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Tatjana Claudia Jakobs, M.D.

TitleAssistant Professor of Ophthalmology
InstitutionMassachusetts Eye and Ear Infirmary
DepartmentOphthalmology
AddressSchepens Eye Research Institute
20 Staniford Street
Boston MA 02114
Phone6179120205
Fax617/726-5336

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Sun D, Qu J, Jakobs TC. Reversible reactivity by optic nerve astrocytes. Glia. 2013 Aug; 61(8):1218-35.
    View in: PubMed
  2. Lye-Barthel M, Sun D, Jakobs TC. Morphology of astrocytes in a glaucomatous optic nerve. Invest Ophthalmol Vis Sci. 2013; 54(2):909-17.
    View in: PubMed
  3. Sun D, Jakobs TC. Structural remodeling of astrocytes in the injured CNS. Neuroscientist. 2012 Dec; 18(6):567-88.
    View in: PubMed
  4. Koizumi A, Jakobs TC, Masland RH. Regular mosaic of synaptic contacts among three retinal neurons. J Comp Neurol. 2011 Feb 1; 519(2):341-57.
    View in: PubMed
  5. Sun D, Lye-Barthel M, Masland RH, Jakobs TC. Structural remodeling of fibrous astrocytes after axonal injury. J Neurosci. 2010 Oct 20; 30(42):14008-19.
    View in: PubMed
  6. Sun D, Lye-Barthel M, Masland RH, Jakobs TC. The morphology and spatial arrangement of astrocytes in the optic nerve head of the mouse. J Comp Neurol. 2009 Sep 1; 516(1):1-19.
    View in: PubMed
  7. Jakobs TC, Koizumi A, Masland RH. The spatial distribution of glutamatergic inputs to dendrites of retinal ganglion cells. J Comp Neurol. 2008 Sep 10; 510(2):221-36.
    View in: PubMed
  8. Howell GR, Libby RT, Jakobs TC, Smith RS, Phalan FC, Barter JW, Barbay JM, Marchant JK, Mahesh N, Porciatti V, Whitmore AV, Masland RH, John SW. Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma. J Cell Biol. 2007 Dec 31; 179(7):1523-37.
    View in: PubMed
  9. Jakobs TC, Ben Y, Masland RH. Expression of mRNA for glutamate receptor subunits distinguishes the major classes of retinal neurons, but is less specific for individual cell types. Mol Vis. 2007; 13:933-48.
    View in: PubMed
  10. Lye MH, Jakobs TC, Masland RH, Koizumi A. Organotypic culture of adult rabbit retina. J Vis Exp. 2007; (3):190.
    View in: PubMed
  11. Koizumi A, Zeck G, Ben Y, Masland RH, Jakobs TC. Organotypic culture of physiologically functional adult mammalian retinas. PLoS One. 2007; 2(2):e221.
    View in: PubMed
  12. Enoki R, Jakobs TC, Koizumi A. Horizontal slice preparation of the retina. J Vis Exp. 2006 Dec; (1):108.
    View in: PubMed
  13. Jakobs TC, Libby RT, Ben Y, John SW, Masland RH. Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J mice. J Cell Biol. 2005 Oct 24; 171(2):313-25.
    View in: PubMed
  14. Lin B, Jakobs TC, Masland RH. Different functional types of bipolar cells use different gap-junctional proteins. J Neurosci. 2005 Jul 13; 25(28):6696-701.
    View in: PubMed
  15. Koizumi A, Jakobs TC, Masland RH. Inward rectifying currents stabilize the membrane potential in dendrites of mouse amacrine cells: patch-clamp recordings and single-cell RT-PCR. Mol Vis. 2004 May 13; 10:328-40.
    View in: PubMed
  16. Jakobs TC, Ben Y, Masland RH. CD15 immunoreactive amacrine cells in the mouse retina. J Comp Neurol. 2003 Oct 20; 465(3):361-71.
    View in: PubMed
  17. Sugawara H, Egashira M, Harada N, Jakobs TC, Yoshiura K, Kishino T, Ohta T, Niikawa N, Matsumoto N. Breakpoint analysis of a familial balanced translocation t(2;8)(q31;p21) associated with mesomelic dysplasia. J Med Genet. 2002 Jul; 39(7):E34.
    View in: PubMed
  18. Jakobs TC, Mentrup B, Schmutzler C, Dreher I, Köhrle J. Proinflammatory cytokines inhibit the expression and function of human type I 5'-deiodinase in HepG2 hepatocarcinoma cells. Eur J Endocrinol. 2002 Apr; 146(4):559-66.
    View in: PubMed
  19. Winzer R, Schmutzler C, Jakobs TC, Ebert R, Rendl J, Reiners C, Jakob F, Köhrle J. Reverse transcriptase-polymerase chain reaction analysis of thyrocyte-relevant genes in fine-needle aspiration biopsies of the human thyroid. Thyroid. 1998 Nov; 8(11):981-7.
    View in: PubMed
  20. schmutzler C, Brtko J, Winzer R, Jakobs TC, Meissner-Weigl J, Simon D, Goretzki PE, Köhrle J. Functional retinoid and thyroid hormone receptors in human thyroid-carcinoma cell lines and tissues. Int J Cancer. 1998 May 4; 76(3):368-76.
    View in: PubMed
  21. Dreher I, Jakobs TC, Köhrle J. Cloning and characterization of the human selenoprotein P promoter. Response of selenoprotein P expression to cytokines in liver cells. J Biol Chem. 1997 Nov 14; 272(46):29364-71.
    View in: PubMed
  22. Jakobs TC, Schmutzler C, Meissner J, Köhrle J. The promoter of the human type I 5'-deiodinase gene--mapping of the transcription start site and identification of a DR+4 thyroid-hormone-responsive element. Eur J Biochem. 1997 Jul 1; 247(1):288-97.
    View in: PubMed
  23. Jakobs TC, Koehler MR, Schmutzler C, Glaser F, Schmid M, Köhrle J. Structure of the human type I iodothyronine 5'-deiodinase gene and localization to chromosome 1p32-p33. Genomics. 1997 Jun 1; 42(2):361-3.
    View in: PubMed
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