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Michael Barry Brenner, M.D.

TitleTheodore Bevier Bayles Professor of Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressBrigham and Women's Hospital
Smith Bldg, Rm 552
1 Jimmy Fund Way
Boston MA 02115
Phone617/525-1000
Fax617/525-1001

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Veerapen N, Leadbetter EA, Brenner MB, Cox LR, Besra GS. Synthesis of a novel alpha-galactosyl ceramide haptenated-lipid antigen, a useful tool in demonstrating the involvement of iNKT cells in the production of antilipid antibodies. Bioconjug Chem. 2010 Apr 21; 21(4):741-7.
    View in: PubMed
  2. Porcelli S, Brenner MB, Greenstein JL, Terhorst C, Balk SP, Bleicher PA. Recognition of Cluster of Differentiation 1 Antigens by Human CD4-CD8- CytolyticT Lymphocyte. Nature. 1989. 341: 447-450. 1989. J Immunol. 2010 Apr 1; 184(7):3306-9.
    View in: PubMed
  3. Kiener HP, Watts GF, Cui Y, Wright J, Thornhill TS, Sköld M, Behar SM, Niederreiter B, Lu J, Cernadas M, Coyle AJ, Sims GP, Smolen J, Warman ML, Brenner MB, Lee DM. Synovial fibroblasts self-direct multicellular lining architecture and synthetic function in three-dimensional organ culture. Arthritis Rheum. 2010 Mar; 62(3):742-52.
    View in: PubMed
  4. Odyniec AN, Barral DC, Garg S, Tatituri RV, Besra GS, Brenner MB. Regulation of CD1 antigen-presenting complex stability. J Biol Chem. 2010 Apr 16; 285(16):11937-47.
    View in: PubMed
  5. Muindi K, Cernadas M, Watts GF, Royle L, Neville DC, Dwek RA, Besra GS, Rudd PM, Butters TD, Brenner MB. Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d [corrected]. Proc Natl Acad Sci U S A. 2010 Feb 16; 107(7):3052-7.
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  6. Chang SK, Gu Z, Brenner MB. Fibroblast-like synoviocytes in inflammatory arthritis pathology: the emerging role of cadherin-11. Immunol Rev. 2010 Jan; 233(1):256-66.
    View in: PubMed
  7. Cernadas M, Cavallari M, Watts G, Mori L, De Libero G, Brenner MB. Early recycling compartment trafficking of CD1a is essential for its intersection and presentation of lipid antigens. J Immunol. 2010 Feb 1; 184(3):1235-41.
    View in: PubMed
  8. Brigl M, Brenner MB. How invariant natural killer T cells respond to infection by recognizing microbial or endogenous lipid antigens. Semin Immunol. 2010 Apr; 22(2):79-86.
    View in: PubMed
  9. Chiba A, Cohen N, Brigl M, Brennan PJ, Besra GS, Brenner MB. Rapid and reliable generation of invariant natural killer T-cell lines in vitro. Immunology. 2009 Nov; 128(3):324-33.
    View in: PubMed
  10. Felio K, Nguyen H, Dascher CC, Choi HJ, Li S, Zimmer MI, Colmone A, Moody DB, Brenner MB, Wang CR. CD1-restricted adaptive immune responses to Mycobacteria in human group 1 CD1 transgenic mice. J Exp Med. 2009 Oct 26; 206(11):2497-509.
    View in: PubMed
  11. Modlin RL, Brenner MB. T cell responses in microbial infection. Curr Opin Immunol. 2009 Aug; 21(4):365-6.
    View in: PubMed
  12. Veerapen N, Brigl M, Garg S, Cerundolo V, Cox LR, Brenner MB, Besra GS. Synthesis and biological activity of alpha-galactosyl ceramide KRN7000 and galactosyl (alpha1-->2) galactosyl ceramide. Bioorg Med Chem Lett. 2009 Aug 1; 19(15):4288-91.
    View in: PubMed
  13. Van Rhijn I, Young DC, De Jong A, Vazquez J, Cheng TY, Talekar R, Barral DC, Barral D, León L, Brenner MB, Katz JT, Riese R, Ruprecht RM, O'Connor PB, Costello CE, Porcelli SA, Briken V, Moody DB. CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids. J Exp Med. 2009 Jun 8; 206(6):1409-22.
    View in: PubMed
  14. Kiener HP, Niederreiter B, Lee DM, Jimenez-Boj E, Smolen JS, Brenner MB. Cadherin 11 promotes invasive behavior of fibroblast-like synoviocytes. Arthritis Rheum. 2009 May; 60(5):1305-10.
    View in: PubMed
  15. Cernadas M, Lu J, Watts G, Brenner MB. CD1a expression defines an interleukin-12 producing population of human dendritic cells. Clin Exp Immunol. 2009 Mar; 155(3):523-33.
    View in: PubMed
  16. Cohen NR, Garg S, Brenner MB. Antigen Presentation by CD1 Lipids, T Cells, and NKT Cells in Microbial Immunity. Adv Immunol. 2009; 102:1-94.
    View in: PubMed
  17. Sada-Ovalle I, Chiba A, Gonzales A, Brenner MB, Behar SM. Innate invariant NKT cells recognize Mycobacterium tuberculosis-infected macrophages, produce interferon-gamma, and kill intracellular bacteria. PLoS Pathog. 2008 Dec; 4(12):e1000239.
    View in: PubMed
  18. Brenner M, Coelho SG, Beer JZ, Miller SA, Wolber R, Smuda C, Hearing VJ. Long-lasting molecular changes in human skin after repetitive in situ UV irradiation. J Invest Dermatol. 2009 Apr; 129(4):1002-11.
    View in: PubMed
  19. Chiba A, Dascher CC, Besra GS, Brenner MB. Rapid NKT cell responses are self-terminating during the course of microbial infection. J Immunol. 2008 Aug 15; 181(4):2292-302.
    View in: PubMed
  20. Hava DL, van der Wel N, Cohen N, Dascher CC, Houben D, León L, Agarwal S, Sugita M, van Zon M, Kent SC, Shams H, Peters PJ, Brenner MB. Evasion of peptide, but not lipid antigen presentation, through pathogen-induced dendritic cell maturation. Proc Natl Acad Sci U S A. 2008 Aug 12; 105(32):11281-6.
    View in: PubMed
  21. Kaser A, Hava DL, Dougan SK, Chen Z, Zeissig S, Brenner MB, Blumberg RS. Microsomal triglyceride transfer protein regulates endogenous and exogenous antigen presentation by group 1 CD1 molecules. Eur J Immunol. 2008 Aug; 38(8):2351-9.
    View in: PubMed
  22. Barral DC, Cavallari M, McCormick PJ, Garg S, Magee AI, Bonifacino JS, De Libero G, Brenner MB. CD1a and MHC class I follow a similar endocytic recycling pathway. Traffic. 2008 Sep; 9(9):1446-57.
    View in: PubMed
  23. Leadbetter EA, Brigl M, Illarionov P, Cohen N, Luteran MC, Pillai S, Besra GS, Brenner MB. NK T cells provide lipid antigen-specific cognate help for B cells. Proc Natl Acad Sci U S A. 2008 Jun 17; 105(24):8339-44.
    View in: PubMed
  24. Noss EH, Brenner MB. The role and therapeutic implications of fibroblast-like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritis. Immunol Rev. 2008 Jun; 223:252-70.
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  25. Leslie DS, Dascher CC, Cembrola K, Townes MA, Hava DL, Hugendubler LC, Mueller E, Fox L, Roura-Mir C, Moody DB, Vincent MS, Gumperz JE, Illarionov PA, Besra GS, Reynolds CG, Brenner MB. Serum lipids regulate dendritic cell CD1 expression and function. Immunology. 2008 Nov; 125(3):289-301.
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  26. Agarwal SK, Lee DM, Kiener HP, Brenner MB. Coexpression of two mesenchymal cadherins, cadherin 11 and N-cadherin, on murine fibroblast-like synoviocytes. Arthritis Rheum. 2008 Apr; 58(4):1044-54.
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  27. Barral DC, Brenner MB. CD1 antigen presentation: how it works. Nat Rev Immunol. 2007 Dec; 7(12):929-41.
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  28. Parisini E, Higgins JM, Liu JH, Brenner MB, Wang JH. The crystal structure of human E-cadherin domains 1 and 2, and comparison with other cadherins in the context of adhesion mechanism. J Mol Biol. 2007 Oct 19; 373(2):401-11.
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  29. Lee DM, Kiener HP, Agarwal SK, Noss EH, Watts GF, Chisaka O, Takeichi M, Brenner MB. Cadherin-11 in synovial lining formation and pathology in arthritis. Science. 2007 Feb 16; 315(5814):1006-10.
    View in: PubMed
  30. Sugita M, Barral DC, Brenner MB. Pathways of CD1 and lipid antigen delivery, trafficking, processing, loading, and presentation. Curr Top Microbiol Immunol. 2007; 314:143-64.
    View in: PubMed
  31. Agarwal SK, Brenner MB. Role of adhesion molecules in synovial inflammation. Curr Opin Rheumatol. 2006 May; 18(3):268-76.
    View in: PubMed
  32. Kiener HP, Lee DM, Agarwal SK, Brenner MB. Cadherin-11 induces rheumatoid arthritis fibroblast-like synoviocytes to form lining layers in vitro. Am J Pathol. 2006 May; 168(5):1486-99.
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  33. Brigl M, van den Elzen P, Chen X, Meyers JH, Wu D, Wong CH, Reddington F, Illarianov PA, Besra GS, Brenner MB, Gumperz JE. Conserved and heterogeneous lipid antigen specificities of CD1d-restricted NKT cell receptors. J Immunol. 2006 Mar 15; 176(6):3625-34.
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  34. Kiener HP, Stipp CS, Allen PG, Higgins JM, Brenner MB. The cadherin-11 cytoplasmic juxtamembrane domain promotes alpha-catenin turnover at adherens junctions and intercellular motility. Mol Biol Cell. 2006 May; 17(5):2366-76.
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  35. Bry L, Brigl M, Brenner MB. CD4+-T-cell effector functions and costimulatory requirements essential for surviving mucosal infection with Citrobacter rodentium. Infect Immun. 2006 Jan; 74(1):673-81.
    View in: PubMed
  36. Vincent MS, Xiong X, Grant EP, Peng W, Brenner MB. CD1a-, b-, and c-restricted TCRs recognize both self and foreign antigens. J Immunol. 2005 Nov 15; 175(10):6344-51.
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  37. van den Elzen P, Garg S, León L, Brigl M, Leadbetter EA, Gumperz JE, Dascher CC, Cheng TY, Sacks FM, Illarionov PA, Besra GS, Kent SC, Moody DB, Brenner MB. Apolipoprotein-mediated pathways of lipid antigen presentation. Nature. 2005 Oct 6; 437(7060):906-10.
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  38. Miller MM, Wang C, Parisini E, Coletta RD, Goto RM, Lee SY, Barral DC, Townes M, Roura-Mir C, Ford HL, Brenner MB, Dascher CC. Characterization of two avian MHC-like genes reveals an ancient origin of the CD1 family. Proc Natl Acad Sci U S A. 2005 Jun 14; 102(24):8674-9.
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  39. van der Wel NN, Fluitsma DM, Dascher CC, Brenner MB, Peters PJ. Subcellular localization of mycobacteria in tissues and detection of lipid antigens in organelles using cryo-techniques for light and electron microscopy. Curr Opin Microbiol. 2005 Jun; 8(3):323-30.
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  40. Watts GM, Beurskens FJ, Martin-Padura I, Ballantyne CM, Klickstein LB, Brenner MB, Lee DM. Manifestations of inflammatory arthritis are critically dependent on LFA-1. J Immunol. 2005 Mar 15; 174(6):3668-75.
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  41. Hava DL, Brigl M, van den Elzen P, Zajonc DM, Wilson IA, Brenner MB. CD1 assembly and the formation of CD1-antigen complexes. Curr Opin Immunol. 2005 Feb; 17(1):88-94.
    View in: PubMed
  42. Zajonc DM, Crispin MD, Bowden TA, Young DC, Cheng TY, Hu J, Costello CE, Rudd PM, Dwek RA, Miller MJ, Brenner MB, Moody DB, Wilson IA. Molecular mechanism of lipopeptide presentation by CD1a. Immunity. 2005 Feb; 22(2):209-19.
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  43. Kiener HP, Brenner MB. Building the synovium: cadherin-11 mediates fibroblast-like synoviocyte cell-to-cell adhesion. Arthritis Res Ther. 2005; 7(2):49-54.
    View in: PubMed
  44. Valencia X, Higgins JM, Kiener HP, Lee DM, Podrebarac TA, Dascher CC, Watts GF, Mizoguchi E, Simmons B, Patel DD, Bhan AK, Brenner MB. Cadherin-11 provides specific cellular adhesion between fibroblast-like synoviocytes. J Exp Med. 2004 Dec 20; 200(12):1673-9.
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  45. Bach JF, Bendelac A, Brenner MB, Cantor H, De Libero G, Kronenberg M, Lanier LL, Raulet DH, Shlomchik MJ, von Herrath MG. The role of innate immunity in autoimmunity. J Exp Med. 2004 Dec 20; 200(12):1527-31.
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  46. Xiong X, Morita CT, Bukowski JF, Brenner MB, Dascher CC. Identification of guinea pig gammadelta T cells and characterization during pulmonary tuberculosis. Vet Immunol Immunopathol. 2004 Nov; 102(1-2):33-44.
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  47. Das H, Sugita M, Brenner MB. Mechanisms of Vdelta1 gammadelta T cell activation by microbial components. J Immunol. 2004 Jun 1; 172(11):6578-86.
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  48. Sugita M, Cernadas M, Brenner MB. New insights into pathways for CD1-mediated antigen presentation. Curr Opin Immunol. 2004 Feb; 16(1):90-5.
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  49. Moody DB, Young DC, Cheng TY, Rosat JP, Roura-Mir C, O'Connor PB, Zajonc DM, Walz A, Miller MJ, Levery SB, Wilson IA, Costello CE, Brenner MB. T cell activation by lipopeptide antigens. Science. 2004 Jan 23; 303(5657):527-31.
    View in: PubMed
  50. Brigl M, Brenner MB. CD1: antigen presentation and T cell function. Annu Rev Immunol. 2004; 22:817-90.
    View in: PubMed
  51. Bry L, Brenner MB. Critical role of T cell-dependent serum antibody, but not the gut-associated lymphoid tissue, for surviving acute mucosal infection with Citrobacter rodentium, an attaching and effacing pathogen. J Immunol. 2004 Jan 1; 172(1):433-41.
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  52. Brenner MB, Gromada J, Efanov AM, Bokvist K, Mest HJ. Restoration of first-phase insulin secretion by the imidazoline compound LY374284 in pancreatic islets of diabetic db/db mice. Ann N Y Acad Sci. 2003 Dec; 1009:332-40.
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  53. Brigl M, Bry L, Kent SC, Gumperz JE, Brenner MB. Mechanism of CD1d-restricted natural killer T cell activation during microbial infection. Nat Immunol. 2003 Dec; 4(12):1230-7.
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  54. Cernadas M, Sugita M, van der Wel N, Cao X, Gumperz JE, Maltsev S, Besra GS, Behar SM, Peters PJ, Brenner MB. Lysosomal localization of murine CD1d mediated by AP-3 is necessary for NK T cell development. J Immunol. 2003 Oct 15; 171(8):4149-55.
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  55. Rauch J, Gumperz J, Robinson C, Sköld M, Roy C, Young DC, Lafleur M, Moody DB, Brenner MB, Costello CE, Behar SM. Structural features of the acyl chain determine self-phospholipid antigen recognition by a CD1d-restricted invariant NKT (iNKT) cell. J Biol Chem. 2003 Nov 28; 278(48):47508-15.
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  56. Peña-Cruz V, Ito S, Dascher CC, Brenner MB, Sugita M. Epidermal Langerhans cells efficiently mediate CD1a-dependent presentation of microbial lipid antigens to T cells. J Invest Dermatol. 2003 Sep; 121(3):517-21.
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  57. Thomas SY, Hou R, Boyson JE, Means TK, Hess C, Olson DP, Strominger JL, Brenner MB, Gumperz JE, Wilson SB, Luster AD. CD1d-restricted NKT cells express a chemokine receptor profile indicative of Th1-type inflammatory homing cells. J Immunol. 2003 Sep 1; 171(5):2571-80.
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  58. Dascher CC, Brenner MB. Evolutionary constraints on CD1 structure: insights from comparative genomic analysis. Trends Immunol. 2003 Aug; 24(8):412-8.
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  59. Dascher CC, Hiromatsu K, Xiong X, Morehouse C, Watts G, Liu G, McMurray DN, LeClair KP, Porcelli SA, Brenner MB. Immunization with a mycobacterial lipid vaccine improves pulmonary pathology in the guinea pig model of tuberculosis. Int Immunol. 2003 Aug; 15(8):915-25.
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  60. Brandes M, Willimann K, Lang AB, Nam KH, Jin C, Brenner MB, Morita CT, Moser B. Flexible migration program regulates gamma delta T-cell involvement in humoral immunity. Blood. 2003 Nov 15; 102(10):3693-701.
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  61. van der Wel NN, Sugita M, Fluitsma DM, Cao X, Schreibelt G, Brenner MB, Peters PJ. CD1 and major histocompatibility complex II molecules follow a different course during dendritic cell maturation. Mol Biol Cell. 2003 Aug; 14(8):3378-88.
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  62. Vincent MS, Gumperz JE, Brenner MB. Understanding the function of CD1-restricted T cells. Nat Immunol. 2003 Jun; 4(6):517-23.
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  63. Kawashima T, Norose Y, Watanabe Y, Enomoto Y, Narazaki H, Watari E, Tanaka S, Takahashi H, Yano I, Brenner MB, Sugita M. Cutting edge: major CD8 T cell response to live bacillus Calmette-Guérin is mediated by CD1 molecules. J Immunol. 2003 Jun 1; 170(11):5345-8.
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  64. Dodge IL, Carr MW, Cernadas M, Brenner MB. IL-6 production by pulmonary dendritic cells impedes Th1 immune responses. J Immunol. 2003 May 1; 170(9):4457-64.
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  65. Araki M, Kondo T, Gumperz JE, Brenner MB, Miyake S, Yamamura T. Th2 bias of CD4+ NKT cells derived from multiple sclerosis in remission. Int Immunol. 2003 Feb; 15(2):279-88.
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  66. Barthel R, Tsytsykova AV, Barczak AK, Tsai EY, Dascher CC, Brenner MB, Goldfeld AE. Regulation of tumor necrosis factor alpha gene expression by mycobacteria involves the assembly of a unique enhanceosome dependent on the coactivator proteins CBP/p300. Mol Cell Biol. 2003 Jan; 23(2):526-33.
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  67. Dascher CC, Brenner MB. CD1 antigen presentation and infectious disease. Contrib Microbiol. 2003; 10:164-82.
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  68. Leslie DS, Vincent MS, Spada FM, Das H, Sugita M, Morita CT, Brenner MB. CD1-mediated gamma/delta T cell maturation of dendritic cells. J Exp Med. 2002 Dec 16; 196(12):1575-84.
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  69. Dascher CC, Hiromatsu K, Xiong X, Sugita M, Buhlmann JE, Dodge IL, Lee SY, Roura-Mir C, Watts GF, Roy CJ, Behar SM, Clemens DL, Porcelli SA, Brenner MB. Conservation of CD1 intracellular trafficking patterns between mammalian species. J Immunol. 2002 Dec 15; 169(12):6951-8.
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  70. Vincent MS, Leslie DS, Gumperz JE, Xiong X, Grant EP, Brenner MB. CD1-dependent dendritic cell instruction. Nat Immunol. 2002 Dec; 3(12):1163-8.
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  71. Cao X, Sugita M, Van Der Wel N, Lai J, Rogers RA, Peters PJ, Brenner MB. CD1 molecules efficiently present antigen in immature dendritic cells and traffic independently of MHC class II during dendritic cell maturation. J Immunol. 2002 Nov 1; 169(9):4770-7.
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  72. Lee DM, Friend DS, Gurish MF, Benoist C, Mathis D, Brenner MB. Mast cells: a cellular link between autoantibodies and inflammatory arthritis. Science. 2002 Sep 6; 297(5587):1689-92.
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  73. Hiromatsu K, Dascher CC, LeClair KP, Sugita M, Furlong ST, Brenner MB, Porcelli SA. Induction of CD1-restricted immune responses in guinea pigs by immunization with mycobacterial lipid antigens. J Immunol. 2002 Jul 1; 169(1):330-9.
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  74. Hiromatsu K, Dascher CC, Sugita M, Gingrich-Baker C, Behar SM, LeClair KP, Brenner MB, Porcelli SA. Characterization of guinea-pig group 1 CD1 proteins. Immunology. 2002 Jun; 106(2):159-72.
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  75. Sugita M, Cao X, Watts GF, Rogers RA, Bonifacino JS, Brenner MB. Failure of trafficking and antigen presentation by CD1 in AP-3-deficient cells. Immunity. 2002 May; 16(5):697-706.
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  76. Grant EP, Beckman EM, Behar SM, Degano M, Frederique D, Besra GS, Wilson IA, Porcelli SA, Furlong ST, Brenner MB. Fine specificity of TCR complementarity-determining region residues and lipid antigen hydrophilic moieties in the recognition of a CD1-lipid complex. J Immunol. 2002 Apr 15; 168(8):3933-40.
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  77. Shen Y, Zhou D, Qiu L, Lai X, Simon M, Shen L, Kou Z, Wang Q, Jiang L, Estep J, Hunt R, Clagett M, Sehgal PK, Li Y, Zeng X, Morita CT, Brenner MB, Letvin NL, Chen ZW. Adaptive immune response of Vgamma2Vdelta2+ T cells during mycobacterial infections. Science. 2002 Mar 22; 295(5563):2255-8.
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  78. Gumperz JE, Miyake S, Yamamura T, Brenner MB. Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining. J Exp Med. 2002 Mar 4; 195(5):625-36.
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  79. Giuliani A, Prete SP, Graziani G, Aquino A, Balduzzi A, Sugita M, Brenner MB, Iona E, Fattorini L, Orefici G, Porcelli SA, Bonmassar E. Influence of Mycobacterium bovis bacillus Calmette Guérin on in vitro induction of CD1 molecules in human adherent mononuclear cells. Infect Immun. 2001 Dec; 69(12):7461-70.
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  80. Gumperz JE, Brenner MB. CD1-specific T cells in microbial immunity. Curr Opin Immunol. 2001 Aug; 13(4):471-8.
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  81. Sugita M, Brenner MB. T lymphocyte recognition of human group 1 CD1 molecules: implications for innate and acquired immunity. Semin Immunol. 2000 Dec; 12(6):511-6.
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  82. Bukowski JF, Roncarolo MG, Spits H, Krangel MS, Morita CT, Brenner MB, Band H. T cell receptor-dependent activation of human lymphocytes through cell surface ganglioside GT1b: implications for innate immunity. Eur J Immunol. 2000 Nov; 30(11):3199-206.
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  83. Melián A, Watts GF, Shamshiev A, De Libero G, Clatworthy A, Vincent M, Brenner MB, Behar S, Niazi K, Modlin RL, Almo S, Ostrov D, Nathenson SG, Porcelli SA. Molecular recognition of human CD1b antigen complexes: evidence for a common pattern of interaction with alpha beta TCRs. J Immunol. 2000 Oct 15; 165(8):4494-504.
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  84. Moody DB, Guy MR, Grant E, Cheng TY, Brenner MB, Besra GS, Porcelli SA. CD1b-mediated T cell recognition of a glycolipid antigen generated from mycobacterial lipid and host carbohydrate during infection. J Exp Med. 2000 Oct 2; 192(7):965-76.
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  85. Agace WW, Higgins JM, Sadasivan B, Brenner MB, Parker CM. T-lymphocyte-epithelial-cell interactions: integrin alpha(E)(CD103)beta(7), LEEP-CAM and chemokines. Curr Opin Cell Biol. 2000 Oct; 12(5):563-8.
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  86. Higgins JM, Cernadas M, Tan K, Irie A, Wang J, Takada Y, Brenner MB. The role of alpha and beta chains in ligand recognition by beta 7 integrins. J Biol Chem. 2000 Aug 18; 275(33):25652-64.
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  87. Sugita M, van Der Wel N, Rogers RA, Peters PJ, Brenner MB. CD1c molecules broadly survey the endocytic system. Proc Natl Acad Sci U S A. 2000 Jul 18; 97(15):8445-50.
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  88. Sieling PA, Ochoa MT, Jullien D, Leslie DS, Sabet S, Rosat JP, Burdick AE, Rea TH, Brenner MB, Porcelli SA, Modlin RL. Evidence for human CD4+ T cells in the CD1-restricted repertoire: derivation of mycobacteria-reactive T cells from leprosy lesions. J Immunol. 2000 May 1; 164(9):4790-6.
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  89. Taraszka KS, Higgins JM, Tan K, Mandelbrot DA, Wang JH, Brenner MB. Molecular basis for leukocyte integrin alpha(E)beta(7) adhesion to epithelial (E)-cadherin. J Exp Med. 2000 May 1; 191(9):1555-67.
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  90. Moody DB, Ulrichs T, Mühlecker W, Young DC, Gurcha SS, Grant E, Rosat JP, Brenner MB, Costello CE, Besra GS, Porcelli SA. CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection. Nature. 2000 Apr 20; 404(6780):884-8.
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  91. Sugita M, Peters PJ, Brenner MB. Pathways for lipid antigen presentation by CD1 molecules: nowhere for intracellular pathogens to hide. Traffic. 2000 Apr; 1(4):295-300.
    View in: PubMed
  92. Spada FM, Grant EP, Peters PJ, Sugita M, Melián A, Leslie DS, Lee HK, van Donselaar E, Hanson DA, Krensky AM, Majdic O, Porcelli SA, Morita CT, Brenner MB. Self-recognition of CD1 by gamma/delta T cells: implications for innate immunity. J Exp Med. 2000 Mar 20; 191(6):937-48.
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  93. Gumperz JE, Roy C, Makowska A, Lum D, Sugita M, Podrebarac T, Koezuka Y, Porcelli SA, Cardell S, Brenner MB, Behar SM. Murine CD1d-restricted T cell recognition of cellular lipids. Immunity. 2000 Feb; 12(2):211-21.
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  94. Morita CT, Mariuzza RA, Brenner MB. Antigen recognition by human gamma delta T cells: pattern recognition by the adaptive immune system. Springer Semin Immunopathol. 2000; 22(3):191-217.
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  95. Li Z, Kim SH, Higgins JM, Brenner MB, Sacks DB. IQGAP1 and calmodulin modulate E-cadherin function. J Biol Chem. 1999 Dec 31; 274(53):37885-92.
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  96. Sugita M, Grant EP, van Donselaar E, Hsu VW, Rogers RA, Peters PJ, Brenner MB. Separate pathways for antigen presentation by CD1 molecules. Immunity. 1999 Dec; 11(6):743-52.
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  97. Dascher CC, Hiromatsu K, Naylor JW, Brauer PP, Brown KA, Storey JR, Behar SM, Kawasaki ES, Porcelli SA, Brenner MB, LeClair KP. Conservation of a CD1 multigene family in the guinea pig. J Immunol. 1999 Nov 15; 163(10):5478-88.
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  98. Shieh CC, Sadasivan BK, Russell GJ, Schön MP, Parker CM, Brenner MB. Lymphocyte adhesion to epithelia and endothelia mediated by the lymphocyte endothelial-epithelial cell adhesion molecule glycoprotein. J Immunol. 1999 Aug 1; 163(3):1592-601.
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  99. Bukowski JF, Morita CT, Brenner MB. Human gamma delta T cells recognize alkylamines derived from microbes, edible plants, and tea: implications for innate immunity. Immunity. 1999 Jul; 11(1):57-65.
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  100. Behar SM, Dascher CC, Grusby MJ, Wang CR, Brenner MB. Susceptibility of mice deficient in CD1D or TAP1 to infection with Mycobacterium tuberculosis. J Exp Med. 1999 Jun 21; 189(12):1973-80.
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  101. Schön MP, Arya A, Murphy EA, Adams CM, Strauch UG, Agace WW, Marsal J, Donohue JP, Her H, Beier DR, Olson S, Lefrancois L, Brenner MB, Grusby MJ, Parker CM. Mucosal T lymphocyte numbers are selectively reduced in integrin alpha E (CD103)-deficient mice. J Immunol. 1999 Jun 1; 162(11):6641-9.
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  102. Chen YH, Wang B, Chun T, Zhao L, Cardell S, Behar SM, Brenner MB, Wang CR. Expression of CD1d2 on thymocytes is not sufficient for the development of NK T cells in CD1d1-deficient mice. J Immunol. 1999 Apr 15; 162(8):4560-6.
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  103. Grant EP, Degano M, Rosat JP, Stenger S, Modlin RL, Wilson IA, Porcelli SA, Brenner MB. Molecular recognition of lipid antigens by T cell receptors. J Exp Med. 1999 Jan 4; 189(1):195-205.
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  104. Rosat JP, Grant EP, Beckman EM, Dascher CC, Sieling PA, Frederique D, Modlin RL, Porcelli SA, Furlong ST, Brenner MB. CD1-restricted microbial lipid antigen-specific recognition found in the CD8+ alpha beta T cell pool. J Immunol. 1999 Jan 1; 162(1):366-71.
    View in: PubMed
  105. Behar SM, Podrebarac TA, Roy CJ, Wang CR, Brenner MB. Diverse TCRs recognize murine CD1. J Immunol. 1999 Jan 1; 162(1):161-7.
    View in: PubMed
  106. Ho SC, Rajagopalan S, Chaudhuri S, Shieh CC, Brenner MB, Pillai S. Membrane anchoring of calnexin facilitates its interaction with its targets. Mol Immunol. 1999 Jan; 36(1):1-12.
    View in: PubMed
  107. Shaw SK, Hermanowski-Vosatka A, Shibahara T, McCormick BA, Parkos CA, Carlson SL, Ebert EC, Brenner MB, Madara JL. Migration of intestinal intraepithelial lymphocytes into a polarized epithelial monolayer. Am J Physiol. 1998 Sep; 275(3 Pt 1):G584-91.
    View in: PubMed
  108. Porcelli SA, Segelke BW, Sugita M, Wilson IA, Brenner MB. The CD1 family of lipid antigen-presenting molecules. Immunol Today. 1998 Aug; 19(8):362-8.
    View in: PubMed
  109. Bukowski JF, Morita CT, Band H, Brenner MB. Crucial role of TCR gamma chain junctional region in prenyl pyrophosphate antigen recognition by gamma delta T cells. J Immunol. 1998 Jul 1; 161(1):286-93.
    View in: PubMed
  110. Sugita M, Moody DB, Jackman RM, Grant EP, Rosat JP, Behar SM, Peters PJ, Porcelli SA, Brenner MB. CD1--a new paradigm for antigen presentation and T cell activation. Clin Immunol Immunopathol. 1998 Apr; 87(1):8-14.
    View in: PubMed
  111. Tentori L, Graziani G, Porcelli SA, Sugita M, Brenner MB, Madaio R, Bonmassar E, Giuliani A, Aquino A. Rifampin increases cytokine-induced expression of the CD1b molecule in human peripheral blood monocytes. Antimicrob Agents Chemother. 1998 Mar; 42(3):550-4.
    View in: PubMed
  112. Behar SM, Roy C, Lederer J, Fraser P, Brenner MB. Clonally expanded Valpha12+ (AV12S1),CD8+ T cells from a patient with rheumatoid arthritis are autoreactive. Arthritis Rheum. 1998 Mar; 41(3):498-506.
    View in: PubMed
  113. Li H, Lebedeva MI, Llera AS, Fields BA, Brenner MB, Mariuzza RA. Structure of the Vdelta domain of a human gammadelta T-cell antigen receptor. Nature. 1998 Jan 29; 391(6666):502-6.
    View in: PubMed
  114. Higgins JM, Mandlebrot DA, Shaw SK, Russell GJ, Murphy EA, Chen YT, Nelson WJ, Parker CM, Brenner MB. Direct and regulated interaction of integrin alphaEbeta7 with E-cadherin. J Cell Biol. 1998 Jan 12; 140(1):197-210.
    View in: PubMed
  115. Giuliani A, Porcelli SA, Tentori L, Graziani G, Testorelli C, Prete SP, Bussini S, Cappelletti D, Brenner MB, Bonmassar E, Aquino A. Effect of rifampin on CD1b expression and double-negative T cell responses against mycobacteria-derived glycolipid antigen. Life Sci. 1998; 63(12):985-94.
    View in: PubMed
  116. Mazzaccaro RJ, Stenger S, Rock KL, Porcelli SA, Brenner MB, Modlin RL, Bloom BR. Cytotoxic T lymphocytes in resistance to tuberculosis. Adv Exp Med Biol. 1998; 452:85-101.
    View in: PubMed
  117. Roth SJ, Diacovo TG, Brenner MB, Rosat JP, Buccola J, Morita CT, Springer TA. Transendothelial chemotaxis of human alpha/beta and gamma/delta T lymphocytes to chemokines. Eur J Immunol. 1998 Jan; 28(1):104-13.
    View in: PubMed
  118. Sugita M, Porcelli SA, Brenner MB. Assembly and retention of CD1b heavy chains in the endoplasmic reticulum. J Immunol. 1997 Sep 1; 159(5):2358-65.
    View in: PubMed
  119. Porcelli SA, Brenner MB. Antigen presentation: mixing oil and water. Curr Biol. 1997 Aug 1; 7(8):R508-11.
    View in: PubMed
  120. Stenger S, Mazzaccaro RJ, Uyemura K, Cho S, Barnes PF, Rosat JP, Sette A, Brenner MB, Porcelli SA, Bloom BR, Modlin RL. Differential effects of cytolytic T cell subsets on intracellular infection. Science. 1997 Jun 13; 276(5319):1684-7.
    View in: PubMed
  121. Prigozy TI, Sieling PA, Clemens D, Stewart PL, Behar SM, Porcelli SA, Brenner MB, Modlin RL, Kronenberg M. The mannose receptor delivers lipoglycan antigens to endosomes for presentation to T cells by CD1b molecules. Immunity. 1997 Feb; 6(2):187-97.
    View in: PubMed
  122. Giuliani A, Tentori L, Pepponi R, Porcelli SA, Aquino A, Orlando L, Sugita M, Brenner MB, Bonmassar E, Graziani G. Cytokine-induced expression of CD1b molecules by peripheral blood monocytes: influence of 3'-azido-3'-deoxythymidine. Pharmacol Res. 1997 Feb; 35(2):135-40.
    View in: PubMed
  123. Lebedeva MI, Fields BA, Spits H, Panchamoorthy G, Brenner MB, Mariuzza RA. Cloning, expression, and crystallization of the V delta domain of a human gamma delta T-cell receptor. Protein Sci. 1996 Dec; 5(12):2638-42.
    View in: PubMed
  124. Russell GJ, Parker CM, Sood A, Mizoguchi E, Ebert EC, Bhan AK, Brenner MB. p126 (CDw101), a costimulatory molecule preferentially expressed on mucosal T lymphocytes. J Immunol. 1996 Oct 15; 157(8):3366-74.
    View in: PubMed
  125. Moody DB, Sugita M, Peters PJ, Brenner MB, Porcelli SA. The CD1-restricted T-cell response to mycobacteria. Res Immunol. 1996 Oct-Dec; 147(8-9):550-9.
    View in: PubMed
  126. Sugita M, Jackman RM, van Donselaar E, Behar SM, Rogers RA, Peters PJ, Brenner MB, Porcelli SA. Cytoplasmic tail-dependent localization of CD1b antigen-presenting molecules to MIICs. Science. 1996 Jul 19; 273(5273):349-52.
    View in: PubMed
  127. Cepek KL, Rimm DL, Brenner MB. Expression of a candidate cadherin in T lymphocytes. Proc Natl Acad Sci U S A. 1996 Jun 25; 93(13):6567-71.
    View in: PubMed
  128. Morita CT, Tanaka Y, Bloom BR, Brenner MB. Direct presentation of non-peptide prenyl pyrophosphate antigens to human gamma delta T cells. Res Immunol. 1996 Jun; 147(5):347-53.
    View in: PubMed
  129. Tanaka Y, Brenner MB, Bloom BR, Morita CT. Recognition of nonpeptide antigens by T cells. J Mol Med (Berl). 1996 May; 74(5):223-31.
    View in: PubMed
  130. Diacovo TG, Roth SJ, Morita CT, Rosat JP, Brenner MB, Springer TA. Interactions of human alpha/beta and gamma/delta T lymphocyte subsets in shear flow with E-selectin and P-selectin. J Exp Med. 1996 Mar 1; 183(3):1193-203.
    View in: PubMed
  131. Melián A, Beckman EM, Porcelli SA, Brenner MB. Antigen presentation by CD1 and MHC-encoded class I-like molecules. Curr Opin Immunol. 1996 Feb; 8(1):82-8.
    View in: PubMed
  132. Behar SM, Porcelli SA, Beckman EM, Brenner MB. A pathway of costimulation that prevents anergy in CD28- T cells: B7-independent costimulation of CD1-restricted T cells. J Exp Med. 1995 Dec 1; 182(6):2007-18.
    View in: PubMed
  133. Morita CT, Beckman EM, Bukowski JF, Tanaka Y, Band H, Bloom BR, Golan DE, Brenner MB. Direct presentation of nonpeptide prenyl pyrophosphate antigens to human gamma delta T cells. Immunity. 1995 Oct; 3(4):495-507.
    View in: PubMed
  134. Shaw SK, Brenner MB. The beta 7 integrins in mucosal homing and retention. Semin Immunol. 1995 Oct; 7(5):335-42.
    View in: PubMed
  135. Sieling PA, Chatterjee D, Porcelli SA, Prigozy TI, Mazzaccaro RJ, Soriano T, Bloom BR, Brenner MB, Kronenberg M, Brennan PJ, et al. CD1-restricted T cell recognition of microbial lipoglycan antigens. Science. 1995 Jul 14; 269(5221):227-30.
    View in: PubMed
  136. Travaglio-Encinozal A, Dersimonian H, Jorgensen C, Romagné F, Sany J, D'Angeac AD, Brenner MB, Rème T. T-cell receptor V beta gene usage in rheumatoid synovial follicles. Ann N Y Acad Sci. 1995 Jul 7; 756:201-3.
    View in: PubMed
  137. Behar SM, Roy C, Brenner MB. Expansions of V alpha 12 CD8+ T-cells in rheumatoid arthritis. Ann N Y Acad Sci. 1995 Jul 7; 756:130-7.
    View in: PubMed
  138. Beckman EM, Brenner MB. MHC class I-like, class II-like and CD1 molecules: distinct roles in immunity. Immunol Today. 1995 Jul; 16(7):349-52.
    View in: PubMed
  139. Tanaka Y, Morita CT, Tanaka Y, Nieves E, Brenner MB, Bloom BR. Natural and synthetic non-peptide antigens recognized by human gamma delta T cells. Nature. 1995 May 11; 375(6527):155-8.
    View in: PubMed
  140. Travaglio-Encinoza A, Chaouni I, Dersimonian H, Jorgensen C, Simony-Lafontaine J, Romagné F, Sany J, Dupuy d'Angeac AD, Brenner MB, Rème T. T cell receptor distribution in rheumatoid synovial follicles. J Rheumatol. 1995 Mar; 22(3):394-9.
    View in: PubMed
  141. Bukowski JF, Morita CT, Tanaka Y, Bloom BR, Brenner MB, Band H. V gamma 2V delta 2 TCR-dependent recognition of non-peptide antigens and Daudi cells analyzed by TCR gene transfer. J Immunol. 1995 Feb 1; 154(3):998-1006.
    View in: PubMed
  142. Sugita M, Brenner MB. Association of the invariant chain with major histocompatibility complex class I molecules directs trafficking to endocytic compartments. J Biol Chem. 1995 Jan 20; 270(3):1443-8.
    View in: PubMed
  143. Beckman EM, Porcelli SA, Morita CT, Behar SM, Furlong ST, Brenner MB. Recognition of a lipid antigen by CD1-restricted alpha beta+ T cells. Nature. 1994 Dec 15; 372(6507):691-4.
    View in: PubMed
  144. Sugita M, Brenner MB. An unstable beta 2-microglobulin: major histocompatibility complex class I heavy chain intermediate dissociates from calnexin and then is stabilized by binding peptide. J Exp Med. 1994 Dec 1; 180(6):2163-71.
    View in: PubMed
  145. Bukowski JF, Morita CT, Brenner MB. Recognition and destruction of virus-infected cells by human gamma delta CTL. J Immunol. 1994 Dec 1; 153(11):5133-40.
    View in: PubMed
  146. Cepek KL, Shaw SK, Parker CM, Russell GJ, Morrow JS, Rimm DL, Brenner MB. Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the alpha E beta 7 integrin. Nature. 1994 Nov 10; 372(6502):190-3.
    View in: PubMed
  147. Morita CT, Parker CM, Brenner MB, Band H. TCR usage and functional capabilities of human gamma delta T cells at birth. J Immunol. 1994 Nov 1; 153(9):3979-88.
    View in: PubMed
  148. Russell GJ, Parker CM, Cepek KL, Mandelbrot DA, Sood A, Mizoguchi E, Ebert EC, Brenner MB, Bhan AK. Distinct structural and functional epitopes of the alpha E beta 7 integrin. Eur J Immunol. 1994 Nov; 24(11):2832-41.
    View in: PubMed
  149. Tanaka Y, Sano S, Nieves E, De Libero G, Rosa D, Modlin RL, Brenner MB, Bloom BR, Morita CT. Nonpeptide ligands for human gamma delta T cells. Proc Natl Acad Sci U S A. 1994 Aug 16; 91(17):8175-9.
    View in: PubMed
  150. Smith TJ, Ducharme LA, Shaw SK, Parker CM, Brenner MB, Kilshaw PJ, Weis JH. Murine M290 integrin expression modulated by mast cell activation. Immunity. 1994 Aug; 1(5):393-403.
    View in: PubMed
  151. Kaoutzani P, Colgan SP, Cepek KL, Burkard PG, Carlson S, Delp-Archer C, Brenner MB, Madara JL. Reconstitution of cultured intestinal epithelial monolayers with a mucosal-derived T lymphocyte cell line. Modulation of epithelial phenotype dependent on lymphocyte-basolateral membrane apposition. J Clin Invest. 1994 Aug; 94(2):788-96.
    View in: PubMed
  152. Rajagopalan S, Brenner MB. Calnexin retains unassembled major histocompatibility complex class I free heavy chains in the endoplasmic reticulum. J Exp Med. 1994 Jul 1; 180(1):407-12.
    View in: PubMed
  153. Bergeron JJ, Brenner MB, Thomas DY, Williams DB. Calnexin: a membrane-bound chaperone of the endoplasmic reticulum. Trends Biochem Sci. 1994 Mar; 19(3):124-8.
    View in: PubMed
  154. Russell GJ, Parker CM, Cepek KL, Brenner MB, Bhan AK. Evidence for a structural difference in the CD7 polypeptide on human thymocytes and intraepithelial lymphocytes defined by a new monoclonal antibody, 3D9. Cell Immunol. 1994 Mar; 154(1):153-65.
    View in: PubMed
  155. Shaw SK, Cepek KL, Murphy EA, Russell GJ, Brenner MB, Parker CM. Molecular cloning of the human mucosal lymphocyte integrin alpha E subunit. Unusual structure and restricted RNA distribution. J Biol Chem. 1994 Feb 25; 269(8):6016-25.
    View in: PubMed
  156. Rajagopalan S, Xu Y, Brenner MB. Retention of unassembled components of integral membrane proteins by calnexin. Science. 1994 Jan 21; 263(5145):387-90.
    View in: PubMed
  157. Schreiber KL, Bell MP, Huntoon CJ, Rajagopalan S, Brenner MB, McKean DJ. Class II histocompatibility molecules associate with calnexin during assembly in the endoplasmic reticulum. Int Immunol. 1994 Jan; 6(1):101-11.
    View in: PubMed
  158. Porcelli S, Yockey CE, Brenner MB, Balk SP. Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- alpha/beta T cells demonstrates preferential use of several V beta genes and an invariant TCR alpha chain. J Exp Med. 1993 Jul 1; 178(1):1-16.
    View in: PubMed
  159. DerSimonian H, Sugita M, Glass DN, Maier AL, Weinblatt ME, Rème T, Brenner MB. Clonal V alpha 12.1+ T cell expansions in the peripheral blood of rheumatoid arthritis patients. J Exp Med. 1993 Jun 1; 177(6):1623-31.
    View in: PubMed
  160. David V, Hochstenbach F, Rajagopalan S, Brenner MB. Interaction with newly synthesized and retained proteins in the endoplasmic reticulum suggests a chaperone function for human integral membrane protein IP90 (calnexin). J Biol Chem. 1993 May 5; 268(13):9585-92.
    View in: PubMed
  161. Cepek KL, Parker CM, Madara JL, Brenner MB. Integrin alpha E beta 7 mediates adhesion of T lymphocytes to epithelial cells. J Immunol. 1993 Apr 15; 150(8 Pt 1):3459-70.
    View in: PubMed
  162. Parker CM, Pujades C, Brenner MB, Hemler ME. Alpha 4/180, a novel form of the integrin alpha 4 subunit. J Biol Chem. 1993 Apr 5; 268(10):7028-35.
    View in: PubMed
  163. Porcelli S, Morita CT, Brenner MB. CD1b restricts the response of human CD4-8- T lymphocytes to a microbial antigen. Nature. 1992 Dec 10; 360(6404):593-7.
    View in: PubMed
  164. Hochstenbach F, David V, Watkins S, Brenner MB. Endoplasmic reticulum resident protein of 90 kilodaltons associates with the T- and B-cell antigen receptors and major histocompatibility complex antigens during their assembly. Proc Natl Acad Sci U S A. 1992 May 15; 89(10):4734-8.
    View in: PubMed
  165. Parker CM, Cepek KL, Russell GJ, Shaw SK, Posnett DN, Schwarting R, Brenner MB. A family of beta 7 integrins on human mucosal lymphocytes. Proc Natl Acad Sci U S A. 1992 Mar 1; 89(5):1924-8.
    View in: PubMed
  166. Van Kerckhove C, Russell GJ, Deusch K, Reich K, Bhan AK, DerSimonian H, Brenner MB. Oligoclonality of human intestinal intraepithelial T cells. J Exp Med. 1992 Jan 1; 175(1):57-63.
    View in: PubMed
  167. Morita CT, Verma S, Aparicio P, Martinez C, Spits H, Brenner MB. Functionally distinct subsets of human gamma/delta T cells. Eur J Immunol. 1991 Dec; 21(12):2999-3007.
    View in: PubMed
  168. Panchamoorthy G, McLean J, Modlin RL, Morita CT, Ishikawa S, Brenner MB, Band H. A predominance of the T cell receptor V gamma 2/V delta 2 subset in human mycobacteria-responsive T cells suggests germline gene encoded recognition. J Immunol. 1991 Nov 15; 147(10):3360-9.
    View in: PubMed
  169. DerSimonian H, Band H, Brenner MB. "Increased frequency of T cell receptor V alpha 12.1 expression on CD8+ T cells: evidence that V alpha participates in shaping the peripheral T cell repertoire". J Exp Med. 1991 Nov 1; 174(5):1287.
    View in: PubMed
  170. Denning SM, Jones DM, Ware RE, Weinhold KJ, Brenner MB, Haynes BF. Analysis of clones derived from human CD7+CD4-CD8-CD3- thymocytes. Int Immunol. 1991 Oct; 3(10):1015-24.
    View in: PubMed
  171. DerSimonian H, Band H, Brenner MB. Increased frequency of T cell receptor V alpha 12.1 expression on CD8+ T cells: evidence that V alpha participates in shaping the peripheral T cell repertoire. J Exp Med. 1991 Sep 1; 174(3):639-48.
    View in: PubMed
  172. Janson CH, Grunewald J, Osterborg A, DerSimonian H, Brenner MB, Mellstedt H, Wigzell H. Predominant T cell receptor V gene usage in patients with abnormal clones of B cells. Blood. 1991 Apr 15; 77(8):1776-80.
    View in: PubMed
  173. Porcelli S, Brenner MB, Band H. Biology of the human gamma delta T-cell receptor. Immunol Rev. 1991 Apr; 120:137-83.
    View in: PubMed
  174. Uyemura K, Band H, Ohmen J, Brenner MB, Rea TH, Modlin RL. Gamma delta T cells in leprosy lesions. Curr Top Microbiol Immunol. 1991; 173:203-7.
    View in: PubMed
  175. Band H, Porcelli SA, Panchamoorthy G, McLean J, Morita CT, Ishikawa S, Modlin RL, Brenner MB. Antigens and antigen-presenting molecules for gamma delta T cells. Curr Top Microbiol Immunol. 1991; 173:229-34.
    View in: PubMed
  176. Band H, Panchamoorthy G, Mclean J, Morita CT, Ishikawa S, Modlin R, Brenner MB. Recognition of mycobacterial antigens by gamma delta T cells. Res Immunol. 1990 Sep; 141(7):645-51.
    View in: PubMed
  177. Parker CM, Groh V, Band H, Porcelli SA, Morita C, Fabbi M, Glass D, Strominger JL, Brenner MB. Evidence for extrathymic changes in the T cell receptor gamma/delta repertoire. J Exp Med. 1990 May 1; 171(5):1597-612.
    View in: PubMed
  178. Solomon KR, Krangel MS, McLean J, Brenner MB, Band H. Human T cell receptor-gamma and -delta chain pairing analyzed by transfection of a T cell receptor-delta negative mutant cell line. J Immunol. 1990 Feb 1; 144(3):1120-6.
    View in: PubMed
  179. Hochstenbach F, Brenner MB. Newly identified gamma delta and beta delta T-cell receptors. J Clin Immunol. 1990 Jan; 10(1):1-18.
    View in: PubMed
  180. Porcelli S, Brenner MB, Greenstein JL, Balk SP, Terhorst C, Bleicher PA. Recognition of cluster of differentiation 1 antigens by human CD4-CD8-cytolytic T lymphocytes. Nature. 1989 Oct 5; 341(6241):447-50.
    View in: PubMed
  181. Bank I, Hemler M, Brenner MB, Cohen D, Levy V, Belko J, Crouse C, Chess L. A novel monoclonal antibody, 1B3.1, binds to a new epitope of the VLA-1 molecule. Cell Immunol. 1989 Sep; 122(2):416-23.
    View in: PubMed
  182. Hochstenbach F, Brenner MB. T-cell receptor delta-chain can substitute for alpha to form a beta delta heterodimer. Nature. 1989 Aug 17; 340(6234):562-5.
    View in: PubMed
  183. Modlin RL, Pirmez C, Hofman FM, Torigian V, Uyemura K, Rea TH, Bloom BR, Brenner MB. Lymphocytes bearing antigen-specific gamma delta T-cell receptors accumulate in human infectious disease lesions. Nature. 1989 Jun 15; 339(6225):544-8.
    View in: PubMed
  184. Band H, Hochstenbach F, Parker CM, McLean J, Krangel MS, Brenner MB. Expression of human T cell receptor-gamma delta structural forms. J Immunol. 1989 May 15; 142(10):3627-33.
    View in: PubMed
  185. Groh V, Porcelli S, Fabbi M, Lanier LL, Picker LJ, Anderson T, Warnke RA, Bhan AK, Strominger JL, Brenner MB. Human lymphocytes bearing T cell receptor gamma/delta are phenotypically diverse and evenly distributed throughout the lymphoid system. J Exp Med. 1989 Apr 1; 169(4):1277-94.
    View in: PubMed
  186. Brenner MB, Hochstenbach F, Band H, Parker C, McLean J, Hata S, Krangel M. Human T cell receptor gamma delta structure. Adv Exp Med Biol. 1989; 254:17-9.
    View in: PubMed
  187. Minowada J, Kohno K, Matsuo Y, Drexler HG, Ohnuma T, Tax WJ, Brenner MB. Characteristics of 27 human T-cell leukemia cell lines with/without T-cell receptors of T3-Ti alpha beta or T3-Ti gamma delta complex. Haematol Blood Transfus. 1989; 32:233-6.
    View in: PubMed
  188. Picker LJ, Brenner MB, Michie S, Warnke RA. Expression of T cell receptor delta chains in benign and malignant T lineage lymphoproliferations. Am J Pathol. 1988 Sep; 132(3):401-5.
    View in: PubMed
  189. Brennan FM, Londei M, Jackson AM, Hercend T, Brenner MB, Maini RN, Feldmann M. T cells expressing gamma delta chain receptors in rheumatoid arthritis. J Autoimmun. 1988 Aug; 1(4):319-26.
    View in: PubMed
  190. Hata S, Satyanarayana K, Devlin P, Band H, McLean J, Strominger JL, Brenner MB, Krangel MS. Extensive junctional diversity of rearranged human T cell receptor delta genes. Science. 1988 Jun 10; 240(4858):1541-4.
    View in: PubMed
  191. Brenner MB, Strominger JL, Krangel MS. The gamma delta T cell receptor. Adv Immunol. 1988; 43:133-92.
    View in: PubMed
  192. Picker LJ, Brenner MB, Weiss LM, Smith SD, Warnke RA. Discordant expression of CD3 and T-cell receptor beta-chain antigens in T-lineage lymphomas. Am J Pathol. 1987 Dec; 129(3):434-40.
    View in: PubMed
  193. Band H, Hochstenbach F, McLean J, Hata S, Krangel MS, Brenner MB. Immunochemical proof that a novel rearranging gene encodes the T cell receptor delta subunit. Science. 1987 Oct 30; 238(4827):682-4.
    View in: PubMed
  194. Hata S, Brenner MB, Krangel MS. Identification of putative human T cell receptor delta complementary DNA clones. Science. 1987 Oct 30; 238(4827):678-82.
    View in: PubMed
  195. Modlin RL, Brenner MB, Krangel MS, Duby AD, Bloom BR. T-cell receptors of human suppressor cells. Nature. 1987 Oct 8-14; 329(6139):541-5.
    View in: PubMed
  196. Krangel MS, Band H, Hata S, McLean J, Brenner MB. Structurally divergent human T cell receptor gamma proteins encoded by distinct C gamma genes. Science. 1987 Jul 3; 237(4810):64-7.
    View in: PubMed
  197. Krangel MS, Bierer BE, Devlin P, Clabby M, Strominger JL, McLean J, Brenner MB. T3 glycoprotein is functional although structurally distinct on human T-cell receptor gamma T lymphocytes. Proc Natl Acad Sci U S A. 1987 Jun; 84(11):3817-21.
    View in: PubMed
  198. Maecker HT, Kitamura K, Brenner MB, Levy R. Isolation of anti-idiotypic antibodies to T cells using an anti-framework determinant antibody. J Immunol Methods. 1987 Apr 16; 98(2):219-26.
    View in: PubMed
  199. Brenner MB, McLean J, Scheft H, Warnke RA, Jones N, Strominger JL. Characterization and expression of the human alpha beta T cell receptor by using a framework monoclonal antibody. J Immunol. 1987 Mar 1; 138(5):1502-9.
    View in: PubMed
  200. Brenner MB, McLean J, Scheft H, Riberdy J, Ang SL, Seidman JG, Devlin P, Krangel MS. Two forms of the T-cell receptor gamma protein found on peripheral blood cytotoxic T lymphocytes. Nature. 1987 Feb 19-25; 325(6106):689-94.
    View in: PubMed
  201. Brenner MB, McLean J, Dialynas DP, Strominger JL, Smith JA, Owen FL, Seidman JG, Ip S, Rosen F, Krangel MS. Identification of a putative second T-cell receptor. Nature. 1986 Jul 10-16; 322(6075):145-9.
    View in: PubMed
  202. Bank I, DePinho RA, Brenner MB, Cassimeris J, Alt FW, Chess L. A functional T3 molecule associated with a novel heterodimer on the surface of immature human thymocytes. Nature. 1986 Jul 10-16; 322(6075):179-81.
    View in: PubMed
  203. Brenner MB, McLean J, Yang SY, van der Poel JJ, Pious D, Strominger JL. Clonal T lymphocyte recognition of the fine structure of the HLA-A2 molecule. J Immunol. 1985 Jul; 135(1):384-90.
    View in: PubMed
  204. Hemler ME, Jacobson JG, Brenner MB, Mann D, Strominger JL. VLA-1: a T cell surface antigen which defines a novel late stage of human T cell activation. Eur J Immunol. 1985 May; 15(5):502-8.
    View in: PubMed
  205. Brenner MB, Trowbridge IS, Strominger JL. Cross-linking of human T cell receptor proteins: association between the T cell idiotype beta subunit and the T3 glycoprotein heavy subunit. Cell. 1985 Jan; 40(1):183-90.
    View in: PubMed
  206. Maeda K, Kono D, Kobayashi S, Brenner MB, Yu DT. A study of the specificity of the direct binding between bacteria and HLA antigens. Clin Exp Immunol. 1984 Sep; 57(3):694-702.
    View in: PubMed
  207. Brenner MB, Trowbridge IS, McLean J, Strominger JL. Identification of shared antigenic determinants of the putative human T lymphocyte antigen receptor. J Exp Med. 1984 Aug 1; 160(2):541-51.
    View in: PubMed
  208. Hemler ME, Brenner MB, McLean JM, Strominger JL. Antigenic stimulation regulates the level of expression of interleukin 2 receptor on human T cells. Proc Natl Acad Sci U S A. 1984 Apr; 81(7):2172-5.
    View in: PubMed
  209. Brenner MB, Kobayashi S, Wiesenhutter CW, Huberman AK, Bales P, Yu DT. In vitro T lymphocyte proliferative response to Yersinia enterocolitica in Reiter's syndrome. Lack of response in other HLA-B27 positive individuals. Arthritis Rheum. 1984 Mar; 27(3):250-7.
    View in: PubMed
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