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Earl Francis Cook Jr., Sc.D.

TitleProfessor of Epidemiology
InstitutionHarvard School of Public Health
DepartmentEpidemiology
AddressHarvard School of Public Healt
Dept of Epidemiology
677 Huntington Ave
Boston MA 02115
Phone617/432-1050
Other Positions
TitleProfessor of Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
DivisionGeneral Medicine


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Grover S, Kastrinos F, Steyerberg EW, Cook EF, Dewanwala A, Burbidge LA, Wenstrup RJ, Syngal S. Prevalence and phenotypes of APC and MUTYH mutations in patients with multiple colorectal adenomas. JAMA. 2012 Aug 1; 308(5):485-92.
    View in: PubMed
  2. Juillerat P, Schneeweiss S, Cook EF, Ananthakrishnan AN, Mogun H, Korzenik JR. Drugs that inhibit gastric acid secretion may alter the course of inflammatory bowel disease. Aliment Pharmacol Ther. 2012 Aug; 36(3):239-47.
    View in: PubMed
  3. Baur DM, Christophi CA, Cook EF, Kales SN. Age-Related Decline in Cardiorespiratory Fitness among Career Firefighters: Modification by Physical Activity and Adiposity. J Obes. 2012; 2012:710903.
    View in: PubMed
  4. Sequist TD, Morong SM, Marston A, Keohane CA, Cook EF, Orav EJ, Lee TH. Electronic risk alerts to improve primary care management of chest pain: a randomized, controlled trial. J Gen Intern Med. 2012 Apr; 27(4):438-44.
    View in: PubMed
  5. Baur DM, Christophi CA, Tsismenakis AJ, Cook EF, Kales SN. Cardiorespiratory fitness predicts cardiovascular risk profiles in career firefighters. J Occup Environ Med. 2011 Oct; 53(10):1155-60.
    View in: PubMed
  6. Truong TH, Weeks JC, Cook EF, Joffe S. Altruism among participants in cancer clinical trials. Clin Trials. 2011 Oct; 8(5):616-23.
    View in: PubMed
  7. Mack JW, Wolfe J, Cook EF, Grier HE, Cleary PD, Weeks JC. Parents' roles in decision making for children with cancer in the first year of cancer treatment. J Clin Oncol. 2011 May 20; 29(15):2085-90.
    View in: PubMed
  8. Fox AA, Muehlschlegel JD, Body SC, Shernan SK, Liu KY, Perry TE, Aranki SF, Cook EF, Marcantonio ER, Collard CD. Comparison of the utility of preoperative versus postoperative B-type natriuretic peptide for predicting hospital length of stay and mortality after primary coronary artery bypass grafting. Anesthesiology. 2010 Apr; 112(4):842-51.
    View in: PubMed
  9. Garg P, Servoss SJ, Wu JC, Bajwa ZH, Selim MH, Dineen A, Kuntz RE, Cook EF, Mauri L. Lack of association between migraine headache and patent foramen ovale: results of a case-control study. Circulation. 2010 Mar 30; 121(12):1406-12.
    View in: PubMed
  10. Macadam SA, Ho AL, Cook EF, Lennox PA, Pusic AL. Patient satisfaction and health-related quality of life following breast reconstruction: patient-reported outcomes among saline and silicone implant recipients. Plast Reconstr Surg. 2010 Mar; 125(3):761-71.
    View in: PubMed
  11. Leffler DA, Dennis M, Edwards George J, Jamma S, Cook EF, Schuppan D, Kelly CP. A validated disease-specific symptom index for adults with celiac disease. Clin Gastroenterol Hepatol. 2009 Dec; 7(12):1328-34, 1334.e1-3.
    View in: PubMed
  12. Mack JW, Wolfe J, Cook EF, Grier HE, Cleary PD, Weeks JC. Peace of mind and sense of purpose as core existential issues among parents of children with cancer. Arch Pediatr Adolesc Med. 2009 Jun; 163(6):519-24.
    View in: PubMed
  13. Kastrinos F, Allen JI, Stockwell DH, Stoffel EM, Cook EF, Mutinga ML, Balmaña J, Syngal S. Development and validation of a colon cancer risk assessment tool for patients undergoing colonoscopy. Am J Gastroenterol. 2009 Jun; 104(6):1508-18.
    View in: PubMed
  14. Cheung WY, Neville BA, Cameron DB, Cook EF, Earle CC. Comparisons of patient and physician expectations for cancer survivorship care. J Clin Oncol. 2009 May 20; 27(15):2489-95.
    View in: PubMed
  15. Leffler DA, Dennis M, Edwards George JB, Jamma S, Magge S, Cook EF, Schuppan D, Kelly CP. A simple validated gluten-free diet adherence survey for adults with celiac disease. Clin Gastroenterol Hepatol. 2009 May; 7(5):530-6, 536.e1-2.
    View in: PubMed
  16. Lopez L, Cook EF, Horng MS, Hicks LS. Lifestyle modification counseling for hypertensive patients: results from the National Health and Nutrition Examination Survey 1999-2004. Am J Hypertens. 2009 Mar; 22(3):325-31.
    View in: PubMed
  17. Setoguchi S, Schneeweiss S, Brookhart MA, Glynn RJ, Cook EF. Evaluating uses of data mining techniques in propensity score estimation: a simulation study. Pharmacoepidemiol Drug Saf. 2008 Jun; 17(6):546-55.
    View in: PubMed
  18. Trichopoulos D, Cole P, Cook EF, Feinleib M, Hoover R, Hsieh CC, Hunter D, Monson R, Mueller N, Rahu M, Rimm E, Rothman K, Stampfer M, Weiss N, Willett W, Adami HO. Brian MacMahon (1923-2007): founder of modern epidemiology. Cancer Causes Control. 2008 May; 19(4):329-37.
    View in: PubMed
  19. Holt EW, Cook EF, Covar RA, Spahn J, Fuhlbrigge AL. Identifying the components of asthma health status in children with mild to moderate asthma. J Allergy Clin Immunol. 2008 May; 121(5):1175-80.
    View in: PubMed
  20. Edwards KE, Neville BA, Cook EF, Aldridge SH, Dussel V, Wolfe J. Understanding of prognosis and goals of care among couples whose child died of cancer. J Clin Oncol. 2008 Mar 10; 26(8):1310-5.
    View in: PubMed
  21. Treister NS, Cook EF, Antin J, Lee SJ, Soiffer R, Woo SB. Clinical evaluation of oral chronic graft-versus-host disease. Biol Blood Marrow Transplant. 2008 Jan; 14(1):110-5.
    View in: PubMed
  22. Mack JW, Wolfe J, Cook EF, Grier HE, Cleary PD, Weeks JC. Hope and prognostic disclosure. J Clin Oncol. 2007 Dec 10; 25(35):5636-42.
    View in: PubMed
  23. Leffler DA, Edwards George JB, Dennis M, Cook EF, Schuppan D, Kelly CP. A prospective comparative study of five measures of gluten-free diet adherence in adults with coeliac disease. Aliment Pharmacol Ther. 2007 Nov 1; 26(9):1227-35.
    View in: PubMed
  24. Bourgeois FT, Porter SC, Valim C, Jackson T, Cook EF, Mandl KD. The value of patient self-report for disease surveillance. J Am Med Inform Assoc. 2007 Nov-Dec; 14(6):765-71.
    View in: PubMed
  25. Setoguchi S, Solomon DH, Glynn RJ, Cook EF, Levin R, Schneeweiss S. Agreement of diagnosis and its date for hematologic malignancies and solid tumors between medicare claims and cancer registry data. Cancer Causes Control. 2007 Jun; 18(5):561-9.
    View in: PubMed
  26. Mack JW, Cook EF, Wolfe J, Grier HE, Cleary PD, Weeks JC. Understanding of prognosis among parents of children with cancer: parental optimism and the parent-physician interaction. J Clin Oncol. 2007 Apr 10; 25(11):1357-62.
    View in: PubMed
  27. Rothschild JM, McGurk S, Honour M, Lu L, McClendon AA, Srivastava P, Churchill WH, Kaufman RM, Avorn J, Cook EF, Bates DW. Assessment of education and computerized decision support interventions for improving transfusion practice. Transfusion. 2007 Feb; 47(2):228-39.
    View in: PubMed
  28. Fine AM, Nigrovic LE, Reis BY, Cook EF, Mandl KD. Linking surveillance to action: incorporation of real-time regional data into a medical decision rule. J Am Med Inform Assoc. 2007 Mar-Apr; 14(2):206-11.
    View in: PubMed
  29. Joffe S, Mello MM, Cook EF, Lee SJ. Advance care planning in patients undergoing hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2007 Jan; 13(1):65-73.
    View in: PubMed
  30. Scheurer DB, Hicks LS, Cook EF, Schnipper JL. Accuracy of ICD-9 coding for Clostridium difficile infections: a retrospective cohort. Epidemiol Infect. 2007 Aug; 135(6):1010-3.
    View in: PubMed
  31. Setoguchi S, Solomon DH, Weinblatt ME, Katz JN, Avorn J, Glynn RJ, Cook EF, Carney G, Schneeweiss S. Tumor necrosis factor alpha antagonist use and cancer in patients with rheumatoid arthritis. Arthritis Rheum. 2006 Sep; 54(9):2757-64.
    View in: PubMed
  32. Smith Fawzi MC, Lambert W, Singler J, Léandre F, Nevil P, Bertrand D, Claude MS, Bertrand J, Louissaint M, Jeannis L, Ferrer JG, Cook EF, Salazar JJ, Farmer P, Mukherjee JS. Identification of chlamydia and gonorrhoea among women in rural Haiti: maximising access to treatment in a resource poor setting. Sex Transm Infect. 2006 Apr; 82(2):175-81.
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  33. Schatz M, Mosen D, Apter AJ, Zeiger RS, Vollmer WM, Stibolt TB, Leong A, Johnson MS, Mendoza G, Cook EF. Relationships among quality of life, severity, and control measures in asthma: an evaluation using factor analysis. J Allergy Clin Immunol. 2005 May; 115(5):1049-55.
    View in: PubMed
  34. Sequist TD, Gandhi TK, Karson AS, Fiskio JM, Bugbee D, Sperling M, Cook EF, Orav EJ, Fairchild DG, Bates DW. A randomized trial of electronic clinical reminders to improve quality of care for diabetes and coronary artery disease. J Am Med Inform Assoc. 2005 Jul-Aug; 12(4):431-7.
    View in: PubMed
  35. Rothschild JM, Keohane CA, Cook EF, Orav EJ, Burdick E, Thompson S, Hayes J, Bates DW. A controlled trial of smart infusion pumps to improve medication safety in critically ill patients. Crit Care Med. 2005 Mar; 33(3):533-40.
    View in: PubMed
  36. Schatz M, Mosen D, Apter AJ, Zeiger RS, Vollmer WM, Stibolt TB, Leong A, Johnson MS, Mendoza G, Cook EF. Relationship of validated psychometric tools to subsequent medical utilization for asthma. J Allergy Clin Immunol. 2005 Mar; 115(3):564-70.
    View in: PubMed
  37. Sequist TD, Bates DW, Cook EF, Lampert S, Schaefer M, Wright J, Sato L, Lee TH. Prediction of missed myocardial infarction among symptomatic outpatients without coronary heart disease. Am Heart J. 2005 Jan; 149(1):74-81.
    View in: PubMed
  38. Morimoto T, Gandhi TK, Fiskio JM, Seger AC, So JW, Cook EF, Fukui T, Bates DW. An evaluation of risk factors for adverse drug events associated with angiotensin-converting enzyme inhibitors. J Eval Clin Pract. 2004 Nov; 10(4):499-509.
    View in: PubMed
  39. Morimoto T, Gandhi TK, Fiskio JM, Seger AC, So JW, Cook EF, Fukui T, Bates DW. Development and validation of a clinical prediction rule for angiotensin-converting enzyme inhibitor-induced cough. J Gen Intern Med. 2004 Jun; 19(6):684-91.
    View in: PubMed
  40. Peppercorn JM, Weeks JC, Cook EF, Joffe S. Comparison of outcomes in cancer patients treated within and outside clinical trials: conceptual framework and structured review. Lancet. 2004 Jan 24; 363(9405):263-70.
    View in: PubMed
  41. Schatz M, Cook EF, Joshua A, Petitti D. Risk factors for asthma hospitalizations in a managed care organization: development of a clinical prediction rule. Am J Manag Care. 2003 Aug; 9(8):538-47.
    View in: PubMed
  42. Schatz M, Cook EF, Nakahiro R, Petitti D. Inhaled corticosteroids and allergy specialty care reduce emergency hospital use for asthma. J Allergy Clin Immunol. 2003 Mar; 111(3):503-8.
    View in: PubMed
  43. Hicks LS, Fairchild DG, Cook EF, Ayanian JZ. Association of region of residence and immigrant status with hypertension, renal failure, cardiovascular disease, and stroke, among African-American participants in the third National Health and Nutrition Examination Survey (NHANES III). Ethn Dis. 2003; 13(3):316-23.
    View in: PubMed
  44. Sangha O, Schneeweiss S, Wildner M, Cook EF, Brennan TA, Witte J, Liang MH. Metric properties of the appropriateness evaluation protocol and predictors of inappropriate hospital use in Germany: an approach using longitudinal patient data. Int J Qual Health Care. 2002 Dec; 14(6):483-92.
    View in: PubMed
  45. Mahomed NN, Liang MH, Cook EF, Daltroy LH, Fortin PR, Fossel AH, Katz JN. The importance of patient expectations in predicting functional outcomes after total joint arthroplasty. J Rheumatol. 2002 Jun; 29(6):1273-9.
    View in: PubMed
  46. Wee CC, Phillips RS, Cook EF, Haas JS, Puopolo AL, Brennan TA, Burstin HR. Influence of body weight on patients' satisfaction with ambulatory care. J Gen Intern Med. 2002 Feb; 17(2):155-9.
    View in: PubMed
  47. Lee Sk, Cook EF, Soiffer R, Antin JH. Development and validation of a scale to measure symptoms of chronic graft-versus-host disease. Biol Blood Marrow Transplant. 2002; 8(8):444-52.
    View in: PubMed
  48. Joffe S, Cook EF, Cleary PD, Clark JW, Weeks JC. Quality of informed consent in cancer clinical trials: a cross-sectional survey. Lancet. 2001 Nov 24; 358(9295):1772-7.
    View in: PubMed
  49. Federman AD, Cook EF, Phillips RS, Puopolo AL, Haas JS, Brennan TA, Burstin HR. Intention to discontinue care among primary care patients: influence of physician behavior and process of care. J Gen Intern Med. 2001 Oct; 16(10):668-74.
    View in: PubMed
  50. Rohde LE, Polanczyk CA, Goldman L, Cook EF, Lee RT, Lee TH. Usefulness of transthoracic echocardiography as a tool for risk stratification of patients undergoing major noncardiac surgery. Am J Cardiol. 2001 Mar 1; 87(5):505-9.
    View in: PubMed
  51. Pearson SD, Kleefield SF, Soukop JR, Cook EF, Lee TH. Critical pathways intervention to reduce length of hospital stay. Am J Med. 2001 Feb 15; 110(3):175-80.
    View in: PubMed
  52. Wee CC, Phillips RS, Burstin HR, Cook EF, Puopolo AL, Brennan TA, Haas JS. Influence of financial productivity incentives on the use of preventive care. Am J Med. 2001 Feb 15; 110(3):181-7.
    View in: PubMed
  53. Joffe S, Cook EF, Cleary PD, Clark JW, Weeks JC. Quality of informed consent: a new measure of understanding among research subjects. J Natl Cancer Inst. 2001 Jan 17; 93(2):139-47.
    View in: PubMed
  54. Gandhi TK, Puopolo AL, Dasse P, Haas JS, Burstin HR, Cook EF, Brennan TA. Obstacles to collaborative quality improvement: the case of ambulatory general medical care. Int J Qual Health Care. 2000 Apr; 12(2):115-23.
    View in: PubMed
  55. Gandhi TK, Burstin HR, Cook EF, Puopolo AL, Haas JS, Brennan TA, Bates DW. Drug complications in outpatients. J Gen Intern Med. 2000 Mar; 15(3):149-54.
    View in: PubMed
  56. Hickey ML, Cook EF, Rossi LP, Connor J, Dutkiewicz C, Hassan SM, Fay M, Lee TH, Fairchild DG. Effect of case managers with a general medical patient population. J Eval Clin Pract. 2000 Feb; 6(1):23-9.
    View in: PubMed
  57. Simon SR, Shaneyfelt TM, Collins MM, Cook EF, Fletcher RH. Faculty training in general internal medicine: a survey of graduates from a research-intensive fellowship program. Acad Med. 1999 Nov; 74(11):1253-5.
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  58. Lee TH, Marcantonio ER, Mangione CM, Thomas EJ, Polanczyk CA, Cook EF, Sugarbaker DJ, Donaldson MC, Poss R, Ho KK, Ludwig LE, Pedan A, Goldman L. Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation. 1999 Sep 7; 100(10):1043-9.
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  59. Werneck GL, de Carvalho DM, Barroso DE, Cook EF, Walker AM. Classification trees and logistic regression applied to prognostic studies: a comparison using meningococcal disease as an example. J Trop Pediatr. 1999 Aug; 45(4):248-51.
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  60. Johnson PA, Goldman L, Sacks DB, Garcia T, Albano M, Bezai M, Pedan A, Cook EF, Lee TH. Cardiac troponin T as a marker for myocardial ischemia in patients seen at the emergency department for acute chest pain. Am Heart J. 1999 Jun; 137(6):1137-44.
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  61. Polanczyk CA, Johnson PA, Cook EF, Lee TH. A proposed strategy for utilization of creatine kinase-MB and troponin I in the evaluation of acute chest pain. Am J Cardiol. 1999 Apr 15; 83(8):1175-9.
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  62. Polanczyk CA, Lee TH, Cook EF, Walls R, Wybenga D, Johnson PA. Value of additional two-hour myoglobin for the diagnosis of myocardial infarction in the emergency department. Am J Cardiol. 1999 Feb 15; 83(4):525-9.
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  63. Lopez-Jimenez F, Goldman L, Johnson PA, Polanczyk CA, Cook EF, Fleischmann KE, Orav EJ, Lee TH. Effect of diabetes mellitus on the presentation and triage of patients with acute chest pain without known coronary artery disease. Am J Med. 1998 Dec; 105(6):500-5.
    View in: PubMed
  64. Marcantonio ER, Goldman L, Orav EJ, Cook EF, Lee TH. The association of intraoperative factors with the development of postoperative delirium. Am J Med. 1998 Nov; 105(5):380-4.
    View in: PubMed
  65. Bae SC, Cook EF, Kim SY. Psychometric evaluation of a Korean Health Assessment Questionnaire for clinical research. J Rheumatol. 1998 Oct; 25(10):1975-9.
    View in: PubMed
  66. Polanczyk CA, Lee TH, Cook EF, Walls R, Wybenga D, Printy-Klein G, Ludwig L, Guldbrandsen G, Johnson PA. Cardiac troponin I as a predictor of major cardiac events in emergency department patients with acute chest pain. J Am Coll Cardiol. 1998 Jul; 32(1):8-14.
    View in: PubMed
  67. Weeks JC, Cook EF, O'Day SJ, Peterson LM, Wenger N, Reding D, Harrell FE, Kussin P, Dawson NV, Connors AF, Lynn J, Phillips RS. Relationship between cancer patients' predictions of prognosis and their treatment preferences. JAMA. 1998 Jun 3; 279(21):1709-14.
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  68. Corley DA, Stefan AM, Wolf M, Cook EF, Lee TH. Early indicators of prognosis in upper gastrointestinal hemorrhage. Am J Gastroenterol. 1998 Mar; 93(3):336-40.
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  69. Tsevat J, Dawson NV, Wu AW, Lynn J, Soukup JR, Cook EF, Vidaillet H, Phillips RS. Health values of hospitalized patients 80 years or older. HELP Investigators. Hospitalized Elderly Longitudinal Project. JAMA. 1998 Feb 4; 279(5):371-5.
    View in: PubMed
  70. Fairchild DG, Hickey ML, Cook EF, McCarthy RM, Rossi LP, Timmons SC, Mangione CM, Lee TH. A prediction rule for the use of postdischarge medical services. J Gen Intern Med. 1998 Feb; 13(2):98-105.
    View in: PubMed
  71. Fleischmann KE, Lee RT, Come PC, Goldman L, Cook EF, Weissman MA, Johnson PA, Lee TH. Impact of valvular regurgitation and ventricular dysfunction on long-term survival in patients with chest pain. Am J Cardiol. 1997 Nov 15; 80(10):1266-72.
    View in: PubMed
  72. Lopez-Jimenez F, Goldman L, Sacks DB, Thomas EJ, Johnson PA, Cook EF, Lee TH. Prognostic value of cardiac troponin T after noncardiac surgery: 6-month follow-up data. J Am Coll Cardiol. 1997 May; 29(6):1241-5.
    View in: PubMed
  73. Wilson IB, Green ML, Goldman L, Tsevat J, Cook EF, Phillips RS. Is experience a good teacher? How interns and attending physicians understand patients' choices for end-of-life care. SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments. Med Decis Making. 1997 Apr-Jun; 17(2):217-27.
    View in: PubMed
  74. Thomas EJ, Goldman L, Mangione CM, Marcantonio ER, Cook EF, Ludwig L, Sugarbaker D, Poss R, Donaldson M, Lee TH. Body mass index as a correlate of postoperative complications and resource utilization. Am J Med. 1997 Mar; 102(3):277-83.
    View in: PubMed
  75. Chertow GM, Lazarus JM, Christiansen CL, Cook EF, Hammermeister KE, Grover F, Daley J. Preoperative renal risk stratification. Circulation. 1997 Feb 18; 95(4):878-84.
    View in: PubMed
  76. Fleischmann KE, Lee TH, Come PC, Goldman L, Cook EF, Caguoia E, Johnson PA, Albano MP, Lee RT. Echocardiographic prediction of complications in patients with chest pain. Am J Cardiol. 1997 Feb 1; 79(3):292-8.
    View in: PubMed
  77. Cornuz J, Pearson SD, Creager MA, Cook EF, Goldman L. Importance of findings on the initial evaluation for cancer in patients with symptomatic idiopathic deep venous thrombosis. Ann Intern Med. 1996 Nov 15; 125(10):785-93.
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  78. Haas JS, Berman S, Goldberg AB, Lee LW, Cook EF. Prenatal hospitalization and compliance with guidelines for prenatal care. Am J Public Health. 1996 Jun; 86(6):815-9.
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  79. Lee TH, Thomas EJ, Ludwig LE, Sacks DB, Johnson PA, Donaldson MC, Cook EF, Pedan A, Kuntz KM, Goldman L. Troponin T as a marker for myocardial ischemia in patients undergoing major noncardiac surgery. Am J Cardiol. 1996 May 15; 77(12):1031-6.
    View in: PubMed
  80. Matsui K, Goldman L, Johnson PA, Kuntz KM, Cook EF, Lee TH. Comorbidity as a correlate of length of stay for hospitalized patients with acute chest pain. J Gen Intern Med. 1996 May; 11(5):262-8.
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  81. Tsevat J, Cook EF, Green ML, Matchar DB, Dawson NV, Broste SK, Wu AW, Phillips RS, Oye RK, Goldman L. Health values of the seriously ill. SUPPORT investigators. Ann Intern Med. 1995 Apr 1; 122(7):514-20.
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  82. Lee TH, Pearson SD, Johnson PA, Garcia TB, Weisberg MC, Guadagnoli E, Cook EF, Goldman L. Failure of information as an intervention to modify clinical management. A time-series trial in patients with acute chest pain. Ann Intern Med. 1995 Mar 15; 122(6):434-7.
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  83. Feldman S, Cook EF, Harlow BL, Berkowitz RS. Predicting endometrial cancer among older women who present with abnormal vaginal bleeding. Gynecol Oncol. 1995 Mar; 56(3):376-81.
    View in: PubMed
  84. Covinsky KE, Goldman L, Cook EF, Oye R, Desbiens N, Reding D, Fulkerson W, Connors AF, Lynn J, Phillips RS. The impact of serious illness on patients' families. SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatment. JAMA. 1994 Dec 21; 272(23):1839-44.
    View in: PubMed
  85. Chin MH, Cook EF, Lee TH, Goldman L. Correlates of major complications and mortality in patients presenting to the emergency department with chest pain and more than bibasilar rales. J Gen Intern Med. 1994 Dec; 9(12):659-65.
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  86. Petersen LA, Brennan TA, O'Neil AC, Cook EF, Lee TH. Does housestaff discontinuity of care increase the risk for preventable adverse events? Ann Intern Med. 1994 Dec 1; 121(11):866-72.
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  87. Marcantonio ER, Juarez G, Goldman L, Mangione CM, Ludwig LE, Lind L, Katz N, Cook EF, Orav EJ, Lee TH. The relationship of postoperative delirium with psychoactive medications. JAMA. 1994 Nov 16; 272(19):1518-22.
    View in: PubMed
  88. Gaspoz JM, Lee TH, Weinstein MC, Cook EF, Goldman P, Komaroff AL, Goldman L. Cost-effectiveness of a new short-stay unit to "rule out" acute myocardial infarction in low risk patients. J Am Coll Cardiol. 1994 Nov 1; 24(5):1249-59.
    View in: PubMed
  89. Pearson SD, Goldman L, Garcia TB, Cook EF, Lee TH. Physician response to a prediction rule for the triage of emergency department patients with chest pain. J Gen Intern Med. 1994 May; 9(5):241-7.
    View in: PubMed
  90. Fleischmann KE, Goldman L, Robiolio PA, Lee RT, Johnson PA, Cook EF, Lee TH. Echocardiographic correlates of survival in patients with chest pain. J Am Coll Cardiol. 1994 May; 23(6):1390-6.
    View in: PubMed
  91. Pearson SD, Lee TH, Lindsey E, Hawkins T, Cook EF, Goldman L. The impact of membership in a health maintenance organization on hospital admission rates for acute chest pain. Health Serv Res. 1994 Apr; 29(1):59-74.
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  92. O'Neil AC, Petersen LA, Cook EF, Bates DW, Lee TH, Brennan TA. Physician reporting compared with medical-record review to identify adverse medical events. Ann Intern Med. 1993 Sep 1; 119(5):370-6.
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  93. Healey EA, Cook EF, Orav EJ, Schnitt SJ, Connolly JL, Harris JR. Contralateral breast cancer: clinical characteristics and impact on prognosis. J Clin Oncol. 1993 Aug; 11(8):1545-52.
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  94. Johnson PA, Lee TH, Cook EF, Rouan GW, Goldman L. Effect of race on the presentation and management of patients with acute chest pain. Ann Intern Med. 1993 Apr 15; 118(8):593-601.
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  95. Mangione CM, Marcantonio ER, Goldman L, Cook EF, Donaldson MC, Sugarbaker DJ, Poss R, Lee TH. Influence of age on measurement of health status in patients undergoing elective surgery. J Am Geriatr Soc. 1993 Apr; 41(4):377-83.
    View in: PubMed
  96. Raby KE, Barry J, Creager MA, Cook EF, Weisberg MC, Goldman L. Detection and significance of intraoperative and postoperative myocardial ischemia in peripheral vascular surgery. JAMA. 1992 Jul 8; 268(2):222-7.
    View in: PubMed
  97. Ting HH, Lee TH, Soukup JR, Cook EF, Tosteson AN, Brand DA, Rouan GW, Goldman L. Impact of physician experience on triage of emergency room patients with acute chest pain at three teaching hospitals. Am J Med. 1991 Oct; 91(4):401-8.
    View in: PubMed
  98. Gaspoz JM, Lee TH, Cook EF, Weisberg MC, Goldman L. Outcome of patients who were admitted to a new short-stay unit to "rule-out" myocardial infarction. Am J Cardiol. 1991 Jul 15; 68(2):145-9.
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  99. Braverman AC, Antin JH, Plappert MT, Cook EF, Lee RT. Cyclophosphamide cardiotoxicity in bone marrow transplantation: a prospective evaluation of new dosing regimens. J Clin Oncol. 1991 Jul; 9(7):1215-23.
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  100. Lee TH, Juarez G, Cook EF, Weisberg MC, Rouan GW, Brand DA, Goldman L. Ruling out acute myocardial infarction. A prospective multicenter validation of a 12-hour strategy for patients at low risk. N Engl J Med. 1991 May 2; 324(18):1239-46.
    View in: PubMed
  101. Raby KE, Goldman L, Cook EF, Rumerman J, Barry J, Creager MA, Selwyn AP. Long-term prognosis of myocardial ischemia detected by Holter monitoring in peripheral vascular disease. Am J Cardiol. 1990 Dec 1; 66(19):1309-13.
    View in: PubMed
  102. Goldman L, Cook EF, Orav J, Epstein AM, Komaroff AL, Delbanco TL, Mulley AG, Hiatt HH. Research training in clinical effectiveness: replacing "in my experience ..." with rigorous clinical investigation. Clin Res. 1990 Dec; 38(4):686-93.
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  103. Bates DW, Cook EF, Goldman L, Lee TH. Predicting bacteremia in hospitalized patients. A prospectively validated model. Ann Intern Med. 1990 Oct 1; 113(7):495-500.
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  104. Lee TH, Cook EF, Weisberg MC, Rouan GW, Brand DA, Goldman L. Impact of the availability of a prior electrocardiogram on the triage of the patient with acute chest pain. J Gen Intern Med. 1990 Sep-Oct; 5(5):381-8.
    View in: PubMed
  105. White LD, Lee TH, Cook EF, Weisberg MC, Rouan GW, Brand DA, Goldman L. Comparison of the natural history of new onset and exacerbated chronic ischemic heart disease. The Chest Pain Study Group. J Am Coll Cardiol. 1990 Aug; 16(2):304-10.
    View in: PubMed
  106. Lee TH, Cook EF, Fendrick AM, Shammash JB, Wolfe EP, Weisberg MC, Goldman L. Impact of initial triage decisions on nursing intensity for patients with acute chest pain. Med Care. 1990 Aug; 28(8):737-45.
    View in: PubMed
  107. Rouan GW, Lee TH, Cook EF, Brand DA, Weisberg MC, Goldman L. Clinical characteristics and outcome of acute myocardial infarction in patients with initially normal or nonspecific electrocardiograms (a report from the Multicenter Chest Pain Study). Am J Cardiol. 1989 Nov 15; 64(18):1087-92.
    View in: PubMed
  108. Raby KE, Goldman L, Creager MA, Cook EF, Weisberg MC, Whittemore AD, Selwyn AP. Correlation between preoperative ischemia and major cardiac events after peripheral vascular surgery. N Engl J Med. 1989 Nov 9; 321(19):1296-300.
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  109. Cunningham MA, Lee TH, Cook EF, Brand DA, Rouan GW, Weisberg MC, Goldman L. The effect of gender on the probability of myocardial infarction among emergency department patients with acute chest pain: a report from the Multicenter Chest Pain Study Group. J Gen Intern Med. 1989 Sep-Oct; 4(5):392-8.
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  110. Solomon CG, Lee TH, Cook EF, Weisberg MC, Brand DA, Rouan GW, Goldman L. Comparison of clinical presentation of acute myocardial infarction in patients older than 65 years of age to younger patients: the Multicenter Chest Pain Study experience. Am J Cardiol. 1989 Apr 1; 63(12):772-6.
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  111. Buchwald D, Komaroff AL, Cook EF, Epstein AM. Indirect costs for medical education. Is there a July phenomenon? Arch Intern Med. 1989 Apr; 149(4):765-8.
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  112. Clair WK, Chylack LT, Cook EF, Goldman L. Allopurinol use and the risk of cataract formation. Br J Ophthalmol. 1989 Mar; 73(3):173-6.
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  113. Grover SA, Cook EF, Adam J, Coupal L, Goldman L. Delayed diagnosis of gynecologic tumors in elderly women: relation to national medical practice patterns. Am J Med. 1989 Feb; 86(2):151-7.
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  114. Cook EF, Goldman L. Performance of tests of significance based on stratification by a multivariate confounder score or by a propensity score. J Clin Epidemiol. 1989; 42(4):317-24.
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  115. Goldman L, Sia ST, Cook EF, Rutherford JD, Weinstein MC. Costs and effectiveness of routine therapy with long-term beta-adrenergic antagonists after acute myocardial infarction. N Engl J Med. 1988 Jul 21; 319(3):152-7.
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  116. Hands ME, Cook EF, Stone PH, Muller JE, Hartwell T, Sobel BE, Roberts R, Braunwald E, Rutherford JD. Electrocardiographic diagnosis of myocardial infarction in the presence of complete left bundle branch block. Am Heart J. 1988 Jul; 116(1 Pt 1):23-31.
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  117. Lee RT, Cook EF, Day SC, Goldman L. Long-term survival after transient loss of consciousness. J Gen Intern Med. 1988 Jul-Aug; 3(4):337-43.
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  118. Goldman L, Cook EF, Brand DA, Lee TH, Rouan GW, Weisberg MC, Acampora D, Stasiulewicz C, Walshon J, Terranova G, et al. A computer protocol to predict myocardial infarction in emergency department patients with chest pain. N Engl J Med. 1988 Mar 31; 318(13):797-803.
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  119. Cook EF, Goldman L. Asymmetric stratification. An outline for an efficient method for controlling confounding in cohort studies. Am J Epidemiol. 1988 Mar; 127(3):626-39.
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  120. Grover SA, Cook EF, Goldman L. The impact of Medicare on early cancer detection in the elderly. Am J Public Health. 1988 Jan; 78(1):58-60.
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  121. Beamer AD, Lee TH, Cook EF, Brand DA, Rouan GW, Weisberg MC, Goldman L. Diagnostic implications for myocardial ischemia of the circadian variation of the onset of chest pain. Am J Cardiol. 1987 Nov 1; 60(13):998-1002.
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  122. Day SC, Cook EF, Funkenstein H, Goldman L. Evaluation and outcome of emergency room patients with transient loss of consciousness. Am J Med. 1982 Jul; 73(1):15-23.
    View in: PubMed
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