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Keywords
Last Name
Institution

Umar Mahmood, M.D., PH.D.

TitleAssociate Professor of Radiology
InstitutionMassachusetts General Hospital
DepartmentRadiology
AddressMassachusetts General Hospital
Nuclear Medicine/Radiology White 427
55 Fruit St
Boston MA 02114
Phone617/726-6477
Fax617/726-6165

 Mentoring 
 completed student projects
A Real-Time Method for Quantitative Catheter-Based Fluorescence Molecular Imaging
Summer, 06/01/05 - 09/01/05

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Sheth RA, Heidari P, Esfahani SA, Wood BJ, Mahmood U. Interventional Optical Molecular Imaging Guidance during Percutaneous Biopsy. Radiology. 2014 Feb 8; 131880.
    View in: PubMed
  2. Zadra G, Photopoulos C, Tyekucheva S, Heidari P, Weng QP, Fedele G, Liu H, Scaglia N, Priolo C, Sicinska E, Mahmood U, Signoretti S, Birnberg N, Loda M. A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis. EMBO Mol Med. 2014 Feb 4.
    View in: PubMed
  3. Heidari P, Wehrenberg-Klee E, Habibollahi P, Yokell D, Kulke M, Mahmood U. Free somatostatin receptor fraction predicts the antiproliferative effect of octreotide in a neuroendocrine tumor model: implications for dose optimization. Cancer Res. 2013 Dec 1; 73(23):6865-73.
    View in: PubMed
  4. Martinez-Quintanilla J, Bhere D, Heidari P, He D, Mahmood U, Shah K. Therapeutic efficacy and fate of bimodal engineered stem cells in malignant brain tumors. Stem Cells. 2013 Aug; 31(8):1706-14.
    View in: PubMed
  5. Kucherlapati MH, Esfahani S, Habibollahi P, Wang J, Still ER, Bronson RT, Mahmood U, Kucherlapati RS. Genotype directed therapy in murine mismatch repair deficient tumors. PLoS One. 2013; 8(7):e68817.
    View in: PubMed
  6. Leece AK, Heidari P, Yokell DL, Mahmood U. A container closure system that allows for greater recovery of radiolabeled peptide compared to the standard borosilicate glass system. Appl Radiat Isot. 2013 Oct; 80:99-102.
    View in: PubMed
  7. Esfahani SA, Heidari P, Halpern EF, Hochberg EP, Palmer EL, Mahmood U. Baseline total lesion glycolysis measured with (18)F-FDG PET/CT as a predictor of progression-free survival in diffuse large B-cell lymphoma: a pilot study. Am J Nucl Med Mol Imaging. 2013; 3(3):272-81.
    View in: PubMed
  8. Martin ES, Belmont PJ, Sinnamon MJ, Richard LG, Yuan J, Coffee EM, Roper J, Lee L, Heidari P, Lunt SY, Goel G, Ji X, Xie Z, Xie T, Lamb J, Weinrich SL, Vanarsdale T, Bronson RT, Xavier RJ, Vander Heiden MG, Kan JL, Mahmood U, Hung KE. Development of a Colon Cancer GEMM-Derived Orthotopic Transplant Model for Drug Discovery and Validation. Clin Cancer Res. 2013 Jun 1; 19(11):2929-40.
    View in: PubMed
  9. Cho H, Alcantara D, Yuan H, Sheth RA, Chen HH, Huang P, Andersson SB, Sosnovik DE, Mahmood U, Josephson L. Fluorochrome-functionalized nanoparticles for imaging DNA in biological systems. ACS Nano. 2013 Mar 26; 7(3):2032-41.
    View in: PubMed
  10. Habibollahi P, van den Berg NS, Kuruppu D, Loda M, Mahmood U. Metformin--an Adjunct Antineoplastic Therapy--Divergently Modulates Tumor Metabolism and Proliferation, Interfering with Early Response Prediction by 18F-FDG PET Imaging. J Nucl Med. 2013 Feb; 54(2):252-8.
    View in: PubMed
  11. Wong GS, Habibollahi P, Heidari P, Lee JS, Klein-Szanto AJ, Waldron TJ, Gimotty P, Nakagawa H, Taylor PR, Wang TC, Mahmood U, Rustgi AK. Optical imaging of periostin enables early endoscopic detection and characterization of esophageal cancer in mice. Gastroenterology. 2013 Feb; 144(2):294-7.
    View in: PubMed
  12. Saylor PJ, Mahmood U, Kunawudhi A, Smith MR, Palmer EL, Michaelson MD. Multitargeted Tyrosine Kinase Inhibition Produces Discordant Changes Between 99mTc-MDP Bone Scans and Other Disease Biomarkers: Analysis of a Phase II Study of Sunitinib for Metastatic Castration-Resistant Prostate Cancer. J Nucl Med. 2012 Nov; 53(11):1670-5.
    View in: PubMed
  13. Sheth RA, Kunin A, Stangenberg L, Sinnamon M, Hung KE, Kucherlapati R, Mahmood U. In vivo optical molecular imaging of matrix metalloproteinase activity following celecoxib therapy for colorectal cancer. Mol Imaging. 2012 Sep-Oct; 11(5):417-25.
    View in: PubMed
  14. Yokell DL, Leece AK, Lebedev A, Miraghaie R, Ball CE, Zhang J, Kolb H, Elizarov A, Mahmood U. Microfluidic single vessel production of hypoxia tracer 1H-1-(3-[18F]-fluoro-2-hydroxy-propyl)-2-nitro-imidazole ([18F]-FMISO). Appl Radiat Isot. 2012 Oct; 70(10):2313-6.
    View in: PubMed
  15. Habibollahi P, Figueiredo JL, Heidari P, Dulak AM, Imamura Y, Bass AJ, Ogino S, Chan AT, Mahmood U. Optical Imaging with a Cathepsin B Activated Probe for the Enhanced Detection of Esophageal Adenocarcinoma by Dual Channel Fluorescent Upper GI Endoscopy. Theranostics. 2012; 2(2):227-34.
    View in: PubMed
  16. Quante M, Bhagat G, Abrams JA, Marache F, Good P, Lee MD, Lee Y, Friedman R, Asfaha S, Dubeykovskaya Z, Mahmood U, Figueiredo JL, Kitajewski J, Shawber C, Lightdale CJ, Rustgi AK, Wang TC. Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia. Cancer Cell. 2012 Jan 17; 21(1):36-51.
    View in: PubMed
  17. Scope A, Mahmood U, Gareau DS, Kenkre M, Lieb JA, Nehal KS, Rajadhyaksha M. In vivo reflectance confocal microscopy of shave biopsy wounds: feasibility of intraoperative mapping of cancer margins. Br J Dermatol. 2010 Dec; 163(6):1218-28.
    View in: PubMed
  18. Chan AT, Baba Y, Shima K, Nosho K, Chung DC, Hung KE, Mahmood U, Madden K, Poss K, Ranieri A, Shue D, Kucherlapati R, Fuchs CS, Ogino S. Cathepsin B expression and survival in colon cancer: implications for molecular detection of neoplasia. Cancer Epidemiol Biomarkers Prev. 2010 Nov; 19(11):2777-85.
    View in: PubMed
  19. Sheth RA, Mahmood U. Optical molecular imaging and its emerging role in colorectal cancer. Am J Physiol Gastrointest Liver Physiol. 2010 Oct; 299(4):G807-20.
    View in: PubMed
  20. Sheth RA, Maricevich M, Mahmood U. In vivo optical molecular imaging of matrix metalloproteinase activity in abdominal aortic aneurysms correlates with treatment effects on growth rate. Atherosclerosis. 2010 Sep; 212(1):181-7.
    View in: PubMed
  21. Mahmood U. Science to practice: can a targeted nanoparticle be used to image autoimmune nephritis? Radiology. 2010 May; 255(2):309-10.
    View in: PubMed
  22. Hung KE, Maricevich MA, Richard LG, Chen WY, Richardson MP, Kunin A, Bronson RT, Mahmood U, Kucherlapati R. Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment. Proc Natl Acad Sci U S A. 2010 Jan 26; 107(4):1565-70.
    View in: PubMed
  23. Ventura E, Islam T, Gee MS, Mahmood U, Braschi M, Harisinghani MG. Detection of nodal metastatic disease in patients with non-small cell lung cancer: comparison of positron emission tomography (PET), contrast-enhanced computed tomography (CT), and combined PET-CT. Clin Imaging. 2010 Jan-Feb; 34(1):20-8.
    View in: PubMed
  24. Mahmood U. Optical molecular imaging approaches in colorectal cancer. Gastroenterology. 2010 Feb; 138(2):419-22.
    View in: PubMed
  25. Sheth RA, Josephson L, Mahmood U. Evaluation and clinically relevant applications of a fluorescent imaging analog to fluorodeoxyglucose positron emission tomography. J Biomed Opt. 2009 Nov-Dec; 14(6):064014.
    View in: PubMed
  26. Wadlow RC, Wittner BS, Finley SA, Bergquist H, Upadhyay R, Finn S, Loda M, Mahmood U, Ramaswamy S. Systems-level modeling of cancer-fibroblast interaction. PLoS One. 2009; 4(9):e6888.
    View in: PubMed
  27. Mahmood U. Science to practice: can an enzyme-sensitive MR contrast agent be used to image inflammation in aneurysms? Radiology. 2009 Sep; 252(3):627-8.
    View in: PubMed
  28. Stangenberg L, Ellson C, Cortez-Retamozo V, Ortiz-Lopez A, Yuan H, Blois J, Smith RA, Yaffe MB, Weissleder R, Benoist C, Mathis D, Josephson L, Mahmood U. Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function. Arthritis Rheum. 2009 Aug; 60(8):2314-24.
    View in: PubMed
  29. Yoon SS, Stangenberg L, Lee YJ, Rothrock C, Dreyfuss JM, Baek KH, Waterman PR, Nielsen GP, Weissleder R, Mahmood U, Park PJ, Jacks T, Dodd RD, Fisher CJ, Ryeom S, Kirsch DG. Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma. Int J Radiat Oncol Biol Phys. 2009 Jul 15; 74(4):1207-16.
    View in: PubMed
  30. Hilderbrand SA, Shao F, Salthouse C, Mahmood U, Weissleder R. Upconverting luminescent nanomaterials: application to in vivo bioimaging. Chem Commun (Camb). 2009 Jul 28; (28):4188-90.
    View in: PubMed
  31. Sheth RA, Tam JM, Maricevich MA, Josephson L, Mahmood U. Quantitative endovascular fluorescence-based molecular imaging through blood of arterial wall inflammation. Radiology. 2009 Jun; 251(3):813-21.
    View in: PubMed
  32. Salthouse CD, Reynolds F, Tam JM, Josephson L, Mahmood U. Quantitative Measurement of Protease-Activity with Correction of Probe Delivery and Tissue Absorption Effects. Sens Actuators B Chem. 2009 May 6; 138(2):591-597.
    View in: PubMed
  33. Hung KE, Faca V, Song K, Sarracino DA, Richard LG, Krastins B, Forrester S, Porter A, Kunin A, Mahmood U, Haab BB, Hanash SM, Kucherlapati R. Comprehensive proteome analysis of an Apc mouse model uncovers proteins associated with intestinal tumorigenesis. Cancer Prev Res (Phila). 2009 Mar; 2(3):224-33.
    View in: PubMed
  34. Sheth RA, Upadhyay R, Stangenberg L, Sheth R, Weissleder R, Mahmood U. Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model. Gynecol Oncol. 2009 Mar; 112(3):616-22.
    View in: PubMed
  35. Salthouse C, Hildebrand S, Weissleder R, Mahmood U. Design and demonstration of a small-animal up-conversion imager. Opt Express. 2008 Dec 22; 16(26):21731-7.
    View in: PubMed
  36. Engelman JA, Chen L, Tan X, Crosby K, Guimaraes AR, Upadhyay R, Maira M, McNamara K, Perera SA, Song Y, Chirieac LR, Kaur R, Lightbown A, Simendinger J, Li T, Padera RF, García-Echeverría C, Weissleder R, Mahmood U, Cantley LC, Wong KK. Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. Nat Med. 2008 Dec; 14(12):1351-6.
    View in: PubMed
  37. Kalabis J, Oyama K, Okawa T, Nakagawa H, Michaylira CZ, Stairs DB, Figueiredo JL, Mahmood U, Diehl JA, Herlyn M, Rustgi AK. A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification. J Clin Invest. 2008 Dec; 118(12):3860-9.
    View in: PubMed
  38. Kozloff KM, Quinti L, Patntirapong S, Hauschka PV, Tung CH, Weissleder R, Mahmood U. Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo. Bone. 2009 Feb; 44(2):190-8.
    View in: PubMed
  39. Girnun GD, Chen L, Silvaggi J, Drapkin R, Chirieac LR, Padera RF, Upadhyay R, Vafai SB, Weissleder R, Mahmood U, Naseri E, Buckley S, Li D, Force J, McNamara K, Demetri G, Spiegelman BM, Wong KK. Regression of drug-resistant lung cancer by the combination of rosiglitazone and carboplatin. Clin Cancer Res. 2008 Oct 15; 14(20):6478-86.
    View in: PubMed
  40. Salthouse CD, Weissleder R, Mahmood U. Development of a time domain fluorimeter for fluorescent lifetime multiplexing analysis. IEEE Trans Biomed Circuits Syst. 2008 Sep 1; 2(3):204-11.
    View in: PubMed
  41. Gee MS, Upadhyay R, Bergquist H, Alencar H, Reynolds F, Maricevich M, Weissleder R, Josephson L, Mahmood U. Human breast cancer tumor models: molecular imaging of drug susceptibility and dosing during HER2/neu-targeted therapy. Radiology. 2008 Sep; 248(3):925-35.
    View in: PubMed
  42. Lin KY, Maricevich M, Bardeesy N, Weissleder R, Mahmood U. In vivo quantitative microvasculature phenotype imaging of healthy and malignant tissues using a fiber-optic confocal laser microprobe. Transl Oncol. 2008 Jul; 1(2):84-94.
    View in: PubMed
  43. Kelly KA, Bardeesy N, Anbazhagan R, Gurumurthy S, Berger J, Alencar H, Depinho RA, Mahmood U, Weissleder R. Targeted nanoparticles for imaging incipient pancreatic ductal adenocarcinoma. PLoS Med. 2008 Apr 15; 5(4):e85.
    View in: PubMed
  44. Gee MS, Upadhyay R, Bergquist H, Weissleder R, Josephson L, Mahmood U. Multiparameter noninvasive assessment of treatment susceptibility, drug target inhibition and tumor response guides cancer treatment. Int J Cancer. 2007 Dec 1; 121(11):2492-500.
    View in: PubMed
  45. Upadhyay R, Sheth RA, Weissleder R, Mahmood U. Quantitative real-time catheter-based fluorescence molecular imaging in mice. Radiology. 2007 Nov; 245(2):523-31.
    View in: PubMed
  46. Kozloff KM, Weissleder R, Mahmood U. Noninvasive optical detection of bone mineral. J Bone Miner Res. 2007 Aug; 22(8):1208-16.
    View in: PubMed
  47. Arwert E, Hingtgen S, Figueiredo JL, Bergquist H, Mahmood U, Weissleder R, Shah K. Visualizing the dynamics of EGFR activity and antiglioma therapies in vivo. Cancer Res. 2007 Aug 1; 67(15):7335-42.
    View in: PubMed
  48. Wu HJ, Sawaya H, Binstadt B, Brickelmaier M, Blasius A, Gorelik L, Mahmood U, Weissleder R, Carulli J, Benoist C, Mathis D. Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk. J Exp Med. 2007 Aug 6; 204(8):1911-22.
    View in: PubMed
  49. Tam JM, Upadhyay R, Pittet MJ, Weissleder R, Mahmood U. Improved in vivo whole-animal detection limits of green fluorescent protein-expressing tumor lines by spectral fluorescence imaging. Mol Imaging. 2007 Jul-Aug; 6(4):269-76.
    View in: PubMed
  50. Mahmood U, Upadhyay R. Current and Future Imaging Paradigms in Colorectal Cancer. Semin Colon Rectal Surg. 2007 Jun; 18(2):132-138.
    View in: PubMed
  51. Alencar H, Funovics MA, Figueiredo J, Sawaya H, Weissleder R, Mahmood U. Colonic adenocarcinomas: near-infrared microcatheter imaging of smart probes for early detection--study in mice. Radiology. 2007 Jul; 244(1):232-8.
    View in: PubMed
  52. Sheth RA, Upadhyay R, Weissleder R, Mahmood U. Real-time multichannel imaging framework for endoscopy, catheters, and fixed geometry intraoperative systems. Mol Imaging. 2007 May-Jun; 6(3):147-55.
    View in: PubMed
  53. Montet X, Figueiredo JL, Alencar H, Ntziachristos V, Mahmood U, Weissleder R. Tomographic fluorescence imaging of tumor vascular volume in mice. Radiology. 2007 Mar; 242(3):751-8.
    View in: PubMed
  54. Izmailova ES, Paz N, Alencar H, Chun M, Schopf L, Hepperle M, Lane JH, Harriman G, Xu Y, Ocain T, Weissleder R, Mahmood U, Healy AM, Jaffee B. Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis. Arthritis Rheum. 2007 Jan; 56(1):117-28.
    View in: PubMed
  55. Mahmood U, Wallace MB. Molecular imaging in gastrointestinal disease. Gastroenterology. 2007 Jan; 132(1):11-4.
    View in: PubMed
  56. Funovics MA, Alencar H, Montet X, Weissleder R, Mahmood U. Simultaneous fluorescence imaging of protease expression and vascularity during murine colonoscopy for colonic lesion characterization. Gastrointest Endosc. 2006 Oct; 64(4):589-97.
    View in: PubMed
  57. Kozloff KM, Quinti L, Tung C, Weissleder R, Mahmood U. Non-invasive imaging of osteoclast activity via near-infrared cathepsin-K activatable optical probe. J Musculoskelet Neuronal Interact. 2006 Oct-Dec; 6(4):353.
    View in: PubMed
  58. Newton JR, Kelly KA, Mahmood U, Weissleder R, Deutscher SL. In vivo selection of phage for the optical imaging of PC-3 human prostate carcinoma in mice. Neoplasia. 2006 Sep; 8(9):772-80.
    View in: PubMed
  59. Mahmood U. Can a clinically used chemoembolization vehicle improve transgene delivery? Radiology. 2006 Sep; 240(3):619-20.
    View in: PubMed
  60. Figueiredo JL, Alencar H, Weissleder R, Mahmood U. Near infrared thoracoscopy of tumoral protease activity for improved detection of peripheral lung cancer. Int J Cancer. 2006 Jun 1; 118(11):2672-7.
    View in: PubMed
  61. Deramaudt TB, Takaoka M, Upadhyay R, Bowser MJ, Porter J, Lee A, Rhoades B, Johnstone CN, Weissleder R, Hingorani SR, Mahmood U, Rustgi AK. N-cadherin and keratinocyte growth factor receptor mediate the functional interplay between Ki-RASG12V and p53V143A in promoting pancreatic cell migration, invasion, and tissue architecture disruption. Mol Cell Biol. 2006 Jun; 26(11):4185-200.
    View in: PubMed
  62. Ji H, Li D, Chen L, Shimamura T, Kobayashi S, McNamara K, Mahmood U, Mitchell A, Sun Y, Al-Hashem R, Chirieac LR, Padera R, Bronson RT, Kim W, Jänne PA, Shapiro GI, Tenen D, Johnson BE, Weissleder R, Sharpless NE, Wong KK. The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies. Cancer Cell. 2006 Jun; 9(6):485-95.
    View in: PubMed
  63. Bardeesy N, Aguirre AJ, Chu GC, Cheng KH, Lopez LV, Hezel AF, Feng B, Brennan C, Weissleder R, Mahmood U, Hanahan D, Redston MS, Chin L, Depinho RA. Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse. Proc Natl Acad Sci U S A. 2006 Apr 11; 103(15):5947-52.
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  64. Tréhin R, Figueiredo JL, Pittet MJ, Weissleder R, Josephson L, Mahmood U. Fluorescent nanoparticle uptake for brain tumor visualization. Neoplasia. 2006 Apr; 8(4):302-11.
    View in: PubMed
  65. Binstadt BA, Patel PR, Alencar H, Nigrovic PA, Lee DM, Mahmood U, Weissleder R, Mathis D, Benoist C. Particularities of the vasculature can promote the organ specificity of autoimmune attack. Nat Immunol. 2006 Mar; 7(3):284-92.
    View in: PubMed
  66. Zhang M, Alicot EM, Chiu I, Li J, Verna N, Vorup-Jensen T, Kessler B, Shimaoka M, Chan R, Friend D, Mahmood U, Weissleder R, Moore FD, Carroll MC. Identification of the target self-antigens in reperfusion injury. J Exp Med. 2006 Jan 23; 203(1):141-52.
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  67. Messerli SM, Prabhakar S, Tang Y, Mahmood U, Giovannini M, Weissleder R, Bronson R, Martuza R, Rabkin S, Breakefield XO. Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2. Hum Gene Ther. 2006 Jan; 17(1):20-30.
    View in: PubMed
  68. Brown AB, Mahmood U, Cortes ML, Tang Y, Dai G, Stemmer-Rachamimov A, Prabhakar S, Leishear K, Onda H, Kwiatkowski D, Weissleder R, Breakefield X. Magnetic resonance imaging and characterization of spontaneous lesions in a transgenic mouse model of tuberous sclerosis as a model for endothelial cell-based transgene delivery. Hum Gene Ther. 2005 Dec; 16(12):1367-76.
    View in: PubMed
  69. Alencar H, King R, Funovics M, Stout C, Weissleder R, Mahmood U. A novel mouse model for segmental orthotopic colon cancer. Int J Cancer. 2005 Nov 10; 117(3):335-9.
    View in: PubMed
  70. Alencar H, Mahmood U, Kawano Y, Hirata T, Weissleder R. Novel multiwavelength microscopic scanner for mouse imaging. Neoplasia. 2005 Nov; 7(11):977-83.
    View in: PubMed
  71. Kim YR, Yudina A, Figueiredo J, Reichardt W, Hu-Lowe D, Petrovsky A, Kang HW, Torres D, Mahmood U, Weissleder R, Bogdanov AA. Detection of early antiangiogenic effects in human colon adenocarcinoma xenografts: in vivo changes of tumor blood volume in response to experimental VEGFR tyrosine kinase inhibitor. Cancer Res. 2005 Oct 15; 65(20):9253-60.
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  72. Pivovarov M, Bhandary G, Mahmood U, Zahlmann G, Naraghi M, Weissleder R. MIPortal: a high capacity server for molecular imaging research. Mol Imaging. 2005 Oct-Dec; 4(4):425-31.
    View in: PubMed
  73. Turvey SE, Swart E, Denis MC, Mahmood U, Benoist C, Weissleder R, Mathis D. Noninvasive imaging of pancreatic inflammation and its reversal in type 1 diabetes. J Clin Invest. 2005 Sep; 115(9):2454-61.
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  74. Mahmood U, Josephson L. Molecular MR Imaging Probes. Proc IEEE Inst Electr Electron Eng. 2005 Apr; 93(4):800-808.
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  75. Chen WT, Mahmood U, Weissleder R, Tung CH. Arthritis imaging using a near-infrared fluorescence folate-targeted probe. Arthritis Res Ther. 2005; 7(2):R310-7.
    View in: PubMed
  76. Wunder A, Schellenberger E, Mahmood U, Bogdanov A, Müller-Ladner U, Weissleder R, Josephson L. Methotrexate-induced accumulation of fluorescent annexin V in collagen-induced arthritis. Mol Imaging. 2005 Jan-Mar; 4(1):1-6.
    View in: PubMed
  77. Mahmood U. Can MR imaging be used to track delivery of intravascularly administered stem cells? Radiology. 2004 Dec; 233(3):625-6.
    View in: PubMed
  78. Kelly K, Alencar H, Funovics M, Mahmood U, Weissleder R. Detection of invasive colon cancer using a novel, targeted, library-derived fluorescent peptide. Cancer Res. 2004 Sep 1; 64(17):6247-51.
    View in: PubMed
  79. Denis MC, Mahmood U, Benoist C, Mathis D, Weissleder R. Imaging inflammation of the pancreatic islets in type 1 diabetes. Proc Natl Acad Sci U S A. 2004 Aug 24; 101(34):12634-9.
    View in: PubMed
  80. Wunder A, Tung CH, Müller-Ladner U, Weissleder R, Mahmood U. In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response. Arthritis Rheum. 2004 Aug; 50(8):2459-65.
    View in: PubMed
  81. Mahmood U. Near infrared optical applications in molecular imaging. Earlier, more accurate assessment of disease presence, disease course, and efficacy of disease treatment. IEEE Eng Med Biol Mag. 2004 Jul-Aug; 23(4):58-66.
    View in: PubMed
  82. Funovics MA, Weissleder R, Mahmood U. Catheter-based in vivo imaging of enzyme activity and gene expression: feasibility study in mice. Radiology. 2004 Jun; 231(3):659-66.
    View in: PubMed
  83. Kircher MF, Mahmood U, King RS, Weissleder R, Josephson L. A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperative optical brain tumor delineation. Cancer Res. 2003 Dec 1; 63(23):8122-5.
    View in: PubMed
  84. Funovics MA, Alencar H, Su HS, Khazaie K, Weissleder R, Mahmood U. Miniaturized multichannel near infrared endoscope for mouse imaging. Mol Imaging. 2003 Oct; 2(4):350-7.
    View in: PubMed
  85. Mahmood U, Weissleder R. Near-infrared optical imaging of proteases in cancer. Mol Cancer Ther. 2003 May; 2(5):489-96.
    View in: PubMed
  86. Josephson L, Mahmood U, Wunderbaldinger P, Tang Y, Weissleder R. Pan and sentinel lymph node visualization using a near-infrared fluorescent probe. Mol Imaging. 2003 Jan; 2(1):18-23.
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  87. Schellingerhout D, Accorsi R, Mahmood U, Idoine J, Lanza RC, Weissleder R. Coded aperture nuclear scintigraphy: a novel small animal imaging technique. Mol Imaging. 2002 Oct; 1(4):344-53.
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  88. Mahmood U, Tung CH, Tang Y, Weissleder R. Feasibility of in vivo multichannel optical imaging of gene expression: experimental study in mice. Radiology. 2002 Aug; 224(2):446-51.
    View in: PubMed
  89. Chen J, Tung CH, Mahmood U, Ntziachristos V, Gyurko R, Fishman MC, Huang PL, Weissleder R. In vivo imaging of proteolytic activity in atherosclerosis. Circulation. 2002 Jun 11; 105(23):2766-71.
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  90. Mahmood U, Weissleder R. Some tools for molecular imaging. Acad Radiol. 2002 Jun; 9(6):629-31.
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  91. Josephson L, Kircher MF, Mahmood U, Tang Y, Weissleder R. Near-infrared fluorescent nanoparticles as combined MR/optical imaging probes. Bioconjug Chem. 2002 May-Jun; 13(3):554-60.
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  92. Ji H, Ohmura K, Mahmood U, Lee DM, Hofhuis FM, Boackle SA, Takahashi K, Holers VM, Walport M, Gerard C, Ezekowitz A, Carroll MC, Brenner M, Weissleder R, Verbeek JS, Duchatelle V, Degott C, Benoist C, Mathis D. Arthritis critically dependent on innate immune system players. Immunity. 2002 Feb; 16(2):157-68.
    View in: PubMed
  93. Bremer C, Bredow S, Mahmood U, Weissleder R, Tung CH. Optical imaging of matrix metalloproteinase-2 activity in tumors: feasibility study in a mouse model. Radiology. 2001 Nov; 221(2):523-9.
    View in: PubMed
  94. Weissleder R, Mahmood U. Molecular imaging. Radiology. 2001 May; 219(2):316-33.
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  95. Bremer C, Ntziachristos V, Mahmood U, Tung CH, Weissleder R. [Progress in optical imaging]. Radiologe. 2001 Feb; 41(2):131-7.
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  96. Tung CH, Mahmood U, Bredow S, Weissleder R. In vivo imaging of proteolytic enzyme activity using a novel molecular reporter. Cancer Res. 2000 Sep 1; 60(17):4953-8.
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  97. Weissleder R, Moore A, Mahmood U, Bhorade R, Benveniste H, Chiocca EA, Basilion JP. In vivo magnetic resonance imaging of transgene expression. Nat Med. 2000 Mar; 6(3):351-5.
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  98. Mahmood U, Tung CH, Bogdanov A, Weissleder R. Near-infrared optical imaging of protease activity for tumor detection. Radiology. 1999 Dec; 213(3):866-70.
    View in: PubMed
  99. Tung CH, Bredow S, Mahmood U, Weissleder R. Preparation of a cathepsin D sensitive near-infrared fluorescence probe for imaging. Bioconjug Chem. 1999 Sep-Oct; 10(5):892-6.
    View in: PubMed
  100. Weissleder R, Tung CH, Mahmood U, Bogdanov A. In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat Biotechnol. 1999 Apr; 17(4):375-8.
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  101. Street JC, Szwergold BS, Matei C, Kappler F, Mahmood U, Brown TR, Koutcher JA. Study of the metabolism of choline and phosphatidylcholine in tumors in vivo using phosphonium-choline. Magn Reson Med. 1997 Nov; 38(5):769-75.
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  102. Mahmood U, Street JC, Matei C, Ballon D, Martin DS, Koutcher JA. In vivo detection by 31P NMR of pentose phosphate pathway block secondary to biochemical modulation. NMR Biomed. 1996 May; 9(3):114-20.
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  103. Street JC, Mahmood U, Ballon D, Alfieri AA, Koutcher JA. 13C and 31P NMR investigation of effect of 6-aminonicotinamide on metabolism of RIF-1 tumor cells in vitro. J Biol Chem. 1996 Feb 23; 271(8):4113-9.
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  104. Mahmood U, Koutcher JA. Magnetic resonance spectroscopy and imaging in radiology. Med Phys. 1995 Nov; 22(11 Pt 2):1935-41.
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  105. Street JC, Mahmood U, Matei C, Koutcher JA. In vivo and in vitro studies of cyclophosphamide chemotherapy in a mouse mammary carcinoma by 31P NMR spectroscopy. NMR Biomed. 1995 Jun; 8(4):149-58.
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  106. Mahmood U, Alfieri AA, Ballon D, Traganos F, Koutcher JA. In vitro and in vivo 31P nuclear magnetic resonance measurements of metabolic changes post radiation. Cancer Res. 1995 Mar 15; 55(6):1248-54.
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  107. Mahmood U, Alfieri AA, Thaler H, Cowburn D, Koutcher JA. Radiation dose-dependent changes in tumor metabolism measured by 31P nuclear magnetic resonance spectroscopy. Cancer Res. 1994 Sep 15; 54(18):4885-91.
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  108. Balloon D, Mahmood U, Jakubowski A, Koutcher JA. Resolution enhanced NMR spectroscopy in biological systems via magnetic susceptibility matched sample immersion chambers. Magn Reson Med. 1993 Dec; 30(6):754-8.
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  109. Koutcher JA, Alfieri AA, Devitt ML, Rhee JG, Kornblith AB, Mahmood U, Merchant TE, Cowburn D. Quantitative changes in tumor metabolism, partial pressure of oxygen, and radiobiological oxygenation status postradiation. Cancer Res. 1992 Sep 1; 52(17):4620-7.
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  110. Mahmood U, Devitt ML, Kocheril PG, Sutanto-Ward E, Ballon D, Sigurdson ER, Koutcher JA. Quantitation of total metastatic tumor volume in the rat liver: correlation of MR and histologic measurements. J Magn Reson Imaging. 1992 May-Jun; 2(3):335-40.
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