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Last Name

Jorge Manuel Serrador, Ph.D.

TitleVisiting Associate Professor of Neurology
InstitutionBrigham and Women's Hospital
AddressBrigham and Womens Hospital
75 Francis St
Boston MA 02115

 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Falvo MJ, Serrador JM, McAndrew LM, Chandler HK, Lu SE, Quigley KS. A retrospective cohort study of U.S. service members returning from Afghanistan and Iraq: is physical health worsening over time? BMC Public Health. 2012; 12:1124.
    View in: PubMed
  2. Haack M, Serrador J, Cohen D, Simpson N, Meier-Ewert H, Mullington JM. Increasing sleep duration to lower beat-to-beat blood pressure: a pilot study. J Sleep Res. 2013 Jun; 22(3):295-304.
    View in: PubMed
  3. Corley GJ, Breen PP, Bîrlea SI, Serrador JM, Grace PA, Ólaighin G. Hemodynamic effects of habituation to a week-long program of neuromuscular electrical stimulation. Med Eng Phys. 2012 May; 34(4):459-65.
    View in: PubMed
  4. Nakagawa K, Serrador JM, LaRose SL, Sorond FA. Dynamic cerebral autoregulation after intracerebral hemorrhage: A case-control study. BMC Neurol. 2011; 11:108.
    View in: PubMed
  5. Sorond FA, Kiely DK, Galica A, Moscufo N, Serrador JM, Iloputaife I, Egorova S, Dell'Oglio E, Meier DS, Newton E, Milberg WP, Guttmann CR, Lipsitz LA. Neurovascular coupling is impaired in slow walkers: the MOBILIZE Boston Study. Ann Neurol. 2011 Aug; 70(2):213-20.
    View in: PubMed
  6. Deegan BM, Sorond FA, Galica A, Lipsitz LA, O'Laighin G, Serrador JM. Elderly women regulate brain blood flow better than men do. Stroke. 2011 Jul; 42(7):1988-93.
    View in: PubMed
  7. Mulavara AP, Fiedler MJ, Kofman IS, Wood SJ, Serrador JM, Peters B, Cohen HS, Reschke MF, Bloomberg JJ. Improving balance function using vestibular stochastic resonance: optimizing stimulus characteristics. Exp Brain Res. 2011 Apr; 210(2):303-12.
    View in: PubMed
  8. Deegan BM, Serrador JM, Nakagawa K, Jones E, Sorond FA, Olaighin G. The effect of blood pressure calibrations and transcranial Doppler signal loss on transfer function estimates of cerebral autoregulation. Med Eng Phys. 2011 Jun; 33(5):553-62.
    View in: PubMed
  9. Broderick BJ, Corley GJ, Quondamatteo F, Breen PP, Serrador J, Ólaighin G. Venous emptying from the foot: influences of weight bearing, toe curls, electrical stimulation, passive compression, and posture. J Appl Physiol. 2010 Oct; 109(4):1045-52.
    View in: PubMed
  10. Deegan BM, Devine ER, Geraghty MC, Jones E, Ólaighin G, Serrador JM. The relationship between cardiac output and dynamic cerebral autoregulation in humans. J Appl Physiol. 2010 Nov; 109(5):1424-31.
    View in: PubMed
  11. Sorond FA, Galica A, Serrador JM, Kiely DK, Iloputaife I, Cupples LA, Lipsitz LA. Cerebrovascular hemodynamics, gait, and falls in an elderly population: MOBILIZE Boston Study. Neurology. 2010 May 18; 74(20):1627-33.
    View in: PubMed
  12. Deegan BM, Cooke JP, Lyons D, Olaighin G, Serrador JM. Cerebral autoregulation in the vertebral and middle cerebral arteries during combine head upright tilt and lower body negative pressure in healthy humans. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:2505-8.
    View in: PubMed
  13. Serrador JM, Milberg WP. Cerebrovascular Hemodynamics and Cerebral Autoregulation in the Aging Brain. Cardiovascular Disease and the Brain: Considerations for the Development of Vascular Cognitive Impairment. 2010; in press.
  14. PP Breen, G O’Laighin, C McIntosh, S Dineen, JM Serrador. Enhancing sensory vibration perception using imperceptible electrical stimulation. Clinical Autonomic Research. 2009.
  15. BM Deegan, FA Sorond, LA Lipsitz, G O’Laighin, JM Serrador. The effects of sex and aging on cerebral blood flow regulation. Clinical Autonomic Research. 2009.
  16. Serrador JM, Schlegel TT, Black FO, Wood SJ. Vestibular effects on cerebral blood flow. BMC Neurosci. 2009; 10:119.
    View in: PubMed
  17. Serrador JM, Breen PP, ÓLaighin G, Deegan B, Geraghty M, Wood SJ. Enhancing Neural Signals with Stochastic Resonance Electrical Stimulation. Autonomic Neuroscience. 2009.
  18. Serrador JM, Lipsitz LA, Gopalakrishnan GS, Black FO, Wood SJ. Loss of otolith function with age is associated with increased postural sway measures. Neurosci Lett. 2009 Nov 6; 465(1):10-5.
    View in: PubMed
  19. Serrador JM, Lipsitz L, Black FO, Wood SJ . Decreases in Cerebral Blood Flow When Upright Are Related to Vestibular Function Regardless of Age. FASEB Journal. 2009; 23:613.35.
  20. Nakagawa K, Serrador JM, Larose SL, Moslehi F, Lipsitz LA, Sorond FA. Autoregulation in the posterior circulation is altered by the metabolic state of the visual cortex. Stroke. 2009 Jun; 40(6):2062-7.
    View in: PubMed
  21. Mullington JM, Haack M, Toth M, Serrador JM, Meier-Ewert HK. Cardiovascular, inflammatory, and metabolic consequences of sleep deprivation. Prog Cardiovasc Dis. 2009 Jan-Feb; 51(4):294-302.
    View in: PubMed
  22. Serrador JM, Toth M, Haack M, Sanchez A, Mullington JM. Sympathetic activation and cardiac response to 88 hours of wakefulness in healthy men and women. Sleep. 2009; 32:A162.
  23. Deegan BM, Sorond FA, Lipsitz LA, Olaighin G, Serrador JM. Gender related differences in cerebral autoregulation in older healthy subjects. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:2859-62.
    View in: PubMed
  24. Nakagawa K, Serrador JM, Sorond FA. Transfer Function Analysis of Dynamic Cerebral Autoregulation in Non-Traumatic Intracerebral Hemorrhage. Neurology. 2009; 72(11):A258.
  25. Haack M, Serrador J, Toth M, Cohen DA, Meier-Ewert H, Mullington JM. Improving sleep quantity decreases blood pressure in hypertensive patients. Sleep. 2009; 32:A331.
  26. Sorond FS, Serrador JM. Autoregulation in Ischemic Stroke. US Neurology. 2009; in press.
  27. Sorond FA, Serrador JM, Jones RN, Shaffer ML, Lipsitz LA. The sit-to-stand technique for the measurement of dynamic cerebral autoregulation. Ultrasound Med Biol. 2009 Jan; 35(1):21-9.
    View in: PubMed
  28. Deegan B, Geraghty MC, Hodgeman R, Reisner A, Serrador JM. Effect of Posture and Cardiac Output on Cerebral Autoregulation. FASEB Journal. 2008; 22:lb76.
  29. Sorond FA, Shnyer DM, Serrador JM, Milberg WP, Lipsitz LA. . Cerebral Blood Flow Regulation During Cognitive Tasks: Effects of Healthy Again. Cortex 2008 44: 179-84. 2008; 44:179-84.
  30. Sanchez A, Haack M, Toth M, Serrador J, Mullington J. Effects of sleep deprivation on blood pressure and vascular cellular adhesion molecules. Sleep. 2008; 31:A137.
  31. Toth M, Serrador J, Haack M, Gilmartin GS, Meier-Ewert HK, Mullington JM. Altered peripheral vascular reactivity in healthy adults during total sleep deprivation. Sleep. 2008; 31:A133.
  32. Deegan BM, Geraghty MC, Hodgeman RM, Reisner AA, O'Laighin G, Serrador JM. Assessment of techniques used to evaluate the effect of posture and cardiac output on cerebral autoregulation. Conf Proc IEEE Eng Med Biol Soc. 2008; 2008:1992-5.
    View in: PubMed
  33. Sorond FA, Schnyer DM, Serrador JM, Milberg WP, Lipsitz LA. Cerebral blood flow regulation during cognitive tasks: effects of healthy aging. Cortex. 2008 Feb; 44(2):179-84.
    View in: PubMed
  34. Serrador JM, Gopalakrishnan GS, Black FO, Lipsitz LA, Wood SJ. Effect of vestibular impairment on cerebral blood flow response to dynamic roll tilt. Clinical Autonomic Neuroscience. 2007.
  35. Gopalakrishnan GS, Baker E, Wood SJ, Serrador JM. Impaired Vestibular Function affects Orthostatic Cerebral Blood Flow Response. FASEB J. 2007; 21:A1383-4.
  36. Toth W, Serrador J, Haack W, Gilmartin G, Cohen D, Gopalakrishnan G, Meier-Ewert H, Mullington P. Peripheral vascular reactivity to forearm occlusion in healthy adults during total sleep deprivation. Sleep. 2007; 30:A142-3.
  37. Serrador JM, Gopalakrishnan GS, Pilowa AJ and Freeman R. Role of the Cholinergic System in Cerebral Blood Flow Response to Orthostatic Challenge. American Autonomic Society Meeting. 2006.
  38. Serrador JM, Gopalakrishnan GS, Baker E, Bayley G, Schlegel TT, Black FO and Wood SJ. Response of Respiration & CBF to Vestibular Stimulation. Barany Meeting, Uppsala, Sweden. 2006.
  39. Lipsitz LA, Iloputaife I, Gagnon M, Kiely DK, Serrador JM. Enhanced vasoreactivity and its response to antihypertensive therapy in hypertensive elderly women. Hypertension. 2006 Mar; 47(3):377-83.
    View in: PubMed
  40. Serrador JM, Hughson RL, Kowalchuk JM, Bondar RL, Gelb AW. Cerebral blood flow during orthostasis: role of arterial CO2. Am J Physiol Regul Integr Comp Physiol. 2006 Apr; 290(4):R1087-93.
    View in: PubMed
  41. Sorond FA, Khavari R, Serrador JM, Lipsitz LA. Regional cerebral autoregulation during orthostatic stress: age-related differences. J Gerontol A Biol Sci Med Sci. 2005 Nov; 60(11):1484-7.
    View in: PubMed
  42. Devine ER, Milberg WP, Serrador JM. Does gravity affect functional cerebral blood flow response?. International Cerebral Blood Flow Meeting, Amsterdam, The Netherlandss. 2005.
  43. Devine ER, Serrador JM. Relationship Between Stroke Volume And Cerebral Blood Flow During Pressure Changes in Humans. XXXV International Congress of Phsyiological Sciences, San Diego, CA. 2005.
  44. Serrador JM, Schlegel TT, Black FO, Wood SJ. Cerebral hypoperfusion precedes nausea during centrifugation. Aviat Space Environ Med. 2005 Feb; 76(2):91-6.
    View in: PubMed
  45. Lipsitz LA, Gagnon M, Vyas M, Iloputaife I, Kiely DK, Sorond F, Serrador J, Cheng DM, Babikian V, Cupples LA. Antihypertensive therapy increases cerebral blood flow and carotid distensibility in hypertensive elderly subjects. Hypertension. 2005 Feb; 45(2):216-21.
    View in: PubMed
  46. Serrador JM, Wood SJ. Neurohumoral Link Between Nausea and Motion Sickness: A response. Aviation, Space, and Environmental Medicine. 2005; 76(8):805-806.
  47. Serrador JM, Sorond FA, Vyas M, Gagnon M, Iloputaife ID, Lipsitz LA. Cerebral pressure-flow relations in hypertensive elderly humans: transfer gain in different frequency domains. J Appl Physiol. 2005 Jan; 98(1):151-9.
    View in: PubMed
  48. Serrador JM, Milberg WP, Lipsitz LA. Cerebral Hemodynamics in the Elderly. Paul RH, Cohen RA, Ott BR and Salloway S, editors. Vascular Dementia: Cerebrovascular Mechanims and Clinical Management. 2004; 75-86.
  49. Wood SJ, Serrador JM, Black FO, Rupert AH, Schlegel TT. Effects of vestibular loss on orthostatic responses to tilts in the pitch plane. Assoc Res Otolaryngol. 2004; Abs 64.
  50. Broussard J, Haack M, Serrador J, Mullington JM. Effects of sleep restriction on blood pressure. Sleep. 2004; 27(375 Suppl. S):171.
  51. Kimmerly DS, Tutungi E, Wilson TD, Serrador JM, Gelb AW, Hughson RL, Shoemaker JK. Circulating norepinephrine and cerebrovascular control in conscious humans. Clin Physiol Funct Imaging. 2003 Nov; 23(6):314-9.
    View in: PubMed
  52. Wilson TD, Serrador JM, Shoemaker JK. Head position modifies cerebrovascular response to orthostatic stress. Brain Res. 2003 Jan 31; 961(2):261-8.
    View in: PubMed
  53. Serrador JM, Schlegel TT, Black FO, Wood SJ. Cerebral blood flow response to vestibular stimulation. Clin Auton Res. 2003; 13(5):391.
  54. Serrador JM, Schlegel TT, Black FO, Wood SJ. Vestibular-Cerebrovascular Interactions During Upright Tilt. FASEB J. 2003; 17(4):A20.
  55. Serrador JM, Hunt BE, Beske SD, Kaushal P, Taylor JA. Autonomic control of cerebral circulation. FASEB J. 2002; 16(5):A1125.
  56. Serrador JM, Wood SJ, Wilson TD, Schlegel TT. Role of vestibular system in cerebrovascular response to parabolic flight. J Vestib Res. 2002; 11(3-4):331-332.
  57. Serrador JM, Wood SJ, Black FO, Schlegel TT. Cerebrovascular response to tilts in the pitch and roll planes. J Vestib Res. 2002; 11(3-4):218-219.
  58. Serrador JM, Wood SJ, Picot PA, Stein F, Kassam MS, Bondar RL, Rupert AH, Schlegel TT. Effect of acute exposure to hypergravity (GX vs. GZ) on dynamic cerebral autoregulation. J Appl Physiol. 2001 Nov; 91(5):1986-94.
    View in: PubMed
  59. Blaber AP, Bondar RL, Moradshahi P, Serrador JM, Hughson RL. Inspiratory CO2 increases orthostatic tolerance during repeated tilt. Aviat Space Environ Med. 2001 Nov; 72(11):985-91.
    View in: PubMed
  60. Houtman S, Serrador JM, Colier WN, Strijbos DW, Shoemaker K, Hopman MT. Changes in cerebral oxygenation and blood flow during LBNP in spinal cord-injured individuals. J Appl Physiol. 2001 Nov; 91(5):2199-204.
    View in: PubMed
  61. Serrador JM and Taylor JA. Cerebral Autoregulation: new insights into assessment. Proceedings of the XXXIV International Union of Physiological Sciences Congress. 2001.
  62. Tutungi E, Wilson TD, Serrador JM, Tulppo M, Gelb AW, Shoemaker JK. Effects of noradrenaline and phentolamine on cerebral vasculature in conscious, healthy individuals. Anaesth Intensive Care. 2001; 29(1):77.
  63. Serrador JM, Shoemaker JK, Brown TE, Kassam MS, Bondar RL, Schlegel TT. Cerebral vasoconstriction precedes orthostatic intolerance after parabolic flight. Brain Res Bull. 2000 Sep 1; 53(1):113-20.
    View in: PubMed
  64. Serrador JM, Picot PA, Rutt BK, Shoemaker JK, Bondar RL. MRI measures of middle cerebral artery diameter in conscious humans during simulated orthostasis. Stroke. 2000 Jul; 31(7):1672-8.
    View in: PubMed
  65. Serrador JM, Shoemaker JK, Kowalchuk JM, Hughson RL, Bondar RL, Gelb AW. Hyperventilation does not induce a paradoxical cerebral vasoconstriction during head up tilt. Physiologist. 2000; 43(4):329.
  66. Serrador JM. Cerebral autoregulation during orthostatic stress. 2000.
  67. Serrador JM, Houtman S, Shoemaker JK, Hopman MTE. Cerebrovascular regulation differs in the ACA and MCA territories during orthostatic stress in spinal cord injured patients. FASEB J. 2000; 14(4):A428.
  68. Serrador JM, Finlayson HC, Hughson RL. Physical activity is a major contributor to the ultra low frequency components of heart rate variability. Heart. 1999 Dec; 82(6):e9.
    View in: PubMed
  69. Serrador JM. Space & Altitude Physiology. 1999.
  70. Serrador JM, Chambers MG, Brock RW, Hawley JA, Bondar RL, Hughson RL. Role of previous simulated G-force exposure and AGSM on tolerance to orthostatic stress (LBNP). FASEB J. 1998; 11(3):A96.
  71. Serrador JM, Bondar RL, Hughson RL. Ventilatory response to passive head up tilt. Adv Exp Med Biol. 1998; 450:133-9.
    View in: PubMed
  72. Serrador JM, Irving S, Picot PA, Kowalchuk JM, Bondar RL. Cerebral blood flow changes during a ramped exercise test to exhaustion. Med Sci Sports Exerc. 1998; 30(5):S104.
  73. Serrador JM. Repeated short duration Gz force exposure affects acute response to orthostatic stress. 1997.
  74. Hughson RL, Serrador JM, Stronach J, Lin DC, Golnaraghi MF, Yamamoto Y. 24 hour heart rate and EMG monitoring during rest and normal daily activity. Med Sci Sports Exerc. 1997; 29(5):S178.
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