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Ronald Charles Desrosiers, Ph.D.

TitleProfessor of Microbiology and Immunobiology, Emeritus
InstitutionHarvard Medical School
DepartmentEmeritus
AddressN.E. Reg. Primate Research Ctr
1 Pine Hill Dr
Southborough MA 01772
Phone508/624-8042
Fax508/624-8190

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Hahn AS, Desrosiers RC. Rhesus monkey rhadinovirus uses eph family receptors for entry into B cells and endothelial cells but not fibroblasts. PLoS Pathog. 2013 May; 9(5):e1003360.
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  2. Manrique J, Piatak M, Lauer W, Johnson W, Mansfield K, Lifson J, Desrosiers R. Influence of mismatch of env sequences on vaccine protection by live attenuated simian immunodeficiency virus. J Virol. 2013 Jul; 87(13):7246-54.
    View in: PubMed
  3. Del Prete GQ, Scarlotta M, Newman L, Reid C, Parodi LM, Roser JD, Oswald K, Marx PA, Miller CJ, Desrosiers RC, Barouch DH, Pal R, Piatak M, Chertova E, Giavedoni LD, O'Connor DH, Lifson JD, Keele BF. Comparative characterization of transfection- and infection-derived simian immunodeficiency virus challenge stocks for in vivo nonhuman primate studies. J Virol. 2013 Apr; 87(8):4584-95.
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  4. Postler TS, Desrosiers RC. The Tale of the Long Tail: the Cytoplasmic Domain of HIV-1 gp41. J Virol. 2013 Jan; 87(1):2-15.
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  5. Martinez-Navio JM, Desrosiers RC. Neutralizing Capacity of Monoclonal Antibodies That Recognize Peptide Sequences Underlying the Carbohydrates on gp41 of Simian Immunodeficiency Virus. J Virol. 2012 Dec; 86(23):12484-93.
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  6. Alpert MD, Harvey JD, Lauer WA, Reeves RK, Piatak M, Carville A, Mansfield KG, Lifson JD, Li W, Desrosiers RC, Johnson RP, Evans DT. ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge. PLoS Pathog. 2012; 8(8):e1002890.
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  7. Postler TS, Desrosiers RC. The cytoplasmic domain of the HIV-1 glycoprotein gp41 induces NF-?B activation through TGF-ß-activated kinase 1. Cell Host Microbe. 2012 Feb 16; 11(2):181-93.
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  8. Postler TS, Martinez-Navio JM, Yuste E, Desrosiers RC. Evidence against extracellular exposure of a highly immunogenic region in the C-terminal domain of the simian immunodeficiency virus gp41 transmembrane protein. J Virol. 2012 Jan; 86(2):1145-57.
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  9. Hollingsworth MT, Hart GW, Paulson JC, Stansell E, Canis K, Huang IC, Panico M, Morris H, Haslam S, Farzan M, Dell A, Desrosiers R, von Itzstein M, Matroscovich M, Luther KB, Hülsmeier AJ, Schegg B, Hennet T, Nycholat C, McBride R, Ekiert D, Xu R, Peng W, Razi N, Gilbert M, Wakarchuk W, Wilson IA, Paulson JC, Gahlay G, Geisler C, Aumiller JJ, Moremen K, Steel J, Labaer J, Jarvis DL, Drickamer K, Taylor M, Nizet V, Rabinovich G, Lewis C, Cobb B, Kawasaki N, Nycholat C, Rademacher C, Chen W, Vela J, Maricic I, Crocker P, Kumar V, Kronenberg M, Paulson J, Glenn K, Mallinger A, Wen H, Srivastava L, Tundup S, Harn D, Menon AK, Yamaguchi Y, Mkhikian H, Grigorian A, Li C, Chen HL, Newton B, Zhou RW, Beeton C, Torossian S, Tatarian GG, Lee SU, Lau K, Walker E, Siminovitch KA, Chandy KG, Yu Z, Dennis JW, Demetriou M, Pandey MS, Baggenstoss BA, Washburn JL, Weigel PH, Chen CI, Keusch JJ, Klein D, Hofsteenge J, Gut H, Szymanski C, Feldman M, Schaffer C, Gao Y, Strum S, Liu B, Schutzbach JS, Druzhinina TN, Utkina NS, Torgov VI, Szarek WA, Wang L, Brockhausen I, Hitchen P, Peyfoon E, Meyer B, Haslam S, Albers SV, Dell A, Yu Z, Chen C, Liu B, Newburg DS, Jin C, Dinglasan RD, Beverley SM, Guo H, Novozhilova N, Hickerson S, Elnaiem DE, Sacks D, Turco SJ, McKay D, Castro E, Takahashi H, Straus AH, Stalnaker SH, Live D, Boons GJ, Moremen K, Wells L, Stuart R, Aoki K, Boccuto L, Zhang Q, Wang H, Bartel F, Fan X, Saul R, Chaubey A, Yang X, Steet R, Schwartz C, Tiemeyer M, Pierce M, Kraushaar DC, Condac E, Yamaguchi Y, Wang L, Nakato H, Nishihara S, Sasaki N, Hirano K, Nasirikenari M, Collins CC, Lau JT, Devarapu SK, Jeyaweerasinkam S, Albiez RS, Kiessling L, Gu J, Clark GF, Gagneux P, Ulm C, Mahavadi P, Müller S, Rinné S, Geyer H, Gerardy-Schahn R, Mühlenhoff M, Günther A, Geyer R, Galuska SP, Shibata T, Sugihara K, Nakayama J, Fukuda M, Fukuda MN, Ishikawa A, Terao M, Kimura A, Kato A, Katayama I, Taniguchi N, Miyoshi E, Aderem A, Yoneyama T, Angata K, Bao X, Chanda S, Fukuda M, Boons GJ, Lowe J, Sonon R, Ishihara M, Talabnin K, Wang Z, Black I, Naran R, Heiss C, Azadi P, Hurum D, Rohrer J, Balland A, Valliere-Douglass J, Kodama P, Mujacic M, Eakin C, Brady L, Wang WC, Wallace A, Treuheit M, Reddy P, Schuman B, Fisher S, Borisova S, Coates L, Langan P, Evans S, Yang SJ, Zhang H, Hizal DB, Tian Y, Sarkaria V, Betenbaugh M, Zhang H, Lütteke T, Agravat S, Cholleti S, Morris T, Saltz J, Song X, Cummings R, Smith D, Hofhine T, Nishida C, Mialy R, Sophie D, Sebastien F, Patricia C, Eric S, Stephane H, Mokros D, Joosten RP, Dominik A, Vriend G, Lütteke T, Nguyen LD, Martinez J, Hinderlich S, Reissig HU, Reutter W, Fan H, Saenger W, Moniot S, Asada H, Nakahara T, Miura Y, Stevenson T, Yamazaki T, De Castro C, Burr T, Lanzetta R, Molinaro A, Parrilli M, Sule S, Gerken TA, Revpredo L, Thome J, Gerken TA, Cardenas G, Almeida I, Leung MY, Yan S, Paschinger K, Bleuler-Martinez S, Jantsch V, Wilson I, Yoshimura Y, Adlercreutz D, Mannerstedt K, Wakarchuk WW, Dovichi NJ, Hindsgaul O, Palcic MM, Chandrasekaran A, Bharadwaj R, Deng K, Adams P, Singh A, Datta A, Konasani V, Imamura A, Lowry T, Scaman C, Zhao Y, Zhou YD, Yang K, Zhang XL, Leymarie N, Hartshorn K, White M, Cafarella T, Seaton B, Rynkiewicz M, Zaia J, Acosta-Blanco I, Ortega-Francisco S, Dionisio-Vicuña M, Hernandez-Flores M, Fuentes-Romero L, Newburg D, Soto-Ramirez LE, Ruiz-Palacios G, Viveros-Rogel M, Tong C, Li W, Kong L, Qu M, Jin Q, Lukyanov P, Li W, Tong C, Zhang W, Qu M, Jin Q, Chicalovets I, Molchanova V, Lukyanov P, Wu AM, Liu JH, Yang WH, Nussbaum C, Grewal PK, Sperandio M, Marth JD, Yu R, Usuki S, Wu HC, O'Brien D, Piskarev V, Ramadugu SK, Kashyap HK, Ghirlanda G, Margulis C, Brewer C, Gomery K, Müller-Loennies S, Brooks CL, Brade L, Kosma P, Di Padova F, Brade H, Evans SV, Asakawa K, Kawakami K, Kushi Y, Suzuki Y, Nozaki H, Itonori S, Malik S, Lebeer S, Petrova M, Balzarini J, Vanderleyden J, Naito-Matsui Y, Takematsu H, Murata K, Kozutsumi Y, Subedi GP, Satoh T, Hanashima S, et al. Program and abstracts for the 2011 Meeting of the Society for Glycobiology. Glycobiology. 2011 Nov; 21(11):1454-531.
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  10. Bilello JP, Manrique JM, Shin YC, Lauer W, Li W, Lifson JD, Mansfield KG, Johnson RP, Desrosiers RC. Vaccine protection against simian immunodeficiency virus in monkeys using recombinant gamma-2 herpesvirus. J Virol. 2011 Dec; 85(23):12708-20.
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  11. Shin YC, Desrosiers RC. Rhesus monkey rhadinovirus ORF57 induces gH and gL glycoprotein expression through posttranscriptional accumulation of target mRNAs. J Virol. 2011 Aug; 85(15):7810-7.
    View in: PubMed
  12. Stansell E, Desrosiers RC. Functional contributions of carbohydrate on AIDS virus glycoprotein. Yale J Biol Med. 2010 Dec; 83(4):201-8.
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  13. Stansell E, Canis K, Haslam SM, Dell A, Desrosiers RC. Simian immunodeficiency virus from the sooty mangabey and rhesus macaque is modified with O-linked carbohydrate. J Virol. 2011 Jan; 85(1):582-95.
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  14. Bixby JG, Laur O, Johnson WE, Desrosiers RC. Diversity of envelope genes from an uncloned stock of SIVmac251. AIDS Res Hum Retroviruses. 2010 Oct; 26(10):1115-31.
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  15. Stansell E, Desrosiers RC. Fundamental difference in the content of high-mannose carbohydrate in the HIV-1 and HIV-2 lineages. J Virol. 2010 Sep; 84(18):8998-9009.
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  16. O'Connor SL, Lhost JJ, Becker EA, Detmer AM, Johnson RC, Macnair CE, Wiseman RW, Karl JA, Greene JM, Burwitz BJ, Bimber BN, Lank SM, Tuscher JJ, Mee ET, Rose NJ, Desrosiers RC, Hughes AL, Friedrich TC, Carrington M, O'Connor DH. MHC heterozygote advantage in simian immunodeficiency virus-infected Mauritian cynomolgus macaques. Sci Transl Med. 2010 Mar 10; 2(22):22ra18.
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  17. Shin YC, Jones LR, Manrique J, Lauer W, Carville A, Mansfield KG, Desrosiers RC. Glycoprotein gene sequence variation in rhesus monkey rhadinovirus. Virology. 2010 May 10; 400(2):175-86.
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  18. Johnson PR, Schnepp BC, Zhang J, Connell MJ, Greene SM, Yuste E, Desrosiers RC, Clark KR. Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys. Nat Med. 2009 Aug; 15(8):901-6.
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  19. Yuste E, Bixby J, Lifson J, Sato S, Johnson W, Desrosiers R. Glycosylation of gp41 of simian immunodeficiency virus shields epitopes that can be targets for neutralizing antibodies. J Virol. 2008 Dec; 82(24):12472-86.
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  20. Laird ME, Igarashi T, Martin MA, Desrosiers RC. Importance of the V1/V2 loop region of simian-human immunodeficiency virus envelope glycoprotein gp120 in determining the strain specificity of the neutralizing antibody response. J Virol. 2008 Nov; 82(22):11054-65.
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  21. Morgan C, Marthas M, Miller C, Duerr A, Cheng-Mayer C, Desrosiers R, Flores J, Haigwood N, Hu SL, Johnson RP, Lifson J, Montefiori D, Moore J, Robert-Guroff M, Robinson H, Self S, Corey L. The use of nonhuman primate models in HIV vaccine development. PLoS Med. 2008 Aug 12; 5(8):e173.
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  22. Sato S, Yuste E, Lauer WA, Chang EH, Morgan JS, Bixby JG, Lifson JD, Desrosiers RC, Johnson WE. Potent antibody-mediated neutralization and evolution of antigenic escape variants of simian immunodeficiency virus strain SIVmac239 in vivo. J Virol. 2008 Oct; 82(19):9739-52.
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  23. Bilello JP, Morgan JS, Desrosiers RC. Extreme dependence of gH and gL expression on ORF57 and association with highly unusual codon usage in rhesus monkey rhadinovirus. J Virol. 2008 Jul; 82(14):7231-7.
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  24. Mansfield K, Lang SM, Gauduin MC, Sanford HB, Lifson JD, Johnson RP, Desrosiers RC. Vaccine protection by live, attenuated simian immunodeficiency virus in the absence of high-titer antibody responses and high-frequency cellular immune responses measurable in the periphery. J Virol. 2008 Apr; 82(8):4135-48.
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  25. Laird ME, Desrosiers RC. Infectivity and neutralization of simian immunodeficiency virus with FLAG epitope insertion in gp120 variable loops. J Virol. 2007 Oct; 81(20):10838-48.
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  26. Marzi A, Mitchell DA, Chaipan C, Fisch T, Doms RW, Carrington M, Desrosiers RC, Pöhlmann S. Modulation of HIV and SIV neutralization sensitivity by DC-SIGN and mannose-binding lectin. Virology. 2007 Nov 25; 368(2):322-30.
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  27. Schäfer A, Cai X, Bilello JP, Desrosiers RC, Cullen BR. Cloning and analysis of microRNAs encoded by the primate gamma-herpesvirus rhesus monkey rhadinovirus. Virology. 2007 Jul 20; 364(1):21-7.
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  28. Beddows S, Franti M, Dey AK, Kirschner M, Iyer SP, Fisch DC, Ketas T, Yuste E, Desrosiers RC, Klasse PJ, Maddon PJ, Olson WC, Moore JP. A comparative immunogenicity study in rabbits of disulfide-stabilized, proteolytically cleaved, soluble trimeric human immunodeficiency virus type 1 gp140, trimeric cleavage-defective gp140 and monomeric gp120. Virology. 2007 Apr 10; 360(2):329-40.
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  29. Gauduin MC, Yu Y, Barabasz A, Carville A, Piatak M, Lifson JD, Desrosiers RC, Johnson RP. Induction of a virus-specific effector-memory CD4+ T cell response by attenuated SIV infection. J Exp Med. 2006 Nov 27; 203(12):2661-72.
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  30. Ahuja SK, Aiuti F, Berkhout B, Biberfeld P, Burton DR, Colizzi V, Deeks SG, Desrosiers RC, Dierich MP, Doms RW, Emerman M, Gallo RC, Girard M, Greene WC, Hoxie JA, Hunter E, Klein G, Korber B, Kuritzkes DR, Lederman MM, Malim MH, Marx PA, McCune JM, McMichael A, Miller C, Miller V, Montagnier L, Montefiori DC, Moore JP, Nixon DF, Overbaugh J, Pauza CD, Richman DD, Saag MS, Sattentau Q, Schooley RT, Shattock R, Shaw GM, Stevenson M, Trkola A, Wainberg MA, Weiss RA, Wolinsky S, Zack JA. A plea for justice for jailed medical workers. Science. 2006 Nov 10; 314(5801):924-5.
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  31. Kaur A, Sanford HB, Garry D, Lang S, Klumpp SA, Watanabe D, Bronson RT, Lifson JD, Rosati M, Pavlakis GN, Felber BK, Knipe DM, Desrosiers RC. Ability of herpes simplex virus vectors to boost immune responses to DNA vectors and to protect against challenge by simian immunodeficiency virus. Virology. 2007 Jan 20; 357(2):199-214.
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  32. Desrosiers R, Derosiers R, Bonetta L. Chasing viruses. Biotechniques. 2006 Jul; 41(1):21.
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  33. Bilello JP, Lang SM, Wang F, Aster JC, Desrosiers RC. Infection and persistence of rhesus monkey rhadinovirus in immortalized B-cell lines. J Virol. 2006 Apr; 80(7):3644-9.
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  34. Cai X, Schäfer A, Lu S, Bilello JP, Desrosiers RC, Edwards R, Raab-Traub N, Cullen BR. Epstein-Barr virus microRNAs are evolutionarily conserved and differentially expressed. PLoS Pathog. 2006 Mar; 2(3):e23.
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  35. Yuste E, Sanford HB, Carmody J, Bixby J, Little S, Zwick MB, Greenough T, Burton DR, Richman DD, Desrosiers RC, Johnson WE. Simian immunodeficiency virus engrafted with human immunodeficiency virus type 1 (HIV-1)-specific epitopes: replication, neutralization, and survey of HIV-1-positive plasma. J Virol. 2006 Mar; 80(6):3030-41.
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  36. Bilello JP, Morgan JS, Damania B, Lang SM, Desrosiers RC. A genetic system for rhesus monkey rhadinovirus: use of recombinant virus to quantitate antibody-mediated neutralization. J Virol. 2006 Feb; 80(3):1549-62.
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  37. Koff WC, Johnson PR, Watkins DI, Burton DR, Lifson JD, Hasenkrug KJ, McDermott AB, Schultz A, Zamb TJ, Boyle R, Desrosiers RC. HIV vaccine design: insights from live attenuated SIV vaccines. Nat Immunol. 2006 Jan; 7(1):19-23.
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  38. Pikora CA, Wittish C, Desrosiers RC. p6gag of human and simian immunodeficiency viruses is tolerant to small in-frame deletions downstream of the late domain. Virology. 2006 Mar 15; 346(2):479-89.
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  39. Yuste E, Johnson W, Pavlakis GN, Desrosiers RC. Virion envelope content, infectivity, and neutralization sensitivity of simian immunodeficiency virus. J Virol. 2005 Oct; 79(19):12455-63.
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  40. Pikora C, Wittish C, Desrosiers RC. Identification of two N-linked glycosylation sites within the core of the simian immunodeficiency virus glycoprotein whose removal enhances sensitivity to soluble CD4. J Virol. 2005 Oct; 79(19):12575-83.
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  41. Schmitz JE, Johnson RP, McClure HM, Manson KH, Wyand MS, Kuroda MJ, Lifton MA, Khunkhun RS, McEvers KJ, Gillis J, Piatak M, Lifson JD, Grosschupff G, Racz P, Tenner-Racz K, Rieber EP, Kuus-Reichel K, Gelman RS, Letvin NL, Montefiori DC, Ruprecht RM, Desrosiers RC, Reimann KA. Effect of CD8+ lymphocyte depletion on virus containment after simian immunodeficiency virus SIVmac251 challenge of live attenuated SIVmac239delta3-vaccinated rhesus macaques. J Virol. 2005 Jul; 79(13):8131-41.
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  42. Evans DT, Bricker JE, Sanford HB, Lang S, Carville A, Richardson BA, Piatak M, Lifson JD, Mansfield KG, Desrosiers RC. Immunization of macaques with single-cycle simian immunodeficiency virus (SIV) stimulates diverse virus-specific immune responses and reduces viral loads after challenge with SIVmac239. J Virol. 2005 Jun; 79(12):7707-20.
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  43. Blancou P, Evans DT, Desrosiers RC. PRA1 co-localizes with envelope but does not influence primate lentivirus production, infectivity or envelope incorporation. J Gen Virol. 2005 Jun; 86(Pt 6):1785-90.
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  44. Cook HL, Lytle JR, Mischo HE, Li MJ, Rossi JJ, Silva DP, Desrosiers RC, Steitz JA. Small nuclear RNAs encoded by Herpesvirus saimiri upregulate the expression of genes linked to T cell activation in virally transformed T cells. Curr Biol. 2005 May 24; 15(10):974-9.
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  45. Kim EY, Busch M, Abel K, Fritts L, Bustamante P, Stanton J, Lu D, Wu S, Glowczwskie J, Rourke T, Bogdan D, Piatak M, Lifson JD, Desrosiers RC, Wolinsky S, Miller CJ. Retroviral recombination in vivo: viral replication patterns and genetic structure of simian immunodeficiency virus (SIV) populations in rhesus macaques after simultaneous or sequential intravaginal inoculation with SIVmac239Deltavpx/Deltavpr and SIVmac239Deltanef. J Virol. 2005 Apr; 79(8):4886-95.
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  46. Swigut T, Alexander L, Morgan J, Lifson J, Mansfield KG, Lang S, Johnson RP, Skowronski J, Desrosiers R. Impact of Nef-mediated downregulation of major histocompatibility complex class I on immune response to simian immunodeficiency virus. J Virol. 2004 Dec; 78(23):13335-44.
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  47. Borda JT, Alvarez X, Kondova I, Aye P, Simon MA, Desrosiers RC, Lackner AA. Cell tropism of simian immunodeficiency virus in culture is not predictive of in vivo tropism or pathogenesis. Am J Pathol. 2004 Dec; 165(6):2111-22.
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  48. Burton DR, Desrosiers RC, Johnson PR, Koff WC. An AIDS vaccine: no time to give up. Lancet. 2004 Nov 27-Dec 3; 364(9449):1938.
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  49. Evans DT, Bricker JE, Desrosiers RC. A novel approach for producing lentiviruses that are limited to a single cycle of infection. J Virol. 2004 Nov; 78(21):11715-25.
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  50. Yuste E, Reeves JD, Doms RW, Desrosiers RC. Modulation of Env content in virions of simian immunodeficiency virus: correlation with cell surface expression and virion infectivity. J Virol. 2004 Jul; 78(13):6775-85.
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  51. Burton DR, Desrosiers RC, Doms RW, Koff WC, Kwong PD, Moore JP, Nabel GJ, Sodroski J, Wilson IA, Wyatt RT. HIV vaccine design and the neutralizing antibody problem. Nat Immunol. 2004 Mar; 5(3):233-6.
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  52. Desrosiers RC. Prospects for an AIDS vaccine. Nat Med. 2004 Mar; 10(3):221-3.
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  53. Friedrich TC, Dodds EJ, Yant LJ, Vojnov L, Rudersdorf R, Cullen C, Evans DT, Desrosiers RC, Mothé BR, Sidney J, Sette A, Kunstman K, Wolinsky S, Piatak M, Lifson J, Hughes AL, Wilson N, O'Connor DH, Watkins DI. Reversion of CTL escape-variant immunodeficiency viruses in vivo. Nat Med. 2004 Mar; 10(3):275-81.
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  54. Cole KS, Steckbeck JD, Rowles JL, Desrosiers RC, Montelaro RC. Removal of N-linked glycosylation sites in the V1 region of simian immunodeficiency virus gp120 results in redirection of B-cell responses to V3. J Virol. 2004 Feb; 78(3):1525-39.
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  55. Renne R, Dittmer D, Kedes D, Schmidt K, Desrosiers RC, Luciw PA, Ganem D. Experimental transmission of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) to SIV-positive and SIV-negative rhesus macaques. J Med Primatol. 2004 Feb; 33(1):1-9.
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  56. Burton DR, Desrosiers RC, Doms RW, Feinberg MB, Gallo RC, Hahn B, Hoxie JA, Hunter E, Korber B, Landay A, Lederman MM, Lieberman J, McCune JM, Moore JP, Nathanson N, Picker L, Richman D, Rinaldo C, Stevenson M, Watkins DI, Wolinsky SM, Zack JA. Public health. A sound rationale needed for phase III HIV-1 vaccine trials. Science. 2004 Jan 16; 303(5656):316.
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  57. Johnson WE, Sanford H, Schwall L, Burton DR, Parren PW, Robinson JE, Desrosiers RC. Assorted mutations in the envelope gene of simian immunodeficiency virus lead to loss of neutralization resistance against antibodies representing a broad spectrum of specificities. J Virol. 2003 Sep; 77(18):9993-10003.
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  58. Alexander L, Illyinskii PO, Lang SM, Means RE, Lifson J, Mansfield K, Desrosiers RC. Determinants of increased replicative capacity of serially passaged simian immunodeficiency virus with nef deleted in rhesus monkeys. J Virol. 2003 Jun; 77(12):6823-35.
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  59. Kaur A, Kassis N, Hale CL, Simon M, Elliott M, Gomez-Yafal A, Lifson JD, Desrosiers RC, Wang F, Barry P, Mach M, Johnson RP. Direct relationship between suppression of virus-specific immunity and emergence of cytomegalovirus disease in simian AIDS. J Virol. 2003 May; 77(10):5749-58.
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  60. Evans DT, Chen LM, Gillis J, Lin KC, Harty B, Mazzara GP, Donis RO, Mansfield KG, Lifson JD, Desrosiers RC, Galán JE, Johnson RP. Mucosal priming of simian immunodeficiency virus-specific cytotoxic T-lymphocyte responses in rhesus macaques by the Salmonella type III secretion antigen delivery system. J Virol. 2003 Feb; 77(4):2400-9.
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  61. Johnson WE, Lifson JD, Lang SM, Johnson RP, Desrosiers RC. Importance of B-cell responses for immunological control of variant strains of simian immunodeficiency virus. J Virol. 2003 Jan; 77(1):375-81.
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  62. Allen TM, Jing P, Calore B, Horton H, O'Connor DH, Hanke T, Piekarczyk M, Ruddersdorf R, Mothé BR, Emerson C, Wilson N, Lifson JD, Belyakov IM, Berzofsky JA, Wang C, Allison DB, Montefiori DC, Desrosiers RC, Wolinsky S, Kunstman KJ, Altman JD, Sette A, McMichael AJ, Watkins DI. Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection. J Virol. 2002 Oct; 76(20):10507-11.
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  63. Lifson JD, Piatak M, Rossio JL, Bess J, Chertova E, Schneider D, Kiser R, Coalter V, Poore B, Imming R, Desrosiers RC, Henderson LE, Arthur LO. Whole inactivated SIV virion vaccines with functional envelope glycoproteins: safety, immunogenicity, and activity against intrarectal challenge. J Med Primatol. 2002 Aug; 31(4-5):205-16.
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  64. Horton H, Vogel TU, Carter DK, Vielhuber K, Fuller DH, Shipley T, Fuller JT, Kunstman KJ, Sutter G, Montefiori DC, Erfle V, Desrosiers RC, Wilson N, Picker LJ, Wolinsky SM, Wang C, Allison DB, Watkins DI. Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression following challenge with pathogenic SIVmac239. J Virol. 2002 Jul; 76(14):7187-202.
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  65. Soderberg K, Denekamp L, Nikiforow S, Sautter K, Desrosiers RC, Alexander L. A nucleotide substitution in the tRNA(Lys) primer binding site dramatically increases replication of recombinant simian immunodeficiency virus containing a human immunodeficiency virus type 1 reverse transcriptase. J Virol. 2002 Jun; 76(11):5803-6.
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  66. Allen TM, Mortara L, Mothé BR, Liebl M, Jing P, Calore B, Piekarczyk M, Ruddersdorf R, O'Connor DH, Wang X, Wang C, Allison DB, Altman JD, Sette A, Desrosiers RC, Sutter G, Watkins DI. Tat-vaccinated macaques do not control simian immunodeficiency virus SIVmac239 replication. J Virol. 2002 Apr; 76(8):4108-12.
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  67. Puffer BA, Pöhlmann S, Edinger AL, Carlin D, Sanchez MD, Reitter J, Watry DD, Fox HS, Desrosiers RC, Doms RW. CD4 independence of simian immunodeficiency virus Envs is associated with macrophage tropism, neutralization sensitivity, and attenuated pathogenicity. J Virol. 2002 Mar; 76(6):2595-605.
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  68. Zondervan K, Cardon L, Desrosiers R, Hyde D, Kemnitz J, Mansfield K, Roberts J, Scheffler J, Weeks DE, Kennedy S. The genetic epidemiology of spontaneous endometriosis in the rhesus monkey. Ann N Y Acad Sci. 2002 Mar; 955:233-8; discussion 293-5, 396-406.
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  69. Johnson WE, Morgan J, Reitter J, Puffer BA, Czajak S, Doms RW, Desrosiers RC. A replication-competent, neutralization-sensitive variant of simian immunodeficiency virus lacking 100 amino acids of envelope. J Virol. 2002 Mar; 76(5):2075-86.
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  70. Johnson WE, Desrosiers RC. Viral persistence: HIV's strategies of immune system evasion. Annu Rev Med. 2002; 53:499-518.
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  71. Evans DT, Tillman KC, Desrosiers RC. Envelope glycoprotein cytoplasmic domains from diverse lentiviruses interact with the prenylated Rab acceptor. J Virol. 2002 Jan; 76(1):327-37.
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  72. Johnson WE, Sauvron JM, Desrosiers RC. Conserved, N-linked carbohydrates of human immunodeficiency virus type 1 gp41 are largely dispensable for viral replication. J Virol. 2001 Dec; 75(23):11426-36.
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  73. Murphy WJ, Page JE, Smith C, Desrosiers RC, O'Brien SJ. A radiation hybrid mapping panel for the rhesus macaque. J Hered. 2001 Nov-Dec; 92(6):516-9.
    View in: PubMed
  74. Kaur A, Alexander L, Staprans SI, Denekamp L, Hale CL, McClure HM, Feinberg MB, Desrosiers RC, Johnson RP. Emergence of cytotoxic T lymphocyte escape mutations in nonpathogenic simian immunodeficiency virus infection. Eur J Immunol. 2001 Nov; 31(11):3207-17.
    View in: PubMed
  75. Lifson JD, Rossio JL, Piatak M, Parks T, Li L, Kiser R, Coalter V, Fisher B, Flynn BM, Czajak S, Hirsch VM, Reimann KA, Schmitz JE, Ghrayeb J, Bischofberger N, Nowak MA, Desrosiers RC, Wodarz D. Role of CD8(+) lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment. J Virol. 2001 Nov; 75(21):10187-99.
    View in: PubMed
  76. Newstein MC, Desrosiers RC. Effects of reverse-transcriptase mutations M184V and E89G on simian immunodeficiency virus in Rhesus monkeys. J Infect Dis. 2001 Nov 15; 184(10):1262-7.
    View in: PubMed
  77. Evans DT, Desrosiers RC. Immune evasion strategies of the primate lentiviruses. Immunol Rev. 2001 Oct; 183:141-58.
    View in: PubMed
  78. Damania B, Desrosiers RC. Simian homologues of human herpesvirus 8. Philos Trans R Soc Lond B Biol Sci. 2001 Apr 29; 356(1408):535-43.
    View in: PubMed
  79. Means RE, Matthews T, Hoxie JA, Malim MH, Kodama T, Desrosiers RC. Ability of the V3 loop of simian immunodeficiency virus to serve as a target for antibody-mediated neutralization: correlation of neutralization sensitivity, growth in macrophages, and decreased dependence on CD4. J Virol. 2001 Apr; 75(8):3903-15.
    View in: PubMed
  80. Alexander L, Denekamp L, Czajak S, Desrosiers RC. Suboptimal nucleotides in the infectious, pathogenic simian immunodeficiency virus clone SIVmac239. J Virol. 2001 Apr; 75(8):4019-22.
    View in: PubMed
  81. Desrosiers RC. Nonhuman Lentiviruses. Fields Vriology. Knipe D and Howley P (eds.). 2001; 2095-2121.
  82. Desrosiers R. Retroviral recombination as an adjunct to viral propagation and pathogenesis. Dev Biol (Basel). 2001; 106:213-5; discussion 215-6, 253-63.
    View in: PubMed
  83. Desrosiers RC. Retroviral Recombination as an Adjunct to Viral Propagation and Pathogenesis. Evolving Scientific and Regulatory Perspectives on Cell Substrates for Vaccine Development. Brown F, Lewis AM, Peden K, Kraus P (eds.). 2001; 106.
  84. Means RE, Desrosiers RC. Resistance of native, oligomeric envelope on simian immunodeficiency virus to digestion by glycosidases. J Virol. 2000 Dec; 74(23):11181-90.
    View in: PubMed
  85. Mori K, Rosenzweig M, Desrosiers RC. Mechanisms for adaptation of simian immunodeficiency virus to replication in alveolar macrophages. J Virol. 2000 Nov; 74(22):10852-9.
    View in: PubMed
  86. Mills J, Desrosiers R, Rud E, Almond N. Live attenuated HIV vaccines: a proposal for further research and development. AIDS Res Hum Retroviruses. 2000 Oct 10; 16(15):1453-61.
    View in: PubMed
  87. Allen TM, O'Connor DH, Jing P, Dzuris JL, Mothé BR, Vogel TU, Dunphy E, Liebl ME, Emerson C, Wilson N, Kunstman KJ, Wang X, Allison DB, Hughes AL, Desrosiers RC, Altman JD, Wolinsky SM, Sette A, Watkins DI. Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia. Nature. 2000 Sep 21; 407(6802):386-90.
    View in: PubMed
  88. Murphy CG, Lucas WT, Means RE, Czajak S, Hale CL, Lifson JD, Kaur A, Johnson RP, Knipe DM, Desrosiers RC. Vaccine protection against simian immunodeficiency virus by recombinant strains of herpes simplex virus. J Virol. 2000 Sep; 74(17):7745-54.
    View in: PubMed
  89. Alexander L, Weiskopf E, Greenough TC, Gaddis NC, Auerbach MR, Malim MH, O'Brien SJ, Walker BD, Sullivan JL, Desrosiers RC. Unusual polymorphisms in human immunodeficiency virus type 1 associated with nonprogressive infection. J Virol. 2000 May; 74(9):4361-76.
    View in: PubMed
  90. Alexander L, Denekamp L, Knapp A, Auerbach MR, Damania B, Desrosiers RC. The primary sequence of rhesus monkey rhadinovirus isolate 26-95: sequence similarities to Kaposi's sarcoma-associated herpesvirus and rhesus monkey rhadinovirus isolate 17577. J Virol. 2000 Apr; 74(7):3388-98.
    View in: PubMed
  91. Damania B, DeMaria M, Jung JU, Desrosiers RC. Activation of lymphocyte signaling by the R1 protein of rhesus monkey rhadinovirus. J Virol. 2000 Mar; 74(6):2721-30.
    View in: PubMed
  92. Auerbach MR, Czajak SC, Johnson WE, Desrosiers RC, Alexander L. Species specificity of macaque rhadinovirus glycoprotein B sequences. J Virol. 2000 Jan; 74(1):584-90.
    View in: PubMed
  93. Mansfield KG, Westmoreland SV, DeBakker CD, Czajak S, Lackner AA, Desrosiers RC. Experimental infection of rhesus and pig-tailed macaques with macaque rhadinoviruses. J Virol. 1999 Dec; 73(12):10320-8.
    View in: PubMed
  94. Greenough TC, Brettler DB, Kirchhoff F, Alexander L, Desrosiers RC, O'Brien SJ, Somasundaran M, Luzuriaga K, Sullivan JL. Long-term nonprogressive infection with human immunodeficiency virus type 1 in a hemophilia cohort. J Infect Dis. 1999 Dec; 180(6):1790-802.
    View in: PubMed
  95. Wyand MS, Manson K, Montefiori DC, Lifson JD, Johnson RP, Desrosiers RC. Protection by live, attenuated simian immunodeficiency virus against heterologous challenge. J Virol. 1999 Oct; 73(10):8356-63.
    View in: PubMed
  96. Desrosiers RC. Strategies used by human immunodeficiency virus that allow persistent viral replication. Nat Med. 1999 Jul; 5(7):723-5.
    View in: PubMed
  97. Alexander L, Du Z, Howe AY, Czajak S, Desrosiers RC. Induction of AIDS in rhesus monkeys by a recombinant simian immunodeficiency virus expressing nef of human immunodeficiency virus type 1. J Virol. 1999 Jul; 73(7):5814-25.
    View in: PubMed
  98. Damania B, Li M, Choi JK, Alexander L, Jung JU, Desrosiers RC. Identification of the R1 oncogene and its protein product from the rhadinovirus of rhesus monkeys. J Virol. 1999 Jun; 73(6):5123-31.
    View in: PubMed
  99. Johnson RP, Lifson JD, Czajak SC, Cole KS, Manson KH, Glickman R, Yang J, Montefiori DC, Montelaro R, Wyand MS, Desrosiers RC. Highly attenuated vaccine strains of simian immunodeficiency virus protect against vaginal challenge: inverse relationship of degree of protection with level of attenuation. J Virol. 1999 Jun; 73(6):4952-61.
    View in: PubMed
  100. Glushakova S, Grivel JC, Suryanarayana K, Meylan P, Lifson JD, Desrosiers R, Margolis L. Nef enhances human immunodeficiency virus replication and responsiveness to interleukin-2 in human lymphoid tissue ex vivo. J Virol. 1999 May; 73(5):3968-74.
    View in: PubMed
  101. Li M, MacKey J, Czajak SC, Desrosiers RC, Lackner AA, Jung JU. Identification and characterization of Kaposi's sarcoma-associated herpesvirus K8.1 virion glycoprotein. J Virol. 1999 Feb; 73(2):1341-9.
    View in: PubMed
  102. Greenough TC, Sullivan JL, Desrosiers RC. Declining CD4 T-cell counts in a person infected with nef-deleted HIV-1. N Engl J Med. 1999 Jan 21; 340(3):236-7.
    View in: PubMed
  103. Alexander L, Veazey RS, Czajak S, DeMaria M, Rosenzweig M, Lackner AA, Desrosiers RC, Sasseville VG. Recombinant simian immunodeficiency virus expressing green fluorescent protein identifies infected cells in rhesus monkeys. AIDS Res Hum Retroviruses. 1999 Jan 1; 15(1):11-21.
    View in: PubMed
  104. Sasseville VG, Desrosiers RC, Morrison HG. Simian immunodeficiency viruses (Retroviridae). Encyclopedia of Virology. Webster R and Granoff A (eds.). 1999; 1640-1647.
  105. Howe AY, Jung JU, Desrosiers RC. Zeta chain of the T-cell receptor interacts with nef of simian immunodeficiency virus and human immunodeficiency virus type 2. J Virol. 1998 Dec; 72(12):9827-34.
    View in: PubMed
  106. Desrosiers RC. Will there be a live-attenuated HIV vaccine available for human safety trials by the year 2000? Interview by Gordon Nary. J Int Assoc Physicians AIDS Care. 1998 Nov; 4(11):22-3.
    View in: PubMed
  107. Robinson JE, Cole KS, Elliott DH, Lam H, Amedee AM, Means R, Desrosiers RC, Clements J, Montelaro RC, Murphey-Corb M. Production and characterization of SIV envelope-specific rhesus monoclonal antibodies from a macaque asymptomatically infected with a live SIV vaccine. AIDS Res Hum Retroviruses. 1998 Sep 20; 14(14):1253-62.
    View in: PubMed
  108. Desrosiers RC. Prospects for live attenuated HIV. Nat Med. 1998 Sep; 4(9):982.
    View in: PubMed
  109. Johnson RP, Desrosiers RC. Protective immunity induced by live attenuated simian immunodeficiency virus. Curr Opin Immunol. 1998 Aug; 10(4):436-43.
    View in: PubMed
  110. Duboise M, Guo J, Czajak S, Lee H, Veazey R, Desrosiers RC, Jung JU. A role for herpesvirus saimiri orf14 in transformation and persistent infection. J Virol. 1998 Aug; 72(8):6770-6.
    View in: PubMed
  111. Langlois AJ, Desrosiers RC, Lewis MG, KewalRamani VN, Littman DR, Zhou JY, Manson K, Wyand MS, Bolognesi DP, Montefiori DC. Neutralizing antibodies in sera from macaques immunized with attenuated simian immunodeficiency virus. J Virol. 1998 Aug; 72(8):6950-5.
    View in: PubMed
  112. Ilyinskii PO, Desrosiers RC. Identification of a sequence element immediately upstream of the polypurine tract that is essential for replication of simian immunodeficiency virus. EMBO J. 1998 Jul 1; 17(13):3766-74.
    View in: PubMed
  113. Reitter JN, Desrosiers RC. Identification of replication-competent strains of simian immunodeficiency virus lacking multiple attachment sites for N-linked carbohydrates in variable regions 1 and 2 of the surface envelope protein. J Virol. 1998 Jul; 72(7):5399-407.
    View in: PubMed
  114. Reitter JN, Means RE, Desrosiers RC. A role for carbohydrates in immune evasion in AIDS. Nat Med. 1998 Jun; 4(6):679-84.
    View in: PubMed
  115. Sasseville VG, Rottman JB, Du Z, Veazey R, Knight HL, Caunt D, Desrosiers RC, Lackner AA. Characterization of the cutaneous exanthem in macaques infected with a Nef gene variant of SIVmac239. J Invest Dermatol. 1998 Jun; 110(6):894-901.
    View in: PubMed
  116. Wykrzykowska JJ, Rosenzweig M, Veazey RS, Simon MA, Halvorsen K, Desrosiers RC, Johnson RP, Lackner AA. Early regeneration of thymic progenitors in rhesus macaques infected with simian immunodeficiency virus. J Exp Med. 1998 Jun 1; 187(11):1767-78.
    View in: PubMed
  117. Agosto M, Allan J, Benson C, Berger EA, Blumenthal R, Burton D, Clements J, Coffin J, Connor R, Cullen B, Desrosiers R, Dimitrov D, Doms R, Emerman M, Feinberg M, Fultz P, Gerard C, Gonsalves G, Haase A, Haigwood N, Hirsch V, Ho D, Hoxie JA, Hu SL, Zingale D, et al. AIDS vaccine development. Science. 1998 May 8; 280(5365):803, 804-5.
    View in: PubMed
  118. Veazey RS, DeMaria M, Chalifoux LV, Shvetz DE, Pauley DR, Knight HL, Rosenzweig M, Johnson RP, Desrosiers RC, Lackner AA. Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection. Science. 1998 Apr 17; 280(5362):427-31.
    View in: PubMed
  119. Lee H, Veazey R, Williams K, Li M, Guo J, Neipel F, Fleckenstein B, Lackner A, Desrosiers RC, Jung JU. Deregulation of cell growth by the K1 gene of Kaposi's sarcoma-associated herpesvirus. Nat Med. 1998 Apr; 4(4):435-40.
    View in: PubMed
  120. Duboise SM, Lee H, Guo J, Choi JK, Czajak S, Simon M, Desrosiers RC, Jung JU. Mutation of the Lck-binding motif of Tip enhances lymphoid cell activation by herpesvirus saimiri. J Virol. 1998 Apr; 72(4):2607-14.
    View in: PubMed
  121. Desrosiers R. Does the HIV-1deltakURNe vaccine strain hold the key to curbing HIV infection? An interview with Ronald Desrosiers, PhD. J Int Assoc Physicians AIDS Care. 1998 Mar; 4(3):45-6.
    View in: PubMed
  122. Desrosiers RC, Lifson JD, Gibbs JS, Czajak SC, Howe AY, Arthur LO, Johnson RP. Identification of highly attenuated mutants of simian immunodeficiency virus. J Virol. 1998 Feb; 72(2):1431-7.
    View in: PubMed
  123. Duboise SM, Guo J, Czajak S, Desrosiers RC, Jung JU. STP and Tip are essential for herpesvirus saimiri oncogenicity. J Virol. 1998 Feb; 72(2):1308-13.
    View in: PubMed
  124. Wooley DP, Smith RA, Czajak S, Desrosiers RC. Direct demonstration of retroviral recombination in a rhesus monkey. J Virol. 1997 Dec; 71(12):9650-3.
    View in: PubMed
  125. Desrosiers RC, Sasseville VG, Czajak SC, Zhang X, Mansfield KG, Kaur A, Johnson RP, Lackner AA, Jung JU. A herpesvirus of rhesus monkeys related to the human Kaposi's sarcoma-associated herpesvirus. J Virol. 1997 Dec; 71(12):9764-9.
    View in: PubMed
  126. Shibata R, Siemon C, Czajak SC, Desrosiers RC, Martin MA. Live, attenuated simian immunodeficiency virus vaccines elicit potent resistance against a challenge with a human immunodeficiency virus type 1 chimeric virus. J Virol. 1997 Nov; 71(11):8141-8.
    View in: PubMed
  127. Du Z, Ilyinskii PO, Lally K, Desrosiers RC, Engelman A. A mutation in integrase can compensate for mutations in the simian immunodeficiency virus att site. J Virol. 1997 Nov; 71(11):8124-32.
    View in: PubMed
  128. Johnson RP, Glickman RL, Yang JQ, Kaur A, Dion JT, Mulligan MJ, Desrosiers RC. Induction of vigorous cytotoxic T-lymphocyte responses by live attenuated simian immunodeficiency virus. J Virol. 1997 Oct; 71(10):7711-8.
    View in: PubMed
  129. Means RE, Greenough T, Desrosiers RC. Neutralization sensitivity of cell culture-passaged simian immunodeficiency virus. J Virol. 1997 Oct; 71(10):7895-902.
    View in: PubMed
  130. Alexander L, Du Z, Rosenzweig M, Jung JU, Desrosiers RC. A role for natural simian immunodeficiency virus and human immunodeficiency virus type 1 nef alleles in lymphocyte activation. J Virol. 1997 Aug; 71(8):6094-9.
    View in: PubMed
  131. Cole KS, Rowles JL, Jagerski BA, Murphey-Corb M, Unangst T, Clements JE, Robinson J, Wyand MS, Desrosiers RC, Montelaro RC. Evolution of envelope-specific antibody responses in monkeys experimentally infected or immunized with simian immunodeficiency virus and its association with the development of protective immunity. J Virol. 1997 Jul; 71(7):5069-79.
    View in: PubMed
  132. Alexander L, Lee H, Rosenzweig M, Jung JU, Desrosiers RC. EGFP-containing vector system that facilitates stable and transient expression assays. Biotechniques. 1997 Jul; 23(1):64-6.
    View in: PubMed
  133. Kirchhoff F, Greenough TC, Hamacher M, Sullivan JL, Desrosiers RC. Activity of human immunodeficiency virus type 1 promoter/TAR regions and tat1 genes derived from individuals with different rates of disease progression. Virology. 1997 Jun 9; 232(2):319-31.
    View in: PubMed
  134. Lee H, Trimble JJ, Yoon DW, Regier D, Desrosiers RC, Jung JU. Genetic variation of herpesvirus saimiri subgroup A transforming protein and its association with cellular src. J Virol. 1997 May; 71(5):3817-25.
    View in: PubMed
  135. Giri A, Slattery JP, Heneine W, Gessain A, Rivadeneira E, Desrosiers RC, Rosen L, Anthony R, Pamungkas J, Iskandriati D, Richards AL, Herve V, McClure H, O'Brien SJ, Franchini G. The tax gene sequences form two divergent monophyletic lineages corresponding to types I and II of simian and human T-cell leukemia/lymphotropic viruses. Virology. 1997 Apr 28; 231(1):96-104.
    View in: PubMed
  136. Ilyinskii PO, Simon MA, Czajak SC, Lackner AA, Desrosiers RC. Induction of AIDS by simian immunodeficiency virus lacking NF-kappaB and SP1 binding elements. J Virol. 1997 Mar; 71(3):1880-7.
    View in: PubMed
  137. Zou W, Lackner AA, Simon M, Durand-Gasselin I, Galanaud P, Desrosiers RC, Emilie D. Early cytokine and chemokine gene expression in lymph nodes of macaques infected with simian immunodeficiency virus is predictive of disease outcome and vaccine efficacy. J Virol. 1997 Feb; 71(2):1227-36.
    View in: PubMed
  138. Desrosiers RC. Approaches to AIDS research. Science. 1997 Jan 3; 275(5296):13.
    View in: PubMed
  139. Wyand MS, Manson KH, Lackner AA, Desrosiers RC. Resistance of neonatal monkeys to live attenuated vaccine strains of simian immunodeficiency virus. Nat Med. 1997 Jan; 3(1):32-6.
    View in: PubMed
  140. Desrosiers RC. The value of specific pathogen-free rhesus monkey breeding colonies for AIDS research. AIDS Res Hum Retroviruses. 1997 Jan 1; 13(1):5-6.
    View in: PubMed
  141. Means RE, Reitter J and Desrosiers RC. N-glycosylation and the avoidance of humoral immunity. Colloque Des Cent Gardes. Girard M and Dodet B (eds.). 1997; 11:137-43.
  142. Fauci AS and Desrosiers. pathogenesis of HIV and SIV. Retroviruses. Coffin JM, Hughes SH and Varmus HE (eds.). 1997; 587-635.
  143. Mariani R, Kirchhoff F, Greenough TC, Sullivan JL, Desrosiers RC, Skowronski J. High frequency of defective nef alleles in a long-term survivor with nonprogressive human immunodeficiency virus type 1 infection. J Virol. 1996 Nov; 70(11):7752-64.
    View in: PubMed
  144. Duboise SM, Guo J, Desrosiers RC, Jung JU. Use of virion DNA as a cloning vector for the construction of mutant and recombinant herpesviruses. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11389-94.
    View in: PubMed
  145. Sasseville VG, Pauley DR, Young HL, MacKey JJ, Simon MA, Desrosiers RC, Lackner AA. A case of pulmonary cestodiasis in a simian immunodeficiency virus-infected pigtailed macaque (Macaca nemestrina) in which virus-infected leukocytes are present within the lesion. J Med Primatol. 1996 Aug; 25(4):251-6.
    View in: PubMed
  146. Sasseville VG, Du Z, Chalifoux LV, Pauley DR, Young HL, Sehgal PK, Desrosiers RC, Lackner AA. Induction of lymphocyte proliferation and severe gastrointestinal disease in macaques by a nef gene variant SIVmac239. Am J Pathol. 1996 Jul; 149(1):163-76.
    View in: PubMed
  147. Du Z, Ilyinskii PO, Sasseville VG, Newstein M, Lackner AA, Desrosiers RC. Requirements for lymphocyte activation by unusual strains of simian immunodeficiency virus. J Virol. 1996 Jun; 70(6):4157-61.
    View in: PubMed
  148. Wyand MS, Manson KH, Garcia-Moll M, Montefiori D, Desrosiers RC. Vaccine protection by a triple deletion mutant of simian immunodeficiency virus. J Virol. 1996 Jun; 70(6):3724-33.
    View in: PubMed
  149. Giorgi JV, Hultin LE, Desrosiers RC. The immunopathogenesis of retroviral diseases: no immunophenotypic alterations in T, B, and NK cell subsets in SIVmac239-challenged rhesus macaques protected by SIV delta nef vaccination. J Med Primatol. 1996 Jun; 25(3):186-91.
    View in: PubMed
  150. Ilyinskii PO, Desrosiers RC. Efficient transcription and replication of simian immunodeficiency virus in the absence of NF-kappaB and Sp1 binding elements. J Virol. 1996 May; 70(5):3118-26.
    View in: PubMed
  151. Kirchhoff F, Desrosiers RC. Random mutagenesis of short target DNA sequences via PCR with degenerate oligonucleotides. Methods Mol Biol. 1996; 57:323-33.
    View in: PubMed
  152. Lang SM, Desrosiers RC. Relative importance and functional role of genetic elements targeted for a live attenuated AIDS vaccine. Antibiot Chemother. 1996; 48:92-9.
    View in: PubMed
  153. Jung JU, Desrosiers RC. Association of the viral oncoprotein STP-C488 with cellular ras. Mol Cell Biol. 1995 Dec; 15(12):6506-12.
    View in: PubMed
  154. Jung JU, Lang SM, Jun T, Roberts TM, Veillette A, Desrosiers RC. Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiri. J Virol. 1995 Dec; 69(12):7814-22.
    View in: PubMed
  155. Kirchhoff F, Morrison HG, Desrosiers RC. Identification of V3 mutations that can compensate for inactivating mutations in C4 of simian immunodeficiency virus. Virology. 1995 Oct 20; 213(1):179-89.
    View in: PubMed
  156. Jung JU, Lang SM, Friedrich U, Jun T, Roberts TM, Desrosiers RC, Biesinger B. Identification of Lck-binding elements in tip of herpesvirus saimiri. J Biol Chem. 1995 Sep 1; 270(35):20660-7.
    View in: PubMed
  157. Du Z, Lang SM, Sasseville VG, Lackner AA, Ilyinskii PO, Daniel MD, Jung JU, Desrosiers RC. Identification of a nef allele that causes lymphocyte activation and acute disease in macaque monkeys. Cell. 1995 Aug 25; 82(4):665-74.
    View in: PubMed
  158. Morrison HG, Kirchhoff F, Desrosiers RC. Effects of mutations in constant regions 3 and 4 of envelope of simian immunodeficiency virus. Virology. 1995 Jul 10; 210(2):448-55.
    View in: PubMed
  159. Gibbs JS, Lackner AA, Lang SM, Simon MA, Sehgal PK, Daniel MD, Desrosiers RC. Progression to AIDS in the absence of a gene for vpr or vpx. J Virol. 1995 Apr; 69(4):2378-83.
    View in: PubMed
  160. Du Z, Regier DA, Desrosiers RC. Improved recombinant PCR mutagenesis procedure that uses alkaline-denatured plasmid template. Biotechniques. 1995 Mar; 18(3):376-8.
    View in: PubMed
  161. Kirchhoff F, Greenough TC, Brettler DB, Sullivan JL, Desrosiers RC. Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection. N Engl J Med. 1995 Jan 26; 332(4):228-32.
    View in: PubMed
  162. Du Z, Lang SM, Sasseville VG, Lackner AA, Ilyinskii PO, Daniel MD, Jung JU, Desrosiers RC. A role for nef in signal transduction and lymphocyte activation. Dixieme Colloque Des Cent Gardes. 1995; 45-47.
  163. Desrosiers RC. Non-human primate models for AIDS vaccines. AIDS. 1995; 9 Suppl A:S137-41.
    View in: PubMed
  164. Desrosiers RC. Problems and issues facing development of a preventive vaccine for AIDS: lessons from Pasteur. The Year of Louis Pasteur International Symposia. 1995; 127-29.
  165. Du Z, Lang SM, Sasseville VG, Lackner AA, Ilyinskii PO, Daniel MD, Jung JU, Desrosiers RC. A role for nef in signal transduction and lymphocyte activation. Dixieme Colloque Des Cent Gardes. 1995; 45-47.
  166. Lang SM and Desrosiers RC. Relative importance and functional role of genetic elements targeted for a live attenuated AIDS vaccine. Development and Applications of Vaccines and Gene Therapy in AIDS. Antibiot Chemother. Giraldo G, Bolognesi DP, Salvatore M, Beth-Giraldo E, Schonfeld H. 1995; 48:92-99.
  167. Desrosiers RC, Daniel MD, Lifson J, Arthur LO. Infection of chimpanzees with attenuated HIV-1 deletion mutants. Dixieme Colloque Des Gardes. 1995; 197-200.
  168. Jin MJ, Rogers J, Phillips-Conroy JE, Allan JS, Desrosiers RC, Shaw GM, Sharp PM, Hahn BH. Infection of a yellow baboon with simian immunodeficiency virus from African green monkeys: evidence for cross-species transmission in the wild. J Virol. 1994 Dec; 68(12):8454-60.
    View in: PubMed
  169. Jung JU, Desrosiers RC. Distinct functional domains of STP-C488 of herpesvirus saimiri. Virology. 1994 Nov 1; 204(2):751-8.
    View in: PubMed
  170. Jung JU, Stäger M, Desrosiers RC. Virus-encoded cyclin. Mol Cell Biol. 1994 Nov; 14(11):7235-44.
    View in: PubMed
  171. Ilyinskii PO, Daniel MD, Simon MA, Lackner AA, Desrosiers RC. The role of upstream U3 sequences in the pathogenesis of simian immunodeficiency virus-induced AIDS in rhesus monkeys. J Virol. 1994 Sep; 68(9):5933-44.
    View in: PubMed
  172. Choi WS, Collignon C, Thiriart C, Burns DP, Stott EJ, Kent KA, Desrosiers RC. Effects of natural sequence variation on recognition by monoclonal antibodies neutralize simian immunodeficiency virus infectivity. J Virol. 1994 Sep; 68(9):5395-402.
    View in: PubMed
  173. Daniel MD, Mazzara GP, Simon MA, Sehgal PK, Kodama T, Panicali DL, Desrosiers RC. High-titer immune responses elicited by recombinant vaccinia virus priming and particle boosting are ineffective in preventing virulent SIV infection. AIDS Res Hum Retroviruses. 1994 Jul; 10(7):839-51.
    View in: PubMed
  174. Kirchhoff F, Mori K, Desrosiers RC. The "V3" domain is a determinant of simian immunodeficiency virus cell tropism. J Virol. 1994 Jun; 68(6):3682-92.
    View in: PubMed
  175. Simon MA, Brodie SJ, Sasseville VG, Chalifoux LV, Desrosiers RC, Ringler DJ. Immunopathogenesis of SIVmac. Virus Res. 1994 May; 32(2):227-51.
    View in: PubMed
  176. Gibbs JS, Regier DA, Desrosiers RC. Construction and in vitro properties of SIVmac mutants with deletions in "nonessential" genes. AIDS Res Hum Retroviruses. 1994 May; 10(5):607-16.
    View in: PubMed
  177. Gibbs JS, Regier DA, Desrosiers RC. Construction and in vitro properties of HIV-1 mutants with deletions in "nonessential" genes. AIDS Res Hum Retroviruses. 1994 Apr; 10(4):343-50.
    View in: PubMed
  178. Gibbs JS, Regier DA, Desrosiers RC. Construction and in vitro properties of SIVmac mutants with deletions in "nonessential" genes. AIDS Res Hum Retroviruses. 1994 Apr; 10(4):333-42.
    View in: PubMed
  179. Desrosiers RC. Safety issues facing development of a live-attenuated, multiply deleted HIV-1 vaccine. AIDS Res Hum Retroviruses. 1994 Apr; 10(4):331-2.
    View in: PubMed
  180. Kirchhoff F, Kestler HW, Desrosiers RC. Upstream U3 sequences in simian immunodeficiency virus are selectively deleted in vivo in the absence of an intact nef gene. J Virol. 1994 Mar; 68(3):2031-7.
    View in: PubMed
  181. Kirchhoff F, Morrison HG, Murray MG, Rennert P, Desrosiers RC. SIVmac expressing hybrid envelope proteins containing HIV-1 V3 and/or C4 sequences is not competent for replication. AIDS Res Hum Retroviruses. 1994 Mar; 10(3):309-13.
    View in: PubMed
  182. Lewis MG, Bellah S, McKinnon K, Yalley-Ogunro J, Zack PM, Elkins WR, Desrosiers RC, Eddy GA. Titration and characterization of two rhesus-derived SIVmac challenge stocks. AIDS Res Hum Retroviruses. 1994 Feb; 10(2):213-20.
    View in: PubMed
  183. Hunt RD, Desrosiers RC. Study of spontaneous infectious diseases of primates: Contribution of the Regional Primate Research Centers programs to conservation and new scientific opportunities. Am J Primatol. 1994; (34):3-10.
  184. Jung JU and Desrosiers RC. Herpesviruses saimiri and ateles. Encyclopedia of Virology. Webster R and Granoff A (eds.). 1994; 614-22.
  185. Balayan M et al (World Health Organization Working Group). Feasibility of developing live attenuated HIV vaccines: conclusions and recommendations. AIDS res Hum Retroviruses. 1994; (10):221-22.
  186. Murphy C, Kretschmer C, Biesinger B, Beckers J, Jung J, Desrosiers RC, Müller-Hermelink HK, Fleckenstein BW, Rüther U. Epithelial tumours induced by a herpesvirus oncogene in transgenic mice. Oncogene. 1994 Jan; 9(1):221-6.
    View in: PubMed
  187. Burns DP, Desrosiers RC. Envelope sequence variation, neutralizing antibodies, and primate lentivirus persistence. Curr Top Microbiol Immunol. 1994; 188:185-219.
    View in: PubMed
  188. Letvin NL and Desrosiers RC. Simian Immunodeficiency Virus. 1994.
  189. Grassmann R, Fleckenstein B, Desrosiers RC. Viral transformation of human T lymphocytes. Adv Cancer Res. 1994; 63:211-44.
    View in: PubMed
  190. Morrison HG and Desrosiers RC. Simian immunodeficiency viruses. Encyclopedia of Virology. Webster R and Granoff A (eds.). 1994; 614-21.
  191. Phillips-Conroy JE, Jolly CJ, Petros B, Allan JS, Desrosiers RC. Sexual transmission of SIVagm in wild grivet monkeys. J Med Primatol. 1994 Jan; 23(1):1-7.
    View in: PubMed
  192. Kodama T, Mori K, Kawahara T, Ringler DJ, Desrosiers RC. Analysis of simian immunodeficiency virus sequence variation in tissues of rhesus macaques with simian AIDS. J Virol. 1993 Nov; 67(11):6522-34.
    View in: PubMed
  193. Berend KR, Jung JU, Boyle TJ, DiMaio JM, Mungal SA, Desrosiers RC, Lyerly HK. Phenotypic and functional consequences of herpesvirus saimiri infection of human CD8+ cytotoxic T lymphocytes. J Virol. 1993 Oct; 67(10):6317-21.
    View in: PubMed
  194. Burns DP, Collignon C, Desrosiers RC. Simian immunodeficiency virus mutants resistant to serum neutralization arise during persistent infection of rhesus monkeys. J Virol. 1993 Jul; 67(7):4104-13.
    View in: PubMed
  195. Morrison HG, Kirchhoff F, Desrosiers RC. Evidence for the cooperation of gp120 amino acids 322 and 448 in SIVmac entry. Virology. 1993 Jul; 195(1):167-74.
    View in: PubMed
  196. Nathanson N, McGann KA, Wilesmith J, Desrosiers RC, Brookmeyer R. The evolution of virus diseases: their emergence, epidemicity, and control. Virus Res. 1993 Jul; 29(1):3-20.
    View in: PubMed
  197. Mori K, Ringler DJ, Desrosiers RC. Restricted replication of simian immunodeficiency virus strain 239 in macrophages is determined by env but is not due to restricted entry. J Virol. 1993 May; 67(5):2807-14.
    View in: PubMed
  198. Kirchhoff F, Desrosiers RC. A PCR-derived library of random point mutations within the V3 region of simian immunodeficiency virus. PCR Methods Appl. 1993 May; 2(4):301-4.
    View in: PubMed
  199. Morrison HG, Desrosiers RC. A PCR-based strategy for extensive mutagenesis of a target DNA sequence. Biotechniques. 1993 Mar; 14(3):454-7.
    View in: PubMed
  200. Fickenscher H, Grassman R, Biesinger B, Ramstedt U, Haseltine WA, Desrosiers RC, Fleckenstein B. Viral genes involved in stable growth transformation of human T-lymphocytes. Virus Strategies Molecular Biology and Pathogenesis. Doerfler W and Bohm P (eds.). 1993; 401-06.
  201. Desrosiers RC and Ringler DJ. Viral determinants of neurological disease in AIDS. Discussions in Neuroscience: Molecular and Cellular Mechanisms of Neural-Immune Interactions. Wiesel T, Anderson D and Katz L (eds.). 1993; IX(3+4):52-55.
  202. D'Souza MP, Kent KA, Thiriart C, Collignon C, Milman G and Collaborating Investigators. International collaboration comparing neutralization and binding assays for monoclonal anataibodies to simian immunodeficiency virus. AIDS Res Hum Retroviruses. 1993; (9):415-422.
  203. Biesinger B, Grassmann R, Haseltine WA, Desroseirs RC, Fleckenstein B. Virus-induced growth transformation of human T-lymphocytes. Concepts in Virology from Ivanovsky to the Present. Mahy BWJ and Lvov DK (eds.). 1993; 351-55.
  204. Desrosiers RC, Daniel MD, Wyand MS, Arthur LO. A radical strategy for development of a vaccine against HIV-1. Retroviruses of Human AIDS and Related Animal Diseases. Girard M and Valette L (eds.). 1993; 205-209.
  205. Cranage MP, Polyanskaya N, McBride B, Cook N, Ashworth LAE, Dennis M, Baskerville A, Greenaway PJ, Corcoran T, Kitchin P, Rose J, Murphey-Corb M, Desrosiers RC, Stott EJ, Farrar GH. Studies on the specificity of the vaccine effect elicited by inactivated simian immunodeficiency virus. AIDS Res Hum Retroviruses. 1993; (9):13-22.
  206. Gibbs JS and Desrosiers RC. Auxiliary proteins of primate immunodeficiency viruses. Human Retroviruses: Frontiers in Moleuclar Biology. Cullen, BR (ed.). 1993; Chapter 6:137-58.
  207. Daniel MD, Kirchhoff F, Czajak SC, Sehgal PK, Desrosiers RC. Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. Science. 1992 Dec 18; 258(5090):1938-41.
    View in: PubMed
  208. Ilyinskii PO, Daniel MD, Horvath CJ, Desrosiers RC. Genetic analysis of simian virus 40 from brains and kidneys of macaque monkeys. J Virol. 1992 Nov; 66(11):6353-60.
    View in: PubMed
  209. Panicali DL, Mazzara G, Sullivan JL, Hesselton R, Shen L, Letvin N, Daniel M, Desrosiers R, Stott EJ. Use of lentivirus-like particles alone and in combination with live vaccinia-virus-based vaccines. AIDS Res Hum Retroviruses. 1992 Aug; 8(8):1449.
    View in: PubMed
  210. Desrosiers RC. HIV with multiple gene deletions as a live attenuated vaccine for AIDS. AIDS Res Hum Retroviruses. 1992 Aug; 8(8):1457.
    View in: PubMed
  211. McEntee MF, Anderson MG, Daniel MD, Adams R, Farzadegan H, Desrosiers RC, Narayan O. Differences in neutralization of simian lentivirus (SIVMAC) in lymphocyte and macrophage cultures. AIDS Res Hum Retroviruses. 1992 Jun; 8(6):1193-8.
    View in: PubMed
  212. Burns DP, Desrosiers RC. A caution on the use of SIV/HIV gag antigen detection systems in neutralization assays. AIDS Res Hum Retroviruses. 1992 Jun; 8(6):1189-92.
    View in: PubMed
  213. Biesinger B, Müller-Fleckenstein I, Simmer B, Lang G, Wittmann S, Platzer E, Desrosiers RC, Fleckenstein B. Stable growth transformation of human T lymphocytes by herpesvirus saimiri. Proc Natl Acad Sci U S A. 1992 Apr 1; 89(7):3116-9.
    View in: PubMed
  214. Mori K, Ringler DJ, Kodama T, Desrosiers RC. Complex determinants of macrophage tropism in env of simian immunodeficiency virus. J Virol. 1992 Apr; 66(4):2067-75.
    View in: PubMed
  215. Jung JU, Desrosiers RC. Herpesvirus saimiri oncogene STP-C488 encodes a phosphoprotein. J Virol. 1992 Mar; 66(3):1777-80.
    View in: PubMed
  216. Desrosiers RC. Inching towards a vaccine for AIDS. Curr Biol. 1992 Mar; 2(3):162-3.
    View in: PubMed
  217. Desrosiers RC. HIV with multiple gene deletions as a live attenuated vaccine for AIDS. AIDS Res Hum Retroviruses. 1992 Mar; 8(3):411-21.
    View in: PubMed
  218. Cranage MP, Ashworth LA, Greenaway PJ, Murphey-Corb M, Desrosiers RC. AIDS vaccine developments. Nature. 1992 Feb 20; 355(6362):685-6.
    View in: PubMed
  219. Javaherian K, Langlois AJ, Schmidt S, Kaufmann M, Cates N, Langedijk JP, Meloen RH, Desrosiers RC, Burns DP, Bolognesi DP, et al. The principal neutralization determinant of simian immunodeficiency virus differs from that of human immunodeficiency virus type 1. Proc Natl Acad Sci U S A. 1992 Feb 15; 89(4):1418-22.
    View in: PubMed
  220. Roizmann B, Desrosiers RC, Fleckenstein B, Lopez C, Minson AC, Studdert MJ. The family Herpesviridae: an update. The Herpesvirus Study Group of the International Committee on Taxonomy of Viruses. Arch Virol. 1992; 123(3-4):425-49.
    View in: PubMed
  221. Jung JU, Desrosiers RC. Identification and characterization of the herpesvirus saimiri oncoprotein STP-C488. J Virol. 1991 Dec; 65(12):6953-60.
    View in: PubMed
  222. Walsh DG, Horvath CJ, Hansen-Moosa A, MacKey JJ, Sehgal PK, Daniel MD, Desrosiers RC, Ringler DJ. Cytokine influence on simian immunodeficiency virus replication within primary macrophages. TNF-alpha, but not GMCSF, enhances viral replication on a per-cell basis. Am J Pathol. 1991 Oct; 139(4):877-87.
    View in: PubMed
  223. Horvath CJ, Desrosiers RC, Sehgal PK, King NW, Ringler DJ. Effect of simian immunodeficiency virus infection on tumor necrosis factor-alpha production by alveolar macrophages. Lab Invest. 1991 Sep; 65(3):280-6.
    View in: PubMed
  224. Jung JU, Trimble JJ, King NW, Biesinger B, Fleckenstein BW, Desrosiers RC. Identification of transforming genes of subgroup A and C strains of Herpesvirus saimiri. Proc Natl Acad Sci U S A. 1991 Aug 15; 88(16):7051-5.
    View in: PubMed
  225. Desrosiers RC, Hansen-Moosa A, Mori K, Bouvier DP, King NW, Daniel MD, Ringler DJ. Macrophage-tropic variants of SIV are associated with specific AIDS-related lesions but are not essential for the development of AIDS. Am J Pathol. 1991 Jul; 139(1):29-35.
    View in: PubMed
  226. Desrosiers RC, Hunter E. AIDS biosafety. Science. 1991 May 31; 252(5010):1231.
    View in: PubMed
  227. Kestler HW, Ringler DJ, Mori K, Panicali DL, Sehgal PK, Daniel MD, Desrosiers RC. Importance of the nef gene for maintenance of high virus loads and for development of AIDS. Cell. 1991 May 17; 65(4):651-62.
    View in: PubMed
  228. Burns DP, Desrosiers RC. Selection of genetic variants of simian immunodeficiency virus in persistently infected rhesus monkeys. J Virol. 1991 Apr; 65(4):1843-54.
    View in: PubMed
  229. Kodama T, Burns DP, Silva DP, Veronese FD, Desrosiers RC. Strain-specific neutralizing determinant in the transmembrane protein of simian immunodeficiency virus. J Virol. 1991 Apr; 65(4):2010-8.
    View in: PubMed
  230. Hosmalin A, Nara PL, Zweig M, Lerche NW, Cease KB, Gard EA, Markham PD, Putney SD, Daniel MD, Desrosiers RC, et al. Priming with T helper cell epitope peptides enhances the antibody response to the envelope glycoprotein of HIV-1 in primates. J Immunol. 1991 Mar 1; 146(5):1667-73.
    View in: PubMed
  231. Ilyinskii P, Daniel M, Lerche N, Desrosiers R. Antibodies to type D retrovirus in talapoin monkeys. J Gen Virol. 1991 Feb; 72 ( Pt 2):453-6.
    View in: PubMed
  232. Li Y, Steen R, Butler C, FultzP, Marx P and Desrosiers R. Genetic analysis of simian immunodeficiency viruses and their relationship to human immunodeficiency viruses. Proceedings of 4th Iternational Congress of Systematic and Evolutionary Biology. 1991; 424-29.
  233. Marx PA, Li Y, Lerche NW, Sutjipto S, Gettie A, Yee JA, Brotman BH, Prince AM, Hanson A, Webster RG, Desrosiers RC. Simian immunodeficiency virus related to human immunodeficiency virus type 2 from a west African pet sooty mangabey. J Virol. 1991; (65):4480-85.
  234. Trimble JJ, Desrosiers RC. Transformation by herpesvirus saimiri. Adv Cancer Res. 1991; 56:335-55.
    View in: PubMed
  235. Trimble JJ, Regier DA, Desrosiers RC. Herpesvirus saimiri U RNA sequence variation. Nucleic Acids Res. 1990 Nov 11; 18(21):6456.
    View in: PubMed
  236. Regier DA, Desrosiers RC. The complete nucleotide sequence of a pathogenic molecular clone of simian immunodeficiency virus. AIDS Res Hum Retroviruses. 1990 Nov; 6(11):1221-31.
    View in: PubMed
  237. Montefiori DC, Murphey-Corb M, Desrosiers RC, Daniel MD. Complement-mediated, infection-enhancing antibodies in plasma from vaccinated macaques before and after inoculation with live simian immunodeficiency virus. J Virol. 1990 Oct; 64(10):5223-5.
    View in: PubMed
  238. Biesinger B, Trimble JJ, Desrosiers RC, Fleckenstein B. The divergence between two oncogenic Herpesvirus saimiri strains in a genomic region related to the transforming phenotype. Virology. 1990 Jun; 176(2):505-14.
    View in: PubMed
  239. Desrosiers RC. HIV-1 origins. A finger on the missing link. Nature. 1990 May 24; 345(6273):288-9.
    View in: PubMed
  240. Ringler DJ, Walsh DG, Chalifoux LV, MacKey JJ, Daniel MD, Desrosiers RC, King NW, Hancock WW. Soluble and membrane-associated interleukin 2 receptor-alpha expression in rhesus monkeys infected with simian immunodeficiency virus. Lab Invest. 1990 Apr; 62(4):435-43.
    View in: PubMed
  241. Desrosiers RC. The simian immunodeficiency viruses. Annu Rev Immunol. 1990; 8:557-78.
    View in: PubMed
  242. Kodama T, Burns DP, Kestler HW, Daniel MD, Desrosiers RC. Molecular changes associated with replication of simian immunodeficiency virus in human cells. J Med Primatol. 1990; 19(3-4):431-7.
    View in: PubMed
  243. Kestler HW, Mori K, Silva DP, Kodama T, King NW, Daniel MD, Desrosiers RC. Nef genes of SIV. J Med Primatol. 1990; 19(3-4):421-9.
    View in: PubMed
  244. Desrosiers RC, Li Y, Daniel MD. Use of simian immunodeficiency virus for AIDS vaccine research. AIDS Vaccine Research and Clinical Trials. Putney SD and Bolognesi DP (eds). 1990; 361-67.
  245. Daniel MD, Sehgal PK, Kodama T, Wyand MS, Ringler DJ, King NW, Schmidt DK, Troup CD, Desrosiers RC. Use of simian immunodeficiency virus for vaccine research. J Med Primatol. 1990; 19(3-4):395-9.
    View in: PubMed
  246. Kodama T, Kestler HW, Burns DP, Ringler DJ, King NW, Daniel MD, Desrosiers RC. Nonhuman primate lentiviruses: models for human infection. Dev Biol Stand. 1990; 72:267-71.
    View in: PubMed
  247. Sutjipto S, Kodama T, Yee J, Gettie A, Jennings M, Desrosiers RC, Marx PA. Characterization of monoclonal antibodies that distinguish simian immunodeficiency virus isolates from each other and from human immunodeficiency virus types 1 and 2. J Gen Virol. 1990 Jan; 71 ( Pt 1):247-9.
    View in: PubMed
  248. Burns DP, Desrosiers RC. Sequence variability of simian immunodeficiency virus in a persistently infected rhesus monkey. J Med Primatol. 1990; 19(3-4):317-26.
    View in: PubMed
  249. Kestler H, Kodama T, Ringler D, Marthas M, Pedersen N, Lackner A, Regier D, Sehgal P, Daniel M, King N, Desrosiers R. Induction of AIDS in rhesus monkeys by molecularly cloned simian immunodeficiency virus. Science. 1990; (248):1109-12.
  250. King NW, Chalifoux LV, Ringler DJ, Wyand MS, Sehgal PK, Daniel MD, Letvin NL, Desrosiers RC, Blake BJ, Hunt RD. Comparative biology of natural and experimental SIVmac infection in macaque monkeys: a review. J Med Primatol. 1990; 19(2):109-18.
    View in: PubMed
  251. Burns DPW, Kodama T, Mori K, Kestler HW, Morrison HG, Gibbs JS, Ringler DJ, Daniel MD, Desrosiers RC. Use of cloned SIVmac of defined sequence for the study of AIDS pathogenesis. SIV vaccine studies in rhesus monkeys. Retroviruses of Human A.I.D.S. and Related Animal Diseases. Girard M and Valette L (eds). 1990; 47-52.
  252. Desrosiers RC. Virus purification, preparation of infectious virus stock, and virus storage. Techniques in HIV Research. Aldovini A and Walker BD (eds). 1990; 121-27.
  253. Kodama T, Wooley DP, Naidu YM, Kestler HW, Daniel MD, Li Y, Desrosiers RC. Significance of premature stop codons in env of simian immunodeficiency virus. J Virol. 1989 Nov; 63(11):4709-14.
    View in: PubMed
  254. Desrosiers RC, Daniel MD, Li Y. HIV-related lentiviruses of nonhuman primates. AIDS Res Hum Retroviruses. 1989 Oct; 5(5):465-73.
    View in: PubMed
  255. Desrosiers R, Tanguay RM. Transcriptional inhibitors affecting topoisomerase II induce changes in histone methylation patterns similar to those induced by heat shock. Biochem Biophys Res Commun. 1989 Aug 15; 162(3):1037-43.
    View in: PubMed
  256. Murthy SC, Trimble JJ, Desrosiers RC. Deletion mutants of herpesvirus saimiri define an open reading frame necessary for transformation. J Virol. 1989 Aug; 63(8):3307-14.
    View in: PubMed
  257. Desrosiers RC, Wyand MS, Kodama T, Ringler DJ, Arthur LO, Sehgal PK, Letvin NL, King NW, Daniel MD. Vaccine protection against simian immunodeficiency virus infection. Proc Natl Acad Sci U S A. 1989 Aug; 86(16):6353-7.
    View in: PubMed
  258. Kodama T, Silva DP, Daniel MD, Phillips-Conroy JE, Jolly CJ, Rogers J, Desrosiers RC. Prevalence of antibodies to SIV in baboons in their native habitat. AIDS Res Hum Retroviruses. 1989 Jun; 5(3):337-43.
    View in: PubMed
  259. Li Y, Naidu YM, Daniel MD, Desrosiers RC. Extensive genetic variability of simian immunodeficiency virus from African green monkeys. J Virol. 1989 Apr; 63(4):1800-2.
    View in: PubMed
  260. Ringler DJ, Wyand MS, Walsh DG, MacKey JJ, Chalifoux LV, Popovic M, Minassian AA, Sehgal PK, Daniel MD, Desrosiers RC, et al. Cellular localization of simian immunodeficiency virus in lymphoid tissues. I. Immunohistochemistry and electron microscopy. Am J Pathol. 1989 Feb; 134(2):373-83.
    View in: PubMed
  261. Wyand MS, Ringler DJ, Naidu YM, Mattmuller M, Chalifoux LV, Sehgal PK, Daniel MD, Desrosiers RC, King NW. Cellular localization of simian immunodeficiency virus in lymphoid tissues. II. In situ hybridization. Am J Pathol. 1989 Feb; 134(2):385-93.
    View in: PubMed
  262. Ringler DJ, Wyand MS, Walsh DG, MacKey JJ, Sehgal PK, Daniel MD, Desrosiers RC, King NW. The productive infection of alveolar macrophages by simian immunodeficiency virus. J Med Primatol. 1989; 18(3-4):217-26.
    View in: PubMed
  263. Li Y, Naidu Y, Fultz P, Daniel MD, Desrosiers RC. Genetic diversity of simian immunodeficiency virus. J Med Primatol. 1989; 18(3-4):261-9.
    View in: PubMed
  264. Kestler HW, Naidu YN, Kodama T, King NW, Daniel MD, Li Y, Desrosiers RC. Use of infectious molecular clones of simian immunodeficiency virus for pathogenesis studies. J Med Primatol. 1989; 18(3-4):305-9.
    View in: PubMed
  265. Desrosiers RC, Ringler DJ. Use of simian immunodeficiency viruses for AIDS research. Intervirology. 1989; 30(6):301-12.
    View in: PubMed
  266. Biesinger B, Grassmann R, Fleckenstein B, Murthy SC, Trimble J, Desrosiers RC. Genes for the synthesis of deoxythymidylate monophosphate in T-cell lymphoma-inducing herpesviruses of nonhuman primates. Curr Top Microbiol Immunol. 1989; 144:241-7.
    View in: PubMed
  267. Daniel MD, Desrosiers RC. Use of simian immunodeficiency virus for evaluation of AIDS vaccine strategies. AIDS. 1989; 3 Suppl 1:S131-3.
    View in: PubMed
  268. Kestler HW, KodamaT, Burns DPW, Ringler DJ, King NW, Daniel MD, Desrosiers RC. Nonhuman primate models for human letivirus infection and their use in vaccine research. Retroviruses of Human A.I.D.S. and Related Animal Disease. Girard M and Valette L (eds). 1989; 287-92.
  269. Wyand MS, Ringler DJ, Mattmuller M, Daniel MD, Desrosiers RC, King NW. Detection of simian immunodeficiency virus in macaque lymph nodes with a SIVmac envelope probe. J Med Primatol. 1989; 18(3-4):209-15.
    View in: PubMed
  270. Lee SI, Murthy SC, Trimble JJ, Desrosiers RC, Steitz JA. Four novel U RNAs are encoded by a herpesvirus. Cell. 1988 Aug 26; 54(5):599-607.
    View in: PubMed
  271. Fultz PN, Switzer WM, Schable CA, Desrosiers RC, Silva DP, McCormick JB. Seroprevalence of HIV-1 and HIV-2 in Guinea Bissau in 1980. AIDS. 1988 Apr; 2(2):129-32.
    View in: PubMed
  272. Trimble JJ, Murthy SC, Bakker A, Grassmann R, Desrosiers RC. A gene for dihydrofolate reductase in a herpesvirus. Science. 1988 Mar 4; 239(4844):1145-7.
    View in: PubMed
  273. Kestler HW, Li Y, Naidu YM, Butler CV, Ochs MF, Jaenel G, King NW, Daniel MD, Desrosiers RC. Comparison of simian immunodeficiency virus isolates. Nature. 1988 Feb 18; 331(6157):619-22.
    View in: PubMed
  274. Desrosiers RC. Simian immunodeficiency viruses. Annu Rev Microbiol. 1988; 42:607-25.
    View in: PubMed
  275. Daniel MD, Letvin NL, Sehgal PK, Schmidt DK, Silva DP, Solomon KR, Hodi FS, Ringler DJ, Hunt RD, King NW, Desrosiers RC. Prevalence of antibodies to 3 retroviruses in a captive colony of macaque monkeys. Int J Cancer. 1988; (239):1145-47.
  276. Desrosiers RC, Sehgal P, Letvin N, King N, Ringler D, Wyand M, Naidu Y, Kestler H, Gritz L, Mazzara G, McKenzie S, Panicali D, Daniel MD. SIV vaccine studies in rhesus monkeys. Retroviruses of Human A.I.D.S. and Related Animal Diseases. Girard M and Valette L (eds.). 1988; 258-261.
  277. Ringler DJ, Hunt RD, Desrosiers RC, Daniel MD, Chalifoux LV, King NW. Simian immunodeficiency virus-induced meningoencephalitis: natural history and retrospective study. Ann Neurol. 1988; 23 Suppl:S101-7.
    View in: PubMed
  278. Naidu YM, Kestler HW, Li Y, Butler CV, Silva DP, Schmidt KD, Troup CD, Sehgal PK, Sonigo P, Daniel MD Desrosiers RC. Characterization of infectious molecular clones of simian immunodeficiency virus (SIVmac) and human immunodeficiency virus type 2: persistent infection of rhesus monkeys with molecularly cloned SIVmac. J Virol. 1988; (62):4691-96.
  279. Daniel MD, Letvin NL, Sehgal PK, Hunsmann G, Schmidt DK, King NW, Desrosiers RC. Long-term persistent infection of macaque monkeys with the simian immunodeficiency virus. J Gen Virol. 1987 Dec; 68 ( Pt 12):3183-9.
    View in: PubMed
  280. Letvin NL, Daniel MD, Sehgal PK, Yetz JM, Solomon KR, Kannagi M, Schmidt DK, Silva DP, Montagnier L, Desrosiers RC. Infection of baboons with human immunodeficiency virus-2 (HIV-2) J Infect Dis. 1987 Aug; 156(2):406-7.
    View in: PubMed
  281. Chakrabarti L, Guyader M, Alizon M, Daniel MD, Desrosiers RC, Tiollais P, Sonigo P. Sequence of simian immunodeficiency virus from macaque and its relationship to other human and simian retroviruses. Nature. 1987 Aug 6-12; 328(6130):543-7.
    View in: PubMed
  282. Thielan BJ, Hunter E, Desrosiers RC, Ratner L. Trans-activation of long terminal repeat sequence-mediated gene expression is not a property of type D retrovirus replication. J Gen Virol. 1987 Aug; 68 ( Pt 8):2265-70.
    View in: PubMed
  283. Chalifoux LV, Ringler DJ, King NW, Sehgal PK, Desrosiers RC, Daniel MD, Letvin NL. Lymphadenopathy in macaques experimentally infected with the simian immunodeficiency virus (SIV). Am J Pathol. 1987 Jul; 128(1):104-10.
    View in: PubMed
  284. Desrosiers RC, Daniel MD, Letvin NL, King NW, Hunt RD. Origins of HTLV-4. Nature. 1987 May 14-20; 327(6118):107.
    View in: PubMed
  285. Desrosiers RC, Letvin NL. Animal models for acquired immunodeficiency syndrome. Rev Infect Dis. 1987 May-Jun; 9(3):438-46.
    View in: PubMed
  286. Ringler DJ, Hancock WW, King NW, Letvin NL, Daniel MD, Desrosiers RC, Murphy GF. Immunophenotypic characterization of the cutaneous exanthem of SIV-infected rhesus monkeys. Apposition of degenerative Langerhans cells and cytotoxic lymphocytes during the development of acquired immunodeficiency syndrome. Am J Pathol. 1987 Feb; 126(2):199-207.
    View in: PubMed
  287. Desrosiers RC, Letvin NL, King NW, Hunt RD, Blake BJ, Arthur LO, Daniel MD. Three retroviruses infecting macaques at the New England Regional Primate Research Center. New Series. Viruses and Human Cancer, UCLA Symposia on Molecular and Cellular Biology. 1987; 43:451-66.
  288. Letvin NL, Daniel MD, King NW, Kiyotak M, Kannagi M, Chalifoux LV, Sehgal PK, Arthur LO, Allison AC, Desrosiers RC. AIDS-like disease in macaque monkeys induced by simian immunodeficiency virus: a vaccine trial. Vaccines 87. 1987; 209-13.
  289. Letvin NL, Daniel MD, King NW, Arthur LO, Kiyotaki M and Desrosiers RC. . An HIV Related Virus from Macaques. Ann Inst Pasteur/Virol. 1987; (138):79-82.
  290. Uckert W, Wunderlich V, Fiebach H, Hertling I, Stein U, Kraft R, Desrosiers R. Biochemical and immunological characterization of structural proteins from retrovirus-D/New England and comparison to Mason-Pfizer monkey virus and permanent human fibroblast virus. Arch Virol. 1987; 94(3-4):267-82.
    View in: PubMed
  291. Schneider J, Jurkiewicz E, Wendler I, Jentsch KD, Bayer H, Desrosiers RC, Gelderblom H, and Hunsmann G. Structural, biochemical and serological comparison of LAV/HTLV-III and STLV-IIIMAC to primate lentiviruses. Viruses and Human Cancer, UCLA Symposia on Molecular and Cellular Biology, New Series. Gallo RG, Haseltine W, Klein G and zur Hausen H (eds). 1987; 43:319-32.
  292. Desrosiers RC, Murthy S and Trimble J. A region of the herpesvirus saimiri genome required for oncogenicity. Viruses and Human Cancer UCLA Symposia on Moleuclar and Cellular Biology. 1987; 43:309-317.
  293. Daniel MD, Desrosiers RC, Letvin NL, King NW, Schmidt DK, Sehgal P, Hunt RD. Simian models for AIDS. Cancer Detect Prev Suppl. 1987; 1:501-7.
    View in: PubMed
  294. Kannagi M, Kiyotaki M, Desrosiers RC, Reimann KA, King NW, Waldron LM, Letvin NL. Humoral immune responses to T cell tropic retrovirus simian T lymphotropic virus type III in monkeys with experimentally induced acquired immune deficiency-like syndrome. J Clin Invest. 1986 Nov; 78(5):1229-36.
    View in: PubMed
  295. Kiyotaki M, Desrosiers RC, Letvin NL. Herpesvirus saimiri strain 11 immortalizes a restricted marmoset T8 lymphocyte subpopulation in vitro. J Exp Med. 1986 Sep 1; 164(3):926-31.
    View in: PubMed
  296. Murthy S, Kamine J, Desrosiers RC. Viral-encoded small RNAs in herpes virus saimiri induced tumors. EMBO J. 1986 Jul; 5(7):1625-32.
    View in: PubMed
  297. Chalifoux LV, King NW, Daniel MD, Kannagi M, Desrosiers RC, Sehgal PK, Waldron LM, Hunt RD, Letvin NL. Lymphoproliferative syndrome in an immunodeficient rhesus monkey naturally infected with an HTLV-III-like virus (STLV-III). Lab Invest. 1986 Jul; 55(1):43-50.
    View in: PubMed
  298. Desrosiers RC. Origin of the human AIDS virus. Nature. 1986 Feb 27-Mar 5; 319(6056):728.
    View in: PubMed
  299. Desrosiers RC, Silva DP, Waldron LM, Letvin NL. Nononcogenic deletion mutants of herpesvirus saimiri are defective for in vitro immortalization. J Virol. 1986 Feb; 57(2):701-5.
    View in: PubMed
  300. Desrosiers RC. Simian Retrovirus. Animal Models of Retrovirus Infection and Their Relationship to AIDS, Salzman LA (ed). 1986; 145-53.
  301. Desrosiers R, Tanguay RM. The modifications in the methylation patterns of H2B and H3 after heat shock can be correlated with the inactivation of normal gene expression. Biochem Biophys Res Commun. 1985 Dec 17; 133(2):823-9.
    View in: PubMed
  302. Letvin NL, Daniel MD, Sehgal PK, Desrosiers RC, Hunt RD, Waldron LM, MacKey JJ, Schmidt DK, Chalifoux LV, King NW. Induction of AIDS-like disease in macaque monkeys with T-cell tropic retrovirus STLV-III. Science. 1985 Oct 4; 230(4721):71-3.
    View in: PubMed
  303. Desrosiers RC, Kamine J, Bakker A, Silva D, Woychik RP, Sakai DD, Rottman FM. Synthesis of bovine growth hormone in primates by using a herpesvirus vector. Mol Cell Biol. 1985 Oct; 5(10):2796-803.
    View in: PubMed
  304. Daniel MD, Letvin NL, King NW, Kannagi M, Sehgal PK, Hunt RD, Kanki PJ, Essex M, Desrosiers RC. Isolation of T-cell tropic HTLV-III-like retrovirus from macaques. Science. 1985 Jun 7; 228(4704):1201-4.
    View in: PubMed
  305. Kanki PJ, McLane MF, King NW, Letvin NL, Hunt RD, Sehgal P, Daniel MD, Desrosiers RC, Essex M. Serologic identification and characterization of a macaque T-lymphotropic retrovirus closely related to HTLV-III. Science. 1985 Jun 7; 228(4704):1199-201.
    View in: PubMed
  306. Desrosiers RC, Daniel MD, Butler CV, Schmidt DK, Letvin NL, Hunt RD, King NW, Barker CS, Hunter E. Retrovirus D/New England and its relation to Mason-Pfizer monkey virus. J Virol. 1985 May; 54(2):552-60.
    View in: PubMed
  307. Desrosiers RC, Bakker A, Kamine J, Falk LA, Hunt RD, King NW. A region of the Herpesvirus saimiri genome required for oncogenicity. Science. 1985 Apr 12; 228(4696):184-7.
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  308. Hunter E, Barker CS, Bradac J, Chatterjee S, Desrosiers R and Wills JW. Molecular Comparisons of the D-Type Retrovirus. Chapter 27. RNA Tumor Viruses, Oncogenes Human Cancer and AIDS: On the Frontiers of Understanding. Furmanski, P (ed). 1985; 338-53.
  309. Medveczky P, Szomolanyi E, Desrosiers RC, Mulder C. Classification of herpesvirus saimiri into three groups based on extreme variation in a DNA region required for oncogenicity. J Virol. 1984 Dec; 52(3):938-44.
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  310. Kamine J, Bakker A, Desrosiers RC. Mapping of RNA transcribed from a region of the Herpesvirus saimiri genome required for oncogenicity. J Virol. 1984 Nov; 52(2):532-40.
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  311. Letvin NL, Daniel MD, Sehgal PK, Chalifoux LV, King NW, Hunt RD, Aldrich WR, Holley K, Schmidt DK, Desrosiers RC. Experimental infection of rhesus monkeys with type D retrovirus. J Virol. 1984 Nov; 52(2):683-6.
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  312. Homma T, Kanki PJ, King NW, Hunt RD, O'Connell MJ, Letvin NL, Daniel MD, Desrosiers RC, Yang CS, Essex M. Lymphoma in macaques: association with virus of human T lymphotrophic family. Science. 1984 Aug 17; 225(4663):716-8.
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  313. Rabin H, Hopkins RF, Desrosiers RC, Ortaldo JR, Djeu JY, Neubauer RH. Transformation of owl monkey T cells in vitro with Herpesvirus saimiri. Proc Natl Acad Sci U S A. 1984 Jul; 81(14):4563-7.
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  314. Koomey JM, Mulder C, Burghoff RL, Fleckenstein B, Desrosiers RC. Deletion of DNA sequence in a nononcogenic variant of Herpesvirus saimiri. J Virol. 1984 May; 50(2):662-5.
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  315. Schirm S, Müller I, Desrosiers RC, Fleckenstein B. Herpesvirus saimiri DNA in a lymphoid cell line established by in vitro transformation. J Virol. 1984 Mar; 49(3):938-46.
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  316. Daniel MD, King NW, Letvin NL, Hunt RD, Sehgal PK, Desrosiers RC. A new type D retrovirus isolated from macaques with an immunodeficiency syndrome. Science. 1984 Feb 10; 223(4636):602-5.
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  317. Desrosiers RC, Burghoff RL, Bakker A, Kamine J. Construction of replication-competent Herpesvirus saimiri deletion mutants. J Virol. 1984 Feb; 49(2):343-8.
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  318. Letvin NL, Daniel MD, Hunt RD, King NW, Desrosiers RC. An Immunodeficiency Syndrome in Macaque Monkeys. Laboratory Primate Newsletter. 1984; (23:2):1-2.
  319. Desrosiers RC, Fleckenstein B. Oncogenic Transformation by Herpesvirus saimiri. Advances in Viral Oncology. Klein G (ed). 1983; 3(3):307-324.
  320. Desrosiers RC. Specifically unmethylated cytidylic-guanylate sites in Herpesvirus saimiri DNA in tumor cells. J Virol. 1982 Aug; 43(2):427-35.
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  321. Desrosiers RC, Falk LA. Herpesvirus saimiri strain variability. J Virol. 1982 Jul; 43(1):352-6.
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  322. Fleckenstein B and Desroseirs RC. Herpesvirus saimiri and Herpesvirus ateles. Chapter 6. The Herpesviruses. 1982; 1:253-332.
  323. Desrosiers RC, Hunt RD. Malignant Lymphoma, Model No. 60. In Handbook: Animal Models of Human Disease. Fasc. 11 CC apen, DB Hackel, TC Jones, G Migaki. 1982.
  324. Desrosiers RC, Falk LA. Herpesvirus tamarinus and its relation to herpes simplex virus. J Gen Virol. 1981 Sep; 56(Pt 1):119-30.
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  325. Desrosiers RC. Herpesvirus saimiri DNA in tumor cells--deleted sequences and sequence rearrangements. J Virol. 1981 Aug; 39(2):497-509.
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  326. Kaschka-Dierich C, Bauer I, Fleckenstein B, Desrosiers RC. Episomal and nonepisomal herpesvirus DNA in lymphoid tumor cell lines. Haematol Blood Transfus. 1981; 26:197-203.
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  327. Tracy S, Desrosiers RC. RNA from unique and repetitive DNA sequences of Herpesvirus saimiri. Virology. 1980 Jan 15; 100(1):204-7.
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  328. Falk L, Desrosiers RC, Hunt RD. Herpesvirus saimiri infection in squirrel and marmoset monkeys. Viruses in Naturally Occurring Cancers. Essex M, zur Hausen H, Todaro G, eds. 1980; (7):137-143.
  329. Lengyel P, Desrosiers RC, Broeze R, Slattery E, Taira H, Dougherty J, Samanta H, Pichon J, Farrell P, Ratner L, Sen G. Biochemistry of the Interferon System. Microbiology. David Schlessinger. 1980; (49):219-226.
  330. Desrosiers RC, Mulder C, Fleckenstein B. Methylation of Herpesvirus saimiri DNA in lymphoid tumor cell lines. Proc Natl Acad Sci U S A. 1979 Aug; 76(8):3839-43.
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  331. Desrosiers RC, Lengyel P. Impairment of reovirus mRNA 'cap' methylation in interferon-treated mouse L929 cells. Biochim Biophys Acta. 1979 May 24; 562(3):471-80.
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  332. Werner FJ, Desrosiers RC, Mulder C, Bornkamm GW, Fleckenstein B. Physical mapping of viral episomes in Herpesvirus saimiri transformed lymphoid cells. Persistent Viruses: ICN-UCLA Symposia in Molecular and Cellular Biology. Stevens JG, Todaro GJ, Fox CF (eds.). 1978; XI:189-200.
  333. Sen GC, Shaila S, Lebleu B, Brown GE, Desrosiers RC, Lengyel P. Impairment of reovirus mRNA methylation in extracts of interferon-treated Ehrilich ascites tumor cells: further characteristics of the phenomenon. J Virol. 1977 Jan; 21(1):69-83.
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  334. Sen GC, Desrosiers R, Ratner L, Shaila S, Brown GE, Lebleu B, Slattery E, Kawakita M, Cabrer B, Taira H, Lengyel P. Messenger RNA methylation, translation and degradation in extracts of interferon-treated cells. Tex Rep Biol Med. 1977; 35:221-9.
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  335. Desrosiers RC, Sen GC, Lengyel P. Difference in 5' terminal structure between the mRNA and the double-stranded virion RNA of reovirus. Biochem Biophys Res Commun. 1976 Nov 8; 73(1):32-9.
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  336. Desrosiers RC, Rottman FM, Boezi JA, Towle HC. The sensitivity of RNA polymerases I and II from Novikoff hepatoma (N1S1) cells to 3'-deoxyadenosine 5'-triphosphate. Nucleic Acids Res. 1976 Feb; 3(2):325-41.
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  337. Rottman FM, Desrosiers RC, Friderici K. Nucleotide methylation patterns in eukaryotic mRNA. Prog Nucleic Acid Res Mol Biol. 1976; 19:21-38.
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  338. Desrosiers RC, Friderici KH, Rottman FM. Characterization of Novikoff hepatoma mRNA methylation and heterogeneity in the methylated 5' terminus. Biochemistry. 1975 Oct 7; 14(20):4367-74.
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  339. Desrosiers R, Friderici K, Rottman F. Identification of methylated nucleosides in messenger RNA from Novikoff hepatoma cells. Proc Natl Acad Sci U S A. 1974 Oct; 71(10):3971-5.
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  340. Desrosiers RC, Friderici KH, Rottman FM. Identification methylated nucleosides in messenger RNA from Novikoff hepatoma cells. Proc Natl Acad Sci USA. 1974; (1971):3971-75.
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