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Zane R. Hollingsworth, M.P.H.

TitleInstructor in Neurology
InstitutionMassachusetts General Hospital
DepartmentNeurology
AddressMassachusetts General Hospital
B114 - 2001
114 16th Street
Charlestown MA 02129
Phone617/726-5563
Fax617/724-1480

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Cantuti-Castelvetri I, Hernandez LF, Keller-McGandy CE, Kett LR, Landy A, Hollingsworth ZR, Saka E, Crittenden JR, Nillni EA, Young AB, Standaert DG, Graybiel AM. Levodopa-induced dyskinesia is associated with increased thyrotropin releasing hormone in the dorsal striatum of hemi-parkinsonian rats. PLoS One. 2010; 5(11):e13861.
    View in: PubMed
  2. Coufal M, Maxwell MM, Russel DE, Amore AM, Altmann SM, Hollingsworth ZR, Young AB, Housman DE, Kazantsev AG. Discovery of a novel small-molecule targeting selective clearance of mutant huntingtin fragments. J Biomol Screen. 2007 Apr; 12(3):351-60.
    View in: PubMed
  3. Hodges A, Strand AD, Aragaki AK, Kuhn A, Sengstag T, Hughes G, Elliston LA, Hartog C, Goldstein DR, Thu D, Hollingsworth ZR, Collin F, Synek B, Holmans PA, Young AB, Wexler NS, Delorenzi M, Kooperberg C, Augood SJ, Faull RL, Olson JM, Jones L, Luthi-Carter R. Regional and cellular gene expression changes in human Huntington's disease brain. Hum Mol Genet. 2006 Mar 15; 15(6):965-77.
    View in: PubMed
  4. Miller DW, Johnson JM, Solano SM, Hollingsworth ZR, Standaert DG, Young AB. Absence of alpha-synuclein mRNA expression in normal and multiple system atrophy oligodendroglia. J Neural Transm. 2005 Dec; 112(12):1613-24.
    View in: PubMed
  5. Wexler NS, Lorimer J, Porter J, Gomez F, Moskowitz C, Shackell E, Marder K, Penchaszadeh G, Roberts SA, Gayán J, Brocklebank D, Cherny SS, Cardon LR, Gray J, Dlouhy SR, Wiktorski S, Hodes ME, Conneally PM, Penney JB, Gusella J, Cha JH, Irizarry M, Rosas D, Hersch S, Hollingsworth Z, MacDonald M, Young AB, Andresen JM, Housman DE, De Young MM, Bonilla E, Stillings T, Negrette A, Snodgrass SR, Martinez-Jaurrieta MD, Ramos-Arroyo MA, Bickham J, Ramos JS, Marshall F, Shoulson I, Rey GJ, Feigin A, Arnheim N, Acevedo-Cruz A, Acosta L, Alvir J, Fischbeck K, Thompson LM, Young A, Dure L, O'Brien CJ, Paulsen J, Brickman A, Krch D, Peery S, Hogarth P, Higgins DS, Landwehrmeyer B. Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset. Proc Natl Acad Sci U S A. 2004 Mar 9; 101(10):3498-503.
    View in: PubMed
  6. Augood SJ, Hollingsworth Z, Albers DS, Yang L, Leung J, Breakefield XO, Standaert DG. Dopamine transmission in DYT1 dystonia. Adv Neurol. 2004; 94:53-60.
    View in: PubMed
  7. Augood SJ, Hollingsworth Z, Albers DS, Yang L, Leung JC, Muller B, Klein C, Breakefield XO, Standaert DG. Dopamine transmission in DYT1 dystonia: a biochemical and autoradiographical study. Neurology. 2002 Aug 13; 59(3):445-8.
    View in: PubMed
  8. Spektor BS, Miller DW, Hollingsworth ZR, Kaneko YA, Solano SM, Johnson JM, Penney JB, Young AB, Luthi-Carter R. Differential D1 and D2 receptor-mediated effects on immediate early gene induction in a transgenic mouse model of Huntington's disease. Brain Res Mol Brain Res. 2002 Jun 15; 102(1-2):118-28.
    View in: PubMed
  9. Augood SJ, Hollingsworth ZR, Standaert DG, Emson PC, Penney JB. Localization of dopaminergic markers in the human subthalamic nucleus. J Comp Neurol. 2000 May 29; 421(2):247-55.
    View in: PubMed
  10. Luthi-Carter R, Strand A, Peters NL, Solano SM, Hollingsworth ZR, Menon AS, Frey AS, Spektor BS, Penney EB, Schilling G, Ross CA, Borchelt DR, Tapscott SJ, Young AB, Cha JH, Olson JM. Decreased expression of striatal signaling genes in a mouse model of Huntington's disease. Hum Mol Genet. 2000 May 22; 9(9):1259-71.
    View in: PubMed
  11. Testa CM, Hollingsworth ZR, Shinozaki H, Penney JB, Young AB. Selective metabotropic receptor agonists distinguish non-ionotropic glutamate binding sites. Brain Res. 1997 Oct 31; 773(1-2):15-27.
    View in: PubMed
  12. Scherzer CR, Landwehrmeyer GB, Kerner JA, Standaert DG, Hollingsworth ZR, Daggett LP, Veliçelebi G, Penney JB, Young AB. Cellular distribution of NMDA glutamate receptor subunit mRNAs in the human cerebellum. Neurobiol Dis. 1997; 4(1):35-46.
    View in: PubMed
  13. Standaert DG, Testa CM, Rudolf GD, Hollingsworth ZR. Inhibition of N-methyl-D-aspartate glutamate receptor subunit expression by antisense oligonucleotides reveals their role in striatal motor regulation. J Pharmacol Exp Ther. 1996 Jan; 276(1):342-52.
    View in: PubMed
  14. Giordani B, Berent S, Boivin MJ, Penney JB, Lehtinen S, Markel DS, Hollingsworth Z, Butterbaugh G, Hichwa RD, Gusella JF, et al. Longitudinal neuropsychological and genetic linkage analysis of persons at risk for Huntington's disease. Arch Neurol. 1995 Jan; 52(1):59-64.
    View in: PubMed
  15. Aldrich MS, Prokopowicz G, Ockert K, Hollingsworth Z, Penney JB, Albin RL. Neurochemical studies of human narcolepsy: alpha-adrenergic receptor autoradiography of human narcoleptic brain and brainstem. Sleep. 1994 Oct; 17(7):598-608.
    View in: PubMed
  16. Arregui A, Hollingsworth Z, Penney JB, Young AB. Autoradiographic evidence for increased dopamine uptake sites in striatum of hypoxic mice. Neurosci Lett. 1994 Feb 14; 167(1-2):195-7.
    View in: PubMed
  17. Catania MV, Hollingsworth Z, Penney JB, Young AB. Quisqualate resolves two distinct metabotropic [3H]glutamate binding sites. Neuroreport. 1993 Mar; 4(3):311-3.
    View in: PubMed
  18. Albin RL, Hollingsworth Z, Sakurai SY, Gilman S. Inhibitory and excitatory amino acid neurotransmitter binding sites in cynomolgus monkey (Macaca fascicularis) cervical spinal cord. Brain Res. 1993 Feb 26; 604(1-2):354-7.
    View in: PubMed
  19. Price RH, Hollingsworth Z, Young AB, Penney JB. Excitatory amino acid receptor regulation after subthalamic nucleus lesions in the rat. Brain Res. 1993 Jan 29; 602(1):157-60.
    View in: PubMed
  20. Catania MV, Hollingsworth Z, Penney JB, Young AB. Phospholipase A2 modulates different subtypes of excitatory amino acid receptors: autoradiographic evidence. J Neurochem. 1993 Jan; 60(1):236-45.
    View in: PubMed
  21. Aldrich MS, Hollingsworth Z, Penney JB. Autoradiographic studies of post-mortem human narcoleptic brain. Neurophysiol Clin. 1993 Jan; 23(1):35-45.
    View in: PubMed
  22. Difazio MC, Hollingsworth Z, Young AB, Penney JB. Glutamate receptors in the substantia nigra of Parkinson's disease brains. Neurology. 1992 Feb; 42(2):402-6.
    View in: PubMed
  23. Aldrich MS, Hollingsworth Z, Penney JB. Dopamine-receptor autoradiography of human narcoleptic brain. Neurology. 1992 Feb; 42(2):410-5.
    View in: PubMed
  24. Albin RL, Makowiec RL, Hollingsworth ZR, Dure LS, Penney JB, Young AB. Excitatory amino acid binding sites in the basal ganglia of the rat: a quantitative autoradiographic study. Neuroscience. 1992; 46(1):35-48.
    View in: PubMed
  25. Young AB, Dauth GW, Hollingsworth Z, Penney JB, Kaatz K, Gilman S. Quisqualate- and NMDA-sensitive [3H]glutamate binding in primate brain. J Neurosci Res. 1990 Dec; 27(4):512-21.
    View in: PubMed
  26. Albin RL, Makowiec RL, Hollingsworth Z, Dure LS, Penney JB, Young AB. Excitatory amino acid binding sites in the periaqueductal gray of the rat. Neurosci Lett. 1990 Oct 2; 118(1):112-5.
    View in: PubMed
  27. Penney JB, Maragos WF, Greenamyre JT, Debowey DL, Hollingsworth Z, Young AB. Excitatory amino acid binding sites in the hippocampal region of Alzheimer's disease and other dementias. J Neurol Neurosurg Psychiatry. 1990 Apr; 53(4):314-20.
    View in: PubMed
  28. Cha JH, Hollingsworth ZR, Greenamyre JT, Young AB. Contamination of commercially available quisqualic acid by glutamate-like and aspartate-like substances. J Neurosci Methods. 1989 Mar; 27(2):143-8.
    View in: PubMed
  29. Young AB, Greenamyre JT, Hollingsworth Z, Albin R, D'Amato C, Shoulson I, Penney JB. NMDA receptor losses in putamen from patients with Huntington's disease. Science. 1988 Aug 19; 241(4868):981-3.
    View in: PubMed
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