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Christopher Anthony Cassa, Ph.D.

TitleInstructor in Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressBrigham and Women's Hospital
HIM - Genetics
75 Francis St
Boston MA 02115
Fax617/730-0699

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Cassa CA, Tong MY, Jordan DM. Large Numbers of Genetic Variants Considered to be Pathogenic are Common in Asymptomatic Individuals. Hum Mutat. 2013 Sep; 34(9):1216-20.
    View in: PubMed
  2. Cassa CA, Chunara R, Mandl K, Brownstein JS. Twitter as a sentinel in emergency situations: lessons from the Boston marathon explosions. PLoS Curr. 2013; 5.
    View in: PubMed
  3. Cassa CA, Miller RA, Mandl KD. A novel, privacy-preserving cryptographic approach for sharing sequencing data. J Am Med Inform Assoc. 2013 Jan 1; 20(1):69-76.
    View in: PubMed
  4. Cassa CA, Savage SK, Taylor PL, Green RC, McGuire AL, Mandl KD. Disclosing pathogenic genetic variants to research participants: quantifying an emerging ethical responsibility. Genome Res. 2012 Mar; 22(3):421-8.
    View in: PubMed
  5. Tong MY, Cassa CA, Kohane IS. Automated validation of genetic variants from large databases: ensuring that variant references refer to the same genomic locations. Bioinformatics. 2011 Mar 15; 27(6):891-3.
    View in: PubMed
  6. Malin, B, Cassa C, Kantarcioglu M . Privacy-Aware Knowledge Discovery: Novel Applications and New Techniques, Chapman Hall / CRC Press. A Survey of Challenges and Solutions for Privacy in Clinical Genomics Data Mining. 2010.
  7. Cassa CA, Mandl KD. AMIA Annu Symp Proc. 2009. Risk of Re-Identification: Privacy Implications for Rare Mutation. 2009.
  8. Stoto, M. A., Dempsey, J. X., Baer, A., Cassa, C., Gibson, P. J., & Buehler, J. W. . Advances in Disease Surveillance. Expert Meeting on Privacy, Confidentiality, and Other Legal and Ethical Issues in Syndromic Surveillance. 2009; 7(2).
  9. Wieland SC, Cassa CA, Mandl KD, Berger B. Revealing the spatial distribution of a disease while preserving privacy. Proc Natl Acad Sci U S A. 2008 Nov 18; 105(46):17608-13.
    View in: PubMed
  10. Cassa CA, Kenfield S, Daniel J, Mandl KD. The Massachusetts Health and Homeland Alert Network: a scalable and secure public health knowledge management and notification system. AMIA Annu Symp Proc. 2008; 893.
    View in: PubMed
  11. Cassa CA, Wieland SC, Mandl KD. Re-identification of home addresses from spatial locations anonymized by Gaussian skew. Int J Health Geogr. 2008; 7:45.
    View in: PubMed
  12. Cassa CA, Schmidt B, Kohane IS, Mandl KD. My sister's keeper?: genomic research and the identifiability of siblings. BMC Med Genomics. 2008; 1:32.
    View in: PubMed
  13. Cassa, Christopher A. Privacy and identifiability in clinical research, personalized medicine, and public health surveillance. 2008.
  14. Cassa CA, Mandl KD. Multi-factor authentication using contents from disparate EHRs. AMIA Annu Symp Proc. 2007; 891.
    View in: PubMed
  15. Brownstein JS, Cassa CA, Kohane IS, Mandl KD. An unsupervised classification method for inferring original case locations from low-resolution disease maps. Int J Health Geogr. 2006; 5:56.
    View in: PubMed
  16. Brownstein JS, Cassa CA, Mandl KD. No place to hide--reverse identification of patients from published maps. N Engl J Med. 2006 Oct 19; 355(16):1741-2.
    View in: PubMed
  17. Grannis S, Egg J, Cassa C, Olson K, Mandl K, Overhage J . Proc Symp 2006 Syndromic Surveillance Conf, Baltimore, MD. Evaluating the Performance of a Spatial Scan Statistic Using Simulated Outbreak Characteristics. 2006.
  18. Cassa CA, Grannis SJ, Overhage JM, Mandl KD. A context-sensitive approach to anonymizing spatial surveillance data: impact on outbreak detection. J Am Med Inform Assoc. 2006 Mar-Apr; 13(2):160-5.
    View in: PubMed
  19. Cassa CA, Iancu K, Olson KL, Mandl KD. A software tool for creating simulated outbreaks to benchmark surveillance systems. BMC Med Inform Decis Mak. 2005; 5:22.
    View in: PubMed
  20. Brownstein JS, Cassa CA, Kohane IS, Mandl KD. Reverse geocoding: concerns about patient confidentiality in the display of geospatial health data. AMIA Annu Symp Proc. 2005; 905.
    View in: PubMed
  21. Grannis S, Mandl K, Olson K, Cassa C, Overhage JM . International Society of Disease Surveillance Annu Symp Proc. Boston, MA. Geographic Coordinate Transformation Methods to Reduce Privacy Risks Associated with Surveillance. 2004.
  22. Mandl KD, Reis B, Cassa C. Measuring outbreak-detection performance by using controlled feature set simulations. MMWR Morb Mortal Wkly Rep. 2004 Sep 24; 53 Suppl:130-6.
    View in: PubMed
  23. Cassa, Christopher A. Spatial outbreak detection analysis tool : a system to create sets of semi-synthetic geo-spatial clusters. 2004.
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