Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution

Lois A. Lampson, PH.D.

TitleAssociate Professor of Neurosurgery
InstitutionBrigham and Women's Hospital
DepartmentNeurosurgery
AddressBrigham & Women's Hospital
Neurosurgery, LMRC - 111
221 Longwood Ave
Boston MA 02115
Phone617/278-0363
Fax617/547-9580

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Lampson LA. Brain tumor immunotherapy: seeing the brain in the body. Drug Discov Today. 2013 Apr; 18(7-8):399-406.
    View in: PubMed
  2. Lampson LA. Monoclonal antibodies in neuro-oncology: Getting past the blood-brain barrier. MAbs. 2011 Mar-Apr; 3(2):153-60.
    View in: PubMed
  3. Lampson LA. Targeted therapy for neuro-oncology: reviewing the menu. Drug Discov Today. 2009 Feb; 14(3-4):185-91.
    View in: PubMed
  4. Dutta T, Spence A, Lampson LA. Robust ability of IFN-gamma to upregulate class II MHC antigen expression in tumor bearing rat brains. J Neurooncol. 2003 Aug-Sep; 64(1-2):31-44.
    View in: PubMed
  5. Lampson LA. Brain tumor immunotherapy: an immunologist's perspective. J Neurooncol. 2003 Aug-Sep; 64(1-2):3-11.
    View in: PubMed
  6. Lampson LA. New animal models to probe brain tumor biology, therapy, and immunotherapy: advantages and remaining concerns. J Neurooncol. 2001 Jul; 53(3):275-87.
    View in: PubMed
  7. McCluskey LP, Lampson LA. Local immune regulation in the central nervous system by substance P vs. glutamate. J Neuroimmunol. 2001 Jun 1; 116(2):136-46.
    View in: PubMed
  8. McCluskey LP, Lampson LA. Local neurochemicals and site-specific immune regulation in the CNS. J Neuropathol Exp Neurol. 2000 Mar; 59(3):177-87.
    View in: PubMed
  9. Phillips LM, Lampson LA. Site-specific control of T cell traffic in the brain: T cell entry to brainstem vs. hippocampus after local injection of IFN-gamma. J Neuroimmunol. 1999 May 3; 96(2):218-27.
    View in: PubMed
  10. Phillips LM, Simon PJ, Lampson LA. Site-specific immune regulation in the brain: differential modulation of major histocompatibility complex (MHC) proteins in brainstem vs. hippocampus. J Comp Neurol. 1999 Mar 15; 405(3):322-33.
    View in: PubMed
  11. Lampson LA. Beyond inflammation: site-directed immunotherapy. Immunol Today. 1998 Jan; 19(1):17-22.
    View in: PubMed
  12. Lampson LA. Interpreting MHC class I expression and class I/class II reciprocity in the CNS: reconciling divergent findings. Microsc Res Tech. 1995 Nov 1; 32(4):267-85.
    View in: PubMed
  13. Grabowska A, Lampson LA. MHC expression in nonlymphoid tissues of the developing embryo: strongest class I or class II expression in separate populations of potential antigen-presenting cells in the skin, lung, gut, and inter-organ connective tissue. Dev Comp Immunol. 1995 Sep-Oct; 19(5):425-50.
    View in: PubMed
  14. Lampson LA, Chen A, Vortmeyer AO, Sloan AE, Ghogawala Z, Kim L. Enhanced T cell migration to sites of microscopic CNS disease: complementary treatments evaluated by 2- and 3-D image analysis. Brain Pathol. 1994 Apr; 4(2):125-34.
    View in: PubMed
  15. Lehky TJ, Cowan EP, Lampson LA, Jacobson S. Induction of HLA class I and class II expression in human T-lymphotropic virus type I-infected neuroblastoma cells. J Virol. 1994 Mar; 68(3):1854-63.
    View in: PubMed
  16. Lampson LA, Grabowska A, Whelan JP. Class I and II MHC expression and its implications for regeneration in the nervous system. Prog Brain Res. 1994; 103:307-17.
    View in: PubMed
  17. Packard AB, Kronauge JF, Limpa-Amara N, Lampson L, O'Tuama LA, Jones AG. Tumor uptake of 99mTc-MIBI and 201Tl by a 9L gliosarcoma brain tumor model in rats. Nucl Med Biol. 1993 Aug; 20(6):773-6.
    View in: PubMed
  18. Drew PD, Lonergan M, Goldstein ME, Lampson LA, Ozato K, McFarlin DE. Regulation of MHC class I and beta 2-microglobulin gene expression in human neuronal cells. Factor binding to conserved cis-acting regulatory sequences correlates with expression of the genes. J Immunol. 1993 Apr 15; 150(8 Pt 1):3300-10.
    View in: PubMed
  19. Lampson LA, Lampson MA, Dunne AD. Exploiting the lacZ reporter gene for quantitative analysis of disseminated tumor growth within the brain: use of the lacZ gene product as a tumor antigen, for evaluation of antigenic modulation, and to facilitate image analysis of tumor growth in situ. Cancer Res. 1993 Jan 1; 53(1):176-82.
    View in: PubMed
  20. Lampson LA, Wen P, Roman VA, Morris JH, Sarid JA. Disseminating tumor cells and their interactions with leukocytes visualized in the brain. Cancer Res. 1992 Feb 15; 52(4):1018-25.
    View in: PubMed
  21. Wen PY, Lampson MA, Lampson LA. Effects of gamma-interferon on major histocompatibility complex antigen expression and lymphocytic infiltration in the 9L gliosarcoma brain tumor model: implications for strategies of immunotherapy. J Neuroimmunol. 1992 Jan; 36(1):57-68.
    View in: PubMed
  22. Sethna MP, Lampson LA. Immune modulation within the brain: recruitment of inflammatory cells and increased major histocompatibility antigen expression following intracerebral injection of interferon-gamma. J Neuroimmunol. 1991 Nov; 34(2-3):121-32.
    View in: PubMed
  23. Lampson LA, Kushner PD, Sobel RA. Major histocompatibility complex antigen expression in the affected tissues in amyotrophic lateral sclerosis. Ann Neurol. 1990 Sep; 28(3):365-72.
    View in: PubMed
  24. Kassis AI, Van den Abbeele AD, Wen PY, Baranowska-Kortylewicz J, Aaronson RA, DeSisto WC, Lampson LA, Black PM, Adelstein SJ. Specific uptake of the auger electron-emitting thymidine analogue 5-[123I/125I]iodo-2'-deoxyuridine in rat brain tumors: diagnostic and therapeutic implications in humans. Cancer Res. 1990 Aug 15; 50(16):5199-203.
    View in: PubMed
  25. Wen P, Loeffler JS, Morris JH, Lampson LA. The effects of irradiation on major histocompatibility complex expression and lymphocytic infiltration in the normal rat brain and the 9L gliosarcoma brain tumor model. J Neuroimmunol. 1990 May; 27(2-3):239-44.
    View in: PubMed
  26. Turner WJ, Chatten J, Lampson LA. Human neuroblastoma cell growth in xenogeneic hosts: comparison of T cell-deficient and NK-deficient hosts, and subcutaneous or intravenous injection routes. J Neurooncol. 1990 Apr; 8(2):121-32.
    View in: PubMed
  27. Lampson LA. MHC regulation in neural cells. Distribution of peripheral and internal beta 2-microglobulin and class I molecules in human neuroblastoma cell lines. J Immunol. 1990 Jan 15; 144(2):512-20.
    View in: PubMed
  28. Evans A, Main E, Zier K, Ikegaki N, Tartaglione M, Kennett R, Lampson L. The effects of gamma interferon on the natural killer and tumor cells of children with neuroblastoma. A preliminary report. Cancer. 1989 Oct 1; 64(7):1383-7.
    View in: PubMed
  29. Main EK, Monos DS, Lampson LA. IFN-treated neuroblastoma cell lines remain resistant to T cell-mediated allo-killing, and susceptible to non-MHC-restricted cytotoxicity. J Immunol. 1988 Nov 1; 141(9):2943-50.
    View in: PubMed
  30. Lampson LA, Siegel G. Defining the mechanisms that govern immune acceptance or rejection of neural tissue. Prog Brain Res. 1988; 78:243-7.
    View in: PubMed
  31. Lampson LA. Biological significance of HLA-A,B,C expression in neuroblastoma and related cell lines. Prog Clin Biol Res. 1988; 271:409-20.
    View in: PubMed
  32. Lampson LA, Whelan JP, Siegel G. Functional implications of class I MHC modulation in neural tissue. Ann N Y Acad Sci. 1988; 540:479-82.
    View in: PubMed
  33. Lavi E, Suzumura A, Lampson LA, Siegel RM, Murasko DM, Silberberg DH, Weiss SR. Expression of MHC class I genes in mouse hepatitis virus (MHV-A59) infection and in multiple sclerosis. Adv Exp Med Biol. 1987; 218:219-22.
    View in: PubMed
  34. Whelan JP, Eriksson U, Lampson LA. Expression of mouse beta 2-microglobulin in frozen and formaldehyde-fixed central nervous tissues: comparison of tissue behind the blood-brain barrier and tissue in a barrier-free region. J Immunol. 1986 Oct 15; 137(8):2561-6.
    View in: PubMed
  35. Whelan JP, Wysocki CJ, Lampson LA. Distribution of beta 2-microglobulin in olfactory epithelium: a proliferating neuroepithelium not protected by a blood-tissue barrier. J Immunol. 1986 Oct 15; 137(8):2567-71.
    View in: PubMed
  36. Lampson LA, Hickey WF. Monoclonal antibody analysis of MHC expression in human brain biopsies: tissue ranging from "histologically normal" to that showing different levels of glial tumor involvement. J Immunol. 1986 Jun 1; 136(11):4054-62.
    View in: PubMed
  37. Lampson LA, George DL. Interferon-mediated induction of class I MHC products in human neuronal cell lines: analysis of HLA and beta 2-m RNA, and HLA-A and HLA-B proteins and polymorphic specificities. J Interferon Res. 1986 Jun; 6(3):257-65.
    View in: PubMed
  38. Sterling P, Lampson LA. Molecular specificity of defined types of amacrine synapse in cat retina. J Neurosci. 1986 May; 6(5):1314-24.
    View in: PubMed
  39. Whelan JP, Chatten J, Lampson LA. HLA class I and beta 2-microglobulin expression in frozen and formaldehyde-fixed paraffin sections of neuroblastoma tumors. Cancer Res. 1985 Nov; 45(11 Pt 2):5976-83.
    View in: PubMed
  40. Main EK, Lampson LA, Hart MK, Kornbluth J, Wilson DB. Human neuroblastoma cell lines are susceptible to lysis by natural killer cells but not by cytotoxic T lymphocytes. J Immunol. 1985 Jul; 135(1):242-6.
    View in: PubMed
  41. Lampson LA, Fisher CA. Immunoblot specificity of monoclonal antibodies assayed against complex extracts. Anal Biochem. 1985 Jan; 144(1):55-64.
    View in: PubMed
  42. Lampson LA, Whelan JP, Fisher CA. HLA-A,B,C and beta 2-microglobulin are expressed weakly by human cells of neuronal origin, but can be induced in neuroblastoma cell lines by interferon. Prog Clin Biol Res. 1985; 175:379-88.
    View in: PubMed
  43. Lampson LA, Fisher CA. Weak HLA and beta 2-microglobulin expression of neuronal cell lines can be modulated by interferon. Proc Natl Acad Sci U S A. 1984 Oct; 81(20):6476-80.
    View in: PubMed
  44. Casadei JM, Gordon RD, Lampson LA, Schotland DL, Barchi RL. Monoclonal antibodies against the voltage-sensitive Na+ channel from mammalian skeletal muscle. Proc Natl Acad Sci U S A. 1984 Oct; 81(19):6227-31.
    View in: PubMed
  45. Lampson LA, Fisher CA, Whelan JP. Striking paucity of HLA-A, B, C and beta 2-microglobulin on human neuroblastoma cell lines. J Immunol. 1983 May; 130(5):2471-8.
    View in: PubMed
  46. Wachsberger P, Lampson L, Pepe FA. Non-uniform staining of myofibril a bands by a monoclonal antibody to skeletal muscle myosin S1 heavy chain. Tissue Cell. 1983; 15(3):341-9.
    View in: PubMed
  47. Lampson LA, Whelan JP. Paucity of HLA-A,B,C molecules on human cells of neuronal origin: microscopic analysis of neuroblastoma cell lines and tumor. Ann N Y Acad Sci. 1983; 420:107-14.
    View in: PubMed
  48. Shackelford DA, Lampson LA, Strominger JL. Separation of three class II antigens from a homozygous human B cell line. J Immunol. 1983 Jan; 130(1):289-96.
    View in: PubMed
  49. Shaw S, DeMars R, Schlossman SF, Smith PL, Lampson LA, Nadler LM. Serologic identification of the human secondary B cell antigens. Correlations between function, genetics, and structure. J Exp Med. 1982 Sep 1; 156(3):731-43.
    View in: PubMed
  50. Shackelford DA, Lampson LA, Strominger JL. Analysis of HLA-DR antigens by using monoclonal antibodies: recognition of conformational differences in biosynthetic intermediates. J Immunol. 1981 Oct; 127(4):1403-10.
    View in: PubMed
  51. Lampson LA, Levy R. Two populations of Ia-like molecules on a human B cell line. J Immunol. 1980 Jul; 125(1):293-9.
    View in: PubMed
  52. Lampson LA, Levy R. A role for clonal antigens in cancer diagnosis and therapy. J Natl Cancer Inst. 1979 Feb; 62(2):217-20.
    View in: PubMed
  53. Lampson LA, Levy R, Grumet FC, Ness D, Pious D. Production in vitro of murine antibody to a human histocompatibility alloantigen. Nature. 1978 Feb 2; 271(5644):461-2.
    View in: PubMed
  54. Levy R, Dilley J, Lampson LA. Human normal and leukemia cell surface antigens. Mouse monoclonal antibodies as probes. Curr Top Microbiol Immunol. 1978; 81:164-9.
    View in: PubMed
  55. Lampson LA, Royston I, Levy R. Homogeneous antibodies directed against human cell surface antigens: I. The mouse spleen fragment culture response to T and B cell lines derived from the same individual. J Supramol Struct. 1977; 6(3):441-8.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact Human Resources at faculty_serviceshms.harvard.edu.
Lampson's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
_
Co-Authors
_
Similar People
_
Same Department
Physical Neighbors
_