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Last Name
Institution

Amy Jo Wagers, Ph.D.

TitleProfessor of Stem Cell and Regenerative Biology
InstitutionFaculty of Arts & Sciences
DepartmentStem Cell and Regenerative Biology
AddressSection on Developmental and Stem Cell Biology
Joslin Diabetes Center, Room 620C
One Joslin Place
Boston MA 02215
Phone617/496-3046
Fax617/732-2593

 Mentoring 
 completed student projects
Investigation into Heterotypic Cell Fusion between Muscle and Hematopoietic Cells
Summer, 05/23/05 - 09/02/05

 Research 
 research resources
This researcher has shared information about their research resources
in the eagle-i Network. To update or add resource records, contact
eagle-i@hms.harvard.edu.
Flow Cytometry Core (JDC) - Core services (9), Instruments (7) and Software (2)

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Kikuchi K, Hettmer S, Aslam MI, Michalek JE, Laub W, Wilky BA, Loeb DM, Rubin BP, Wagers AJ, Keller C. Cell-cycle dependent expression of a translocation-mediated fusion oncogene mediates checkpoint adaptation in rhabdomyosarcoma. PLoS Genet. 2014 Jan; 10(1):e1004107.
    View in: PubMed
  2. Burzyn D, Kuswanto W, Kolodin D, Shadrach JL, Cerletti M, Jang Y, Sefik E, Tan TG, Wagers AJ, Benoist C, Mathis D. A special population of regulatory T cells potentiates muscle repair. Cell. 2013 Dec 5; 155(6):1282-95.
    View in: PubMed
  3. Xu C, Tabebordbar M, Iovino S, Ciarlo C, Liu J, Castiglioni A, Price E, Liu M, Barton ER, Kahn CR, Wagers AJ, Zon LI. A Zebrafish Embryo Culture System Defines Factors that Promote Vertebrate Myogenesis across Species. Cell. 2013 Nov 7; 155(4):909-21.
    View in: PubMed
  4. Teo AK, Wagers AJ, Kulkarni RN. New opportunities: harnessing induced pluripotency for discovery in diabetes and metabolism. Cell Metab. 2013 Dec 3; 18(6):775-91.
    View in: PubMed
  5. Zangi L, Lui KO, von Gise A, Ma Q, Ebina W, Ptaszek LM, Später D, Xu H, Tabebordbar M, Gorbatov R, Sena B, Nahrendorf M, Briscoe DM, Li RA, Wagers AJ, Rossi DJ, Pu WT, Chien KR. Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction. Nat Biotechnol. 2013 Oct; 31(10):898-907.
    View in: PubMed
  6. Hettmer S, Teot LA, van Hummelen P, Macconaill L, Bronson RT, Dall'osso C, Mao J, McMahon AP, Gruber PJ, Grier HE, Rodriguez-Galindo C, Fletcher CD, Wagers AJ. Mutations in Hedgehog pathway genes in fetal rhabdomyomas. J Pathol. 2013 Sep; 231(1):44-52.
    View in: PubMed
  7. Gazit R, Garrison BS, Rao TN, Shay T, Costello J, Ericson J, Kim F, Collins JJ, Regev A, Wagers AJ, Rossi DJ. Transcriptome analysis identifies regulators of hematopoietic stem and progenitor cells. Stem Cell Reports. 2013; 1(3):266-80.
    View in: PubMed
  8. Aslam MI, Hettmer S, Abraham J, Latocha D, Soundararajan A, Huang ET, Goros MW, Michalek JE, Wang S, Mansoor A, Druker BJ, Wagers AJ, Tyner JW, Keller C. Dynamic and Nuclear Expression of PDGFRa and IGF-1R in Alveolar Rhabdomyosarcoma. Mol Cancer Res. 2013 Nov; 11(11):1303-13.
    View in: PubMed
  9. Miron VE, Boyd A, Zhao JW, Yuen TJ, Ruckh JM, Shadrach JL, van Wijngaarden P, Wagers AJ, Williams A, Franklin RJ, Ffrench-Constant C. M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination. Nat Neurosci. 2013 Sep; 16(9):1211-8.
    View in: PubMed
  10. Schepers K, Pietras EM, Reynaud D, Flach J, Binnewies M, Garg T, Wagers AJ, Hsiao EC, Passegué E. Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche. Cell Stem Cell. 2013 Sep 5; 13(3):285-99.
    View in: PubMed
  11. Loffredo FS, Steinhauser ML, Jay SM, Gannon J, Pancoast JR, Yalamanchi P, Sinha M, Dall'osso C, Khong D, Shadrach JL, Miller CM, Singer BS, Stewart A, Psychogios N, Gerszten RE, Hartigan AJ, Kim MJ, Serwold T, Wagers AJ, Lee RT. Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy. Cell. 2013 May 9; 153(4):828-39.
    View in: PubMed
  12. Mingueneau M, Kreslavsky T, Gray D, Heng T, Cruse R, Ericson J, Bendall S, Spitzer MH, Nolan GP, Kobayashi K, von Boehmer H, Mathis D, Benoist C, Best AJ, Knell J, Goldrath A, Jojic V, Koller D, Shay T, Regev A, Cohen N, Brennan P, Brenner M, Kim F, Rao TN, Wagers A, Heng T, Ericson J, Rothamel K, Ortiz-Lopez A, Mathis D, Benoist C, Bezman NA, Sun JC, Min-Oo G, Kim CC, Lanier LL, Miller J, Brown B, Merad M, Gautier EL, Jakubzick C, Randolph GJ, Monach P, Blair DA, Dustin ML, Shinton SA, Hardy RR, Laidlaw D, Collins J, Gazit R, Rossi DJ, Malhotra N, Sylvia K, Kang J, Kreslavsky T, Fletcher A, Elpek K, Bellemare-Pelletier A, Malhotra D, Turley S. The transcriptional landscape of aß T cell differentiation. Nat Immunol. 2013 Jun; 14(6):619-32.
    View in: PubMed
  13. Jojic V, Shay T, Sylvia K, Zuk O, Sun X, Kang J, Regev A, Koller D, Best AJ, Knell J, Goldrath A, Jojic V, Koller D, Shay T, Regev A, Cohen N, Brennan P, Brenner M, Kim F, Rao TN, Wagers A, Heng T, Ericson J, Rothamel K, Ortiz-Lopez A, Mathis D, Benoist C, Bezman NA, Sun JC, Min-Oo G, Kim CC, Lanier LL, Miller J, Brown B, Merad M, Gautier EL, Jakubzick C, Randolph GJ, Monach P, Blair DA, Dustin ML, Shinton SA, Hardy RR, Laidlaw D, Collins J, Gazit R, Rossi DJ, Malhotra N, Sylvia K, Kang J, Kreslavsky T, Fletcher A, Elpek K, Bellemare-Pelletier A, Malhotra D, Turley S. Identification of transcriptional regulators in the mouse immune system. Nat Immunol. 2013 Jun; 14(6):633-43.
    View in: PubMed
  14. Le X, Pugach EK, Hettmer S, Storer NY, Liu J, Wills AA, Dibiase A, Chen EY, Ignatius MS, Poss KD, Wagers AJ, Langenau DM, Zon LI. A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development. Development. 2013 Jun; 140(11):2354-64.
    View in: PubMed
  15. Nabors LK, Wang LD, Wagers AJ, Kansas GS. Overlapping roles for endothelial selectins in murine hematopoietic stem/progenitor cell homing to bone marrow. Exp Hematol. 2013 Jul; 41(7):588-96.
    View in: PubMed
  16. Best JA, Blair DA, Knell J, Yang E, Mayya V, Doedens A, Dustin ML, Goldrath AW, Monach P, Shinton SA, Hardy RR, Jianu R, Koller D, Collins J, Gazit R, Garrison BS, Rossi DJ, Narayan K, Sylvia K, Kang J, Fletcher A, Elpek K, Bellemare-Pelletier A, Malhotra D, Turley S, Best JA, Knell J, Goldrath AW, Jojic V, Koller D, Shay T, Regev A, Cohen N, Brennan P, Brenner M, Kreslavsky T, Bezman NA, Sun JC, Kim CC, Lanier LL, Miller J, Brown B, Merad M, Gautier EL, Jakubzick C, Randolph GJ, Kim F, Rao TN, Wagers A, Heng T, Painter M, Ericson J, Davis S, Ergun A, Mingueneau M, Mathis D, Benoist C. Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation. Nat Immunol. 2013 Apr; 14(4):404-12.
    View in: PubMed
  17. El Ouaamari A, Kawamori D, Dirice E, Liew CW, Shadrach JL, Hu J, Katsuta H, Hollister-Lock J, Qian WJ, Wagers AJ, Kulkarni RN. Liver-Derived Systemic Factors Drive ß Cell Hyperplasia in Insulin-Resistant States. Cell Rep. 2013 Feb 21; 3(2):401-10.
    View in: PubMed
  18. Cohen NR, Brennan PJ, Shay T, Watts GF, Brigl M, Kang J, Brenner MB, Monach P, Shinton SA, Hardy RR, Jianu R, Koller D, Collins J, Gazit R, Garrison BS, Rossi DJ, Narayan K, Sylvia K, Kang J, Fletcher A, Elpek K, Bellemare-Pelletier A, Malhotra D, Turley S, Best AJ, Knell J, Goldrath A, Jojic V, Koller D, Shay T, Regev A, Cohen N, Brennan P, Brenner M, Kreslavsky T, Bezman NA, Sun JC, Kim CC, Lanier LL, Miller J, Brown B, Merad M, Gautier EL, Jakubzick C, Randolph GJ, Kim F, Rao TN, Wagers A, Heng T, Painter M, Ericson J, Davis S, Ergun A, Mingueneau M, Mathis D, Benoist C. Shared and distinct transcriptional programs underlie the hybrid nature of iNKT cells. Nat Immunol. 2013 Jan; 14(1):90-9.
    View in: PubMed
  19. Tabebordbar M, Wang ET, Wagers AJ. Skeletal muscle degenerative diseases and strategies for therapeutic muscle repair. Annu Rev Pathol. 2013 Jan 24; 8:441-75.
    View in: PubMed
  20. Liu J, Hettmer S, Milsom MD, Hofmann I, Hua F, Miller C, Bronson RT, Wagers AJ. Induction of histiocytic sarcoma in mouse skeletal muscle. PLoS One. 2012; 7(8):e44044.
    View in: PubMed
  21. Hayhurst M, Wagner AK, Cerletti M, Wagers AJ, Rubin LL. A cell-autonomous defect in skeletal muscle satellite cells expressing low levels of survival of motor neuron protein. Dev Biol. 2012 Aug 15; 368(2):323-34.
    View in: PubMed
  22. Gottumukkala RV, Lv H, Cornivelli L, Wagers AJ, Kwong RY, Bronson R, Stewart GC, Schulze PC, Chutkow W, Wolpert HA, Lee RT, Lipes MA. Myocardial infarction triggers chronic cardiac autoimmunity in type 1 diabetes. Sci Transl Med. 2012 Jun 13; 4(138):138ra80.
    View in: PubMed
  23. Cerletti M, Jang YC, Finley LW, Haigis MC, Wagers AJ. Short-term calorie restriction enhances skeletal muscle stem cell function. Cell Stem Cell. 2012 May 4; 10(5):515-9.
    View in: PubMed
  24. Wagers AJ. The stem cell niche in regenerative medicine. Cell Stem Cell. 2012 Apr 6; 10(4):362-9.
    View in: PubMed
  25. Jiang X, Clark RA, Liu L, Wagers AJ, Fuhlbrigge RC, Kupper TS. Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity. Nature. 2012 Mar 8; 483(7388):227-31.
    View in: PubMed
  26. Gibney BC, Chamoto K, Lee GS, Simpson DC, Miele LF, Tsuda A, Konerding MA, Wagers A, Mentzer SJ. Cross-circulation and cell distribution kinetics in parabiotic mice. J Cell Physiol. 2012 Feb; 227(2):821-8.
    View in: PubMed
  27. Ruckh JM, Zhao JW, Shadrach JL, van Wijngaarden P, Rao TN, Wagers AJ, Franklin RJ. Rejuvenation of regeneration in the aging central nervous system. Cell Stem Cell. 2012 Jan 6; 10(1):96-103.
    View in: PubMed
  28. Hettmer S, Liu J, Miller CM, Lindsay MC, Sparks CA, Guertin DA, Bronson RT, Langenau DM, Wagers AJ. Sarcomas induced in discrete subsets of prospectively isolated skeletal muscle cells. Proc Natl Acad Sci U S A. 2011 Dec 13; 108(50):20002-7.
    View in: PubMed
  29. Tan KY, Eminli S, Hettmer S, Hochedlinger K, Wagers AJ. Efficient generation of iPS cells from skeletal muscle stem cells. PLoS One. 2011; 6(10):e26406.
    View in: PubMed
  30. Jang YC, Sinha M, Cerletti M, Dall'osso C, Wagers AJ. Skeletal muscle stem cells: effects of aging and metabolism on muscle regenerative function. Cold Spring Harb Symp Quant Biol. 2011; 76:101-11.
    View in: PubMed
  31. Wang LD, Wagers AJ. Dynamic niches in the origination and differentiation of haematopoietic stem cells. Nat Rev Mol Cell Biol. 2011 Oct; 12(10):643-55.
    View in: PubMed
  32. Shadrach JL, Wagers AJ. Stem cells for skeletal muscle repair. Philos Trans R Soc Lond B Biol Sci. 2011 Aug 12; 366(1575):2297-306.
    View in: PubMed
  33. Woo M, Isganaitis E, Cerletti M, Fitzpatrick C, Wagers AJ, Jimenez-Chillaron J, Patti ME. Early life nutrition modulates muscle stem cell number: implications for muscle mass and repair. Stem Cells Dev. 2011 Oct; 20(10):1763-9.
    View in: PubMed
  34. Schulz TJ, Huang TL, Tran TT, Zhang H, Townsend KL, Shadrach JL, Cerletti M, McDougall LE, Giorgadze N, Tchkonia T, Schrier D, Falb D, Kirkland JL, Wagers AJ, Tseng YH. Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat. Proc Natl Acad Sci U S A. 2011 Jan 4; 108(1):143-8.
    View in: PubMed
  35. Wagers A. Delivering on a promise. Interviewed by Kristie Nybo. Biotechniques. 2010 Aug; 49(2):545.
    View in: PubMed
  36. Polo JM, Liu S, Figueroa ME, Kulalert W, Eminli S, Tan KY, Apostolou E, Stadtfeld M, Li Y, Shioda T, Natesan S, Wagers AJ, Melnick A, Evans T, Hochedlinger K. Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells. Nat Biotechnol. 2010 Aug; 28(8):848-55.
    View in: PubMed
  37. Young AP, Wagers AJ. Pax3 induces differentiation of juvenile skeletal muscle stem cells without transcriptional upregulation of canonical myogenic regulatory factors. J Cell Sci. 2010 Aug 1; 123(Pt 15):2632-9.
    View in: PubMed
  38. Taylor PL, Barker RA, Blume KG, Cattaneo E, Colman A, Deng H, Edgar H, Fox IJ, Gerstle C, Goldstein LS, High KA, Lyall A, Parkman R, Pitossi FJ, Prentice ED, Rooke HM, Sipp DA, Srivastava A, Stayn S, Steinberg GK, Wagers AJ, Weissman IL. Patients beware: commercialized stem cell treatments on the web. Cell Stem Cell. 2010 Jul 2; 7(1):43-9.
    View in: PubMed
  39. Song G, Nguyen DT, Pietramaggiori G, Scherer S, Chen B, Zhan Q, Ogawa R, Yannas IV, Wagers AJ, Orgill DP, Murphy GF. Use of the parabiotic model in studies of cutaneous wound healing to define the participation of circulating cells. Wound Repair Regen. 2010 Jul-Aug; 18(4):426-32.
    View in: PubMed
  40. Rask-Madsen C, Li Q, Freund B, Feather D, Abramov R, Wu IH, Chen K, Yamamoto-Hiraoka J, Goldenbogen J, Sotiropoulos KB, Clermont A, Geraldes P, Dall'Osso C, Wagers AJ, Huang PL, Rekhter M, Scalia R, Kahn CR, King GL. Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice. Cell Metab. 2010 May 5; 11(5):379-89.
    View in: PubMed
  41. Hettmer S, Wagers AJ. Muscling in: Uncovering the origins of rhabdomyosarcoma. Nat Med. 2010 Feb; 16(2):171-3.
    View in: PubMed
  42. Mayack SR, Shadrach JL, Kim FS, Wagers AJ. Systemic signals regulate ageing and rejuvenation of blood stem cell niches. Nature. 2010 Jan 28; 463(7280):495-500.
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  43. Forsberg EC, Passegué E, Prohaska SS, Wagers AJ, Koeva M, Stuart JM, Weissman IL. Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells. PLoS One. 2010; 5(1):e8785.
    View in: PubMed
  44. Schemionek M, Elling C, Steidl U, Bäumer N, Hamilton A, Spieker T, Göthert JR, Stehling M, Wagers A, Huettner CS, Tenen DG, Tickenbrock L, Berdel WE, Serve H, Holyoake TL, Müller-Tidow C, Koschmieder S. BCR-ABL enhances differentiation of long-term repopulating hematopoietic stem cells. Blood. 2010 Apr 22; 115(16):3185-95.
    View in: PubMed
  45. Conboy MJ, Cerletti M, Wagers AJ, Conboy IM. Immuno-analysis and FACS sorting of adult muscle fiber-associated stem/precursor cells. Methods Mol Biol. 2010; 621:165-73.
    View in: PubMed
  46. Liu J, Sato C, Cerletti M, Wagers A. Notch signaling in the regulation of stem cell self-renewal and differentiation. Curr Top Dev Biol. 2010; 92:367-409.
    View in: PubMed
  47. Guibal FC, Alberich-Jorda M, Hirai H, Ebralidze A, Levantini E, Di Ruscio A, Zhang P, Santana-Lemos BA, Neuberg D, Wagers AJ, Rego EM, Tenen DG. Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia. Blood. 2009 Dec 24; 114(27):5415-25.
    View in: PubMed
  48. Kumar D, Shadrach JL, Wagers AJ, Lassar AB. Id3 is a direct transcriptional target of Pax7 in quiescent satellite cells. Mol Biol Cell. 2009 Jul; 20(14):3170-7.
    View in: PubMed
  49. Pietramaggiori G, Scherer SS, Alperovich M, Chen B, Orgill DP, Wagers AJ. Improved cutaneous healing in diabetic mice exposed to healthy peripheral circulation. J Invest Dermatol. 2009 Sep; 129(9):2265-74.
    View in: PubMed
  50. Cerletti M, Shadrach JL, Jurga S, Sherwood R, Wagers AJ. Regulation and function of skeletal muscle stem cells. Cold Spring Harb Symp Quant Biol. 2008; 73:317-22.
    View in: PubMed
  51. Breault DT, Min IM, Carlone DL, Farilla LG, Ambruzs DM, Henderson DE, Algra S, Montgomery RK, Wagers AJ, Hole N. Generation of mTert-GFP mice as a model to identify and study tissue progenitor cells. Proc Natl Acad Sci U S A. 2008 Jul 29; 105(30):10420-5.
    View in: PubMed
  52. Cerletti M, Jurga S, Witczak CA, Hirshman MF, Shadrach JL, Goodyear LJ, Wagers AJ. Highly efficient, functional engraftment of skeletal muscle stem cells in dystrophic muscles. Cell. 2008 Jul 11; 134(1):37-47.
    View in: PubMed
  53. Cao YA, Wagers AJ, Karsunky H, Zhao H, Reeves R, Wong RJ, Stevenson DK, Weissman IL, Contag CH. Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors. Blood. 2008 Dec 1; 112(12):4494-502.
    View in: PubMed
  54. Mayack SR, Wagers AJ. Osteolineage niche cells initiate hematopoietic stem cell mobilization. Blood. 2008 Aug 1; 112(3):519-31.
    View in: PubMed
  55. Min IM, Pietramaggiori G, Kim FS, Passegué E, Stevenson KE, Wagers AJ. The transcription factor EGR1 controls both the proliferation and localization of hematopoietic stem cells. Cell Stem Cell. 2008 Apr 10; 2(4):380-91.
    View in: PubMed
  56. Jakubzick C, Tacke F, Ginhoux F, Wagers AJ, van Rooijen N, Mack M, Merad M, Randolph GJ. Blood monocyte subsets differentially give rise to CD103+ and CD103- pulmonary dendritic cell populations. J Immunol. 2008 Mar 1; 180(5):3019-27.
    View in: PubMed
  57. Laird DJ, von Andrian UH, Wagers AJ. Stem cell trafficking in tissue development, growth, and disease. Cell. 2008 Feb 22; 132(4):612-30.
    View in: PubMed
  58. Wagers AJ. Wnt not, waste not. Cell Stem Cell. 2008 Jan 10; 2(1):6-7.
    View in: PubMed
  59. Jones DL, Wagers AJ. No place like home: anatomy and function of the stem cell niche. Nat Rev Mol Cell Biol. 2008 Jan; 9(1):11-21.
    View in: PubMed
  60. Massberg S, Schaerli P, Knezevic-Maramica I, Köllnberger M, Tubo N, Moseman EA, Huff IV, Junt T, Wagers AJ, Mazo IB, von Andrian UH. Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues. Cell. 2007 Nov 30; 131(5):994-1008.
    View in: PubMed
  61. Monach PA, Verschoor A, Jacobs JP, Carroll MC, Wagers AJ, Benoist C, Mathis D. Circulating C3 is necessary and sufficient for induction of autoantibody-mediated arthritis in a mouse model. Arthritis Rheum. 2007 Sep; 56(9):2968-74.
    View in: PubMed
  62. Sherwood RI, Wagers AJ, Weissman IL. Isolation and characterization of muscle regenerating cells(pending). 2007.
  63. Monach PA, Verschoor A, Jacobs JP, Carroll MC, Wagers AJ, Benoist C, Mathis D. Circulating C3 is necessary and sufficient for autoantibody-mediated arthritis. Arthritis & Rheumatism. 2007.
  64. Wagers AJ, Min IM. Enhancing stem cell mobilization (pending). 2007.
  65. Bogunovic M, Ginhoux F, Wagers A, Loubeau M, Isola LM, Lubrano L, Najfeld V, Phelps RG, Grosskreutz C, Scigliano E, Frenette PS, Merad M. Identification of a radio-resistant and cycling dermal dendritic cell population in mice and men. J Exp Med. 2006 Nov 27; 203(12):2627-38.
    View in: PubMed
  66. Santarelli JG, Udani V, Yung YC, Cheshier S, Wagers A, Brekken RA, Weissman I, Tse V. Incorporation of bone marrow-derived Flk-1-expressing CD34+ cells in the endothelium of tumor vessels in the mouse brain. Neurosurgery. 2006 Aug; 59(2):374-82; discussion 374-82.
    View in: PubMed
  67. Wagers, AJ. Podcast Special: Stem Cells. 2006.
  68. Eggan K, Jurga S, Gosden R, Min IM, Wagers AJ. Ovulated oocytes in adult mice derive from non-circulating germ cells. Nature. 2006 Jun 29; 441(7097):1109-14.
    View in: PubMed
  69. Sherwood RI, Wagers AJ. Harnessing the potential of myogenic satellite cells. Trends Mol Med. 2006 May; 12(5):189-92.
    View in: PubMed
  70. Passegué E, Wagers AJ. Regulating quiescence: new insights into hematopoietic stem cell biology. Dev Cell. 2006 Apr; 10(4):415-7.
    View in: PubMed
  71. Bogunovic M, Ginhoux F, Wagers A, Loubeau M, Isola LM, Lubrano L, Najfeld V, Phelps RG, Grosskreutz C, Scigliano E, Frenette P, Merad M. Identification of a cycling and radio-resistant dendritic cell population in mouse and human dermis: potential impact on graft versus host disease. Journal of Experimental Medicine. 2006; 203:2627-38.
  72. Wagers AJ, Weissman IL. Differential expression of alpha2 integrin separates long-term and short-term reconstituting Lin-/loThy1.1(lo)c-kit+ Sca-1+ hematopoietic stem cells. Stem Cells. 2006 Apr; 24(4):1087-94.
    View in: PubMed
  73. Passegué E, Wagers AJ, Giuriato S, Anderson WC, Weissman IL. Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates. J Exp Med. 2005 Dec 5; 202(11):1599-611.
    View in: PubMed
  74. Udani VM, Santarelli JG, Yung YC, Wagers AJ, Cheshier SH, Weissman IL, Tse V. Hematopoietic stem cells give rise to perivascular endothelial-like cells during brain tumor angiogenesis. Stem Cells Dev. 2005 Oct; 14(5):478-86.
    View in: PubMed
  75. Wagers AJ, Conboy IM. Cellular and molecular signatures of muscle regeneration: current concepts and controversies in adult myogenesis. Cell. 2005 Sep 9; 122(5):659-67.
    View in: PubMed
  76. Surdez D, Kunz B, Wagers AJ, Weissman IL, Terskikh AV. Simple and efficient isolation of hematopoietic stem cells from H2K-zFP transgenic mice. Stem Cells. 2005 Nov-Dec; 23(10):1617-25.
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  77. Wagers AJ. Stem cell grand SLAM. Cell. 2005 Jul 1; 121(7):967-70.
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  78. Rossi DJ, Bryder D, Zahn JM, Ahlenius H, Sonu R, Wagers AJ, Weissman IL. Cell intrinsic alterations underlie hematopoietic stem cell aging. Proc Natl Acad Sci U S A. 2005 Jun 28; 102(26):9194-9.
    View in: PubMed
  79. Massengale M, Wagers AJ, Vogel H, Weissman IL. Hematopoietic cells maintain hematopoietic fates upon entering the brain. J Exp Med. 2005 May 16; 201(10):1579-89.
    View in: PubMed
  80. Conboy IM, Conboy MJ, Wagers AJ, Girma ER, Weissman IL, Rando TA. Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature. 2005 Feb 17; 433(7027):760-4.
    View in: PubMed
  81. Santarelli JG, Udani V, Yung CY, Cheshier S, Wagers A, Brekken RA, Weissman I, Tse V. Preuss Resident Research Award: bone marrow-derived Flk-1-expressing CD34+ cells contribute to the endothelium of tumor vessels in mouse brain. Clin Neurosurg. 2005; 52:384-8.
    View in: PubMed
  82. Rossi DJ, Bryder D, Zahn JM, Ahlenius H, Sonu R, Wagers AJ, Weissman IL. Cell intrinsic alterations underlie hematopoietic stem cells aging. Proceeding of the National Academy of Science USA. 2005; 102:9194-99.
  83. Domen J, Wagers A, Weissman IL. Hematopoietic stem cells. In Stem Cells: Scientific Progress and Future Research Directions. Department of Health and Human Services. 2005.
  84. Yung YC, Cheshier S, Santarelli JG, Huang Z, Wagers A, Weissman I, Tse V. Incorporation of naive bone marrow derived cells into the vascular architecture of brain tumor. Microcirculation. 2004 Dec; 11(8):699-708.
    View in: PubMed
  85. Sherwood RI, Christensen JL, Conboy IM, Conboy MJ, Rando TA, Weissman IL, Wagers AJ. Isolation of adult mouse myogenic progenitors: functional heterogeneity of cells within and engrafting skeletal muscle. Cell. 2004 Nov 12; 119(4):543-54.
    View in: PubMed
  86. Balsam LB, Wagers AJ, Christensen JL, Kofidis T, Weissman IL, Robbins RC. Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium. Nature. 2004 Apr 8; 428(6983):668-73.
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  87. Christensen JL, Wright DE, Wagers AJ, Weissman IL. Circulation and chemotaxis of fetal hematopoietic stem cells. PLoS Biol. 2004 Mar; 2(3):E75.
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  88. Wagers AJ, Weissman IL. Plasticity of adult stem cells. Cell. 2004 Mar 5; 116(5):639-48.
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  89. Sherwood RI, Christensen JL, Weissman IL, Wagers AJ. Determinants of skeletal muscle contributions from circulating cells, bone marrow cells, and hematopoietic stem cells. Stem Cells. 2004; 22(7):1292-304.
    View in: PubMed
  90. Yung Y, Cheshier S, Santarelli JG, Huang Z, Wagers AJ, Weissman IL, Tse V. Incorporation of naïve bone marrow derived cells into the vascular architecture of brain tumor. Microcirculation 2004. 2004; 11:699-708.
  91. Cao Y*, Wagers AJ*, Beilhack A, Dusich J, Bachmann MH, Negrin RS, Weissman IL, Contag CH *Equal contributors. Shifting Foci of Hematopoiesis during Reconstitution by Single Stem Cells. Proceedings of the National Academy of Science USA. 2004; 101:221-6.
  92. Christensen JL, Wright DE, Wagers AJ, Weissman IL. Constitutive circulation of HSC in fetal blood. PLoS Biology. 2004; 2:368-77.
  93. Cao YA, Wagers AJ, Beilhack A, Dusich J, Bachmann MH, Negrin RS, Weissman IL, Contag CH. Shifting foci of hematopoiesis during reconstitution from single stem cells. Proc Natl Acad Sci U S A. 2004 Jan 6; 101(1):221-6.
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  94. Kondo M, Wagers AJ, Manz MG, Prohaska SS, Scherer DC, Beilhack GF, Shizuru JA, Weissman IL. Biology of hematopoietic stem cells and progenitors: implications for clinical application. Annu Rev Immunol. 2003; 21:759-806.
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  95. Merad M, Manz MG, Karsunky H, Wagers A, Peters W, Charo I, Weissman IL, Cyster JG, Engleman EG. Langerhans cells renew in the skin throughout life under steady-state conditions. Nat Immunol. 2002 Dec; 3(12):1135-41.
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  96. Wagers AJ, Sherwood RI, Christensen JL, Weissman IL. Little evidence for developmental plasticity of adult hematopoietic stem cells. Science. 2002 Sep 27; 297(5590):2256-9.
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  97. Wright DE, Bowman EP, Wagers AJ, Butcher EC, Weissman IL. Hematopoietic stem cells are uniquely selective in their migratory response to chemokines. J Exp Med. 2002 May 6; 195(9):1145-54.
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  98. Wagers AJ, Christensen JL, Weissman IL. Cell fate determination from stem cells. Gene Ther. 2002 May; 9(10):606-12.
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  99. Wagers AJ, Allsopp RC, Weissman IL. Changes in integrin expression are associated with altered homing properties of Lin(-/lo)Thy1.1(lo)Sca-1(+)c-kit(+) hematopoietic stem cells following mobilization by cyclophosphamide/granulocyte colony-stimulating factor. Exp Hematol. 2002 Feb; 30(2):176-85.
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  100. Wright DE, Bowman EP, Wagers AJ, Butcher EC, Weissman IL. Highly enriched hematopoietic stem cells are uniquely selective in their migratory response to chemokines. Journal of Experimental Medicine. 2002; 195:1145-54.
  101. Wagers AJ, Allsopp RA, Weissman, IL. Changes in integrin expression are associated with altered homing properties of hematopoietic stem cells following mobilization by cyclophosphamide/ granulocyte colony-stimulating factor. Experimantal Hematology. 2002; (30):176-85.
  102. Wright DE, Wagers AJ, Gulati AP, Johnson FL, Weissman IL. Physiological migration of hematopoietic stem and progenitor cells. Science. 2001 Nov 30; 294(5548):1933-6.
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  103. Wright DE, Cheshier SH, Wagers AJ, Randall TD, Christensen JL, Weissman IL. Cyclophosphamide/granulocyte colony-stimulating factor causes selective mobilization of bone marrow hematopoietic stem cells into the blood after M phase of the cell cycle. Blood. 2001 Apr 15; 97(8):2278-85.
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  104. Wagers AJ, Kansas GS. Potent induction of alpha(1,3)-fucosyltransferase VII in activated CD4+ T cells by TGF-beta 1 through a p38 mitogen-activated protein kinase-dependent pathway. J Immunol. 2000 Nov 1; 165(9):5011-6.
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  105. Wagers AJ, Kansas GS. Potent induction of FucT-VII in activated CD4+ T cells by TGF-b1 through a p38 MAP kinase-dependent pathway. Journal of Immunology. 2000; 165:5011-6.
  106. Lim YC, Henault L, Wagers AJ, Kansas GS, Luscinskas FW, Lichtman AH. Expression of functional selectin ligands on Th cells is differentially regulated by IL-12 and IL-4. J Immunol. 1999 Mar 15; 162(6):3193-201.
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  107. Lim YC, Henault L, Wagers AJ, Kansas GS, Luscinskas FW, Lichtman AH. Expression of functional selectin ligands on helper T cells is differentially regulated by interleukin-12 and interleukin-4. Journal of Immunology. 1999; 162:3193-201.
  108. Wagers AJ. Regulation of alpha(1,3)-fucosyltransferase expression controls leukocyte adhesion to vascular selectins [dissertation]. 1999.
  109. Wagers AJ, Waters CM, Stoolman LM, Kansas GS. Interleukin 12 and interleukin 4 control T cell adhesion to endothelial selectins through opposite effects on alpha1, 3-fucosyltransferase VII gene expression. J Exp Med. 1998 Dec 21; 188(12):2225-31.
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  110. Wagers AJ, Stoolman LM, Craig R, Knibbs RN, Kansas GS. An sLex-deficient variant of HL60 cells exhibits high levels of adhesion to vascular selectins: further evidence that HECA-452 and CSLEX1 monoclonal antibody epitopes are not essential for high avidity binding to vascular selectins. J Immunol. 1998 May 15; 160(10):5122-9.
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  111. Wagers AJ, Waters CM, Stoolman LM, Kansas GS. IL-12 and IL-4 control T cell adhesion to endothelial selectins through opposite effects on FucT-VII gene expression. Journal of Experimental Medicine. 1998; 188:2225-31.
  112. Wagers AJ, Stoolman LM, Craig R, Knibbs RN, Kansas GS. An sLex-deficient variant of HL60 Cells exhibits high levels of adhesion to vascular selectins: further evidence that HECA-452 and CSLEX1 monoclonal antibody epitopes are not essential for high avidity binding to vascular selectins. Journal of Immunology. 1998; 160:3193-201.
  113. Wagers AJ, Stoolman LM, Kannagi R, Craig R, Kansas GS. Expression of leukocyte fucosyltransferases regulates binding to E-selectin: relationship to previously implicated carbohydrate epitopes. J Immunol. 1997 Aug 15; 159(4):1917-29.
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  114. Snapp KR, Wagers AJ, Craig R, Stoolman LM, Kansas GS. P-selectin glycoprotein ligand-1 is essential for adhesion to P-selectin but not E-selectin in stably transfected hematopoietic cell lines. Blood. 1997 Feb 1; 89(3):896-901.
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  115. Wagers AJ, Craig R, Kannagi R, Stoolman LM, Kansas GS. Expression of leukocyte fucosyltransferases regulates binding to E-selectin: relationship to previously implicated carbohydrate epitopes. Journal of Immunology. 1997; 159:1917-29.
  116. Wagers AJ, Lowe JB, Kansas GS. An important role for the alpha 1,3 fucosyltransferase, FucT-VII, in leukocyte adhesion to E-selectin. Blood. 1996 Sep 15; 88(6):2125-32.
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  117. BRECKENRIDGE RL, WAGERS AJ, BALTZELL WH. Lethal granuloma of the midline facial tissues; granuloma gangraenescens. Ann Otol Rhinol Laryngol. 1954 Jun; 63(2):278-95.
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