Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution

Robert E. Strecker, PH.D.

TitleAssociate Professor of Psychiatry
InstitutionVeterans Affairs Boston Healthcare System
DepartmentPsychiatry
AddressBrockton V.A. Medical Center
Research 151 C
940 Belmont St
Brockton MA 02301
Phone774/826-1879
Fax774/826-1876

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. McCoy JG, Christie MA, Kim Y, Brennan R, Poeta DL, McCarley RW, Strecker RE. Chronic sleep restriction impairs spatial memory in rats. Neuroreport. 2013 Jan 23; 24(2):91-5.
    View in: PubMed
  2. Kelly JM, Strecker RE, Bianchi MT. Recent developments in home sleep-monitoring devices. ISRN Neurol. 2012; 2012:768794.
    View in: PubMed
  3. Brown RE, Basheer R, McKenna JT, Strecker RE, McCarley RW. Control of sleep and wakefulness. Physiol Rev. 2012 Jul; 92(3):1087-187.
    View in: PubMed
  4. Kim Y, Bolortuya Y, Chen L, Basheer R, McCarley RW, Strecker RE. Decoupling of sleepiness from sleep time and intensity during chronic sleep restriction: evidence for a role of the adenosine system. Sleep. 2012 Jun; 35(6):861-9.
    View in: PubMed
  5. McKenna JT, Christie MA, Jeffrey BA, McCoy JG, Lee E, Connolly NP, Ward CP, Strecker RE. Chronic ramelteon treatment in a mouse model of Alzheimer's disease. Arch Ital Biol. 2012 Mar; 150(1):5-14.
    View in: PubMed
  6. McCoy JG, Strecker RE. The cognitive cost of sleep lost. Neurobiol Learn Mem. 2011 Nov; 96(4):564-82.
    View in: PubMed
  7. Christie MA, McCarley RW, Strecker RE. Twenty-four hours, or five days, of continuous sleep deprivation or experimental sleep fragmentation do not alter thirst or motivation for water reward in rats. Behav Brain Res. 2010 Dec 25; 214(2):180-6.
    View in: PubMed
  8. McCoy JG, McKenna JT, Connolly NP, Poeta DL, Ling L, McCarley RW, Strecker RE. One week of exposure to intermittent hypoxia impairs attentional set-shifting in rats. Behav Brain Res. 2010 Jun 26; 210(1):123-6.
    View in: PubMed
  9. Tartar JL, McKenna JT, Ward CP, McCarley RW, Strecker RE, Brown RE. Sleep fragmentation reduces hippocampal CA1 pyramidal cell excitability and response to adenosine. Neurosci Lett. 2010 Jan 18; 469(1):1-5.
    View in: PubMed
  10. McKenna JT, Cordeira JW, Jeffrey BA, Ward CP, Winston S, McCarley RW, Strecker RE. c-Fos protein expression is increased in cholinergic neurons of the rodent basal forebrain during spontaneous and induced wakefulness. Brain Res Bull. 2009 Dec 16; 80(6):382-8.
    View in: PubMed
  11. Ward CP, McCoy JG, McKenna JT, Connolly NP, McCarley RW, Strecker RE. Spatial learning and memory deficits following exposure to 24 h of sleep fragmentation or intermittent hypoxia in a rat model of obstructive sleep apnea. Brain Res. 2009 Oct 19; 1294:128-37.
    View in: PubMed
  12. Ward CP, McCarley RW, Strecker RE. Experimental sleep fragmentation impairs spatial reference but not working memory in Fischer/Brown Norway rats. J Sleep Res. 2009 Jun; 18(2):238-44.
    View in: PubMed
  13. Christie MA, McKenna JT, Connolly NP, McCarley RW, Strecker RE. 24 hours of sleep deprivation in the rat increases sleepiness and decreases vigilance: introduction of the rat-psychomotor vigilance task. J Sleep Res. 2008 Dec; 17(4):376-84.
    View in: PubMed
  14. Christie MA, Bolortuya Y, Chen LC, McKenna JT, McCarley RW, Strecker RE. Microdialysis elevation of adenosine in the basal forebrain produces vigilance impairments in the rat psychomotor vigilance task. Sleep. 2008 Oct; 31(10):1393-8.
    View in: PubMed
  15. McKenna JT, Cordeira JW, Christie MA, Tartar JL, McCoy JG, Lee E, McCarley RW, Strecker RE. Assessing sleepiness in the rat: a multiple sleep latencies test compared to polysomnographic measures of sleepiness. J Sleep Res. 2008 Dec; 17(4):365-75.
    View in: PubMed
  16. McGuire M, Tartar JL, Cao Y, McCarley RW, White DP, Strecker RE, Ling L. Sleep fragmentation impairs ventilatory long-term facilitation via adenosine A1 receptors. J Physiol. 2008 Nov 1; 586(Pt 21):5215-29.
    View in: PubMed
  17. Tartar JL, Ward CP, Cordeira JW, Legare SL, Blanchette AJ, McCarley RW, Strecker RE. Experimental sleep fragmentation and sleep deprivation in rats increases exploration in an open field test of anxiety while increasing plasma corticosterone levels. Behav Brain Res. 2009 Feb 11; 197(2):450-3.
    View in: PubMed
  18. McKenna JT, Tartar JL, Ward CP, Thakkar MM, Cordeira JW, McCarley RW, Strecker RE. Sleep fragmentation elevates behavioral, electrographic and neurochemical measures of sleepiness. Neuroscience. 2007 Jun 8; 146(4):1462-73.
    View in: PubMed
  19. McCoy JG, Tartar JL, Bebis AC, Ward CP, McKenna JT, Baxter MG, McGaughy J, McCarley RW, Strecker RE. Experimental sleep fragmentation impairs attentional set-shifting in rats. Sleep. 2007 Jan; 30(1):52-60.
    View in: PubMed
  20. Tao R, Ma Z, McKenna JT, Thakkar MM, Winston S, Strecker RE, McCarley RW. Differential effect of orexins (hypocretins) on serotonin release in the dorsal and median raphe nuclei of freely behaving rats. Neuroscience. 2006 Sep 1; 141(3):1101-5.
    View in: PubMed
  21. Tartar JL, Ward CP, McKenna JT, Thakkar M, Arrigoni E, McCarley RW, Brown RE, Strecker RE. Hippocampal synaptic plasticity and spatial learning are impaired in a rat model of sleep fragmentation. Eur J Neurosci. 2006 May; 23(10):2739-48.
    View in: PubMed
  22. Strecker RE, Basheer R, McKenna JT, McCarley RW. Another chapter in the adenosine story. Sleep. 2006 Apr; 29(4):426-8.
    View in: PubMed
  23. Córdova CA, Said BO, McCarley RW, Baxter MG, Chiba AA, Strecker RE. Sleep deprivation in rats produces attentional impairments on a 5-choice serial reaction time task. Sleep. 2006 Jan; 29(1):69-76.
    View in: PubMed
  24. Ma Z, Strecker RE, McKenna JT, Thakkar MM, McCarley RW, Tao R. Effects on serotonin of (-)nicotine and dimethylphenylpiperazinium in the dorsal raphe and nucleus accumbens of freely behaving rats. Neuroscience. 2005; 135(3):949-58.
    View in: PubMed
  25. Lo CC, Chou T, Penzel T, Scammell TE, Strecker RE, Stanley HE, Ivanov PCh. Common scale-invariant patterns of sleep-wake transitions across mammalian species. Proc Natl Acad Sci U S A. 2004 Dec 14; 101(50):17545-8.
    View in: PubMed
  26. Basheer R, Strecker RE, Thakkar MM, McCarley RW. Adenosine and sleep-wake regulation. Prog Neurobiol. 2004 Aug; 73(6):379-96.
    View in: PubMed
  27. Ramesh V, Thakkar MM, Strecker RE, Basheer R, McCarley RW. Wakefulness-inducing effects of histamine in the basal forebrain of freely moving rats. Behav Brain Res. 2004 Jul 9; 152(2):271-8.
    View in: PubMed
  28. Thakkar MM, Delgiacco RA, Strecker RE, McCarley RW. Adenosinergic inhibition of basal forebrain wakefulness-active neurons: a simultaneous unit recording and microdialysis study in freely behaving cats. Neuroscience. 2003; 122(4):1107-13.
    View in: PubMed
  29. Kennedy RT, Watson CJ, Haskins WE, Powell DH, Strecker RE. In vivo neurochemical monitoring by microdialysis and capillary separations. Curr Opin Chem Biol. 2002 Oct; 6(5):659-65.
    View in: PubMed
  30. Thakkar MM, Strecker RE, McCarley RW. Phasic but not tonic REM-selective discharge of periaqueductal gray neurons in freely behaving animals: relevance to postulates of GABAergic inhibition of monoaminergic neurons. Brain Res. 2002 Aug 2; 945(2):276-80.
    View in: PubMed
  31. Strecker RE, Nalwalk J, Dauphin LJ, Thakkar MM, Chen Y, Ramesh V, Hough LB, McCarley RW. Extracellular histamine levels in the feline preoptic/anterior hypothalamic area during natural sleep-wakefulness and prolonged wakefulness: an in vivo microdialysis study. Neuroscience. 2002; 113(3):663-70.
    View in: PubMed
  32. Gaus SE, Strecker RE, Tate BA, Parker RA, Saper CB. Ventrolateral preoptic nucleus contains sleep-active, galaninergic neurons in multiple mammalian species. Neuroscience. 2002; 115(1):285-94.
    View in: PubMed
  33. Thakkar MM, Ramesh V, Strecker RE, McCarley RW. Microdialysis perfusion of orexin-A in the basal forebrain increases wakefulness in freely behaving rats. Arch Ital Biol. 2001 Apr; 139(3):313-28.
    View in: PubMed
  34. Basheer R, Porkka-Heiskanen T, Strecker RE, Thakkar MM, McCarley RW. Adenosine as a biological signal mediating sleepiness following prolonged wakefulness. Biol Signals Recept. 2000 Nov-Dec; 9(6):319-27.
    View in: PubMed
  35. Strecker RE, Morairty S, Thakkar MM, Porkka-Heiskanen T, Basheer R, Dauphin LJ, Rainnie DG, Portas CM, Greene RW, McCarley RW. Adenosinergic modulation of basal forebrain and preoptic/anterior hypothalamic neuronal activity in the control of behavioral state. Behav Brain Res. 2000 Nov; 115(2):183-204.
    View in: PubMed
  36. Porkka-Heiskanen T, Strecker RE, McCarley RW. Brain site-specificity of extracellular adenosine concentration changes during sleep deprivation and spontaneous sleep: an in vivo microdialysis study. Neuroscience. 2000; 99(3):507-17.
    View in: PubMed
  37. Liu X, Strecker RE, Brener J. A comparison of the effects of amphetamine and low doses of apomorphine on operant force production, inter-response times and response duration in rat. Psychopharmacology (Berl). 1999 Aug; 145(4):351-9.
    View in: PubMed
  38. Thakkar MM, Ramesh V, Cape EG, Winston S, Strecker RE, McCarley RW. REM sleep enhancement and behavioral cataplexy following orexin (hypocretin)-II receptor antisense perfusion in the pontine reticular formation. Sleep Res Online. 1999; 2(4):112-20.
    View in: PubMed
  39. Strecker RE, Thakkar MM, Porkka-Heiskanen T, Dauphin LJ, Bjørkum AA, McCarley RW. Behavioral state-related changes of extracellular serotonin concentration in the pedunculopontine tegmental nucleus: a microdialysis study in freely moving animals. Sleep Res Online. 1999; 2(2):21-7.
    View in: PubMed
  40. Thakkar MM, Strecker RE, McCarley RW. Behavioral state control through differential serotonergic inhibition in the mesopontine cholinergic nuclei: a simultaneous unit recording and microdialysis study. J Neurosci. 1998 Jul 15; 18(14):5490-7.
    View in: PubMed
  41. Liu X, Strecker RE, Brener J. Dopamine depletion in nucleus accumbens influences locomotion but not force and timing of operant responding. Pharmacol Biochem Behav. 1998 Mar; 59(3):737-45.
    View in: PubMed
  42. Porkka-Heiskanen T, Strecker RE, Thakkar M, Bjorkum AA, Greene RW, McCarley RW. Adenosine: a mediator of the sleep-inducing effects of prolonged wakefulness. Science. 1997 May 23; 276(5316):1265-8.
    View in: PubMed
  43. Kurata K, Ashby CR, Oberlender R, Tanii Y, Kurachi M, Rini NJ, Strecker RE. The characterization of the effect of locally applied N-methylquipazine, a 5-HT3 receptor agonist, on extracellular dopamine levels in the anterior medial prefrontal cortex in the rat: an in vivo microdialysis study. Synapse. 1996 Dec; 24(4):313-21.
    View in: PubMed
  44. Clark RN, Ashby CR, Dewey SL, Ramachandran PV, Strecker RE. Effect of acute and chronic fluoxetine on extracellular dopamine levels in the caudate-putamen and nucleus accumbens of rat. Synapse. 1996 Jul; 23(3):125-31.
    View in: PubMed
  45. Liu X, Strecker RE, Brener JM. Low doses of apomorphine suppress operant motor performance in rats. Pharmacol Biochem Behav. 1996 Feb; 53(2):335-40.
    View in: PubMed
  46. Strecker RE, Eberle WF, Ashby CR. Extracellular dopamine and its metabolites in the nucleus accumbens of Fischer and Lewis rats: basal levels and cocaine-induced changes. Life Sci. 1995; 56(6):PL135-41.
    View in: PubMed
  47. Strecker RE, Moneta ME. Electrical stimulation of the kindled hippocampus briefly increases extracellular dopamine in the nucleus accumbens. Neurosci Lett. 1994 Aug 1; 176(2):173-7.
    View in: PubMed
  48. McNeish CS, Svingos AL, Hitzemann R, Strecker RE. The 5-HT3 antagonist zacopride attenuates cocaine-induced increases in extracellular dopamine in rat nucleus accumbens. Pharmacol Biochem Behav. 1993 Aug; 45(4):759-63.
    View in: PubMed
  49. Basso MA, Strecker RE, Evinger C. Midbrain 6-hydroxydopamine lesions modulate blink reflex excitability. Exp Brain Res. 1993; 94(1):88-96.
    View in: PubMed
  50. Daszuta A, Kalén P, Strecker RE, Brundin P, Björklund A. Serotonin neurons grafted to the adult rat hippocampus. II. 5-HT release as studied by intracerebral microdialysis. Brain Res. 1989 Oct 2; 498(2):323-32.
    View in: PubMed
  51. Kalén P, Strecker RE, Rosengren E, Björklund A. Regulation of striatal serotonin release by the lateral habenula-dorsal raphe pathway in the rat as demonstrated by in vivo microdialysis: role of excitatory amino acids and GABA. Brain Res. 1989 Jul 17; 492(1-2):187-202.
    View in: PubMed
  52. Huffaker TK, Boss BD, Morgan AS, Neff NT, Strecker RE, Spence MS, Miao R. Xenografting of fetal pig ventral mesencephalon corrects motor asymmetry in the rat model of Parkinson's disease. Exp Brain Res. 1989; 77(2):329-36.
    View in: PubMed
  53. Daszuta A, Strecker RE, Brundin P, Björklund A. Serotonin neurons grafted to the adult rat hippocampus. I. Time course of growth as studied by immunohistochemistry and biochemistry. Brain Res. 1988 Aug 16; 458(1):1-19.
    View in: PubMed
  54. Nilsson OG, Brundin P, Widner H, Strecker RE, Björklund A. Human fetal basal forebrain neurons grafted to the denervated rat hippocampus produce an organotypic cholinergic reinnervation pattern. Brain Res. 1988 Jul 19; 456(1):193-8.
    View in: PubMed
  55. Nilsson OG, Strecker RE, Daszuta A, Björklund A. Combined cholinergic and serotonergic denervation of the forebrain produces severe deficits in a spatial learning task in the rat. Brain Res. 1988 Jun 21; 453(1-2):235-46.
    View in: PubMed
  56. Brundin P, Barbin G, Strecker RE, Isacson O, Prochiantz A, Björklund A. Survival and function of dissociated rat dopamine neurones grafted at different developmental stages or after being cultured in vitro. Brain Res. 1988 Apr 1; 467(2):233-43.
    View in: PubMed
  57. Gage FH, Brundin P, Strecker R, Dunnett SB, Isacson O, Bjorklund A. Intracerebral neuronal grafting in experimental animal models of age-related motor dysfunction. Ann N Y Acad Sci. 1988; 515:383-94.
    View in: PubMed
  58. Brundin P, Strecker RE, Widner H, Clarke DJ, Nilsson OG, Astedt B, Lindvall O, Björklund A. Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: immunological aspects, spontaneous and drug-induced behaviour, and dopamine release. Exp Brain Res. 1988; 70(1):192-208.
    View in: PubMed
  59. Strecker RE, Sharp T, Brundin P, Zetterström T, Ungerstedt U, Björklund A. Autoregulation of dopamine release and metabolism by intrastriatal nigral grafts as revealed by intracerebral dialysis. Neuroscience. 1987 Jul; 22(1):169-78.
    View in: PubMed
  60. Brundin P, Strecker RE, Lindvall O, Isacson O, Nilsson OG, Barbin G, Prochiantz A, Forni C, Nieoullon A, Widner H, et al. Intracerebral grafting of dopamine neurons. Experimental basis for clinical trials in patients with Parkinson's disease. Ann N Y Acad Sci. 1987; 495:473-96.
    View in: PubMed
  61. Brundin P, Strecker RE, Londos E, Björklund A. Dopamine neurons grafted unilaterally to the nucleus accumbens affect drug-induced circling and locomotion. Exp Brain Res. 1987; 69(1):183-94.
    View in: PubMed
  62. Rasmussen K, Strecker RE, Jacobs BL. Single unit response of noradrenergic, serotonergic and dopaminergic neurons in freely moving cats to simple sensory stimuli. Brain Res. 1986 Mar 26; 369(1-2):336-40.
    View in: PubMed
  63. Strecker RE, Jacobs BL. Substantia nigra dopaminergic unit activity in behaving cats: effect of arousal on spontaneous discharge and sensory evoked activity. Brain Res. 1985 Dec 30; 361(1-2):339-50.
    View in: PubMed
  64. Strecker RE, Steinfels GF, Abercrombie ED, Jacobs BL. Caudate unit activity in freely moving cats: effects of phasic auditory and visual stimuli. Brain Res. 1985 Mar 11; 329(1-2):350-3.
    View in: PubMed
  65. Steinfels GF, Heym J, Strecker RE, Jacobs BL. Raphe unit activity in freely moving cats is altered by manipulations of central but not peripheral motor systems. Brain Res. 1983 Nov 21; 279(1-2):77-84.
    View in: PubMed
  66. Steinfels GF, Heym J, Strecker RE, Jacobs BL. Response of dopaminergic neurons in cat to auditory stimuli presented across the sleep-waking cycle. Brain Res. 1983 Oct 24; 277(1):150-4.
    View in: PubMed
  67. Strecker RE, Steinfels GF, Jacobs BL. Dopaminergic unit activity in freely moving cats: lack of relationship to feeding, satiety, and glucose injections. Brain Res. 1983 Feb 7; 260(2):317-21.
    View in: PubMed
  68. Steinfels GF, Heym J, Strecker RE, Jacobs BL. Behavioral correlates of dopaminergic unit activity in freely moving cats. Brain Res. 1983 Jan 10; 258(2):217-28.
    View in: PubMed
  69. Strecker RE, Roberts DC, Koob GF. Apomorphine-induced facilitation of intracranial self-stimulation following dopamine denervation of the nucleus accumbens. Pharmacol Biochem Behav. 1982 Nov; 17(5):1015-8.
    View in: PubMed
  70. Joyce EM, Koob GF, Strecker R, Iversen SD, Bloom FE. The behavioural effects of enkephalin analogues injected into the ventral tegmental area and globus pallidus. Brain Res. 1981 Sep 28; 221(2):359-70.
    View in: PubMed
  71. Koob GF, Strecker RE, Bloom FE. Effects of naloxone on the anticonflict properties of alcohol and chlordiazepoxide. Subst Alcohol Actions Misuse. 1980; 1(5-6):447-57.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact Human Resources at faculty_serviceshms.harvard.edu.
Strecker's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
See all (306) concept(s)
_
Co-Authors
See all (15) people
_
Similar People
See all (60) people
_
Same Department
Search Department
Physical Neighbors
_