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Karl G. Helmer, Ph.D.

TitleInstructor in Radiology
InstitutionMassachusetts General Hospital
DepartmentRadiology
AddressMassachusetts General Hospital
Radiology, Rm. 2301
149 13th Street
Charlestown MA 02129

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Keator DB, Helmer K, Steffener J, Turner JA, Van Erp TG, Gadde S, Ashish N, Burns GA, Nichols BN. Towards structured sharing of raw and derived neuroimaging data across existing resources. Neuroimage. 2013 Nov 15; 82:647-61.
    View in: PubMed
  2. Shenton ME, Hamoda HM, Schneiderman JS, Bouix S, Pasternak O, Rathi Y, Vu MA, Purohit MP, Helmer K, Koerte I, Lin AP, Westin CF, Kikinis R, Kubicki M, Stern RA, Zafonte R. A review of magnetic resonance imaging and diffusion tensor imaging findings in mild traumatic brain injury. Brain Imaging Behav. 2012 Jun; 6(2):137-92.
    View in: PubMed
  3. Poline JB, Breeze JL, Ghosh S, Gorgolewski K, Halchenko YO, Hanke M, Haselgrove C, Helmer KG, Keator DB, Marcus DS, Poldrack RA, Schwartz Y, Ashburner J, Kennedy DN. Data sharing in neuroimaging research. Front Neuroinform. 2012; 6:9.
    View in: PubMed
  4. Cohen-Adad J, Polimeni JR, Helmer KG, Benner T, McNab JA, Wald LL, Rosen BR, Mainero C. T2* mapping and B0 orientation-dependence at 7 T reveal cyto- and myeloarchitecture organization of the human cortex. Neuroimage. 2012 Apr 2; 60(2):1006-14.
    View in: PubMed
  5. Magnotta VA, Matsui JT, Liu D, Johnson HJ, Long JD, Bolster BD, Mueller BA, Lim K, Mori S, Helmer KG, Turner JA, Reading S, Lowe MJ, Aylward E, Flashman LA, Bonett G, Paulsen JS. MultiCenter Reliability of Diffusion Tensor Imaging. Brain Connect. 2012; 2(6):345-55.
    View in: PubMed
  6. Helmer KG, Ambite JL, Ames J, Ananthakrishnan R, Burns G, Chervenak AL, Foster I, Liming L, Keator D, Macciardi F, Madduri R, Navarro JP, Potkin S, Rosen B, Ruffins S, Schuler R, Turner JA, Toga A, Williams C, Kesselman C. Enabling collaborative research using the Biomedical Informatics Research Network (BIRN). J Am Med Inform Assoc. 2011 Jul-Aug; 18(4):416-22.
    View in: PubMed
  7. Augustinack JC, Helmer K, Huber KE, Kakunoori S, Zöllei L, Fischl B. Direct visualization of the perforant pathway in the human brain with ex vivo diffusion tensor imaging. Front Hum Neurosci. 2010; 4:42.
    View in: PubMed
  8. Paskavitz JF, Sweet LH, Wellen J, Helmer KG, Rao SM, Cohen RA. Recruitment and stabilization of brain activation within a working memory task; an FMRI study. Brain Imaging Behav. 2010 Mar; 4(1):5-21.
    View in: PubMed
  9. Schaechter JD, Fricker ZP, Perdue KL, Helmer KG, Vangel MG, Greve DN, Makris N. Microstructural status of ipsilesional and contralesional corticospinal tract correlates with motor skill in chronic stroke patients. Hum Brain Mapp. 2009 Nov; 30(11):3461-74.
    View in: PubMed
  10. Salat DH, Greve DN, Pacheco JL, Quinn BT, Helmer KG, Buckner RL, Fischl B. Regional white matter volume differences in nondemented aging and Alzheimer's disease. Neuroimage. 2009 Feb 15; 44(4):1247-58.
    View in: PubMed
  11. Henning EC, Azuma C, Sotak CH, Helmer KG. Multispectral quantification of tissue types in a RIF-1 tumor model with histological validation. Part I. Magn Reson Med. 2007 Mar; 57(3):501-12.
    View in: PubMed
  12. Henning EC, Azuma C, Sotak CH, Helmer KG. Multispectral tissue characterization in a RIF-1 tumor model: monitoring the ADC and T2 responses to single-dose radiotherapy. Part II. Magn Reson Med. 2007 Mar; 57(3):513-9.
    View in: PubMed
  13. Helmer KG, Nair G, Cannella M, Grigg P. Water movement in tendon in response to a repeated static tensile load using one-dimensional magnetic resonance imaging. J Biomech Eng. 2006 Oct; 128(5):733-41.
    View in: PubMed
  14. Wellen J, Helmer KG, Grigg P, Sotak CH. Spatial characterization of T1 and T2 relaxation times and the water apparent diffusion coefficient in rabbit Achilles tendon subjected to tensile loading. Magn Reson Med. 2005 Mar; 53(3):535-44.
    View in: PubMed
  15. Helmer KG, Wellen J, Grigg P, Sotak CH. Measurement of the spatial redistribution of water in rabbit Achilles tendon in response to static tensile loading. J Biomech Eng. 2004 Oct; 126(5):651-6.
    View in: PubMed
  16. Wellen J, Helmer KG, Grigg P, Sotak CH. Application of porous-media theory to the investigation of water ADC changes in rabbit Achilles tendon caused by tensile loading. J Magn Reson. 2004 Sep; 170(1):49-55.
    View in: PubMed
  17. Helmer KG, Meiler MR, Sotak CH, Petruccelli JD. Comparison of the return-to-the-origin probability and the apparent diffusion coefficient of water as indicators of necrosis in RIF-1 tumors. Magn Reson Med. 2003 Mar; 49(3):468-78.
    View in: PubMed
  18. Silva MD, Omae T, Helmer KG, Li F, Fisher M, Sotak CH. Separating changes in the intra- and extracellular water apparent diffusion coefficient following focal cerebral ischemia in the rat brain. Magn Reson Med. 2002 Nov; 48(5):826-37.
    View in: PubMed
  19. Silva MD, Helmer KG, Lee JH, Han SS, Springer CS, Sotak CH. Deconvolution of compartmental water diffusion coefficients in yeast-cell suspensions using combined T(1) and diffusion measurements. J Magn Reson. 2002 May; 156(1):52-63.
    View in: PubMed
  20. Li F, Liu KF, Silva MD, Meng X, Gerriets T, Helmer KG, Fenstermacher JD, Sotak CH, Fisher M. Acute postischemic renormalization of the apparent diffusion coefficient of water is not associated with reversal of astrocytic swelling and neuronal shrinkage in rats. AJNR Am J Neuroradiol. 2002 Feb; 23(2):180-8.
    View in: PubMed
  21. Carano RA, Li F, Irie K, Helmer KG, Silva MD, Fisher M, Sotak CH. Multispectral analysis of the temporal evolution of cerebral ischemia in the rat brain. J Magn Reson Imaging. 2000 Dec; 12(6):842-58.
    View in: PubMed
  22. Li F, Silva MD, Liu KF, Helmer KG, Omae T, Fenstermacher JD, Sotak CH, Fisher M. Secondary decline in apparent diffusion coefficient and neurological outcomes after a short period of focal brain ischemia in rats. Ann Neurol. 2000 Aug; 48(2):236-44.
    View in: PubMed
  23. Han S, Gemmell SJ, Helmer KG, Grigg P, Wellen JW, Hoffman AH, Sotak CH. Changes in ADC caused by tensile loading of rabbit achilles tendon: evidence for water transport. J Magn Reson. 2000 Jun; 144(2):217-27.
    View in: PubMed
  24. Carano RA, Takano K, Helmer KG, Tatlisumak T, Irie K, Petruccelli JD, Fisher M, Sotak CH. Determination of focal ischemic lesion volume in the rat brain using multispectral analysis. J Magn Reson Imaging. 1998 Nov-Dec; 8(6):1266-78.
    View in: PubMed
  25. Hürlimann MD, Helmer KG, Sotak CH. Dephasing of Hahn echo in rocks by diffusion in susceptibility-induced field inhomogeneities. Magn Reson Imaging. 1998 Jun-Jul; 16(5-6):535-9.
    View in: PubMed
  26. Helmer KG, Han S, Sotak CH. On the correlation between the water diffusion coefficient and oxygen tension in RIF-1 tumors. NMR Biomed. 1998 May; 11(3):120-30.
    View in: PubMed
  27. Takano K, Latour LL, Formato JE, Carano RA, Helmer KG, Hasegawa Y, Sotak CH, Fisher M. The role of spreading depression in focal ischemia evaluated by diffusion mapping. Ann Neurol. 1996 Mar; 39(3):308-18.
    View in: PubMed
  28. Helmer KG, Dardzinski BJ, Sotak CH. The application of porous-media theory to the investigation of time-dependent diffusion in in vivo systems. NMR Biomed. 1995 Nov-Dec; 8(7-8):297-306.
    View in: PubMed
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