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Last Name
Institution

Michael Hamblin, PH.D.

TitleAssociate Professor of Dermatology
InstitutionMassachusetts General Hospital
DepartmentDermatology
AddressMassachusetts General Hospital
Wellman Ctr/Bartlett Bldg 414
40 Blossom St
Boston MA 02114
Phone617/726-6182
Fax617/726-8566
Other Positions
TitleMember of the Affiliated Faculty of the Harvard-MIT Division of Health Sciences and Technology
InstitutionMassachusetts Institute of Technology
DepartmentHealth Sciences and Technology


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Rineh A, Kelso MJ, Vatansever F, Tegos GP, Hamblin MR. Clostridium difficile infection: molecular pathogenesis and novel therapeutics. Expert Rev Anti Infect Ther. 2014 Jan; 12(1):131-50.
    View in: PubMed
  2. Gilaberte Y, Aspiroz C, Alejandre MC, Andres-Ciriano E, Fortuño B, Charlez L, Revillo MJ, Hamblin MR, Rezusta A. Cutaneous sporotrichosis treated with photodynamic therapy: an in vitro and in vivo study. Photomed Laser Surg. 2014 Jan; 32(1):54-7.
    View in: PubMed
  3. Hamblin MR. Can osteoarthritis be treated with light? Arthritis Res Ther. 2013; 15(5):120.
    View in: PubMed
  4. Chibebe Junior J, Sabino CP, Tan X, Junqueira JC, Wang Y, Fuchs BB, Jorge AO, Tegos GP, Hamblin MR, Mylonakis E. Selective photoinactivation of Candida albicans in the non-vertebrate host infection model Galleria mellonella. BMC Microbiol. 2013; 13:217.
    View in: PubMed
  5. Mroz P, Vatansever F, Muchowicz A, Hamblin MR. Photodynamic Therapy of Murine Mastocytoma Induces Specific Immune Responses against the Cancer/Testis Antigen P1A. Cancer Res. 2013 Nov 1; 73(21):6462-70.
    View in: PubMed
  6. Reginato E, Mroz P, Chung H, Kawakubo M, Wolf P, Hamblin MR. Photodynamic therapy plus regulatory T-cell depletion produces immunity against a mouse tumour that expresses a self-antigen. Br J Cancer. 2013 Oct 15; 109(8):2167-74.
    View in: PubMed
  7. Yin R, Dai T, Avci P, Jorge AE, de Melo WC, Vecchio D, Huang YY, Gupta A, Hamblin MR. Light based anti-infectives: ultraviolet C irradiation, photodynamic therapy, blue light, and beyond. Curr Opin Pharmacol. 2013 Oct; 13(5):731-62.
    View in: PubMed
  8. Tegos GP, Hamblin MR. Disruptive innovations: new anti-infectives in the age of resistance. Curr Opin Pharmacol. 2013 Oct; 13(5):673-7.
    View in: PubMed
  9. Ando T, Sato S, Kobayashi H, Nawashiro H, Ashida H, Hamblin MR, Obara M. Low-level laser therapy for spinal cord injury in rats: effects of polarization. J Biomed Opt. 2013 Sep 1; 18(9):98002.
    View in: PubMed
  10. de Melo Wde C, Lee AN, Perussi JR, Hamblin MR. Electroporation enhances antimicrobial photodynamic therapy mediated by the hydrophobic photosensitizer, hypericin. Photodiagnosis Photodyn Ther. 2013 Dec; 10(4):647-50.
    View in: PubMed
  11. St Denis TG, Vecchio D, Zadlo A, Rineh A, Sadasivam M, Avci P, Huang L, Kozinska A, Chandran R, Sarna T, Hamblin MR. Thiocyanate potentiates antimicrobial photodynamic therapy: In situ generation of the sulfur trioxide radical anion by singlet oxygen. Free Radic Biol Med. 2013 Dec; 65:800-10.
    View in: PubMed
  12. Jeon S, Wang M, Tan LS, Cooper T, Hamblin MR, Chiang LY. Synthesis of Photoresponsive Dual NIR Two-Photon Absorptive [60]Fullerene Triads and Tetrads. Molecules. 2013; 18(8):9603-22.
    View in: PubMed
  13. Sperandio FF, Huang YY, Hamblin MR. Antimicrobial Photodynamic Therapy to Kill Gram-negative Bacteria. Recent Pat Antiinfect Drug Discov. 2013 Aug; 8(2):108-20.
    View in: PubMed
  14. Vatansever F, de Melo WC, Avci P, Vecchio D, Sadasivam M, Gupta A, Chandran R, Karimi M, Parizotto NA, Yin R, Tegos GP, Hamblin MR. Antimicrobial strategies centered around reactive oxygen species - bactericidal antibiotics, photodynamic therapy, and beyond. FEMS Microbiol Rev. 2013 Nov; 37(6):955-89.
    View in: PubMed
  15. Garcez AS, Núñez SC, Azambuja N, Fregnani ER, Rodriguez HM, Hamblin MR, Suzuki H, Ribeiro MS. Effects of photodynamic therapy on gram-positive and gram-negative bacterial biofilms by bioluminescence imaging and scanning electron microscopic analysis. Photomed Laser Surg. 2013 Nov; 31(11):519-25.
    View in: PubMed
  16. de Melo WC, Avci P, de Oliveira MN, Gupta A, Vecchio D, Sadasivam M, Chandran R, Huang YY, Yin R, Perussi LR, Tegos GP, Perussi JR, Dai T, Hamblin MR. Photodynamic inactivation of biofilm: taking a lightly colored approach to stubborn infection. Expert Rev Anti Infect Ther. 2013 Jul; 11(7):669-93.
    View in: PubMed
  17. Cury V, Moretti AI, Assis L, Bossini P, de Souza Crusca J, Neto CB, Fangel R, de Souza HP, Hamblin MR, Parizotto NA. Low level laser therapy increases angiogenesis in a model of ischemic skin flap in rats mediated by VEGF, HIF-1a and MMP-2. J Photochem Photobiol B. 2013 Aug 5; 125:164-70.
    View in: PubMed
  18. Avci P, Nyame TT, Gupta GK, Sadasivam M, Hamblin MR. Low-level laser therapy for fat layer reduction: a comprehensive review. Lasers Surg Med. 2013 Aug; 45(6):349-57.
    View in: PubMed
  19. G N, Tan A, Farhatnia Y, Rajadas J, Hamblin MR, Khaw PT, Seifalian AM. Channelrhodopsins: visual regeneration and neural activation by a light switch. N Biotechnol. 2013 Jun 25; 30(5):461-74.
    View in: PubMed
  20. St Denis TG, Hamblin MR. Synthesis, bioanalysis and biodistribution of photosensitizer conjugates for photodynamic therapy. Bioanalysis. 2013 May; 5(9):1099-114.
    View in: PubMed
  21. Gupta A, Dai T, Hamblin MR. Effect of red and near-infrared wavelengths on low-level laser (light) therapy-induced healing of partial-thickness dermal abrasion in mice. Lasers Med Sci. 2014 Jan; 29(1):257-65.
    View in: PubMed
  22. Sperandio FF, Giudice FS, Corrêa L, Pinto DS, Hamblin MR, de Sousa SC. Low-level laser therapy can produce increased aggressiveness of dysplastic and oral cancer cell lines by modulation of Akt/mTOR signaling pathway. J Biophotonics. 2013 Oct; 6(10):839-47.
    View in: PubMed
  23. Kourtesi C, Ball AR, Huang YY, Jachak SM, Vera DM, Khondkar P, Gibbons S, Hamblin MR, Tegos GP. Microbial efflux systems and inhibitors: approaches to drug discovery and the challenge of clinical implementation. Open Microbiol J. 2013; 7:34-52.
    View in: PubMed
  24. Avci P, Gupta A, Sadasivam M, Vecchio D, Pam Z, Pam N, Hamblin MR. Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring. Semin Cutan Med Surg. 2013 Mar; 32(1):41-52.
    View in: PubMed
  25. Tanaka M, Mroz P, Dai T, Huang L, Morimoto Y, Kinoshita M, Yoshihara Y, Shinomiya N, Seki S, Nemoto K, Hamblin MR. Linezolid and Vancomycin Decrease the Therapeutic Effect of Methylene Blue-Photodynamic therapy in a Mouse Model of MRSA Bacterial Arthritis. Photochem Photobiol. 2013 May; 89(3):679-82.
    View in: PubMed
  26. Wang M, Maragani S, Huang L, Jeon S, Canteenwala T, Hamblin MR, Chiang LY. Synthesis of decacationic [60]fullerene decaiodides giving photoinduced production of superoxide radicals and effective PDT-mediation on antimicrobial photoinactivation. Eur J Med Chem. 2013 May; 63:170-84.
    View in: PubMed
  27. Chibebe Junior J, Fuchs BB, Sabino CP, Junqueira JC, Jorge AO, Ribeiro MS, Gilmore MS, Rice LB, Tegos GP, Hamblin MR, Mylonakis E. Photodynamic and Antibiotic Therapy Impair the Pathogenesis of Enterococcus faecium in a Whole Animal Insect Model. PLoS One. 2013; 8(2):e55926.
    View in: PubMed
  28. Dai T, Gupta A, Huang YY, Sherwood ME, Murray CK, Vrahas MS, Kielian T, Hamblin MR. Blue Light Eliminates Community-Acquired Methicillin-Resistant Staphylococcus aureus in Infected Mouse Skin Abrasions. Photomed Laser Surg. 2013 Nov; 31(11):531-8.
    View in: PubMed
  29. Kokel D, Cheung CY, Mills R, Coutinho-Budd J, Huang L, Setola V, Sprague J, Jin S, Jin YN, Huang XP, Bruni G, Woolf CJ, Roth BL, Hamblin MR, Zylka MJ, Milan DJ, Peterson RT. Photochemical activation of TRPA1 channels in neurons and animals. Nat Chem Biol. 2013 Apr; 9(4):257-63.
    View in: PubMed
  30. Huang YY, Vecchio D, Avci P, Yin R, Garcia-Diaz M, Hamblin MR. Melanoma resistance to photodynamic therapy: new insights. Biol Chem. 2013 Feb 1; 394(2):239-50.
    View in: PubMed
  31. Huang YY, Vecchio D, Avci P, Yin R, Garcia-Diaz M, Hamblin MR. Melanoma resistance to photodynamic therapy: new insights. Biol Chem. 2013 Feb 1; 394(2):11-20.
    View in: PubMed
  32. Yang E, Diers JR, Huang YY, Hamblin MR, Lindsey JS, Bocian DF, Holten D. Molecular electronic tuning of photosensitizers to enhance photodynamic therapy: synthetic dicyanobacteriochlorins as a case study. Photochem Photobiol. 2013 May; 89(3):605-18.
    View in: PubMed
  33. Prates RA, Fuchs BB, Mizuno K, Naqvi Q, Kato IT, Ribeiro MS, Mylonakis E, Tegos GP, Hamblin MR. Effect of Virulence Factors on the Photodynamic Inactivation of Cryptococcus neoformans. PLoS One. 2013; 8(1):e54387.
    View in: PubMed
  34. Avci P, Sadasivam M, Gupta A, De Melo WC, Huang YY, Yin R, Chandran R, Kumar R, Otufowora A, Nyame T, Hamblin MR. Animal models of skin disease for drug discovery. Expert Opin Drug Discov. 2013 Mar; 8(3):331-55.
    View in: PubMed
  35. Xuan W, Vatansever F, Huang L, Wu Q, Xuan Y, Dai T, Ando T, Xu T, Huang YY, Hamblin MR. Transcranial low-level laser therapy improves neurological performance in traumatic brain injury in mice: effect of treatment repetition regimen. PLoS One. 2013; 8(1):e53454.
    View in: PubMed
  36. Huang YY, Nagata K, Tedford CE, McCarthy T, Hamblin MR. Low-level laser therapy (LLLT) reduces oxidative stress in primary cortical neurons in vitro. J Biophotonics. 2013 Oct; 6(10):829-38.
    View in: PubMed
  37. Dai T, Gupta A, Huang YY, Yin R, Murray CK, Vrahas MS, Sherwood ME, Tegos GP, Hamblin MR. Blue Light Rescues Mice from Potentially Fatal Pseudomonas aeruginosa Burn Infection: Efficacy, Safety, and Mechanism of Action. Antimicrob Agents Chemother. 2013 Mar; 57(3):1238-45.
    View in: PubMed
  38. Aquino AE, Sene-Fiorese M, Paolillo FR, Duarte FO, Oishi JC, Pena AA, Duarte AC, Hamblin MR, Bagnato VS, Parizotto NA. Low-level laser therapy (LLLT) combined with swimming training improved the lipid profile in rats fed with high-fat diet. Lasers Med Sci. 2013 Sep; 28(5):1271-80.
    View in: PubMed
  39. Kato IT, Prates RA, Sabino CP, Fuchs BB, Tegos GP, Mylonakis E, Hamblin MR, Ribeiro MS. Antimicrobial Photodynamic Inactivation Inhibits Candida albicans Virulence Factors and Reduces In Vivo Pathogenicity. Antimicrob Agents Chemother. 2013 Jan; 57(1):445-51.
    View in: PubMed
  40. Sperandio FF, Sharma SK, Wang M, Jeon S, Huang YY, Dai T, Nayka S, de Sousa SC, Chiang LY, Hamblin MR. Photoinduced electron-transfer mechanisms for radical-enhanced photodynamic therapy mediated by water-soluble decacationic C70 and C84O2 Fullerene Derivatives. Nanomedicine. 2013 May; 9(4):570-9.
    View in: PubMed
  41. Huang YY, Balasubramanian T, Yang E, Luo D, Diers JR, Bocian DF, Lindsey JS, Holten D, Hamblin MR. Stable Synthetic Bacteriochlorins for Photodynamic Therapy: Role of Dicyano Peripheral Groups, Central Metal Substitution (2H, Zn, Pd), and Cremophor EL Delivery. ChemMedChem. 2012 Dec; 7(12):2155-67.
    View in: PubMed
  42. Denis TG, Dai T, Hamblin MR. Killing bacterial spores with blue light: when innate resistance meets the power of light. Photochem Photobiol. 2013 Jan; 89(1):2-4.
    View in: PubMed
  43. Huang L, St Denis TG, Xuan Y, Huang YY, Tanaka M, Zadlo A, Sarna T, Hamblin MR. Paradoxical potentiation of methylene blue-mediated antimicrobial photodynamic inactivation by sodium azide: Role of ambient oxygen and azide radicals. Free Radic Biol Med. 2012 Dec 1; 53(11):2062-71.
    View in: PubMed
  44. Assis L, Moretti AI, Abrahão TB, Cury V, Souza HP, Hamblin MR, Parizotto NA. Low-level laser therapy (808?nm) reduces inflammatory response and oxidative stress in rat tibialis anterior muscle after cryolesion. Lasers Surg Med. 2012 Nov; 44(9):726-35.
    View in: PubMed
  45. Vecchio D, Dai T, Huang L, Fantetti L, Roncucci G, Hamblin MR. Antimicrobial photodynamic therapy with RLP068 kills methicillin-resistant Staphylococcus aureus and improves wound healing in a mouse model of infected skin abrasion PDT with RLP068/Cl in infected mouse skin abrasion. J Biophotonics. 2013 Sep; 6(9):733-42.
    View in: PubMed
  46. Dai T, Murray CK, Vrahas MS, Baer DG, Tegos GP, Hamblin MR. Ultraviolet C light for Acinetobacter baumannii wound infections in mice: potential use for battlefield wound decontamination? J Trauma Acute Care Surg. 2012 Sep; 73(3):661-7.
    View in: PubMed
  47. Gupta A, Avci P, Sadasivam M, Chandran R, Parizotto N, Vecchio D, de Melo WC, Dai T, Chiang LY, Hamblin MR. Shining light on nanotechnology to help repair and regeneration. Biotechnol Adv. 2013 Sep-Oct; 31(5):607-31.
    View in: PubMed
  48. Assis L, Moretti AI, Abrahão TB, de Souza HP, Hamblin MR, Parizotto NA. Low-level laser therapy (808 nm) contributes to muscle regeneration and prevents fibrosis in rat tibialis anterior muscle after cryolesion. Lasers Med Sci. 2013 May; 28(3):947-55.
    View in: PubMed
  49. Demidova-Rice TN, Hamblin MR, Herman IM. Acute and impaired wound healing: pathophysiology and current methods for drug delivery, part 2: role of growth factors in normal and pathological wound healing: therapeutic potential and methods of delivery. Adv Skin Wound Care. 2012 Aug; 25(8):349-70.
    View in: PubMed
  50. Baxter RM, Dai T, Kimball J, Wang E, Hamblin MR, Wiesmann WP, McCarthy SJ, Baker SM. Chitosan dressing promotes healing in third degree burns in mice: Gene expression analysis shows biphasic effects for rapid tissue regeneration and decreased fibrotic signaling. J Biomed Mater Res A. 2013 Feb; 101(2):340-8.
    View in: PubMed
  51. Dai T, Gupta A, Murray CK, Vrahas MS, Tegos GP, Hamblin MR. Blue light for infectious diseases: Propionibacterium acnes, Helicobacter pylori, and beyond? Drug Resist Updat. 2012 Aug; 15(4):223-36.
    View in: PubMed
  52. García-Díaz M, Kawakubo M, Mroz P, Sagristà ML, Mora M, Nonell S, Hamblin MR. Cellular and vascular effects of the photodynamic agent temocene are modulated by the delivery vehicle. J Control Release. 2012 Sep 10; 162(2):355-63.
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  53. Hamrahi V, Hamblin MR, Jung W, Benjamin JB, Paul KW, Fischman AJ, Tompkins RG, Carter EA. Gram-negative bacterial infection in thigh abscess can migrate to distant burn depending on burn depth. Interdiscip Perspect Infect Dis. 2012; 2012:567140.
    View in: PubMed
  54. Huang YY, Gupta A, Vecchio D, Arce VJ, Huang SF, Xuan W, Hamblin MR. Transcranial low level laser (light) therapy for traumatic brain injury. J Biophotonics. 2012 Nov; 5(11-12):827-37.
    View in: PubMed
  55. Shrestha A, Hamblin MR, Kishen A. Characterization of a conjugate between Rose Bengal and chitosan for targeted antibiofilm and tissue stabilization effects as a potential treatment of infected dentin. Antimicrob Agents Chemother. 2012 Sep; 56(9):4876-84.
    View in: PubMed
  56. Huang L, Xuan Y, Koide Y, Zhiyentayev T, Tanaka M, Hamblin MR. Type I and Type II mechanisms of antimicrobial photodynamic therapy: an in vitro study on gram-negative and gram-positive bacteria. Lasers Surg Med. 2012 Aug; 44(6):490-9.
    View in: PubMed
  57. Demidova-Rice TN, Hamblin MR, Herman IM. Acute and impaired wound healing: pathophysiology and current methods for drug delivery, part 1: normal and chronic wounds: biology, causes, and approaches to care. Adv Skin Wound Care. 2012 Jul; 25(7):304-14.
    View in: PubMed
  58. Huang YY, Tanaka M, Vecchio D, Garcia-Diaz M, Chang J, Morimoto Y, Hamblin MR. Photodynamic therapy induces an immune response against a bacterial pathogen. Expert Rev Clin Immunol. 2012 Jul; 8(5):479-94.
    View in: PubMed
  59. Kawakubo M, Eguchi K, Arai T, Kobayashi K, Hamblin MR. Surface layer-preserving photodynamic therapy (SPPDT) in a subcutaneous mouse model of lung cancer. Lasers Surg Med. 2012 Aug; 44(6):500-7.
    View in: PubMed
  60. Tanaka M, Mroz P, Dai T, Huang L, Morimoto Y, Kinoshita M, Yoshihara Y, Nemoto K, Shinomiya N, Seki S, Hamblin MR. Photodynamic therapy can induce a protective innate immune response against murine bacterial arthritis via neutrophil accumulation. PLoS One. 2012; 7(6):e39823.
    View in: PubMed
  61. Dai T, Garcia B, Murray CK, Vrahas MS, Hamblin MR. UVC light prophylaxis for cutaneous wound infections in mice. Antimicrob Agents Chemother. 2012 Jul; 56(7):3841-8.
    View in: PubMed
  62. Thota S, Wang M, Jeon S, Maragani S, Hamblin MR, Chiang LY. Synthesis and characterization of positively charged pentacationic [60]fullerene monoadducts for antimicrobial photodynamic inactivation. Molecules. 2012; 17(5):5225-43.
    View in: PubMed
  63. Wang M, Huang L, Sharma SK, Jeon S, Thota S, Sperandio FF, Nayka S, Chang J, Hamblin MR, Chiang LY. Synthesis and photodynamic effect of new highly photostable decacationically armed [60]- and [70]fullerene decaiodide monoadducts to target pathogenic bacteria and cancer cells. J Med Chem. 2012 May 10; 55(9):4274-85.
    View in: PubMed
  64. Hamblin MR. Antimicrobial photodynamic therapy and photodynamic inactivation, or killing bugs with dyes and light--a symposium-in-print. Photochem Photobiol. 2012 May-Jun; 88(3):496-8.
    View in: PubMed
  65. Dai T, Fuchs BB, Coleman JJ, Prates RA, Astrakas C, St Denis TG, Ribeiro MS, Mylonakis E, Hamblin MR, Tegos GP. Concepts and principles of photodynamic therapy as an alternative antifungal discovery platform. Front Microbiol. 2012; 3:120.
    View in: PubMed
  66. Demidova-Rice TN, Wolf L, Deckenback J, Hamblin MR, Herman IM. Human platelet-rich plasma- and extracellular matrix-derived peptides promote impaired cutaneous wound healing in vivo. PLoS One. 2012; 7(2):e32146.
    View in: PubMed
  67. Vera DM, Haynes MH, Ball AR, Dai T, Astrakas C, Kelso MJ, Hamblin MR, Tegos GP. Strategies to potentiate antimicrobial photoinactivation by overcoming resistant phenotypes. Photochem Photobiol. 2012 May-Jun; 88(3):499-511.
    View in: PubMed
  68. Dai T, Vrahas MS, Murray CK, Hamblin MR. Ultraviolet C irradiation: an alternative antimicrobial approach to localized infections? Expert Rev Anti Infect Ther. 2012 Feb; 10(2):185-95.
    View in: PubMed
  69. Wu Q, Xuan W, Ando T, Xu T, Huang L, Huang YY, Dai T, Dhital S, Sharma SK, Whalen MJ, Hamblin MR. Low-level laser therapy for closed-head traumatic brain injury in mice: effect of different wavelengths. Lasers Surg Med. 2012 Mar; 44(3):218-26.
    View in: PubMed
  70. Sharma SK, Chiang LY, Hamblin MR. Photodynamic therapy with fullerenes in vivo: reality or a dream? Nanomedicine (Lond). 2011 Dec; 6(10):1813-25.
    View in: PubMed
  71. Chung H, Dai T, Sharma SK, Huang YY, Carroll JD, Hamblin MR. The nuts and bolts of low-level laser (light) therapy. Ann Biomed Eng. 2012 Feb; 40(2):516-33.
    View in: PubMed
  72. St Denis TG, Dai T, Izikson L, Astrakas C, Anderson RR, Hamblin MR, Tegos GP. All you need is light: antimicrobial photoinactivation as an evolving and emerging discovery strategy against infectious disease. Virulence. 2011 Nov-Dec; 2(6):509-20.
    View in: PubMed
  73. Tanaka M, Kinoshita M, Yoshihara Y, Shinomiya N, Seki S, Nemoto K, Hirayama T, Dai T, Huang L, Hamblin MR, Morimoto Y. Optimal photosensitizers for photodynamic therapy of infections should kill bacteria but spare neutrophils. Photochem Photobiol. 2012 Jan-Feb; 88(1):227-32.
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  74. Apidianakis Y, Que YA, Xu W, Tegos GP, Zimniak P, Hamblin MR, Tompkins RG, Xiao W, Rahme LG. Down-regulation of glutatione S-transferase a 4 (hGSTA4) in the muscle of thermally injured patients is indicative of susceptibility to bacterial infection. FASEB J. 2012 Feb; 26(2):730-7.
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  75. Ando T, Xuan W, Xu T, Dai T, Sharma SK, Kharkwal GB, Huang YY, Wu Q, Whalen MJ, Sato S, Obara M, Hamblin MR. Comparison of therapeutic effects between pulsed and continuous wave 810-nm wavelength laser irradiation for traumatic brain injury in mice. PLoS One. 2011; 6(10):e26212.
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  76. Li P, Zhou G, Zhu X, Li G, Yan P, Shen L, Xu Q, Hamblin MR. Photodynamic therapy with hyperbranched poly(ether-ester) chlorin(e6) nanoparticles on human tongue carcinoma CAL-27 cells. Photodiagnosis Photodyn Ther. 2012 Mar; 9(1):76-82.
    View in: PubMed
  77. Penjweini R, Loew HG, Hamblin MR, Kratky KW. Long-term monitoring of live cell proliferation in presence of PVP-Hypericin: a new strategy using ms pulses of LED and the fluorescent dye CFSE. J Microsc. 2012 Jan; 245(1):100-8.
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  78. Dai T, Bil de Arce VJ, Tegos GP, Hamblin MR. Blue dye and red light, a dynamic combination for prophylaxis and treatment of cutaneous Candida albicans infections in mice. Antimicrob Agents Chemother. 2011 Dec; 55(12):5710-7.
    View in: PubMed
  79. Huang YY, Sharma SK, Carroll J, Hamblin MR. Biphasic dose response in low level light therapy - an update. Dose Response. 2011; 9(4):602-18.
    View in: PubMed
  80. Kharkwal GB, Sharma SK, Huang YY, Dai T, Hamblin MR. Photodynamic therapy for infections: clinical applications. Lasers Surg Med. 2011 Sep; 43(7):755-67.
    View in: PubMed
  81. Sharma SK, Kharkwal GB, Sajo M, Huang YY, De Taboada L, McCarthy T, Hamblin MR. Dose response effects of 810 nm laser light on mouse primary cortical neurons. Lasers Surg Med. 2011 Sep; 43(8):851-9.
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  82. Chen AC, Arany PR, Huang YY, Tomkinson EM, Sharma SK, Kharkwal GB, Saleem T, Mooney D, Yull FE, Blackwell TS, Hamblin MR. Low-level laser therapy activates NF-kB via generation of reactive oxygen species in mouse embryonic fibroblasts. PLoS One. 2011; 6(7):e22453.
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  83. Naeser MA, Hamblin MR. Potential for transcranial laser or LED therapy to treat stroke, traumatic brain injury, and neurodegenerative disease. Photomed Laser Surg. 2011 Jul; 29(7):443-6.
    View in: PubMed
  84. Dai T, Tanaka M, Huang YY, Hamblin MR. Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects. Expert Rev Anti Infect Ther. 2011 Jul; 9(7):857-79.
    View in: PubMed
  85. Dai T, Kharkwal GB, Tanaka M, Huang YY, Bil de Arce VJ, Hamblin MR. Animal models of external traumatic wound infections. Virulence. 2011 Jul-Aug; 2(4):296-315.
    View in: PubMed
  86. Agostinis P, Berg K, Cengel KA, Foster TH, Girotti AW, Gollnick SO, Hahn SM, Hamblin MR, Juzeniene A, Kessel D, Korbelik M, Moan J, Mroz P, Nowis D, Piette J, Wilson BC, Golab J. Photodynamic therapy of cancer: an update. CA Cancer J Clin. 2011 Jul-Aug; 61(4):250-81.
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  87. Mroz P, Xia Y, Asanuma D, Konopko A, Zhiyentayev T, Huang YY, Sharma SK, Dai T, Khan UJ, Wharton T, Hamblin MR. Intraperitoneal photodynamic therapy mediated by a fullerene in a mouse model of abdominal dissemination of colon adenocarcinoma. Nanomedicine. 2011 Dec; 7(6):965-74.
    View in: PubMed
  88. Prates RA, Kato IT, Ribeiro MS, Tegos GP, Hamblin MR. Influence of multidrug efflux systems on methylene blue-mediated photodynamic inactivation of Candida albicans. J Antimicrob Chemother. 2011 Jul; 66(7):1525-32.
    View in: PubMed
  89. Huang L, Dai T, Xuan Y, Tegos GP, Hamblin MR. Synergistic combination of chitosan acetate with nanoparticle silver as a topical antimicrobial: efficacy against bacterial burn infections. Antimicrob Agents Chemother. 2011 Jul; 55(7):3432-8.
    View in: PubMed
  90. Wainwright M, Dai T, Hamblin MR. Antimicrobial photodynamic therapy in the colon: delivering a light punch to the guts? Photochem Photobiol. 2011 Jul-Aug; 87(4):754-6.
    View in: PubMed
  91. St Denis TG, Aziz K, Waheed AA, Huang YY, Sharma SK, Mroz P, Hamblin MR. Combination approaches to potentiate immune response after photodynamic therapy for cancer. Photochem Photobiol Sci. 2011 May; 10(5):792-801.
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  92. Fiamegos YC, Kastritis PL, Exarchou V, Han H, Bonvin AM, Vervoort J, Lewis K, Hamblin MR, Tegos GP. Antimicrobial and efflux pump inhibitory activity of caffeoylquinic acids from Artemisia absinthium against gram-positive pathogenic bacteria. PLoS One. 2011; 6(4):e18127.
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  93. Huang L, Zhiyentayev T, Xuan Y, Azhibek D, Kharkwal GB, Hamblin MR. Photodynamic inactivation of bacteria using polyethylenimine-chlorin(e6) conjugates: Effect of polymer molecular weight, substitution ratio of chlorin(e6) and pH. Lasers Surg Med. 2011 Apr; 43(4):313-23.
    View in: PubMed
  94. Mroz P, Hamblin MR. The immunosuppressive side of PDT. Photochem Photobiol Sci. 2011 May; 10(5):751-8.
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  95. Tanaka M, Kinoshita M, Yoshihara Y, Shinomiya N, Seki S, Nemoto K, Hamblin MR, Morimoto Y. Photodynamic therapy using intra-articular Photofrin for murine MRSA arthritis: biphasic light dose response for neutrophil-mediated antibacterial effect. Lasers Surg Med. 2011 Mar; 43(3):221-9.
    View in: PubMed
  96. St Denis TG, Huang L, Dai T, Hamblin MR. Analysis of the bacterial heat shock response to photodynamic therapy-mediated oxidative stress. Photochem Photobiol. 2011 May-Jun; 87(3):707-13.
    View in: PubMed
  97. Dai T, Kharkwal GB, Zhao J, St Denis TG, Wu Q, Xia Y, Huang L, Sharma SK, d'Enfert C, Hamblin MR. Ultraviolet-C light for treatment of Candida albicans burn infection in mice. Photochem Photobiol. 2011 Mar-Apr; 87(2):342-9.
    View in: PubMed
  98. Chen AC, Huang YY, Sharma SK, Hamblin MR. Effects of 810-nm laser on murine bone-marrow-derived dendritic cells. Photomed Laser Surg. 2011 Jun; 29(6):383-9.
    View in: PubMed
  99. Mroz P, Yaroslavsky A, Kharkwal GB, Hamblin MR. Cell death pathways in photodynamic therapy of cancer. Cancers (Basel). 2011; 3(2):2516-39.
    View in: PubMed
  100. Sharma SK, Dai T, Kharkwal GB, Huang YY, Huang L, De Arce VJ, Tegos GP, Hamblin MR. Drug discovery of antimicrobial photosensitizers using animal models. Curr Pharm Des. 2011; 17(13):1303-19.
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  101. Mroz P, Hashmi JT, Huang YY, Lange N, Hamblin MR. Stimulation of anti-tumor immunity by photodynamic therapy. Expert Rev Clin Immunol. 2011 Jan; 7(1):75-91.
    View in: PubMed
  102. Naeser MA, Saltmarche A, Krengel MH, Hamblin MR, Knight JA. Improved cognitive function after transcranial, light-emitting diode treatments in chronic, traumatic brain injury: two case reports. Photomed Laser Surg. 2011 May; 29(5):351-8.
    View in: PubMed
  103. Mroz P, Szokalska A, Wu MX, Hamblin MR. Photodynamic therapy of tumors can lead to development of systemic antigen-specific immune response. PLoS One. 2010; 5(12):e15194.
    View in: PubMed
  104. Garcez AS, Núñez SC, Baptista MS, Daghastanli NA, Itri R, Hamblin MR, Ribeiro MS. Antimicrobial mechanisms behind photodynamic effect in the presence of hydrogen peroxide. Photochem Photobiol Sci. 2011 Apr; 10(4):483-90.
    View in: PubMed
  105. Hashmi JT, Huang YY, Osmani BZ, Sharma SK, Naeser MA, Hamblin MR. Role of low-level laser therapy in neurorehabilitation. PM R. 2010 Dec; 2(12 Suppl 2):S292-305.
    View in: PubMed
  106. Lu Z, Dai T, Huang L, Kurup DB, Tegos GP, Jahnke A, Wharton T, Hamblin MR. Photodynamic therapy with a cationic functionalized fullerene rescues mice from fatal wound infections. Nanomedicine (Lond). 2010 Dec; 5(10):1525-33.
    View in: PubMed
  107. Dai T, Tegos GP, St Denis TG, Anderson D, Sinofsky E, Hamblin MR. Ultraviolet-C irradiation for prevention of central venous catheter-related infections: an in vitro study. Photochem Photobiol. 2011 Jan-Feb; 87(1):250-5.
    View in: PubMed
  108. Ragàs X, Sánchez-García D, Ruiz-González R, Dai T, Agut M, Hamblin MR, Nonell S. Cationic porphycenes as potential photosensitizers for antimicrobial photodynamic therapy. J Med Chem. 2010 Nov 11; 53(21):7796-803.
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  109. Kishen A, Upadya M, Tegos GP, Hamblin MR. Efflux pump inhibitor potentiates antimicrobial photodynamic inactivation of Enterococcus faecalis biofilm. Photochem Photobiol. 2010 Nov-Dec; 86(6):1343-9.
    View in: PubMed
  110. Hamblin MR. Introduction to experimental and clinical studies using low-level laser (light) therapy (LLLT). Lasers Surg Med. 2010 Aug; 42(6):447-9.
    View in: PubMed
  111. Hashmi JT, Huang YY, Sharma SK, Kurup DB, De Taboada L, Carroll JD, Hamblin MR. Effect of pulsing in low-level light therapy. Lasers Surg Med. 2010 Aug; 42(6):450-66.
    View in: PubMed
  112. Huang L, Huang YY, Mroz P, Tegos GP, Zhiyentayev T, Sharma SK, Lu Z, Balasubramanian T, Krayer M, Ruzié C, Yang E, Kee HL, Kirmaier C, Diers JR, Bocian DF, Holten D, Lindsey JS, Hamblin MR. Stable synthetic cationic bacteriochlorins as selective antimicrobial photosensitizers. Antimicrob Agents Chemother. 2010 Sep; 54(9):3834-41.
    View in: PubMed
  113. Ragàs X, Dai T, Tegos GP, Agut M, Nonell S, Hamblin MR. Photodynamic inactivation of Acinetobacter baumannii using phenothiazinium dyes: in vitro and in vivo studies. Lasers Surg Med. 2010 Jul; 42(5):384-90.
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  114. Chen Z, Zhou S, Chen J, Deng Y, Luo Z, Chen H, Hamblin MR, Huang M. Pentalysine beta-carbonylphthalocyanine zinc: an effective tumor-targeting photosensitizer for photodynamic therapy. ChemMedChem. 2010 Jun 7; 5(6):890-8.
    View in: PubMed
  115. Hamblin MR, Dai T. Can surgical site infections be treated by photodynamic therapy? Photodiagnosis Photodyn Ther. 2010 Jun; 7(2):134-6.
    View in: PubMed
  116. Dai T, Huang YY, Sharma SK, Hashmi JT, Kurup DB, Hamblin MR. Topical antimicrobials for burn wound infections. Recent Pat Antiinfect Drug Discov. 2010 Jun; 5(2):124-51.
    View in: PubMed
  117. Huang YY, Mroz P, Zhiyentayev T, Sharma SK, Balasubramanian T, Ruzié C, Krayer M, Fan D, Borbas KE, Yang E, Kee HL, Kirmaier C, Diers JR, Bocian DF, Holten D, Lindsey JS, Hamblin MR. In vitro photodynamic therapy and quantitative structure-activity relationship studies with stable synthetic near-infrared-absorbing bacteriochlorin photosensitizers. J Med Chem. 2010 May 27; 53(10):4018-27.
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  118. Mroz P, Huang YY, Szokalska A, Zhiyentayev T, Janjua S, Nifli AP, Sherwood ME, Ruzié C, Borbas KE, Fan D, Krayer M, Balasubramanian T, Yang E, Kee HL, Kirmaier C, Diers JR, Bocian DF, Holten D, Lindsey JS, Hamblin MR. Stable synthetic bacteriochlorins overcome the resistance of melanoma to photodynamic therapy. FASEB J. 2010 Sep; 24(9):3160-70.
    View in: PubMed
  119. Coleman JJ, Okoli I, Tegos GP, Holson EB, Wagner FF, Hamblin MR, Mylonakis E. Characterization of plant-derived saponin natural products against Candida albicans. ACS Chem Biol. 2010 Mar 19; 5(3):321-32.
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  120. Park J, Mroz P, Hamblin MR, Yaroslavsky AN. Dye-enhanced multimodal confocal microscopy for noninvasive detection of skin cancers in mouse models. J Biomed Opt. 2010 Mar-Apr; 15(2):026023.
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  121. Dai T, Tegos GP, Zhiyentayev T, Mylonakis E, Hamblin MR. Photodynamic therapy for methicillin-resistant Staphylococcus aureus infection in a mouse skin abrasion model. Lasers Surg Med. 2010 Jan; 42(1):38-44.
    View in: PubMed
  122. Huang L, Dai T, Hamblin MR. Antimicrobial photodynamic inactivation and photodynamic therapy for infections. Methods Mol Biol. 2010; 635:155-73.
    View in: PubMed
  123. Schiffer F, Johnston AL, Ravichandran C, Polcari A, Teicher MH, Webb RH, Hamblin MR. Psychological benefits 2 and 4 weeks after a single treatment with near infrared light to the forehead: a pilot study of 10 patients with major depression and anxiety. Behav Brain Funct. 2009; 5:46.
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  124. Huang L, Terakawa M, Zhiyentayev T, Huang YY, Sawayama Y, Jahnke A, Tegos GP, Wharton T, Hamblin MR. Innovative cationic fullerenes as broad-spectrum light-activated antimicrobials. Nanomedicine. 2010 Jun; 6(3):442-52.
    View in: PubMed
  125. Huang YY, Chen AC, Carroll JD, Hamblin MR. Biphasic dose response in low level light therapy. Dose Response. 2009; 7(4):358-83.
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  126. Dai T, Huang YY, Hamblin MR. Photodynamic therapy for localized infections--state of the art. Photodiagnosis Photodyn Ther. 2009 Sep-Dec; 6(3-4):170-88.
    View in: PubMed
  127. Lembo AJ, Ganz RA, Sheth S, Cave D, Kelly C, Levin P, Kazlas PT, Baldwin PC, Lindmark WR, McGrath JR, Hamblin MR. Treatment of Helicobacter pylori infection with intra-gastric violet light phototherapy: a pilot clinical trial. Lasers Surg Med. 2009 Jul; 41(5):337-44.
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  128. Dai T, Tegos GP, Lu Z, Huang L, Zhiyentayev T, Franklin MJ, Baer DG, Hamblin MR. Photodynamic therapy for Acinetobacter baumannii burn infections in mice. Antimicrob Agents Chemother. 2009 Sep; 53(9):3929-34.
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  129. Szokalska A, Makowski M, Nowis D, Wilczynski GM, Kujawa M, Wójcik C, Mlynarczuk-Bialy I, Salwa P, Bil J, Janowska S, Agostinis P, Verfaillie T, Bugajski M, Gietka J, Issat T, Glodkowska E, Mrówka P, Stoklosa T, Hamblin MR, Mróz P, Jakóbisiak M, Golab J. Proteasome inhibition potentiates antitumor effects of photodynamic therapy in mice through induction of endoplasmic reticulum stress and unfolded protein response. Cancer Res. 2009 May 15; 69(10):4235-43.
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  130. Mroz P, Bhaumik J, Dogutan DK, Aly Z, Kamal Z, Khalid L, Kee HL, Bocian DF, Holten D, Lindsey JS, Hamblin MR. Imidazole metalloporphyrins as photosensitizers for photodynamic therapy: role of molecular charge, central metal and hydroxyl radical production. Cancer Lett. 2009 Sep 8; 282(1):63-76.
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  131. George S, Hamblin MR, Kishen A. Uptake pathways of anionic and cationic photosensitizers into bacteria. Photochem Photobiol Sci. 2009 Jun; 8(6):788-95.
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  132. Dai T, Tegos GP, Burkatovskaya M, Castano AP, Hamblin MR. Chitosan acetate bandage as a topical antimicrobial dressing for infected burns. Antimicrob Agents Chemother. 2009 Feb; 53(2):393-400.
    View in: PubMed
  133. Tegos GP, Masago K, Aziz F, Higginbotham A, Stermitz FR, Hamblin MR. Inhibitors of bacterial multidrug efflux pumps potentiate antimicrobial photoinactivation. Antimicrob Agents Chemother. 2008 Sep; 52(9):3202-9.
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  134. Burkatovskaya M, Castano AP, Demidova-Rice TN, Tegos GP, Hamblin MR. Effect of chitosan acetate bandage on wound healing in infected and noninfected wounds in mice. Wound Repair Regen. 2008 May-Jun; 16(3):425-31.
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  135. Dai T, Tegos GP, Rolz-Cruz G, Cumbie WE, Hamblin MR. Ultraviolet C inactivation of dermatophytes: implications for treatment of onychomycosis. Br J Dermatol. 2008 Jun; 158(6):1239-46.
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  136. Castano AP, Mroz P, Wu MX, Hamblin MR. Photodynamic therapy plus low-dose cyclophosphamide generates antitumor immunity in a mouse model. Proc Natl Acad Sci U S A. 2008 Apr 8; 105(14):5495-500.
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  137. Wang XL, Wang HW, Hillemanns P, Hamblin MR. Distinctive features of foreskin condylomata acuminata associated with diabetes mellitus. Acta Derm Venereol. 2008; 88(6):578-83.
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  138. Apidianakis Y, Mindrinos MN, Xiao W, Tegos GP, Papisov MI, Hamblin MR, Davis RW, Tompkins RG, Rahme LG. Involvement of skeletal muscle gene regulatory network in susceptibility to wound infection following trauma. PLoS One. 2007; 2(12):e1356.
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  139. Garcez AS, Nuñez SC, Hamblin MR, Ribeiro MS. Antimicrobial effects of photodynamic therapy on patients with necrotic pulps and periapical lesion. J Endod. 2008 Feb; 34(2):138-42.
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  140. Tawakol A, Castano AP, Gad F, Zahra T, Bashian G, Migrino RQ, Ahmadi A, Stern J, Anatelli F, Chirico S, Shirazi A, Syed S, Fischman AJ, Muller JE, Hamblin MR. Intravascular detection of inflamed atherosclerotic plaques using a fluorescent photosensitizer targeted to the scavenger receptor. Photochem Photobiol Sci. 2008 Jan; 7(1):33-9.
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  141. Mroz P, Tegos GP, Gali H, Wharton T, Sarna T, Hamblin MR. Photodynamic therapy with fullerenes. Photochem Photobiol Sci. 2007 Nov; 6(11):1139-49.
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  142. Demidova-Rice TN, Salomatina EV, Yaroslavsky AN, Herman IM, Hamblin MR. Low-level light stimulates excisional wound healing in mice. Lasers Surg Med. 2007 Oct; 39(9):706-15.
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  143. Castano AP, Dai T, Yaroslavsky I, Cohen R, Apruzzese WA, Smotrich MH, Hamblin MR. Low-level laser therapy for zymosan-induced arthritis in rats: Importance of illumination time. Lasers Surg Med. 2007 Jul; 39(6):543-50.
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  144. Fuchs BB, Tegos GP, Hamblin MR, Mylonakis E. Susceptibility of Cryptococcus neoformans to photodynamic inactivation is associated with cell wall integrity. Antimicrob Agents Chemother. 2007 Aug; 51(8):2929-36.
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  145. Mroz P, Pawlak A, Satti M, Lee H, Wharton T, Gali H, Sarna T, Hamblin MR. Functionalized fullerenes mediate photodynamic killing of cancer cells: Type I versus Type II photochemical mechanism. Free Radic Biol Med. 2007 Sep 1; 43(5):711-9.
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  146. Tang HM, Hamblin MR, Yow CM. A comparative in vitro photoinactivation study of clinical isolates of multidrug-resistant pathogens. J Infect Chemother. 2007 Apr; 13(2):87-91.
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  147. Møller-Kristensen M, Hamblin MR, Thiel S, Jensenius JC, Takahashi K. Burn injury reveals altered phenotype in mannan-binding lectin-deficient mice. J Invest Dermatol. 2007 Jun; 127(6):1524-31.
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  148. Garcez AS, Ribeiro MS, Tegos GP, Núñez SC, Jorge AO, Hamblin MR. Antimicrobial photodynamic therapy combined with conventional endodontic treatment to eliminate root canal biofilm infection. Lasers Surg Med. 2007 Jan; 39(1):59-66.
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  149. Garcez AS, Nunez SC, Lage-Marques JL, Hamblin MR, Ribeiro MS. Photonic real-time monitoring of bacterial reduction in root canals by genetically engineered bacteria after chemomechanical endodontic therapy. Braz Dent J. 2007; 18(3):202-7.
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  150. Anatelli F, Mroz P, Liu Q, Yang C, Castano AP, Swietlik E, Hamblin MR. Macrophage-targeted photosensitizer conjugate delivered by intratumoral injection. Mol Pharm. 2006 Nov-Dec; 3(6):654-64.
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  151. Foley JW, Song X, Demidova TN, Jalil F, Jilal F, Hamblin MR. Synthesis and properties of benzo[a]phenoxazinium chalcogen analogues as novel broad-spectrum antimicrobial photosensitizers. J Med Chem. 2006 Aug 24; 49(17):5291-9.
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  152. Castano AP, Mroz P, Hamblin MR. Photodynamic therapy and anti-tumour immunity. Nat Rev Cancer. 2006 Jul; 6(7):535-45.
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  153. Borbas KE, Mroz P, Hamblin MR, Lindsey JS. Bioconjugatable porphyrins bearing a compact swallowtail motif for water solubility. Bioconjug Chem. 2006 May-Jun; 17(3):638-53.
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  154. Burkatovskaya M, Tegos GP, Swietlik E, Demidova TN, P Castano A, Hamblin MR. Use of chitosan bandage to prevent fatal infections developing from highly contaminated wounds in mice. Biomaterials. 2006 Aug; 27(22):4157-64.
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  155. Tegos GP, Anbe M, Yang C, Demidova TN, Satti M, Mroz P, Janjua S, Gad F, Hamblin MR. Protease-stable polycationic photosensitizer conjugates between polyethyleneimine and chlorin(e6) for broad-spectrum antimicrobial photoinactivation. Antimicrob Agents Chemother. 2006 Apr; 50(4):1402-10.
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  156. Tawakol A, Castano AP, Anatelli F, Bashian G, Stern J, Zahra T, Gad F, Chirico S, Ahmadi A, Fischman AJ, Muller JE, Hamblin MR. Photosensitizer delivery to vulnerable atherosclerotic plaque: comparison of macrophage-targeted conjugate versus free chlorin(e6). J Biomed Opt. 2006 Mar-Apr; 11(2):021008.
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  157. Castano AP, Liu Q, Hamblin MR. A green fluorescent protein-expressing murine tumour but not its wild-type counterpart is cured by photodynamic therapy. Br J Cancer. 2006 Feb 13; 94(3):391-7.
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  158. Møller-Kristensen M, Ip WK, Shi L, Gowda LD, Hamblin MR, Thiel S, Jensenius JC, Ezekowitz RA, Takahashi K. Deficiency of mannose-binding lectin greatly increases susceptibility to postburn infection with Pseudomonas aeruginosa. J Immunol. 2006 Feb 1; 176(3):1769-75.
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  159. Tegos GP, Hamblin MR. Phenothiazinium antimicrobial photosensitizers are substrates of bacterial multidrug resistance pumps. Antimicrob Agents Chemother. 2006 Jan; 50(1):196-203.
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  160. Demidova TN, Hamblin MR. Photodynamic inactivation of Bacillus spores, mediated by phenothiazinium dyes. Appl Environ Microbiol. 2005 Nov; 71(11):6918-25.
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  161. Demidova TN, Gad F, Zahra T, Francis KP, Hamblin MR. Monitoring photodynamic therapy of localized infections by bioluminescence imaging of genetically engineered bacteria. J Photochem Photobiol B. 2005 Oct 3; 81(1):15-25.
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  162. Tegos GP, Demidova TN, Arcila-Lopez D, Lee H, Wharton T, Gali H, Hamblin MR. Cationic fullerenes are effective and selective antimicrobial photosensitizers. Chem Biol. 2005 Oct; 12(10):1127-35.
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  163. Liu Q, Hamblin MR. Macrophage-targeted photodynamic therapy: scavenger receptor expression and activation state. Int J Immunopathol Pharmacol. 2005 Jul-Sep; 18(3):391-402.
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  164. Hamblin MR, Viveiros J, Yang C, Ahmadi A, Ganz RA, Tolkoff MJ. Helicobacter pylori accumulates photoactive porphyrins and is killed by visible light. Antimicrob Agents Chemother. 2005 Jul; 49(7):2822-7.
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  165. Lambrechts SA, Demidova TN, Aalders MC, Hasan T, Hamblin MR. Photodynamic therapy for Staphylococcus aureus infected burn wounds in mice. Photochem Photobiol Sci. 2005 Jul; 4(7):503-9.
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  166. Demidova TN, Hamblin MR. Effect of cell-photosensitizer binding and cell density on microbial photoinactivation. Antimicrob Agents Chemother. 2005 Jun; 49(6):2329-35.
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  167. Ganz RA, Viveiros J, Ahmad A, Ahmadi A, Khalil A, Tolkoff MJ, Nishioka NS, Hamblin MR. Helicobacter pylori in patients can be killed by visible light. Lasers Surg Med. 2005 Apr; 36(4):260-5.
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  168. Demidova TN, Hamblin MR. Photodynamic therapy targeted to pathogens. Int J Immunopathol Pharmacol. 2004 Sep-Dec; 17(3):245-54.
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  169. Gad F, Zahra T, Hasan T, Hamblin MR. Effects of growth phase and extracellular slime on photodynamic inactivation of gram-positive pathogenic bacteria. Antimicrob Agents Chemother. 2004 Jun; 48(6):2173-8.
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  170. Shi L, Takahashi K, Dundee J, Shahroor-Karni S, Thiel S, Jensenius JC, Gad F, Hamblin MR, Sastry KN, Ezekowitz RA. Mannose-binding lectin-deficient mice are susceptible to infection with Staphylococcus aureus. J Exp Med. 2004 May 17; 199(10):1379-90.
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  171. Demidova TN, Hamblin MR. Macrophage-targeted photodynamic therapy. Int J Immunopathol Pharmacol. 2004 May-Aug; 17(2):117-26.
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  172. Hamblin MR, Hasan T. Photodynamic therapy: a new antimicrobial approach to infectious disease? Photochem Photobiol Sci. 2004 May; 3(5):436-50.
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  173. Gad F, Zahra T, Francis KP, Hasan T, Hamblin MR. Targeted photodynamic therapy of established soft-tissue infections in mice. Photochem Photobiol Sci. 2004 May; 3(5):451-8.
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  174. Khadem J, Martino M, Anatelli F, Dana MR, Hamblin MR. Healing of perforating rat corneal incisions closed with photodynamic laser-activated tissue glue. Lasers Surg Med. 2004; 35(4):304-11.
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  175. Hamblin MR, Miller JL, Rizvi I, Loew HG, Hasan T. Pegylation of charged polymer-photosensitiser conjugates: effects on photodynamic efficacy. Br J Cancer. 2003 Sep 1; 89(5):937-43.
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  176. Hamblin MR, Zahra T, Contag CH, McManus AT, Hasan T. Optical monitoring and treatment of potentially lethal wound infections in vivo. J Infect Dis. 2003 Jun 1; 187(11):1717-25.
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  177. Kodama T, Doukas AG, Hamblin MR. Delivery of ribosome-inactivating protein toxin into cancer cells with shock waves. Cancer Lett. 2003 Jan 10; 189(1):69-75.
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  178. Hamblin MR, O'Donnell DA, Murthy N, Rajagopalan K, Michaud N, Sherwood ME, Hasan T. Polycationic photosensitizer conjugates: effects of chain length and Gram classification on the photodynamic inactivation of bacteria. J Antimicrob Chemother. 2002 Jun; 49(6):941-51.
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  179. Kodama T, Doukas AG, Hamblin MR. Shock wave-mediated molecular delivery into cells. Biochim Biophys Acta. 2002 Jan 30; 1542(1-3):186-94.
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  180. Hamblin MR, O'Donnell DA, Murthy N, Contag CH, Hasan T. Rapid control of wound infections by targeted photodynamic therapy monitored by in vivo bioluminescence imaging. Photochem Photobiol. 2002 Jan; 75(1):51-7.
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  181. Hamblin MR, Miller JL, Rizvi I, Ortel B. Degree of substitution of chlorin e6 on charged poly-L-lysine chains affects their cellular uptake, localization and phototoxicity towards macrophages and cancer cells. J Xray Sci Technol. 2002 Jan 1; 10(3):139-52.
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  182. Hamblin MR, Miller JL, Rizvi I, Ortel B, Maytin EV, Hasan T. Pegylation of a chlorin(e6) polymer conjugate increases tumor targeting of photosensitizer. Cancer Res. 2001 Oct 1; 61(19):7155-62.
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  183. Soukos NS, Hamblin MR, Keel S, Fabian RL, Deutsch TF, Hasan T. Epidermal growth factor receptor-targeted immunophotodiagnosis and photoimmunotherapy of oral precancer in vivo. Cancer Res. 2001 Jun 1; 61(11):4490-6.
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  184. Hamblin MR, Del Governatore M, Rizvi I, Hasan T. Biodistribution of charged 17.1A photoimmunoconjugates in a murine model of hepatic metastasis of colorectal cancer. Br J Cancer. 2000 Dec; 83(11):1544-51.
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  185. Hamblin MR, Miller JL, Ortel B. Scavenger-receptor targeted photodynamic therapy. Photochem Photobiol. 2000 Oct; 72(4):533-40.
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  186. Kodama T, Hamblin MR, Doukas AG. Cytoplasmic molecular delivery with shock waves: importance of impulse. Biophys J. 2000 Oct; 79(4):1821-32.
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  187. Del Governatore M, Hamblin MR, Shea CR, Rizvi I, Molpus KG, Tanabe KK, Hasan T. Experimental photoimmunotherapy of hepatic metastases of colorectal cancer with a 17.1A chlorin(e6) immunoconjugate. Cancer Res. 2000 Aug 1; 60(15):4200-5.
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  188. Molpus KL, Hamblin MR, Rizvi I, Hasan T. Intraperitoneal photoimmunotherapy of ovarian carcinoma xenografts in nude mice using charged photoimmunoconjugates. Gynecol Oncol. 2000 Mar; 76(3):397-404.
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  189. Del Governatore M, Hamblin MR, Piccinini EE, Ugolini G, Hasan T. Targeted photodestruction of human colon cancer cells using charged 17.1A chlorin e6 immunoconjugates. Br J Cancer. 2000 Jan; 82(1):56-64.
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  190. Khadem J, Veloso AA, Tolentino F, Hasan T, Hamblin MR. Photodynamic tissue adhesion with chlorin(e6) protein conjugates. Invest Ophthalmol Vis Sci. 1999 Dec; 40(13):3132-7.
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  191. Duska LR, Hamblin MR, Miller JL, Hasan T. Combination photoimmunotherapy and cisplatin: effects on human ovarian cancer ex vivo. J Natl Cancer Inst. 1999 Sep 15; 91(18):1557-63.
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  192. Hamblin MR, Rajadhyaksha M, Momma T, Soukos NS, Hasan T. In vivo fluorescence imaging of the transport of charged chlorin e6 conjugates in a rat orthotopic prostate tumour. Br J Cancer. 1999 Sep; 81(2):261-8.
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  193. Thornton PD, Hamblin M, Treleaven JG, Matutes E, Lakhani AK, Catovsky D. High dose methyl prednisolone in refractory chronic lymphocytic leukaemia. Leuk Lymphoma. 1999 Jun; 34(1-2):167-70.
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  194. Momma T, Hamblin MR, Wu HC, Hasan T. Photodynamic therapy of orthotopic prostate cancer with benzoporphyrin derivative: local control and distant metastasis. Cancer Res. 1998 Dec 1; 58(23):5425-31.
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  195. Hamblin MR, Bamberg MP, Miller JL, Hasan T. Cationic photoimmunoconjugates between monoclonal antibodies and hematoporphyrin: selective photodestruction of ovarian cancer cells. Appl Opt. 1998 Nov 1; 37(31):7184-92.
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  196. Soukos NS, Ximenez-Fyvie LA, Hamblin MR, Socransky SS, Hasan T. Targeted antimicrobial photochemotherapy. Antimicrob Agents Chemother. 1998 Oct; 42(10):2595-601.
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  197. Momma T, Hamblin MR, Hasan T. Hormonal modulation of the accumulation of 5-aminolevulinic acid-induced protoporphyrin and phototoxicity in prostate cancer cells. Int J Cancer. 1997 Sep 17; 72(6):1062-9.
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  198. Soukos NS, Hamblin MR, Hasan T. The effect of charge on cellular uptake and phototoxicity of polylysine chlorin(e6) conjugates. Photochem Photobiol. 1997 Apr; 65(4):723-9.
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  199. Duska LR, Hamblin MR, Bamberg MP, Hasan T. Biodistribution of charged F(ab')2 photoimmunoconjugates in a xenograft model of ovarian cancer. Br J Cancer. 1997; 75(6):837-44.
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  200. Hamblin MR, Miller JL, Hasan T. Effect of charge on the interaction of site-specific photoimmunoconjugates with human ovarian cancer cells. Cancer Res. 1996 Nov 15; 56(22):5205-10.
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  201. Molpus KL, Kato D, Hamblin MR, Lilge L, Bamberg M, Hasan T. Intraperitoneal photodynamic therapy of human epithelial ovarian carcinomatosis in a xenograft murine model. Cancer Res. 1996 Mar 1; 56(5):1075-82.
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  202. Hamblin MR, Newman EL. Photosensitizer targeting in photodynamic therapy. II. Conjugates of haematoporphyrin with serum lipoproteins. J Photochem Photobiol B. 1994 Nov; 26(2):147-57.
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  203. Hamblin MR, Newman EL. Photosensitizer targeting in photodynamic therapy. I. Conjugates of haematoporphyrin with albumin and transferrin. J Photochem Photobiol B. 1994 Oct; 26(1):45-56.
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  204. Hamblin MR, Newman EL. On the mechanism of the tumour-localising effect in photodynamic therapy. J Photochem Photobiol B. 1994 Apr; 23(1):3-8.
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  205. Hamblin M, Van Beek NA, Hughes PR, Wood HA. Co-occlusion and persistence of a baculovirus mutant lacking the polyhedrin gene. Appl Environ Microbiol. 1990 Oct; 56(10):3057-62.
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  206. Roth BL, Hamblin M, Ciaranello RD. Regulation of 5-HT2 and 5-HT1C serotonin receptor levels. Methodology and mechanisms. Neuropsychopharmacology. 1990 Oct-Dec; 3(5-6):427-33.
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  207. Hamblin MR, Flora JS, Potter BV. myo-Inositol phosphorothioates, phosphatase-resistant analogues of myo-inositol phosphates. Synthesis of DL-myo-inositol 1,4-bisphosphate and DL-myo-inositol 1,4-bisphosphorothioate. Biochem J. 1987 Sep 15; 246(3):771-4.
    View in: PubMed
  208. Hamblin MR, Cummins JH, Potter BV. Mung bean (Phaseolus aureus) nuclease. A mechanistic investigation of the DNA-cleavage reaction using a dinucleoside phosphorothioate. Biochem J. 1987 Feb 1; 241(3):827-33.
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  209. Hamblin MR, Potter BV. E. coli Ada regulatory protein repairs the SP diastereoisomer of alkylated DNA. FEBS Lett. 1985 Sep 23; 189(2):315-7.
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