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Edward Patrick Ingenito, M.D.

TitleAssistant Professor of Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressBrigham and Womens Hospital
Pulmonary and Critical Care
75 Francis St
Boston MA 02115
Phone617/732-5499

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Paxson JA, Gruntman AM, Davis AM, Parkin CM, Ingenito EP, Hoffman AM. Age dependence of lung mesenchymal stromal cell dynamics following pneumonectomy. Stem Cells Dev. 2013 Dec 15; 22(24):3214-25.
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  2. Hoffman AM, Ingenito EP. Alveolar Epithelial Stem and Progenitor Cells: Emerging Evidence for their Role in Lung Regeneration. Curr Med Chem. 2012 Dec 1; 19(35):6003-8.
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  3. Valipour A, Kramer MR, Stanzel F, Kempa A, Asadi S, Fruchter O, Eberhardt R, Herth FJ, Ingenito EP. Physiological modeling of responses to upper versus lower lobe lung volume reduction in homogeneous emphysema. Front Physiol. 2012; 3:387.
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  4. Peter Y, Sen N, Levantini E, Keller S, Ingenito EP, Ciner A, Sackstein R, Shapiro SD. CD45/CD11b positive subsets of adult lung anchorage-independent cells harness epithelial stem cells in culture. J Tissue Eng Regen Med. 2013 Jul; 7(7):572-83.
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  5. Paxson JA, Gruntman A, Parkin CD, Mazan MR, Davis A, Ingenito EP, Hoffman AM. Age-dependent decline in mouse lung regeneration with loss of lung fibroblast clonogenicity and increased myofibroblastic differentiation. PLoS One. 2011; 6(8):e23232.
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  6. Hoffman AM, Paxson JA, Mazan MR, Davis AM, Tyagi S, Murthy S, Ingenito EP. Lung-derived mesenchymal stromal cell post-transplantation survival, persistence, paracrine expression, and repair of elastase-injured lung. Stem Cells Dev. 2011 Oct; 20(10):1779-92.
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  7. Herth FJ, Eberhardt R, Ingenito EP, Gompelmann D. Assessment of a novel lung sealant for performing endoscopic volume reduction therapy in patients with advanced emphysema. Expert Rev Med Devices. 2011 May; 8(3):307-12.
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  8. Ingenito EP, Tsai L, Murthy S, Tyagi S, Mazan M, Hoffman A. Autologous lung-derived mesenchymal stem cell transplantation in experimental emphysema. Cell Transplant. 2012; 21(1):175-89.
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  9. Fruchter O, Carmi U, Ingenito EP, Refaeli Y, Kramer MR. Transcutaneous carbon dioxide in severe COPD patients during bronchoscopic lung volume reduction. Respir Med. 2011 Apr; 105(4):602-7.
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  10. Simon DM, Tsai LW, Ingenito EP, Starcher BC, Mariani TJ. PPARgamma deficiency results in reduced lung elastic recoil and abnormalities in airspace distribution. Respir Res. 2010; 11:69.
    View in: PubMed
  11. Ingenito EP, Sen E, Tsai LW, Murthy S, Hoffman A. Design and testing of biological scaffolds for delivering reparative cells to target sites in the lung. J Tissue Eng Regen Med. 2010 Jun; 4(4):259-72.
    View in: PubMed
  12. Hoffman AM, Shifren A, Mazan MR, Gruntman AM, Lascola KM, Nolen-Walston RD, Kim CF, Tsai L, Pierce RA, Mecham RP, Ingenito EP. Matrix modulation of compensatory lung regrowth and progenitor cell proliferation in mice. Am J Physiol Lung Cell Mol Physiol. 2010 Feb; 298(2):L158-68.
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  13. Paxson JA, Parkin CD, Iyer LK, Mazan MR, Ingenito EP, Hoffman AM. Global gene expression patterns in the post-pneumonectomy lung of adult mice. Respir Res. 2009; 10:92.
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  14. Peter Y, Comellas A, Levantini E, Ingenito EP, Shapiro SD. Epidermal growth factor receptor and claudin-2 participate in A549 permeability and remodeling: implications for non-small cell lung cancer tumor colonization. Mol Carcinog. 2009 Jun; 48(6):488-97.
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  15. Mouded M, Egea EE, Brown MJ, Hanlon SM, Houghton AM, Tsai LW, Ingenito EP, Shapiro SD. Epithelial cell apoptosis causes acute lung injury masquerading as emphysema. Am J Respir Cell Mol Biol. 2009 Oct; 41(4):407-14.
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  16. Fessler HE, Scharf SM, Ingenito EP, McKenna RJ, Sharafkhaneh A. Physiologic basis for improved pulmonary function after lung volume reduction. Proc Am Thorac Soc. 2008 May 1; 5(4):416-20.
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  17. Ingenito EP, Wood DE, Utz JP. Bronchoscopic lung volume reduction in severe emphysema. Proc Am Thorac Soc. 2008 May 1; 5(4):454-60.
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  18. Nolen-Walston RD, Kim CF, Mazan MR, Ingenito EP, Gruntman AM, Tsai L, Boston R, Woolfenden AE, Jacks T, Hoffman AM. Cellular kinetics and modeling of bronchioalveolar stem cell response during lung regeneration. Am J Physiol Lung Cell Mol Physiol. 2008 Jun; 294(6):L1158-65.
    View in: PubMed
  19. Bellardine Black CL, Hoffman AM, Tsai LW, Ingenito EP, Suki B, Kaczka DW, Simon BA, Lutchen KR. Impact of positive end-expiratory pressure during heterogeneous lung injury: insights from computed tomographic image functional modeling. Ann Biomed Eng. 2008 Jun; 36(6):980-91.
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  20. Tsai LW, Hoffman AM, Mazan MR, Ingenito EP. Bronchoscopic measurement of collateral ventilation in a sheep model of emphysema. Respiration. 2007; 74(5):565-71.
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  21. Bellardine Black CL, Hoffman AM, Tsai LW, Ingenito EP, Suki B, Kaczka DW, Simon BA, Lutchen KR. Relationship between dynamic respiratory mechanics and disease heterogeneity in sheep lavage injury. Crit Care Med. 2007 Mar; 35(3):870-8.
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  22. Ingenito EP. Medical therapy for chronic obstructive pulmonary disease in 2007. Semin Thorac Cardiovasc Surg. 2007; 19(2):142-50.
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  23. Ingenito EP, Tsai LW. Evolving endoscopic approaches for treatment of emphysema. Semin Thorac Cardiovasc Surg. 2007; 19(2):181-9.
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  24. Lofgren JL, Mazan MR, Ingenito EP, Lascola K, Seavey M, Walsh A, Hoffman AM. Restrained whole body plethysmography for measure of strain-specific and allergen-induced airway responsiveness in conscious mice. J Appl Physiol. 2006 Nov; 101(5):1495-505.
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  25. Henderson AC, Ingenito EP, Salcedo ES, Moy ML, Reilly JJ, Lutchen KR. Dynamic lung mechanics in late-stage emphysema before and after lung volume reduction surgery. Respir Physiol Neurobiol. 2007 Mar 15; 155(3):234-42.
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  26. Simon DM, Arikan MC, Srisuma S, Bhattacharya S, Tsai LW, Ingenito EP, Gonzalez F, Shapiro SD, Mariani TJ. Epithelial cell PPAR[gamma] contributes to normal lung maturation. FASEB J. 2006 Jul; 20(9):1507-9.
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  27. Bellardine CL, Hoffman AM, Tsai L, Ingenito EP, Arold SP, Lutchen KR, Suki B. Comparison of variable and conventional ventilation in a sheep saline lavage lung injury model. Crit Care Med. 2006 Feb; 34(2):439-45.
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  28. Ingenito EP, Tsai LW, Mentzer SJ, Jaklitsch MT, Reilly JJ, Lutchen K, Mazan M, Hoffman A. Respiratory impedance following bronchoscopic or surgical lung volume reduction for emphysema. Respiration. 2005 Jul-Aug; 72(4):406-17.
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  29. Hoffman A, Tsai L, Mazan M, Bellardine C, Bell A, Lutchen K, Ingenito E. Pulmonary function tests versus computed tomography in sheep with experimental emphysema. Exp Lung Res. 2005 Jun; 31(5):497-512.
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  30. Bellardine CL, Ingenito EP, Hoffman A, Lopez F, Sanborn W, Suki B, Lutchen KR. Heterogeneous airway versus tissue mechanics and their relation to gas exchange function during mechanical ventilation. Ann Biomed Eng. 2005 May; 33(5):626-41.
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  31. Suki B, Ito S, Stamenovic D, Lutchen KR, Ingenito EP. Biomechanics of the lung parenchyma: critical roles of collagen and mechanical forces. J Appl Physiol. 2005 May; 98(5):1892-9.
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  32. Shapiro SD, Ingenito EP. The pathogenesis of chronic obstructive pulmonary disease: advances in the past 100 years. Am J Respir Cell Mol Biol. 2005 May; 32(5):367-72.
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  33. Mazan MR, Ingenito EP, Tsai L, Hoffman A. Pulmonary function tests fail to predict exercise intolerance in sheep with emphysema. Med Sci Sports Exerc. 2005 Apr; 37(4):550-6.
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  34. Miller JD, Berger RL, Malthaner RA, Celli BR, Goldsmith CH, Ingenito EP, Higgins D, Bagley P, Cox G, Wright CD. Lung volume reduction surgery vs medical treatment: for patients with advanced emphysema. Chest. 2005 Apr; 127(4):1166-77.
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  35. Seurynck SL, Brown NJ, Wu CW, Germino KW, Kohlmeir EK, Ingenito EP, Glucksberg MR, Barron AE, Johnson M. Optical monitoring of bubble size and shape in a pulsating bubble surfactometer. J Appl Physiol. 2005 Aug; 99(2):624-33.
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  36. Berger RL, Wood KA, Cabral HJ, Goodnight-White S, Ingenito EP, Gray A, Miller J, Springmeyer SC. Lung volume reduction surgery: a meta-analysis of randomized clinical trials. Treat Respir Med. 2005; 4(3):201-9.
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  37. Ingenito EP, Tsai LW, Majumdar A, Suki B. On the role of surface tension in the pathophysiology of emphysema. Am J Respir Crit Care Med. 2005 Feb 15; 171(4):300-4.
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  38. Ito S, Ingenito EP, Brewer KK, Black LD, Parameswaran H, Lutchen KR, Suki B. Mechanics, nonlinearity, and failure strength of lung tissue in a mouse model of emphysema: possible role of collagen remodeling. J Appl Physiol. 2005 Feb; 98(2):503-11.
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  39. Cavalcante FS, Ito S, Brewer K, Sakai H, Alencar AM, Almeida MP, Andrade JS, Majumdar A, Ingenito EP, Suki B. Mechanical interactions between collagen and proteoglycans: implications for the stability of lung tissue. J Appl Physiol. 2005 Feb; 98(2):672-9.
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  40. Bedenice D, Bar-Yishay E, Ingenito EP, Tsai L, Mazan MR, Hoffman AM. Evaluation of head-out constant volume body plethysmography for measurement of specific airway resistance in conscious, sedated sheep. Am J Vet Res. 2004 Sep; 65(9):1259-64.
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  41. Baron RM, Carvajal IM, Fredenburgh LE, Liu X, Porrata Y, Cullivan ML, Haley KJ, Sonna LA, De Sanctis GT, Ingenito EP, Perrella MA. Nitric oxide synthase-2 down-regulates surfactant protein-B expression and enhances endotoxin-induced lung injury in mice. FASEB J. 2004 Aug; 18(11):1276-8.
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  42. Niimi A, Matsumoto H, Amitani R, Nakano Y, Sakai H, Takemura M, Ueda T, Chin K, Itoh H, Ingenito EP, Mishima M. Effect of short-term treatment with inhaled corticosteroid on airway wall thickening in asthma. Am J Med. 2004 Jun 1; 116(11):725-31.
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  43. Ito S, Ingenito EP, Arold SP, Parameswaran H, Tgavalekos NT, Lutchen KR, Suki B. Tissue heterogeneity in the mouse lung: effects of elastase treatment. J Appl Physiol. 2004 Jul; 97(1):204-12.
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  44. Black LD, Henderson AC, Atileh H, Israel E, Ingenito EP, Lutchen KR. Relating maximum airway dilation and subsequent reconstriction to reactivity in human lungs. J Appl Physiol. 2004 May; 96(5):1808-14.
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  45. Suki B, Lutchen KR, Ingenito EP. On the progressive nature of emphysema: roles of proteases, inflammation, and mechanical forces. Am J Respir Crit Care Med. 2003 Sep 1; 168(5):516-21.
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  46. Arold SP, Suki B, Alencar AM, Lutchen KR, Ingenito EP. Variable ventilation induces endogenous surfactant release in normal guinea pigs. Am J Physiol Lung Cell Mol Physiol. 2003 Aug; 285(2):L370-5.
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  47. Brewer KK, Sakai H, Alencar AM, Majumdar A, Arold SP, Lutchen KR, Ingenito EP, Suki B. Lung and alveolar wall elastic and hysteretic behavior in rats: effects of in vivo elastase treatment. J Appl Physiol. 2003 Nov; 95(5):1926-36.
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  48. Hoffman A, Henderson AC, Tsai L, Ingenito E. Physiologic responses of sheep to two different methods of papain exposure. Inhal Toxicol. 2003 Jul; 15(8):761-80.
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  49. Henderson AC, Ingenito EP, Atileh H, Israel E, Suki B, Lutchen KR. How does airway inflammation modulate asthmatic airway constriction? An antigen challenge study. J Appl Physiol. 2003 Aug; 95(2):873-82; discussion 863.
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  50. Black LD, Dellaca R, Jung K, Atileh H, Israel E, Ingenito EP, Lutchen KR. Tracking variations in airway caliber by using total respiratory vs. airway resistance in healthy and asthmatic subjects. J Appl Physiol. 2003 Aug; 95(2):511-8.
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  51. Ingenito EP, Berger RL, Henderson AC, Reilly JJ, Tsai L, Hoffman A. Bronchoscopic lung volume reduction using tissue engineering principles. Am J Respir Crit Care Med. 2003 Mar 1; 167(5):771-8.
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  52. Ingenito EP, Loring SH, Moy ML, Mentzer SJ, Swanson SJ, Reilly JJ. Physiological characterization of variability in response to lung volume reduction surgery. J Appl Physiol. 2003 Jan; 94(1):20-30.
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  53. Karmpaliotis D, Kosmidou I, Ingenito EP, Hong K, Malhotra A, Sunday ME, Haley KJ. Angiogenic growth factors in the pathophysiology of a murine model of acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2002 Sep; 283(3):L585-95.
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  54. de Torres JP, Pinto-Plata V, Ingenito E, Bagley P, Gray A, Berger R, Celli B. Power of outcome measurements to detect clinically significant changes in pulmonary rehabilitation of patients with COPD. Chest. 2002 Apr; 121(4):1092-8.
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  55. Marzan Y, Mora R, Butler A, Butler M, Ingenito EP. Effects of simultaneous exposure of surfactant to serum proteins and free radicals. Exp Lung Res. 2002 Mar; 28(2):99-121.
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  56. Arold SP, Mora R, Lutchen KR, Ingenito EP, Suki B. Variable tidal volume ventilation improves lung mechanics and gas exchange in a rodent model of acute lung injury. Am J Respir Crit Care Med. 2002 Feb 1; 165(3):366-71.
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  57. Hunsaker AR, Ingenito EP, Reilly JJ, Costello P. Lung volume reduction surgery for emphysema: correlation of CT and V/Q imaging with physiologic mechanisms of improvement in lung function. Radiology. 2002 Feb; 222(2):491-8.
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  58. Kononov S, Brewer K, Sakai H, Cavalcante FS, Sabayanagam CR, Ingenito EP, Suki B. Roles of mechanical forces and collagen failure in the development of elastase-induced emphysema. Am J Respir Crit Care Med. 2001 Nov 15; 164(10 Pt 1):1920-6.
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  59. Sakai H, Ingenito EP, Mora R, Abbay S, Cavalcante FS, Lutchen KR, Suki B. Hysteresivity of the lung and tissue strip in the normal rat: effects of heterogeneities. J Appl Physiol. 2001 Aug; 91(2):737-47.
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  60. Berger RL, Celli BR, Meneghetti AL, Bagley PH, Wright CD, Ingenito EP, Gray A, Snider GL. Limitations of randomized clinical trials for evaluating emerging operations: the case of lung volume reduction surgery. Ann Thorac Surg. 2001 Aug; 72(2):649-57.
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  61. Lutchen KR, Jensen A, Atileh H, Kaczka DW, Israel E, Suki B, Ingenito EP. Airway constriction pattern is a central component of asthma severity: the role of deep inspirations. Am J Respir Crit Care Med. 2001 Jul 15; 164(2):207-15.
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  62. Ingenito EP, Reilly JJ, Mentzer SJ, Swanson SJ, Vin R, Keuhn H, Berger RL, Hoffman A. Bronchoscopic volume reduction: a safe and effective alternative to surgical therapy for emphysema. Am J Respir Crit Care Med. 2001 Jul 15; 164(2):295-301.
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  63. Ingenito EP, Mora R, Cullivan M, Marzan Y, Haley K, Mark L, Sonna LA. Decreased surfactant protein-B expression and surfactant dysfunction in a murine model of acute lung injury. Am J Respir Cell Mol Biol. 2001 Jul; 25(1):35-44.
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  64. Jensen A, Atileh H, Suki B, Ingenito EP, Lutchen KR. Selected contribution: airway caliber in healthy and asthmatic subjects: effects of bronchial challenge and deep inspirations. J Appl Physiol. 2001 Jul; 91(1):506-15; discussion 504-5.
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  65. Kaczka DW, Ingenito EP, Body SC, Duffy SE, Mentzer SJ, DeCamp MM, Lutchen KR. Inspiratory lung impedance in COPD: effects of PEEP and immediate impact of lung volume reduction surgery. J Appl Physiol. 2001 May; 90(5):1833-41.
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  66. Ingenito EP, Loring SH, Moy ML, Mentzer SJ, Swanson SJ, Reilly JJ. Interpreting improvement in expiratory flows after lung volume reduction surgery in terms of flow limitation theory. Am J Respir Crit Care Med. 2001 Apr; 163(5):1074-80.
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  67. Ingenito EP, Loring SH, Moy ML, Mentzer SJ, Swanson SJ, Hunsaker A, McKee CC, Reilly JJ. Comparison of physiological and radiological screening for lung volume reduction surgery. Am J Respir Crit Care Med. 2001 Apr; 163(5):1068-73.
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  68. Morris J, Ingenito EP, Mark L, Kamm RD, Johnson M. Dynamic behavior of lung surfactant. J Biomech Eng. 2001 Feb; 123(1):106-13.
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  69. Mora R, Arold S, Marzan Y, Suki B, Ingenito EP. Determinants of surfactant function in acute lung injury and early recovery. Am J Physiol Lung Cell Mol Physiol. 2000 Aug; 279(2):L342-9.
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  70. Yuan H, Kononov S, Cavalcante FS, Lutchen KR, Ingenito EP, Suki B. Effects of collagenase and elastase on the mechanical properties of lung tissue strips. J Appl Physiol. 2000 Jul; 89(1):3-14.
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  71. Ingenito EP, Mora R, Mark L. Pivotal role of anionic phospholipids in determining dynamic behavior of lung surfactant. Am J Respir Crit Care Med. 2000 Mar; 161(3 Pt 1):831-8.
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  72. Swanson SJ, Mentzer SJ, Reilly JJ, Bueno R, Lukanich JM, Jaklitsch MT, Kobzik L, Ingenito EP, Fuhlbrigge A, Donovan C, McKee C, Boyle K, Fagan GP, Sugarbaker DJ. Surveillance transbronchial lung biopsies: implication for survival after lung transplantation. J Thorac Cardiovasc Surg. 2000 Jan; 119(1):27-37.
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  73. Schochett P, Mora R, Mark L, Butler M, Ingenito EP. Calcium-dependent degradation of surfactant protein A by activated neutrophils due to serine proteases. Exp Lung Res. 1999 Oct-Nov; 25(7):595-616.
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  74. Moy ML, Loring SH, Ingenito EP, Mentzer SJ, Reilly JJ. Causes of allograft dysfunction after single lung transplantation for emphysema: extrinsic restriction versus intrinsic obstruction. Brigham and Women's Hospital Lung Transplantation Group. J Heart Lung Transplant. 1999 Oct; 18(10):986-93.
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  75. Loring SH, Leith DE, Connolly MJ, Ingenito EP, Mentzer SJ, Reilly JJ. Model of functional restriction in chronic obstructive pulmonary disease, transplantation, and lung reduction surgery. Am J Respir Crit Care Med. 1999 Sep; 160(3):821-8.
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  76. Yuan H, Westwick DT, Ingenito EP, Lutchen KR, Suki B. Parametric and nonparametric nonlinear system identification of lung tissue strip mechanics. Ann Biomed Eng. 1999 Jul-Aug; 27(4):548-62.
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  77. Ingenito EP, Mark L, Morris J, Espinosa FF, Kamm RD, Johnson M. Biophysical characterization and modeling of lung surfactant components. J Appl Physiol. 1999 May; 86(5):1702-14.
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  78. Kaczka DW, Ingenito EP, Lutchen KR. Technique to determine inspiratory impedance during mechanical ventilation: implications for flow limited patients. Ann Biomed Eng. 1999 May-Jun; 27(3):340-55.
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  79. Mark L, Ingenito EP. Surfactant function and composition after free radical exposure generated by transition metals. Am J Physiol. 1999 Mar; 276(3 Pt 1):L491-500.
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  80. Moy ML, Ingenito EP, Mentzer SJ, Evans RB, Reilly JJ. Health-related quality of life improves following pulmonary rehabilitation and lung volume reduction surgery. Chest. 1999 Feb; 115(2):383-9.
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  81. Kaczka DW, Ingenito EP, Israel E, Lutchen KR. Airway and lung tissue mechanics in asthma. Effects of albuterol. Am J Respir Crit Care Med. 1999 Jan; 159(1):169-78.
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  82. Suki B, Alencar AM, Sujeer MK, Lutchen KR, Collins JJ, Andrade JS, Ingenito EP, Zapperi S, Stanley HE. Life-support system benefits from noise. Nature. 1998 May 14; 393(6681):127-8.
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  83. Ingenito EP, Evans RB, Loring SH, Kaczka DW, Rodenhouse JD, Body SC, Sugarbaker DJ, Mentzer SJ, DeCamp MM, Reilly JJ. Relation between preoperative inspiratory lung resistance and the outcome of lung-volume-reduction surgery for emphysema. N Engl J Med. 1998 Apr 23; 338(17):1181-5.
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  84. Hunsaker A, Ingenito E, Topal U, Pugatch R, Reilly J. Preoperative screening for lung volume reduction surgery: usefulness of combining thin-section CT with physiologic assessment. AJR Am J Roentgenol. 1998 Feb; 170(2):309-14.
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  85. Yuan H, Ingenito EP, Suki B. Dynamic properties of lung parenchyma: mechanical contributions of fiber network and interstitial cells. J Appl Physiol. 1997 Nov; 83(5):1420-31; discussion 1418-9.
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  86. Swanson SJ, Mentzer SJ, DeCamp MM, Bueno R, Richards WG, Ingenito EP, Reilly JJ, Sugarbaker DJ. No-cut thoracoscopic lung plication: a new technique for lung volume reduction surgery. J Am Coll Surg. 1997 Jul; 185(1):25-32.
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  87. Kaczka DW, Ingenito EP, Suki B, Lutchen KR. Partitioning airway and lung tissue resistances in humans: effects of bronchoconstriction. J Appl Physiol. 1997 May; 82(5):1531-41.
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  88. Kennedy M, Phelps D, Ingenito E. Mechanisms of surfactant dysfunction in early acute lung injury. Exp Lung Res. 1997 May-Jun; 23(3):171-89.
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  89. Hirsch DR, Ingenito EP, Goldhaber SZ. Prevalence of deep venous thrombosis among patients in medical intensive care. JAMA. 1995 Jul 26; 274(4):335-7.
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  90. Ingenito EP, Mark L, Lilly C, Davison B. Autonomic regulation of tissue resistance in the guinea pig lung. J Appl Physiol. 1995 Apr; 78(4):1382-7.
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  91. Otis DR, Ingenito EP, Kamm RD, Johnson M. Dynamic surface tension of surfactant TA: experiments and theory. J Appl Physiol. 1994 Dec; 77(6):2681-8.
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  92. Ingenito EP, Mark L, Davison B. Effects of acute lung injury on dynamic tissue properties. J Appl Physiol. 1994 Dec; 77(6):2689-97.
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  93. Keane MG, Ingenito EP, Goldhaber SZ. Utilization of venous thromboembolism prophylaxis in the medical intensive care unit. Chest. 1994 Jul; 106(1):13-4.
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  94. Ingenito EP, Kennedy M. Amplitude-modulated ventilation. Effects in acute lung injury and characterization of mechanisms of action. Chest. 1994 Mar; 105(3 Suppl):63S-66S.
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  95. Ingenito EP, Davison B, Fredberg JJ. Tissue resistance in the guinea pig at baseline and during methacholine constriction. J Appl Physiol. 1993 Dec; 75(6):2541-8.
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  96. Fredberg JJ, Bunk D, Ingenito E, Shore SA. Tissue resistance and the contractile state of lung parenchyma. J Appl Physiol. 1993 Mar; 74(3):1387-97.
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  97. Davison B, Gumowitz J, Ingenito E. Development and testing of a PC-based system with menu-driven software for evaluating lung function in ICU patients. Comput Biol Med. 1992 Nov; 22(6):423-36.
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  98. Ingenito EP, Godleski JJ, Pliss LB, Pichurko BM, Ingram RH. Relationship among mediators, inflammation, and volume history with antigen versus hyperpnea challenge in guinea pigs. Am Rev Respir Dis. 1992 Nov; 146(5 Pt 1):1315-9.
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  99. Ingenito EP, Pliss LB, Martins MA, Ingram RH. Effects of capsaicin on mechanical, cellular, and mediator responses to antigen in sensitized guinea pigs. Am Rev Respir Dis. 1991 Mar; 143(3):572-7.
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  100. Pliss LB, Ingenito EP, Ingram RH. Baseline lung function and inflammatory indices in guinea pigs: effects of growth, repeated lavage, and orotracheal intubation. Exp Lung Res. 1990 Nov-Dec; 16(6):617-26.
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  101. Pliss LB, Ingenito EP, Ingram RH, Pichurko B. Assessment of bronchoalveolar cell and mediator response to isocapnic hyperpnea in asthma. Am Rev Respir Dis. 1990 Jul; 142(1):73-8.
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  102. Ingenito EP, Pliss LB, Ingram RH, Pichurko BM. Bronchoalveolar lavage cell and mediator responses to hyperpnea-induced bronchoconstriction in the guinea pig. Am Rev Respir Dis. 1990 May; 141(5 Pt 1):1162-6.
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  103. Wang YT, Thompson LM, Ingenito EP, Ingram RH. Effects of increasing doses of beta-agonists on airway and parenchymal hysteresis. J Appl Physiol. 1990 Jan; 68(1):363-8.
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  104. Ingenito EP, Pichurko BM, Lafleur J, Drazen JM, Ingram RH, Solway J. Breathing pattern affects respiratory heat loss but not bronchoconstrictor response in asthma. Lung. 1990; 168(1):23-34.
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  105. Lim TK, Ang SM, Rossing TH, Ingenito EP, Ingram RH. The effects of deep inhalation on maximal expiratory flow during intensive treatment of spontaneous asthmatic episodes. Am Rev Respir Dis. 1989 Aug; 140(2):340-3.
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  106. Ray DW, Ingenito EP, Strek M, Schumacker PT, Solway J. Longitudinal distribution of canine respiratory heat and water exchanges. J Appl Physiol. 1989 Jun; 66(6):2788-98.
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  107. Pliss LB, Ingenito EP, Ingram RH. Responsiveness, inflammation, and effects of deep breaths on obstruction in mild asthma. J Appl Physiol. 1989 May; 66(5):2298-304.
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  108. Ingenito EP, Ingram RH. Early and late-phase bronchoconstriction after allergen challenge of nonanesthetized guinea pigs. Am Rev Respir Dis. 1989 Feb; 139(2):569.
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  109. Kariya ST, Thompson LM, Ingenito EP, Ingram RH. Effects of lung volume, volume history, and methacholine on lung tissue viscance. J Appl Physiol. 1989 Feb; 66(2):977-82.
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  110. Ingenito E, Solway J, Lafleur J, Lombardo A, Drazen JM, Pichurko B. Dissociation of temperature-gradient and evaporative heat loss during cold gas hyperventilation in cold-induced asthma. Am Rev Respir Dis. 1988 Sep; 138(3):540-6.
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  111. Ingenito E, Kamm RD, Watson JW, Slutsky AS. A model of constant-flow ventilation in a dog lung. J Appl Physiol. 1988 May; 64(5):2150-9.
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  112. Ingenito EP, Solway J, McFadden ER, Pichurko B, Bowman HF, Michaels D, Drazen JM. Indirect assessment of mucosal surface temperatures in the airways: theory and tests. J Appl Physiol. 1987 Nov; 63(5):2075-83.
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  113. Watson J, Kamm RD, Burwen DR, Brown R, Ingenito E, Slutsky AS. Gas exchange during constant flow ventilation with different gases. Am Rev Respir Dis. 1987 Aug; 136(2):420-5.
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  114. Ingenito EP, Solway J, McFadden ER, Pichurko BM, Cravalho EG, Drazen JM. Finite difference analysis of respiratory heat transfer. J Appl Physiol. 1986 Dec; 61(6):2252-9.
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  115. Solway J, Leff AR, Dreshaj I, Munoz NM, Ingenito EP, Michaels D, Ingram RH, Drazen JM. Circulatory heat sources for canine respiratory heat exchange. J Clin Invest. 1986 Oct; 78(4):1015-9.
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  116. Solway J, Pichurko BM, Ingenito EP, McFadden ER, Fanta CH, Ingram RH, Drazen JM. Breathing pattern affects airway wall temperature during cold air hyperpnea in humans. Am Rev Respir Dis. 1985 Oct; 132(4):853-7.
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  117. McFadden ER, Pichurko BM, Bowman HF, Ingenito E, Burns S, Dowling N, Solway J. Thermal mapping of the airways in humans. J Appl Physiol. 1985 Feb; 58(2):564-70.
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  118. Strauss G, Ingenito EP. Stabilization of liposome bilayers to freezing and thawing: effects of cryoprotective agents and membrane proteins. Cryobiology. 1980 Oct; 17(5):508-15.
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