Citrome L, Mech AW, Bustillo JR, Gil R, Buckley P, Manschreck TC, Achtyes ED, Macklin EA. High-dose oral ziprasidone versus conventional dosing in schizophrenia patients with residual symptoms: the ZEBRAS study. J Clin Psychopharmacol. 2013 Aug; 33(4):485-90.
    View in: PubMed
  7. Corben AD, Abi-Raad R, Popa I, Teo CH, Macklin EA, Koerner FC, Taghian AG, Brachtel EF. Pathologic response and long-term follow-up in breast cancer patients treated with neoadjuvant chemotherapy: a comparison between classifications and their practical application. Arch Pathol Lab Med. 2013 Aug; 137(8):1074-82.
    View in: PubMed
  8. Alert MD, Rastegar S, Foret M, Slipp L, Jacquart J, Macklin E, Baim M, Fricchione G, Benson H, Denninger J, Yeung A. The effectiveness of a comprehensive mind body weight loss intervention for overweight and obese adults: a pilot study. Complement Ther Med. 2013 Aug; 21(4):286-93.
    View in: PubMed
  9. Roffman JL, Lamberti JS, Achtyes E, Macklin EA, Galendez GC, Raeke LH, Silverstein NJ, Smoller JW, Hill M, Goff DC. Randomized multicenter investigation of folate plus vitamin B12 supplementation in schizophrenia. JAMA Psychiatry. 2013 May; 70(5):481-9.
    View in: PubMed
  10. Miller TM, Pestronk A, David W, Rothstein J, Simpson E, Appel SH, Andres PL, Mahoney K, Allred P, Alexander K, Ostrow LW, Schoenfeld D, Macklin EA, Norris DA, Manousakis G, Crisp M, Smith R, Bennett CF, Bishop KM, Cudkowicz ME. An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study. Lancet Neurol. 2013 May; 12(5):435-42.
    View in: PubMed
  11. Macklin EA, Blacker D, Hyman BT, Betensky RA. Improved design of prodromal Alzheimer's disease trials through cohort enrichment and surrogate endpoints. J Alzheimers Dis. 2013 Jan 1; 36(3):475-86.
    View in: PubMed
  12. Hill M, Crumlish N, Clarke M, Whitty P, Owens E, Renwick L, Browne S, Macklin EA, Kinsella A, Larkin C, Waddington JL, O'Callaghan E. Prospective relationship of duration of untreated psychosis to psychopathology and functional outcome over 12 years. Schizophr Res. 2012 Nov; 141(2-3):215-21.
    View in: PubMed
  13. Göbel A, Macklin EA, Winkler S, Betensky RA, Klein C, Lohmann K, Simon DK. Genetic risk factors in Parkinson's disease: single gene effects and interactions of genotypes. J Neurol. 2012 Nov; 259(11):2503-5.
    View in: PubMed
  14. Deipolyi AR, Wu O, Macklin EA, Schaefer PW, Schwamm LH, Gilberto Gonzalez R, Copen WA. Reliability of cerebral blood volume maps as a substitute for diffusion-weighted imaging in acute ischemic stroke. J Magn Reson Imaging. 2012 Nov; 36(5):1083-7.
    View in: PubMed
  15. Pulliam SJ, Weinstein DF, Malhotra A, Macklin EA, Berkowitz LR. Baseline sleep dysfunction among matriculating interns. J Grad Med Educ. 2012 Jun; 4(2):202-8.
    View in: PubMed
  16. Lau T, Weinstein M, Wakamatsu M, Macklin EA, Pulliam S. Low back pain does not improve with surgical treatment of pelvic organ prolapse. Int Urogynecol J. 2013 Jan; 24(1):147-53.
    View in: PubMed
  17. Roffman JL, Brohawn DG, Nitenson AZ, Macklin EA, Smoller JW, Goff DC. Genetic variation throughout the folate metabolic pathway influences negative symptom severity in schizophrenia. Schizophr Bull. 2013 Mar; 39(2):330-8.
    View in: PubMed
  18. Tinsley A, Macklin EA, Korzenik JR, Sands BE. Validation of the functional assessment of chronic illness therapy-fatigue (FACIT-F) in patients with inflammatory bowel disease. Aliment Pharmacol Ther. 2011 Dec; 34(11-12):1328-36.
    View in: PubMed
  19. Viswanathan AN, Macklin EA, Berkowitz R, Matulonis U. The importance of chemotherapy and radiation in uterine papillary serous carcinoma. Gynecol Oncol. 2011 Dec; 123(3):542-7.
    View in: PubMed
  20. Gottlieb JD, Cather C, Shanahan M, Creedon T, Macklin EA, Goff DC. D-cycloserine facilitation of cognitive behavioral therapy for delusions in schizophrenia. Schizophr Res. 2011 Sep; 131(1-3):69-74.
    View in: PubMed
  21. Henderson DC, Freudenreich O, Borba CP, Wang X, Copeland PM, Macklin E, Fan X, Cather C, Goff DC. Effects of modafinil on weight, glucose and lipid metabolism in clozapine-treated patients with schizophrenia. Schizophr Res. 2011 Aug; 130(1-3):53-6.
    View in: PubMed
  22. Berin I, McLellan ST, Macklin EA, Toth TL, Wright DL. Frozen-thawed embryo transfer cycles: clinical outcomes of single and double blastocyst transfers. J Assist Reprod Genet. 2011 Jul; 28(7):575-81.
    View in: PubMed
  23. Hill M, Shannahan K, Jasinski S, Macklin EA, Raeke L, Roffman JL, Goff DC. Folate supplementation in schizophrenia: a possible role for MTHFR genotype. Schizophr Res. 2011 Apr; 127(1-3):41-5.
    View in: PubMed
  24. Holloway CL, Macklin EA, Cormack RA, Viswanathan AN. Should the organs at risk be contoured in vaginal cuff brachytherapy? Brachytherapy. 2011 Jul-Aug; 10(4):313-7.
    View in: PubMed
  25. Young GS, Macklin EA, Setayesh K, Lawson JD, Wen PY, Norden AD, Drappatz J, Kesari S. Longitudinal MRI evidence for decreased survival among periventricular glioblastoma. J Neurooncol. 2011 Aug; 104(1):261-9.
    View in: PubMed
  26. Sabatini ME, Wolkovich AM, Macklin EA, Wright DL, Souter I, Toth TL. Pronuclear embryo cryopreservation experience: outcomes for reducing the risk of ovarian hyperstimulation syndrome and for fertility preservation in cancer patients. J Assist Reprod Genet. 2011 Mar; 28(3):279-84.
    View in: PubMed
  27. Ajijola OA, Macklin EA, Moore SA, McCarty D, Bischoff KE, Heist EK, Picard M, Ruskin JN, Dec GW, Singh JP. Inpatient vs. elective outpatient cardiac resynchronization therapy device implantation and long-term clinical outcome. Europace. 2010 Dec; 12(12):1745-9.
    View in: PubMed
  28. Phan CM, Macklin EA, Bredella MA, Dadrich M, Flechsig P, Yoo AJ, Hirsch JA, Gupta R. Trabecular structure analysis using C-arm CT: comparison with MDCT and flat-panel volume CT. Skeletal Radiol. 2011 Aug; 40(8):1065-72.
    View in: PubMed
  29. Leeman BA, Macklin EA, Schomer DL, O'Connor MG. Remote memory deficits in epilepsy and the role of failed consolidation. Epilepsy Behav. 2010 Aug; 18(4):498-9.
    View in: PubMed
  30. Healy BC, Ikle D, Macklin EA, Cutter G. Optimal design and analysis of phase I/II clinical trials in multiple sclerosis with gadolinium-enhanced lesions as the endpoint. Mult Scler. 2010 Jul; 16(7):840-7.
    View in: PubMed
  31. Wang ML, Macklin EA, Tracy E, Nadel H, Catlin EA. Updated parental viewpoints on male neonatal circumcision in the United States. Clin Pediatr (Phila). 2010 Feb; 49(2):130-6.
    View in: PubMed
  32. Conboy LA, Macklin E, Kelley J, Kokkotou E, Lembo A, Kaptchuk T. Which patients improve: characteristics increasing sensitivity to a supportive patient-practitioner relationship. Soc Sci Med. 2010 Feb; 70(3):479-84.
    View in: PubMed
  33. Mitha AP, Reichardt B, Grasruck M, Macklin E, Bartling S, Leidecker C, Schmidt B, Flohr T, Brady TJ, Ogilvy CS, Gupta R. Dynamic imaging of a model of intracranial saccular aneurysms using ultra-high-resolution flat-panel volumetric computed tomography. Laboratory investigation. J Neurosurg. 2009 Nov; 111(5):947-57.
    View in: PubMed
  34. Freudenreich O, Henderson DC, Macklin EA, Evins AE, Fan X, Cather C, Walsh JP, Goff DC. Modafinil for clozapine-treated schizophrenia patients: a double-blind, placebo-controlled pilot trial. J Clin Psychiatry. 2009 Dec; 70(12):1674-80.
    View in: PubMed
  35. Leeman BA, Macklin EA, Schomer DL, O'Connor MG. Transient News Events Test: feasibility in assessment of post-temporal lobectomy remote memory deficits. Epilepsy Behav. 2009 Sep; 16(1):113-9.
    View in: PubMed
  36. Vogiatzi MG, Macklin EA, Trachtenberg FL, Fung EB, Cheung AM, Vichinsky E, Olivieri N, Kirby M, Kwiatkowski JL, Cunningham M, Holm IA, Fleisher M, Grady RW, Peterson CM, Giardina PJ. Differences in the prevalence of growth, endocrine and vitamin D abnormalities among the various thalassaemia syndromes in North America. Br J Haematol. 2009 Sep; 146(5):546-56.
    View in: PubMed
  37. Vogiatzi MG, Macklin EA, Fung EB, Cheung AM, Vichinsky E, Olivieri N, Kirby M, Kwiatkowski JL, Cunningham M, Holm IA, Lane J, Schneider R, Fleisher M, Grady RW, Peterson CC, Giardina PJ. Bone disease in thalassemia: a frequent and still unresolved problem. J Bone Miner Res. 2009 Mar; 24(3):543-57.
    View in: PubMed
  38. Kesari S, Schiff D, Drappatz J, LaFrankie D, Doherty L, Macklin EA, Muzikansky A, Santagata S, Ligon KL, Norden AD, Ciampa A, Bradshaw J, Levy B, Radakovic G, Ramakrishna N, Black PM, Wen PY. Phase II study of protracted daily temozolomide for low-grade gliomas in adults. Clin Cancer Res. 2009 Jan 1; 15(1):330-7.
    View in: PubMed
  39. Huang S, Dunkley-Thompson J, Tang Y, Macklin EA, Steel-Duncan J, Singh-Minott I, Ryland EG, Smikle M, Walker BD, Christie CD, Feeney ME. Deficiency of HIV-Gag-specific T cells in early childhood correlates with poor viral containment. J Immunol. 2008 Dec 1; 181(11):8103-11.
    View in: PubMed
  40. Field JJ, Macklin EA, Yan Y, Strunk RC, DeBaun MR. Sibling history of asthma is a risk factor for pain in children with sickle cell anemia. Am J Hematol. 2008 Nov; 83(11):855-7.
    View in: PubMed
  41. Walter PB, Macklin EA, Porter J, Evans P, Kwiatkowski JL, Neufeld EJ, Coates T, Giardina PJ, Vichinsky E, Olivieri N, Alberti D, Holland J, Harmatz P. Inflammation and oxidant-stress in beta-thalassemia patients treated with iron chelators deferasirox (ICL670) or deferoxamine: an ancillary study of the Novartis CICL670A0107 trial. Haematologica. 2008 Jun; 93(6):817-25.
    View in: PubMed
  42. Valaskatgis P, Macklin EA, Schachter SC, Wayne PM. Possible effects of acupuncture on atrial fibrillation and post-herpetic neuralgia--a case report. Acupunct Med. 2008 Mar; 26(1):51-6.
    View in: PubMed
  43. Boyd JH, Macklin EA, Strunk RC, DeBaun MR. Asthma is associated with increased mortality in individuals with sickle cell anemia. Haematologica. 2007 Aug; 92(8):1115-8.
    View in: PubMed
  44. Schaechter JD, Connell BD, Stason WB, Kaptchuk TJ, Krebs DE, Macklin EA, Schnyer RN, Stein J, Scarborough DM, Parker SW, McGibbon CA, Wayne PM. Correlated change in upper limb function and motor cortex activation after verum and sham acupuncture in patients with chronic stroke. J Altern Complement Med. 2007 Jun; 13(5):527-32.
    View in: PubMed
  45. Macklin EA, Wayne PM, Kalish LA, Valaskatgis P, Thompson J, Pian-Smith MC, Zhang Q, Stevens S, Goertz C, Prineas RJ, Buczynski B, Zusman RM. Stop Hypertension with the Acupuncture Research Program (SHARP): results of a randomized, controlled clinical trial. Hypertension. 2006 Nov; 48(5):838-45.
    View in: PubMed
  46. Rogers CA, Wayne PM, Macklin EA, Muilenberg ML, Wagner CJ, Epstein PR, Bazzaz FA. Interaction of the onset of spring and elevated atmospheric CO2 on ragweed (Ambrosia artemisiifolia L.) pollen production. Environ Health Perspect. 2006 Jun; 114(6):865-9.
    View in: PubMed
  47. Boyd JH, Macklin EA, Strunk RC, DeBaun MR. Asthma is associated with acute chest syndrome and pain in children with sickle cell anemia. Blood. 2006 Nov 1; 108(9):2923-7.
    View in: PubMed
  48. Wayne PM, Krebs DE, Macklin EA, Schnyer R, Kaptchuk TJ, Parker SW, Scarborough DM, McGibbon CA, Schaechter JD, Stein J, Stason WB. Acupuncture for upper-extremity rehabilitation in chronic stroke: a randomized sham-controlled study. Arch Phys Med Rehabil. 2005 Dec; 86(12):2248-55.
    View in: PubMed
  49. Vogiatzi MG, Macklin EA, Fung EB, Vichinsky E, Olivieri N, Kwiatkowski J, Cohen A, Neufeld E, Giardina PJ. Prevalence of fractures among the Thalassemia syndromes in North America. Bone. 2006 Apr; 38(4):571-5.
    View in: PubMed
  50. Vichinsky EP, MacKlin EA, Waye JS, Lorey F, Olivieri NF. Changes in the epidemiology of thalassemia in North America: a new minority disease. Pediatrics. 2005 Dec; 116(6):e818-25.
    View in: PubMed
  51. Lukas SE, Penetar D, Berko J, Vicens L, Palmer C, Mallya G, Macklin EA, Lee DY. An extract of the Chinese herbal root kudzu reduces alcohol drinking by heavy drinkers in a naturalistic setting. Alcohol Clin Exp Res. 2005 May; 29(5):756-62.
    View in: PubMed
  52. Hopper JW, Karlsgodt KH, Adler CM, Macklin EA, Lukas SE, Elman I. Effects of acute cortisol and cocaine administration on attention, recall and recognition task performance in individuals with cocaine dependence. Hum Psychopharmacol. 2004 Oct; 19(7):511-6.
    View in: PubMed
  53. Cunningham MJ, Macklin EA, Neufeld EJ, Cohen AR. Complications of beta-thalassemia major in North America. Blood. 2004 Jul 1; 104(1):34-9.
    View in: PubMed
  54. Kalish LA, Buczynski B, Connell P, Gemmel A, Goertz C, Macklin EA, Pian-Smith M, Stevens S, Thompson J, Valaskatgis P, Wayne PM, Zusman RM. Stop Hypertension with the Acupuncture Research Program (SHARP): clinical trial design and screening results. Control Clin Trials. 2004 Feb; 25(1):76-103.
    View in: PubMed
  55. Pegelow CH, Macklin EA, Moser FG, Wang WC, Bello JA, Miller ST, Vichinsky EP, DeBaun MR, Guarini L, Zimmerman RA, Younkin DP, Gallagher DM, Kinney TR. Longitudinal changes in brain magnetic resonance imaging findings in children with sickle cell disease. Blood. 2002 Apr 15; 99(8):3014-8.
    View in: PubMed
  56. Miller ST, Macklin EA, Pegelow CH, Kinney TR, Sleeper LA, Bello JA, DeWitt LD, Gallagher DM, Guarini L, Moser FG, Ohene-Frempong K, Sanchez N, Vichinsky EP, Wang WC, Wethers DL, Younkin DP, Zimmerman RA, DeBaun MR. Silent infarction as a risk factor for overt stroke in children with sickle cell anemia: a report from the Cooperative Study of Sickle Cell Disease. J Pediatr. 2001 Sep; 139(3):385-90.
    View in: PubMed
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