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Ildiko Van Rhijn, Ph.D.

TitleLecturer on Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressBrigham and Women's Hospital
Division of Rheumatology, Smith Bldg 514
1 Jimmy Fund Way
Boston MA 02115
Phone617/525-1023
Fax617/525-1010

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Van Rhijn I, Ly D, Moody DB. CD1a, CD1b, and CD1c in Immunity Against Mycobacteria. Adv Exp Med Biol. 2013; 783:181-97.
    View in: PubMed
  2. Seshadri C, Turner MT, Lewinsohn DM, Moody DB, Van Rhijn I. Lipoproteins Are Major Targets of the Polyclonal Human T Cell Response to Mycobacterium tuberculosis. J Immunol. 2013 Jan 1; 190(1):278-84.
    View in: PubMed
  3. Wang J, Guillaume J, Pauwels N, Van Calenbergh S, Van Rhijn I, Zajonc DM. Crystal Structures of Bovine CD1d Reveal Altered aGalCer Presentation and a Restricted A' Pocket Unable to Bind Long-Chain Glycolipids. PLoS One. 2012; 7(10):e47989.
    View in: PubMed
  4. Nguyen TK, Koets AP, Vordermeier M, Jervis PJ, Cox LR, Graham SP, Santema WJ, Moody DB, van Calenbergh S, Zajonc DM, Besra GS, Van Rhijn I. The bovine CD1D gene has an unusual gene structure and is expressed but cannot present a-galactosylceramide with a C26 fatty acid. Int Immunol. 2013 Feb; 25(2):91-8.
    View in: PubMed
  5. Vrieling M, Santema W, Van Rhijn I, Rutten V, Koets A. ?d T cell homing to skin and migration to skin-draining lymph nodes is CCR7 independent. J Immunol. 2012 Jan 15; 188(2):578-84.
    View in: PubMed
  6. Kasmar AG, van Rhijn I, Cheng TY, Turner M, Seshadri C, Schiefner A, Kalathur RC, Annand JW, de Jong A, Shires J, Leon L, Brenner M, Wilson IA, Altman JD, Moody DB. CD1b tetramers bind aß T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans. J Exp Med. 2011 Aug 29; 208(9):1741-7.
    View in: PubMed
  7. Nguyen TK, Wieland W, Santema W, Hoeboer J, van Eden W, Rutten V, Koets A, Van Rhijn I. Immune response of cattle immunized with a conjugate of the glycolipid glucose monomycolate and protein. Vet Immunol Immunopathol. 2011 Aug 15; 142(3-4):265-70.
    View in: PubMed
  8. de Jong A, Peña-Cruz V, Cheng TY, Clark RA, Van Rhijn I, Moody DB. CD1a-autoreactive T cells are a normal component of the human aß T cell repertoire. Nat Immunol. 2010 Dec; 11(12):1102-9.
    View in: PubMed
  9. Girardi E, Wang J, Mac TT, Versluis C, Bhowruth V, Besra G, Heck AJ, Van Rhijn I, Zajonc DM. Crystal structure of bovine CD1b3 with endogenously bound ligands. J Immunol. 2010 Jul 1; 185(1):376-86.
    View in: PubMed
  10. Goldfinch N, Reinink P, Connelley T, Koets A, Morrison I, Van Rhijn I. Conservation of mucosal associated invariant T (MAIT) cells and the MR1 restriction element in ruminants, and abundance of MAIT cells in spleen. Vet Res. 2010 Sep-Oct; 41(5):62.
    View in: PubMed
  11. Van Rhijn I, Nguyen TK, Michel A, Cooper D, Govaerts M, Cheng TY, van Eden W, Moody DB, Coetzer JA, Rutten V, Koets AP. Low cross-reactivity of T-cell responses against lipids from Mycobacterium bovis and M. avium paratuberculosis during natural infection. Eur J Immunol. 2009 Nov; 39(11):3031-41.
    View in: PubMed
  12. Maas M, Van Rhijn I, Allsopp MT, Rutten VP. Lion (Panthera leo) and cheetah (Acinonyx jubatus) IFN-gamma sequences. Vet Immunol Immunopathol. 2010 Apr 15; 134(3-4):296-8.
    View in: PubMed
  13. Reinink P, Van Rhijn I. The bovine T cell receptor alpha/delta locus contains over 400 V genes and encodes V genes without CDR2. Immunogenetics. 2009 Jul; 61(7):541-9.
    View in: PubMed
  14. Kasmar A, Van Rhijn I, Moody DB. The evolved functions of CD1 during infection. Curr Opin Immunol. 2009 Aug; 21(4):397-403.
    View in: PubMed
  15. Nguyen TK, Koets AP, Santema WJ, van Eden W, Rutten VP, Van Rhijn I. The mycobacterial glycolipid glucose monomycolate induces a memory T cell response comparable to a model protein antigen and no B cell response upon experimental vaccination of cattle. Vaccine. 2009 Jul 30; 27(35):4818-25.
    View in: PubMed
  16. Van Rhijn I, Young DC, De Jong A, Vazquez J, Cheng TY, Talekar R, Barral DC, Barral D, León L, Brenner MB, Katz JT, Riese R, Ruprecht RM, O'Connor PB, Costello CE, Porcelli SA, Briken V, Moody DB. CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids. J Exp Med. 2009 Jun 8; 206(6):1409-22.
    View in: PubMed
  17. Looringh van Beeck FA, Reinink P, Hermsen R, Zajonc DM, Laven MJ, Fun A, Troskie M, Schoemaker NJ, Morar D, Lenstra JA, Vervelde L, Rutten VP, van Eden W, Van Rhijn I. Functional CD1d and/or NKT cell invariant chain transcript in horse, pig, African elephant and guinea pig, but not in ruminants. Mol Immunol. 2009 Apr; 46(7):1424-31.
    View in: PubMed
  18. Hoek A, Rutten VP, Kool J, Arkesteijn GJ, Bouwstra RJ, Van Rhijn I, Koets AP. Subpopulations of bovine WC1(+) gammadelta T cells rather than CD4(+)CD25(high) Foxp3(+) T cells act as immune regulatory cells ex vivo. Vet Res. 2009 Jan-Feb; 40(1):6.
    View in: PubMed
  19. Looringh van Beeck FA, Zajonc DM, Moore PF, Schlotter YM, Broere F, Rutten VP, Willemse T, Van Rhijn I. Two canine CD1a proteins are differentially expressed in skin. Immunogenetics. 2008 Jun; 60(6):315-24.
    View in: PubMed
  20. Van Rhijn I, Godfroid J, Michel A, Rutten V. Bovine tuberculosis as a model for human tuberculosis: advantages over small animal models. Microbes Infect. 2008 Jun; 10(7):711-5.
    View in: PubMed
  21. Van Rhijn I, Spiering R, Smits M, van Blokland MT, de Weger R, van Eden W, Rutten VP, Koets AP. Highly diverse TCR delta chain repertoire in bovine tissues due to the use of up to four D segments per delta chain. Mol Immunol. 2007 May; 44(12):3155-61.
    View in: PubMed
  22. Van Rhijn I, Rutten VP, Charleston B, Smits M, van Eden W, Koets AP. Massive, sustained gammadelta T cell migration from the bovine skin in vivo. J Leukoc Biol. 2007 Apr; 81(4):968-73.
    View in: PubMed
  23. Cheng TY, Relloso M, Van Rhijn I, Young DC, Besra GS, Briken V, Zajonc DM, Wilson IA, Porcelli S, Moody DB. Role of lipid trimming and CD1 groove size in cellular antigen presentation. EMBO J. 2006 Jul 12; 25(13):2989-99.
    View in: PubMed
  24. Van Rhijn I, Koets AP, Im JS, Piebes D, Reddington F, Besra GS, Porcelli SA, van Eden W, Rutten VP. The bovine CD1 family contains group 1 CD1 proteins, but no functional CD1d. J Immunol. 2006 Apr 15; 176(8):4888-93.
    View in: PubMed
  25. Van Rhijn I, Zajonc DM, Wilson IA, Moody DB. T-cell activation by lipopeptide antigens. Curr Opin Immunol. 2005 Jun; 17(3):222-9.
    View in: PubMed
  26. Van Rhijn I, Young DC, Im JS, Levery SB, Illarionov PA, Besra GS, Porcelli SA, Gumperz J, Cheng TY, Moody DB. CD1d-restricted T cell activation by nonlipidic small molecules. Proc Natl Acad Sci U S A. 2004 Sep 14; 101(37):13578-83.
    View in: PubMed
  27. Van Rhijn I, Logtenberg T, Ang CW, Van den Berg LH. Gammadelta T cell non-responsiveness in Campylobacter jejuni-associated Guillain-Barré syndrome patients. Neurology. 2003 Oct 14; 61(7):994-6.
    View in: PubMed
  28. Van Rhijn I, Van den Berg LH, Ang CW, Admiraal J, Logtenberg T. Expansion of human gammadelta T cells after in vitro stimulation with Campylobacter jejuni. Int Immunol. 2003 Mar; 15(3):373-82.
    View in: PubMed
  29. Van Rhijn I, Bleumink-Pluym NM, Van Putten JP, Van den Berg LH. Campylobacter DNA is present in circulating myelomonocytic cells of healthy persons and in persons with Guillain-Barré syndrome. J Infect Dis. 2002 Jan 15; 185(2):262-5.
    View in: PubMed
  30. Van Rhijn I, Van den Berg LH, Bosboom WM, Otten HG, Logtenberg T. Expression of accessory molecules for T-cell activation in peripheral nerve of patients with CIDP and vasculitic neuropathy. Brain. 2000 Oct; 123 ( Pt 10):2020-9.
    View in: PubMed
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