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Last Name
Institution

Brian Dale Snyder, PH.D., M.D.

TitleAssociate Professor of Orthopedic Surgery
InstitutionChildren's Hospital Boston
DepartmentOrthopedic Surgery
AddressChildrens Hospital
Orthopedic Surgery
300 Longwood Ave
Boston MA 02115
Phone617/355-8361
Fax617/730-0459

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Luu AN, Anez-Bustillos L, Aran S, Araiza Arroyo FJ, Entezari V, Rosso C, Snyder BD, Nazarian A. Microstructural, densitometric and metabolic variations in bones from rats with normal or altered skeletal States. PLoS One. 2013; 8(12):e82709.
    View in: PubMed
  2. Anez-Bustillos L, Derikx LC, Verdonschot N, Calderon N, Zurakowski D, Snyder BD, Nazarian A, Tanck E. Finite element analysis and CT-based structural rigidity analysis to assess failure load in bones with simulated lytic defects. Bone. 2014 Jan; 58:160-7.
    View in: PubMed
  3. Rennick JA, Nazarian A, Entezari V, Kimbaris J, Tseng A, Masoudi A, Nayeb-Hashemi H, Vaziri A, Snyder BD. Finite element analysis and computed tomography based structural rigidity analysis of rat tibia with simulated lytic defects. J Biomech. 2013 Oct 18; 46(15):2701-9.
    View in: PubMed
  4. Lakin BA, Grasso DJ, Stewart RC, Freedman JD, Snyder BD, Grinstaff MW. Contrast enhanced CT attenuation correlates with the GAG content of bovine meniscus. J Orthop Res. 2013 Nov; 31(11):1765-71.
    View in: PubMed
  5. Corona J, Miller DJ, Downs J, Akbarnia BA, Betz RR, Blakemore LC, Campbell RM, Flynn JM, Johnston CE, McCarthy RE, Roye DP, Skaggs DL, Smith JT, Snyder BD, Sponseller PD, Sturm PF, Thompson GH, Yazici M, Vitale MG. Evaluating the extent of clinical uncertainty among treatment options for patients with early-onset scoliosis. J Bone Joint Surg Am. 2013 May 15; 95(10):e671-10.
    View in: PubMed
  6. Stewart RC, Bansal PN, Entezari V, Lusic H, Nazarian RM, Snyder BD, Grinstaff MW. Contrast-enhanced CT with a High-Affinity Cationic Contrast Agent for Imaging ex Vivo Bovine, Intact ex Vivo Rabbit, and in Vivo Rabbit Cartilage. Radiology. 2013 Jan; 266(1):141-50.
    View in: PubMed
  7. McElroy MJ, Sponseller PD, Dattilo JR, Thompson GH, Akbarnia BA, Shah SA, Snyder BD. Growing rods for the treatment of scoliosis in children with cerebral palsy: a critical assessment. Spine (Phila Pa 1976). 2012 Nov 15; 37(24):E1504-10.
    View in: PubMed
  8. Lakin BA, Grasso DJ, Shah SS, Stewart RC, Bansal PN, Freedman JD, Grinstaff MW, Snyder BD. Cationic agent contrast-enhanced computed tomography imaging of cartilage correlates with the compressive modulus and coefficient of friction. Osteoarthritis Cartilage. 2013 Jan; 21(1):60-8.
    View in: PubMed
  9. Gordon LB, Kleinman ME, Miller DT, Neuberg DS, Giobbie-Hurder A, Gerhard-Herman M, Smoot LB, Gordon CM, Cleveland R, Snyder BD, Fligor B, Bishop WR, Statkevich P, Regen A, Sonis A, Riley S, Ploski C, Correia A, Quinn N, Ullrich NJ, Nazarian A, Liang MG, Huh SY, Schwartzman A, Kieran MW. Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A. 2012 Oct 9; 109(41):16666-71.
    View in: PubMed
  10. Cleveland RH, Gordon LB, Kleinman ME, Miller DT, Gordon CM, Snyder BD, Nazarian A, Giobbie-Hurder A, Neuberg D, Kieran MW. A prospective study of radiographic manifestations in Hutchinson-Gilford progeria syndrome. Pediatr Radiol. 2012 Sep; 42(9):1089-98.
    View in: PubMed
  11. Ali MR, Snyder B, El-Sayed MA. Synthesis and optical properties of small Au nanorods using a seedless growth technique. Langmuir. 2012 Jun 26; 28(25):9807-15.
    View in: PubMed
  12. Mahan ST, Osborn E, Bae DS, Waters PM, Kasser JR, Kocher MS, Snyder BD, Hresko MT. Changing practice patterns: the impact of a randomized clinical trial on surgeons preference for treatment of type 3 supracondylar humerus fractures. J Pediatr Orthop. 2012 Jun; 32(4):340-5.
    View in: PubMed
  13. Smith MD, Baldassarri S, Anez-Bustillos L, Tseng A, Entezari V, Zurakowski D, Snyder BD, Nazarian A. Assessment of axial bone rigidity in rats with metabolic diseases using CT-based structural rigidity analysis. Bone Joint Res. 2012 Feb; 1(2):13-9.
    View in: PubMed
  14. Entezari V, Vartanians V, Zurakowski D, Patel N, Fajardo RJ, Müller R, Snyder BD, Nazarian A. Further improvements on the factors affecting bone mineral density measured by quantitative micro-computed tomography. Bone. 2012 Mar; 50(3):611-8.
    View in: PubMed
  15. Nazarian A, Araiza Arroyo FJ, Rosso C, Aran S, Snyder BD. Tensile properties of rat femoral bone as functions of bone volume fraction, apparent density and volumetric bone mineral density. J Biomech. 2011 Sep 2; 44(13):2482-8.
    View in: PubMed
  16. Gordon CM, Gordon LB, Snyder BD, Nazarian A, Quinn N, Huh S, Giobbie-Hurder A, Neuberg D, Cleveland R, Kleinman M, Miller DT, Kieran MW. Hutchinson-Gilford progeria is a skeletal dysplasia. J Bone Miner Res. 2011 Jul; 26(7):1670-9.
    View in: PubMed
  17. Olson JC, Kurek KC, Mehta HP, Warman ML, Snyder BD. Expansion thoracoplasty affects lung growth and morphology in a rabbit model: a pilot study. Clin Orthop Relat Res. 2011 May; 469(5):1375-82.
    View in: PubMed
  18. Bansal PN, Stewart RC, Entezari V, Snyder BD, Grinstaff MW. Contrast agent electrostatic attraction rather than repulsion to glycosaminoglycans affords a greater contrast uptake ratio and improved quantitative CT imaging in cartilage. Osteoarthritis Cartilage. 2011 Aug; 19(8):970-6.
    View in: PubMed
  19. Entezari V, Basto PA, Vartanians V, Zurakowski D, Snyder BD, Nazarian A. Non-invasive assessment of failure torque in rat bones with simulated lytic lesions using computed tomography based structural rigidity analysis. J Biomech. 2011 Feb 3; 44(3):552-6.
    View in: PubMed
  20. Bansal PN, Joshi NS, Entezari V, Malone BC, Stewart RC, Snyder BD, Grinstaff MW. Cationic contrast agents improve quantification of glycosaminoglycan (GAG) content by contrast enhanced CT imaging of cartilage. J Orthop Res. 2011 May; 29(5):704-9.
    View in: PubMed
  21. Khoo X, O'Toole GA, Nair SA, Snyder BD, Kenan DJ, Grinstaff MW. Staphylococcus aureus resistance on titanium coated with multivalent PEGylated-peptides. Biomaterials. 2010 Dec; 31(35):9285-92.
    View in: PubMed
  22. Leong NL, Anderson ME, Gebhardt MC, Snyder BD. Computed tomography-based structural analysis for predicting fracture risk in children with benign skeletal neoplasms: comparison of specificity with that of plain radiographs. J Bone Joint Surg Am. 2010 Aug 4; 92(9):1827-33.
    View in: PubMed
  23. Pierre MA, Zurakowski D, Nazarian A, Hauser-Kara DA, Snyder BD. Assessment of the bilateral asymmetry of human femurs based on physical, densitometric, and structural rigidity characteristics. J Biomech. 2010 Aug 10; 43(11):2228-36.
    View in: PubMed
  24. Dodwell ER, Latorre JG, Parisini E, Zwettler E, Chandra D, Mulpuri K, Snyder B. NSAID exposure and risk of nonunion: a meta-analysis of case-control and cohort studies. Calcif Tissue Int. 2010 Sep; 87(3):193-202.
    View in: PubMed
  25. Jarrett DY, Oliveira AM, Zou KH, Snyder BD, Kleinman PK. Axial oblique CT to assess femoral anteversion. AJR Am J Roentgenol. 2010 May; 194(5):1230-3.
    View in: PubMed
  26. Nazarian A, Pezzella L, Tseng A, Baldassarri S, Zurakowski D, Evans CH, Snyder BD. Application of structural rigidity analysis to assess fidelity of healed fractures in rat femurs with critical defects. Calcif Tissue Int. 2010 May; 86(5):397-403.
    View in: PubMed
  27. Cao H, Nazarian A, Ackerman JL, Snyder BD, Rosenberg AE, Nazarian RM, Hrovat MI, Dai G, Mintzopoulos D, Wu Y. Quantitative (31)P NMR spectroscopy and (1)H MRI measurements of bone mineral and matrix density differentiate metabolic bone diseases in rat models. Bone. 2010 Jun; 46(6):1582-90.
    View in: PubMed
  28. Mehta HP, Snyder BD, Baldassarri SR, Hayward MJ, Giuffrida MJ, Entezari V, Jackson AC. Expansion thoracoplasty improves respiratory function in a rabbit model of postnatal pulmonary hypoplasia: a pilot study. Spine (Phila Pa 1976). 2010 Jan 15; 35(2):153-61.
    View in: PubMed
  29. Cory E, Nazarian A, Entezari V, Vartanians V, Müller R, Snyder BD. Compressive axial mechanical properties of rat bone as functions of bone volume fraction, apparent density and micro-ct based mineral density. J Biomech. 2010 Mar 22; 43(5):953-60.
    View in: PubMed
  30. Nazarian A, Meier D, Müller R, Snyder BD. Functional dependence of cancellous bone shear properties on trabecular microstructure evaluated using time-lapsed micro-computed tomographic imaging and torsion testing. J Orthop Res. 2009 Dec; 27(12):1667-74.
    View in: PubMed
  31. Bansal PN, Joshi NS, Entezari V, Grinstaff MW, Snyder BD. Contrast enhanced computed tomography can predict the glycosaminoglycan content and biomechanical properties of articular cartilage. Osteoarthritis Cartilage. 2010 Feb; 18(2):184-91.
    View in: PubMed
  32. Joshi NS, Bansal PN, Stewart RC, Snyder BD, Grinstaff MW. Effect of contrast agent charge on visualization of articular cartilage using computed tomography: exploiting electrostatic interactions for improved sensitivity. J Am Chem Soc. 2009 Sep 23; 131(37):13234-5.
    View in: PubMed
  33. Khoo X, Hamilton P, O'Toole GA, Snyder BD, Kenan DJ, Grinstaff MW. Directed assembly of PEGylated-peptide coatings for infection-resistant titanium metal. J Am Chem Soc. 2009 Aug 12; 131(31):10992-7.
    View in: PubMed
  34. Sun E, Alkalay R, Vader D, Snyder BD. Preventing distal pullout of posterior spine instrumentation in thoracic hyperkyphosis: a biomechanical analysis. J Spinal Disord Tech. 2009 Jun; 22(4):270-7.
    View in: PubMed
  35. Nazarian A, Entezari V, Vartanians V, Müller R, Snyder BD. An improved method to assess torsional properties of rodent long bones. J Biomech. 2009 Aug 7; 42(11):1720-5.
    View in: PubMed
  36. Steines D, Liew SW, Arnaud C, Vargas-Voracek R, Nazarian A, Müller R, Snyder B, Hess P, Lang P. Radiographic trabecular 2D and 3D parameters of proximal femoral bone cores correlate with each other and with yield stress. Osteoporos Int. 2009 Nov; 20(11):1929-38.
    View in: PubMed
  37. Nazarian A, Hermannsson BJ, Muller J, Zurakowski D, Snyder BD. Effects of tissue preservation on murine bone mechanical properties. J Biomech. 2009 Jan 5; 42(1):82-6.
    View in: PubMed
  38. Nazarian A, Bauernschmitt M, Eberle C, Meier D, Müller R, Snyder BD. Design and validation of a testing system to assess torsional cancellous bone failure in conjunction with time-lapsed micro-computed tomographic imaging. J Biomech. 2008 Dec 5; 41(16):3496-501.
    View in: PubMed
  39. Nazarian A, von Stechow D, Zurakowski D, Müller R, Snyder BD. Bone volume fraction explains the variation in strength and stiffness of cancellous bone affected by metastatic cancer and osteoporosis. Calcif Tissue Int. 2008 Dec; 83(6):368-79.
    View in: PubMed
  40. Degoricija L, Bansal PN, Söntjens SH, Joshi NS, Takahashi M, Snyder B, Grinstaff MW. Hydrogels for osteochondral repair based on photocrosslinkable carbamate dendrimers. Biomacromolecules. 2008 Oct; 9(10):2863-72.
    View in: PubMed
  41. Fajardo RJ, Cory E, Patel ND, Nazarian A, Laib A, Manoharan RK, Schmitz JE, DeSilva JM, MacLatchy LM, Snyder BD, Bouxsein ML. Specimen size and porosity can introduce error into microCT-based tissue mineral density measurements. Bone. 2009 Jan; 44(1):176-84.
    View in: PubMed
  42. Nazarian A, Cory E, Müller R, Snyder BD. Shortcomings of DXA to assess changes in bone tissue density and microstructure induced by metabolic bone diseases in rat models. Osteoporos Int. 2009 Jan; 20(1):123-32.
    View in: PubMed
  43. Nazarian A, Snyder BD, Zurakowski D, Müller R. Quantitative micro-computed tomography: a non-invasive method to assess equivalent bone mineral density. Bone. 2008 Aug; 43(2):302-11.
    View in: PubMed
  44. Banerji A, Clark S, Blanda M, LoVecchio F, Snyder B, Camargo CA. Multicenter study of patients with angiotensin-converting enzyme inhibitor-induced angioedema who present to the emergency department. Ann Allergy Asthma Immunol. 2008 Apr; 100(4):327-32.
    View in: PubMed
  45. Kocher MS, Kasser JR, Waters PM, Bae D, Snyder BD, Hresko MT, Hedequist D, Karlin L, Kim YJ, Murray MM, Millis MB, Emans JB, Dichtel L, Matheney T, Lee BM. Lateral entry compared with medial and lateral entry pin fixation for completely displaced supracondylar humeral fractures in children. A randomized clinical trial. J Bone Joint Surg Am. 2007 Apr; 89(4):706-12.
    View in: PubMed
  46. Wu Y, Dai G, Ackerman JL, Hrovat MI, Glimcher MJ, Snyder BD, Nazarian A, Chesler DA. Water- and fat-suppressed proton projection MRI (WASPI) of rat femur bone. Magn Reson Med. 2007 Mar; 57(3):554-67.
    View in: PubMed
  47. Nazarian A, Muller J, Zurakowski D, Müller R, Snyder BD. Densitometric, morphometric and mechanical distributions in the human proximal femur. J Biomech. 2007; 40(11):2573-9.
    View in: PubMed
  48. Murray MM, Spindler KP, Abreu E, Muller JA, Nedder A, Kelly M, Frino J, Zurakowski D, Valenza M, Snyder BD, Connolly SA. Collagen-platelet rich plasma hydrogel enhances primary repair of the porcine anterior cruciate ligament. J Orthop Res. 2007 Jan; 25(1):81-91.
    View in: PubMed
  49. Sawamura C, Takahashi M, McCarthy KJ, Shen Z, Fukai N, Rodriguez EK, Snyder BD. Effect of in ovo immobilization on development of chick hind-limb articular cartilage: an evaluation using micro-MRI measurement of delayed gadolinium uptake. Magn Reson Med. 2006 Dec; 56(6):1235-41.
    View in: PubMed
  50. Mehta HP, Snyder BD, Callender NN, Bellardine CL, Jackson AC. The reciprocal relationship between thoracic and spinal deformity and its effect on pulmonary function in a rabbit model: a pilot study. Spine (Phila Pa 1976). 2006 Nov 1; 31(23):2654-64.
    View in: PubMed
  51. Nazarian A, Stauber M, Zurakowski D, Snyder BD, Müller R. The interaction of microstructure and volume fraction in predicting failure in cancellous bone. Bone. 2006 Dec; 39(6):1196-202.
    View in: PubMed
  52. Karageorgiou V, Tomkins M, Fajardo R, Meinel L, Snyder B, Wade K, Chen J, Vunjak-Novakovic G, Kaplan DL. Porous silk fibroin 3-D scaffolds for delivery of bone morphogenetic protein-2 in vitro and in vivo. J Biomed Mater Res A. 2006 Aug; 78(2):324-34.
    View in: PubMed
  53. Diab M, Daluvoy S, Snyder BD, Kasser JR. Osteotomy does not improve early outcome after slipped capital femoral epiphysis. J Pediatr Orthop B. 2006 Mar; 15(2):87-92.
    View in: PubMed
  54. Snyder BD, Hauser-Kara DA, Hipp JA, Zurakowski D, Hecht AC, Gebhardt MC. Predicting fracture through benign skeletal lesions with quantitative computed tomography. J Bone Joint Surg Am. 2006 Jan; 88(1):55-70.
    View in: PubMed
  55. Meinel L, Fajardo R, Hofmann S, Langer R, Chen J, Snyder B, Vunjak-Novakovic G, Kaplan D. Silk implants for the healing of critical size bone defects. Bone. 2005 Nov; 37(5):688-98.
    View in: PubMed
  56. Snyder BD, Katz DA, Myers ER, Breitenbach MA, Emans JB. Bone density accumulation is not affected by brace treatment of idiopathic scoliosis in adolescent girls. J Pediatr Orthop. 2005 Jul-Aug; 25(4):423-8.
    View in: PubMed
  57. Miller BS, Taylor B, Widmann RF, Bae DS, Snyder BD, Waters PM. Cast immobilization versus percutaneous pin fixation of displaced distal radius fractures in children: a prospective, randomized study. J Pediatr Orthop. 2005 Jul-Aug; 25(4):490-4.
    View in: PubMed
  58. Meinel L, Karageorgiou V, Hofmann S, Fajardo R, Snyder B, Li C, Zichner L, Langer R, Vunjak-Novakovic G, Kaplan DL. Engineering bone-like tissue in vitro using human bone marrow stem cells and silk scaffolds. J Biomed Mater Res A. 2004 Oct 1; 71(1):25-34.
    View in: PubMed
  59. Hong J, Cabe GD, Tedrow JR, Hipp JA, Snyder BD. Failure of trabecular bone with simulated lytic defects can be predicted non-invasively by structural analysis. J Orthop Res. 2004 May; 22(3):479-86.
    View in: PubMed
  60. Meinel L, Karageorgiou V, Fajardo R, Snyder B, Shinde-Patil V, Zichner L, Kaplan D, Langer R, Vunjak-Novakovic G. Bone tissue engineering using human mesenchymal stem cells: effects of scaffold material and medium flow. Ann Biomed Eng. 2004 Jan; 32(1):112-22.
    View in: PubMed
  61. McCreery R, Dieringer J, Solak AO, Snyder B, Nowak AM, McGovern WR, DuVall S. Molecular rectification and conductance switching in carbon-based molecular junctions by structural rearrangement accompanying electron injection. J Am Chem Soc. 2003 Sep 3; 125(35):10748-58.
    View in: PubMed
  62. Abel MF, Damiano DL, Blanco JS, Conaway M, Miller F, Dabney K, Sutherland D, Chambers H, Dias L, Sarwark J, Killian J, Doyle S, Root L, LaPlaza J, Widmann R, Snyder B. Relationships among musculoskeletal impairments and functional health status in ambulatory cerebral palsy. J Pediatr Orthop. 2003 Jul-Aug; 23(4):535-41.
    View in: PubMed
  63. Boutis K, Komar L, Jaramillo D, Babyn P, Alman B, Snyder B, Mandl KD, Schuh S. Sensitivity of a clinical examination to predict need for radiography in children with ankle injuries: a prospective study. Lancet. 2001 Dec 22-29; 358(9299):2118-21.
    View in: PubMed
  64. Whealan KM, Kwak SD, Tedrow JR, Inoue K, Snyder BD. Noninvasive imaging predicts failure load of the spine with simulated osteolytic defects. J Bone Joint Surg Am. 2000 Sep; 82(9):1240-51.
    View in: PubMed
  65. Hong J, Hipp JA, Mulkern RV, Jaramillo D, Snyder BD. Magnetic resonance imaging measurements of bone density and cross-sectional geometry. Calcif Tissue Int. 2000 Jan; 66(1):74-8.
    View in: PubMed
  66. Waters PM, Mintzer CM, Hipp JA, Snyder BD. Noninvasive measurement of distal radius instability. J Hand Surg Am. 1997 Jul; 22(4):572-9.
    View in: PubMed
  67. Hipp JA, Jansujwicz A, Simmons CA, Snyder BD. Trabecular bone morphology from micro-magnetic resonance imaging. J Bone Miner Res. 1996 Feb; 11(2):286-97.
    View in: PubMed
  68. Lauer SA, Snyder B, Rodriguez E, Adamo A. Classification of orbital floor fractures. J Craniomaxillofac Trauma. 1996; 2(4):6-11.
    View in: PubMed
  69. Snyder BD, Zaltz I, Breitenbach MA, Kido TH, Myers ER, Emans JB. Does bracing affect bone density in adolescent scoliosis? Spine (Phila Pa 1976). 1995 Jul 15; 20(14):1554-60.
    View in: PubMed
  70. Snyder BD, Zaltz I, Hall JE, Emans JB. Predicting the integrity of vertebral bone screw fixation in anterior spinal instrumentation. Spine (Phila Pa 1976). 1995 Jul 15; 20(14):1568-74.
    View in: PubMed
  71. Snyder BD, Piazza S, Edwards WT, Hayes WC. Role of trabecular morphology in the etiology of age-related vertebral fractures. Calcif Tissue Int. 1993; 53 Suppl 1:S14-22.
    View in: PubMed
  72. Cheal EJ, Snyder BD, Nunamaker DM, Hayes WC. Trabecular bone remodeling around smooth and porous implants in an equine patellar model. J Biomech. 1987; 20(11-12):1121-34.
    View in: PubMed
  73. Cheal EJ, Hayes WC, Lee CH, Snyder BD, Miller J. Stress analysis of a condylar knee tibial component: influence of metaphyseal shell properties and cement injection depth. J Orthop Res. 1985; 3(4):424-34.
    View in: PubMed
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