 Robert D. Lynch, D.Sc.
| Title | Lecturer on Pathology |
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| Institution | Massachusetts General Hospital |
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| Department | Pathology |
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| Address | Massachusetts General Hospital
Molecular Pathology Unit
149 13th Street
Charlestown MA 02129
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| Phone | 617/726-8495 |
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 Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Casas E, Barron C, Francis SA, McCormack JM, McCarthy KM, Schneeberger EE, Lynch RD. Cholesterol efflux stimulates metalloproteinase-mediated cleavage of occludin and release of extracellular membrane particles containing its C-terminal fragments. Exp Cell Res. 2010 Feb 1; 316(3):353-65.
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Kim J, Brienza DM, Lynch RD, Cooper RA, Boninger ML. Effectiveness evaluation of a remote accessibility assessment system for wheelchair users using virtualized reality. Arch Phys Med Rehabil. 2008 Mar; 89(3):470-9.
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Lynch RD, Francis SA, McCarthy KM, Casas E, Thiele C, Schneeberger EE. Cholesterol depletion alters detergent-specific solubility profiles of selected tight junction proteins and the phosphorylation of occludin. Exp Cell Res. 2007 Jul 15; 313(12):2597-610.
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Yu AS, McCarthy KM, Francis SA, McCormack JM, Lai J, Rogers RA, Lynch RD, Schneeberger EE. Knockdown of occludin expression leads to diverse phenotypic alterations in epithelial cells. Am J Physiol Cell Physiol. 2005 Jun; 288(6):C1231-41.
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Schneeberger EE, Lynch RD. The tight junction: a multifunctional complex. Am J Physiol Cell Physiol. 2004 Jun; 286(6):C1213-28.
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McCarthy KM, Francis SA, McCormack JM, Lai J, Rogers RA, Skare IB, Lynch RD, Schneeberger EE. Inducible expression of claudin-1-myc but not occludin-VSV-G results in aberrant tight junction strand formation in MDCK cells. J Cell Sci. 2000 Oct; 113 Pt 19:3387-98.
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Francis SA, Kelly JM, McCormack J, Rogers RA, Lai J, Schneeberger EE, Lynch RD. Rapid reduction of MDCK cell cholesterol by methyl-beta-cyclodextrin alters steady state transepithelial electrical resistance. Eur J Cell Biol. 1999 Jul; 78(7):473-84.
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McCarthy KM, Skare IB, Stankewich MC, Furuse M, Tsukita S, Rogers RA, Lynch RD, Schneeberger EE. Occludin is a functional component of the tight junction. J Cell Sci. 1996 Sep; 109 ( Pt 9):2287-98.
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Stankewich MC, Francis SA, Vu QU, Schneeberger EE, Lynch RD. Alterations in cell cholesterol content modulate Ca(2+)-induced tight junction assembly by MDCK cells. Lipids. 1996 Aug; 31(8):817-28.
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Lynch RD, Tkachuk-Ross LJ, McCormack JM, McCarthy KM, Rogers RA, Schneeberger EE. Basolateral but not apical application of protease results in a rapid rise of transepithelial electrical resistance and formation of aberrant tight junction strands in MDCK cells. Eur J Cell Biol. 1995 Mar; 66(3):257-67.
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Lynch RD, Tkachuk LJ, Ji X, Rabito CA, Schneeberger EE. Depleting cell cholesterol alters calcium-induced assembly of tight junctions by monolayers of MDCK cells. Eur J Cell Biol. 1993 Feb; 60(1):21-30.
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Schneeberger EE, Lynch RD. Structure, function, and regulation of cellular tight junctions. Am J Physiol. 1992 Jun; 262(6 Pt 1):L647-61.
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Ladino C, Schneeberger EE, Rabito CA, Lynch RD. Inhibition of adenine nucleotide synthesis: effect on tight junction structure and function of clone 4 MDCK cells. Eur J Cell Biol. 1991 Aug; 55(2):217-24.
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Schneeberger EE, Lynch RD, Neary BA. Interaction of native and chemically modified albumin with pulmonary microvascular endothelium. Am J Physiol. 1990 Feb; 258(2 Pt 1):L89-98.
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Ladino C, Schneeberger EE, Rabito CA, Lynch RD. Reduction of adenine nucleotide content of clone 4 MDCK cells: effects on multiplication, protein synthesis, and morphology. J Cell Physiol. 1989 Jul; 140(1):186-94.
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Schneeberger EE, Lynch RD, Kelly CA, Rabito CA. Modulation of tight junction formation in clone 4 MDCK cells by fatty acid supplementation. Am J Physiol. 1988 Mar; 254(3 Pt 1):C432-40.
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Lynch RD, Locicero J, Schneeberger EE. Metabolism and incorporation into glycerolipids of exogenous 18:3(n-3) and 18:3(n-6) by MDCK cells. Lipids. 1986 Jul; 21(7):447-53.
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Schneeberger EE, Lynch RD. Tight junctions. Their structure, composition, and function. Circ Res. 1984 Dec; 55(6):723-33.
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Lynch RD, Schneeberger EE, Geyer RP. Alterations in L fibroblast lipid metabolism and morphology during choline deprivation. Exp Cell Res. 1979 Aug; 122(1):103-13.
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Mulligan JJ, Lynch RD, Schneeberger EE, Geyer RP. Utilization of exogenous linolenic and oleic acids for plasma membrane phosphoglyceride synthesis in L-fibroblasts. Biochim Biophys Acta. 1977 Oct 3; 470(1):92-103.
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Schneeberger EE, Lynch RD, Geyer RP. Glutaraldehyde fixation used to demonstrate altered properties of outer mitochondrial membranes in polyunsaturated fatty acid (PUFA) supplemented cells. Exp Cell Res. 1976 Jun; 100(1):117-28.
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Lynch RD, Schneeberger EE, Geyer RP. Complete retention of phospholipid acyl groups by mammalian cells in culture. Biochemistry. 1976 Jan 13; 15(1):193-200.
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Schneeberger EE, Lynch RD, Geyer RP. Formation and disappearance of triglyceride droplets in strain L fibroblasts. An electron microscopic study. Exp Cell Res. 1971 Nov; 69(1):193-206.
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