 Griffin M Weber, M.D., Ph.D.
| Title | Chief Technology Officer |
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| Institution | Harvard Medical School |
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| Department | IT |
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| Address | Harvard Medical School
Information Technology
107 Avenue Louis Pasteur
Boston MA 02115
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| Phone | 617/998-6659 |
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| Fax | 617/432-1150 |
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| Title | Assistant Professor of Medicine |
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| Institution | Beth Israel Deaconess Medical Center |
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| Department | Medicine |
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| Division | Interdisciplinary Medicine and Biotechnology |
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 Biography | 2003 -
| Lee B. Lusted Student Prize | | 2007 -
| Massachusetts Medical Society Medical Technology Award | | 2010 -
| Distinguished Poster Award at AMIA 2010 Annual Symposium | | 2011 -
| Top Podium Presentation at AMIA 2011 Joint Summits on Translational Science |
Overview Dr. Griffin Weber is the Chief Technology Officer of Harvard Medical School (HMS); an Assistant Professor of Medicine at HMS in Division of Interdisciplinary Medicine and Biotechnology, Department of Medicine, Beth Israel Deaconess Medical Center (BIDMC); the Director of the Biomedical Research Informatics Core (BRIC) at BIDMC; and the Academic Analytics Advisor to the Office of the Provost at Harvard University.
Dr. Weber's research involves expertise mining and social network analysis. He invented the Harvard Catalyst Profiles website, which contains research profiles for 20,000 faculty that are linked together through both Passive Networks, which are automatically generated based on information known about investigators, and Active Networks, which users create themselves by indicating their relationships to other researchers. These networks have numerous applications, ranging from finding individual collaborators and mentors to understanding the dynamics of an entire research community. The open source software is used at dozens of institutions worldwide.
Dr. Weber is also an investigator on Informatics for Integrating Biology and the Bedside (i2b2), an NIH National Center for Biomedical Computing, for which he helped developed a web-based open source platform that enables a variety of functions including queries of large clinical repositories, visualization of temporal data, identification of random matched cohorts, and statistical comparison of groups of patients. He also created the Shared Health Research Information Network (SHRINE), which is a federated query tool that connects multiple i2b2 databases. The i2b2 software is currently used over 80 academic health centers.
Dr. Weber received his MD and PhD in computer science from Harvard University. In 1997, while still a student, he developed one of the first hospital-wide web-based electronic medical record systems. He also found time between thesis writing and clinical rotations to analyze DNA microarrays, model the growth of breast cancer tumors, create award-winning algorithms for predicting life expectancy, and build an educational web portal that provides interactive online content to over 500 courses at Harvard Medical School.
Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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McMurry AJ, Murphy SN, Macfadden D, Weber G, Simons WW, Orechia J, Bickel J, Wattanasin N, Gilbert C, Trevvett P, Churchill S, Kohane IS. SHRINE: Enabling Nationally Scalable Multi-Site Disease Studies. PLoS One. 2013; 8(3):e55811.
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Weber GM. Federated queries of clinical data repositories: the sum of the parts does not equal the whole. J Am Med Inform Assoc. 2013 Jan 24.
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Natter MD, Quan J, Ortiz DM, Bousvaros A, Ilowite NT, Inman CJ, Marsolo K, McMurry AJ, Sandborg CI, Schanberg LE, Wallace CA, Warren RW, Weber GM, Mandl KD. An i2b2-based, generalizable, open source, self-scaling chronic disease registry. J Am Med Inform Assoc. 2013 Jan 1; 20(1):172-9.
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Kohane IS, McMurry A, Weber G, MacFadden D, Rappaport L, Kunkel L, Bickel J, Wattanasin N, Spence S, Murphy S, Churchill S. The co-morbidity burden of children and young adults with autism spectrum disorders. PLoS One. 2012; 7(4):e33224.
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Murphy SN, Dubey A, Embi PJ, Harris PA, Richter BG, Turisco F, Weber GM, Tcheng JE, Keogh D. Current state of information technologies for the clinical research enterprise across academic medical centers. Clin Transl Sci. 2012 Jun; 5(3):281-4.
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Weber GM, Barnett W, Conlon M, Eichmann D, Kibbe W, Falk-Krzesinski H, Halaas M, Johnson L, Meeks E, Mitchell D, Schleyer T, Stallings S, Warden M, Kahlon M. Direct2Experts: a pilot national network to demonstrate interoperability among research-networking platforms. J Am Med Inform Assoc. 2011 Dec; 18 Suppl 1:i157-60.
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Wang KC, Jeanmenne A, Weber GM, Thawait SK, Thawait S, Carrino JA. An online evidence-based decision support system for distinguishing benign from malignant vertebral compression fractures by magnetic resonance imaging feature analysis. J Digit Imaging. 2011 Jun; 24(3):507-15.
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Murphy SN, Weber G, Mendis M, Gainer V, Chueh HC, Churchill S, Kohane I. Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2). J Am Med Inform Assoc. 2010 Mar-Apr; 17(2):124-30.
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Milo R, Jorgensen P, Moran U, Weber G, Springer M. BioNumbers--the database of key numbers in molecular and cell biology. Nucleic Acids Res. 2010 Jan; 38(Database issue):D750-3.
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Weber GM, Murphy SN, McMurry AJ, Macfadden D, Nigrin DJ, Churchill S, Kohane IS. The Shared Health Research Information Network (SHRINE): a prototype federated query tool for clinical data repositories. J Am Med Inform Assoc. 2009 Sep-Oct; 16(5):624-30.
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Shen LQ, Child A, Weber GM, Folkman J, Aiello LP. Rosiglitazone and delayed onset of proliferative diabetic retinopathy. Arch Ophthalmol. 2008 Jun; 126(6):793-9.
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Weber G, Weber G. Pizza Combinatorics Revisited. The College Mathematics Journal. 2006; 37(1):43-4.
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Weber G, Ohno-Machado L, Shieber S. Representation in stochastic search for phylogenetic tree reconstruction. J Biomed Inform. 2006 Feb; 39(1):43-50.
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Col NF, Weber G, Stiggelbout A, Chuo J, D'Agostino R, Corso P. Short-term menopausal hormone therapy for symptom relief: an updated decision model. Arch Intern Med. 2004 Aug 9-23; 164(15):1634-40.
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Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL. Genomic analysis of mouse retinal development. PLoS Biol. 2004 Sep; 2(9):E247.
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Weber G, Vinterbo S, Ohno-Machado L. Multivariate selection of genetic markers in diagnostic classification. Artif Intell Med. 2004 Jun; 31(2):155-67.
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Xu Y, Stange-Thomann N, Weber G, Bo R, Dodge S, David RG, Foley K, Beheshti J, Harris NL, Birren B, Lander ES, Meyerson M. Pathogen discovery from human tissue by sequence-based computational subtraction. Genomics. 2003 Mar; 81(3):329-35.
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Michaelson JS, Satija S, Moore R, Weber G, Halpern E, Garland A, Kopans DB. Journal of Women's Imaging. Estimates of Breast Cancer Growth Rate and Sojourn Time from Screening Database Information. 2003; (1):11-19.
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Michaelson JS, Satija S, Moore R, Weber G, Halpern E, Garland A, Kopans DB. Journal of Women's Imaging. Estimates of the Sizes at Which Breast Cancers Become Detectable on Mammographic and Clinical Grounds. 2003; (1):3-10.
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Michaelson JS, Silverstein M, Wyatt J, Weber G, Moore R, Halpern E, Kopans DB, Hughes K. Predicting the survival of patients with breast carcinoma using tumor size. Cancer. 2002 Aug 15; 95(4):713-23.
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Weber G, Shendure J, Tanenbaum DM, Church GM, Meyerson M. Identification of foreign gene sequences by transcript filtering against the human genome. Nat Genet. 2002 Feb; 30(2):141-2.
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Col NF, Fortin JM, Weber G. Clearinghouse Number JC020766. Using the Web to Promote Smoking Cessation and Health for College-Aged Women. Educational Resources Information Center. 2002.
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Weber G, Vinterbo S, Ohno-Machado L. Building an asynchronous web-based tool for machine learning classification. Proc AMIA Symp. 2002; 869-73.
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Ohno-Machado L, Vinterbo S, Weber G. Journal of Intelligent and Fuzzy Systems. Classification of Gene Expression Data Using Fuzzy Logic. 2002; 12(1):19-24.
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Michaelson J, Satija S, Moore R, Weber G, Halpern E, Garland A, Puri D, Kopans DB. The pattern of breast cancer screening utilization and its consequences. Cancer. 2002 Jan 1; 94(1):37-43.
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Bhattacharjee A, Richards WG, Staunton J, Li C, Monti S, Vasa P, Ladd C, Beheshti J, Bueno R, Gillette M, Loda M, Weber G, Mark EJ, Lander ES, Wong W, Johnson BE, Golub TR, Sugarbaker DJ, Meyerson M. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc Natl Acad Sci U S A. 2001 Nov 20; 98(24):13790-5.
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Comander J, Weber GM, Gimbrone MA, García-Cardeña G. Argus--a new database system for Web-based analysis of multiple microarray data sets. Genome Res. 2001 Sep; 11(9):1603-10.
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Michaelson JS, Satija S, Moore R, Weber G, Halpern E, Garland A, Kopans DB. Journal of Women's Imaging. Observations on Invasive Breast Cancer Diagnosed in a Service Screening and Diagnostic Breast Imaging Program. 2001; 3:99-104.
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Weber G, Weber G. Pizza Combinatorics. The College Mathematics Journal. 1995; 26(2):141-3.
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