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Institution

Herbert Ben Hechtman, M.D.

TitleProfessor of Surgery
InstitutionBrigham and Women's Hospital
DepartmentSurgery
AddressBrigham and Women's Hospital
Surgery - Carrie Hall Bldg.
75 Francis St
Boston MA 02115
Phone617/732-6098
Fax617/739-3927

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Hechtman HB. Clinical activity and mode of action of poly-N-acetyl glucosamine fiber materials: hemostasis and wound healing. Foreword. J Trauma. 2011 Aug; 71(2 Suppl 1):S161.
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  2. Scherer SS, Pietramaggiori G, Matthews J, Perry S, Assmann A, Carothers A, Demcheva M, Muise-Helmericks RC, Seth A, Vournakis JN, Valeri RC, Fischer TH, Hechtman HB, Orgill DP. Poly-N-acetyl glucosamine nanofibers: a new bioactive material to enhance diabetic wound healing by cell migration and angiogenesis. Ann Surg. 2009 Aug; 250(2):322-30.
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  3. Pietramaggiori G, Yang HJ, Scherer SS, Kaipainen A, Chan RK, Alperovich M, Newalder J, Demcheva M, Vournakis JN, Valeri CR, Hechtman HB, Orgill DP. Effects of poly-N-acetyl glucosamine (pGlcNAc) patch on wound healing in db/db mouse. J Trauma. 2008 Mar; 64(3):803-8.
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  4. Chan RK, Liu PH, Pietramaggiori G, Ibrahim SI, Hechtman HB, Orgill DP. Effect of recombinant platelet-derived growth factor (Regranex) on wound closure in genetically diabetic mice. J Burn Care Res. 2006 Mar-Apr; 27(2):202-5.
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  5. Chan RK, Liu P, Lew DH, Ibrahim SI, Srey R, Valeri CR, Hechtman HB, Orgill DP. Expired liquid preserved platelet releasates retain proliferative activity. J Surg Res. 2005 Jun 1; 126(1):55-8.
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  6. Chan RK, Ding G, Verna N, Ibrahim S, Oakes S, Austen WG, Hechtman HB, Moore FD. IgM binding to injured tissue precedes complement activation during skeletal muscle ischemia-reperfusion. J Surg Res. 2004 Nov; 122(1):29-35.
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  7. Chan RK, Austen WG, Ibrahim S, Ding GY, Verna N, Hechtman HB, Moore FD. Reperfusion injury to skeletal muscle affects primarily type II muscle fibers. J Surg Res. 2004 Nov; 122(1):54-60.
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  8. Austen WG, Zhang M, Chan R, Friend D, Hechtman HB, Carroll MC, Moore FD. Murine hindlimb reperfusion injury can be initiated by a self-reactive monoclonal IgM. Surgery. 2004 Aug; 136(2):401-6.
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  9. Favuzza J, Hechtman HB. Hemostasis in the absence of clotting factors. J Trauma. 2004 Jul; 57(1 Suppl):S42-4.
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  10. Zhang M, Austen WG, Chiu I, Alicot EM, Hung R, Ma M, Verna N, Xu M, Hechtman HB, Moore FD, Carroll MC. Identification of a specific self-reactive IgM antibody that initiates intestinal ischemia/reperfusion injury. Proc Natl Acad Sci U S A. 2004 Mar 16; 101(11):3886-91.
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  11. Chan RK, Ibrahim SI, Verna N, Carroll M, Moore FD, Hechtman HB. Ischaemia-reperfusion is an event triggered by immune complexes and complement. Br J Surg. 2003 Dec; 90(12):1470-8.
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  12. Austen WG, Kobzik L, Carroll MC, Hechtman HB, Moore FD. The role of complement and natural antibody in intestinal ischemia-reperfusion injury. Int J Immunopathol Pharmacol. 2003 Jan-Apr; 16(1):1-8.
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  13. Reid RR, Woodcock S, Shimabukuro-Vornhagen A, Austen WG, Kobzik L, Zhang M, Hechtman HB, Moore FD, Carroll MC. Functional activity of natural antibody is altered in Cr2-deficient mice. J Immunol. 2002 Nov 15; 169(10):5433-40.
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  14. Lieberthal W, Fuhro R, Alam H, Rhee P, Szebeni J, Hechtman HB, Favuzza J, Veech RL, Valeri CR. Comparison of the effects of a 50% exchange-transfusion with albumin, hetastarch, and modified hemoglobin solutions. Shock. 2002 Jan; 17(1):61-9.
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  15. Kyriakides C, Wang Y, Austen WG, Favuzza J, Kobzik L, Moore FD, Hechtman HB. Sialyl Lewis(x) hybridized complement receptor type 1 moderates acid aspiration injury. Am J Physiol Lung Cell Mol Physiol. 2001 Dec; 281(6):L1494-9.
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  16. Valeri CR, Dennis RC, Ragno G, Pivacek LE, Hechtman HB, Khuri SF. Survival, function, and hemolysis of shed red blood cells processed as nonwashed blood and washed red blood cells. Ann Thorac Surg. 2001 Nov; 72(5):1598-602.
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  17. Valeri CR, Ragno G, Pivacek LE, Dennis RC, Hechtman HB, Khuri SF. Survival and function of baboon RBCs released from clotted blood and washed before autologous transfusion. Transfusion. 2001 Nov; 41(11):1384-9.
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  18. Lim MJ, Chiang ET, Hechtman HB, Shepro D. Inflammation-induced subcellular redistribution of VE-cadherin, actin, and gamma-catenin in cultured human lung microvessel endothelial cells. Microvasc Res. 2001 Nov; 62(3):366-82.
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  19. Mukundan C, Gurish MF, Austen KF, Hechtman HB, Friend DS. Mast cell mediation of muscle and pulmonary injury following hindlimb ischemia-reperfusion. J Histochem Cytochem. 2001 Aug; 49(8):1055-6.
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  20. Kyriakides C, Austen WG, Wang Y, Favuzza J, Kobzik L, Moore FD, Hechtman HB. Mast cells mediate complement activation after acid aspiration. Shock. 2001 Jul; 16(1):21-4.
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  21. Kyriakides C, Wang Y, Austen WG, Favuzza J, Kobzik L, Moore FD, Hechtman HB. Moderation of skeletal muscle reperfusion injury by a sLe(x)-glycosylated complement inhibitory protein. Am J Physiol Cell Physiol. 2001 Jul; 281(1):C224-30.
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  22. Mukundan C, Gurish MF, Austen KF, Hechtman HB, Friend DS. The presence of v-abl-transformed V3 mast cells in the lungs augments pulmonary vascular permeability to acid aspiration. J Histochem Cytochem. 2001 Jun; 49(6):793-4.
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  23. Kyriakides C, Favuzza J, Wang Y, Austen WG, Moore FD, Hechtman HB. Recombinant soluble P-selectin glycoprotein ligand 1 moderates local and remote injuries following experimental lower-torso ischaemia. Br J Surg. 2001 Jun; 88(6):825-30.
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  24. Kyriakides C, Jasleen J, Wang Y, Moore FD, Ashley SW, Hechtman HB. Neutrophils, not complement, mediate the mortality of experimental hemorrhagic pancreatitis. Pancreas. 2001 Jan; 22(1):40-6.
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  25. Woodcock SA, Kyriakides C, Wang Y, Austen WG, Moore FD, Valeri R, Hartwell D, Hechtman HB. Soluble P-selectin moderates complement dependent injury. Shock. 2000 Dec; 14(6):610-5.
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  26. Kyriakides C, Austen W, Wang Y, Favuzza J, Moore FD, Hechtman HB. Endothelial selectin blockade attenuates lung permeability of experimental acid aspiration. Surgery. 2000 Aug; 128(2):327-31.
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  27. Kyriakides C, Woodcock SA, Wang Y, Favuzza J, Austen WG, Kobzik L, Moore FD, Valeri RC, Shepro D, Hechtman HB. Soluble P-selectin moderates complement-dependent reperfusion injury of ischemic skeletal muscle. Am J Physiol Cell Physiol. 2000 Aug; 279(2):C520-8.
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  28. Kyriakides C, Austen WG, Wang Y, Favuzza J, Moore FD, Hechtman HB. Neutrophil mediated remote organ injury after lower torso ischemia and reperfusion is selectin and complement dependent. J Trauma. 2000 Jan; 48(1):32-8.
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  29. Reid RR, Woodcock S, Prodeus AP, Austen J, Kobzik L, Hechtman H, Moore FD, Carroll MC. The role of complement receptors CD21/CD35 in positive selection of B-1 cells. Curr Top Microbiol Immunol. 2000; 252:57-65.
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  30. Kyriakides C, Austen W, Wang Y, Favuzza J, Kobzik L, Moore FD, Hechtman HB. Skeletal muscle reperfusion injury is mediated by neutrophils and the complement membrane attack complex. Am J Physiol. 1999 Dec; 277(6 Pt 1):C1263-8.
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  31. Kyriakides C, Austen W, Wang Y, Favuzza J, Kobzik L, Moore FD, Hechtman HB. Membrane attack complex of complement and neutrophils mediate the injury of acid aspiration. J Appl Physiol. 1999 Dec; 87(6):2357-61.
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  32. Shojaee N, Patton WF, Hechtman HB, Shepro D. Myosin translocation in retinal pericytes during free-radical induced apoptosis. J Cell Biochem. 1999 Oct 1; 75(1):118-29.
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  33. Austen WG, Kyriakides C, Favuzza J, Wang Y, Kobzik L, Moore FD, Hechtman HB. Intestinal ischemia-reperfusion injury is mediated by the membrane attack complex. Surgery. 1999 Aug; 126(2):343-8.
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  34. Barnard MR, MacGregor H, Mercier R, Ragno G, Pivacek LE, Hechtman HB, Michelson AD, Valeri CR. Platelet surface p-selectin, platelet-granulocyte heterotypic aggregates, and plasma-soluble p-selectin during plateletpheresis. Transfusion. 1999 Jul; 39(7):735-41.
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  35. Williams JP, Pechet TT, Weiser MR, Reid R, Kobzik L, Moore FD, Carroll MC, Hechtman HB. Intestinal reperfusion injury is mediated by IgM and complement. J Appl Physiol. 1999 Mar; 86(3):938-42.
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  36. Peyton BD, Rohrer MJ, Furman MI, Barnard MR, Rodino LJ, Benoit SE, Hechtman HB, Valeri CR, Michelson AD. Patients with venous stasis ulceration have increased monocyte-platelet aggregation. J Vasc Surg. 1998 Jun; 27(6):1109-15; discussion 1115-6.
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  37. Hastie LE, Patton WF, Hechtman HB, Shepro D. Metabolites of the phospholipase D pathway regulate H2O2-induced filamin redistribution in endothelial cells. J Cell Biochem. 1998 Mar 15; 68(4):511-24.
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  38. Shojaee N, Patton WF, Chung-Welch N, Su Q, Hechtman HB, Shepro D. Expression and subcellular distribution of filamin isotypes in endothelial cells and pericytes. Electrophoresis. 1998 Feb; 19(2):323-32.
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  39. Furman MI, Benoit SE, Barnard MR, Valeri CR, Borbone ML, Becker RC, Hechtman HB, Michelson AD. Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease. J Am Coll Cardiol. 1998 Feb; 31(2):352-8.
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  40. Wang Q, Patton WF, Hechtman HB, Shepro D. Activation of endothelial cell kinin receptors leads to intracellular calcium increases and filamin translocation: regulation by protein kinase C. Cell Signal. 1997 Dec; 9(8):595-602.
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  41. Williams JP, Weiser MR, Pechet TT, Kobzik L, Moore FD, Hechtman HB. alpha 1-Acid glycoprotein reduces local and remote injuries after intestinal ischemia in the rat. Am J Physiol. 1997 Nov; 273(5 Pt 1):G1031-5.
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  42. Weiser MR, Pechet TT, Williams JP, Ma M, Frenette PS, Moore FD, Kobzik L, Hines RO, Wagner DD, Carroll MC, Hechtman HB. Experimental murine acid aspiration injury is mediated by neutrophils and the alternative complement pathway. J Appl Physiol. 1997 Oct; 83(4):1090-5.
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  43. Hastie LE, Patton WF, Hechtman HB, Shepro D. H2O2-induced filamin redistribution in endothelial cells is modulated by the cyclic AMP-dependent protein kinase pathway. J Cell Physiol. 1997 Sep; 172(3):373-81.
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  44. Wang Q, Patton WF, Hechtman HB, Shepro D. A novel anti-inflammatory peptide inhibits endothelial cell cytoskeletal rearrangement, nitric oxide synthase translocation, and paracellular permeability increases. J Cell Physiol. 1997 Aug; 172(2):171-82.
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  45. Morel NM, Xu CB, Hechtman HB, Shepro D. Microvessel mural cell secretions modulate endothelial monolayer permeability. Microvasc Res. 1997 Mar; 53(2):197-200.
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  46. Hastie LE, Patton WF, Hechtman HB, Shepro D. Filamin redistribution in an endothelial cell reoxygenation injury model. Free Radic Biol Med. 1997; 22(6):955-66.
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  47. Michelson AD, Barnard MR, Hechtman HB, MacGregor H, Connolly RJ, Loscalzo J, Valeri CR. In vivo tracking of platelets: circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11877-82.
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  48. Wang Q, Patton WF, Chiang ET, Hechtman HB, Shepro D. Filamin translocation is an early endothelial cell inflammatory response to bradykinin: regulation by calcium, protein kinases, and protein phosphatases. J Cell Biochem. 1996 Sep 1; 62(3):383-96.
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  49. Hechtman HB, Barlow C. Moderation of anal sphincter tone with nitric oxide agonists and antagonists. Arch Surg. 1996 Jul; 131(7):775-84.
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  50. Gibbs SA, Weiser MR, Kobzik L, Valeri CR, Shepro D, Hechtman HB. P-selectin mediates intestinal ischemic injury by enhancing complement deposition. Surgery. 1996 Jun; 119(6):652-6.
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  51. Weiser MR, Gibbs SA, Valeri CR, Shepro D, Hechtman HB. Anti-selectin therapy modifies skeletal muscle ischemia and reperfusion injury. Shock. 1996 Jun; 5(6):402-7.
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  52. Weiser MR, Williams JP, Moore FD, Kobzik L, Ma M, Hechtman HB, Carroll MC. Reperfusion injury of ischemic skeletal muscle is mediated by natural antibody and complement. J Exp Med. 1996 May 1; 183(5):2343-8.
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  53. Weiser MR, Gibbs SA, Moore FD, Hechtman HB. Complement inhibition by soluble complement receptor type 1 fails to moderate cerulein-induced pancreatitis in the rat. Int J Pancreatol. 1996 Apr; 19(2):129-34.
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  54. Goldman G, Welbourn R, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Neutrophil adhesion receptor CD18 mediates remote but not localized acid aspiration injury. Surgery. 1995 Jan; 117(1):83-9.
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  55. Klausner JM, Abu-Abid S, Alexander JS, Hanshke-Mineau R, Goldman G, Morel N, Valeri CR, Shepro D, Hechtman HB. Thromboxane modulates endothelial permeability. Mediators Inflamm. 1994; 3(2):149-53.
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  56. Simpson R, Hechtman HB. Pulmonary injury following sepsis. Prog Clin Biol Res. 1994; 388:265-75.
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  57. Simpson R, Alon R, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Neutrophil and nonneutrophil-mediated injury in intestinal ischemia-reperfusion. Ann Surg. 1993 Oct; 218(4):444-53; discussion 453-4.
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  58. Simpson R, Alon R, Valeri CR, Shepro D, Hechtman HB. Integrin dependent neutrophil adhesion following gut ischemia and reperfusion. Behring Inst Mitt. 1993 Aug; (92):210-7.
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  59. Goldman G, Welbourn R, Klausner JM, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Leukocytes mediate acid aspiration-induced multiorgan edema. Surgery. 1993 Jul; 114(1):13-20.
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  60. Wiles ME, Hechtman HB, Morel NM, Shepro D. Hypoxia reoxygenation-induced injury of cultured pulmonary microvessel endothelial cells. J Leukoc Biol. 1993 May; 53(5):490-7.
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  61. Goldman G, Welbourn R, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Lavage with leukotriene B4 induces lung generation of tumor necrosis factor-alpha that in turn mediates neutrophil diapedesis. Surgery. 1993 Mar; 113(3):297-303.
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  62. Mineau-Hanschke R, Patton WF, Hechtman HB, Shepro D. Immunolocalization of cytokeratin 19 in bovine and human pulmonary microvascular endothelial cells in situ. Comp Biochem Physiol Comp Physiol. 1993 Feb; 104(2):313-9.
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  63. Hill J, Lindsay T, Valeri CR, Shepro D, Hechtman HB. A CD18 antibody prevents lung injury but not hypotension after intestinal ischemia-reperfusion. J Appl Physiol. 1993 Feb; 74(2):659-64.
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  64. Lindsay TF, Hill J, Ortiz F, Rudolph A, Valeri CR, Hechtman HB, Moore FD. Blockade of complement activation prevents local and pulmonary albumin leak after lower torso ischemia-reperfusion. Ann Surg. 1992 Dec; 216(6):677-83.
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  65. Hill J, Lindsay TF, Ortiz F, Yeh CG, Hechtman HB, Moore FD. Soluble complement receptor type 1 ameliorates the local and remote organ injury after intestinal ischemia-reperfusion in the rat. J Immunol. 1992 Sep 1; 149(5):1723-8.
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  66. Goldman G, Welbourn R, Klausner JM, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Mast cells and leukotrienes mediate neutrophil sequestration and lung edema after remote ischemia in rodents. Surgery. 1992 Sep; 112(3):578-86.
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  67. Goldman G, Welbourn R, Rothlein R, Wiles M, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Adherent neutrophils mediate permeability after atelectasis. Ann Surg. 1992 Sep; 216(3):372-8; discussion 378-80.
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  68. Hill J, Lindsay T, Rusche J, Valeri CR, Shepro D, Hechtman HB. A Mac-1 antibody reduces liver and lung injury but not neutrophil sequestration after intestinal ischemia-reperfusion. Surgery. 1992 Aug; 112(2):166-72.
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  69. Goldman G, Welbourn R, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Reactive oxygen species and elastase mediate lung permeability after acid aspiration. J Appl Physiol. 1992 Aug; 73(2):571-5.
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  70. Welbourn R, Goldman G, Kobzik L, Paterson IS, Valeri CR, Shepro D, Hechtman HB. Role of neutrophil adherence receptors (CD 18) in lung permeability following lower torso ischemia. Circ Res. 1992 Jul; 71(1):82-6.
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  71. Goldman G, Welbourn R, Klausner JM, Valeri CR, Shepro D, Hechtman HB. Oxygen free radicals are required for ischemia-induced leukotriene B4 synthesis and diapedesis. Surgery. 1992 Mar; 111(3):287-93.
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  72. Goldman G, Welbourn R, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Synergism between leukotriene B4 and thromboxane A2 in mediating acid-aspiration injury. Surgery. 1992 Jan; 111(1):55-61.
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  73. Welbourn R, Goldman G, Kobzik L, Paterson I, Shepro D, Hechtman HB. Interleukin-2 induces early multisystem organ edema mediated by neutrophils. Ann Surg. 1991 Aug; 214(2):181-6.
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  74. Patton WF, Alexander JS, Dodge AB, Patton RJ, Hechtman HB, Shepro D. Mercury-arc photolysis: a method for examining second messenger regulation of endothelial cell monolayer integrity. Anal Biochem. 1991 Jul; 196(1):31-8.
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  75. Welbourn CR, Goldman G, Paterson IS, Valeri CR, Shepro D, Hechtman HB. Pathophysiology of ischaemia reperfusion injury: central role of the neutrophil. Br J Surg. 1991 Jun; 78(6):651-5.
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  76. Wiles ME, Welbourn R, Goldman G, Hechtman HB, Shepro D. Thromboxane-induced neutrophil adhesion to pulmonary microvascular and aortic endothelium is regulated by CD18. Inflammation. 1991 Jun; 15(3):181-99.
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  77. Welbourn R, Goldman G, O'Riordain M, Lindsay TF, Paterson IS, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Role for tumor necrosis factor as mediator of lung injury following lower torso ischemia. J Appl Physiol. 1991 Jun; 70(6):2645-9.
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  78. Welbourn CR, Goldman G, Paterson IS, Valeri CR, Shepro D, Hechtman HB. Neutrophil elastase and oxygen radicals: synergism in lung injury after hindlimb ischemia. Am J Physiol. 1991 Jun; 260(6 Pt 2):H1852-6.
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  79. Goldman G, Welbourn R, Valeri CR, Shepro D, Hechtman HB. Thromboxane A2 induces leukotriene B4 synthesis that in turn mediates neutrophil diapedesis via CD 18 activation. Microvasc Res. 1991 May; 41(3):367-75.
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  80. Goldman G, Welbourn R, Klausner JM, Valeri CR, Shepro D, Hechtman HB. Thromboxane mediates diapedesis after ischemia by activation of neutrophil adhesion receptors interacting with basally expressed intercellular adhesion molecule-1. Circ Res. 1991 Apr; 68(4):1013-9.
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  81. Goldman G, Welbourn R, Alexander S, Klausner JM, Wiles M, Valeri CR, Shepro D, Hechtman HB. Modulation of pulmonary permeability in vivo with agents that affect the cytoskeleton. Surgery. 1991 Apr; 109(4):533-8.
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  82. Goldman G, Welbourn R, Klausner JM, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Neutrophil accumulations due to pulmonary thromboxane synthesis mediate acid aspiration injury. J Appl Physiol. 1991 Apr; 70(4):1511-7.
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  83. Welbourn R, Goldman G, Kobzik L, Valeri CR, Hechtman HB, Shepro D. Attenuation of IL-2-induced multisystem organ edema by phalloidin and antamanide. J Appl Physiol. 1991 Mar; 70(3):1364-8.
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  84. Goldman G, Welbourn R, Klausner JM, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Intravascular chemoattractants inhibit diapedesis by selective receptor occupancy. Am J Physiol. 1991 Feb; 260(2 Pt 2):H465-72.
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  85. Klausner JM, Paterson IS, Goldman G, Kobzik L, Lelcuk S, Skornick Y, Eberlein T, Valeri CR, Shepro D, Hechtman HB. Interleukin-2-induced lung injury is mediated by oxygen free radicals. Surgery. 1991 Feb; 109(2):169-75.
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  86. Dodge AB, Patton WF, Yoon MU, Hechtman HB, Shepro D. Organ and species specific differences in cytoskeletal protein profiles of cultured microvascular endothelial cells. Comp Biochem Physiol B. 1991; 98(4):461-70.
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  87. Dodge AB, Hechtman HB, Shepro D. Microvascular endothelial-derived autacoids regulate pericyte contractility. Cell Motil Cytoskeleton. 1991; 18(3):180-8.
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  88. Klausner JM, Goldman G, Skornick Y, Valeri R, Inbar M, Shepro D, Hechtman HB. Interleukin-2-induced lung permeability is mediated by leukotriene B4. Cancer. 1990 Dec 1; 66(11):2357-64.
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  89. Welbourn R, Goldman G, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Involvement of thromboxane and neutrophils in multiple-system organ edema with interleukin-2. Ann Surg. 1990 Dec; 212(6):728-33.
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  90. Goldman G, Welbourn R, Klausner JM, Alexander S, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Attenuation of acid aspiration edema with phalloidin. Am J Physiol. 1990 Dec; 259(6 Pt 1):L378-83.
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  91. Morel NM, Petruzzo PP, Hechtman HB, Shepro D. Inflammatory agonists that increase microvascular permeability in vivo stimulate cultured pulmonary microvessel endothelial cell contraction. Inflammation. 1990 Oct; 14(5):571-83.
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  92. Goldman G, Welbourn R, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Tumor necrosis factor-alpha mediates acid aspiration-induced systemic organ injury. Ann Surg. 1990 Oct; 212(4):513-9; discussion 519-20.
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  93. Welbourn R, Goldman G, Kobzik L, Paterson I, Valeri CR, Shepro D, Hechtman HB. Neutrophil adherence receptors (CD 18) in ischemia. Dissociation between quantitative cell surface expression and diapedesis mediated by leukotriene B4. J Immunol. 1990 Sep 15; 145(6):1906-11.
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  94. Patton WF, Yoon MU, Alexander JS, Chung-Welch N, Hechtman HB, Shepro D. Expression of simple epithelial cytokeratins in bovine pulmonary microvascular endothelial cells. J Cell Physiol. 1990 Apr; 143(1):140-9.
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  95. Goldman G, Welbourn R, Paterson IS, Klausner JM, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Ischemia-induced neutrophil activation and diapedesis is lipoxygenase dependent. Surgery. 1990 Apr; 107(4):428-33.
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  96. Mineau-Hanschke R, Wiles ME, Morel N, Hechtman HB, Shepro D. Modulation of cultured pulmonary microvessel and arterial endothelial cell barrier structure and function by serotonin. Microvasc Res. 1990 Mar; 39(2):140-55.
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  97. Goldman G, Welbourn R, Klausner JM, Paterson IS, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Ischemia activates neutrophils but inhibits their local and remote diapedesis. Ann Surg. 1990 Feb; 211(2):196-201.
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  98. Paterson IS, Klausner JM, Goldman G, Pugatch R, Feingold H, Allen P, Mannick JA, Valeri CR, Shepro D, Hechtman HB. Pulmonary edema after aneurysm surgery is modified by mannitol. Ann Surg. 1989 Dec; 210(6):796-801.
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  99. Morel NM, Dodge AB, Patton WF, Herman IM, Hechtman HB, Shepro D. Pulmonary microvascular endothelial cell contractility on silicone rubber substrate. J Cell Physiol. 1989 Dec; 141(3):653-9.
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  100. Chung-Welch N, Patton WF, Yen-Patton GP, Hechtman HB, Shepro D. Phenotypic comparison between mesothelial and microvascular endothelial cell lineages using conventional endothelial cell markers, cytoskeletal protein markers and in vitro assays of angiogenic potential. Differentiation. 1989 Oct; 42(1):44-53.
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  101. Paterson IS, Klausner JM, Goldman G, Kobzik L, Welbourn R, Valeri CR, Shepro D, Hechtman HB. Thromboxane mediates the ischemia-induced neutrophil oxidative burst. Surgery. 1989 Aug; 106(2):224-9.
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  102. Klausner JM, Paterson IS, Morel NM, Goldman G, Gray AD, Valeri R, Eberlein TJ, Shepro D, Hechtman HB. Role of thromboxane in interleukin 2-induced lung injury in sheep. Cancer Res. 1989 Jul 1; 49(13):3542-9.
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  103. Paterson IS, Klausner JM, Goldman G, Welbourn R, Alexander JS, Shepro D, Hechtman HB. The endothelial cell cytoskeleton modulates extravascular polymorphonuclear leukocyte accumulations in vivo. Microvasc Res. 1989 Jul; 38(1):49-56.
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  104. Klausner JM, Paterson IS, Goldman G, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Thromboxane A2 mediates increased pulmonary microvascular permeability following limb ischemia. Circ Res. 1989 Jun; 64(6):1178-89.
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  105. Klausner JM, Paterson IS, Goldman G, Kobzik L, Rodzen C, Lawrence R, Valeri CR, Shepro D, Hechtman HB. Postischemic renal injury is mediated by neutrophils and leukotrienes. Am J Physiol. 1989 May; 256(5 Pt 2):F794-802.
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  106. Klausner JM, Paterson IS, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Leukotrienes but not complement mediate limb ischemia-induced lung injury. Ann Surg. 1989 Apr; 209(4):462-70.
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  107. Doukas J, Hechtman HB, Shepro D. Vasoactive amines and eicosanoids interactively regulate both polymorphonuclear leukocyte diapedesis and albumin permeability in vitro. Microvasc Res. 1989 Mar; 37(2):125-37.
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  108. Klausner JM, Paterson IS, Mannick JA, Valeri R, Shepro D, Hechtman HB. Reperfusion pulmonary edema. JAMA. 1989 Feb 17; 261(7):1030-5.
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  109. Klausner JM, Paterson IS, Kobzik L, Rodzen C, Valeri CR, Shepro D, Hechtman HB. Vasodilating prostaglandins attenuate ischemic renal injury only if thromboxane is inhibited. Ann Surg. 1989 Feb; 209(2):219-24.
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  110. Dubose DA, Shepro D, Hechtman HB. Modulation of phospholipase A2 lytic activity by actin and myosin. Inflammation. 1989 Feb; 13(1):15-29.
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  111. Klausner JM, Paterson IS, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Oxygen free radicals mediate ischemia-induced lung injury. Surgery. 1989 Feb; 105(2 Pt 1):192-9.
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  112. Paterson IS, Klausner JM, Pugatch R, Allen P, Mannick JA, Shepro D, Hechtman HB. Noncardiogenic pulmonary edema after abdominal aortic aneurysm surgery. Ann Surg. 1989 Feb; 209(2):231-6.
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  113. Klausner JM, Morel N, Paterson IS, Kobzik L, Valeri CR, Eberlein TJ, Shepro D, Hechtman HB. The rapid induction by interleukin-2 of pulmonary microvascular permeability. Ann Surg. 1989 Jan; 209(1):119-28.
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  114. Mineau-Hanschke R, Hechtman HB, Shepro D. Endothelial cell junctional integrity modulation by serotonin: an ultrastructural analysis. Tissue Cell. 1989; 21(2):161-70.
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  115. Klausner JM, Paterson IS, Valeri CR, Shepro D, Hechtman HB. Limb ischemia-induced increase in permeability is mediated by leukocytes and leukotrienes. Ann Surg. 1988 Dec; 208(6):755-60.
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  116. Klausner JM, Anner H, Paterson IS, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Lower torso ischemia-induced lung injury is leukocyte dependent. Ann Surg. 1988 Dec; 208(6):761-7.
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  117. Klausner JM, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Selective lung leukosequestration after complement activation. J Appl Physiol. 1988 Jul; 65(1):80-8.
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  118. Huval WV, Lelcuk S, Feingold H, Valeri CR, Shepro D, Hechtman HB. Effects of nitroprusside and ketanserin upon pulmonary edema after acid injury. Surg Gynecol Obstet. 1988 Jun; 166(6):527-34.
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  119. Anner H, Kaufman RP, Valeri CR, Shepro D, Hechtman HB. Reperfusion of ischemic lower limbs increases pulmonary microvascular permeability. J Trauma. 1988 May; 28(5):607-10.
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  120. Alexander JS, Hechtman HB, Shepro D. Phalloidin enhances endothelial barrier function and reduces inflammatory permeability in vitro. Microvasc Res. 1988 May; 35(3):308-15.
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  121. Chung-Welch N, Shepro D, Dunham B, Hechtman HB. Prostacyclin and prostaglandin E2 secretions by bovine pulmonary microvessel endothelial cells are altered by changes in culture conditions. J Cell Physiol. 1988 May; 135(2):224-34.
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  122. Kelley C, D'Amore P, Hechtman HB, Shepro D. Vasoactive hormones and cAMP affect pericyte contraction and stress fibres in vitro. J Muscle Res Cell Motil. 1988 Apr; 9(2):184-94.
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  123. Kaufman RP, Klausner JM, Anner H, Feingold H, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Inhibition of thromboxane (Tx) synthesis by free radical scavengers. J Trauma. 1988 Apr; 28(4):458-64.
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  124. Austin JC, Berrizbeitia LD, Schoen FJ, Kauffman RP, Hechtman HB, Cohn LH. Thromboxane synthetase inhibition reduces ventricular irritability after coronary occlusion and reperfusion. Am Heart J. 1988 Mar; 115(3):505-9.
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  125. Doukas J, Hechtman HB, Shepro D. Endothelial-secreted arachidonic acid metabolites modulate polymorphonuclear leukocyte chemotaxis and diapedesis in vitro. Blood. 1988 Mar; 71(3):771-9.
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  126. Klausner JM, Caspi J, Lelcuk S, Khazam A, Marin G, Hechtman HB, Rozin RR. Delayed muscular rigidity and respiratory depression following fentanyl anesthesia. Arch Surg. 1988 Jan; 123(1):66-7.
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  127. Anner H, Kaufman RP, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Pulmonary hypertension and leukosequestration after lower torso ischemia. Ann Surg. 1987 Nov; 206(5):642-8.
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  128. Kaufman RP, Anner H, Kobzik L, Valeri CR, Shepro D, Hechtman HB. A high plasma prostaglandin to thromboxane ratio protects against renal ischemia. Surg Gynecol Obstet. 1987 Nov; 165(5):404-9.
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  129. Anner H, Kaufman RP, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Pulmonary leukosequestration induced by hind limb ischemia. Ann Surg. 1987 Aug; 206(2):162-7.
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  130. Doukas J, Shepro D, Hechtman HB. Vasoactive amines directly modify endothelial cells to affect polymorphonuclear leukocyte diapedesis in vitro. Blood. 1987 Jun; 69(6):1563-9.
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  131. Kelley C, D'Amore P, Hechtman HB, Shepro D. Microvascular pericyte contractility in vitro: comparison with other cells of the vascular wall. J Cell Biol. 1987 Mar; 104(3):483-90.
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  132. Alexander JS, Hechtman HB, Shepro D. Serotonin induced actin polymerization and association with cytoskeletal elements in cultured bovine aortic endothelium. Biochem Biophys Res Commun. 1987 Feb 27; 143(1):152-8.
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  133. Dubose DA, Shepro D, Hechtman HB. Correlation among endothelial cell shape, F-actin arrangement, and prostacyclin synthesis. Life Sci. 1987 Feb 2; 40(5):447-53.
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  134. Kaufman RP, Anner H, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Vasodilator prostaglandins (PG) prevent renal damage after ischemia. Ann Surg. 1987 Feb; 205(2):195-8.
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  135. Alexander F, Manny J, Lelcuk S, Shepro D, Hechtman HB. Cyclo-oxygenase products mediate hypoxic pulmonary hypertension. J Pediatr Surg. 1986 Dec; 21(12):1101-7.
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  136. Lelcuk S, Threlfall L, Valeri CR, Shepro D, Hechtman HB. Nicotine stimulates pulmonary parenchymal thromboxane synthesis. Surgery. 1986 Nov; 100(5):836-40.
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  137. Bottaro D, Shepro D, Hechtman HB. Heterogeneity of intimal and microvessel endothelial cell barriers in vitro. Microvasc Res. 1986 Nov; 32(3):389-98.
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  138. Bottaro D, Shepro D, Peterson S, Hechtman HB. Serotonin, norepinephrine, and histamine mediation of endothelial cell barrier function in vitro. J Cell Physiol. 1986 Aug; 128(2):189-94.
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  139. Demling RH, Wenger H, Lalonde CC, Hechtman H, Wong C, West K. Endotoxin-induced prostanoid production by the burn wound can cause distant lung dysfunction. Surgery. 1986 Apr; 99(4):421-31.
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  140. Manny J, Manny N, Lelcuk S, Alexander F, Feingold H, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Pulmonary and systemic consequences of localized acid aspiration. Surg Gynecol Obstet. 1986 Mar; 162(3):259-67.
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  141. Palder SB, Huval W, Lelcuk S, Alexander F, Shepro D, Mannick JA, Hechtman HB. Reduction of polymorphonuclear leukocyte accumulations by inhibition of cyclooxygenase and thromboxane syntase in the rabbit. Surgery. 1986 Jan; 99(1):72-81.
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  142. Demling RH, Wong C, Fox R, Hechtman H, Huval W. Relationship of increased lung serotonin levels to endotoxin-induced pulmonary hypertension in sheep. Effect of a serotonin antagonist. Am Rev Respir Dis. 1985 Dec; 132(6):1257-61.
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  143. Welles SL, Shepro D, Hechtman HB. Eicosanoid modulation of stress fibers in cultured bovine aortic endothelial cells. Inflammation. 1985 Dec; 9(4):439-50.
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  144. Lelcuk S, Alexander F, Valeri CR, Shepro D, Hechtman HB. Thromboxane A2 moderates permeability after limb ischemia. Ann Surg. 1985 Nov; 202(5):642-6.
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  145. Demling RH, Wong C, Jin LJ, Hechtman H, Lalonde C, West K. Early lung dysfunction after major burns: role of edema and vasoactive mediators. J Trauma. 1985 Oct; 25(10):959-66.
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  146. Lelcuk S, Alexander F, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Prostacyclin and thromboxane A2 moderate postischemic renal failure. Surgery. 1985 Aug; 98(2):207-12.
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  147. Shepro D, Hechtman HB. Endothelial serotonin uptake and mediation of prostanoid secretion and stress fiber formation. Fed Proc. 1985 Jul; 44(10):2616-9.
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  148. Welles SL, Shepro D, Hechtman HB. Vasoactive amines modulate actin cables (stress fibers) and surface area in cultured bovine endothelium. J Cell Physiol. 1985 Jun; 123(3):337-42.
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  149. Bottaro D, Shepro D, Peterson S, Hechtman HB. Serotonin, histamine, and norepinephrine mediation of endothelial and vascular smooth muscle cell movement. Am J Physiol. 1985 Mar; 248(3 Pt 1):C252-7.
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  150. Demling RH, Wenger H, Hechtman H, Wong C. Role of subcutaneous tissue endotoxin in the production of prostanoid-induced lung injury: comparison with intravenous endotoxin response. Circ Shock. 1985; 17(2):147-61.
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  151. DiSesa VJ, Huval W, Lelcuk S, Jonas R, Maddi R, Lee-Son S, Shemin RJ, Collins JJ, Hechtman HB, Cohn LH. Disadvantages of prostacyclin infusion during cardiopulmonary bypass: a double-blind study of 50 patients having coronary revascularization. Ann Thorac Surg. 1984 Nov; 38(5):514-9.
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  152. Hechtman HB, Valeri CR, Shepro D. Role of humoral mediators in adult respiratory distress syndrome. Chest. 1984 Oct; 86(4):623-7.
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  153. Dunham B, Shepro D, Hechtman HB. Leukotriene induction of TxB2 in cultured bovine aortic endothelial cells. Inflammation. 1984 Sep; 8(3):313-21.
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  154. Shepro D, Welles SL, Hechtman HB. Vasoactive agonists prevent erythrocyte extravasation in thrombocytopenic hamsters. Thromb Res. 1984 Aug 15; 35(4):421-30.
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  155. Alexander F, Mathieson M, Teoh KH, Huval WV, Lelcuk S, Valeri CR, Shepro D, Hechtman HB. Arachidonic acid metabolites mediate early burn edema. J Trauma. 1984 Aug; 24(8):709-12.
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  156. Dunham BM, Hechtman HB, Valeri CR, Shepro D. Antiinflammatory agents inhibit microvascular permeability induced by leukotrienes and by stimulated human neutrophils. Microcirc Endothelium Lymphatics. 1984 Aug; 1(4):465-89.
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  157. Huval WV, Lelcuk S, Shepro D, Hechtman HB. Role of serotonin in patients with acute respiratory failure. Ann Surg. 1984 Aug; 200(2):166-72.
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  158. Lelcuk S, Huval WV, Valeri CR, Shepro D, Hechtman HB. Inhibition of ischemia-induced thromboxane synthesis in man. J Trauma. 1984 May; 24(5):393-6.
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  159. Huval WV, Lelcuk S, Allen PD, Mannick JA, Shepro D, Hechtman HB. Determinants of cardiovascular stability during abdominal aortic aneurysmectomy (AAA). Ann Surg. 1984 Feb; 199(2):216-22.
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  160. Wong C, Huval W, Hechtman H, Demling RH. Effect of hemorrhagic shock on endotoxin-induced pulmonary hypertension and increased vascular permeability in unanesthetized sheep. Circ Shock. 1984; 12(1):61-71.
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  161. Mathieson MA, Dunham BM, Huval WV, Lelcuk S, Stemp LI, Valeri CR, Shepro D, Hechtman HB. Ischemia of the limb stimulates thromboxane production and myocardial depression. Surg Gynecol Obstet. 1983 Dec; 157(6):500-4.
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  162. Huval WV, Dunham BM, Lelcuk S, Valeri CR, Shepro D, Hechtman HB. Thromboxane mediation of cardiovascular dysfunction following aspiration. Surgery. 1983 Aug; 94(2):259-66.
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  163. Hechtman HB, Huval WV, Mathieson MA, Stemp LI, Valeri CR, Shepro D. Prostaglandin and thromboxane mediation of cardiopulmonary failure. Surg Clin North Am. 1983 Apr; 63(2):263-83.
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  164. Aznavoorian SA, Utsunomiya T, Krausz MM, Cohn LH, Shepro D, Hechtman HB. Prostacyclin inhibits 5-hydroxytryptamine release but stimulates thromboxane synthesis during cardiopulmonary bypass. Prostaglandins. 1983 Apr; 25(4):557-70.
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  165. Krausz MM, Utsunomiya T, McIrvine AJ, Allen PD, Levine L, Mannick JA, Shepro D, Hechtman HB. Modulation of cardiovascular function and platelet survival by endogenous prostacyclin released during surgery. Surgery. 1983 Apr; 93(4):554-9.
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  166. Krausz MM, Utsunomiya T, Valeri CR, Hechtman HB. One-stage technique for chronic hemodynamic and lung-lymphatic cannulation in sheep. Isr J Med Sci. 1983 Feb; 19(2):199-201.
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  167. Kripke BJ, Justice RE, Hechtman HB. Postoperative nitrous oxide analgesia and the functional residual capacity. Crit Care Med. 1983 Feb; 11(2):105-9.
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  168. Huval WV, Mathieson MA, Stemp LI, Dunham BM, Jones AG, Shepro D, Hechtman HB. Therapeutic benefits of 5-hydroxytryptamine inhibition following pulmonary embolism. Ann Surg. 1983 Feb; 197(2):220-5.
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  169. Utsunomiya T, Krausz MM, Dunham B, Valeri CR, Levine L, Shepro D, Hechtman HB. Modification of inflammatory response to aspiration with ibuprofen. Am J Physiol. 1982 Dec; 243(6):H903-10.
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  170. Justice RE, Kripke BJ, Hechtman HB. Helium meter correction equations for oxygen and nitrous oxide. Crit Care Med. 1982 Dec; 10(12):876-9.
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  171. Krausz MM, Utsunomiya T, Dunham B, Valeri CR, Shepro D, Hechtman HB. Inhibition of permeability edema with imidazole. Surgery. 1982 Aug; 92(2):299-308.
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  172. Utsonomiya T, Krausz MM, Levine L, Shepro D, Hechtman HB. Thromboxane mediation of cardiopulmonary effects of embolism. J Clin Invest. 1982 Aug; 70(2):361-8.
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  173. Grindlinger GA, Utsunomiya T, Vegas A, Levine LL, Shepro D, Hechtman HB. Prostaglandin mediation of unstable hemodynamics during lung perfusion. Surgery. 1982 Jul; 92(1):52-60.
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  174. Utsunomiya T, Krausz MM, Kobayashi M, Shepro D, Hechtman HB. Myocardial protection with prostacyclin after lethal endotoxemia. Surgery. 1982 Jul; 92(1):101-8.
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  175. Krausz MM, Utsunomiya T, Levine LL, Dunham B, Shepro D, Hechtman HB. Adverse effects of prostacyclin used to perfuse isolated lung lobes. Am J Physiol. 1982 May; 242(5):H745-50.
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  176. Utsunomiya T, Krausz MK, Dunham B, Levine L, Shepro D, Hechtman HB. Circulating negative inotropic agent(s) following pulmonary embolism. Surgery. 1982 Apr; 91(4):402-8.
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  177. Utsunomiya T, Krausz MM, Dunham B, Shepro D, Hechtman HB. Depression of myocardial ATPase activity by plasma obtained during positive end-expiratory pressure. Surgery. 1982 Mar; 91(3):322-8.
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  178. Justice RE, Utsunomiya T, Krausz MM, Valeri CR, Shepro D, Hechtman HB. A miniaturized chamber for the measure of oxygen consumption. J Appl Physiol. 1982 Feb; 52(2):488-90.
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  179. Hechtman HB, Shepro D. Lung metabolism and systemic organ function. Circ Shock. 1982; 9(4):457-67.
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  180. Dunham BM, Grindlinger GA, Utsunomiya T, Krausz MM, Hechtman HB, Shepro D. Role of prostaglandins in positive end-expiratory pressure-induced negative inotropism. Am J Physiol. 1981 Dec; 241(6):H783-8.
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  181. Utsunomiya T, Krausz MM, Shepro D, Hechtman HB. Prostaglandin control of plasma and platelet 5-hydroxytryptamine in normal and embolized animals. Am J Physiol. 1981 Nov; 241(5):H766-71.
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  182. Utsunomiya T, Krausz MM, Dunham B, Mannick JA, Allen PD, Shepro D, Hechtman HB. Maintenance of cardiodynamics with aspirin during abdominal aortic aneurysmectomy (AAA). Ann Surg. 1981 Nov; 194(5):602-8.
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  183. Krausz MM, Dennis RC, Utsunomiya T, Grindlinger GA, Vegas AM, Churchill WH, Mannick JA, Valeri CR, Hechtman HB. Cardiopulmonary function following transfusion of three red blood cell products in elective abdominal aortic aneurysmectomy. Ann Surg. 1981 Nov; 194(5):616-24.
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  184. Utsunomiya T, Krausz MM, Shepro D, Hechtman HB. Induction of myocardial damage with nitroprusside. J Surg Res. 1981 Sep; 31(3):195-200.
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  185. Utsunomiya T, Krausz MM, Valeri CR, Shepro D, Hechtman HB. Treatment of aspiration pneumonia with ibuprofen and prostacyclin. Surgery. 1981 Aug; 90(2):170-6.
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  186. Koshal A, Krausz MM, Utsunomiya T, Hechtman HB, Collins JJ, Cohn LH. Preservation of platelets and their function in prolonged cardiopulmonary bypass using prostacyclin. Circulation. 1981 Aug; 64(2 Pt 2):II44-8.
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  187. Utsunomiya T, Krausz MM, Valeri CR, Levine L, Shepro D, Hechtman HB. Treatment of pulmonary embolism with positive end-expiratory pressure and prostaglandin E1. Surg Gynecol Obstet. 1981 Aug; 153(2):161-8.
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  188. Grindlinger GA, Vegas AM, Williams GH, Mannick JA, Hechtman HB. Independence of renin production and hypertension in abdominal aortic aneurysmectomy. Am J Surg. 1981 Apr; 141(4):472-7.
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  189. Krausz MM, Utsunomiya T, Feuerstein G, Wolfe JH, Shepro D, Hechtman HB. Prostacyclin reversal of lethal endotoxemia in dogs. J Clin Invest. 1981 Apr; 67(4):1118-25.
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  190. Krausz MM, Manny J, Utsunomiya T, Hechtman HB. Peritoneal lavage in blunt abdominal trauma. Surg Gynecol Obstet. 1981 Mar; 152(3):327-30.
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  191. Sweetman HE, Shepro D, Hechtman HB. Inhibition of thrombocytopenic petechiae by exogenous serotonin administration. Haemostasis. 1981; 10(2):65-78.
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  192. Hechtman HB, Utsunomiya T, Krausz MM, Shepro D. The management of cardiorespiratory failure in surgical patients. Adv Surg. 1981; 15:123-56.
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  193. Robinson-White A, Peterson S, Hechtman HB, Shepro D. Serotonin uptake by isolated adipose capillary endothelium. J Pharmacol Exp Ther. 1981 Jan; 216(1):125-8.
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  194. Krausz MM, Justice RE, Utsunomiya T, Hechtman HB. A cooling system for prostaglandin infusions. Ann Biomed Eng. 1981; 9(3):257-62.
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  195. Hechtman HB, Krausz MM, Utsunomiya T, Valeri CR. Preoperative assessment of the high risk surgical patient. Surg Clin North Am. 1980 Dec; 60(6):1349-58.
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  196. Valeri CR, Yarnoz M, Vecchione JJ, Dennis RC, Anastasi J, Valeri DA, Pivacek LE, Hechtman HB, Emerson CP, Berger RL. Improved oxygen delivery to the myocardium during hypothermia by perfusion with 2,3 DPG-enriched red blood cells. Ann Thorac Surg. 1980 Dec; 30(6):527-35.
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  197. Shepro D, Sweetman HE, Hechtman HB. Experimental thrombocytopenia and capillary ultrastructure. Blood. 1980 Nov; 56(5):937-9.
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  198. Whittemore AD, Clowes AW, Hechtman HB, Mannick JA. Aortic aneurysm repair. Reduced operative mortality associated with maintenance of optimal cardiac performance. Ann Surg. 1980 Sep; 192(3):414-21.
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  199. Dennis RC, Harlow C, Egdahl RH, Hechtman HB. Enhancement of myocardial function with glucose, insulin and potassium. Surg Gynecol Obstet. 1980 Aug; 151(2):185-90.
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  200. Grindlinger GA, Vegas AM, Churchill WH, Valeri CR, Hechtman HB. Is respiratory failure a consequence of blood transfusion? J Trauma. 1980 Aug; 20(8):627-31.
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  201. Hechtman HB, Vegas AM, Grindlinger GA. Diagnosis and treatment of acute respiratory failure. R I Med J. 1980 Jul; 63(7):249-54.
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  202. Utsunomiya T, Krausz MM, Valeri CR, Shepro D, Hechtman HB. Treatment of pulmonary embolism with prostacyclin. Surgery. 1980 Jul; 88(1):25-30.
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  203. Shepro D, Li S, Hechtman HB. Plasminogen activator activity of isolated cardiac muscle microvessel endothelial cells. Thromb Res. 1980 Jun 1; 18(5):609-16.
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  204. Grindlinger GA, Vegas AM, Manny J, Bush HL, Mannick JA, Hechtman HB. Volume loading and vasodilators in abdominal aortic aneurysmectomy. Am J Surg. 1980 Apr; 139(4):480-6.
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  205. Shepro D, Schleef R, Hechtman HB. Plasminogen activator activity by cultured bovine aortic endothelial cells. Life Sci. 1980 Feb 11; 26(6):415-22.
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  206. McLoughlin GA, Manny J, Grindlinger GA, Hechtman HB. Pressure breathing and altered fibrinolytic activity. Ann Thorac Surg. 1980 Feb; 29(2):156-65.
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  207. Manny J, Grindlinger GA, Dennis RC, Weisel RD, Hechtman HB. Myocardial performance curves as guide to volume therapy. Surg Gynecol Obstet. 1979 Dec; 149(6):863-73.
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  208. McLoughlin GA, Grindlinger GA, Manny J, Valeri CR, Lipinski B, Mannick JA, Hechtman HB. Intrapulmonary clotting and fibrinolysis during abdominal aortic aneurysm surgery. Ann Surg. 1979 Nov; 190(5):623-30.
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  209. Grindlinger GA, Manny J, Justice R, Dunham B, Shepro D, Hechtman HB. Presence of negative inotropic agents in canine plasma during positive end-expiratory pressure. Circ Res. 1979 Oct; 45(4):460-7.
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  210. Hechtman HB, Grindlinger GA, Vegas AM, Manny J, Valeri CR. Importance of oxygen transport in clinical medicine. Crit Care Med. 1979 Sep; 7(9):419-23.
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  211. Justice R, Grindlinger GA, Shepro D, Hechtman HB. A new papillary muscle chamber to test small plasma volumes. Microvasc Res. 1979 Jul; 18(1):120-3.
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  212. Manny J, Justice R, Hechtman HB. Left ventricular filling pressure as a determinant of subendocardial blood flow. Ann Thorac Surg. 1979 May; 27(5):451-9.
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  213. Manny J, Justice R, Hechtman HB. Abnormalities in organ blood flow and its distribution during positive end-expiratory pressure. Surgery. 1979 Apr; 85(4):425-32.
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  214. Manny J, Hechtman HB. Coronary autoregulation and the descending Starling limb in critical illness. Bibl Anat. 1979; (18):259-61.
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  215. Vegas AM, Grindlinger GA, McLoughlin GA, Hechtman HB. Control of pulmonary fibrinolytic activity by prostaglandins. Surg Forum. 1979; 30:180-1.
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  216. Grindlinger GA, Vegas AM, Manny J, Hechtman HB. Prostaglandin-mediated decreases in contractility during PEEP. Surg Forum. 1979; 30:163-4.
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  217. Hechtman HB, Manny J, Valeri CR, Shepro D. Optimization of oxygen transport in acute respiratory failure. Bibl Anat. 1979; (18):164-5.
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  218. Shepro D, Robinson A, Hechtman HB. Serotonin clearance by capillaries isolated from epididymal fat. Bibl Anat. 1979; (18):108-10.
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  219. Manny J, Rabinovici N, Manny N, Schiller M, Hechtman HB. Effect of glucose-insulin-postassium on survival in experimental endotoxic shock. Surg Gynecol Obstet. 1978 Sep; 147(3):405-9.
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  220. Patten MT, Liebman PR, Manny J, Shepro D, Hechtman HB. Humorally mediated alterations in cardiac performance as a consequence of positive end-expiratory pressure. Surgery. 1978 Aug; 84(2):201-5.
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  221. Dennis RC, Hechtman HB, Berger RL, Vito L, Weisel RD, Valeri CR. Transfusion of 2,3 DPG-enriched red blood cells to improve cardiac function. Ann Thorac Surg. 1978 Jul; 26(1):17-6.
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  222. Manny J, Grindlinger G, Mathé AA, Hechtman HB. Positive end-expiratory pressure, lung stretch, and decreased myocardial contractility. Surgery. 1978 Jul; 84(1):127-33.
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  223. Weisel RD, Dennis RC, Manny J, Mannick JA, Valeri CR, Hechtman HB. Adverse effects of transfusion therapy during abdominal aortic aneurysectomy. Surgery. 1978 Jun; 83(6):682-90.
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  224. Liebman PR, Philips E, Weisel R, Ali J, Hechtman HB. Limitations of portable roentgenography of the chest in patients with acute respiratory failure. Surg Gynecol Obstet. 1978 May; 146(5):705-8.
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  225. Liebman PR, Patten MT, Manny J, Shepro D, Hechtman HB. The mechanism of depressed cardiac output on positive end-expiratory pressure (PEEP). Surgery. 1978 May; 83(5):594-8.
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  226. D'Amore PA, Hechtman HB, Shepro D. Ornithine decarboxylase activity in cultured endothelial cells stimulated by serum, thrombin and serotonin. Thromb Haemost. 1978 Apr 30; 39(2):496-503.
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  227. Liebman PR, Philips E, Weisel R, Ali J, Hechtman HB. Diagnostic value of the portable chest x-ray technic in pulmonary edema. Am J Surg. 1978 Apr; 135(4):604-6.
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  228. Liebman PR, Patten MT, Manny J, Benfield JR, Hechtman HB. Hepatic--portal venous gas in adults: etiology, pathophysiology and clinical significance. Ann Surg. 1978 Mar; 187(3):281-7.
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  229. Hechtman HB, Lonergan EA, Staunton HP, Dennis RC, Shepro D. Pulmonary entrapment of platelets during acute respiratory failure. Surgery. 1978 Mar; 83(3):277-83.
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  230. Manny J, Patten MT, Liebman PR, Hechtman HB. The association of lung distention, PEEP and biventricular failure. Ann Surg. 1978 Feb; 187(2):151-7.
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  231. Liebman PR, Patten MT, Hechtman HB. A method for direct coronary sinus flow measurement and blood sampling in the dog. Ann Thorac Surg. 1978 Feb; 25(2):155-7.
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  232. Hechtman HB, Lonergan EA, Shepro D. Platelet and leukocyte lung interactions in patients with respiratory failure. Surgery. 1978 Feb; 83(2):155-63.
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  233. Valeri CR, Weisel RD, Dennis RC, Mannick JA, Berger RL, Hechtman HB. Oxygen transport function of preserved red blood cells and myocardial performance. Prog Clin Biol Res. 1978; 21:597-616.
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  234. Grindlinger GA, Manny J, Weisel RD, Bush HL, Mannick JA, Hechtman HB. Volume loading and nitroprusside in abdominal aortic aneurysectomy. Surg Forum. 1978; 29:234-6.
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  235. Manny J, Justice RE, Hechtman HB. Maldistribution of blood flow during positive end expiratory pressure. Surg Forum. 1978; 29:203-5.
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  236. McLoughlin GA, Manny J, Grindlinger GA, Hechtman HB. Induction of fibrinolytic activity by pressure breathing. Surg Forum. 1978; 29:201-3.
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  237. Bush HL, LoGerfo FW, Weisel RD, Mannick JA, Hechtman HB. Assessment of myocardial performance and optimal volume loading during elective abdominal aortic aneurysm resection. Arch Surg. 1977 Nov; 112(11):1301-5.
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  238. Weisel RD, Vito L, Dennis RC, Valeri CR, Hechtman HB. Myocardial depression during sepsis. Am J Surg. 1977 Apr; 133(4):512-21.
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  239. Manny J, Schiller M, Manny N, Rabinovici N, Hechtman HB. Beneficial effects of glucose-insulin-potassium following endotoxemia. Surg Forum. 1977; 28:88-90.
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  240. Hechtman HB, Weisel RD, Vito L, Dennis RC, Mannick JA. Acute pulmonary insufficiency following abdominal aortic aneurysm repair. Bibl Anat. 1977; (15 Pt 1):436-8.
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  241. Hechtman HB. Adequate circulatory responses or cardiovascular failure. Surg Clin North Am. 1976 Aug; 56(4):929-43.
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  242. Berger RL, Weisel RD, Vito L, Dennis RC, Hechtman HB. Cardiac output measurement by thermodilution during cardiac operations. Ann Thorac Surg. 1976 Jan; 21(1):43-7.
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  243. Liebman PR, Patten MT, Dennis RC, Chang KW, Aisenberg S, Hechtman HB. Continuous monitoring of in vivo oxygen tension with a fuel cell. Surg Forum. 1976; 27(62):58-9.
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  244. Saini VK, Hood WB, Hechtman HB, Berger RL. Nutrient myocardial blood flow in experimental myocardial ischemia. Effects of intraaortic balloon counterpulsation and coronary reperfusion. Circulation. 1975 Dec; 52(6):1086-90.
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  245. Shepro D, Hechtman HB, Belamarich FA. Proceedings: Endothelium and serotonin transport. Thromb Diath Haemorrh. 1975 Sep 30; 34(1):329.
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  246. Mackay S, Hechtman HB. Continuous cardiac output measurement: aspects of Doppler frequency analysis. IEEE Trans Biomed Eng. 1975 Jul; 22(4):346-50.
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  247. Ali J, Weisel R, Layug A, Kripke B, Hechtman HB. Spirometry and the mechanisms of pulmonary complications following elective surgery. Int Surg. 1975 Jun-Jul; 60(6-7):343-7.
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  248. Dennis RC, Vito L, Weisel RD, Valeri CR, Berger RL, Hechtman HB. Improved myocardial performance following high 2-3 diphosphoglycerate red cell transfusions. Surgery. 1975 Jun; 77(6):741-7.
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  249. Foster ED, Subramanian VA, Hechtman HB, Berger RL, Vito L. Response to intra-aortic balloon pumping. Am J Surg. 1975 Apr; 129(4):464-71.
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  250. Weisel RD, Vito L, Dennis RC, Berger RL, Hechtman HB. Clinical applications of thermodilution cardiac output determinations. Am J Surg. 1975 Apr; 129(4):449-54.
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  251. Dwight RW, Schimmel EM, O'Hara ET, Hechtman HB, Williams LF, Vollman RW, Maselli JP, Johnson WC, Nabseth DC. Controlled study of the surgical treatment of duodenal ulcer. Am J Surg. 1975 Apr; 129(4):374-9.
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  252. Weisel RD, Berger RL, Hechtman HB. Current concepts measurement of cardiac output by thermodilution. N Engl J Med. 1975 Mar 27; 292(13):682-4.
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  253. White MK, Hechtman HB, Shepro D. Canine lung uptake of plasma and platelet serotonin. Microvasc Res. 1975 Mar; 9(2):230-41.
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  254. Berger RL, Ryan TJ, Hechtman HB, Saini VK, Foster ED. Applications of intra-aortic balloon counterpulsation. Isr J Med Sci. 1975 Feb-Mar; 11(2-3):231-8.
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  255. Dennis RC, Vito L, Hechtman HB. Pulmonary insufficiency following Escherichia coli bacteremia in dogs. Surg Forum. 1975; 26:202-4.
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  256. Ali J, Weisel RD, Layug AB, Kripke BJ, Hechtman HB. Consequences of postoperative alterations in respiratory mechanics. Am J Surg. 1974 Sep; 128(3):376-82.
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  257. Reid MH, Hechtman HB. A multicompartment analysis of the lung. Med Biol Eng. 1974 Jul; 12(4):405-14.
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  258. Hechtman HB, Reid MH. A discussion of some single-compartment systems using intravascular tracers for the estimation of respiratory parameters. Med Biol Eng. 1974 Jul; 12(4):415-24.
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  259. Vito L, Dennis RC, Weisel RD, Hechtman HB. Sepsis presenting as acute respiratory insufficiency. Surg Gynecol Obstet. 1974 Jun; 138(6):896-900.
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  260. Katz SJ, Lieberman A, Hechtman HB. Spontaneous perforation of the esophagus associated with smooth muscle hypertrophy. Am J Surg. 1974 Mar; 127(3):338-41.
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  261. Mackay RS, Hechtman HB. Continuous monitoring of cardiac output. Biotelemetry. 1974; 1(1):21-30.
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  262. Berger RL, Saini VK, Long W, Hechtman H, Hood W. The use of diastolic augmentation with the intra-aortic balloon in human septic shock with associated coronary artery disease. Surgery. 1973 Oct; 74(4):601-6.
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  263. Hechtman HB, Weisel RD, Vito L, Ali J, Berger RL. The independence of pulmonary shunting and pulmonary edema. Surgery. 1973 Aug; 74(2):300-6.
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  264. White MK, Shepro D, Hechtman HB. Pulmonary function and platelet-lung interaction. J Appl Physiol. 1973 May; 34(5):697-703.
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  265. Hechtman HB, Reid MH, Dorn BC, Weisel RD. Indicator dilution measurements of lung volumes and alveolar air exchange during breathing. J Clin Invest. 1973 May; 52(5):1215-29.
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  266. Fallon KD, Malenfant AL, Weisel RD, Hechtman HB. P50 determinations: techniques and clinical importance. Adv Exp Med Biol. 1973; 37A:93-7.
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  267. Berger RL, Rutenberg AM, Hechtman HB, Egdahl RH. The intensive-care laboratory. Surgery. 1973 Jan; 73(1):159-60.
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  268. Weisel RD, Vito L, Staunton HP, Hechtman HB. Treatment of acute respiratory insufficiency with cyclic expiratory pressure. Surg Forum. 1973; 24:234-6.
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  269. Hechtman HB, Reid MH, Dorn BC, Justice RE, Weisel RD. Shunting in the lung: a two-compartment model. Surgery. 1972 Sep; 72(3):443-50.
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  270. Kripke BJ, Hechtman HB. Nitrous oxide for pentazocine addiction and for intractable pain: report of case. Anesth Analg. 1972 Jul-Aug; 51(4):520-7.
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  271. Dorn BC, Justice RE, McCabe WR, Hechtman HB. A model for bacterial clearance in the lung. Surgery. 1972 Mar; 71(3):414-8.
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  272. Kien M, Hechtman H, Shepro D. Platelet-microvasculature interaction during one passage through the dog lung. Microvasc Res. 1971 Apr; 3(2):209-10.
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  273. Hechtman HB, Dorn BC, Herman AH. Lung volume and ventilation following shock. Surg Forum. 1971; 22:25-6.
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  274. Hechtman HB, Justice RE, Herman AH. A mercury injection system for rapid anaerobic collection of small blood samples. J Appl Physiol. 1970 Oct; 29(4):528-30.
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  275. Wangensteen SL, Hechtman HB, Rose LR, Vorder Bruegge CF. The Army in surgical research. J Surg Res. 1967 May; 7(5):239-45.
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  276. Collins JA, Hechtman HB, Theobald TJ, Blumenstock DA, Thomas ED, Ferrebee JW. Treatment by transfusion of severe general radiation injury in dogs. Transfusion. 1966 Mar-Apr; 6(2):134-9.
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  277. BLUMENSTOCK DA, COLLINS JA, HECHTMAN HB, HOSBEIN DJ, LEMPERT N, THOMAS ED, FERREBEE JW. LUNG TRANSPLANTATION IN THE DOG. Ann N Y Acad Sci. 1964 Nov 30; 120:677-88.
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  278. BLUMENSTOCK DA, COLLINS JA, HECHTMAN HB, HOSBEIN DJ, THOMAS ED, FERREBEE JW. LATE RESULTS OF HOMOTRANSPLANTATION OF THE LUNG IN DOGS. Dis Chest. 1964 May; 45:484-7.
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  279. HECHTMAN HB, BLUMENSTOCK DA, MITHOEFER J, POWERS JH. THE SURVIVAL OF RENAL HOMOTRANSPLANTS IN DOGS TREATED BY CHEMOTHERAPY, RADIATION, AND CROSS CIRCULATION. Ann Surg. 1964 Jan; 159:119-24.
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  280. BLUMENSTOCK DA, HECHTMAN HB, COLLINS JA, JARETZKI A, HOSBEIN JD, ZINGG W, POWERS JH. PROLONGED SURVIVAL OF ORTHOTOPIC HOMOTRANSPLANTS OF THE HEART IN ANIMALS TREATED WITH METHOTREXATE. J Thorac Cardiovasc Surg. 1963 Nov; 46:616-25.
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  281. BLUMENSTOCK DA, HECHTMAN HB, COLLINS JA. Preservation of the canine lung. J Thorac Cardiovasc Surg. 1962 Dec; 44:771-5.
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  282. BLUMENSTOCK DA, COLLINS JA, HECHTMAN HB, THOMAS ED, FERREBEE JW. Functioning homografts of the lung in dogs. Ann N Y Acad Sci. 1962 Oct 24; 99:882-90.
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