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Wei Wei, PH.D.

TitleResearch Fellow in Medicine (EXT)
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
Hem/Onc GRJ 9
55 Fruit St
Boston MA 02114

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Sun WY, Song Y, Hu SS, Wang QT, Wu HX, Chen JY, Wei W. Depletion of ß-arrestin2 in hepatic stellate cells reduces cell proliferation via ERK pathway. J Cell Biochem. 2013 May; 114(5):1153-62.
    View in: PubMed
  2. Zhao S, Ma CM, Liu CX, Wei W, Sun Y, Yan H, Wu YL. Autophagy inhibition enhances isobavachalcone-induced cell death in multiple myeloma cells. Int J Mol Med. 2012 Oct; 30(4):939-44.
    View in: PubMed
  3. Gao FH, Liu F, Wei W, Liu LB, Xu MH, Guo ZY, Li W, Jiang B, Wu YL. Oridonin induces apoptosis and senescence by increasing hydrogen peroxide and glutathione depletion in colorectal cancer cells. Int J Mol Med. 2012 Apr; 29(4):649-55.
    View in: PubMed
  4. Sun WY, Wang L, Liu H, Li X, Wei W. A standardized extract from Paeonia lactiflora and Astragalus membranaceus attenuates liver fibrosis induced by porcine serum in rats. Int J Mol Med. 2012 Mar; 29(3):491-8.
    View in: PubMed
  5. Chang Y, Zhang L, Wang C, Jia XY, Wei W. Paeoniflorin inhibits function of synoviocytes pretreated by rIL-1a and regulates EP4 receptor expression. J Ethnopharmacol. 2011 Oct 11; 137(3):1275-82.
    View in: PubMed
  6. Li X, Kang N, Zhang X, Dong X, Wei W, Cui L, Ba D, He W. Generation of human regulatory gammadelta T cells by TCRgammadelta stimulation in the presence of TGF-beta and their involvement in the pathogenesis of systemic lupus erythematosus. J Immunol. 2011 Jun 15; 186(12):6693-700.
    View in: PubMed
  7. Wei W, Yang Z, Tang CH, Liu L. Targeted deletion of GSNOR in hepatocytes of mice causes nitrosative inactivation of O6-alkylguanine-DNA alkyltransferase and increased sensitivity to genotoxic diethylnitrosamine. Carcinogenesis. 2011 Jul; 32(7):973-7.
    View in: PubMed
  8. Wei W, Luo X, Zheng L, Yu M, Jiang N, Xu XY, Yang ZR. Isolation of a wild Morchella spp. strain and the effects of its extract on ethanol-induced gastric mucosal lesions in rats. Z Naturforsch C. 2011 Jan-Feb; 66(1-2):55-62.
    View in: PubMed
  9. Wei W, Barron PD, Rheinwald JG. Modulation of TGF-ß-inducible hypermotility by EGF and other factors in human prostate epithelial cells and keratinocytes. In Vitro Cell Dev Biol Anim. 2010 Dec; 46(10):841-55.
    View in: PubMed
  10. Ou ZJ, Wei W, Huang DD, Luo W, Luo D, Wang ZP, Zhang X, Ou JS. L-arginine restores endothelial nitric oxide synthase-coupled activity and attenuates monocrotaline-induced pulmonary artery hypertension in rats. Am J Physiol Endocrinol Metab. 2010 Jun; 298(6):E1131-9.
    View in: PubMed
  11. Liu Q, Wang G, Zhou G, Tan Y, Wang X, Wei W, Liu L, Xue W, Feng W, Cai L. Angiotensin II-induced p53-dependent cardiac apoptotic cell death: its prevention by metallothionein. Toxicol Lett. 2009 Dec 15; 191(2-3):314-20.
    View in: PubMed
  12. Liang HJ, Wei W, Kang XN, Guo K, Cao J, Su JJ, Yang C, Ou C, Li Y, Liu YK. [Differentially expressed proteins in the precancerous stage of rat hepatocarcinogenesis induced by diethylnitrosamine]. Zhonghua Gan Zang Bing Za Zhi. 2009 Sep; 17(9):669-74.
    View in: PubMed
  13. Lopez G, Liu J, Ren W, Wei W, Wang S, Lahat G, Zhu QS, Bornmann WG, McConkey DJ, Pollock RE, Lev DC. Combining PCI-24781, a novel histone deacetylase inhibitor, with chemotherapy for the treatment of soft tissue sarcoma. Clin Cancer Res. 2009 May 15; 15(10):3472-83.
    View in: PubMed
  14. Zhang CE, Wei W, Liu YH, Peng JH, Tian Q, Liu GP, Zhang Y, Wang JZ. Hyperhomocysteinemia increases beta-amyloid by enhancing expression of gamma-secretase and phosphorylation of amyloid precursor protein in rat brain. Am J Pathol. 2009 Apr; 174(4):1481-91.
    View in: PubMed
  15. Guan L, Han B, Li Z, Hua F, Huang F, Wei W, Yang Y, Xu C. Sodium selenite induces apoptosis by ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction in human acute promyelocytic leukemia NB4 cells. Apoptosis. 2009 Feb; 14(2):218-25.
    View in: PubMed
  16. Li W, Wei W, Zhu S, Zhu J, Shi Y, Lin T, Hao E, Hayek A, Deng H, Ding S. Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors. Cell Stem Cell. 2009 Jan 9; 4(1):16-9.
    View in: PubMed
  17. Mukhtar MM, Li S, Li W, Wan T, Mu Y, Wei W, Kang L, Rasool ST, Xiao Y, Zhu Y, Wu J. Single-chain intracellular antibodies inhibit influenza virus replication by disrupting interaction of proteins involved in viral replication and transcription. Int J Biochem Cell Biol. 2009 Mar; 41(3):554-60.
    View in: PubMed
  18. Zhu HQ, Cheng XW, Xiao LL, Jiang ZK, Zhou Q, Gui SY, Wei W, Wang Y. Melatonin prevents oxidized low-density lipoprotein-induced increase of myosin light chain kinase activation and expression in HUVEC through ERK/MAPK signal transduction. J Pineal Res. 2008 Oct; 45(3):328-34.
    View in: PubMed
  19. Liu YH, Wei W, Yin J, Liu GP, Wang Q, Cao FY, Wang JZ. Proteasome inhibition increases tau accumulation independent of phosphorylation. Neurobiol Aging. 2009 Dec; 30(12):1949-61.
    View in: PubMed
  20. Jia YT, Wei W, Ma B, Xu Y, Liu WJ, Wang Y, Lv KY, Tang HT, Wei D, Xia ZF. Activation of p38 MAPK by reactive oxygen species is essential in a rat model of stress-induced gastric mucosal injury. J Immunol. 2007 Dec 1; 179(11):7808-19.
    View in: PubMed
  21. Menconi M, Fareed M, O'Neal P, Poylin V, Wei W, Hasselgren PO. Role of glucocorticoids in the molecular regulation of muscle wasting. Crit Care Med. 2007 Sep; 35(9 Suppl):S602-8.
    View in: PubMed
  22. Zhan LB, Zhong JH, Lu XG, Sui H, Wei W. [Protective effects of nourishing spleen yin recipe on endoplasmic reticulum stress-induced neuronal cell damage and its mechanism]. Zhong Xi Yi Jie He Xue Bao. 2007 Jul; 5(4):445-50.
    View in: PubMed
  23. Jia L, Cao J, Wei W, Wang S, Zuo Y, Zhang J. CD147 depletion down-regulates matrix metalloproteinase-11, vascular endothelial growth factor-A expression and the lymphatic metastasis potential of murine hepatocarcinoma Hca-F cells. Int J Biochem Cell Biol. 2007; 39(11):2135-42.
    View in: PubMed
  24. Jia L, Wang S, Cao J, Zhou H, Wei W, Zhang J. siRNA targeted against matrix metalloproteinase 11 inhibits the metastatic capability of murine hepatocarcinoma cell Hca-F to lymph nodes. Int J Biochem Cell Biol. 2007; 39(11):2049-62.
    View in: PubMed
  25. Jia YT, Ma B, Wei W, Xu Y, Wang Y, Tang HT, Xia ZF. Sustained activation of nuclear factor-kappaB by reactive oxygen species is involved in the pathogenesis of stress-induced gastric damage in rats. Crit Care Med. 2007 Jun; 35(6):1582-91.
    View in: PubMed
  26. Zou F, Liu Y, Liu L, Wu K, Wei W, Zhu Y, Wu J. Retinoic acid activates human inducible nitric oxide synthase gene through binding of RARalpha/RXRalpha heterodimer to a novel retinoic acid response element in the promoter. Biochem Biophys Res Commun. 2007 Apr 6; 355(2):494-500.
    View in: PubMed
  27. Wang G, Qi X, Wei W, Englander EW, Greeley GH. Characterization of the 5'-regulatory regions of the rat and human apelin genes and regulation of breast apelin by USF. FASEB J. 2006 Dec; 20(14):2639-41.
    View in: PubMed
  28. Wei W, Yang H, Menconi M, Cao P, Chamberlain CE, Hasselgren PO. Treatment of cultured myotubes with the proteasome inhibitor beta-lactone increases the expression of the transcription factor C/EBPbeta. Am J Physiol Cell Physiol. 2007 Jan; 292(1):C216-26.
    View in: PubMed
  29. Yang H, Wei W, Menconi M, Hasselgren PO. Dexamethasone-induced protein degradation in cultured myotubes is p300/HAT dependent. Am J Physiol Regul Integr Comp Physiol. 2007 Jan; 292(1):R337-4.
    View in: PubMed
  30. Evenson A, Mitchell J, Wei W, Poylin V, Parangi S, Hasselgren PO. The gene expression and activity of calpains and the muscle wasting-associated ubiquitin ligases, atrogin-1 and MuRF1, are not altered in patients with primary hyperparathyroidism. Int J Mol Med. 2006 Sep; 18(3):471-5.
    View in: PubMed
  31. Wei W, Yang H, Cao P, Menconi M, Chamberlain C, Petkova V, Hasselgren PO. Degradation of C/EBPbeta in cultured myotubes is calpain-dependent. J Cell Physiol. 2006 Aug; 208(2):386-98.
    View in: PubMed
  32. Xu DX, Wang JP, Sun MF, Chen YH, Wei W. Lipopolysaccharide downregulates the expressions of intestinal pregnane X receptor and cytochrome P450 3a11. Eur J Pharmacol. 2006 Apr 24; 536(1-2):162-70.
    View in: PubMed
  33. Fareed MU, Evenson AR, Wei W, Menconi M, Poylin V, Petkova V, Pignol B, Hasselgren PO. Treatment of rats with calpain inhibitors prevents sepsis-induced muscle proteolysis independent of atrogin-1/MAFbx and MuRF1 expression. Am J Physiol Regul Integr Comp Physiol. 2006 Jun; 290(6):R1589-97.
    View in: PubMed
  34. Wei W, Qi X, Reed J, Ceci J, Wang HQ, Wang G, Englander EW, Greeley GH. Effect of chronic hyperghrelinemia on ingestive action of ghrelin. Am J Physiol Regul Integr Comp Physiol. 2006 Mar; 290(3):R803-8.
    View in: PubMed
  35. Yang H, Mammen J, Wei W, Menconi M, Evenson A, Fareed M, Petkova V, Hasselgren PO. Expression and activity of C/EBPbeta and delta are upregulated by dexamethasone in skeletal muscle. J Cell Physiol. 2005 Jul; 204(1):219-26.
    View in: PubMed
  36. Yang H, Menconi MJ, Wei W, Petkova V, Hasselgren PO. Dexamethasone upregulates the expression of the nuclear cofactor p300 and its interaction with C/EBPbeta in cultured myotubes. J Cell Biochem. 2005 Apr 1; 94(5):1058-67.
    View in: PubMed
  37. Hasselgren PO, Menconi MJ, Fareed MU, Yang H, Wei W, Evenson A. Novel aspects on the regulation of muscle wasting in sepsis. Int J Biochem Cell Biol. 2005 Oct; 37(10):2156-68.
    View in: PubMed
  38. Chen ZW, Huang Y, Yang Q, Li X, Wei W, He GW. Urocortin-induced relaxation in the human internal mammary artery. Cardiovasc Res. 2005 Mar 1; 65(4):913-20.
    View in: PubMed
  39. Wei W, Wang G, Qi X, Englander EW, Greeley GH. Characterization and regulation of the rat and human ghrelin promoters. Endocrinology. 2005 Mar; 146(3):1611-25.
    View in: PubMed
  40. Wei W, Fareed MU, Evenson A, Menconi MJ, Yang H, Petkova V, Hasselgren PO. Sepsis stimulates calpain activity in skeletal muscle by decreasing calpastatin activity but does not activate caspase-3. Am J Physiol Regul Integr Comp Physiol. 2005 Mar; 288(3):R580-90.
    View in: PubMed
  41. Menconi MJ, Wei W, Yang H, Wray CJ, Hasselgren PO. Treatment of cultured myotubes with the calcium ionophore A23187 increases proteasome activity via a CaMK II-caspase-calpain-dependent mechanism. Surgery. 2004 Aug; 136(2):135-42.
    View in: PubMed
  42. Goll DE, Thompson VF, Li H, Wei W, Cong J. The calpain system. Physiol Rev. 2003 Jul; 83(3):731-801.
    View in: PubMed
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