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Robert L. Doyle, M.D., D.D.S.

TitleClinical Instructor in Psychiatry
InstitutionMassachusetts General Hospital
DepartmentPsychiatry
AddressMassachusetts General Hospital
Consult Svs., Warren 605
55 Fruit St
Boston MA 02114
Fax617/726-5946

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Hammerness P, Joshi G, Doyle R, Georgiopoulos A, Geller D, Spencer T, Petty CR, Faraone SV, Biederman J. Do stimulants reduce the risk for cigarette smoking in youth with attention-deficit hyperactivity disorder? A prospective, long-term, open-label study of extended-release methylphenidate. J Pediatr. 2013 Jan; 162(1):22-27.e2.
    View in: PubMed
  2. Surman CB, Hammerness PG, Petty C, Spencer T, Doyle R, Napolean S, Chu N, Yorks D, Biederman J. A pilot open label prospective study of memantine monotherapy in adults with ADHD. World J Biol Psychiatry. 2013 May; 14(4):291-8.
    View in: PubMed
  3. Joshi G, Petty CR, Fried R, Wozniak J, Micco JA, Henin A, Doyle R, Galdo M, Kotarski M, Caruso J, Meller B, Faraone SV, Biederman J. Discriminant and concurrent validity of a simplified DSM-based structured diagnostic instrument for the assessment of autism spectrum disorders in youth and young adults. BMC Psychiatry. 2011; 11:204.
    View in: PubMed
  4. Joshi G, Petty C, Wozniak J, Faraone SV, Doyle R, Georgiopoulos A, Hammerness P, Walls S, Glaeser B, Brethel K, Yorks D, Biederman J. A prospective open-label trial of quetiapine monotherapy in preschool and school age children with bipolar spectrum disorder. J Affect Disord. 2012 Feb; 136(3):1143-53.
    View in: PubMed
  5. Joshi G, Biederman J, Wozniak J, Doyle R, Hammerness P, Galdo M, Sullivan N, Williams C, Brethel K, Woodworth KY, Mick E. Response to second generation antipsychotics in youth with comorbid bipolar disorder and autism spectrum disorder. CNS Neurosci Ther. 2012 Jan; 18(1):28-33.
    View in: PubMed
  6. Biederman J, Mick E, Surman C, Doyle R, Hammerness P, Kotarski M, Spencer T. A randomized, 3-phase, 34-week, double-blind, long-term efficacy study of osmotic-release oral system-methylphenidate in adults with attention-deficit/hyperactivity disorder. J Clin Psychopharmacol. 2010 Oct; 30(5):549-53.
    View in: PubMed
  7. Biederman J, Petty CR, Fried R, Wozniak J, Micco JA, Henin A, Doyle R, Joshi G, Galdo M, Kotarski M, Caruso J, Yorks D, Faraone SV. Child behavior checklist clinical scales discriminate referred youth with autism spectrum disorder: a preliminary study. J Dev Behav Pediatr. 2010 Jul-Aug; 31(6):485-90.
    View in: PubMed
  8. Spencer TJ, Mick E, Surman CB, Hammerness P, Doyle R, Aleardi M, Kotarski M, Williams CG, Biederman J. A randomized, single-blind, substitution study of OROS methylphenidate (Concerta) in ADHD adults receiving immediate release methylphenidate. J Atten Disord. 2011 May; 15(4):286-94.
    View in: PubMed
  9. Biederman J, Joshi G, Mick E, Doyle R, Georgiopoulos A, Hammerness P, Kotarski M, Williams C, Wozniak J. A prospective open-label trial of lamotrigine monotherapy in children and adolescents with bipolar disorder. CNS Neurosci Ther. 2010 Apr; 16(2):91-102.
    View in: PubMed
  10. Joshi G, Wozniak J, Mick E, Doyle R, Hammerness P, Georgiopoulos A, Kotarski M, Aleardi M, Williams C, Walls S, Biederman J. A prospective open-label trial of extended-release carbamazepine monotherapy in children with bipolar disorder. J Child Adolesc Psychopharmacol. 2010 Feb; 20(1):7-14.
    View in: PubMed
  11. Surman C, Hammerness P, Petty C, Doyle R, Chu N, Gebhard N, Williams C, Biederman J. Atomoxetine in the treatment of adults with subthreshold and/or late onset attention-deficit hyperactivity disorder-not otherwise specified (ADHD-NOS): a prospective open-label 6-week study. CNS Neurosci Ther. 2010; 16(1):6-12.
    View in: PubMed
  12. Hammerness P, Georgiopoulos A, Doyle RL, Utzinger L, Schillinger M, Martelon M, Brodziak K, Biederman J, Wilens TE. An open study of adjunct OROS-methylphenidate in children who are atomoxetine partial responders: II. Tolerability and pharmacokinetics. J Child Adolesc Psychopharmacol. 2009 Oct; 19(5):493-9.
    View in: PubMed
  13. McCorry NK, Dempster M, Clarke C, Doyle R. Adjusting to life after esophagectomy: the experience of survivors and carers. Qual Health Res. 2009 Oct; 19(10):1485-94.
    View in: PubMed
  14. Wilens TE, Hammerness P, Utzinger L, Schillinger M, Georgiopoulous A, Doyle RL, Martelon M, Brodziak K. An open study of adjunct OROS-methylphenidate in children and adolescents who are atomoxetine partial responders: I. Effectiveness. J Child Adolesc Psychopharmacol. 2009 Oct; 19(5):485-92.
    View in: PubMed
  15. Hammerness P, Wilens T, Mick E, Spencer T, Doyle R, McCreary M, Becker J, Biederman J. Cardiovascular effects of longer-term, high-dose OROS methylphenidate in adolescents with attention deficit hyperactivity disorder. J Pediatr. 2009 Jul; 155(1):84-9, 89.e1.
    View in: PubMed
  16. Hammerness P, Doyle R, Kotarski M, Georgiopoulos A, Joshi G, Zeitlin S, Biederman J. Atomoxetine in children with attention-deficit hyperactivity disorder with prior stimulant therapy: a prospective open-label study. Eur Child Adolesc Psychiatry. 2009 Aug; 18(8):493-8.
    View in: PubMed
  17. Zamanian RT, Hansmann G, Snook S, Lilienfeld D, Rappaport KM, Reaven GM, Rabinovitch M, Doyle RL. Insulin resistance in pulmonary arterial hypertension. Eur Respir J. 2009 Feb; 33(2):318-24.
    View in: PubMed
  18. Theoharides TC, Doyle R. Autism, gut-blood-brain barrier, and mast cells. J Clin Psychopharmacol. 2008 Oct; 28(5):479-83.
    View in: PubMed
  19. Brams M, Mao AR, Doyle RL. Onset of efficacy of long-acting psychostimulants in pediatric attention-deficit/hyperactivity disorder. Postgrad Med. 2008 Sep; 120(3):69-88.
    View in: PubMed
  20. Theoharides TC, Doyle R, Francis K, Conti P, Kalogeromitros D. Novel therapeutic targets for autism. Trends Pharmacol Sci. 2008 Aug; 29(8):375-82.
    View in: PubMed
  21. Biederman J, Hammerness P, Doyle R, Joshi G, Aleardi M, Mick E. Risperidone treatment for ADHD in children and adolescents with bipolar disorder. Neuropsychiatr Dis Treat. 2008 Feb; 4(1):203-7.
    View in: PubMed
  22. Domizio S, Conte E, Puglielli C, Domizio R, Verrotti A, Pollice R, Casacchia M, Conti CM, Roncone R, Sabatino G, Doyle R, Barbacane RC, Conti P, Sabatino G. Epileptic EEG discharges and short non-convulsive crisis: Influence on cognitive and psychobehavioural functions in youths. Clin Invest Med. 2008; 31(1):E20-40.
    View in: PubMed
  23. Biederman J, Mick EO, Surman C, Doyle R, Hammerness P, Michel E, Martin J, Spencer TJ. Comparative acute efficacy and tolerability of OROS and immediate release formulations of methylphenidate in the treatment of adults with attention-deficit/hyperactivity disorder. BMC Psychiatry. 2007; 7:49.
    View in: PubMed
  24. Biederman J, Mick E, Spencer T, Doyle R, Joshi G, Hammerness P, Kotarski M, Aleardi M, Wozniak J. An open-label trial of aripiprazole monotherapy in children and adolescents with bipolar disorder. CNS Spectr. 2007 Sep; 12(9):683-9.
    View in: PubMed
  25. Doyle R, Mick E, Biederman J. Convergence between the Achenbach youth self-report and structured diagnostic interview diagnoses in ADHD and non-ADHD youth. J Nerv Ment Dis. 2007 Apr; 195(4):350-2.
    View in: PubMed
  26. Tumini E, Porcellini E, Chiappelli M, Conti CM, Beraudi A, Poli A, Caciagli F, Doyle R, Conti P, Licastro F. The G51S purine nucleoside phosphorylase polymorphism is associated with cognitive decline in Alzheimer's disease patients. Hum Psychopharmacol. 2007 Mar; 22(2):75-80.
    View in: PubMed
  27. Dalessandro M, Conti CM, Gambi F, Falasca K, Doyle R, Conti P, Caciagli F, Fulcheri M, Vecchiet J. Antidepressant therapy can improve adherence to antiretroviral regimens among HIV-infected and depressed patients. J Clin Psychopharmacol. 2007 Feb; 27(1):58-61.
    View in: PubMed
  28. Geller DA, Doyle R, Shaw D, Mullin B, Coffey B, Petty C, Vivas F, Biederman J. A quick and reliable screening measure for OCD in youth: reliability and validity of the obsessive compulsive scale of the Child Behavior Checklist. Compr Psychiatry. 2006 May-Jun; 47(3):234-40.
    View in: PubMed
  29. Biederman J, Mick E, Spencer T, Surman C, Hammerness P, Doyle R, Dougherty M, Aleardi M, Schweitzer K. An open-label trial of OROS methylphenidate in adults with late-onset ADHD. CNS Spectr. 2006 May; 11(5):390-6.
    View in: PubMed
  30. Doyle RL, Frazier J, Spencer TJ, Geller D, Biederman J, Wilens T. Donepezil in the treatment of ADHD-like symptoms in youths with pervasive developmental disorder: a case series. J Atten Disord. 2006 Feb; 9(3):543-9.
    View in: PubMed
  31. Biederman J, Mick E, Surman C, Doyle R, Hammerness P, Harpold T, Dunkel S, Dougherty M, Aleardi M, Spencer T. A randomized, placebo-controlled trial of OROS methylphenidate in adults with attention-deficit/hyperactivity disorder. Biol Psychiatry. 2006 May 1; 59(9):829-35.
    View in: PubMed
  32. Bersani G, Gherardelli S, Clemente R, Di Giannantonio M, Grilli A, Conti CM, Exton MS, Conti P, Doyle R, Pancheri P. Neurologic soft signs in schizophrenic patients treated with conventional and atypical antipsychotics. J Clin Psychopharmacol. 2005 Aug; 25(4):372-5.
    View in: PubMed
  33. Spencer T, Biederman J, Wilens T, Doyle R, Surman C, Prince J, Mick E, Aleardi M, Herzig K, Faraone S. A large, double-blind, randomized clinical trial of methylphenidate in the treatment of adults with attention-deficit/hyperactivity disorder. Biol Psychiatry. 2005 Mar 1; 57(5):456-63.
    View in: PubMed
  34. Coffey BJ, Biederman J, Geller D, Frazier J, Spencer T, Doyle R, Gianini L, Small A, Frisone DF, Magovcevic M, Stein N, Faraone SV. Reexamining Tic persistence and Tic-associated impairment in Tourette's Disorder: findings from a naturalistic follow-up study. J Nerv Ment Dis. 2004 Nov; 192(11):776-80.
    View in: PubMed
  35. Doyle R. The history of adult attention-deficit/hyperactivity disorder. Psychiatr Clin North Am. 2004 Jun; 27(2):203-14.
    View in: PubMed
  36. Geller DA, Biederman J, Faraone S, Spencer T, Doyle R, Mullin B, Magovcevic M, Zaman N, Farrell C. Re-examining comorbidity of Obsessive Compulsive and Attention-Deficit Hyperactivity Disorder using an empirically derived taxonomy. Eur Child Adolesc Psychiatry. 2004 Apr; 13(2):83-91.
    View in: PubMed
  37. Wilens TE, Prince JB, Spencer T, Van Patten SL, Doyle R, Girard K, Hammerness P, Goldman S, Brown S, Biederman J. An open trial of bupropion for the treatment of adults with attention-deficit/hyperactivity disorder and bipolar disorder. Biol Psychiatry. 2003 Jul 1; 54(1):9-16.
    View in: PubMed
  38. Huang SH, Gambi F, Conti F, Carratelli G, Conti CM, Mastromauro I, Riccioni G, Grilli A, Bellati U, Doyle RL. Antiepileptic drugs lower contraceptive sex hormone and increase the risk of unplanned pregnancies in women with epilepsy: revisited study. Int J Immunopathol Pharmacol. 2003 May-Aug; 16(2):181-3.
    View in: PubMed
  39. Frazier JA, Doyle R, Chiu S, Coyle JT. Treating a child with Asperger's disorder and comorbid bipolar disorder. Am J Psychiatry. 2002 Jan; 159(1):13-21.
    View in: PubMed
  40. Spencer T, Biederman J, Wilens T, Faraone S, Prince J, Gerard K, Doyle R, Parekh A, Kagan J, Bearman SK. Efficacy of a mixed amphetamine salts compound in adults with attention-deficit/hyperactivity disorder. Arch Gen Psychiatry. 2001 Aug; 58(8):775-82.
    View in: PubMed
  41. Wilens TE, Spencer TJ, Biederman J, Girard K, Doyle R, Prince J, Polisner D, Solhkhah R, Comeau S, Monuteaux MC, Parekh A. A controlled clinical trial of bupropion for attention deficit hyperactivity disorder in adults. Am J Psychiatry. 2001 Feb; 158(2):282-8.
    View in: PubMed
  42. Porta R, Doyle RL, Tatter SB, Wilens TE, Schatz RA, Sellinger OZ. The biosynthesis of polyamines in the brain of audiogenic seizure-susceptible and -resistant deermice. J Neurochem. 1981 Sep; 37(3):723-9.
    View in: PubMed
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