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Ming-Chieh Michelle Shun, Ph.D.

TitleResearch Fellow in Pathology (EXT)
InstitutionDana-Farber Cancer Institute
DepartmentPathology
AddressDana Farber Cancer Institute
Jimmy Fund Bldg, 621
44 Binney St
Boston MA 02115
Phone617/632-4360
Fax617/632-3113

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Wang H, Jurado KA, Wu X, Shun MC, Li X, Ferris AL, Smith SJ, Patel PA, Fuchs JR, Cherepanov P, Kvaratskhelia M, Hughes SH, Engelman A. HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor. Nucleic Acids Res. 2012 Dec; 40(22):11518-30.
    View in: PubMed
  2. Shun MC, Yu W, Park SK, Sanders BG, Kline K. Downregulation of Epidermal Growth Factor Receptor Expression Contributes to alpha-TEA's Proapoptotic Effects in Human Ovarian Cancer Cell Lines. J Oncol. 2010; 2010:824571.
    View in: PubMed
  3. Ferris AL, Wu X, Hughes CM, Stewart C, Smith SJ, Milne TA, Wang GG, Shun MC, Allis CD, Engelman A, Hughes SH. Lens epithelium-derived growth factor fusion proteins redirect HIV-1 DNA integration. Proc Natl Acad Sci U S A. 2010 Feb 16; 107(7):3135-40.
    View in: PubMed
  4. Dar MJ, Monel B, Krishnan L, Shun MC, Di Nunzio F, Helland DE, Engelman A. Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase. Retrovirology. 2009; 6:94.
    View in: PubMed
  5. Hare S, Shun MC, Gupta SS, Valkov E, Engelman A, Cherepanov P. A novel co-crystal structure affords the design of gain-of-function lentiviral integrase mutants in the presence of modified PSIP1/LEDGF/p75. PLoS Pathog. 2009 Jan; 5(1):e1000259.
    View in: PubMed
  6. Shun MC, Botbol Y, Li X, Di Nunzio F, Daigle JE, Yan N, Lieberman J, Lavigne M, Engelman A. Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity. J Virol. 2008 Dec; 82(23):11555-67.
    View in: PubMed
  7. Shun MC, Raghavendra NK, Vandegraaff N, Daigle JE, Hughes S, Kellam P, Cherepanov P, Engelman A. LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration. Genes Dev. 2007 Jul 15; 21(14):1767-78.
    View in: PubMed
  8. Shun MC, Daigle JE, Vandegraaff N, Engelman A. Wild-type levels of human immunodeficiency virus type 1 infectivity in the absence of cellular emerin protein. J Virol. 2007 Jan; 81(1):166-72.
    View in: PubMed
  9. Yu W, Shun MC, Anderson K, Chen H, Sanders BG, Kline K. alpha-TEA inhibits survival and enhances death pathways in cisplatin sensitive and resistant human ovarian cancer cells. Apoptosis. 2006 Oct; 11(10):1813-23.
    View in: PubMed
  10. Shun MC, Yu W, Gapor A, Parsons R, Atkinson J, Sanders BG, Kline K. Pro-apoptotic mechanisms of action of a novel vitamin E analog (alpha-TEA) and a naturally occurring form of vitamin E (delta-tocotrienol) in MDA-MB-435 human breast cancer cells. Nutr Cancer. 2004; 48(1):95-105.
    View in: PubMed
  11. Ning JP, Ouyang C, Shun M. [Two cases of diuretic abuse]. Hunan Yi Ke Da Xue Xue Bao. 2003 Jun; 28(3):258, 277.
    View in: PubMed
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