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Anand Vaidya, M.D.

TitleInstructor in Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressBrigham and Womens Hospital, RFB 388
Div. of Endocrinology, Diabetes, and Hypertension,
221 Longwood Ave
Boston MA 02115
Phone617/732-5661
Fax617/732-5764

 Overview 
 overview
RESEARCH:
My research investigates adrenal disorders and how adrenal hormones influence cardiovascular disease in humans. I conduct patient oriented studies evaluating:

1) The etiology, diagnosis, and treatment of adrenal disorders, including: adrenal adenomas, adrenal carcinomas, pheochromocytoma-paraganglioma syndromes, hyperaldosteronsim, Cushing's syndrome, Addison's disease, adrenal insufficiency.
2) The interactions between adrenal hormones and calcium-regulatory hormones, and how they influence cardiovascular risk.


CLINICAL:
I am the Co-Director of the Center for Adrenal Disorders where I see patients with adrenal disorders (http://tinyurl.com/bwhadrenalcenter).


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Ghosh P, Sahoo R, Vaidya A, Cantel S, Kavishwar A, Goldfine A, Herring N, Bry L, Chorev M, Halperin JA. A specific and sensitive assay for blood levels of glycated CD59: A novel biomarker for diabetes. Am J Hematol. 2013 May 13.
    View in: PubMed
  2. Redig AJ, Vaidya A, Bienfang DC, Milligan T. Interactive medical case. A pain in the brain. N Engl J Med. 2013 Apr 11; 368(15):e20.
    View in: PubMed
  3. Wei K, Vaidya A, Rohloff P, Sun YP, Grad Y. Interactive medical case. A patient with fevers and fatigue. N Engl J Med. 2013 Feb 14; 368(7):e9.
    View in: PubMed
  4. Vaidya A, Underwood PC, Hopkins PN, Jeunemaitre X, Ferri C, Williams GH, Adler GK. Abnormal aldosterone physiology and cardiometabolic risk factors. Hypertension. 2013 Apr; 61(4):886-93.
    View in: PubMed
  5. Sacks Z, Vaidya A, Sharma N, Gottlieb B. A patient found unresponsive. N Engl J Med. 2012 Dec 13; 367(24):e36.
    View in: PubMed
  6. Vaidya A, Underwood PC, Annes JP, Sun B, Williams GH, Forman JP, Williams JS. The influence of sodium- and calcium-regulatory hormone interventions on adipocytokines in obesity and diabetes. Metabolism. 2013 Apr; 62(4):539-47.
    View in: PubMed
  7. Vaidya A, King LY, Lee LS, Tucker JK. Interactive medical case. A complex cause of pleuritic chest pain. N Engl J Med. 2012 Oct 11; 367(15):e21.
    View in: PubMed
  8. Vaidya A, Price CN, Lee YC. Interactive medical case. Disconnected. N Engl J Med. 2012 Aug 16; 367(7):e10.
    View in: PubMed
  9. Underwood PC, Chamarthi B, Williams JS, Vaidya A, Garg R, Adler GK, Grotzke MP, Staskus G, Wadwekar D, Hopkins PN, Ferri C, McCall A, McClain D, Williams GH. Nonmodulation as the mechanism for salt sensitivity of blood pressure in individuals with hypertension and type 2 diabetes mellitus. J Clin Endocrinol Metab. 2012 Oct; 97(10):3775-82.
    View in: PubMed
  10. Vaidya A, Ghoroghchian PP, Merola JF, Samuels MA. Interactive medical case. At a loss. N Engl J Med. 2012 Jun 14; 366(24):e37.
    View in: PubMed
  11. Min L, Vaidya A, Becker C. Association of ipilimumab therapy for advanced melanoma with secondary adrenal insufficiency: a case series. Endocr Pract. 2012 May-Jun; 18(3):351-5.
    View in: PubMed
  12. Vaidya A, Sun B, Larson C, Forman JP, Williams JS. Vitamin D3 therapy corrects the tissue sensitivity to angiotensin ii akin to the action of a converting enzyme inhibitor in obese hypertensives: an interventional study. J Clin Endocrinol Metab. 2012 Jul; 97(7):2456-65.
    View in: PubMed
  13. Vaidya A, Hurwitz S, Yialamas M, Min L, Garg R. Improving the management of diabetes in hospitalized patients: the results of a computer-based house staff training program. Diabetes Technol Ther. 2012 Jul; 14(7):610-8.
    View in: PubMed
  14. Vaidya A, Solomon DA, Fanta CH. Whistling in the dark. N Engl J Med. 2012 Apr 12; 366(15):e24.
    View in: PubMed
  15. Vaidya A, Forman JP. Vitamin D and vascular disease: the current and future status of vitamin D therapy in hypertension and kidney disease. Curr Hypertens Rep. 2012 Apr; 14(2):111-9.
    View in: PubMed
  16. Vaidya A, Dolan BM, Edlow BL, Rinne ML, McGinnis SM. Interactive medical case. A startling decline. N Engl J Med. 2012 Feb 9; 366(6):e11.
    View in: PubMed
  17. Vaidya A, Williams JS. Vitamin D and insulin sensitivity: can gene association and pharmacogenetic studies of the vitamin D receptor provide clarity? Metabolism. 2012 Jun; 61(6):759-61.
    View in: PubMed
  18. Larson C, Vaidya A, Sun B, Williams JS. Influence of dietary sodium modulation on electrocardiographic voltage criteria for left ventricular hypertrophy in normotensive individuals. J Investig Med. 2012 Jan; 60(1):39-43.
    View in: PubMed
  19. Ross JJ, Vaidya A, Gavin MC, Morse D, Partridge AH. Interactive medical case. Breathless. N Engl J Med. 2011 Dec 22; 365(25):e47.
    View in: PubMed
  20. Vaidya A, Williams JS. The relationship between vitamin D and the renin-angiotensin system in the pathophysiology of hypertension, kidney disease, and diabetes. Metabolism. 2012 Apr; 61(4):450-8.
    View in: PubMed
  21. Underwood PC, Chamarthi B, Williams JS, Sun B, Vaidya A, Raby BA, Lasky-Su J, Hopkins PN, Adler GK, Williams GH. Replication and meta-analysis of the gene-environment interaction between body mass index and the interleukin-6 promoter polymorphism with higher insulin resistance. Metabolism. 2012 May; 61(5):667-71.
    View in: PubMed
  22. Lee AI, Koo S, Vaidya A, Katz JT, Loscalzo J. Clinical problem-solving. A bird's-eye view of fever. N Engl J Med. 2011 Nov 3; 365(18):1727-32.
    View in: PubMed
  23. Vaidya A, Williams JS, Forman JP. The independent association between 25-hydroxyvitamin D and adiponectin and its relation with BMI in two large cohorts: the NHS and the HPFS. Obesity (Silver Spring). 2012 Jan; 20(1):186-91.
    View in: PubMed
  24. Vaidya A, Sun B, Forman JP, Hopkins PN, Brown NJ, Kolatkar NS, Williams GH, Williams JS. The Fok1 vitamin D receptor gene polymorphism is associated with plasma renin activity in Caucasians. Clin Endocrinol (Oxf). 2011 Jun; 74(6):783-90.
    View in: PubMed
  25. Vaidya A, Forman JP, Underwood PC, Hopkins PN, Williams GH, Pojoga LH, Williams JS. The influence of body mass index and renin-angiotensin-aldosterone system activity on the relationship between 25-hydroxyvitamin D and adiponectin in Caucasian men. Eur J Endocrinol. 2011 Jun; 164(6):995-1002.
    View in: PubMed
  26. Vaidya A, Kaiser UB, Levy BD, Loscalzo J. Clinical problem-solving. Lying low. N Engl J Med. 2011 Mar 3; 364(9):871-5.
    View in: PubMed
  27. Vaidya A, Pojoga L, Underwood PC, Forman JP, Hopkins PN, Williams GH, Williams JS. The association of plasma resistin with dietary sodium manipulation, the renin-angiotensin-aldosterone system, and 25-hydroxyvitamin D3 in human hypertension. Clin Endocrinol (Oxf). 2011 Mar; 74(3):294-9.
    View in: PubMed
  28. Vaidya A, Forman JP, Hopkins PN, Seely EW, Williams JS. 25-Hydroxyvitamin D is associated with plasma renin activity and the pressor response to dietary sodium intake in Caucasians. J Renin Angiotensin Aldosterone Syst. 2011 Sep; 12(3):311-9.
    View in: PubMed
  29. Ross JJ, Vaidya A, Kaiser UB. Interactive medical case. Lying low. N Engl J Med. 2011 Feb 10; 364(6):e10.
    View in: PubMed
  30. Vaidya A, Forman JP, Williams JS. Vitamin D and the vascular sensitivity to angiotensin II in obese Caucasians with hypertension. J Hum Hypertens. 2011 Nov; 25(11):672-8.
    View in: PubMed
  31. Min L, Vaidya A, Becker C. Thyroid autoimmunity and ophthalmopathy related to melanoma biological therapy. Eur J Endocrinol. 2011 Feb; 164(2):303-7.
    View in: PubMed
  32. Vaidya A, Forman JP. Vitamin D and hypertension: current evidence and future directions. Hypertension. 2010 Nov; 56(5):774-9.
    View in: PubMed
  33. Vaidya A, Morris CA, Ross JJ. Interactive medical case. Stalking the diagnosis. N Engl J Med. 2010 Feb 11; 362(6):e16.
    View in: PubMed
  34. Vaidya A, Bentley-Lewis R, Jeunemaitre X, Adler GK, Williams JS. Dietary sodium alters the prevalence of electrocardiogram determined left ventricular hypertrophy in hypertension. Am J Hypertens. 2009 Jun; 22(6):669-73.
    View in: PubMed
  35. Vaidya A, McMahon, GT. Journal of Clinical Outcomes Medicine. Initiating Insulin for Type 2 Diabetes: Strategies for Success. 2009; 16(3):127-136.
  36. Johnstone MT, Perez AS, Nasser I, Stewart R, Vaidya A, Al Ammary F, Schmidt B, Horowitz G, Dolgoff J, Hamilton J, Quist WC. Angiotensin receptor blockade with candesartan attenuates atherosclerosis, plaque disruption, and macrophage accumulation within the plaque in a rabbit model. Circulation. 2004 Oct 5; 110(14):2060-5.
    View in: PubMed
  37. Botnar RM, Perez AS, Witte S, Wiethoff AJ, Laredo J, Hamilton J, Quist W, Parsons EC, Vaidya A, Kolodziej A, Barrett JA, Graham PB, Weisskoff RM, Manning WJ, Johnstone MT. In vivo molecular imaging of acute and subacute thrombosis using a fibrin-binding magnetic resonance imaging contrast agent. Circulation. 2004 Apr 27; 109(16):2023-9.
    View in: PubMed
  38. Vaidya A, Suga H. Diverse roles of metal ions in acyl-transferase ribozymes. Biochemistry. 2001 Jun 19; 40(24):7200-10.
    View in: PubMed
  39. Sigel RK, Vaidya A, Pyle AM. Metal ion binding sites in a group II intron core. Nat Struct Biol. 2000 Dec; 7(12):1111-6.
    View in: PubMed
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