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Last Name
Institution

Nathaniel Moritz Alpert, PH.D.

TitleAssociate Professor of Radiology
InstitutionMassachusetts General Hospital
DepartmentRadiology
AddressMassachusetts General Hospital
White 427, Dept of Radiology
55 Fruit St
Boston MA 02114
Phone617/726-8358
Fax617/726-6165

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Alpert N, Dean Fang YH, Fakhri GE. Single-scan rest/stress imaging (18)F-labeled flow tracers. Med Phys. 2012 Nov; 39(11):6609-20.
    View in: PubMed
  2. Chun SY, Reese TG, Ouyang J, Guerin B, Catana C, Zhu X, Alpert NM, El Fakhri G. MRI-based nonrigid motion correction in simultaneous PET/MRI. J Nucl Med. 2012 Aug; 53(8):1284-91.
    View in: PubMed
  3. Fang YH, El Fakhri G, Becker JA, Alpert NM. Parametric imaging with Bayesian priors: a validation study with (11)C-Altropane PET. Neuroimage. 2012 May 15; 61(1):131-8.
    View in: PubMed
  4. Guérin B, Cho S, Chun SY, Zhu X, Alpert NM, El Fakhri G, Reese T, Catana C. Nonrigid PET motion compensation in the lower abdomen using simultaneous tagged-MRI and PET imaging. Med Phys. 2011 Jun; 38(6):3025-38.
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  5. Badgaiyan RD, Fischman AJ, Alpert NM. Dopamine release during human emotional processing. Neuroimage. 2009 Oct 1; 47(4):2041-5.
    View in: PubMed
  6. Alpert NM, Yuan F. A general method of Bayesian estimation for parametric imaging of the brain. Neuroimage. 2009 May 1; 45(4):1183-9.
    View in: PubMed
  7. Badgaiyan RD, Fischman AJ, Alpert NM. Explicit motor memory activates the striatal dopamine system. Neuroreport. 2008 Mar 5; 19(4):409-12.
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  8. Badgaiyan RD, Fischman AJ, Alpert NM. Striatal dopamine release in sequential learning. Neuroimage. 2007 Nov 15; 38(3):549-56.
    View in: PubMed
  9. Parodi K, Paganetti H, Cascio E, Flanz JB, Bonab AA, Alpert NM, Lohmann K, Bortfeld T. PET/CT imaging for treatment verification after proton therapy: a study with plastic phantoms and metallic implants. Med Phys. 2007 Feb; 34(2):419-35.
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  10. Rauch SL, Dougherty DD, Malone D, Rezai A, Friehs G, Fischman AJ, Alpert NM, Haber SN, Stypulkowski PH, Rise MT, Rasmussen SA, Greenberg BD. A functional neuroimaging investigation of deep brain stimulation in patients with obsessive-compulsive disorder. J Neurosurg. 2006 Apr; 104(4):558-65.
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  11. Dougherty DD, Bonab AA, Ottowitz WE, Livni E, Alpert NM, Rauch SL, Fava M, Fischman AJ. Decreased striatal D1 binding as measured using PET and [11C]SCH 23,390 in patients with major depression with anger attacks. Depress Anxiety. 2006; 23(3):175-7.
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  12. Tawakol A, Aziz K, Migrino R, Watkowska J, Zusman R, Alpert NM, Fischman AJ, Gewirtz H. Effects of sildenafil on myocardial blood flow in humans with ischemic heart disease. Coron Artery Dis. 2005 Nov; 16(7):443-9.
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  13. Alpert NM, Reilhac A, Chio TC, Selesnick I. Optimization of dynamic measurement of receptor kinetics by wavelet denoising. Neuroimage. 2006 Apr 1; 30(2):444-51.
    View in: PubMed
  14. O'Donnell JM, Zampino M, Alpert NM, Fasano MJ, Geenen DL, Lewandowski ED. Accelerated triacylglycerol turnover kinetics in hearts of diabetic rats include evidence for compartmented lipid storage. Am J Physiol Endocrinol Metab. 2006 Mar; 290(3):E448-55.
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  15. Tawakol A, Migrino RQ, Aziz KS, Waitkowska J, Holmvang G, Alpert NM, Muller JE, Fischman AJ, Gewirtz H. High-dose folic acid acutely improves coronary vasodilator function in patients with coronary artery disease. J Am Coll Cardiol. 2005 May 17; 45(10):1580-4.
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  16. Kosslyn SM, Thompson WL, Sukel KE, Alpert NM. Two types of image generation: evidence from PET. Cogn Affect Behav Neurosci. 2005 Mar; 5(1):41-53.
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  17. Dougherty DD, Rauch SL, Deckersbach T, Marci C, Loh R, Shin LM, Alpert NM, Fischman AJ, Fava M. Ventromedial prefrontal cortex and amygdala dysfunction during an anger induction positron emission tomography study in patients with major depressive disorder with anger attacks. Arch Gen Psychiatry. 2004 Aug; 61(8):795-804.
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  18. Shin LM, Orr SP, Carson MA, Rauch SL, Macklin ML, Lasko NB, Peters PM, Metzger LJ, Dougherty DD, Cannistraro PA, Alpert NM, Fischman AJ, Pitman RK. Regional cerebral blood flow in the amygdala and medial prefrontal cortex during traumatic imagery in male and female Vietnam veterans with PTSD. Arch Gen Psychiatry. 2004 Feb; 61(2):168-76.
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  19. Shin LM, Shin PS, Heckers S, Krangel TS, Macklin ML, Orr SP, Lasko N, Segal E, Makris N, Richert K, Levering J, Schacter DL, Alpert NM, Fischman AJ, Pitman RK, Rauch SL. Hippocampal function in posttraumatic stress disorder. Hippocampus. 2004; 14(3):292-300.
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  20. Badgaiyan RD, Schacter DL, Alpert NM. Priming of new associations: a PET study. Neuroreport. 2003 Dec 19; 14(18):2475-9.
    View in: PubMed
  21. Dougherty DD, Weiss AP, Cosgrove GR, Alpert NM, Cassem EH, Nierenberg AA, Price BH, Mayberg HS, Fischman AJ, Rauch SL. Cerebral metabolic correlates as potential predictors of response to anterior cingulotomy for treatment of major depression. J Neurosurg. 2003 Dec; 99(6):1010-7.
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  22. Badgaiyan RD, Fischman AJ, Alpert NM. Striatal dopamine release during unrewarded motor task in human volunteers. Neuroreport. 2003 Aug 6; 14(11):1421-4.
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  23. Wraga M, Thompson WL, Alpert NM, Kosslyn SM. Implicit transfer of motor strategies in mental rotation. Brain Cogn. 2003 Jul; 52(2):135-43.
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  24. Aquino SL, Asmuth JC, Alpert NM, Halpern EF, Fischman AJ. Improved radiologic staging of lung cancer with 2-[18F]-fluoro-2-deoxy-D-glucose-positron emission tomography and computed tomography registration. J Comput Assist Tomogr. 2003 Jul-Aug; 27(4):479-84.
    View in: PubMed
  25. Alpert NM, Badgaiyan RD, Livni E, Fischman AJ. A novel method for noninvasive detection of neuromodulatory changes in specific neurotransmitter systems. Neuroimage. 2003 Jul; 19(3):1049-60.
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  26. Caplan D, Waters G, Alpert N. Effects of age and speed of processing on rCBF correlates of syntactic processing in sentence comprehension. Hum Brain Mapp. 2003 Jun; 19(2):112-31.
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  27. Tawakol A, Sims K, MacRae C, Friedman JR, Alpert NM, Fischman AJ, Gewirtz H. Myocardial flow regulation in people with mitochondrial myopathy, encephalopathy, lactic acidosis, stroke-like episodes/myoclonic epilepsy and ragged red fibers and other mitochondrial syndromes. Coron Artery Dis. 2003 May; 14(3):197-205.
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  28. Waters G, Caplan D, Alpert N, Stanczak L. Individual differences in rCBF correlates of syntactic processing in sentence comprehension: effects of working memory and speed of processing. Neuroimage. 2003 May; 19(1):101-12.
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  29. Schellingerhout D, Lev MH, Bagga RJ, Rincon S, Berdichevsky D, Thangaraj V, Gonzalez RG, Alpert NM. Coregistration of head CT comparison studies: assessment of clinical utility. Acad Radiol. 2003 Mar; 10(3):242-8.
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  30. Weiss AP, Schacter DL, Goff DC, Rauch SL, Alpert NM, Fischman AJ, Heckers S. Impaired hippocampal recruitment during normal modulation of memory performance in schizophrenia. Biol Psychiatry. 2003 Jan 1; 53(1):48-55.
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  31. Rauch SL, Shin LM, Dougherty DD, Alpert NM, Fischman AJ, Jenike MA. Predictors of fluvoxamine response in contamination-related obsessive compulsive disorder: a PET symptom provocation study. Neuropsychopharmacology. 2002 Nov; 27(5):782-91.
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  32. Tawakol A, Forgione MA, Stuehlinger M, Alpert NM, Cooke JP, Loscalzo J, Fischman AJ, Creager MA, Gewirtz H. Homocysteine impairs coronary microvascular dilator function in humans. J Am Coll Cardiol. 2002 Sep 18; 40(6):1051-58.
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  33. Heckers S, Weiss AP, Alpert NM, Schacter DL. Hippocampal and brain stem activation during word retrieval after repeated and semantic encoding. Cereb Cortex. 2002 Sep; 12(9):900-7.
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  34. Badgaiyan RD, Schacter DL, Alpert NM. Retrieval of relational information: a role for the left inferior prefrontal cortex. Neuroimage. 2002 Sep; 17(1):393-400.
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  35. Fischman AJ, Hsu H, Carter EA, Yu YM, Tompkins RG, Guerrero JL, Young VR, Alpert NM. Regional measurement of canine skeletal muscle blood flow by positron emission tomography with H2(15)O. J Appl Physiol. 2002 Apr; 92(4):1709-16.
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  36. Alpert NM, Rabito CA, Correia DJ, Babich JW, Littman BH, Tompkins RG, Rubin NT, Rubin RH, Fischman AJ. Mapping of local renal blood flow with PET and H(2)(15)O. J Nucl Med. 2002 Apr; 43(4):470-5.
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  37. Kimura Y, Senda M, Alpert NM. Fast formation of statistically reliable FDG parametric images based on clustering and principal components. Phys Med Biol. 2002 Feb 7; 47(3):455-68.
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  38. Fischman AJ, Alpert NM, Rubin RH. Pharmacokinetic imaging: a noninvasive method for determining drug distribution and action. Clin Pharmacokinet. 2002; 41(8):581-602.
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  39. O'Donnell JM, Alpert NM, White LT, Lewandowski ED. Coupling of mitochondrial fatty acid uptake to oxidative flux in the intact heart. Biophys J. 2002 Jan; 82(1 Pt 1):11-8.
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  40. Rauch SL, Dougherty DD, Cosgrove GR, Cassem EH, Alpert NM, Price BH, Nierenberg AA, Mayberg HS, Baer L, Jenike MA, Fischman AJ. Cerebral metabolic correlates as potential predictors of response to anterior cingulotomy for obsessive compulsive disorder. Biol Psychiatry. 2001 Nov 1; 50(9):659-67.
    View in: PubMed
  41. Alpert NM, Berdichevsky D, Levin Z, Thangaraj V, Gonzalez G, Lev MH. Performance evaluation of an automated system for registration and postprocessing of CT scans. J Comput Assist Tomogr. 2001 Sep-Oct; 25(5):747-52.
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  42. Kosslyn SM, Thompson WL, Wraga M, Alpert NM. Imagining rotation by endogenous versus exogenous forces: distinct neural mechanisms. Neuroreport. 2001 Aug 8; 12(11):2519-25.
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  43. Thompson WL, Kosslyn SM, Sukel KE, Alpert NM. Mental imagery of high- and low-resolution gratings activates area 17. Neuroimage. 2001 Aug; 14(2):454-64.
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  44. Gordon CM, Dougherty DD, Fischman AJ, Emans SJ, Grace E, Lamm R, Alpert NM, Majzoub JA, Rauch SL. Neural substrates of anorexia nervosa: a behavioral challenge study with positron emission tomography. J Pediatr. 2001 Jul; 139(1):51-7.
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  45. Fischman AJ, Bonab AA, Babich JW, Livni E, Alpert NM, Meltzer PC, Madras BK. [(11)C, (127)I] Altropane: a highly selective ligand for PET imaging of dopamine transporter sites. Synapse. 2001 Mar 15; 39(4):332-42.
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  46. Badgaiyan RD, Schacter DL, Alpert NM. Priming within and across modalities: exploring the nature of rCBF increases and decreases. Neuroimage. 2001 Feb; 13(2):272-82.
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  47. Savage CR, Deckersbach T, Heckers S, Wagner AD, Schacter DL, Alpert NM, Fischman AJ, Rauch SL. Prefrontal regions supporting spontaneous and directed application of verbal learning strategies: evidence from PET. Brain. 2001 Jan; 124(Pt 1):219-31.
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  48. Tawakol A, Skopicki HA, Abraham SA, Alpert NM, Fischman AJ, Picard MH, Gewirtz H. Evidence of reduced resting blood flow in viable myocardial regions with chronic asynergy. J Am Coll Cardiol. 2000 Dec; 36(7):2146-53.
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  49. Heckers S, Curran T, Goff D, Rauch SL, Fischman AJ, Alpert NM, Schacter DL. Abnormalities in the thalamus and prefrontal cortex during episodic object recognition in schizophrenia. Biol Psychiatry. 2000 Oct 1; 48(7):651-7.
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  50. Kosslyn SM, Thompson WL, Costantini-Ferrando MF, Alpert NM, Spiegel D. Hypnotic visual illusion alters color processing in the brain. Am J Psychiatry. 2000 Aug; 157(8):1279-84.
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  51. Shin LM, Dougherty DD, Orr SP, Pitman RK, Lasko M, Macklin ML, Alpert NM, Fischman AJ, Rauch SL. Activation of anterior paralimbic structures during guilt-related script-driven imagery. Biol Psychiatry. 2000 Jul 1; 48(1):43-50.
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  52. Bonab AA, Fischman AJ, Alpert NM. Comparison of 4 methods for quantification of dopamine transporters by SPECT with [123I]IACFT. J Nucl Med. 2000 Jun; 41(6):1086-92.
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  53. Gordon CM, Dougherty DD, Rauch SL, Emans SJ, Grace E, Lamm R, Alpert NM, Majzoub JA, Fischman AJ. Neuroanatomy of human appetitive function: A positron emission tomography investigation. Int J Eat Disord. 2000 Mar; 27(2):163-71.
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  54. Caplan D, Alpert N, Waters G, Olivieri A. Activation of Broca's area by syntactic processing under conditions of concurrent articulation. Hum Brain Mapp. 2000 Feb; 9(2):65-71.
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  55. Heckers S, Goff D, Schacter DL, Savage CR, Fischman AJ, Alpert NM, Rauch SL. Functional imaging of memory retrieval in deficit vs nondeficit schizophrenia. Arch Gen Psychiatry. 1999 Dec; 56(12):1117-23.
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  56. Dougherty DD, Shin LM, Alpert NM, Pitman RK, Orr SP, Lasko M, Macklin ML, Fischman AJ, Rauch SL. Anger in healthy men: a PET study using script-driven imagery. Biol Psychiatry. 1999 Aug 15; 46(4):466-72.
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  57. Carter EA, Yu YM, Alpert NM, Bonab AA, Tompkins RG, Fischman AJ. Measurement of muscle protein synthesis by positron emission tomography with L-[methyl-11C]methionine: effects of transamination and transmethylation. J Trauma. 1999 Aug; 47(2):341-5.
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  58. Rauch SL, Shin LM, Dougherty DD, Alpert NM, Orr SP, Lasko M, Macklin ML, Fischman AJ, Pitman RK. Neural activation during sexual and competitive arousal in healthy men. Psychiatry Res. 1999 Jul 30; 91(1):1-10.
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  59. Schacter DL, Badgaiyan RD, Alpert NM. Visual word stem completion priming within and across modalities: a PET study. Neuroreport. 1999 Jul 13; 10(10):2061-5.
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  60. Badgaiyan RD, Schacter DL, Alpert NM. Auditory priming within and across modalities: evidence from positron emission tomography. J Cogn Neurosci. 1999 Jul; 11(4):337-48.
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  61. Holmvang G, Fry S, Skopicki HA, Abraham SA, Alpert NM, Fischman AJ, Picard MH, Gewirtz H. Relation between coronary "steal" and contractile function at rest in collateral-dependent myocardium of humans with ischemic heart disease. Circulation. 1999 May 18; 99(19):2510-6.
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  62. Zervos G, Zusman RM, Swindle LA, Alpert NM, Fischman AJ, Gewirtz H. Effects of nifedipine on myocardial blood flow and systolic function in humans with ischemic heart disease. Coron Artery Dis. 1999 May; 10(3):185-94.
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  63. Kimura Y, Hsu H, Toyama H, Senda M, Alpert NM. Improved signal-to-noise ratio in parametric images by cluster analysis. Neuroimage. 1999 May; 9(5):554-61.
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  64. Morris ED, Bonab AA, Alpert NM, Fischman AJ, Madras BK, Christian BT. Concentration of dopamine transporters: to Bmax or not to Bmax? Synapse. 1999 May; 32(2):136-40.
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  65. Kosslyn SM, Pascual-Leone A, Felician O, Camposano S, Keenan JP, Thompson WL, Ganis G, Sukel KE, Alpert NM. The role of area 17 in visual imagery: convergent evidence from PET and rTMS. Science. 1999 Apr 2; 284(5411):167-70.
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  66. Shin LM, McNally RJ, Kosslyn SM, Thompson WL, Rauch SL, Alpert NM, Metzger LJ, Lasko NB, Orr SP, Pitman RK. Regional cerebral blood flow during script-driven imagery in childhood sexual abuse-related PTSD: A PET investigation. Am J Psychiatry. 1999 Apr; 156(4):575-84.
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  67. Caplan D, Alpert N, Waters G. PET studies of syntactic processing with auditory sentence presentation. Neuroimage. 1999 Mar; 9(3):343-51.
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  68. Lewandowski ED, Alpert NM. Factors influencing isotope equilibrium rates affect 11C PET analysis. Circulation. 1999 Feb 23; 99(7):975-6.
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  69. Grachev ID, Berdichevsky D, Rauch SL, Heckers S, Kennedy DN, Caviness VS, Alpert NM. A method for assessing the accuracy of intersubject registration of the human brain using anatomic landmarks. Neuroimage. 1999 Feb; 9(2):250-68.
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  70. Fischman AJ, Yu YM, Livni E, Babich JW, Young VR, Alpert NM, Tompkins RG. Muscle protein synthesis by positron-emission tomography with L-[methyl-11C]methionine in adult humans. Proc Natl Acad Sci U S A. 1998 Oct 27; 95(22):12793-8.
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  71. O'Driscoll GA, Strakowski SM, Alpert NM, Matthysse SW, Rauch SL, Levy DL, Holzman PS. Differences in cerebral activation during smooth pursuit and saccadic eye movements using positron-emission tomography. Biol Psychiatry. 1998 Oct 15; 44(8):685-9.
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  72. Huggins GS, Pasternak RC, Alpert NM, Fischman AJ, Gewirtz H. Effects of short-term treatment of hyperlipidemia on coronary vasodilator function and myocardial perfusion in regions having substantial impairment of baseline dilator reverse. Circulation. 1998 Sep 29; 98(13):1291-6.
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  73. Fischman AJ, Babich JW, Bonab AA, Alpert NM, Vincent J, Callahan RJ, Correia JA, Rubin RH. Pharmacokinetics of [18F]trovafloxacin in healthy human subjects studied with positron emission tomography. Antimicrob Agents Chemother. 1998 Aug; 42(8):2048-54.
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  74. Heckers S, Rauch SL, Goff D, Savage CR, Schacter DL, Fischman AJ, Alpert NM. Impaired recruitment of the hippocampus during conscious recollection in schizophrenia. Nat Neurosci. 1998 Aug; 1(4):318-23.
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  75. Caplan D, Alpert N, Waters G. Effects of syntactic structure and propositional number on patterns of regional cerebral blood flow. J Cogn Neurosci. 1998 Jul; 10(4):541-52.
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  76. Fischman AJ, Bonab AA, Babich JW, Palmer EP, Alpert NM, Elmaleh DR, Callahan RJ, Barrow SA, Graham W, Meltzer PC, Hanson RN, Madras BK. Rapid detection of Parkinson's disease by SPECT with altropane: a selective ligand for dopamine transporters. Synapse. 1998 Jun; 29(2):128-41.
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  77. Kosslyn SM, DiGirolamo GJ, Thompson WL, Alpert NM. Mental rotation of objects versus hands: neural mechanisms revealed by positron emission tomography. Psychophysiology. 1998 Mar; 35(2):151-61.
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  78. O'Donnell JM, Doumen C, LaNoue KF, White LT, Yu X, Alpert NM, Lewandowski ED. Dehydrogenase regulation of metabolite oxidation and efflux from mitochondria in intact hearts. Am J Physiol. 1998 Feb; 274(2 Pt 2):H467-76.
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  79. Krebs HI, Brashers-Krug T, Rauch SL, Savage CR, Hogan N, Rubin RH, Fischman AJ, Alpert NM. Robot-aided functional imaging: application to a motor learning study. Hum Brain Mapp. 1998; 6(1):59-72.
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  80. Christian BT, Babich JW, Livni E, Alpert NM, Bonab AA, Munconi L, Polinski R, Rubin RH, Fischman AJ. Positron emission tomographic analysis of central dopamine D1 receptor binding in normal subjects treated with the atypical neuroleptic, SDZ MAR 327. Int J Mol Med. 1998 Jan; 1(1):243-7.
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  81. Skopicki HA, Abraham SA, Picard MH, Alpert NM, Fischman AJ, Gewirtz H. Effects of dobutamine at maximally tolerated dose on myocardial blood flow in humans with ischemic heart disease. Circulation. 1997 Nov 18; 96(10):3346-52.
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  82. Kosslyn SM, Thompson WL, Alpert NM. Neural systems shared by visual imagery and visual perception: a positron emission tomography study. Neuroimage. 1997 Nov; 6(4):320-34.
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  83. Fischman AJ, Alpert NM, Babich JW, Rubin RH. The role of positron emission tomography in pharmacokinetic analysis. Drug Metab Rev. 1997 Nov; 29(4):923-56.
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  84. Rauch SL, Savage CR, Alpert NM, Fischman AJ, Jenike MA. The functional neuroanatomy of anxiety: a study of three disorders using positron emission tomography and symptom provocation. Biol Psychiatry. 1997 Sep 15; 42(6):446-52.
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  85. Fischman AJ, Thornton AF, Frosch MP, Swearinger B, Gonzalez RG, Alpert NM. FDG hypermetabolism associated with inflammatory necrotic changes following radiation of meningioma. J Nucl Med. 1997 Jul; 38(7):1027-9.
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  86. Shin LM, McNally RJ, Kosslyn SM, Thompson WL, Rauch SL, Alpert NM, Metzger LJ, Lasko NB, Orr SP, Pitman RK. A positron emission tomographic study of symptom provocation in PTSD. Ann N Y Acad Sci. 1997 Jun 21; 821:521-3.
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  87. Yu X, Alpert NM, Lewandowski ED. Modeling enrichment kinetics from dynamic 13C-NMR spectra: theoretical analysis and practical considerations. Am J Physiol. 1997 Jun; 272(6 Pt 1):C2037-48.
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  88. Shin LM, Kosslyn SM, McNally RJ, Alpert NM, Thompson WL, Rauch SL, Macklin ML, Pitman RK. Visual imagery and perception in posttraumatic stress disorder. A positron emission tomographic investigation. Arch Gen Psychiatry. 1997 Mar; 54(3):233-41.
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  89. Fischman AJ, Babich JW, Alpert NM, Vincent J, Wilkinson RA, Callahan RJ, Correia JA, Rubin RH. Pharmacokinetics of 18F-labeled trovafloxacin in normal and Escherichia coli-infected rats and rabbits studied with positron emission tomography. Clin Microbiol Infect. 1997 Feb; 3(1):63-72.
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  90. Gewirtz H, Skopicki HA, Abraham SA, Castano H, Dinsmore RE, Alpert NM, Fischman AJ. Quantitative PET measurements of regional myocardial blood flow: observations in humans with ischemic heart disease. Cardiology. 1997 Jan-Feb; 88(1):62-70.
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  91. Carter EA, Tompkins RG, Hsu H, Christian B, Alpert NM, Weise S, Fischman AJ. Metabolic alterations in muscle of thermally injured rabbits, measured by positron emission tomography. Life Sci. 1997; 61(1):39-44.
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  92. Rauch SL, Savage CR, Alpert NM, Dougherty D, Kendrick A, Curran T, Brown HD, Manzo P, Fischman AJ, Jenike MA. Probing striatal function in obsessive-compulsive disorder: a PET study of implicit sequence learning. J Neuropsychiatry Clin Neurosci. 1997; 9(4):568-73.
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  93. Morris ED, Babich JW, Alpert NM, Bonab AA, Livni E, Weise S, Hsu H, Christian BT, Madras BK, Fischman AJ. Quantification of dopamine transporter density in monkeys by dynamic PET imaging of multiple injections of 11C-CFT. Synapse. 1996 Nov; 24(3):262-72.
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  94. Fischman AJ, Bonab AA, Babich JW, Alpert NM, Rauch SL, Elmaleh DR, Shoup TM, Williams SA, Rubin RH. Positron emission tomographic analysis of central 5-hydroxytryptamine2 receptor occupancy in healthy volunteers treated with the novel antipsychotic agent, ziprasidone. J Pharmacol Exp Ther. 1996 Nov; 279(2):939-47.
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  95. Christian BT, Livni E, Babich JW, Alpert NM, Dischino DD, Ruediger E, Salazar DE, Ford NF, Fischman AJ. Evaluation of cerebral pharmacokinetics of the novel antidepressant drug, BMS-181101, by positron emission tomography. J Pharmacol Exp Ther. 1996 Oct; 279(1):325-31.
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  96. Morris ED, Alpert NM, Fischman AJ. Comparison of two compartmental models for describing receptor ligand kinetics and receptor availability in multiple injection PET studies. J Cereb Blood Flow Metab. 1996 Sep; 16(5):841-53.
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  97. Rauch SL, Alpert NM, Savage CR. Functional anatomy of CCK-induced anxiety in normal volunteers. Am J Psychiatry. 1996 Sep; 153(9):1238-9.
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  98. Skopicki HA, Abraham SA, Weissman NJ, Mukerjee AK, Alpert NM, Fischman AJ, Picard MH, Gewirtz H. Factors influencing regional myocardial contractile response to inotropic stimulation. Analysis in humans with stable ischemic heart disease. Circulation. 1996 Aug 15; 94(4):643-50.
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  99. Kosslyn SM, Shin LM, Thompson WL, McNally RJ, Rauch SL, Pitman RK, Alpert NM. Neural effects of visualizing and perceiving aversive stimuli: a PET investigation. Neuroreport. 1996 Jul 8; 7(10):1569-76.
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  100. Hunter GJ, Hamberg LM, Alpert NM, Choi NC, Fischman AJ. Simplified measurement of deoxyglucose utilization rate. J Nucl Med. 1996 Jun; 37(6):950-5.
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  101. Yu X, White LT, Alpert NM, Lewandowski ED. Subcellular metabolite transport and carbon isotope kinetics in the intramyocardial glutamate pool. Biochemistry. 1996 May 28; 35(21):6963-8.
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  102. Rauch SL, van der Kolk BA, Fisler RE, Alpert NM, Orr SP, Savage CR, Fischman AJ, Jenike MA, Pitman RK. A symptom provocation study of posttraumatic stress disorder using positron emission tomography and script-driven imagery. Arch Gen Psychiatry. 1996 May; 53(5):380-7.
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  103. Schacter DL, Savage CR, Alpert NM, Rauch SL, Albert MS. The role of hippocampus and frontal cortex in age-related memory changes: a PET study. Neuroreport. 1996 Apr 26; 7(6):1165-9.
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  104. Hsu H, Yu YM, Babich JW, Burke JF, Livni E, Tompkins RG, Young VR, Alpert NM, Fischman AJ. Measurement of muscle protein synthesis by positron emission tomography with L-[methyl-11C]methionine. Proc Natl Acad Sci U S A. 1996 Mar 5; 93(5):1841-6.
    View in: PubMed
  105. Fischman AJ, Livni E, Babich JW, Alpert NM, Bonab A, Chodosh S, McGovern F, Kamitsuka P, Liu YY, Cleeland R, Prosser BL, Correia JA, Rubin RH. Pharmacokinetics of [18F]fleroxacin in patients with acute exacerbations of chronic bronchitis and complicated urinary tract infection studied by positron emission tomography. Antimicrob Agents Chemother. 1996 Mar; 40(3):659-64.
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  106. Stromswold K, Caplan D, Alpert N, Rauch S. Localization of syntactic comprehension by positron emission tomography. Brain Lang. 1996 Mar; 52(3):452-73.
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  107. Menard MT, Kosslyn SM, Thompson WL, Alpert NM, Rauch SL. Encoding words and pictures: a positron emission tomography study. Neuropsychologia. 1996 Mar; 34(3):185-94.
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  108. Gitelman DR, Alpert NM, Kosslyn S, Daffner K, Scinto L, Thompson W, Mesulam MM. Functional imaging of human right hemispheric activation for exploratory movements. Ann Neurol. 1996 Feb; 39(2):174-9.
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  109. Alpert NM, Berdichevsky D, Levin Z, Morris ED, Fischman AJ. Improved methods for image registration. Neuroimage. 1996 Feb; 3(1):10-8.
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  110. Schacter DL, Alpert NM, Savage CR, Rauch SL, Albert MS. Conscious recollection and the human hippocampal formation: evidence from positron emission tomography. Proc Natl Acad Sci U S A. 1996 Jan 9; 93(1):321-5.
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  111. Kosslyn SM, Thompson WL, Kim IJ, Alpert NM. Topographical representations of mental images in primary visual cortex. Nature. 1995 Nov 30; 378(6556):496-8.
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  112. Yu X, White LT, Doumen C, Damico LA, LaNoue KF, Alpert NM, Lewandowski ED. Kinetic analysis of dynamic 13C NMR spectra: metabolic flux, regulation, and compartmentation in hearts. Biophys J. 1995 Nov; 69(5):2090-102.
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  113. Hugdahl K, Berardi A, Thompson WL, Kosslyn SM, Macy R, Baker DP, Alpert NM, LeDoux JE. Brain mechanisms in human classical conditioning: a PET blood flow study. Neuroreport. 1995 Sep 11; 6(13):1723-8.
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  114. O'Driscoll GA, Alpert NM, Matthysse SW, Levy DL, Rauch SL, Holzman PS. Functional neuroanatomy of antisaccade eye movements investigated with positron emission tomography. Proc Natl Acad Sci U S A. 1995 Jan 31; 92(3):925-9.
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  115. Rauch SL, Savage CR, Alpert NM, Miguel EC, Baer L, Breiter HC, Fischman AJ, Manzo PA, Moretti C, Jenike MA. A positron emission tomographic study of simple phobic symptom provocation. Arch Gen Psychiatry. 1995 Jan; 52(1):20-8.
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  116. Kosslyn SM, Alpert NM, Thompson WL, Chabris CF, Rauch SL, Anderson AK. Identifying objects seen from different viewpoints. A PET investigation. Brain. 1994 Oct; 117 ( Pt 5):1055-71.
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  117. Hamberg LM, Hunter GJ, Alpert NM, Choi NC, Babich JW, Fischman AJ. The dose uptake ratio as an index of glucose metabolism: useful parameter or oversimplification? J Nucl Med. 1994 Aug; 35(8):1308-12.
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  118. Rubin RH, Livni E, Babich J, Alpert NM, Liu YY, Cleeland R, Prosser BL, Thom E, Fischman AJ. Tissue pharmacokinetics of fleroxacin in humans as determined by positron emission tomography. Int J Antimicrob Agents. 1994 Jul; 4 Suppl 2:S15-20.
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  119. Rauch SL, Savage CR, Alpert NM. Self-induced dysphoria and neural correlates. Am J Psychiatry. 1994 May; 151(5):784-5.
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  120. Meng J, Elmaleh DR, Jyawook S, Weiss S, Alpert NM, Babich JW, Tompkins RG, Fischman AJ. Synthesis of 2-[18F]fluoro-2-deoxy-L-glucose and positron emission tomography studies in monkeys. Nucl Med Biol. 1994 May; 21(4):633-40.
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  121. Gewirtz H, Fischman AJ, Abraham S, Gilson M, Strauss HW, Alpert NM. Positron emission tomographic measurements of absolute regional myocardial blood flow permits identification of nonviable myocardium in patients with chronic myocardial infarction. J Am Coll Cardiol. 1994 Mar 15; 23(4):851-9.
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  122. Elmaleh DR, Livni E, Alpert NM, Strauss HW, Buxton R, Fischman AJ. Myocardial extraction of 1-[11C] betamethylheptadecanoic acid. J Nucl Med. 1994 Mar; 35(3):496-503.
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  123. Bonini PA, Alpert N, Luzzana M, Rubin R. Guidelines for the identification and distribution of patient samples in the medical laboratory. J Automat Chem. 1994; 16(1):25-32.
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  124. Rauch SL, Jenike MA, Alpert NM, Baer L, Breiter HC, Savage CR, Fischman AJ. Regional cerebral blood flow measured during symptom provocation in obsessive-compulsive disorder using oxygen 15-labeled carbon dioxide and positron emission tomography. Arch Gen Psychiatry. 1994 Jan; 51(1):62-70.
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  125. Kosslyn SM, Daly PF, McPeek RM, Alpert NM, Kennedy DN, Caviness VS. Using locations to store shape: an indirect effect of a lesion. Cereb Cortex. 1993 Nov-Dec; 3(6):567-82.
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  126. Fischman AJ, Livni E, Babich J, Alpert NM, Liu YY, Thom E, Cleeland R, Prosser BL, Correia JA, Strauss HW, et al. Pharmacokinetics of [18F]fleroxacin in healthy human subjects studied by using positron emission tomography. Antimicrob Agents Chemother. 1993 Oct; 37(10):2144-52.
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  127. Goldberg MA, Lee MJ, Fischman AJ, Mueller PR, Alpert NM, Thrall JH. Fluorodeoxyglucose PET of abdominal and pelvic neoplasms: potential role in oncologic imaging. Radiographics. 1993 Sep; 13(5):1047-62.
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  128. Fischman AJ, Alpert NM, Livni E, Ray S, Sinclair I, Callahan RJ, Correia JA, Webb D, Strauss HW, Rubin RH. Pharmacokinetics of 18F-labeled fluconazole in healthy human subjects by positron emission tomography. Antimicrob Agents Chemother. 1993 Jun; 37(6):1270-7.
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  129. Pieri P, McKusick KA, Fischman AJ, Alpert N, Bougas C, Strauss HW. Characterization of the reinjection thallium image. J Nucl Med. 1993 Jun; 34(6):879-84.
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  130. Rubin RH, Livni E, Babich J, Alpert NM, Liu YY, Tham E, Prosser B, Cleeland R, Callahan RJ, Correia JA, et al. Pharmacokinetics of fleroxacin as studied by positron emission tomography and [18F]fleroxacin. Am J Med. 1993 Mar 22; 94(3A):31S-37S.
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  131. Livni E, Babich J, Alpert NM, Liu YY, Thom E, Cleeland R, Prosser BL, Correia JA, Strauss HW, Rubin RH, et al. Synthesis and biodistribution of 18F-labeled fleroxacin. Nucl Med Biol. 1993 Jan; 20(1):81-7.
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  132. Fischman AJ, Alpert NM. FDG-PET in oncology: there's more to it than looking at pictures. J Nucl Med. 1993 Jan; 34(1):6-11.
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  133. Fischman AJ, Livni E, Babich J, Alpert NM, Liu YY, Thom E, Cleeland R, Prosser BL, Callahan RJ, Correia JA, et al. Pharmacokinetics of 18F-labeled fleroxacin in rabbits with Escherichia coli infections, studied with positron emission tomography. Antimicrob Agents Chemother. 1992 Oct; 36(10):2286-92.
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  134. Livni E, Fischman AJ, Ray S, Sinclair I, Elmaleh DR, Alpert NM, Weiss S, Correia JA, Webb D, Dahl R, et al. Synthesis of 18F-labeled fluconazole and positron emission tomography studies in rabbits. Int J Rad Appl Instrum B. 1992 Feb; 19(2):191-9.
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  135. Senda M, Fishman AJ, Weise S, Alpert NM, Correia JA, Rubin RH, Strauss HW. Regional perfusion, oxygen metabolism, blood volume and immunoglobulin G accumulation at focal sites of infection in rabbits. Eur J Nucl Med. 1992; 19(3):166-72.
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  136. Fischman AJ, Alpert NM, Livni E, Ray S, Sinclair I, Elmaleh DR, Weiss S, Correia JA, Webb D, Liss R, et al. Pharmacokinetics of 18F-labeled fluconazole in rabbits with candidal infections studied with positron emission tomography. J Pharmacol Exp Ther. 1991 Dec; 259(3):1351-9.
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  137. Alpert N. Optimization of regional cerebral blood flow measurements with PET. J Nucl Med. 1991 Oct; 32(10):1934-6.
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  138. Alpert NM, Barker WC, Gelman A, Weise S, Senda M, Correia JA. The precision of positron emission tomography: theory and measurement. J Cereb Blood Flow Metab. 1991 Mar; 11(2):A26-30.
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  139. Alpert NM, Bradshaw JF, Kennedy D, Correia JA. The principal axes transformation--a method for image registration. J Nucl Med. 1990 Oct; 31(10):1717-22.
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  140. Ishibashi M, Yasuda T, Rocco TP, Alpert N, Moore RH, Strauss HW. Evaluation of left ventricular diastolic function using an ambulatory radionuclide monitor: relationship to left ventricular systolic performance. Am Heart J. 1990 Jul; 120(1):96-103.
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  141. Flamm SD, Taki J, Moore R, Lewis SF, Keech F, Maltais F, Ahmad M, Callahan R, Dragotakes S, Alpert N, et al. Redistribution of regional and organ blood volume and effect on cardiac function in relation to upright exercise intensity in healthy human subjects. Circulation. 1990 May; 81(5):1550-9.
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  142. Senda M, Alpert NM, Mackay BC, Buxton RB, Correia JA, Weise SB, Ackerman RH, Dorer D, Buonanno FS. Evaluation of the 11CO2 positron emission tomographic method for measuring brain pH. II. Quantitative pH mapping in patients with ischemic cerebrovascular diseases. J Cereb Blood Flow Metab. 1989 Dec; 9(6):859-73.
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  143. Correia JA, Alpert NM. Properties of digital images in radiology. J Digit Imaging. 1988 Nov; 1(1):18-23.
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  144. Senda M, Buxton RB, Alpert NM, Correia JA, Mackay BC, Weise SB, Ackerman RH. The 15O steady-state method: correction for variation in arterial concentration. J Cereb Blood Flow Metab. 1988 Oct; 8(5):681-90.
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  145. Alpert NM, Buxton RB, Correia JA, Katz PM, Ackerman RH. Measurement of end-capillary PO2 with positron emission tomography. J Cereb Blood Flow Metab. 1988 Jun; 8(3):403-10.
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  146. Tamaki N, Alpert NM, Rabito CA, Barlai-Kovach M, Correia JA, Strauss HW. The effect of captopril on renal blood flow in renal artery stenosis assessed by positron tomography with rubidium-82. Hypertension. 1988 Mar; 11(3):217-22.
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  147. Molnar JA, Alpert NM, Wagner DA, Miyatani S, Burke JF, Young VR. Synthesis and degradation of collagens in skin of healthy and protein-malnourished rats in vivo, studied by 18O2 labelling. Biochem J. 1988 Feb 15; 250(1):71-6.
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  148. Buxton RB, Alpert NM, Babikian V, Weise S, Correia JA, Ackerman RH. Evaluation of the 11CO2 positron emission tomographic method for measuring brain pH. I. pH changes measured in states of altered PCO2. J Cereb Blood Flow Metab. 1987 Dec; 7(6):709-19.
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  149. Ohsuzu F, Yasuda T, Gold HK, Leinbach RC, Rosenthal SV, Alpert NM, Boucher CA, McKusick KA, Strauss HW. Evolutionary changes in left and right ventricular function in acute myocardial infarction. Ann Nucl Med. 1987 Sep; 1(1):7-14.
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  150. Molnar JA, Alpert NM, Burke JF, Young VR. Relative and absolute changes in soluble and insoluble collagen pool size in skin during normal growth and with dietary protein restriction in rats. Growth. 1987; 51(1):132-45.
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  151. Molnar JA, Alpert N, Burke JF, Young VR. Synthesis and degradation rates of collagens in vivo in whole skin of rats, studied with 1802 labelling. Biochem J. 1986 Dec 1; 240(2):431-5.
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  152. Tamaki N, Rabito CA, Alpert NM, Yasuda T, Correia JA, Barlai-Kovach M, Kanke M, Dragotakes SC, Strauss HW. Serial analysis of renal blood flow by positron tomography with rubidium-82. Am J Physiol. 1986 Nov; 251(5 Pt 2):H1024-30.
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  153. Livni E, Spellman JP, Correia JA, Alpert NM, Brownell GL, Strauss HW, Elmaleh DR. [11C]MPTP: a potential tracer for Parkinson's disease research in laboratory animals. J Nucl Med. 1986 Oct; 27(10):1600-3.
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  154. Correia JA, Alpert NM, Buxton RB, Ackerman RH. Analysis of some errors in the measurement of oxygen extraction and oxygen consumption by the equilibrium inhalation method. J Cereb Blood Flow Metab. 1985 Dec; 5(4):591-9.
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  155. Correia JA, Alpert NM. Positron emission tomography in cardiology. Radiol Clin North Am. 1985 Dec; 23(4):783-93.
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  156. Buxton RB, Wechsler LR, Alpert NM, Ackerman RH, Elmaleh DR, Correia JA. Measurement of brain pH using 11CO2 and positron emission tomography. J Cereb Blood Flow Metab. 1984 Mar; 4(1):8-16.
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  157. Alpert NM, Eriksson L, Chang JY, Bergstrom M, Litton JE, Correia JA, Bohm C, Ackerman RH, Taveras JM. Strategy for the measurement of regional cerebral blood flow using short-lived tracers and emission tomography. J Cereb Blood Flow Metab. 1984 Mar; 4(1):28-34.
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  158. Ackerman RH, Alpert NM, Correia JA, Finklestein S, Davis SM, Kelley RE, Donnan GA, D'Alton JG, Taveras JM. Positron imaging in ischemic stroke disease. Ann Neurol. 1984; 15 Suppl:S126-30.
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  159. Kearfott KJ, Elmaleh DR, Goodman M, Correia JA, Alpert NM, Ackerman RH, Brownell GL, Strauss WH. Comparison of 2- and 3-18F-fluoro-deoxy-D-glucose for studies of tissue metabolism. Int J Nucl Med Biol. 1984; 11(1):15-22.
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  160. Brownell GL, Kearfott KJ, Kairento AL, Elmaleh DR, Alpert NM, Correia JA, Wechsler L, Ackerman RH. Quantitation of regional cerebral glucose metabolism. J Comput Assist Tomogr. 1983 Oct; 7(5):919-24.
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  161. Davis SM, Ackerman RH, Correia JA, Alpert NM, Chang J, Buonanno F, Kelley RE, Rosner B, Taveras JM. Cerebral blood flow and cerebrovascular CO2 reactivity in stroke-age normal controls. Neurology. 1983 Apr; 33(4):391-9.
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  162. Goldhaber SZ, Newell JB, Alpert NM, Andrews E, Pohost GM, Ingwall JS. Effects of ischemic-like insult on myocardial thallium-201 accumulation. Circulation. 1983 Apr; 67(4):778-86.
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  163. Goldhaber SZ, Newell JB, Ingwall JS, Pohost GM, Alpert NM, Fossel ET. Effects of reduced coronary flow on thallium-201 accumulation and release in an in vitro rat heart preparation. Am J Cardiol. 1983 Mar 1; 51(5):891-6.
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  164. Correia JA, Bucelewicz WH, Strauss HW, Alpert NM, Brownell GL, Taveras JM, Ferrari V. Transportation of short-lived positron emitters from a medical cyclotron to a remote imaging suite. Med Phys. 1983 Mar-Apr; 10(2):228-31.
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  165. Moore RH, Alpert NM, Strauss HW. A variable angle slant-hole collimator. J Nucl Med. 1983 Jan; 24(1):61-5.
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  166. Finklestein S, Alpert NM, Ackerman RH, Correia JA, Buonanno FS, Chang J, Brownell GL, Taveras JM. Positron brain imaging--normal patterns and asymmetries. Brain Cogn. 1982 Jul; 1(3):286-93.
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  167. Alpert NM, Chesler DA, Correia JA, Ackerman RH, Chang JY, Finklestein S, Davis SM, Brownell GL, Taveras JM. Estimation of the local statistical noise in emission computed tomography. IEEE Trans Med Imaging. 1982; 1(2):142-6.
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  168. Ackerman RH, Correia JA, Alpert NM, Baron JC, Gouliamos A, Grotta JC, Brownell GL, Taveras JM. Positron imaging in ischemic stroke disease using compounds labeled with oxygen 15. Initial results of clinicophysiologic correlations. Arch Neurol. 1981 Sep; 38(9):537-43.
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  169. Goodman MM, Elmaleh DR, Kearfott KJ, Ackerman RH, Hoop B, Brownell GL, Alpert NM, Strauss HW. F-18-labeled 3-deoxy-3-fluoro-D-glucose for the study of regional metabolism in the brain and heart. J Nucl Med. 1981 Feb; 22(2):138-44.
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  170. Brownell GL, Ackerman RH, Strauss HW, Elmaleh DR, Cochavi S, Alpert N, Correia JA, Kearfott KJ, Taveras J. Preliminary imaging results with 18F-2-fluoro-2-deoxy-D-glucose. J Comput Assist Tomogr. 1980 Aug; 4(4):473-7.
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  171. Finklestein S, Alpert NM, Ackerman RH, Buonanno FS, Correia JA, Chang J, Kulas S, Brownell GL, Taveras JM. Positron imaging of the normal brain--regional patterns of cerebral blood flow and metabolism. Trans Am Neurol Assoc. 1980; 105:8-10.
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  172. Pohost GM, Alpert NM, Ingwall JS, Strauss HW. Thallium redistribution: mechanisms and clinical utility. Semin Nucl Med. 1980 Jan; 10(1):70-93.
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  173. Ackerman RH, Subramanyam R, Correia JA, Alpert NM, Taveras JM. Positron imaging of cerebral blood flow during continuous inhalation of C15O2. Stroke. 1980 Jan-Feb; 11(1):45-9.
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  174. Konstam MA, Strauss HW, Alpert NM, Miller SW, Murphy RX, Greene RE, McKusick KA. Noninvasive estimation of pulmonary arterial pressure by analysis of pulmonary blood-flow distribution. J Nucl Med. 1979 Sep; 20(9):923-7.
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  175. Subramanyam R, Alpert NM, Hoop B, Brownell GL, Taveras JM. A model for regional cerebral oxygen distribution during continuous inhalation of 15O2, C15O, and C15O2. J Nucl Med. 1978 Jan; 19(1):48-53.
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  176. Alpert NM, McKusick KA, Correia JA, Shea W, Brownell GL, Potsaid MS. Initial assessment of a simple functional image of ventilation. J Nucl Med. 1976 Feb; 17(02):88-92.
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  177. Alpert NM, Burnham CA, Deveau LA, Correll JE, Chesler DA, Pizer SM, Brownell GL. NUMEDICS: a system for on-line data processing in nuclear medicine. J Nucl Med. 1975 May; 16(5):386-92.
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  178. Alpert NM, McKusick KA, Pohost GM, Dinsmore RE, Potsaid MS. Noninvasive nuclear kinecardiography. J Nucl Med. 1974 Dec; 15(12):1182-4.
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