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Last Name
Institution

Yves Boucher, PH.D.

TitleAssociate Professor of Radiation Oncology
InstitutionMassachusetts General Hospital
DepartmentRadiation Oncology
AddressMassachusetts General Hospital
Radiation Oncology, Cox 7
55 Fruit St
Boston MA 02114
Phone617/726-8143
Fax617/726-1962

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Liu J, Liao S, Diop-Frimpong B, Chen W, Goel S, Naxerova K, Ancukiewicz M, Boucher Y, Jain RK, Xu L. TGF-ß blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma. Proc Natl Acad Sci U S A. 2012 Oct 9; 109(41):16618-23.
    View in: PubMed
  2. Stylianopoulos T, Martin JD, Chauhan VP, Jain SR, Diop-Frimpong B, Bardeesy N, Smith BL, Ferrone CR, Hornicek FJ, Boucher Y, Munn LL, Jain RK. Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors. Proc Natl Acad Sci U S A. 2012 Sep 18; 109(38):15101-8.
    View in: PubMed
  3. Zerari-Mailly F, Braud A, Davido N, Touré B, Azérad J, Boucher Y. Glutamate control of pulpal blood flow in the incisor dental pulp of the rat. Eur J Oral Sci. 2012 Oct; 120(5):402-7.
    View in: PubMed
  4. Raut CP, Boucher Y, Duda DG, Morgan JA, Quek R, Ancukiewicz M, Lahdenranta J, Eder JP, Demetri GD, Jain RK. Effects of sorafenib on intra-tumoral interstitial fluid pressure and circulating biomarkers in patients with refractory sarcomas (NCI protocol 6948). PLoS One. 2012; 7(2):e26331.
    View in: PubMed
  5. Tse JM, Cheng G, Tyrrell JA, Wilcox-Adelman SA, Boucher Y, Jain RK, Munn LL. Mechanical compression drives cancer cells toward invasive phenotype. Proc Natl Acad Sci U S A. 2012 Jan 17; 109(3):911-6.
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  6. Braud A, Vandenbeuch A, Zerari-Mailly F, Boucher Y. Dental afferents project onto gustatory neurons in the nucleus of the solitary tract. J Dent Res. 2012 Feb; 91(2):215-20.
    View in: PubMed
  7. Touré B, Faye B, Kane AW, Lo CM, Niang B, Boucher Y. Analysis of reasons for extraction of endodontically treated teeth: a prospective study. J Endod. 2011 Nov; 37(11):1512-5.
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  8. Goel S, Duda DG, Xu L, Munn LL, Boucher Y, Fukumura D, Jain RK. Normalization of the vasculature for treatment of cancer and other diseases. Physiol Rev. 2011 Jul; 91(3):1071-121.
    View in: PubMed
  9. Perentes JY, Kirkpatrick ND, Nagano S, Smith EY, Shaver CM, Sgroi D, Garkavtsev I, Munn LL, Jain RK, Boucher Y. Cancer cell-associated MT1-MMP promotes blood vessel invasion and distant metastasis in triple-negative mammary tumors. Cancer Res. 2011 Jul 1; 71(13):4527-38.
    View in: PubMed
  10. Davido N, Rigolet A, Kerner S, Gruffaz F, Boucher Y. Case of Ewing's sarcoma misdiagnosed as a periapical lesion of maxillary incisor. J Endod. 2011 Feb; 37(2):259-64.
    View in: PubMed
  11. Diop-Frimpong B, Chauhan VP, Krane S, Boucher Y, Jain RK. Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors. Proc Natl Acad Sci U S A. 2011 Feb 15; 108(7):2909-14.
    View in: PubMed
  12. Chauhan VP, Stylianopoulos T, Boucher Y, Jain RK. Delivery of molecular and nanoscale medicine to tumors: transport barriers and strategies. Annu Rev Chem Biomol Eng. 2011; 2:281-98.
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  13. Braud A, Boucher Y, Zerari-Mailly F. Vesicular glutamate transporters localization in the rat lingual papillae. Neuroreport. 2010 Jan 6; 21(1):64-7.
    View in: PubMed
  14. Felizardo R, Boucher Y, Braud A, Carstens E, Dauvergne C, Zerari-Mailly F. Trigeminal projections on gustatory neurons of the nucleus of the solitary tract: a double-label strategy using electrical stimulation of the chorda tympani and tracer injection in the lingual nerve. Brain Res. 2009 Sep 8; 1288:60-8.
    View in: PubMed
  15. Chauhan VP, Lanning RM, Diop-Frimpong B, Mok W, Brown EB, Padera TP, Boucher Y, Jain RK. Multiscale measurements distinguish cellular and interstitial hindrances to diffusion in vivo. Biophys J. 2009 Jul 8; 97(1):330-6.
    View in: PubMed
  16. Raliou M, Wiencis A, Pillias AM, Planchais A, Eloit C, Boucher Y, Trotier D, Montmayeur JP, Faurion A. Nonsynonymous single nucleotide polymorphisms in human tas1r1, tas1r3, and mGluR1 and individual taste sensitivity to glutamate. Am J Clin Nutr. 2009 Sep; 90(3):789S-799S.
    View in: PubMed
  17. Willett CG, Duda DG, di Tomaso E, Boucher Y, Ancukiewicz M, Sahani DV, Lahdenranta J, Chung DC, Fischman AJ, Lauwers GY, Shellito P, Czito BG, Wong TZ, Paulson E, Poleski M, Vujaskovic Z, Bentley R, Chen HX, Clark JW, Jain RK. Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study. J Clin Oncol. 2009 Jun 20; 27(18):3020-6.
    View in: PubMed
  18. Mok W, Stylianopoulos T, Boucher Y, Jain RK. Mathematical modeling of herpes simplex virus distribution in solid tumors: implications for cancer gene therapy. Clin Cancer Res. 2009 Apr 1; 15(7):2352-60.
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  19. Perentes JY, McKee TD, Ley CD, Mathiew H, Dawson M, Padera TP, Munn LL, Jain RK, Boucher Y. In vivo imaging of extracellular matrix remodeling by tumor-associated fibroblasts. Nat Methods. 2009 Feb; 6(2):143-5.
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  20. Raliou M, Boucher Y, Wiencis A, Bézirard V, Pernollet JC, Trotier D, Faurion A, Montmayeur JP. Tas1R1-Tas1R3 taste receptor variants in human fungiform papillae. Neurosci Lett. 2009 Feb 27; 451(3):217-21.
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  21. Touré B, Kane AW, Mbodji EB, Ndiaye C, Bane K, Gaye F, Boucher Y. [Prevalence of fixed prosthesis-related periodontitis in Senegal]. Odontostomatol Trop. 2008 Sep; 31(123):11-6.
    View in: PubMed
  22. Nagano S, Perentes JY, Jain RK, Boucher Y. Cancer cell death enhances the penetration and efficacy of oncolytic herpes simplex virus in tumors. Cancer Res. 2008 May 15; 68(10):3795-802.
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  23. Mbaye M, Touré B, Kane AW, Leye F, Bane K, Boucher Y. [Radiographic study of the canal anatomy of mandibular premolars in a Senegalese population]. Dakar Med. 2008; 53(3):267-71.
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  24. Mok W, Boucher Y, Jain RK. Matrix metalloproteinases-1 and -8 improve the distribution and efficacy of an oncolytic virus. Cancer Res. 2007 Nov 15; 67(22):10664-8.
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  25. Touré B, Kane AW, Sarr M, Ngom CT, Boucher Y. Prevalence and technical quality of root fillings in Dakar, Senegal. Int Endod J. 2008 Jan; 41(1):41-9.
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  26. Kozin SV, Winkler F, Garkavtsev I, Hicklin DJ, Jain RK, Boucher Y. Human tumor xenografts recurring after radiotherapy are more sensitive to anti-vascular endothelial growth factor receptor-2 treatment than treatment-naive tumors. Cancer Res. 2007 Jun 1; 67(11):5076-82.
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  27. Ogawa K, Boucher Y, Kashiwagi S, Fukumura D, Chen D, Gerweck LE. Influence of tumor cell and stroma sensitivity on tumor response to radiation. Cancer Res. 2007 May 1; 67(9):4016-21.
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  28. Willett CG, Duda DG, di Tomaso E, Boucher Y, Czito BG, Vujaskovic Z, Vlahovic G, Bendell J, Cohen KS, Hurwitz HI, Bentley R, Lauwers GY, Poleski M, Wong TZ, Paulson E, Ludwig KA, Jain RK. Complete pathological response to bevacizumab and chemoradiation in advanced rectal cancer. Nat Clin Pract Oncol. 2007 May; 4(5):316-21.
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  29. Lawenda BD, Smith DE, Xu L, Niemierko A, Silverstein JR, Boucher Y, Kashiwagi S, Held KD, Jain RK, Loeffler JS, Eisenberg DM, Blumberg JB. Do the dietary supplements epigallocatechin gallate or vitamin e cause a radiomodifying response on tumors in vivo? A pilot study with murine breast carcinoma. J Soc Integr Oncol. 2007; 5(1):11-7.
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  30. Touré B, Kane AW, Diouf A, Faye B, Boucher Y. Preoperative pain and medications used in emergency patients with irreversible acute pulpitis or acute apical periodontitis: a prospective comparative study. J Orofac Pain. 2007; 21(4):303-8.
    View in: PubMed
  31. Boucher Y, Berteretche MV, Farhang F, Arvy MP, Azérad J, Faurion A. Taste deficits related to dental deafferentation: an electrogustometric study in humans. Eur J Oral Sci. 2006 Dec; 114(6):456-64.
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  32. Willett CG, Kozin SV, Duda DG, di Tomaso E, Kozak KR, Boucher Y, Jain RK. Combined vascular endothelial growth factor-targeted therapy and radiotherapy for rectal cancer: theory and clinical practice. Semin Oncol. 2006 Oct; 33(5 Suppl 10):S35-40.
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  33. Simons CT, Boucher Y, Carstens MI, Carstens E. Nicotine suppression of gustatory responses of neurons in the nucleus of the solitary tract. J Neurophysiol. 2006 Oct; 96(4):1877-86.
    View in: PubMed
  34. McKee TD, Grandi P, Mok W, Alexandrakis G, Insin N, Zimmer JP, Bawendi MG, Boucher Y, Breakefield XO, Jain RK. Degradation of fibrillar collagen in a human melanoma xenograft improves the efficacy of an oncolytic herpes simplex virus vector. Cancer Res. 2006 Mar 1; 66(5):2509-13.
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  35. Willett CG, Boucher Y, Duda DG, di Tomaso E, Munn LL, Tong RT, Kozin SV, Petit L, Jain RK, Chung DC, Sahani DV, Kalva SP, Cohen KS, Scadden DT, Fischman AJ, Clark JW, Ryan DP, Zhu AX, Blaszkowsky LS, Shellito PC, Mino-Kenudson M, Lauwers GY. Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients. J Clin Oncol. 2005 Nov 1; 23(31):8136-9.
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  36. Demou ZN, Awad M, McKee T, Perentes JY, Wang X, Munn LL, Jain RK, Boucher Y. Lack of telopeptides in fibrillar collagen I promotes the invasion of a metastatic breast tumor cell line. Cancer Res. 2005 Jul 1; 65(13):5674-82.
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  37. Taghian AG, Abi-Raad R, Assaad SI, Casty A, Ancukiewicz M, Yeh E, Molokhia P, Attia K, Sullivan T, Kuter I, Boucher Y, Powell SN. Paclitaxel decreases the interstitial fluid pressure and improves oxygenation in breast cancers in patients treated with neoadjuvant chemotherapy: clinical implications. J Clin Oncol. 2005 Mar 20; 23(9):1951-61.
    View in: PubMed
  38. Garkavtsev I, Boucher Y. An intact ING1-P53 pathway can potentiate the cytotoxic effects of taxol. Cancer Biol Ther. 2005 Jan; 4(1):48-9.
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  39. Tong RT, Boucher Y, Kozin SV, Winkler F, Hicklin DJ, Jain RK. Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors. Cancer Res. 2004 Jun 1; 64(11):3731-6.
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  40. Brown EB, Boucher Y, Nasser S, Jain RK. Measurement of macromolecular diffusion coefficients in human tumors. Microvasc Res. 2004 May; 67(3):231-6.
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  41. Willett CG, Boucher Y, di Tomaso E, Duda DG, Munn LL, Tong RT, Chung DC, Sahani DV, Kalva SP, Kozin SV, Mino M, Cohen KS, Scadden DT, Hartford AC, Fischman AJ, Clark JW, Ryan DP, Zhu AX, Blaszkowsky LS, Chen HX, Shellito PC, Lauwers GY, Jain RK. Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer. Nat Med. 2004 Feb; 10(2):145-7.
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  42. Alexandrakis G, Brown EB, Tong RT, McKee TD, Campbell RB, Boucher Y, Jain RK. Two-photon fluorescence correlation microscopy reveals the two-phase nature of transport in tumors. Nat Med. 2004 Feb; 10(2):203-7.
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  43. Padera TP, Boucher Y, Jain RK. Correspondence re: S. Maula et al., intratumoral lymphatics are essential for the metastatic spread and prognosis in squamous cell carcinoma of the head and neck. Cancer Res., 63: 1920-1926, 2003. Cancer Res. 2003 Dec 1; 63(23):8555-6; author reply 8558.
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  44. Znati CA, Rosenstein M, McKee TD, Brown E, Turner D, Bloomer WD, Watkins S, Jain RK, Boucher Y. Irradiation reduces interstitial fluid transport and increases the collagen content in tumors. Clin Cancer Res. 2003 Nov 15; 9(15):5508-13.
    View in: PubMed
  45. Roose T, Netti PA, Munn LL, Boucher Y, Jain RK. Solid stress generated by spheroid growth estimated using a linear poroelasticity model small star, filled. Microvasc Res. 2003 Nov; 66(3):204-12.
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  46. Boucher Y, Simons CT, Faurion A, Azérad J, Carstens E. Trigeminal modulation of gustatory neurons in the nucleus of the solitary tract. Brain Res. 2003 May 30; 973(2):265-74.
    View in: PubMed
  47. Brown E, McKee T, diTomaso E, Pluen A, Seed B, Boucher Y, Jain RK. Dynamic imaging of collagen and its modulation in tumors in vivo using second-harmonic generation. Nat Med. 2003 Jun; 9(6):796-800.
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  48. Simons CT, Boucher Y, Carstens MI, Carstens E. Lack of quinine-evoked activity in rat trigeminal subnucleus caudalis. Chem Senses. 2003 Mar; 28(3):253-9.
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  49. Simons CT, Boucher Y, Carstens E. Suppression of central taste transmission by oral capsaicin. J Neurosci. 2003 Feb 1; 23(3):978-85.
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  50. Boucher Y, Simons CT, Cuellar JM, Jung SW, Carstens MI, Carstens E. Activation of brain stem neurons by irritant chemical stimulation of the throat assessed by c-fos immunohistochemistry. Exp Brain Res. 2003 Jan; 148(2):211-8.
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  51. Ramanujan S, Pluen A, McKee TD, Brown EB, Boucher Y, Jain RK. Diffusion and convection in collagen gels: implications for transport in the tumor interstitium. Biophys J. 2002 Sep; 83(3):1650-60.
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  52. Padera TP, Kadambi A, di Tomaso E, Carreira CM, Brown EB, Boucher Y, Choi NC, Mathisen D, Wain J, Mark EJ, Munn LL, Jain RK. Lymphatic metastasis in the absence of functional intratumor lymphatics. Science. 2002 Jun 7; 296(5574):1883-6.
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  53. Hofman S, Azérad J, Boucher Y. Effects of excitatory amino acid receptor antagonists on pulpal blood flow of the rat mandibular incisor. J Dent Res. 2002 Apr; 81(4):253-8.
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  54. Koike C, McKee TD, Pluen A, Ramanujan S, Burton K, Munn LL, Boucher Y, Jain RK. Solid stress facilitates spheroid formation: potential involvement of hyaluronan. Br J Cancer. 2002 Mar 18; 86(6):947-53.
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  55. Boucher Y, Matossian L, Rilliard F, Machtou P. Radiographic evaluation of the prevalence and technical quality of root canal treatment in a French subpopulation. Int Endod J. 2002 Mar; 35(3):229-38.
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  56. Mouta Carreira C, Nasser SM, di Tomaso E, Padera TP, Boucher Y, Tomarev SI, Jain RK. LYVE-1 is not restricted to the lymph vessels: expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis. Cancer Res. 2001 Nov 15; 61(22):8079-84.
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  57. Davies Cde L, Melder RJ, Munn LL, Mouta-Carreira C, Jain RK, Boucher Y. Decorin inhibits endothelial migration and tube-like structure formation: role of thrombospondin-1. Microvasc Res. 2001 Jul; 62(1):26-42.
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  58. Pluen A, Boucher Y, Ramanujan S, McKee TD, Gohongi T, di Tomaso E, Brown EB, Izumi Y, Campbell RB, Berk DA, Jain RK. Role of tumor-host interactions in interstitial diffusion of macromolecules: cranial vs. subcutaneous tumors. Proc Natl Acad Sci U S A. 2001 Apr 10; 98(8):4628-33.
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  59. Boucher Y, Hofman S, Joulin Y, Azérad J. Effects of BP 2-94, a selective H(3)-receptor agonist, on blood flow and vascular permeability of the rat mandibular incisor pulp. Arch Oral Biol. 2001 Jan; 46(1):83-92.
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  60. Kozin SV, Boucher Y, Hicklin DJ, Bohlen P, Jain RK, Suit HD. Vascular endothelial growth factor receptor-2-blocking antibody potentiates radiation-induced long-term control of human tumor xenografts. Cancer Res. 2001 Jan 1; 61(1):39-44.
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  61. Lee CG, Heijn M, di Tomaso E, Griffon-Etienne G, Ancukiewicz M, Koike C, Park KR, Ferrara N, Jain RK, Suit HD, Boucher Y. Anti-Vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions. Cancer Res. 2000 Oct 1; 60(19):5565-70.
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  62. Stohrer M, Boucher Y, Stangassinger M, Jain RK. Oncotic pressure in solid tumors is elevated. Cancer Res. 2000 Aug 1; 60(15):4251-5.
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  63. Briand L, Huet J, Perez V, Lenoir G, Nespoulous C, Boucher Y, Trotier D, Pernollet JC. Odorant and pheromone binding by aphrodisin, a hamster aphrodisiac protein. FEBS Lett. 2000 Jul 7; 476(3):179-85.
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  64. Sauveur G, Sobel M, Boucher Y. Utilization of gutta-percha for retrograde root fillings. Endod Dent Traumatol. 2000 Jun; 16(3):128-31.
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  65. Boucher Y, Sobel M, Sauveur G. Persistent pain related to root canal filling and apical fenestration: a case report. J Endod. 2000 Apr; 26(4):242-4.
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  66. Swartz MA, Kaipainen A, Netti PA, Brekken C, Boucher Y, Grodzinsky AJ, Jain RK. Mechanics of interstitial-lymphatic fluid transport: theoretical foundation and experimental validation. J Biomech. 1999 Dec; 32(12):1297-307.
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  67. Gohongi T, Fukumura D, Boucher Y, Yun CO, Soff GA, Compton C, Todoroki T, Jain RK. Tumor-host interactions in the gallbladder suppress distal angiogenesis and tumor growth: involvement of transforming growth factor beta1. Nat Med. 1999 Oct; 5(10):1203-8.
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  68. Griffon-Etienne G, Boucher Y, Brekken C, Suit HD, Jain RK. Taxane-induced apoptosis decompresses blood vessels and lowers interstitial fluid pressure in solid tumors: clinical implications. Cancer Res. 1999 Aug 1; 59(15):3776-82.
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  69. Sauveur G, Roth F, Sobel M, Boucher Y. The control of haemorrhage at the operative site during periradicular surgery. Int Endod J. 1999 May; 32(3):225-8.
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  70. Netti PA, Hamberg LM, Babich JW, Kierstead D, Graham W, Hunter GJ, Wolf GL, Fischman A, Boucher Y, Jain RK. Enhancement of fluid filtration across tumor vessels: implication for delivery of macromolecules. Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6):3137-42.
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  71. Boucher Y, Brekken C, Netti PA, Baxter LT, Jain RK. Intratumoral infusion of fluid: estimation of hydraulic conductivity and implications for the delivery of therapeutic agents. Br J Cancer. 1998 Dec; 78(11):1442-8.
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  72. Sauveur G, Boccara E, Colon P, Sobel M, Boucher Y. A photoelastimetric analysis of stress induced by root-end resection. J Endod. 1998 Nov; 24(11):740-3.
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  73. Sauveur G, Boucher Y. A teaching model for endodontic surgery. Int Endod J. 1998 Mar; 31(2):133-6.
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  74. Griffon-Etienne G, Boucher Y, Jain RK, Suit HD. Effects of needle insertion in tumors on interstitial fluid pressure. Microvasc Res. 1997 Sep; 54(2):174-7.
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  75. Sauveur G, Sobel M, Boucher Y. Surgical treatment of a lateroradicular lesion on an invaginated lateral incisor (dens in dente). Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997 Jun; 83(6):703-6.
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  76. Sauveur G, Roth F, Sobel M, Boucher Y. Surgical treatment of a periradicular lesion on an invaginated maxillary lateral incisor (dens in dente). Int Endod J. 1997 Mar; 30(2):145-9.
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  77. Boucher Y, Salehi H, Witwer B, Harsh GR, Jain RK. Interstitial fluid pressure in intracranial tumours in patients and in rodents. Br J Cancer. 1997; 75(6):829-36.
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  78. Boucher Y, Leunig M, Jain RK. Tumor angiogenesis and interstitial hypertension. Cancer Res. 1996 Sep 15; 56(18):4264-6.
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  79. Kristensen CA, Nozue M, Boucher Y, Jain RK. Reduction of interstitial fluid pressure after TNF-alpha treatment of three human melanoma xenografts. Br J Cancer. 1996 Aug; 74(4):533-6.
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  80. Netti PA, Roberge S, Boucher Y, Baxter LT, Jain RK. Effect of transvascular fluid exchange on pressure-flow relationship in tumors: a proposed mechanism for tumor blood flow heterogeneity. Microvasc Res. 1996 Jul; 52(1):27-46.
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  81. Hartmann A, Azérad J, Boucher Y. Environmental effects on laser Doppler pulpal blood-flow measurements in man. Arch Oral Biol. 1996 Apr; 41(4):333-9.
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  82. Znati CA, Rosenstein M, Boucher Y, Epperly MW, Bloomer WD, Jain RK. Effect of radiation on interstitial fluid pressure and oxygenation in a human tumor xenograft. Cancer Res. 1996 Mar 1; 56(5):964-68.
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  83. Netti PA, Baxter LT, Boucher Y, Skalak R, Jain RK. Time-dependent behavior of interstitial fluid pressure in solid tumors: implications for drug delivery. Cancer Res. 1995 Nov 15; 55(22):5451-8.
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  84. Zlotecki RA, Baxter LT, Boucher Y, Jain RK. Pharmacologic modification of tumor blood flow and interstitial fluid pressure in a human tumor xenograft: network analysis and mechanistic interpretation. Microvasc Res. 1995 Nov; 50(3):429-43.
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  85. Boucher Y, Lee I, Jain RK. Lack of general correlation between interstitial fluid pressure and oxygen partial pressure in solid tumors. Microvasc Res. 1995 Sep; 50(2):175-82.
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  86. Yuan F, Salehi HA, Boucher Y, Vasthare US, Tuma RF, Jain RK. Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows. Cancer Res. 1994 Sep 1; 54(17):4564-8.
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  87. Lee I, Demhartner TJ, Boucher Y, Jain RK, Intaglietta M. Effect of hemodilution and resuscitation on tumor interstitial fluid pressure, blood flow, and oxygenation. Microvasc Res. 1994 Jul; 48(1):1-12.
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  88. Lee I, Boucher Y, Demhartner TJ, Jain RK. Changes in tumour blood flow, oxygenation and interstitial fluid pressure induced by pentoxifylline. Br J Cancer. 1994 Mar; 69(3):492-6.
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  89. Kristjansen PE, Boucher Y, Jain RK. Dexamethasone reduces the interstitial fluid pressure in a human colon adenocarcinoma xenograft. Cancer Res. 1993 Oct 15; 53(20):4764-6.
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  90. Boucher Y, Pollin B, Azérad J. Microinfusions of excitatory amino acid antagonists into the trigeminal sensory complex antagonize the jaw opening reflex in freely moving rats. Brain Res. 1993 Jun 18; 614(1-2):155-63.
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  91. Zlotecki RA, Boucher Y, Lee I, Baxter LT, Jain RK. Effect of angiotensin II induced hypertension on tumor blood flow and interstitial fluid pressure. Cancer Res. 1993 Jun 1; 53(11):2466-8.
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  92. Leunig M, Yuan F, Menger MD, Boucher Y, Goetz AE, Messmer K, Jain RK. Angiogenesis, microvascular architecture, microhemodynamics, and interstitial fluid pressure during early growth of human adenocarcinoma LS174T in SCID mice. Cancer Res. 1992 Dec 1; 52(23):6553-60.
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  93. Less JR, Posner MC, Boucher Y, Borochovitz D, Wolmark N, Jain RK. Interstitial hypertension in human breast and colorectal tumors. Cancer Res. 1992 Nov 15; 52(22):6371-4.
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  94. Boucher Y, Jain RK. Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: implications for vascular collapse. Cancer Res. 1992 Sep 15; 52(18):5110-4.
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  95. Lee I, Boucher Y, Jain RK. Nicotinamide can lower tumor interstitial fluid pressure: mechanistic and therapeutic implications. Cancer Res. 1992 Jun 1; 52(11):3237-40.
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  96. Azérad J, Boucher Y, Pollin B. [Demonstration of glutamate in primary sensory trigeminal neurons innervating dental pulp in rats]. C R Acad Sci III. 1992; 314(10):469-75.
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  97. Roh HD, Boucher Y, Kalnicki S, Buchsbaum R, Bloomer WD, Jain RK. Interstitial hypertension in carcinoma of uterine cervix in patients: possible correlation with tumor oxygenation and radiation response. Cancer Res. 1991 Dec 15; 51(24):6695-8.
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  98. Boucher Y, Kirkwood JM, Opacic D, Desantis M, Jain RK. Interstitial hypertension in superficial metastatic melanomas in humans. Cancer Res. 1991 Dec 15; 51(24):6691-4.
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  99. Boucher Y, Baxter LT, Jain RK. Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: implications for therapy. Cancer Res. 1990 Aug 1; 50(15):4478-84.
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  100. Roberge S, Boucher Y, Roy PE. Transient ultrastructural variations of pulmonary lymphatic capillaries during the respiratory cycle of the rat lung. Anat Rec. 1985 Dec; 213(4):551-9.
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  101. Boucher Y, Roberge S, Roy PE. Ultrastructural comparative study on lymphatic capillaries of the subendocardium, myocardium, and subepicardium of the heart left ventricle. Microvasc Res. 1985 May; 29(3):305-19.
    View in: PubMed
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