Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution

Robert Conrad Fuhlbrigge, Ph.D., M.D.

TitleAssociate Professor of Pediatrics
InstitutionChildren's Hospital Boston
DepartmentPediatrics
AddressBrigham and Womens Hospital
Eugene Braunwald Research Ctr, Room 501
221 Longwood Ave
Boston MA 02115
Phone617/525-8501
Fax617/264-5123
Other Positions
TitleAssociate Professor of Dermatology
InstitutionBrigham and Women's Hospital
DepartmentDermatology


 Mentoring 
 current student opportunities
Available: 08/30/13, Expires: 08/31/14

Participate in ongoing research regarding the regulation of leukocyte migration to skin and their participation in inflammatory, infectious and malignant disorders of skin.

 completed student projects

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Vander Lugt B, Tubo NJ, Nizza ST, Boes M, Malissen B, Fuhlbrigge RC, Kupper TS, Campbell JJ. CCR7 Plays No Appreciable Role in Trafficking of Central Memory CD4 T Cells to Lymph Nodes. J Immunol. 2013 Sep 15; 191(6):3119-27.
    View in: PubMed
  2. Kentsis A, Shulman A, Ahmed S, Brennan E, Monuteaux MC, Lee YH, Lipsett S, Paulo JA, Dedeoglu F, Fuhlbrigge R, Bachur R, Bradwin G, Arditi M, Sundel RP, Newburger JW, Steen H, Kim S. Urine proteomics for discovery of improved diagnostic markers of Kawasaki disease. EMBO Mol Med. 2013 Feb; 5(2):210-20.
    View in: PubMed
  3. Ercan A, Barnes MG, Hazen M, Tory H, Henderson L, Dedeoglu F, Fuhlbrigge RC, Grom A, Holm IA, Kellogg M, Kim S, Adamczyk B, Rudd PM, Son MB, Sundel RP, Foell D, Glass DN, Thompson SD, Nigrovic PA. Multiple juvenile idiopathic arthritis subtypes demonstrate proinflammatory IgG glycosylation. Arthritis Rheum. 2012 Sep; 64(9):3025-33.
    View in: PubMed
  4. Chang DK, Sui J, Geng S, Muvaffak A, Bai M, Fuhlbrigge RC, Lo A, Yammanuru A, Hubbard L, Sheehan J, Campbell JJ, Zhu Q, Kupper TS, Marasco WA. Humanization of an Anti-CCR4 Antibody That Kills Cutaneous T-Cell Lymphoma Cells and Abrogates Suppression by T-Regulatory Cells. Mol Cancer Ther. 2012 Nov; 11(11):2451-61.
    View in: PubMed
  5. Li SC, Torok KS, Pope E, Dedeoglu F, Hong S, Jacobe HT, Rabinovich CE, Laxer RM, Higgins GC, Ferguson PJ, Lasky A, Baszis K, Becker M, Campillo S, Cartwright V, Cidon M, Inman CJ, Jerath R, O'Neil KM, Vora S, Zeft A, Wallace CA, Ilowite NT, Fuhlbrigge RC. Development of consensus treatment plans for juvenile localized scleroderma: a roadmap toward comparative effectiveness studies in juvenile localized scleroderma. Arthritis Care Res (Hoboken). 2012 Aug; 64(8):1175-85.
    View in: PubMed
  6. Purwar R, Schlapbach C, Xiao S, Kang HS, Elyaman W, Jiang X, Jetten AM, Khoury SJ, Fuhlbrigge RC, Kuchroo VK, Clark RA, Kupper TS. Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells. Nat Med. 2012 Jul 8.
    View in: PubMed
  7. Wang JX, Bair AM, King SL, Shnayder R, Huang YF, Shieh CC, Soberman RJ, Fuhlbrigge RC, Nigrovic PA. Ly6G ligation blocks recruitment of neutrophils via a ß2-integrin-dependent mechanism. Blood. 2012 Aug 16; 120(7):1489-98.
    View in: PubMed
  8. Jiang X, Clark RA, Liu L, Wagers AJ, Fuhlbrigge RC, Kupper TS. Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity. Nature. 2012 Mar 8; 483(7388):227-31.
    View in: PubMed
  9. Tian T, Dubin K, Jin Q, Qureshi A, King SL, Liu L, Jiang X, Murphy GF, Kupper TS, Fuhlbrigge RC. Disruption of TNF-a/TNFR1 function in resident skin cells impairs host immune response against cutaneous vaccinia virus infection. J Invest Dermatol. 2012 May; 132(5):1425-34.
    View in: PubMed
  10. Peiser M, Tralau T, Heidler J, Api AM, Arts JH, Basketter DA, English J, Diepgen TL, Fuhlbrigge RC, Gaspari AA, Johansen JD, Karlberg AT, Kimber I, Lepoittevin JP, Liebsch M, Maibach HI, Martin SF, Merk HF, Platzek T, Rustemeyer T, Schnuch A, Vandebriel RJ, White IR, Luch A. Allergic contact dermatitis: epidemiology, molecular mechanisms, in vitro methods and regulatory aspects. Current knowledge assembled at an international workshop at BfR, Germany. Cell Mol Life Sci. 2012 Mar; 69(5):763-81.
    View in: PubMed
  11. Merzaban JS, Burdick MM, Gadhoum SZ, Dagia NM, Chu JT, Fuhlbrigge RC, Sackstein R. Analysis of glycoprotein E-selectin ligands on human and mouse marrow cells enriched for hematopoietic stem/progenitor cells. Blood. 2011 Aug 18; 118(7):1774-83.
    View in: PubMed
  12. Vander Lugt B, Beck ZT, Fuhlbrigge RC, Hacohen N, Campbell JJ, Boes M. TGF-ß suppresses ß-catenin-dependent tolerogenic activation program in dendritic cells. PLoS One. 2011; 6(5):e20099.
    View in: PubMed
  13. Fuhlbrigge RC, Chaiban R. The immune system, the skin, and childhood rheumatic disease. Curr Rheumatol Rep. 2011 Apr; 13(2):103-9.
    View in: PubMed
  14. Koduru S, Kumar L, Massaad MJ, Ramesh N, Le Bras S, Ozcan E, Oyoshi MK, Kaku M, Fujiwara Y, Kremer L, King S, Fuhlbrigge R, Rodig S, Sage P, Carman C, Alcaide P, Luscinskas FW, Geha RS. Cdc42 interacting protein 4 (CIP4) is essential for integrin-dependent T-cell trafficking. Proc Natl Acad Sci U S A. 2010 Sep 14; 107(37):16252-6.
    View in: PubMed
  15. Yamanaka K, Fuhlbrigge RC, Mizutani H, Kupper TS. Restoration of peripheral blood T cell repertoire complexity during remission in advanced cutaneous T cell lymphoma. Arch Dermatol Res. 2010 Aug; 302(6):453-9.
    View in: PubMed
  16. Ozen S, Fuhlbrigge RC. Update in paediatric vasculitis. Best Pract Res Clin Rheumatol. 2009 Oct; 23(5):679-88.
    View in: PubMed
  17. Clark RA, Fuhlbrigge RC. Immunology and skin disease 2009: frontiers in cutaneous immunology. J Invest Dermatol. 2009 Aug; 129(8):1849-51.
    View in: PubMed
  18. Kim S, El-Hallak M, Dedeoglu F, Zurakowski D, Fuhlbrigge RC, Sundel RP. Complete and sustained remission of juvenile dermatomyositis resulting from aggressive treatment. Arthritis Rheum. 2009 Jun; 60(6):1825-30.
    View in: PubMed
  19. Bianchi T, Pincus LB, Wurbel MA, Rich BE, Kupper TS, Fuhlbrigge RC, Boes M. Maintenance of peripheral tolerance through controlled tissue homing of antigen-specific T cells in K14-mOVA mice. J Immunol. 2009 Apr 15; 182(8):4665-74.
    View in: PubMed
  20. Sackstein R, Fuhlbrigge R. Western blot analysis of adhesive interactions under fluid shear conditions: the blot rolling assay. Methods Mol Biol. 2009; 536:343-54.
    View in: PubMed
  21. Tian T, Liu L, Freyschmidt EJ, Murphy GF, Kupper TS, Fuhlbrigge RC. Overexpression of IL-1alpha in skin differentially modulates the immune response to scarification with vaccinia virus. J Invest Dermatol. 2009 Jan; 129(1):70-8.
    View in: PubMed
  22. Ota S, Cron RQ, Schanberg LE, O'Neil K, Mellins ED, Fuhlbrigge RC, Feldman BM. Research priorities in pediatric rheumatology: The Childhood Arthritis and Rheumatology Research Alliance (CARRA) consensus. Pediatr Rheumatol Online J. 2008; 6:5.
    View in: PubMed
  23. Schatton T, Murphy GF, Frank NY, Yamaura K, Waaga-Gasser AM, Gasser M, Zhan Q, Jordan S, Duncan LM, Weishaupt C, Fuhlbrigge RC, Kupper TS, Sayegh MH, Frank MH. Identification of cells initiating human melanomas. Nature. 2008 Jan 17; 451(7176):345-9.
    View in: PubMed
  24. Yamanaka K, Dimitroff CJ, Fuhlbrigge RC, Kakeda M, Kurokawa I, Mizutani H, Kupper TS. Vitamins A and D are potent inhibitors of cutaneous lymphocyte-associated antigen expression. J Allergy Clin Immunol. 2008 Jan; 121(1):148-157.e3.
    View in: PubMed
  25. Clark RA, Fuhlbrigge RC. Meeting report of immunology and skin disease: new perspectives. J Invest Dermatol. 2007 Aug; 127(8):1838-41.
    View in: PubMed
  26. Weishaupt C, Munoz KN, Buzney E, Kupper TS, Fuhlbrigge RC. T-cell distribution and adhesion receptor expression in metastatic melanoma. Clin Cancer Res. 2007 May 1; 13(9):2549-56.
    View in: PubMed
  27. Fuhlbrigge RC, Weishaupt C. Adhesion molecules in cutaneous immunity. Semin Immunopathol. 2007 Apr; 29(1):45-57.
    View in: PubMed
  28. El-Hallak M, Binstadt BA, Leichtner AM, Bennett CM, Neufeld EJ, Fuhlbrigge RC, Zurakowski D, Sundel RP. Clinical effects and safety of rituximab for treatment of refractory pediatric autoimmune diseases. J Pediatr. 2007 Apr; 150(4):376-82.
    View in: PubMed
  29. Alcaide P, King SL, Dimitroff CJ, Lim YC, Fuhlbrigge RC, Luscinskas FW. The 130-kDa glycoform of CD43 functions as an E-selectin ligand for activated Th1 cells in vitro and in delayed-type hypersensitivity reactions in vivo. J Invest Dermatol. 2007 Aug; 127(8):1964-72.
    View in: PubMed
  30. Weishaupt, C, KN Munoz, E Buzney, TS Kupper, and RC Fuhlbrigge. Dysregulation of vascular adhesion molecules in metastatic melanoma. Clinical Cancer Research. 2007; 13(9):2549-56.
  31. El-Hallak M, Binstadt BA, Leichtner AM, Bennett CM, Neufeld EJ, Fuhlbrigge RC, Zurakowski D, Sundel RP. Clinical effects and safety of rituximab for treatment of refractory pediatric autoimmune diseases. J Pediatrics. 2007; 150:376-82.
  32. Tian T, L Liu, E-J Freyschmidt, G Murphy, TS Kupper and RC Fuhlbrigge. Modulation of Immune Response to Vaccinia Virus Scarification in K14/IL-1á Transgenic Mice. Journal of Virology. 2007; Submitted.
  33. Hirahara K, Liu L, Clark RA, Yamanaka K, Fuhlbrigge RC, Kupper TS. The majority of human peripheral blood CD4+CD25highFoxp3+ regulatory T cells bear functional skin-homing receptors. J Immunol. 2006 Oct 1; 177(7):4488-94.
    View in: PubMed
  34. Liu L, Fuhlbrigge RC, Karibian K, Tian T, Kupper TS. Dynamic programming of CD8+ T cell trafficking after live viral immunization. Immunity. 2006 Sep; 25(3):511-20.
    View in: PubMed
  35. Goldbach-Mansky R, Dailey NJ, Canna SW, Gelabert A, Jones J, Rubin BI, Kim HJ, Brewer C, Zalewski C, Wiggs E, Hill S, Turner ML, Karp BI, Aksentijevich I, Pucino F, Penzak SR, Haverkamp MH, Stein L, Adams BS, Moore TL, Fuhlbrigge RC, Shaham B, Jarvis JN, O'Neil K, Vehe RK, Beitz LO, Gardner G, Hannan WP, Warren RW, Horn W, Cole JL, Paul SM, Hawkins PN, Pham TH, Snyder C, Wesley RA, Hoffmann SC, Holland SM, Butman JA, Kastner DL. Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition. N Engl J Med. 2006 Aug 10; 355(6):581-92.
    View in: PubMed
  36. Goldbach-Mansky, R., N. Dailey, S. Canna, A. Gelabert, J. Jones, B. Rubin, J. Kim, C. Brewer, C. Zalewski, E. Wiggs, S. Hill, M. Turner, B. Karp, I. Aksentijevich, F. Pucino, S. Penzak , M. Haverkamp, L. Stein, B.S. Adams, T.L. Moore, R. Fuhlbrigge, B. Shaham, J. Jarvis, R. Vehe, L. Beitz, G. Gardner, W. Hannan, R. Warren, W. Horn, J.L. Cole, S. Paul, P. Hawkins, T. Hang Pham, C. Snyder, J. Butman, S. Hoffman, S.M. Holland, and D.L. Kastner. Neonatal Onset Multisystem Inflammatory Disease––A Disorder of Interleukin 1 Signaling Responsive to Anakinra. New England Journal of Medicine. 2006; 355(6):581-92.
  37. Hirahara, K., L. Liu, R.A. Clark, K. Yamanaka, R.C. Fuhlbrigge, and T.S. Kupper. The Majority of Human Peripheral Blood CD4+CD25highFoxp3+ Regulatory T Cells Bear Functional Skin-Homing Receptors. Journal of Immunology. 2006; 177:4488-4494.
  38. Fuhlbrigge, R.C., S.L. King, R. Sackstein, and T.S. Kupper. CD43 is a Ligand for E-selectin on Human Skin Homing T Cells. ePub Nov 2005. Blood. 2006; 107:1421-6.
  39. Liu L., RC Fuhlbrigge, K Karibian, T Tian, TS Kupper. 2006. . Dynamic programming of CD8+ T cell trafficking after live viral immunization. Immunity 25(3):511-20. 2006; 25(3):511-20.
  40. Sackstein R, Fuhlbrigge R. The blot rolling assay: a method for identifying adhesion molecules mediating binding under shear conditions. Methods Mol Biol. 2006; 341:217-26.
    View in: PubMed
  41. Fuhlbrigge RC, King SL, Sackstein R, Kupper TS. CD43 is a ligand for E-selectin on CLA+ human T cells. Blood. 2006 Feb 15; 107(4):1421-6.
    View in: PubMed
  42. Gallego MD, de la Fuente MA, Anton IM, Snapper S, Fuhlbrigge R, Geha RS. WIP and WASP play complementary roles in T cell homing and chemotaxis to SDF-1alpha. Int Immunol. 2006 Feb; 18(2):221-32.
    View in: PubMed
  43. Binstadt BA, Levine JC, Nigrovic PA, Gauvreau K, Dedeoglu F, Fuhlbrigge RC, Weindling SN, Newburger JW, Sundel RP. Coronary artery dilation among patients presenting with systemic-onset juvenile idiopathic arthritis. Pediatrics. 2005 Jul; 116(1):e89-93.
    View in: PubMed
  44. Liu L, Xu Z, Fuhlbrigge RC, Peña-Cruz V, Lieberman J, Kupper TS. Vaccinia virus induces strong immunoregulatory cytokine production in healthy human epidermal keratinocytes: a novel strategy for immune evasion. J Virol. 2005 Jun; 79(12):7363-70.
    View in: PubMed
  45. Kupper TS, Fuhlbrigge RC. Immune surveillance in the skin: mechanisms and clinical consequences. Nat Rev Immunol. 2004 Mar; 4(3):211-22.
    View in: PubMed
  46. Chong BF, Murphy JE, Kupper TS, Fuhlbrigge RC. E-selectin, thymus- and activation-regulated chemokine/CCL17, and intercellular adhesion molecule-1 are constitutively coexpressed in dermal microvessels: a foundation for a cutaneous immunosurveillance system. J Immunol. 2004 Feb 1; 172(3):1575-81.
    View in: PubMed
  47. Chong, B.F., J.E. Murphy, T.S. Kupper, R.C. Fuhlbrigge . E-selectin, TARC/CCL17 and ICAM-1 are constitutively co-expressed in dermal microvessels: a foundation for a cutaneous immunosurveillance mechanism. Journal of Immunology. 2004; 172:1575-1581.
  48. Binstadt BA, Caldas AM, Turvey SE, Stone KD, Weinstein HJ, Jackson J, Fuhlbrigge RC, Sundel RP. Rituximab therapy for multisystem autoimmune diseases in pediatric patients. J Pediatr. 2003 Nov; 143(5):598-604.
    View in: PubMed
  49. Nigrovic PA, Fuhlbrigge RC, Sundel RP. Raynaud's phenomenon in children: a retrospective review of 123 patients. Pediatrics. 2003 Apr; 111(4 Pt 1):715-21.
    View in: PubMed
  50. Binstadt, B.A., A.M.C. Caldas, S.E., Turvey, H.J. Weinstein, J. M. Jackson, R.C. Fuhlbrigge and R.P. Sundel . Rituximab Therapy for Mulstisystem Autoimmune Disease in Pediatric Patients. Journal of Pediatrics. 2003; 143(5):598-604.
  51. Ferenczi K, Fuhlbrigge RC, Pinkus J, Pinkus GS, Kupper TS. Increased CCR4 expression in cutaneous T cell lymphoma. J Invest Dermatol. 2002 Dec; 119(6):1405-10.
    View in: PubMed
  52. Fisler RE, Liang MG, Fuhlbrigge RC, Yalcindag A, Sundel RP. Aggressive management of juvenile dermatomyositis results in improved outcome and decreased incidence of calcinosis. J Am Acad Dermatol. 2002 Oct; 47(4):505-11.
    View in: PubMed
  53. Fuhlbrigge RC, King SL, Dimitroff CJ, Kupper TS, Sackstein R. Direct real-time observation of E- and P-selectin-mediated rolling on cutaneous lymphocyte-associated antigen immobilized on Western blots. J Immunol. 2002 Jun 1; 168(11):5645-51.
    View in: PubMed
  54. Pendl GG, Robert C, Steinert M, Thanos R, Eytner R, Borges E, Wild MK, Lowe JB, Fuhlbrigge RC, Kupper TS, Vestweber D, Grabbe S. Immature mouse dendritic cells enter inflamed tissue, a process that requires E- and P-selectin, but not P-selectin glycoprotein ligand 1. Blood. 2002 Feb 1; 99(3):946-56.
    View in: PubMed
  55. Ferenczi K, Fuhlbrigge RC, Pinkus J, Pinkus GS, Kupper TS . Increased CCR4 Expression in Cutaneous T Cell Lymphom. A. J Invest Dermatol. 2002; 119(6):1405-10.
  56. Fuhlbrigge, R.C., S.L. King, C.J. Dimitroff and R. Sackstein. . Direct, Real-time Observation of E- and P- Selectin Mediated Rolling on Cutaneous Lymphocyte-Associated Antigen Immobilized on Western Blots. Journal of Immunology. 2002; 168:5645-5651.
  57. Armerding D, Fuhlbrigge RC, Kieffer JD, Kupper TS. Tonsillar B cells do not express PSGL-1, but a significant fraction displays the cutaneous lymphocyte antigen and exhibits effective E- and P-selectin ligand activity. Int Arch Allergy Immunol. 2001 Sep; 126(1):78-90.
    View in: PubMed
  58. Kieffer JD, Fuhlbrigge RC, Armerding D, Robert C, Ferenczi K, Camphausen RT, Kupper TS. Neutrophils, monocytes, and dendritic cells express the same specialized form of PSGL-1 as do skin-homing memory T cells: cutaneous lymphocyte antigen. Biochem Biophys Res Commun. 2001 Jul 20; 285(3):577-87.
    View in: PubMed
  59. Dimitroff CJ, Lee JY, Rafii S, Fuhlbrigge RC, Sackstein R. CD44 is a major E-selectin ligand on human hematopoietic progenitor cells. J Cell Biol. 2001 Jun 11; 153(6):1277-86.
    View in: PubMed
  60. Dimitroff, C.J., J.Y. Lee, S. Rafii, R.C. Fuhlbrigge and R. Sackstein . CD44 is a major E-Selectin Ligand on Human Hemotpoetic Progenitor Cells. Journal of Cell Biology. 2001; 153(6):1277-86.
  61. Artlett, C.M., F.W. Miller, L.G. Rider, et al. for the Childhood Myositis Heterogeneity Collaborative Study Group. . Persistent maternally-derived peripheral michrochimerism is associated with the juvenile idiopathic inflammatory myopathies. Rheumatology. 2001; 40:1279-84.
  62. Dimitroff CJ, Lee JY, Fuhlbrigge RC, Sackstein R. A distinct glycoform of CD44 is an L-selectin ligand on human hematopoietic cells. Proc Natl Acad Sci U S A. 2000 Dec 5; 97(25):13841-6.
    View in: PubMed
  63. Eberhard BA, Sundel RP, Newburger JW, Baker A, Fuhlbrigge RC, Burns JC, Gellis SE. Psoriatic eruption in Kawasaki disease. J Pediatr. 2000 Oct; 137(4):578-80.
    View in: PubMed
  64. Robert, C. Fuhlbrigge, M.D., Ph.D. Apparatus and Methods for Identifying Ligands. 2000.
  65. Carcamo AS, Fuhlbrigge RC, Hong R, Gullans SR, Kupper TS. Comparative analysis of the global transcriptional profile of human skin-homing memory T lymphocytes vs. non-skin homing memory and naive T lymphocytes J Invest Dermatol. 2000 Aug; 115(2):332.
    View in: PubMed
  66. Carcamo, A.S., R.C. Fuhlbrigge, R. Hong, S.R. Gullans and T.S.; Kupper. . Comparative analysis of the global transcriptional profile of human skin-homing memory T lymphocytes vs. non-skin homing memory and naive T lymphocytes. Journal of Investigative Dermatology. 2000; 115(2):332.
  67. Dimitroff, C.J., J. Lee, R.C. Fuhlbrigge and R. Sackstein. . A Distinct Glycoform of CD44 is an L-selectin Ligand on Human Hematopoietic Progenitor Cells. Proceedings of the National Academy of Sciences (USA). 2000; 97(25):13,814 - 13,13846.
  68. Fuhlbrigge, R.C. and T.S. Kupper. . Molecular mechanisms of allergic skin responses. Allergic Skin Diseases. Editors: Leung and Greaves. 2000; 29-51.
  69. Robert C, Fuhlbrigge RC, Kieffer JD, Ayehunie S, Hynes RO, Cheng G, Grabbe S, von Andrian UH, Kupper TS. Interaction of dendritic cells with skin endothelium: A new perspective on immunosurveillance. J Exp Med. 1999 Feb 15; 189(4):627-36.
    View in: PubMed
  70. Alon R, Chen S, Fuhlbrigge R, Puri KD, Springer TA. The kinetics and shear threshold of transient and rolling interactions of L-selectin with its ligand on leukocytes. Proc Natl Acad Sci U S A. 1998 Sep 29; 95(20):11631-6.
    View in: PubMed
  71. Clark RA, Fuhlbrigge RC, Springer TA. L-Selectin ligands that are O-glycoprotease resistant and distinct from MECA-79 antigen are sufficient for tethering and rolling of lymphocytes on human high endothelial venules. J Cell Biol. 1998 Feb 9; 140(3):721-31.
    View in: PubMed
  72. Clark, R.A., R.C. Fuhlbrigge and T.A. Springer. . L-selectin ligands that are O-glycoprotease-resistant and distinct from MECA-79 antigen are sufficient for tethering and rolling of lymphocytes on human high endothelial venules. Journal of Cell Biology. 1998; 140 (3):721-731.
  73. Fuhlbrigge, RC, D. Samler and R.P. Sundel. . Aggressive Management of Juvenile Dermatomyositis (JDMS) Prevents Calcinosis. Proceedings of Park City IV: Pediatric Rheumatology Into The Next Century. 1998.
  74. Fuhlbrigge RC, Kieffer JD, Armerding D, Kupper TS. Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing T cells. Nature. 1997 Oct 30; 389(6654):978-81.
    View in: PubMed
  75. Kitayama J, Fuhlbrigge RC, Puri KD, Springer TA. P-selectin, L-selectin, and alpha 4 integrin have distinct roles in eosinophil tethering and arrest on vascular endothelial cells under physiological flow conditions. J Immunol. 1997 Oct 15; 159(8):3929-39.
    View in: PubMed
  76. Chen S, Alon R, Fuhlbrigge RC, Springer TA. Rolling and transient tethering of leukocytes on antibodies reveal specializations of selectins. Proc Natl Acad Sci U S A. 1997 Apr 1; 94(7):3172-7.
    View in: PubMed
  77. 16. Kitayama, J., R.C. Fuhlbrigge, K.D. Puri, and T.A. Springer. . P-selectin, L-selectin, and alpha(4) integrin have distinct roles in eosinophil tethering and arrest on vascular endothelial cells under physiological flow conditions. 1997; Journal of Immunology:159.
  78. Chen, S., R. Alon, R.C. Fuhlbrigge and T.A. Springer. . Rolling and transient tethering of leukocytes on antibodies reveal specialization of selectins. Proceedings of the National Academy of Science USA. 1997; 94:3172-3177.
  79. Fuhlbrigge RC, Alon R, Puri KD, Lowe JB, Springer TA. Sialylated, fucosylated ligands for L-selectin expressed on leukocytes mediate tethering and rolling adhesions in physiologic flow conditions. J Cell Biol. 1996 Nov; 135(3):837-48.
    View in: PubMed
  80. Alon R, Fuhlbrigge RC, Finger EB, Springer TA. Interactions through L-selectin between leukocytes and adherent leukocytes nucleate rolling adhesions on selectins and VCAM-1 in shear flow. J Cell Biol. 1996 Nov; 135(3):849-65.
    View in: PubMed
  81. Bleul CC, Fuhlbrigge RC, Casasnovas JM, Aiuti A, Springer TA. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1) J Exp Med. 1996 Sep 1; 184(3):1101-9.
    View in: PubMed
  82. Alon R., R.C. Fuhlbrigge and T.A. Springer. . Leukocyte ligands for L-selectin nucleate rolling adhesions on vascular selectins and VCAM-1. Journal of Cell Biology. 1996; 135(3):849-865.
  83. Bleuel, C.C., R.C. Fuhlbrigge, J.M. Casasnovas, A. Aiuti and T.A. Springer. . A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1). Journal of Experimental Medicine. 1996; 184:1101-1109.
  84. Alon R, Feizi T, Yuen CT, Fuhlbrigge RC, Springer TA. Glycolipid ligands for selectins support leukocyte tethering and rolling under physiologic flow conditions. J Immunol. 1995 May 15; 154(10):5356-66.
    View in: PubMed
  85. Alon, R., T. Feizi, C.-T. Yuen, R.C. Fuhlbrigge and T.A. Springer. . Glycolipid ligands for selectins support leukocyte tethering and rolling adhesions under physiologic flow conditions. Journal of Immunology. 1995; 154(10):5356-5366 .
  86. Hawrylowicz CM, Duncan LM, Fuhlbrigge RC, Unanue ER. Regulation of antigen presentation. II. Anti-Ig and IL-2 induce IL-1 production by murine splenic B cells. J Immunol. 1989 May 15; 142(10):3361-8.
    View in: PubMed
  87. Fuhlbrigge RC, Hogquist KA, Unanue ER, Chaplin DD. Molecular biology and genetics of interleukin-1. Year Immunol. 1989; 5:21-37.
    View in: PubMed
  88. Hawrylowicz, C.M., L.M. Duncan, R.C. Fuhlbrigge and E.R. Unanue . Regulation of antigen presentation II: Anti-Ig and IL-2 induce IL-1 production by murine splenic B cells. Journal of Immunology. 1989; 142(10):3361-3368.
  89. Fuhlbrigge RC, Sheehan KC, Schreiber RD, Chaplin DD, Unanue ER. Monoclonal antibodies to murine IL-1 alpha. Production, characterization, and inhibition of membrane-associated IL-1 activity. J Immunol. 1988 Oct 15; 141(8):2643-50.
    View in: PubMed
  90. Fuhlbrigge RC, Fine SM, Unanue ER, Chaplin DD. Expression of membrane interleukin 1 by fibroblasts transfected with murine pro-interleukin 1 alpha cDNA. Proc Natl Acad Sci U S A. 1988 Aug; 85(15):5649-53.
    View in: PubMed
  91. Chaplin, D.D., R.C. Fuhlbrigge, S. Jadidi, K.C.F. Sheehan, R.D. Schreiber, P.W. Gray, E.R. Unanue, and P. D'Eustachio. Restriction length polymorphism and linkage of murine IL-1 ƒÑ and ƒÒ genes on chromosome 2. In, Progress in Leukocyte Biology, Vol. 8,. "Monokines and other Non-lymphocytic Cytokines," Editors: M.C. Powanda, J.J. Oppenheim, M.J. Kluger, and C.A. Dinarello. 1988; 41-46.
  92. Fuhlbrigge, R.C., K.C.F. Sheehan, R.D. Schreiber, D.D. Chaplin, and E.R. Unanue. Monoclonal antibodies to murine IL-1Ą: Production, characterization and inhibition of membrane-associated IL-1 activity. Journal of Immunology. 1988; 141(8):2643-2650..
  93. Fuhlbrigge, R.C., K.A. Hogquist, E.R. Unanue, and D.D. Chaplin. 1989. . Molecular biology and genetics of interleukin-1. Editors: J.M. Cruise and R.E. Lewis Jr.(Karger, Basel). The Year in Immunology 1988. 1988; 5:21-37.
  94. Fuhlbrigge, R.C., K.C.F. Sheehan, R.D. Schreiber, D.D. Chaplin, and E.R. Unanue. Monoclonal antibodies to murine IL-1Ą: Production, characterization and inhibition of membrane-associated IL-1 activity. Journal of Immunology. 1988; 141(8):2643-2650.
  95. Fuhlbrigge RC, Chaplin DD, Kiely JM, Unanue ER. Regulation of interleukin 1 gene expression by adherence and lipopolysaccharide. J Immunol. 1987 Jun 1; 138(11):3799-802.
    View in: PubMed
  96. Unanue ER, Weaver CT, Fuhlbrigge RC, Kiely JM, Chaplin DD. Membrane IL-1: a key protein in antigen presentation. Ann Inst Pasteur Immunol. 1987 May-Jun; 138(3):489-92.
    View in: PubMed
  97. D'Eustachio, P., S. Jadidi, R.C. Fuhlbrigge, P.W. Gray, and D.D. Chaplin. Interleukin-1ƒÑ and ƒÒ genes: Linkage on chromosome 2 in the mouse. Immunogenetic. 1987; 26(6):339-343.
  98. D'Eustachio P, Jadidi S, Fuhlbrigge RC, Gray PW, Chaplin DD. Interleukin-1 alpha and beta genes: linkage on chromosome 2 in the mouse. Immunogenetics. 1987; 26(6):339-43.
    View in: PubMed
  99. Robert C. Fuhlbrigge, MD, Ph.D. Membrane Interleukin-1 [dissertation]. 1987.
  100. Edwards BS, Fuhlbrigge RC, Borden EC. Separation of human natural killer cell subpopulations differentially responsive to interferon potentiation. J Interferon Res. 1986 Aug; 6(4):361-72.
    View in: PubMed
  101. Edwards BS, Merritt JA, Fuhlbrigge RC, Borden EC. Low doses of interferon alpha result in more effective clinical natural killer cell activation. J Clin Invest. 1985 Jun; 75(6):1908-13.
    View in: PubMed
  102. Fuhlbrigge RC, Edwards BS, Borden EC. Effects of interferon alpha on the sheep erythrocyte "receptor" of human lymphocytes. J Interferon Res. 1984; 4(4):499-505.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact Human Resources at faculty_serviceshms.harvard.edu.
Fuhlbrigge's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
_
Co-Authors
_
Similar People
_
Same Department
Physical Neighbors
_