Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Last Name

Griffin M Weber, M.D., Ph.D.

TitleHead of the Knowledge Discovery & Management Group
InstitutionHarvard Medical School
DepartmentCenter for Biomedical Informatics at Countway
AddressHarvard Medical School
Information Technology
107 Avenue Louis Pasteur
Boston MA 02115
Other Positions
TitleAssistant Professor of Medicine
InstitutionBeth Israel Deaconess Medical Center
DivisionInterdisciplinary Medicine and Biotechnology

 awards and honors
2003 - Lee B. Lusted Student Prize
2007 - Massachusetts Medical Society Medical Technology Award
2010 - Distinguished Poster Award at AMIA 2010 Annual Symposium
2011 - Top Podium Presentation at AMIA 2011 Joint Summits on Translational Science

Dr. Griffin Weber is the Chief Technology Officer of Harvard Medical School (HMS); an Assistant Professor of Medicine at HMS in Division of Interdisciplinary Medicine and Biotechnology, Department of Medicine, Beth Israel Deaconess Medical Center (BIDMC); the Director of the Biomedical Research Informatics Core (BRIC) at BIDMC; and the Academic Analytics Advisor to the Office of the Provost at Harvard University.

Dr. Weber's research involves expertise mining and social network analysis. He invented the Harvard Catalyst Profiles website, which contains research profiles for 20,000 faculty that are linked together through both Passive Networks, which are automatically generated based on information known about investigators, and Active Networks, which users create themselves by indicating their relationships to other researchers. These networks have numerous applications, ranging from finding individual collaborators and mentors to understanding the dynamics of an entire research community. The open source software is used at dozens of institutions worldwide.

Dr. Weber is also an investigator on Informatics for Integrating Biology and the Bedside (i2b2), an NIH National Center for Biomedical Computing, for which he helped developed a web-based open source platform that enables a variety of functions including queries of large clinical repositories, visualization of temporal data, identification of random matched cohorts, and statistical comparison of groups of patients. He also created the Shared Health Research Information Network (SHRINE), which is a federated query tool that connects multiple i2b2 databases. The i2b2 software is currently used over 80 academic health centers.

Dr. Weber received his MD and PhD in computer science from Harvard University. In 1997, while still a student, he developed one of the first hospital-wide web-based electronic medical record systems. He also found time between thesis writing and clinical rotations to analyze DNA microarrays, model the growth of breast cancer tumors, create award-winning algorithms for predicting life expectancy, and build an educational web portal that provides interactive online content to over 500 courses at Harvard Medical School.

 research resources
This researcher has shared information about their research resources
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Biomedical Research Informatics Core Laboratory (BIDMC) - Core services (1) and Software (1)

 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Kahlon M, Yuan L, Daigre J, Meeks E, Nelson K, Piontkowski C, Reuter K, Sak R, Turner B, Weber GM, Chatterjee A. The use and significance of a research networking system. J Med Internet Res. 2014; 16(2):e46.
    View in: PubMed
  2. Weber GM, Kohane IS. Extracting physician group intelligence from electronic health records to support evidence based medicine. PLoS One. 2013; 8(5):e64933.
    View in: PubMed
  3. Weber GM. Identifying translational science within the triangle of biomedicine. J Transl Med. 2013; 11:126.
    View in: PubMed
  4. Weber GM. How many patients are "normal"? Only 1.55%. AMIA Summits Transl Sci Proc. 2013; 2013:79.
    View in: PubMed
  5. McMurry AJ, Murphy SN, Macfadden D, Weber G, Simons WW, Orechia J, Bickel J, Wattanasin N, Gilbert C, Trevvett P, Churchill S, Kohane IS. SHRINE: Enabling Nationally Scalable Multi-Site Disease Studies. PLoS One. 2013; 8(3):e55811.
    View in: PubMed
  6. Weber GM. Federated queries of clinical data repositories: the sum of the parts does not equal the whole. J Am Med Inform Assoc. 2013 Jun; 20(e1):e155-61.
    View in: PubMed
  7. Natter MD, Quan J, Ortiz DM, Bousvaros A, Ilowite NT, Inman CJ, Marsolo K, McMurry AJ, Sandborg CI, Schanberg LE, Wallace CA, Warren RW, Weber GM, Mandl KD. An i2b2-based, generalizable, open source, self-scaling chronic disease registry. J Am Med Inform Assoc. 2013 Jan 1; 20(1):172-9.
    View in: PubMed
  8. Kohane IS, McMurry A, Weber G, MacFadden D, Rappaport L, Kunkel L, Bickel J, Wattanasin N, Spence S, Murphy S, Churchill S. The co-morbidity burden of children and young adults with autism spectrum disorders. PLoS One. 2012; 7(4):e33224.
    View in: PubMed
  9. Murphy SN, Dubey A, Embi PJ, Harris PA, Richter BG, Turisco F, Weber GM, Tcheng JE, Keogh D. Current state of information technologies for the clinical research enterprise across academic medical centers. Clin Transl Sci. 2012 Jun; 5(3):281-4.
    View in: PubMed
  10. Weber GM, Barnett W, Conlon M, Eichmann D, Kibbe W, Falk-Krzesinski H, Halaas M, Johnson L, Meeks E, Mitchell D, Schleyer T, Stallings S, Warden M, Kahlon M. Direct2Experts: a pilot national network to demonstrate interoperability among research-networking platforms. J Am Med Inform Assoc. 2011 Dec; 18 Suppl 1:i157-60.
    View in: PubMed
  11. Wang KC, Jeanmenne A, Weber GM, Thawait SK, Thawait S, Carrino JA. An online evidence-based decision support system for distinguishing benign from malignant vertebral compression fractures by magnetic resonance imaging feature analysis. J Digit Imaging. 2011 Jun; 24(3):507-15.
    View in: PubMed
  12. Murphy SN, Weber G, Mendis M, Gainer V, Chueh HC, Churchill S, Kohane I. Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2). J Am Med Inform Assoc. 2010 Mar-Apr; 17(2):124-30.
    View in: PubMed
  13. Milo R, Jorgensen P, Moran U, Weber G, Springer M. BioNumbers--the database of key numbers in molecular and cell biology. Nucleic Acids Res. 2010 Jan; 38(Database issue):D750-3.
    View in: PubMed
  14. Weber GM, Murphy SN, McMurry AJ, Macfadden D, Nigrin DJ, Churchill S, Kohane IS. The Shared Health Research Information Network (SHRINE): a prototype federated query tool for clinical data repositories. J Am Med Inform Assoc. 2009 Sep-Oct; 16(5):624-30.
    View in: PubMed
  15. Shen LQ, Child A, Weber GM, Folkman J, Aiello LP. Rosiglitazone and delayed onset of proliferative diabetic retinopathy. Arch Ophthalmol. 2008 Jun; 126(6):793-9.
    View in: PubMed
  16. Weber G, Weber G. Pizza Combinatorics Revisited. The College Mathematics Journal. 2006; 37(1):43-4.
  17. Weber G, Ohno-Machado L, Shieber S. Representation in stochastic search for phylogenetic tree reconstruction. J Biomed Inform. 2006 Feb; 39(1):43-50.
    View in: PubMed
  18. Col NF, Weber G, Stiggelbout A, Chuo J, D'Agostino R, Corso P. Short-term menopausal hormone therapy for symptom relief: an updated decision model. Arch Intern Med. 2004 Aug 9-23; 164(15):1634-40.
    View in: PubMed
  19. Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL. Genomic analysis of mouse retinal development. PLoS Biol. 2004 Sep; 2(9):E247.
    View in: PubMed
  20. Weber G, Vinterbo S, Ohno-Machado L. Multivariate selection of genetic markers in diagnostic classification. Artif Intell Med. 2004 Jun; 31(2):155-67.
    View in: PubMed
  21. Xu Y, Stange-Thomann N, Weber G, Bo R, Dodge S, David RG, Foley K, Beheshti J, Harris NL, Birren B, Lander ES, Meyerson M. Pathogen discovery from human tissue by sequence-based computational subtraction. Genomics. 2003 Mar; 81(3):329-35.
    View in: PubMed
  22. Michaelson JS, Satija S, Moore R, Weber G, Halpern E, Garland A, Kopans DB. Journal of Women's Imaging. Estimates of Breast Cancer Growth Rate and Sojourn Time from Screening Database Information. 2003; (1):11-19.
  23. Michaelson JS, Satija S, Moore R, Weber G, Halpern E, Garland A, Kopans DB. Journal of Women's Imaging. Estimates of the Sizes at Which Breast Cancers Become Detectable on Mammographic and Clinical Grounds. 2003; (1):3-10.
  24. Michaelson JS, Silverstein M, Wyatt J, Weber G, Moore R, Halpern E, Kopans DB, Hughes K. Predicting the survival of patients with breast carcinoma using tumor size. Cancer. 2002 Aug 15; 95(4):713-23.
    View in: PubMed
  25. Weber G, Shendure J, Tanenbaum DM, Church GM, Meyerson M. Identification of foreign gene sequences by transcript filtering against the human genome. Nat Genet. 2002 Feb; 30(2):141-2.
    View in: PubMed
  26. Col NF, Fortin JM, Weber G. Clearinghouse Number JC020766. Using the Web to Promote Smoking Cessation and Health for College-Aged Women. Educational Resources Information Center. 2002.
  27. Weber G, Vinterbo S, Ohno-Machado L. Building an asynchronous web-based tool for machine learning classification. Proc AMIA Symp. 2002; 869-73.
    View in: PubMed
  28. Ohno-Machado L, Vinterbo S, Weber G. Journal of Intelligent and Fuzzy Systems. Classification of Gene Expression Data Using Fuzzy Logic. 2002; 12(1):19-24.
  29. Michaelson J, Satija S, Moore R, Weber G, Halpern E, Garland A, Puri D, Kopans DB. The pattern of breast cancer screening utilization and its consequences. Cancer. 2002 Jan 1; 94(1):37-43.
    View in: PubMed
  30. Bhattacharjee A, Richards WG, Staunton J, Li C, Monti S, Vasa P, Ladd C, Beheshti J, Bueno R, Gillette M, Loda M, Weber G, Mark EJ, Lander ES, Wong W, Johnson BE, Golub TR, Sugarbaker DJ, Meyerson M. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc Natl Acad Sci U S A. 2001 Nov 20; 98(24):13790-5.
    View in: PubMed
  31. Comander J, Weber GM, Gimbrone MA, García-Cardeña G. Argus--a new database system for Web-based analysis of multiple microarray data sets. Genome Res. 2001 Sep; 11(9):1603-10.
    View in: PubMed
  32. Michaelson JS, Satija S, Moore R, Weber G, Halpern E, Garland A, Kopans DB. Journal of Women's Imaging. Observations on Invasive Breast Cancer Diagnosed in a Service Screening and Diagnostic Breast Imaging Program. 2001; 3:99-104.
  33. Weber G, Weber G. Pizza Combinatorics. The College Mathematics Journal. 1995; 26(2):141-3.
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