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Lizabeth A. Perkins, Ph.D.

TitleLecturer on Genetics
InstitutionHarvard Medical School
DepartmentGenetics
AddressHarvard Medical School
Genetics NRB 339
77 Avenue Louis Pasteur
Boston MA 02115
Phone617/724-1618
Fax617/726-2736

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Bergwitz C, Wee MJ, Sinha S, Huang J, Derobertis C, Mensah LB, Cohen J, Friedman A, Kulkarni M, Hu Y, Vinayagam A, Schnall-Levin M, Berger B, Perkins LA, Mohr SE, Perrimon N. Genetic determinants of phosphate response in Drosophila. PLoS One. 2013; 8(3):e56753.
    View in: PubMed
  2. Staller MV, Yan D, Randklev S, Bragdon MD, Wunderlich ZB, Tao R, Perkins LA, Depace AH, Perrimon N. Depleting Gene Activities in Early Drosophila Embryos with the "Maternal-Gal4-shRNA" System. Genetics. 2013 Jan; 193(1):51-61.
    View in: PubMed
  3. Ni JQ, Zhou R, Czech B, Liu LP, Holderbaum L, Yang-Zhou D, Shim HS, Tao R, Handler D, Karpowicz P, Binari R, Booker M, Brennecke J, Perkins LA, Hannon GJ, Perrimon N. A genome-scale shRNA resource for transgenic RNAi in Drosophila. Nat Methods. 2011 May; 8(5):405-7.
    View in: PubMed
  4. Perrimon N, Ni JQ, Perkins L. In vivo RNAi: today and tomorrow. Cold Spring Harb Perspect Biol. 2010 Aug; 2(8):a003640.
    View in: PubMed
  5. Ni JQ, Liu LP, Binari R, Hardy R, Shim HS, Cavallaro A, Booker M, Pfeiffer BD, Markstein M, Wang H, Villalta C, Laverty TR, Perkins LA, Perrimon N. A Drosophila resource of transgenic RNAi lines for neurogenetics. Genetics. 2009 Aug; 182(4):1089-100.
    View in: PubMed
  6. Ni JQ, Markstein M, Binari R, Pfeiffer B, Liu LP, Villalta C, Booker M, Perkins L, Perrimon N. Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster. Nat Methods. 2008 Jan; 5(1):49-51.
    View in: PubMed
  7. Lau GW, Goumnerov BC, Walendziewicz CL, Hewitson J, Xiao W, Mahajan-Miklos S, Tompkins RG, Perkins LA, Rahme LG. The Drosophila melanogaster toll pathway participates in resistance to infection by the gram-negative human pathogen Pseudomonas aeruginosa. Infect Immun. 2003 Jul; 71(7):4059-66.
    View in: PubMed
  8. Baker SE, Lorenzen JA, Miller SW, Bunch TA, Jannuzi AL, Ginsberg MH, Perkins LA, Brower DL. Genetic interaction between integrins and moleskin, a gene encoding a Drosophila homolog of importin-7. Genetics. 2002 Sep; 162(1):285-96.
    View in: PubMed
  9. Johnson Hamlet MR, Perkins LA. Analysis of corkscrew signaling in the Drosophila epidermal growth factor receptor pathway during myogenesis. Genetics. 2001 Nov; 159(3):1073-87.
    View in: PubMed
  10. Vincent S, Perkins LA, Perrimon N. Doublesex surprises. Cell. 2001 Aug 24; 106(4):399-402.
    View in: PubMed
  11. Lorenzen JA, Baker SE, Denhez F, Melnick MB, Brower DL, Perkins LA. Nuclear import of activated D-ERK by DIM-7, an importin family member encoded by the gene moleskin. Development. 2001 Apr; 128(8):1403-14.
    View in: PubMed
  12. Firth L, Manchester J, Lorenzen JA, Baron M, Perkins LA. Identification of genomic regions that interact with a viable allele of the Drosophila protein tyrosine phosphatase corkscrew. Genetics. 2000 Oct; 156(2):733-48.
    View in: PubMed
  13. Ghiglione C, Perrimon N, Perkins LA. Quantitative variations in the level of MAPK activity control patterning of the embryonic termini in Drosophila. Dev Biol. 1999 Jan 1; 205(1):181-93.
    View in: PubMed
  14. Perrimon N, Perkins LA. There must be 50 ways to rule the signal: the case of the Drosophila EGF receptor. Cell. 1997 Apr 4; 89(1):13-6.
    View in: PubMed
  15. Perkins LA, Johnson MR, Melnick MB, Perrimon N. The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila. Dev Biol. 1996 Nov 25; 180(1):63-81.
    View in: PubMed
  16. Perrimon N, Lu X, Hou XS, Hsu JC, Melnick MB, Chou TB, Perkins LA. Dissection of the Torso signal transduction pathway in Drosophila. Mol Reprod Dev. 1995 Dec; 42(4):515-22.
    View in: PubMed
  17. Noll E, Perkins LA, Mahowald AP, Perrimon N. Approaches to identify genes involved in Drosophila embryonic CNS development. J Neurobiol. 1993 Jun; 24(6):701-22.
    View in: PubMed
  18. Lu X, Perkins LA, Perrimon N. The torso pathway in Drosophila: a model system to study receptor tyrosine kinase signal transduction. Dev Suppl. 1993; 47-56.
    View in: PubMed
  19. Perkins LA, Larsen I, Perrimon N. corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso. Cell. 1992 Jul 24; 70(2):225-36.
    View in: PubMed
  20. Perkins LA, Perrimon N. The molecular genetics of tail development in Drosophila melanogaster. In Vivo. 1991 Sep-Oct; 5(5):521-31.
    View in: PubMed
  21. Zhang K, Chaillet JR, Perkins LA, Halazonetis TD, Perrimon N. Drosophila homolog of the mammalian jun oncogene is expressed during embryonic development and activates transcription in mammalian cells. Proc Natl Acad Sci U S A. 1990 Aug; 87(16):6281-5.
    View in: PubMed
  22. Siegfried E, Perkins LA, Capaci TM, Perrimon N. Putative protein kinase product of the Drosophila segment-polarity gene zeste-white3. Nature. 1990 Jun 28; 345(6278):825-9.
    View in: PubMed
  23. Perkins LA, Doctor JS, Zhang K, Stinson L, Perrimon N, Craig EA. Molecular and developmental characterization of the heat shock cognate 4 gene of Drosophila melanogaster. Mol Cell Biol. 1990 Jun; 10(6):3232-8.
    View in: PubMed
  24. Ng SC, Perkins LA, Conboy G, Perrimon N, Fishman MC. A Drosophila gene expressed in the embryonic CNS shares one conserved domain with the mammalian GAP-43. Development. 1989 Mar; 105(3):629-38.
    View in: PubMed
  25. O'Connor MB, Binari R, Perkins LA, Bender W. Alternative RNA products from the Ultrabithorax domain of the bithorax complex. EMBO J. 1988 Feb; 7(2):435-45.
    View in: PubMed
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