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Lise Edelberg Nigrovic, M.D.

TitleAssistant Professor of Pediatrics
InstitutionChildren's Hospital Boston
DepartmentPediatrics
AddressChildrens Hospital
Emergency Medicine
300 Longwood Ave
Boston MA 02115
Phone617/355-6363
Fax617/730-0335

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Nigrovic LE, Fine AM, Monuteaux MC, Shah SS, Neuman MI. Trends in the Management of Viral Meningitis at United States Children's Hospitals. Pediatrics. 2013 Apr; 131(4):670-6.
    View in: PubMed
  2. Deanehan JK, Kimia AA, Tan Tanny SP, Milewski MD, Talusan PG, Smith BG, Nigrovic LE. Distinguishing lyme from septic knee monoarthritis in lyme disease-endemic areas. Pediatrics. 2013 Mar; 131(3):e695-701.
    View in: PubMed
  3. Mannix R, Fleegler E, Meehan WP, Schutzman SA, Hennelly K, Nigrovic L, Lee LK. Booster seat laws and fatalities in children 4 to 7 years of age. Pediatrics. 2012 Dec; 130(6):996-1002.
    View in: PubMed
  4. Nigrovic LE, Lillis K, Atabaki SM, Dayan PS, Hoyle J, Tunik MG, Jacobs ES, Monroe D, Wootton-Gorges SW, Miskin M, Holmes JF, Kuppermann N. The prevalence of traumatic brain injuries after minor blunt head trauma in children with ventricular shunts. Ann Emerg Med. 2013 Apr; 61(4):389-93.
    View in: PubMed
  5. Thompson AD, Cohn KA, Shah SS, Lyons T, Welsh EJ, Hines EM, Nigrovic LE. Treatment complications in children with lyme meningitis. Pediatr Infect Dis J. 2012 Oct; 31(10):1032-5.
    View in: PubMed
  6. Hennelly KE, Mannix R, Nigrovic LE, Lee LK, Thompson KM, Monuteaux MC, Proctor M, Schutzman S. Pediatric traumatic brain injury and radiation risks: a clinical decision analysis. J Pediatr. 2013 Feb; 162(2):392-7.
    View in: PubMed
  7. Nigrovic LE, Malley R, Kuppermann N. Meta-analysis of bacterial meningitis score validation studies. Arch Dis Child. 2012 Sep; 97(9):799-805.
    View in: PubMed
  8. Lyons TW, McAdam AJ, Cohn KA, Monuteaux MC, Nigrovic LE. Impact of in-hospital enteroviral polymerase chain reaction testing on the clinical management of children with meningitis. J Hosp Med. 2012 Sep; 7(7):517-20.
    View in: PubMed
  9. Nigrovic LE, Rogers AJ, Adelgais KM, Olsen CS, Leonard JR, Jaffe DM, Leonard JC. Utility of plain radiographs in detecting traumatic injuries of the cervical spine in children. Pediatr Emerg Care. 2012 May; 28(5):426-32.
    View in: PubMed
  10. Rogers EA, Kimia A, Madsen JR, Nigrovic LE, Neuman MI. Predictors of ventricular shunt infection among children presenting to a pediatric emergency department. Pediatr Emerg Care. 2012 May; 28(5):405-9.
    View in: PubMed
  11. Bargui F, D'Agostino I, Mariani-Kurkdjian P, Alberti C, Doit C, Bellier N, Morin L, Galli Gibertini G, Smail A, Zanin A, Lorrot M, Dauger S, Neve M, Faye A, Armoogum P, Bourrillon A, Bingen E, Mercier JC, Bonacorsi S, Nigrovic LE, Titomanlio L. Factors influencing neurological outcome of children with bacterial meningitis at the emergency department. Eur J Pediatr. 2012 Sep; 171(9):1365-71.
    View in: PubMed
  12. Kerrey BT, Rinderknecht AS, Geis GL, Nigrovic LE, Mittiga MR. Rapid sequence intubation for pediatric emergency patients: higher frequency of failed attempts and adverse effects found by video review. Ann Emerg Med. 2012 Sep; 60(3):251-9.
    View in: PubMed
  13. Hines EM, Nigrovic LE, Neuman MI, Shah SS. Adjustment of cerebrospinal fluid protein for red blood cells in neonates and young infants. J Hosp Med. 2012 Apr; 7(4):325-8.
    View in: PubMed
  14. Nigrovic LE, Kimia AA, Shah SS, Neuman MI. Relationship between cerebrospinal fluid glucose and serum glucose. N Engl J Med. 2012 Feb 9; 366(6):576-8.
    View in: PubMed
  15. Cohn KA, Thompson AD, Shah SS, Hines EM, Lyons TW, Welsh EJ, Nigrovic LE. Validation of a clinical prediction rule to distinguish Lyme meningitis from aseptic meningitis. Pediatrics. 2012 Jan; 129(1):e46-53.
    View in: PubMed
  16. Nigrovic LE, Lee LK, Hoyle J, Stanley RM, Gorelick MH, Miskin M, Atabaki SM, Dayan PS, Holmes JF, Kuppermann N. Prevalence of clinically important traumatic brain injuries in children with minor blunt head trauma and isolated severe injury mechanisms. Arch Pediatr Adolesc Med. 2012 Apr; 166(4):356-61.
    View in: PubMed
  17. Mannix R, Nigrovic LE, Schutzman SA, Hennelly K, Bourgeois FT, Meehan WP, Fleisher G, Monuteaux M, Lee LK. Factors associated with the use of cervical spine computed tomography imaging in pediatric trauma patients. Acad Emerg Med. 2011 Sep; 18(9):905-11.
    View in: PubMed
  18. Nigrovic LE, Schunk JE, Foerster A, Cooper A, Miskin M, Atabaki SM, Hoyle J, Dayan PS, Holmes JF, Kuppermann N. The effect of observation on cranial computed tomography utilization for children after blunt head trauma. Pediatrics. 2011 Jun; 127(6):1067-73.
    View in: PubMed
  19. Nigrovic LE, Shah SS, Neuman MI. Correction of cerebrospinal fluid protein for the presence of red blood cells in children with a traumatic lumbar puncture. J Pediatr. 2011 Jul; 159(1):158-9.
    View in: PubMed
  20. Fine AM, Brownstein JS, Nigrovic LE, Kimia AA, Olson KL, Thompson AD, Mandl KD. Integrating spatial epidemiology into a decision model for evaluation of facial palsy in children. Arch Pediatr Adolesc Med. 2011 Jan; 165(1):61-7.
    View in: PubMed
  21. Nigrovic LE, Malley R, Agrawal D, Kuppermann N. Low risk of bacterial meningitis in children with a positive enteroviral polymerase chain reaction test result. Clin Infect Dis. 2010 Nov 15; 51(10):1221-2.
    View in: PubMed
  22. Leonard JC, Kuppermann N, Olsen C, Babcock-Cimpello L, Brown K, Mahajan P, Adelgais KM, Anders J, Borgialli D, Donoghue A, Hoyle JD, Kim E, Leonard JR, Lillis KA, Nigrovic LE, Powell EC, Rebella G, Reeves SD, Rogers AJ, Stankovic C, Teshome G, Jaffe DM. Factors associated with cervical spine injury in children after blunt trauma. Ann Emerg Med. 2011 Aug; 58(2):145-55.
    View in: PubMed
  23. Cohn KA, Wingerter SL, Nigrovic LE. Tularemia. Encyclopedia of Intensive Care Medicine. Vincent JL, Hall J, eds. 2010.
  24. Fine AM, Reis BY, Nigrovic LE, Goldmann DA, Laporte TN, Olson KL, Mandl KD. Use of population health data to refine diagnostic decision-making for pertussis. J Am Med Inform Assoc. 2010 Jan-Feb; 17(1):85-90.
    View in: PubMed
  25. Ashley EA, Kimia A, Madsen JR, Nigrovic LE, Neuman MI. Predictors of Ventricular Shunt Infections in Children. American Academy of Pediatrics National Conference and Exhibition. 2009.
  26. Nigrovic LE. Aseptic meningitis. Handbook of Clinical Neurology - Pediatric Neurology. Dulac, Lassonde and Sarnat eds. 2009.
  27. Nigrovic LE, Rogers AJ, Adelgais K, OLson, C, Leonard J, Jaffe D, Leonard J. Utility of Plain Radiographs in Detecting Traumatic Injuries of the Cervical Spine in Children. American Academy of Pediatrics National Conference & Exhibition. 2009.
  28. Nigrovic LE, Dudley N, Nelson D. Neurologic emergencies. Essentials of Emergency Medicine. Aghababian RV, ed. 2009; (in press).
  29. Kanegaye JT, Nigrovic LE, Malley R, Cannavino CR, Schwab SH, Bennett JE, Mohseni MM, Wang VJ, Katsogridakis YL, Herman MI, Kuppermann N. Diagnostic value of immature neutrophils (bands) in the cerebrospinal fluid of children with cerebrospinal fluid pleocytosis. Pediatrics. 2009 Jun; 123(6):e967-71.
    View in: PubMed
  30. Nigrovic LE, Malley R, Macias CG, Kanegaye JT, Moro-Sutherland D, Bonsu BK, Agrawal D, Katsogridakis YL, Mansour KM, Steele DW, Schwab SH, Schremmer RD, Bennett JE, Mohseni MM, Kaplan RL, Herman MI, Bandyopadhyay S, Dayan P, Wang VJ, Kuppermann N. Enteroviral PCR testing for children with pretreated culture-negative meningitis. Pediatric Academic Society Meeting. 2009.
  31. Fine AM, Brownstein J, Nigrovic LE, Kimia A, Olson K, Thompson A, Mandl K. Integrating spatial epidemiology into a decision model for evaluation of a facial palsy in children. Pediatric Academic Society Meeting. 2009.
  32. Nigrovic LE, Malley R, Kuppermann N. Cerebrospinal fluid pleocytosis in children in the era of bacterial conjugate vaccines: distinguishing the child with bacterial and aseptic meningitis. Pediatr Emerg Care. 2009 Feb; 25(2):112-7; quiz 118-20.
    View in: PubMed
  33. Nigrovic LE, Neuman MI. Lumbar puncture. Procedures Consult (Emergency Medicine Module), Weiner DL, ed. 2009.
  34. Nigrovic LE, Thompson AD, Fine AM, Kimia A. Clinical predictors of Lyme disease among children with a peripheral facial palsy at an emergency department in a Lyme disease-endemic area. Pediatrics. 2008 Nov; 122(5):e1080-5.
    View in: PubMed
  35. Nigrovic LE, Malley R, Macias CG, Kanegaye JT, Moro-Sutherland DM, Schremmer RD, Schwab SH, Agrawal D, Mansour KM, Bennett JE, Katsogridakis YL, Mohseni MM, Bulloch B, Steele DW, Kaplan RL, Herman MI, Bandyopadhyay S, Dayan P, Truong UT, Wang VJ, Bonsu BK, Chapman JL, Kuppermann N. Effect of antibiotic pretreatment on cerebrospinal fluid profiles of children with bacterial meningitis. Pediatrics. 2008 Oct; 122(4):726-30.
    View in: PubMed
  36. Nigrovic LE, Wingerter SL. Tularemia. Infect Dis Clin North Am. 2008 Sep; 22(3):489-504, ix.
    View in: PubMed
  37. Nigrovic LE. Meningitis. Pocket Clinician: Pediatrics. 2008.
  38. Nigrovic LE. Aspirin Overdose. Pocket Clinician: Pediatrics. 2008.
  39. Nigrovic LE. Intussusception. Pocket Clinician: Pediatrics. 2008.
  40. Nigrovic LE. Sinusitis. Pocket Clinician: Pediatrics. 2008.
  41. Nigrovic LE, Kuppermann N, Malley R. Children with bacterial meningitis presenting to the emergency department during the pneumococcal conjugate vaccine era. Acad Emerg Med. 2008 Jun; 15(6):522-8.
    View in: PubMed
  42. Fine AM, Reis BY, Nigrovic LE, Goldmann DA, LaPorte TN, Olson KL, Mandl KD. Use of population health data to refine diagnostic decision making for pertussis. Pediatric Academic Society Meeting. 2008.
  43. Cannavino C., Nigrovic L., Malley R., Kanegaye J., Schwab S., Bennett J., Mohseni M., Wang V., Katsogridakis Y., Herman M., Kuppermann N. for the Pediatric Emergency Medicine Collaborative Research Committee of the AAP. The diagnostic value of immature neutrophils (“bands”) in the cerebrospinal fluid of children with cereobrospinal fluid pleocytosis. American Academy of Pediatrics National Conference and Exhibition. 2007.
  44. Nigrovic LE, Trivedi M, Edlow JA, Neuman MI. Cerebrospinal fluid xanthochromia in newborns is related to maternal labor before delivery. Pediatrics. 2007 Nov; 120(5):e1212-6.
    View in: PubMed
  45. Nigrovic LE, McQueen AA, Neuman MI. Lumbar puncture success rate is not influenced by family-member presence. Pediatrics. 2007 Oct; 120(4):e777-82.
    View in: PubMed
  46. Nigrovic LE, Burns MM. Heat Disorders. Comprehensive Pediatric Hospital Medicine. LB Zaoutis LB and Chiang VW, eds. 2007; 1(185):1148-1152.
  47. Nigrovic LE, Kuppermann N, Malley R. Letter in response. Clinical decision rule to identify patients at very low risk of bacterial meningitis. JAMA. 2007; 297(15):1653-1655.
  48. Nigrovic LE, Kuppermann N, Neuman MI. Risk factors for traumatic or unsuccessful lumbar punctures in children. Ann Emerg Med. 2007 Jun; 49(6):762-71.
    View in: PubMed
  49. Fine AM, Nigrovic LE, Reis BY, Cook EF, Mandl KD. Linking surveillance to action: incorporation of real-time regional data into a medical decision rule. J Am Med Inform Assoc. 2007 Mar-Apr; 14(2):206-11.
    View in: PubMed
  50. Nigrovic LE, Kuppermann N, Macias CG, Cannavino CR, Moro-Sutherland DM, Schremmer RD, Schwab SH, Agrawal D, Mansour KM, Bennett JE, Katsogridakis YL, Mohseni MM, Bulloch B, Steele DW, Kaplan RL, Herman MI, Bandyopadhyay S, Dayan P, Truong UT, Wang VJ, Bonsu BK, Chapman JL, Kanegaye JT, Malley R. Clinical prediction rule for identifying children with cerebrospinal fluid pleocytosis at very low risk of bacterial meningitis. JAMA. 2007 Jan 3; 297(1):52-60.
    View in: PubMed
  51. Stoll ML, Zurakowski D, Nigrovic LE, Nichols DP, Sundel RP, Nigrovic PA. Patients with juvenile psoriatic arthritis comprise two distinct populations. Arthritis Rheum. 2006 Nov; 54(11):3564-72.
    View in: PubMed
  52. Nigrovic LE, Thompson KM. The Lyme vaccine: a cautionary tale. Epidemiol Infect. 2007 Jan; 135(1):1-8.
    View in: PubMed
  53. Nigrovic LE, Nigrovic PA, Harper MB, Chiang VW. Extreme thrombocytosis predicts Kawasaki disease in infants. Clin Pediatr (Phila). 2006 Jun; 45(5):446-52.
    View in: PubMed
  54. Weiner D, Nigrovic LE, Manzi S, Shannon MW. Evaluation and management of pediatric disaster victims. Handbook of Bioterrorism and Disaster Medicine. Antosia RE and Cahill JD, eds. 2006; 369-374.
  55. Weiner D, Nigrovic LE, Manzi S, Shannon MW. Pediatric-specific disaster-related considerations. Handbook of Bioterrorism and Disaster Medicine. Antosia RE and Cahill JD, eds. 2006; 375-380.
  56. Weiner D, Nigrovic LE, Manzi S, Shannon MW. Pediatric specialty team response to disaster. Handbook of Bioterrorism and Disaster Medicine. Antosia RE and Cahill JD, eds. 2006; 381-385.
  57. Nigrovic LE, Kuppermann N, McAdam AJ, Malley R. Cerebrospinal latex agglutination fails to contribute to the microbiologic diagnosis of pretreated children with meningitis. Pediatr Infect Dis J. 2004 Aug; 23(8):786-8.
    View in: PubMed
  58. Nigrovic LE, Malley R. Evaluation of the febrile child 3 to 36 months old in the era of the pneumococcal conjugate vaccine: focus on occult bacteremia. Clin Pediatr Emerg Med. 2004; 49:13-19.
  59. Nigrovic LE, Kuppermann N, Malley R. Development and validation of a multivariable predictive model to distinguish bacterial from aseptic meningitis in children in the post-Haemophilus influenzae era. Pediatrics. 2002 Oct; 110(4):712-9.
    View in: PubMed
  60. Greenes D, Kim M, Nagler J, Nigrovic LE, Seigel B, Rehm K. Resident as Teacher: A Developmental Approach, presented at the American Pediatric Program Directors Meeting (Baltimore, MD). 2002.
  61. Nigrovic LE, Lumeng C, Landrigan C, Chiang VW. Rotavirus cerebellitis? Clin Infect Dis. 2002 Jan 1; 34(1):130.
    View in: PubMed
  62. Babl FE, Edelberg (Nigrovic) L, Shannon M. Airway sequelae after hair relaxer ingestion. Pediatr Emerg Care. 2001; 17(1):36-7.
  63. Rehm KP, Nigrovic LE. Introduction. Curr Opin Pediatr. 2001 Feb; 13(1):81.
    View in: PubMed
  64. Babl FE, Edelberg LH, Shannon M. Oral and airway sequelae after hair relaxer ingestion. Pediatr Emerg Care. 2001 Feb; 17(1):36-7.
    View in: PubMed
  65. Nigrovic LE. What's new with enteroviral infections? Curr Opin Pediatr. 2001 Feb; 13(1):89-94.
    View in: PubMed
  66. Nigrovic LE, Chiang VW. Cost analysis of enteroviral polymerase chain reaction in infants with fever and cerebrospinal fluid pleocytosis. Arch Pediatr Adolesc Med. 2000 Aug; 154(8):817-21.
    View in: PubMed
  67. Nigrovic LE. Pediatric Editor. Outlines in Clinical Medicine. 2000.
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