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Keywords
Last Name
Institution

Donald Elliott Ingber, M.D.,Ph.D.

TitleJudah Folkman Professor of Vascular Biology in the Department of Pathology
InstitutionChildren's Hospital Boston
DepartmentPathology
AddressWyss Institute
Center for Life Sciences, 5th Floor
3 Blackfan Circle
Boston MA 02115
Phone617/432-7044
Fax617/432-7828
Other Positions
TitleDirector, Wyss Institute for Biologically Inspired Engineering
InstitutionHarvard University
DepartmentWyss Institute


 Mentoring 
 completed student projects
Imaging Dendritic cell Dynamics within Pancreatic Islet Tumors
Summer, 06/05/06 - 09/11/06
Study of Lamellapodia Extension from Defined Surface Patterns
Summer, 05/31/02 - 09/03/02
A Novel Modality in the Development of Synaptic Connections of the Developing Central Nervous System
Summer, 05/19/00 - 08/31/00

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Huh D, Leslie DC, Matthews BD, Fraser JP, Jurek S, Hamilton GA, Thorneloe KS, McAlexander MA, Ingber DE. A Human Disease Model of Drug Toxicity-Induced Pulmonary Edema in a Lung-on-a-Chip Microdevice. Sci Transl Med. 2012 Nov 7; 4(159):159ra147.
    View in: PubMed
  2. Kim SB, Koo KI, Bae H, Dokmeci MR, Hamilton GA, Bahinski A, Kim SM, Ingber DE, Khademhosseini A. A mini-microscope for in situ monitoring of cells. Lab Chip. 2012 Oct 21; 12(20):3976-82.
    View in: PubMed
  3. Sero JE, German AE, Mammoto A, Ingber DE. Paxillin controls directional cell motility in response to physical cues. Cell Adh Migr. 2012 Nov 1; 6(6):502-8.
    View in: PubMed
  4. Mammoto T, Chen J, Jiang E, Jiang A, Smith LE, Ingber DE, Mammoto A. LRP5 regulates development of lung microvessels and alveoli through the angiopoietin-Tie2 pathway. PLoS One. 2012; 7(7):e41596.
    View in: PubMed
  5. Korin N, Kanapathipillai M, Matthews BD, Crescente M, Brill A, Mammoto T, Ghosh K, Jurek S, Bencherif SA, Bhatta D, Coskun AU, Feldman CL, Wagner DD, Ingber DE. Shear-activated nanotherapeutics for drug targeting to obstructed blood vessels. Science. 2012 Aug 10; 337(6095):738-42.
    View in: PubMed
  6. Mammoto A, Mammoto T, Ingber DE. Mechanosensitive mechanisms in transcriptional regulation. J Cell Sci. 2012 Jul 1; 125(Pt 13):3061-73.
    View in: PubMed
  7. Ingber DE, Whitesides GM. Lab on a chip: United States of America. Lab Chip. 2012 Jun 21; 12(12):2089-90.
    View in: PubMed
  8. Kanapathipillai M, Mammoto A, Mammoto T, Kang JH, Jiang E, Ghosh K, Korin N, Gibbs A, Mannix R, Ingber DE. Inhibition of mammary tumor growth using lysyl oxidase-targeting nanoparticles to modify extracellular matrix. Nano Lett. 2012 Jun 13; 12(6):3213-7.
    View in: PubMed
  9. Huh D, Torisawa YS, Hamilton GA, Kim HJ, Ingber DE. Microengineered physiological biomimicry: organs-on-chips. Lab Chip. 2012 Jun 21; 12(12):2156-64.
    View in: PubMed
  10. Kang JH, Krause S, Tobin H, Mammoto A, Kanapathipillai M, Ingber DE. A combined micromagnetic-microfluidic device for rapid capture and culture of rare circulating tumor cells. Lab Chip. 2012 Jun 21; 12(12):2175-81.
    View in: PubMed
  11. Kim HJ, Huh D, Hamilton G, Ingber DE. Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow. Lab Chip. 2012 Jun 21; 12(12):2165-74.
    View in: PubMed
  12. O'Connell DJ, Ho JW, Mammoto T, Turbe-Doan A, O'Connell JT, Haseley PS, Koo S, Kamiya N, Ingber DE, Park PJ, Maas RL. A Wnt-bmp feedback circuit controls intertissue signaling dynamics in tooth organogenesis. Sci Signal. 2012 Jan 10; 5(206):ra4.
    View in: PubMed
  13. Ghosh K, Kanapathipillai M, Korin N, McCarthy JR, Ingber DE. Polymeric nanomaterials for islet targeting and immunotherapeutic delivery. Nano Lett. 2012 Jan 11; 12(1):203-8.
    View in: PubMed
  14. Cao Y, Arbiser J, D'Amato RJ, D'Amore PA, Ingber DE, Kerbel R, Klagsbrun M, Lim S, Moses MA, Zetter B, Dvorak H, Langer R. Forty-year journey of angiogenesis translational research. Sci Transl Med. 2011 Dec 21; 3(114):114rv3.
    View in: PubMed
  15. Panigrahy D, Edin ML, Lee CR, Huang S, Bielenberg DR, Butterfield CE, Barnés CM, Mammoto A, Mammoto T, Luria A, Benny O, Chaponis DM, Dudley AC, Greene ER, Vergilio JA, Pietramaggiori G, Scherer-Pietramaggiori SS, Short SM, Seth M, Lih FB, Tomer KB, Yang J, Schwendener RA, Hammock BD, Falck JR, Manthati VL, Ingber DE, Kaipainen A, D'Amore PA, Kieran MW, Zeldin DC. Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. J Clin Invest. 2012 Jan 3; 122(1):178-91.
    View in: PubMed
  16. Sero JE, Thodeti CK, Mammoto A, Bakal C, Thomas S, Ingber DE. Paxillin mediates sensing of physical cues and regulates directional cell motility by controlling lamellipodia positioning. PLoS One. 2011; 6(12):e28303.
    View in: PubMed
  17. Fernandez JG, Ingber DE. Unexpected strength and toughness in chitosan-fibroin laminates inspired by insect cuticle. Adv Mater. 2012 Jan 24; 24(4):480-4.
    View in: PubMed
  18. Huh D, Hamilton GA, Ingber DE. From 3D cell culture to organs-on-chips. Trends Cell Biol. 2011 Dec; 21(12):745-54.
    View in: PubMed
  19. Mammoto T, Mammoto A, Torisawa YS, Tat T, Gibbs A, Derda R, Mannix R, de Bruijn M, Yung CW, Huh D, Ingber DE. Mechanochemical control of mesenchymal condensation and embryonic tooth organ formation. Dev Cell. 2011 Oct 18; 21(4):758-69.
    View in: PubMed
  20. Ingber DE. The Wyss Institute at Harvard University. IEEE Pulse. 2011 Jul-Aug; 2(4):43-6.
    View in: PubMed
  21. Derda R, Tang SK, Laromaine A, Mosadegh B, Hong E, Mwangi M, Mammoto A, Ingber DE, Whitesides GM. Multizone paper platform for 3D cell cultures. PLoS One. 2011; 6(5):e18940.
    View in: PubMed
  22. Xu Y, Bismar TA, Su J, Xu B, Kristiansen G, Varga Z, Teng L, Ingber DE, Mammoto A, Kumar R, Alaoui-Jamali MA. Filamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion. J Exp Med. 2010 Oct 25; 207(11):2421-37.
    View in: PubMed
  23. Matthews BD, Thodeti CK, Tytell JD, Mammoto A, Overby DR, Ingber DE. Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface beta1 integrins. Integr Biol (Camb). 2010 Sep; 2(9):435-42.
    View in: PubMed
  24. Huh D, Matthews BD, Mammoto A, Montoya-Zavala M, Hsin HY, Ingber DE. Reconstituting organ-level lung functions on a chip. Science. 2010 Jun 25; 328(5986):1662-8.
    View in: PubMed
  25. Liedl T, Högberg B, Tytell J, Ingber DE, Shih WM. Self-assembly of three-dimensional prestressed tensegrity structures from DNA. Nat Nanotechnol. 2010 Jul; 5(7):520-4.
    View in: PubMed
  26. Mammoto T, Ingber DE. Mechanical control of tissue and organ development. Development. 2010 May; 137(9):1407-20.
    View in: PubMed
  27. Ingber DE. From cellular mechanotransduction to biologically inspired engineering: 2009 Pritzker Award Lecture, BMES Annual Meeting October 10, 2009. Ann Biomed Eng. 2010 Mar; 38(3):1148-61.
    View in: PubMed
  28. Fainaru O, Almog N, Yung CW, Nakai K, Montoya-Zavala M, Abdollahi A, D'Amato R, Ingber DE. Tumor growth and angiogenesis are dependent on the presence of immature dendritic cells. FASEB J. 2010 May; 24(5):1411-8.
    View in: PubMed
  29. Derda R, Laromaine A, Mammoto A, Tang SK, Mammoto T, Ingber DE, Whitesides GM. Paper-supported 3D cell culture for tissue-based bioassays. Proc Natl Acad Sci U S A. 2009 Nov 3; 106(44):18457-62.
    View in: PubMed
  30. Mammoto A, Ingber DE. Cytoskeletal control of growth and cell fate switching. Curr Opin Cell Biol. 2009 Dec; 21(6):864-70.
    View in: PubMed
  31. Czakó B, Kürti L, Mammoto A, Ingber DE, Corey EJ. Discovery of potent and practical antiangiogenic agents inspired by cortistatin A. J Am Chem Soc. 2009 Jul 1; 131(25):9014-9.
    View in: PubMed
  32. Thodeti CK, Matthews B, Ravi A, Mammoto A, Ghosh K, Bracha AL, Ingber DE. TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling. Circ Res. 2009 May 8; 104(9):1123-30.
    View in: PubMed
  33. Discher D, Dong C, Fredberg JJ, Guilak F, Ingber D, Janmey P, Kamm RD, Schmid-Schönbein GW, Weinbaum S. Biomechanics: cell research and applications for the next decade. Ann Biomed Eng. 2009 May; 37(5):847-59.
    View in: PubMed
  34. Alenghat FJ, Tytell JD, Thodeti CK, Derrien A, Ingber DE. Mechanical control of cAMP signaling through integrins is mediated by the heterotrimeric Galphas protein. J Cell Biochem. 2009 Mar 1; 106(4):529-38.
    View in: PubMed
  35. Mammoto A, Connor KM, Mammoto T, Yung CW, Huh D, Aderman CM, Mostoslavsky G, Smith LE, Ingber DE. A mechanosensitive transcriptional mechanism that controls angiogenesis. Nature. 2009 Feb 26; 457(7233):1103-8.
    View in: PubMed
  36. Yung CW, Fiering J, Mueller AJ, Ingber DE. Micromagnetic-microfluidic blood cleansing device. Lab Chip. 2009 May 7; 9(9):1171-7.
    View in: PubMed
  37. Wang N, Tytell JD, Ingber DE. Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus. Nat Rev Mol Cell Biol. 2009 Jan; 10(1):75-82.
    View in: PubMed
  38. Ostuni E, Whitesides GM, Ingber DE, Chen CS. Using self-assembled monolayers to pattern ECM proteins and cells on substrates. Methods Mol Biol. 2009; 522:183-94.
    View in: PubMed
  39. Hoffmann M, Chang HH, Huang S, Ingber DE, Loeffler M, Galle J. Noise-driven stem cell and progenitor population dynamics. PLoS One. 2008; 3(8):e2922.
    View in: PubMed
  40. Ghosh K, Thodeti CK, Dudley AC, Mammoto A, Klagsbrun M, Ingber DE. Tumor-derived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro. Proc Natl Acad Sci U S A. 2008 Aug 12; 105(32):11305-10.
    View in: PubMed
  41. Shimizu A, Mammoto A, Italiano JE, Pravda E, Dudley AC, Ingber DE, Klagsbrun M. ABL2/ARG tyrosine kinase mediates SEMA3F-induced RhoA inactivation and cytoskeleton collapse in human glioma cells. J Biol Chem. 2008 Oct 3; 283(40):27230-8.
    View in: PubMed
  42. Luo Y, Xu X, Lele T, Kumar S, Ingber DE. A multi-modular tensegrity model of an actin stress fiber. J Biomech. 2008 Aug 7; 41(11):2379-87.
    View in: PubMed
  43. Ingber DE. Tensegrity and mechanotransduction. J Bodyw Mov Ther. 2008 Jul; 12(3):198-200.
    View in: PubMed
  44. Gee EP, Ingber DE, Stultz CM. Fibronectin unfolding revisited: modeling cell traction-mediated unfolding of the tenth type-III repeat. PLoS One. 2008; 3(6):e2373.
    View in: PubMed
  45. Chang HH, Hemberg M, Barahona M, Ingber DE, Huang S. Transcriptome-wide noise controls lineage choice in mammalian progenitor cells. Nature. 2008 May 22; 453(7194):544-7.
    View in: PubMed
  46. Mammoto A, Mammoto T, Ingber DE. Rho signaling and mechanical control of vascular development. Curr Opin Hematol. 2008 May; 15(3):228-34.
    View in: PubMed
  47. Fredenburgh LE, Liang OD, Macias AA, Polte TR, Liu X, Riascos DF, Chung SW, Schissel SL, Ingber DE, Mitsialis SA, Kourembanas S, Perrella MA. Absence of cyclooxygenase-2 exacerbates hypoxia-induced pulmonary hypertension and enhances contractility of vascular smooth muscle cells. Circulation. 2008 Apr 22; 117(16):2114-22.
    View in: PubMed
  48. Ingber DE. Can cancer be reversed by engineering the tumor microenvironment? Semin Cancer Biol. 2008 Oct; 18(5):356-64.
    View in: PubMed
  49. Lele TP, Thodeti CK, Pendse J, Ingber DE. Investigating complexity of protein-protein interactions in focal adhesions. Biochem Biophys Res Commun. 2008 May 9; 369(3):929-34.
    View in: PubMed
  50. Nauli SM, Kawanabe Y, Kaminski JJ, Pearce WJ, Ingber DE, Zhou J. Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1. Circulation. 2008 Mar 4; 117(9):1161-71.
    View in: PubMed
  51. Ingber DE. Tensegrity-based mechanosensing from macro to micro. Prog Biophys Mol Biol. 2008 Jun-Jul; 97(2-3):163-79.
    View in: PubMed
  52. Xia N, Thodeti CK, Hunt TP, Xu Q, Ho M, Whitesides GM, Westervelt R, Ingber DE. Directional control of cell motility through focal adhesion positioning and spatial control of Rac activation. FASEB J. 2008 Jun; 22(6):1649-59.
    View in: PubMed
  53. Mammoto A, Sero JE, Mammoto T, Ingber DE. Methods for studying mechanical control of angiogenesis by the cytoskeleton and extracellular matrix. Methods Enzymol. 2008; 443:227-59.
    View in: PubMed
  54. Mannix RJ, Kumar S, Cassiola F, Montoya-Zavala M, Feinstein E, Prentiss M, Ingber DE. Nanomagnetic actuation of receptor-mediated signal transduction. Nat Nanotechnol. 2008 Jan; 3(1):36-40.
    View in: PubMed
  55. Wilson NR, Ty MT, Ingber DE, Sur M, Liu G. Synaptic reorganization in scaled networks of controlled size. J Neurosci. 2007 Dec 12; 27(50):13581-9.
    View in: PubMed
  56. Pietramaggiori G, Liu P, Scherer SS, Kaipainen A, Prsa MJ, Mayer H, Newalder J, Alperovich M, Mentzer SJ, Konerding MA, Huang S, Ingber DE, Orgill DP. Tensile forces stimulate vascular remodeling and epidermal cell proliferation in living skin. Ann Surg. 2007 Nov; 246(5):896-902.
    View in: PubMed
  57. Parker KK, Ingber DE. Extracellular matrix, mechanotransduction and structural hierarchies in heart tissue engineering. Philos Trans R Soc Lond B Biol Sci. 2007 Aug 29; 362(1484):1267-79.
    View in: PubMed
  58. Ghosh K, Ingber DE. Micromechanical control of cell and tissue development: implications for tissue engineering. Adv Drug Deliv Rev. 2007 Nov 10; 59(13):1306-18.
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  59. Stamenovic D, Rosenblatt N, Montoya-Zavala M, Matthews BD, Hu S, Suki B, Wang N, Ingber DE. Rheological behavior of living cells is timescale-dependent. Biophys J. 2007 Oct 15; 93(8):L39-41.
    View in: PubMed
  60. Mammoto T, Parikh SM, Mammoto A, Gallagher D, Chan B, Mostoslavsky G, Ingber DE, Sukhatme VP. Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo. J Biol Chem. 2007 Aug 17; 282(33):23910-8.
    View in: PubMed
  61. Ingber DE, Levin M. What lies at the interface of regenerative medicine and developmental biology? Development. 2007 Jul; 134(14):2541-7.
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  62. Chen Z, Naveiras O, Balduini A, Mammoto A, Conti MA, Adelstein RS, Ingber D, Daley GQ, Shivdasani RA. The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway. Blood. 2007 Jul 1; 110(1):171-9.
    View in: PubMed
  63. Polte TR, Shen M, Karavitis J, Montoya M, Pendse J, Xia S, Mazur E, Ingber DE. Nanostructured magnetizable materials that switch cells between life and death. Biomaterials. 2007 Jun; 28(17):2783-90.
    View in: PubMed
  64. Mammoto A, Huang S, Ingber DE. Filamin links cell shape and cytoskeletal structure to Rho regulation by controlling accumulation of p190RhoGAP in lipid rafts. J Cell Sci. 2007 Feb 1; 120(Pt 3):456-67.
    View in: PubMed
  65. Lele TP, Sero JE, Matthews BD, Kumar S, Xia S, Montoya-Zavala M, Polte T, Overby D, Wang N, Ingber DE. Tools to study cell mechanics and mechanotransduction. Methods Cell Biol. 2007; 83:443-72.
    View in: PubMed
  66. Lele T, Wagner SR, Nickerson JA, Ingber DE. Methods for measuring rates of protein binding to insoluble scaffolds in living cells: histone H1-chromatin interactions. J Cell Biochem. 2006 Dec 1; 99(5):1334-42.
    View in: PubMed
  67. Ingber DE, Mow VC, Butler D, Niklason L, Huard J, Mao J, Yannas I, Kaplan D, Vunjak-Novakovic G. Tissue engineering and developmental biology: going biomimetic. Tissue Eng. 2006 Dec; 12(12):3265-83.
    View in: PubMed
  68. Xia N, Hunt TP, Mayers BT, Alsberg E, Whitesides GM, Westervelt RM, Ingber DE. Combined microfluidic-micromagnetic separation of living cells in continuous flow. Biomed Microdevices. 2006 Dec; 8(4):299-308.
    View in: PubMed
  69. Dandapani SV, Sugimoto H, Matthews BD, Kolb RJ, Sinha S, Gerszten RE, Zhou J, Ingber DE, Kalluri R, Pollak MR. Alpha-actinin-4 is required for normal podocyte adhesion. J Biol Chem. 2007 Jan 5; 282(1):467-77.
    View in: PubMed
  70. Alsberg E, Feinstein E, Joy MP, Prentiss M, Ingber DE. Magnetically-guided self-assembly of fibrin matrices with ordered nano-scale structure for tissue engineering. Tissue Eng. 2006 Nov; 12(11):3247-56.
    View in: PubMed
  71. Sharp ZD, Mancini MG, Hinojos CA, Dai F, Berno V, Szafran AT, Smith KP, Lele TP, Lele TT, Ingber DE, Mancini MA. Estrogen-receptor-alpha exchange and chromatin dynamics are ligand- and domain-dependent. J Cell Sci. 2006 Oct 1; 119(Pt 19):4101-16.
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  72. Yokouchi K, Numaguchi Y, Kubota R, Ishii M, Imai H, Murakami R, Ogawa Y, Kondo T, Okumura K, Ingber DE, Murohara T. l-Caldesmon regulates proliferation and migration of vascular smooth muscle cells and inhibits neointimal formation after angioplasty. Arterioscler Thromb Vasc Biol. 2006 Oct; 26(10):2231-7.
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  73. Brangwynne CP, MacKintosh FC, Kumar S, Geisse NA, Talbot J, Mahadevan L, Parker KK, Ingber DE, Weitz DA. Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcement. J Cell Biol. 2006 Jun 5; 173(5):733-41.
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  74. Ingber DE. Cellular mechanotransduction: putting all the pieces together again. FASEB J. 2006 May; 20(7):811-27.
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  75. Lele TP, Thodeti CK, Ingber DE. Force meets chemistry: analysis of mechanochemical conversion in focal adhesions using fluorescence recovery after photobleaching. J Cell Biochem. 2006 Apr 15; 97(6):1175-83.
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  76. Nauli SM, Rossetti S, Kolb RJ, Alenghat FJ, Consugar MB, Harris PC, Ingber DE, Loghman-Adham M, Zhou J. Loss of polycystin-1 in human cyst-lining epithelia leads to ciliary dysfunction. J Am Soc Nephrol. 2006 Apr; 17(4):1015-25.
    View in: PubMed
  77. Lele TP, Pendse J, Kumar S, Salanga M, Karavitis J, Ingber DE. Mechanical forces alter zyxin unbinding kinetics within focal adhesions of living cells. J Cell Physiol. 2006 Apr; 207(1):187-94.
    View in: PubMed
  78. Chang HH, Oh PY, Ingber DE, Huang S. Multistable and multistep dynamics in neutrophil differentiation. BMC Cell Biol. 2006; 7:11.
    View in: PubMed
  79. Kumar S, Maxwell IZ, Heisterkamp A, Polte TR, Lele TP, Salanga M, Mazur E, Ingber DE. Viscoelastic retraction of single living stress fibers and its impact on cell shape, cytoskeletal organization, and extracellular matrix mechanics. Biophys J. 2006 May 15; 90(10):3762-73.
    View in: PubMed
  80. Matthews BD, Overby DR, Mannix R, Ingber DE. Cellular adaptation to mechanical stress: role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels. J Cell Sci. 2006 Feb 1; 119(Pt 3):508-18.
    View in: PubMed
  81. Huang S, Ingber DE. A non-genetic basis for cancer progression and metastasis: self-organizing attractors in cell regulatory networks. Breast Dis. 2006-2007; 26:27-54.
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  82. Guo Y, Eichler GS, Feng Y, Ingber DE, Huang S. Towards a holistic, yet gene-centered analysis of gene expression profiles: a case study of human lung cancers. J Biomed Biotechnol. 2006; 2006(5):69141.
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  83. Ingber DE. Mechanical control of tissue morphogenesis during embryological development. Int J Dev Biol. 2006; 50(2-3):255-66.
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  84. Barnés CM, Huang S, Kaipainen A, Sanoudou D, Chen EJ, Eichler GS, Guo Y, Yu Y, Ingber DE, Mulliken JB, Beggs AH, Folkman J, Fishman SJ. Evidence by molecular profiling for a placental origin of infantile hemangioma. Proc Natl Acad Sci U S A. 2005 Dec 27; 102(52):19097-102.
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  85. Alon R, Feigelson SW, Manevich E, Rose DM, Schmitz J, Overby DR, Winter E, Grabovsky V, Shinder V, Matthews BD, Sokolovsky-Eisenberg M, Ingber DE, Benoit M, Ginsberg MH. Alpha4beta1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the alpha4-cytoplasmic domain. J Cell Biol. 2005 Dec 19; 171(6):1073-84.
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  86. Lele TP, Ingber DE. A mathematical model to determine molecular kinetic rate constants under non-steady state conditions using fluorescence recovery after photobleaching (FRAP). Biophys Chem. 2006 Mar 1; 120(1):32-5.
    View in: PubMed
  87. Sanchez-Esteban J, Wang Y, Filardo EJ, Rubin LP, Ingber DE. Integrins beta1, alpha6, and alpha3 contribute to mechanical strain-induced differentiation of fetal lung type II epithelial cells via distinct mechanisms. Am J Physiol Lung Cell Mol Physiol. 2006 Feb; 290(2):L343-50.
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  88. Brock AL, Ingber DE. Control of the direction of lamellipodia extension through changes in the balance between Rac and Rho activities. Mol Cell Biomech. 2005 Sep; 2(3):135-43.
    View in: PubMed
  89. Huang S, Ingber DE. Cell tension, matrix mechanics, and cancer development. Cancer Cell. 2005 Sep; 8(3):175-6.
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  90. Ingber DE. Mechanical control of tissue growth: function follows form. Proc Natl Acad Sci U S A. 2005 Aug 16; 102(33):11571-2.
    View in: PubMed
  91. Huang S, Brangwynne CP, Parker KK, Ingber DE. Symmetry-breaking in mammalian cell cohort migration during tissue pattern formation: role of random-walk persistence. Cell Motil Cytoskeleton. 2005 Aug; 61(4):201-13.
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  92. Ingber DE. Tissue adaptation to mechanical forces in healthy, injured and aging tissues. Scand J Med Sci Sports. 2005 Aug; 15(4):199-201.
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  93. Joy MP, Brock A, Ingber DE, Huang S. High-betweenness proteins in the yeast protein interaction network. J Biomed Biotechnol. 2005 Jun 30; 2005(2):96-103.
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  94. Heisterkamp A, Maxwell IZ, Mazur E, Underwood JM, Nickerson JA, Kumar S, Ingber DE. Pulse energy dependence of subcellular dissection by femtosecond laser pulses. Opt Express. 2005 May 16; 13(10):3690-6.
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  95. Huang S, Eichler G, Bar-Yam Y, Ingber DE. Cell fates as high-dimensional attractor states of a complex gene regulatory network. Phys Rev Lett. 2005 Apr 1; 94(12):128701.
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  96. Overby DR, Matthews BD, Alsberg E, Ingber DE. Novel dynamic rheological behavior of individual focal adhesions measured within single cells using electromagnetic pulling cytometry. Acta Biomater. 2005 May; 1(3):295-303.
    View in: PubMed
  97. Short SM, Derrien A, Narsimhan RP, Lawler J, Ingber DE, Zetter BR. Inhibition of endothelial cell migration by thrombospondin-1 type-1 repeats is mediated by beta1 integrins. J Cell Biol. 2005 Feb 14; 168(4):643-53.
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  98. Moore KA, Polte T, Huang S, Shi B, Alsberg E, Sunday ME, Ingber DE. Control of basement membrane remodeling and epithelial branching morphogenesis in embryonic lung by Rho and cytoskeletal tension. Dev Dyn. 2005 Feb; 232(2):268-81.
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  99. Shen N, Datta D, Schaffer CB, LeDuc P, Ingber DE, Mazur E. Ablation of cytoskeletal filaments and mitochondria in live cells using a femtosecond laser nanoscissor. Mech Chem Biosyst. 2005; 2(1):17-25.
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  100. Alenghat FJ, Nauli SM, Kolb R, Zhou J, Ingber DE. Global cytoskeletal control of mechanotransduction in kidney epithelial cells. Exp Cell Res. 2004 Nov 15; 301(1):23-30.
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  101. Saxena V, Hwang CW, Huang S, Eichbaum Q, Ingber D, Orgill DP. Vacuum-assisted closure: microdeformations of wounds and cell proliferation. Plast Reconstr Surg. 2004 Oct; 114(5):1086-96; discussion 1097-8.
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  102. Lele T, Oh P, Nickerson JA, Ingber DE. An improved mathematical approach for determination of molecular kinetics in living cells with FRAP. Mech Chem Biosyst. 2004 Sep; 1(3):181-90.
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  103. Mammoto A, Huang S, Moore K, Oh P, Ingber DE. Role of RhoA, mDia, and ROCK in cell shape-dependent control of the Skp2-p27kip1 pathway and the G1/S transition. J Biol Chem. 2004 Jun 18; 279(25):26323-30.
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  104. Sultan C, Stamenovic D, Ingber DE. A computational tensegrity model predicts dynamic rheological behaviors in living cells. Ann Biomed Eng. 2004 Apr; 32(4):520-30.
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  105. Ingber DE. The mechanochemical basis of cell and tissue regulation. Mech Chem Biosyst. 2004 Mar; 1(1):53-68.
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  106. Polte TR, Eichler GS, Wang N, Ingber DE. Extracellular matrix controls myosin light chain phosphorylation and cell contractility through modulation of cell shape and cytoskeletal prestress. Am J Physiol Cell Physiol. 2004 Mar; 286(3):C518-28.
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  107. Matthews BD, Overby DR, Alenghat FJ, Karavitis J, Numaguchi Y, Allen PG, Ingber DE. Mechanical properties of individual focal adhesions probed with a magnetic microneedle. Biochem Biophys Res Commun. 2004 Jan 16; 313(3):758-64.
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  108. Eichler GS, Huang S, Ingber DE. Gene Expression Dynamics Inspector (GEDI): for integrative analysis of expression profiles. Bioinformatics. 2003 Nov 22; 19(17):2321-2.
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  109. Chen CS, Alonso JL, Ostuni E, Whitesides GM, Ingber DE. Cell shape provides global control of focal adhesion assembly. Biochem Biophys Res Commun. 2003 Jul 25; 307(2):355-61.
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  110. Brock A, Huang S, Ingber DE. Identification of a distinct class of cytoskeleton-associated mRNAs using microarray technology. BMC Cell Biol. 2003 Jul 8; 4:6.
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  111. Hu S, Chen J, Fabry B, Numaguchi Y, Gouldstone A, Ingber DE, Fredberg JJ, Butler JP, Wang N. Intracellular stress tomography reveals stress focusing and structural anisotropy in cytoskeleton of living cells. Am J Physiol Cell Physiol. 2003 Nov; 285(5):C1082-90.
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  112. Ingber DE. Tensegrity II. How structural networks influence cellular information processing networks. J Cell Sci. 2003 Apr 15; 116(Pt 8):1397-408.
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  113. Ingber DE. Tensegrity I. Cell structure and hierarchical systems biology. J Cell Sci. 2003 Apr 1; 116(Pt 7):1157-73.
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  114. Brock A, Chang E, Ho CC, LeDuc P, Jiang X, Whitesides GM, Ingber DE. Geometric determinants of directional cell motility revealed using microcontact printing. Langmuir. 2003 Mar 4; 19(5):1611-7.
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  115. Ingber DE. Mechanosensation through integrins: cells act locally but think globally. Proc Natl Acad Sci U S A. 2003 Feb 18; 100(4):1472-4.
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  116. Takayama S, Ostuni E, LeDuc P, Naruse K, Ingber DE, Whitesides GM. Selective chemical treatment of cellular microdomains using multiple laminar streams. Chem Biol. 2003 Feb; 10(2):123-30.
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  117. Nauli SM, Alenghat FJ, Luo Y, Williams E, Vassilev P, Li X, Elia AE, Lu W, Brown EM, Quinn SJ, Ingber DE, Zhou J. Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat Genet. 2003 Feb; 33(2):129-37.
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  118. Ingber DE. Mechanobiology and diseases of mechanotransduction. Ann Med. 2003; 35(8):564-77.
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  119. Numaguchi Y, Huang S, Polte TR, Eichler GS, Wang N, Ingber DE. Caldesmon-dependent switching between capillary endothelial cell growth and apoptosis through modulation of cell shape and contractility. Angiogenesis. 2003; 6(1):55-64.
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  120. Ingber DE. Cancer as a disease of epithelial-mesenchymal interactions and extracellular matrix regulation. Differentiation. 2002 Dec; 70(9-10):547-60.
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  121. Ingber DE. Mechanical signaling and the cellular response to extracellular matrix in angiogenesis and cardiovascular physiology. Circ Res. 2002 Nov 15; 91(10):877-87.
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  122. Parker KK, Brock AL, Brangwynne C, Mannix RJ, Wang N, Ostuni E, Geisse NA, Adams JC, Whitesides GM, Ingber DE. Directional control of lamellipodia extension by constraining cell shape and orienting cell tractional forces. FASEB J. 2002 Aug; 16(10):1195-204.
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  123. Castedo M, Roumier T, Blanco J, Ferri KF, Barretina J, Tintignac LA, Andreau K, Perfettini JL, Amendola A, Nardacci R, Leduc P, Ingber DE, Druillennec S, Roques B, Leibovitch SA, Vilella-Bach M, Chen J, Este JA, Modjtahedi N, Piacentini M, Kroemer G. Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope. EMBO J. 2002 Aug 1; 21(15):4070-80.
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  124. Damsky C, Heidaran M, Bottaro D, Crossin K, Ducy P, Ingber D. Molecular signaling: breakout session summary. Ann N Y Acad Sci. 2002 Jun; 961:164-7.
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  125. Wang N, Ostuni E, Whitesides GM, Ingber DE. Micropatterning tractional forces in living cells. Cell Motil Cytoskeleton. 2002 Jun; 52(2):97-106.
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  126. Stamenovic D, Ingber DE. Models of cytoskeletal mechanics of adherent cells. Biomech Model Mechanobiol. 2002 Jun; 1(1):95-108.
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  127. Ingber D. Mechanical signaling. Ann N Y Acad Sci. 2002 Jun; 961:162-3.
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  128. Moore KA, Huang S, Kong Y, Sunday ME, Ingber DE. Control of embryonic lung branching morphogenesis by the Rho activator, cytotoxic necrotizing factor 1. J Surg Res. 2002 May 15; 104(2):95-100.
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  129. Huang S, Ingber DE. A discrete cell cycle checkpoint in late G(1) that is cytoskeleton-dependent and MAP kinase (Erk)-independent. Exp Cell Res. 2002 May 1; 275(2):255-64.
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  130. Alenghat FJ, Ingber DE. Mechanotransduction: all signals point to cytoskeleton, matrix, and integrins. Sci STKE. 2002 Feb 12; 2002(119):pe6.
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  131. Goldmann WH, Ingber DE. Intact vinculin protein is required for control of cell shape, cell mechanics, and rac-dependent lamellipodia formation. Biochem Biophys Res Commun. 2002 Jan 18; 290(2):749-55.
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  132. LeDuc P, Ostuni E, Whitesides G, Ingber D. Use of micropatterned adhesive surfaces for control of cell behavior. Methods Cell Biol. 2002; 69:385-401.
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  133. Flusberg DA, Numaguchi Y, Ingber DE. Cooperative control of Akt phosphorylation, bcl-2 expression, and apoptosis by cytoskeletal microfilaments and microtubules in capillary endothelial cells. Mol Biol Cell. 2001 Oct; 12(10):3087-94.
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  134. Wang N, Naruse K, Stamenovic D, Fredberg JJ, Mijailovich SM, Tolic-Nørrelykke IM, Polte T, Mannix R, Ingber DE. Mechanical behavior in living cells consistent with the tensegrity model. Proc Natl Acad Sci U S A. 2001 Jul 3; 98(14):7765-70.
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  135. Takayama S, Ostuni E, LeDuc P, Naruse K, Ingber DE, Whitesides GM. Subcellular positioning of small molecules. Nature. 2001 Jun 28; 411(6841):1016.
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  136. Whitesides GM, Ostuni E, Takayama S, Jiang X, Ingber DE. Soft lithography in biology and biochemistry. Annu Rev Biomed Eng. 2001; 3:335-73.
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  137. Ingber DE. The origin of cellular life. Bioessays. 2000 Dec; 22(12):1160-70.
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  138. Huang S, Ingber DE. Shape-dependent control of cell growth, differentiation, and apoptosis: switching between attractors in cell regulatory networks. Exp Cell Res. 2000 Nov 25; 261(1):91-103.
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  139. Ferri KF, Jacotot E, Leduc P, Geuskens M, Ingber DE, Kroemer G. Apoptosis of syncytia induced by the HIV-1-envelope glycoprotein complex: influence of cell shape and size. Exp Cell Res. 2000 Nov 25; 261(1):119-26.
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  140. Yan L, Moses MA, Huang S, Ingber DE. Adhesion-dependent control of matrix metalloproteinase-2 activation in human capillary endothelial cells. J Cell Sci. 2000 Nov; 113 ( Pt 22):3979-87.
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  141. Alenghat FJ, Fabry B, Tsai KY, Goldmann WH, Ingber DE. Analysis of cell mechanics in single vinculin-deficient cells using a magnetic tweezer. Biochem Biophys Res Commun. 2000 Oct 14; 277(1):93-9.
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  142. Brangwynne C, Huang S, Parker KK, Ingber DE, Ostuni E. Symmetry breaking in cultured mammalian cells. In Vitro Cell Dev Biol Anim. 2000 Oct; 36(9):563-5.
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  143. Ingber DE. Opposing views on tensegrity as a structural framework for understanding cell mechanics. J Appl Physiol. 2000 Oct; 89(4):1663-70.
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  144. Meyer CJ, Alenghat FJ, Rim P, Fong JH, Fabry B, Ingber DE. Mechanical control of cyclic AMP signalling and gene transcription through integrins. Nat Cell Biol. 2000 Sep; 2(9):666-8.
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  145. Chiu DT, Jeon NL, Huang S, Kane RS, Wargo CJ, Choi IS, Ingber DE, Whitesides GM. Patterned deposition of cells and proteins onto surfaces by using three-dimensional microfluidic systems. Proc Natl Acad Sci U S A. 2000 Mar 14; 97(6):2408-13.
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  146. Chen CS, Ostuni E, Whitesides GM, Ingber DE. Using self-assembled monolayers to pattern ECM proteins and cells on substrates. Methods Mol Biol. 2000; 139:209-19.
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  147. Kane RS, Takayama S, Ostuni E, Ingber DE, Whitesides GM. Patterning proteins and cells using soft lithography. Biomaterials. 1999 Dec; 20(23-24):2363-76.
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  148. Zhao H, Bojanowski K, Ingber DE, Panigrahy D, Pepper MS, Montesano R, Shing Y. New role for tRNA and its fragment purified from human urinary bladder carcinoma conditioned medium: inhibition of endothelial cell growth. J Cell Biochem. 1999 Nov; 76(1):109-17.
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  149. Gechtman Z, Alonso JL, Raab G, Ingber DE, Klagsbrun M. The shedding of membrane-anchored heparin-binding epidermal-like growth factor is regulated by the Raf/mitogen-activated protein kinase cascade and by cell adhesion and spreading. J Biol Chem. 1999 Oct 1; 274(40):28828-35.
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  150. Huang S, Ingber DE. The structural and mechanical complexity of cell-growth control. Nat Cell Biol. 1999 Sep; 1(5):E131-8.
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  151. Dike LE, Chen CS, Mrksich M, Tien J, Whitesides GM, Ingber DE. Geometric control of switching between growth, apoptosis, and differentiation during angiogenesis using micropatterned substrates. In Vitro Cell Dev Biol Anim. 1999 Sep; 35(8):441-8.
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  152. Chen CS, Brangwynne C, Ingber DE. Pictures in cell biology: squaring up to the cell-shape debate. Trends Cell Biol. 1999 Jul; 9(7):283.
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  153. Ingber D. How cells (might) sense microgravity. FASEB J. 1999; 13 Suppl:S3-15.
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  154. Chen CS, Ingber DE. Tensegrity and mechanoregulation: from skeleton to cytoskeleton. Osteoarthritis Cartilage. 1999 Jan; 7(1):81-94.
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  155. Huang S, Chen CS, Ingber DE. Control of cyclin D1, p27(Kip1), and cell cycle progression in human capillary endothelial cells by cell shape and cytoskeletal tension. Mol Biol Cell. 1998 Nov; 9(11):3179-93.
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  156. Cai S, Pestic-Dragovich L, O'Donnell ME, Wang N, Ingber D, Elson E, De Lanerolle P. Regulation of cytoskeletal mechanics and cell growth by myosin light chain phosphorylation. Am J Physiol. 1998 Nov; 275(5 Pt 1):C1349-56.
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  157. Bojanowski K, Ingber DE. Ionic control of chromosome architecture in living and permeabilized cells. Exp Cell Res. 1998 Oct 10; 244(1):286-94.
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  158. Eckes B, Dogic D, Colucci-Guyon E, Wang N, Maniotis A, Ingber D, Merckling A, Langa F, Aumailley M, Delouvée A, Koteliansky V, Babinet C, Krieg T. Impaired mechanical stability, migration and contractile capacity in vimentin-deficient fibroblasts. J Cell Sci. 1998 Jul; 111 ( Pt 13):1897-907.
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  159. Ingber DE. Cellular basis of mechanotransduction. Biol Bull. 1998 Jun; 194(3):323-5; discussion 325-7.
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  160. Bojanowski K, Maniotis AJ, Plisov S, Larsen AK, Ingber DE. DNA topoisomerase II can drive changes in higher order chromosome architecture without enzymatically modifying DNA. J Cell Biochem. 1998 May 1; 69(2):127-42.
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  161. Pourati J, Maniotis A, Spiegel D, Schaffer JL, Butler JP, Fredberg JJ, Ingber DE, Stamenovic D, Wang N. Is cytoskeletal tension a major determinant of cell deformability in adherent endothelial cells? Am J Physiol. 1998 May; 274(5 Pt 1):C1283-9.
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  162. Chen CS, Mrksich M, Huang S, Whitesides GM, Ingber DE. Micropatterned surfaces for control of cell shape, position, and function. Biotechnol Prog. 1998 May-Jun; 14(3):356-63.
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  163. Chicurel ME, Singer RH, Meyer CJ, Ingber DE. Integrin binding and mechanical tension induce movement of mRNA and ribosomes to focal adhesions. Nature. 1998 Apr 16; 392(6677):730-3.
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  164. Chicurel ME, Chen CS, Ingber DE. Cellular control lies in the balance of forces. Curr Opin Cell Biol. 1998 Apr; 10(2):232-9.
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  165. Ingber DE. The architecture of life. Sci Am. 1998 Jan; 278(1):48-57.
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  166. Lee KM, Tsai KY, Wang N, Ingber DE. Extracellular matrix and pulmonary hypertension: control of vascular smooth muscle cell contractility. Am J Physiol. 1998 Jan; 274(1 Pt 2):H76-82.
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  167. Ingber D. In search of cellular control: signal transduction in context. J Cell Biochem Suppl. 1998; 30-31:232-7.
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  168. Mrksich M, Dike LE, Tien J, Ingber DE, Whitesides GM. Using microcontact printing to pattern the attachment of mammalian cells to self-assembled monolayers of alkanethiolates on transparent films of gold and silver. Exp Cell Res. 1997 Sep 15; 235(2):305-13.
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  169. Ingber DE. Integrins, tensegrity, and mechanotransduction. Gravit Space Biol Bull. 1997 Jun; 10(2):49-55.
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  170. Chen CS, Mrksich M, Huang S, Whitesides GM, Ingber DE. Geometric control of cell life and death. Science. 1997 May 30; 276(5317):1425-8.
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  171. Planus E, Barlovatz-Meimon G, Rogers RA, Bonavaud S, Ingber DE, Wang N. Binding of urokinase to plasminogen activator inhibitor type-1 mediates cell adhesion and spreading. J Cell Sci. 1997 May; 110 ( Pt 9):1091-8.
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  172. Maniotis AJ, Bojanowski K, Ingber DE. Mechanical continuity and reversible chromosome disassembly within intact genomes removed from living cells. J Cell Biochem. 1997 Apr; 65(1):114-30.
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  173. Ezzell RM, Goldmann WH, Wang N, Parashurama N, Parasharama N, Ingber DE. Vinculin promotes cell spreading by mechanically coupling integrins to the cytoskeleton. Exp Cell Res. 1997 Feb 25; 231(1):14-26.
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  174. Maniotis AJ, Chen CS, Ingber DE. Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure. Proc Natl Acad Sci U S A. 1997 Feb 4; 94(3):849-54.
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  175. Tagawa H, Wang N, Narishige T, Ingber DE, Zile MR, Cooper G. Cytoskeletal mechanics in pressure-overload cardiac hypertrophy. Circ Res. 1997 Feb; 80(2):281-9.
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  176. Ingber DE. Tensegrity: the architectural basis of cellular mechanotransduction. Annu Rev Physiol. 1997; 59:575-99.
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  177. Dike LE, Ingber DE. Integrin-dependent induction of early growth response genes in capillary endothelial cells. J Cell Sci. 1996 Dec; 109 ( Pt 12):2855-63.
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  178. Mrksich M, Chen CS, Xia Y, Dike LE, Ingber DE, Whitesides GM. Controlling cell attachment on contoured surfaces with self-assembled monolayers of alkanethiolates on gold. Proc Natl Acad Sci U S A. 1996 Oct 1; 93(20):10775-8.
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  179. Stamenovic D, Fredberg JJ, Wang N, Butler JP, Ingber DE. A microstructural approach to cytoskeletal mechanics based on tensegrity. J Theor Biol. 1996 Jul 21; 181(2):125-36.
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  180. McNamee HP, Liley HG, Ingber DE. Integrin-dependent control of inositol lipid synthesis in vascular endothelial cells and smooth muscle cells. Exp Cell Res. 1996 Apr 10; 224(1):116-22.
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  181. Fong JH, Ingber DE. Modulation of adhesion-dependent cAMP signaling by echistatin and alendronate. Biochem Biophys Res Commun. 1996 Apr 5; 221(1):19-24.
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  182. Yoshida M, Westlin WF, Wang N, Ingber DE, Rosenzweig A, Resnick N, Gimbrone MA. Leukocyte adhesion to vascular endothelium induces E-selectin linkage to the actin cytoskeleton. J Cell Biol. 1996 Apr; 133(2):445-55.
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  183. Kieffer JD, Plopper G, Ingber DE, Hartwig JH, Kupper TS. Direct binding of F actin to the cytoplasmic domain of the alpha 2 integrin chain in vitro. Biochem Biophys Res Commun. 1995 Dec 14; 217(2):466-74.
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  184. Ingber DE, Prusty D, Sun Z, Betensky H, Wang N. Cell shape, cytoskeletal mechanics, and cell cycle control in angiogenesis. J Biomech. 1995 Dec; 28(12):1471-84.
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  185. Plopper GE, McNamee HP, Dike LE, Bojanowski K, Ingber DE. Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex. Mol Biol Cell. 1995 Oct; 6(10):1349-65.
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  186. Wang N, Ingber DE. Probing transmembrane mechanical coupling and cytomechanics using magnetic twisting cytometry. Biochem Cell Biol. 1995 Jul-Aug; 73(7-8):327-35.
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  187. Mooney DJ, Langer R, Ingber DE. Cytoskeletal filament assembly and the control of cell spreading and function by extracellular matrix. J Cell Sci. 1995 Jun; 108 ( Pt 6):2311-20.
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  188. Mooney DJ, Hansen LK, Langer R, Vacanti JP, Ingber DE. Extracellular matrix controls tubulin monomer levels in hepatocytes by regulating protein turnover. Mol Biol Cell. 1994 Dec; 5(12):1281-8.
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  189. Hansen LK, Mooney DJ, Vacanti JP, Ingber DE. Integrin binding and cell spreading on extracellular matrix act at different points in the cell cycle to promote hepatocyte growth. Mol Biol Cell. 1994 Sep; 5(9):967-75.
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  190. Yang MB, Vacanti JP, Ingber DE. Hollow fibers for hepatocyte encapsulation and transplantation: studies of survival and function in rats. Cell Transplant. 1994 Sep-Oct; 3(5):373-85.
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  191. Wang N, Ingber DE. Control of cytoskeletal mechanics by extracellular matrix, cell shape, and mechanical tension. Biophys J. 1994 Jun; 66(6):2181-9.
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  192. Singhvi R, Kumar A, Lopez GP, Stephanopoulos GN, Wang DI, Whitesides GM, Ingber DE. Engineering cell shape and function. Science. 1994 Apr 29; 264(5159):696-8.
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  193. Wong JY, Langer R, Ingber DE. Electrically conducting polymers can noninvasively control the shape and growth of mammalian cells. Proc Natl Acad Sci U S A. 1994 Apr 12; 91(8):3201-4.
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  194. Schwartz MA, Ingber DE. Integrating with integrins. Mol Biol Cell. 1994 Apr; 5(4):389-93.
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  195. Kusaka M, Sudo K, Matsutani E, Kozai Y, Marui S, Fujita T, Ingber D, Folkman J. Cytostatic inhibition of endothelial cell growth by the angiogenesis inhibitor TNP-470 (AGM-1470). Br J Cancer. 1994 Feb; 69(2):212-6.
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  196. Ingber DE, Dike L, Hansen L, Karp S, Liley H, Maniotis A, McNamee H, Mooney D, Plopper G, Sims J, et al. Cellular tensegrity: exploring how mechanical changes in the cytoskeleton regulate cell growth, migration, and tissue pattern during morphogenesis. Int Rev Cytol. 1994; 150:173-224.
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  197. Ingber DE. The riddle of morphogenesis: a question of solution chemistry or molecular cell engineering? Cell. 1993 Dec 31; 75(7):1249-52.
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  198. Mikos AG, Sarakinos G, Lyman MD, Ingber DE, Vacanti JP, Langer R. Prevascularization of porous biodegradable polymers. Biotechnol Bioeng. 1993 Sep 5; 42(6):716-23.
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  199. Plopper G, Ingber DE. Rapid induction and isolation of focal adhesion complexes. Biochem Biophys Res Commun. 1993 Jun 15; 193(2):571-8.
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  200. Wang N, Butler JP, Ingber DE. Mechanotransduction across the cell surface and through the cytoskeleton. Science. 1993 May 21; 260(5111):1124-7.
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  201. McNamee HP, Ingber DE, Schwartz MA. Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown. J Cell Biol. 1993 May; 121(3):673-8.
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  202. Ingber DE. Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton. J Cell Sci. 1993 Mar; 104 ( Pt 3):613-27.
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  203. Fontaine M, Hansen LK, Thompson S, Uyama S, Ingber DE, Langer R, Vacanti JP. Transplantation of genetically altered hepatocytes using cell-polymer constructs. Transplant Proc. 1993 Feb; 25(1 Pt 2):1002-4.
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  204. Mikos AG, Bao Y, Cima LG, Ingber DE, Vacanti JP, Langer R. Preparation of poly(glycolic acid) bonded fiber structures for cell attachment and transplantation. J Biomed Mater Res. 1993 Feb; 27(2):183-9.
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  205. Sims JR, Karp S, Ingber DE. Altering the cellular mechanical force balance results in integrated changes in cell, cytoskeletal and nuclear shape. J Cell Sci. 1992 Dec; 103 ( Pt 4):1215-22.
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  206. Mooney D, Hansen L, Vacanti J, Langer R, Farmer S, Ingber D. Switching from differentiation to growth in hepatocytes: control by extracellular matrix. J Cell Physiol. 1992 Jun; 151(3):497-505.
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  207. Ingber DE. Extracellular matrix as a solid-state regulator in angiogenesis: identification of new targets for anti-cancer therapy. Semin Cancer Biol. 1992 Apr; 3(2):57-63.
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  208. Folkman J, Ingber D. Inhibition of angiogenesis. Semin Cancer Biol. 1992 Apr; 3(2):89-96.
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  209. Ingber D. Extracellular matrix and cell shape: potential control points for inhibition of angiogenesis. J Cell Biochem. 1991 Nov; 47(3):236-41.
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  210. Ingber D. Integrins as mechanochemical transducers. Curr Opin Cell Biol. 1991 Oct; 3(5):841-8.
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  211. Schwartz MA, Lechene C, Ingber DE. Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape. Proc Natl Acad Sci U S A. 1991 Sep 1; 88(17):7849-53.
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  212. Schwartz MA, Ingber DE, Lawrence M, Springer TA, Lechene C. Multiple integrins share the ability to induce elevation of intracellular pH. Exp Cell Res. 1991 Aug; 195(2):533-5.
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  213. Cima LG, Ingber DE, Vacanti JP, Langer R. Hepatocyte culture on biodegradable polymeric substrates. Biotechnol Bioeng. 1991 Jun 20; 38(2):145-58.
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  214. Cima LG, Vacanti JP, Vacanti C, Ingber D, Mooney D, Langer R. Tissue engineering by cell transplantation using degradable polymer substrates. J Biomech Eng. 1991 May; 113(2):143-51.
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  215. Ingber DE. Control of capillary growth and differentiation by extracellular matrix. Use of a tensegrity (tensional integrity) mechanism for signal processing. Chest. 1991 Mar; 99(3 Suppl):34S-40S.
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  216. Kusaka M, Sudo K, Fujita T, Marui S, Itoh F, Ingber D, Folkman J. Potent anti-angiogenic action of AGM-1470: comparison to the fumagillin parent. Biochem Biophys Res Commun. 1991 Feb 14; 174(3):1070-6.
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  217. Ingber D, Fujita T, Kishimoto S, Sudo K, Kanamaru T, Brem H, Folkman J. Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth. Nature. 1990 Dec 6; 348(6301):555-7.
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  218. Ingber DE. Fibronectin controls capillary endothelial cell growth by modulating cell shape. Proc Natl Acad Sci U S A. 1990 May; 87(9):3579-83.
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  219. Ingber DE, Prusty D, Frangioni JV, Cragoe EJ, Lechene C, Schwartz MA. Control of intracellular pH and growth by fibronectin in capillary endothelial cells. J Cell Biol. 1990 May; 110(5):1803-11.
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  220. Whalen GF, Ingber DE. Inhibition of tumor-cell attachment to extracellular matrix as a method for preventing tumor recurrence in a surgical wound. Ann Surg. 1989 Dec; 210(6):758-64.
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  221. Ingber DE, Folkman J. How does extracellular matrix control capillary morphogenesis? Cell. 1989 Sep 8; 58(5):803-5.
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  222. Hoffer FA, Taylor GA, Spevak M, Ingber D, Fenton T. Metabolism of tumor regression from angiogenesis inhibition: 31P magnetic resonance spectroscopy. Magn Reson Med. 1989 Aug; 11(2):202-8.
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  223. Ingber DE, Folkman J. Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in vitro: role of extracellular matrix. J Cell Biol. 1989 Jul; 109(1):317-30.
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  224. Folkman J, Watson K, Ingber D, Hanahan D. Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature. 1989 May 4; 339(6219):58-61.
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  225. Ingber D, Folkman J. Inhibition of angiogenesis through modulation of collagen metabolism. Lab Invest. 1988 Jul; 59(1):44-51.
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  226. Folkman J, Klagsbrun M, Sasse J, Wadzinski M, Ingber D, Vlodavsky I. A heparin-binding angiogenic protein--basic fibroblast growth factor--is stored within basement membrane. Am J Pathol. 1988 Feb; 130(2):393-400.
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  227. Folkman J, Ingber DE. Angiostatic steroids. Method of discovery and mechanism of action. Ann Surg. 1987 Sep; 206(3):374-83.
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  228. Ingber DE, Madri JA, Folkman J. Endothelial growth factors and extracellular matrix regulate DNA synthesis through modulation of cell and nuclear expansion. In Vitro Cell Dev Biol. 1987 May; 23(5):387-94.
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  229. Ingber DE, Folkman J. Regulation of endothelial growth factor action: solid state control by extracellular matrix. Prog Clin Biol Res. 1987; 249:273-82.
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  230. Wadzinski MG, Folkman J, Sasse J, Devey K, Ingber D, Klagsbrun M. Heparin-binding angiogenesis factors: detection by immunological methods. Clin Physiol Biochem. 1987; 5(3-4):200-9.
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  231. Ingber DE, Madri JA, Folkman J. A possible mechanism for inhibition of angiogenesis by angiostatic steroids: induction of capillary basement membrane dissolution. Endocrinology. 1986 Oct; 119(4):1768-75.
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  232. Ingber DE, Madri JA, Jamieson JD. Basement membrane as a spatial organizer of polarized epithelia. Exogenous basement membrane reorients pancreatic epithelial tumor cells in vitro. Am J Pathol. 1986 Jan; 122(1):129-39.
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  233. Ingber DE, Madri JA, Jamieson JD. Neoplastic disorganization of pancreatic epithelial cell-cell relations. Role of basement membrane. Am J Pathol. 1985 Nov; 121(2):248-60.
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  234. Ingber D, Brody R, Pearson C. Music therapy: tune-up for mind and body. Sci Dig. 1982 Jan; 90(1):78.
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  235. Ingber DE, Madri JA, Jamieson JD. Role of basal lamina in neoplastic disorganization of tissue architecture. Proc Natl Acad Sci U S A. 1981 Jun; 78(6):3901-5.
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  236. Jamieson JD, Ingber DE, Muresan V, Hull BE, Sarras MP, Maylié-Pfenninger MF, Iwanij V. Cell surface properties of normal, differentiating, and neoplastic pancreatic acinar cells. Cancer. 1981 Mar 15; 47(6 Suppl):1516-27.
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  237. Lazo JS, Ingber DE, Sartorelli AC. Enhancement of experimental lung metastases by cultured B16 melanoma cells treated with (+/-)-1,2-bis(3,5-dioxopiperazin-1-y)propane (ICRF-159). Cancer Res. 1978 Aug; 38(8):2263-70.
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