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Keywords
Last Name
Institution

Jeffrey MIchael Karp, Ph.D.

TitleAssociate Professor of Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressPartners Research Building
Renal Division
65 Landsdowne St
Cambridge MA 02139

 Overview 
 overview
Jeff Karp is an Assistant Professor at Harvard Medical School and is Co-Director of the Center for Regenerative Therapeutics at the Brigham and Women's Hospital. He is Principal Faculty at the Harvard Stem Cell Institute and is Affiliate Faculty at MIT through the HST program.
His research focuses on Stem Cell Engineering (towards elucidating basic mechanisms mediating the homing of Mesenchymal Stem Cells that drive innovative engineered solutions to control the fate and function of cells post-transplantation), Biomaterials (studying degradable prodrug-based self-assembled hydrogels as controlled drug-delivery systems), and Medical devices such as cell sorting chips that can be used to sort cells for diagnostic or therapeutic applications, needles that sense travel through tissues, or Gecko-inspired medical adhesives that was recently selected as one of Popular Mechanic's "Top 20 New Biotech Breakthroughs that Will Change Medicine”.
Dr. Karp has published more than 50 peer-reviewed papers, 15 book chapters, 60 abstracts, and has 25 issued or pending patents, a number of which have been licensed by biotech companies. Dr. Karp's work has been recognized by CNN, NPR Science Fridays, ABC News, MSNBC, CBC Quirks and Quarks, CanadaAM, BBC, Forbes, CBS Brink, Popular Science, the Washington Post, the New York Post, and by Wired Magazine.
In 2011 the Boston Business Journal recognized Dr. Karp as a Champion in Healthcare Innovation. MIT’s Technology Review Magazine (TR35) also recognized Dr. Karp as being one of the top innovators in the world under the age of 35. He received the 2010 Coulter Foundation Translational Young Investigator Award and the 2011 Society for Biomaterials Young Investigator Award. He currently serves as the Biology and Medicine Section Editor for the Journal Nanotechnology.
Dr. Karp is also an acclaimed mentor and innovator. He was selected as the Outstanding Faculty Undergraduate Mentor among all Faculty at MIT in 2008 and received the 2010 HST McMahon Mentoring award for being the top mentor among all faculty who mentor Harvard-MIT students. Jeff obtained a Ph.D. from the University of Toronto in 2004 at IBBME/Chem Eng where he worked with Professor John Davies and Molly Shoichet. Upon graduation, he was awarded the Paul B. Madsen Award for being the most innovative graduate student. He joined MIT as an NSERC Postdoctoral Fellow working in Institute Professor Robert Langer's laboratory from 2004-2007.


 Mentoring 
 current student opportunities
Available: 08/30/13, Expires: 08/29/15

We are always looking for highly innovative and self-driven individuals who have a passion for making a difference in the world through medical research. We have projects including development of nano-sensors, bioinspired adhesives, self-assembled drug delivery devices, devices to separate stem cells and circulating tumor cells, shape change and stimulus sensitive polymers, smart needles, intra-operative and bioengineered stem cell therapies, and development of next generation medical devices.

Available: 09/01/13, Expires: 09/05/16

We are always looking for highly innovative and self-driven individuals who have a passion for making a difference in the world through medical research. We have projects including development of nano-sensors, self-assembled drug delivery devices, devices to separate stem cells and circulating tumor cells, shape change and stimulus sensitive polymers, needles to sense various levels of tissue, intra-operative stem cell therapies, and general development of medical devices.


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Ankrum JA, Miranda OR, Ng KS, Sarkar D, Xu C, Karp JM. Engineering cells with intracellular agent-loaded microparticles to control cell phenotype. Nat Protoc. 2014 Feb; 9(2):233-45.
    View in: PubMed
  2. Lang N, Pereira MJ, Lee Y, Friehs I, Vasilyev NV, Feins EN, Ablasser K, O'Cearbhaill ED, Xu C, Fabozzo A, Padera R, Wasserman S, Freudenthal F, Ferreira LS, Langer R, Karp JM, Del Nido PJ. A blood-resistant surgical glue for minimally invasive repair of vessels and heart defects. Sci Transl Med. 2014 Jan 8; 6(218):218ra6.
    View in: PubMed
  3. Brindley DA, French A, Suh J, Roberts M, Davies B, Pinedo-Villanueva R, Wartolowska K, Rooke K, Kramm A, Judge A, Morrey M, Chandra A, Hurley H, Grover L, Bingham I, Siegel B, Rattley MS, Buckler RL, McKeon D, Krumholz K, Hook L, May M, Rikabi S, Pigott R, Morys M, Sabokbar A, Titus E, Laabi Y, Lemaitre G, Zahkia R, Sipp D, Horne R, Bravery C, Williams D, Wall I, Snyder EY, Karp JM, Barker RW, Bure K, Carr AJ, Reeve B. The implementation of novel collaborative structures for the identification and resolution of barriers to pluripotent stem cell translation. Stem Cells Dev. 2013 Dec; 22 Suppl 1:63-72.
    View in: PubMed
  4. Yin X, Farin HF, van Es JH, Clevers H, Langer R, Karp JM. Niche-independent high-purity cultures of Lgr5(+) intestinal stem cells and their progeny. Nat Methods. 2014 Jan; 11(1):106-12.
    View in: PubMed
  5. Choi S, Levy O, Coelho MB, Cabral JM, Karp JM, Karnik R. A cell rolling cytometer reveals the correlation between mesenchymal stem cell dynamic adhesion and differentiation state. Lab Chip. 2013 Nov 26; 14(1):161-6.
    View in: PubMed
  6. Mortensen LJ, Levy O, Phillips JP, Stratton T, Triana B, Ruiz JP, Gu F, Karp JM, Lin CP. Quantification of Mesenchymal Stem Cell (MSC) Delivery to a Target Site Using In Vivo Confocal Microscopy. PLoS One. 2013; 8(10):e78145.
    View in: PubMed
  7. Levy O, Anandakumaran P, Ngai J, Karnik R, Karp JM. Systematic Analysis of In Vitro Cell Rolling Using a Multi-well Plate Microfluidic System. J Vis Exp. 2013; (80).
    View in: PubMed
  8. Levy O, Zhao W, Mortensen LJ, Leblanc S, Tsang K, Fu M, Phillips JA, Sagar V, Anandakumaran P, Ngai J, Cui CH, Eimon P, Angel M, Lin CP, Yanik MF, Karp JM. mRNA-engineered mesenchymal stem cells for targeted delivery of interleukin-10 to sites of inflammation. Blood. 2013 Oct 3; 122(14):e23-32.
    View in: PubMed
  9. Bose S, Singh R, Hanewich-Hollatz M, Shen C, Lee CH, Dorfman DM, Karp JM, Karnik R. Affinity flow fractionation of cells via transient interactions with asymmetric molecular patterns. Sci Rep. 2013 Jul 31; 3:2329.
    View in: PubMed
  10. Yang SY, O'Cearbhaill ED, Sisk GC, Park KM, Cho WK, Villiger M, Bouma BE, Pomahac B, Karp JM. A bio-inspired swellable microneedle adhesive for mechanical interlocking with tissue. Nat Commun. 2013 Apr 16; 4:1702.
    View in: PubMed
  11. Vemula PK, Wiradharma N, Ankrum JA, Miranda OR, John G, Karp JM. Prodrugs as self-assembled hydrogels: a new paradigm for biomaterials. Curr Opin Biotechnol. 2013 Dec; 24(6):1174-82.
    View in: PubMed
  12. Pereira MJ, Ouyang B, Sundback CA, Lang N, Friehs I, Mureli S, Pomerantseva I, McFadden J, Mochel MC, Mwizerwa O, Del Nido P, Sarkar D, Masiakos PT, Langer R, Ferreira LS, Karp JM. A highly tunable biocompatible and multifunctional biodegradable elastomer. Adv Mater. 2013 Feb 25; 25(8):1209-15.
    View in: PubMed
  13. Cho WK, Ankrum JA, Guo D, Chester SA, Yang SY, Kashyap A, Campbell GA, Wood RJ, Rijal RK, Karnik R, Langer R, Karp JM. Microstructured barbs on the North American porcupine quill enable easy tissue penetration and difficult removal. Proc Natl Acad Sci U S A. 2012 Dec 26; 109(52):21289-94.
    View in: PubMed
  14. Zhao W, Cui CH, Bose S, Guo D, Shen C, Wong WP, Halvorsen K, Farokhzad OC, Teo GS, Phillips JA, Dorfman DM, Karnik R, Karp JM. Bioinspired multivalent DNA network for capture and release of cells. Proc Natl Acad Sci U S A. 2012 Nov 27; 109(48):19626-31.
    View in: PubMed
  15. Teo GS, Ankrum JA, Martinelli R, Boetto SE, Simms K, Sciuto TE, Dvorak AM, Karp JM, Carman CV. Mesenchymal Stem Cells Transmigrate Between and Directly Through Tumor Necrosis Factor-a-Activated Endothelial Cells Via Both Leukocyte-Like and Novel Mechanisms. Stem Cells. 2012 Nov; 30(11):2472-86.
    View in: PubMed
  16. Laulicht B, Langer R, Karp JM. Quick-release medical tape. Proc Natl Acad Sci U S A. 2012 Nov 13; 109(46):18803-8.
    View in: PubMed
  17. Xu C, Poh YK, Roes I, O'Cearbhaill ED, Matthiesen ME, Mu L, Yang SY, Miranda-Nieves D, Irimia D, Karp JM. A portable chemotaxis platform for short and long term analysis. PLoS One. 2012; 7(9):e44995.
    View in: PubMed
  18. Xu C, Miranda-Nieves D, Ankrum JA, Matthiesen ME, Phillips JA, Roes I, Wojtkiewicz GR, Juneja V, Kultima JR, Zhao W, Vemula PK, Lin CP, Nahrendorf M, Karp JM. Tracking mesenchymal stem cells with iron oxide nanoparticle loaded poly(lactide-co-glycolide) microparticles. Nano Lett. 2012 Aug 8; 12(8):4131-9.
    View in: PubMed
  19. Ali MM, Kang DK, Tsang K, Fu M, Karp JM, Zhao W. Cell-surface sensors: lighting the cellular environment. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2012 Sep-Oct; 4(5):547-61.
    View in: PubMed
  20. Ranganath SH, Levy O, Inamdar MS, Karp JM. Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease. Cell Stem Cell. 2012 Mar 2; 10(3):244-58.
    View in: PubMed
  21. Choi S, Karp JM, Karnik R. Cell sorting by deterministic cell rolling. Lab Chip. 2012 Apr 21; 12(8):1427-30.
    View in: PubMed
  22. Coelho MB, Cabral JM, Karp JM. Intraoperative stem cell therapy. Annu Rev Biomed Eng. 2012; 14:325-49.
    View in: PubMed
  23. Gill JB, Karp JM, Kopycka-Kedzierawski DT. Oral piercing injuries treated in United States emergency departments, 2002-2008. Pediatr Dent. 2012 Jan-Feb; 34(1):56-60.
    View in: PubMed
  24. Zhao W, Karp JM, Ferrari M, Serda R. Bioengineering nanotechnology: towards the clinic. Nanotechnology. 2011 Dec 9; 22(49):490201.
    View in: PubMed
  25. Xu C, Mu L, Roes I, Miranda-Nieves D, Nahrendorf M, Ankrum JA, Zhao W, Karp JM. Nanoparticle-based monitoring of cell therapy. Nanotechnology. 2011 Dec 9; 22(49):494001.
    View in: PubMed
  26. Sarkar D, Spencer JA, Phillips JA, Zhao W, Schafer S, Spelke DP, Mortensen LJ, Ruiz JP, Vemula PK, Sridharan R, Kumar S, Karnik R, Lin CP, Karp JM. Engineered cell homing. Blood. 2011 Dec 15; 118(25):e184-91.
    View in: PubMed
  27. Karp JM, Langer R. Materials science: Dry solution to a sticky problem. Nature. 2011 Sep 1; 477(7362):42-3.
    View in: PubMed
  28. Zhao W, Schafer S, Choi J, Yamanaka YJ, Lombardi ML, Bose S, Carlson AL, Phillips JA, Teo W, Droujinine IA, Cui CH, Jain RK, Lammerding J, Love JC, Lin CP, Sarkar D, Karnik R, Karp JM. Cell-surface sensors for real-time probing of cellular environments. Nat Nanotechnol. 2011 Aug; 6(8):524-31.
    View in: PubMed
  29. Pereira MJ, Carvalho IF, Karp JM, Ferreira LS. Sensing the cardiac environment: exploiting cues for regeneration. J Cardiovasc Transl Res. 2011 Oct; 4(5):616-30.
    View in: PubMed
  30. Zhao W, Loh W, Droujinine IA, Teo W, Kumar N, Schafer S, Cui CH, Zhang L, Sarkar D, Karnik R, Karp JM. Mimicking the inflammatory cell adhesion cascade by nucleic acid aptamer programmed cell-cell interactions. FASEB J. 2011 Sep; 25(9):3045-56.
    View in: PubMed
  31. Vemula PK, Anderson RR, Karp JM. Nanoparticles reduce nickel allergy by capturing metal ions. Nat Nanotechnol. 2011 May; 6(5):291-5.
    View in: PubMed
  32. Vemula PK, Boilard E, Syed A, Campbell NR, Muluneh M, Weitz DA, Lee DM, Karp JM. On-demand drug delivery from self-assembled nanofibrous gels: a new approach for treatment of proteolytic disease. J Biomed Mater Res A. 2011 May; 97(2):103-10.
    View in: PubMed
  33. Lee CH, Bose S, Van Vliet KJ, Karp JM, Karnik R. Studying cell rolling trajectories on asymmetric receptor patterns. J Vis Exp. 2011; (48).
    View in: PubMed
  34. Sarkar D, Ankrum JA, Teo GS, Carman CV, Karp JM. Cellular and extracellular programming of cell fate through engineered intracrine-, paracrine-, and endocrine-like mechanisms. Biomaterials. 2011 Apr; 32(11):3053-61.
    View in: PubMed
  35. Sarkar D, Zhao W, Gupta A, Loh WL, Karnik R, Karp JM. Cell surface engineering of mesenchymal stem cells. Methods Mol Biol. 2011; 698:505-23.
    View in: PubMed
  36. Mitsouras D, Vemula PK, Yu P, Tao M, Nguyen BT, Campagna CM, Karp JM, Mulkern RV, Ozaki CK, Rybicki FJ. Immobilized contrast-enhanced MRI: Gadolinium-based long-term MR contrast enhancement of the vein graft vessel wall. Magn Reson Med. 2011 Jan; 65(1):176-83.
    View in: PubMed
  37. Chan EP, Karp JM, Langer RS. A "Self-Pinning" Adhesive Based on Responsive Surface Wrinkles. J Polym Sci B Polym Phys. 2011 Jan 1; 49(1):40-44.
    View in: PubMed
  38. Spelke DP, Ortmann D, Khademhosseini A, Ferreira L, Karp JM. Methods for embryoid body formation: the microwell approach. Methods Mol Biol. 2011; 690:151-62.
    View in: PubMed
  39. Karp JM. Delayed tooth emergence. Pediatr Rev. 2011 Jan; 32(1):e4-17.
    View in: PubMed
  40. Bose S, Das SK, Karp JM, Karnik R. A semianalytical model to study the effect of cortical tension on cell rolling. Biophys J. 2010 Dec 15; 99(12):3870-9.
    View in: PubMed
  41. Lee CH, Bose S, Van Vliet KJ, Karp JM, Karnik R. Examining the lateral displacement of HL60 cells rolling on asymmetric P-selectin patterns. Langmuir. 2011 Jan 4; 27(1):240-9.
    View in: PubMed
  42. Kang SM, You I, Cho WK, Shon HK, Lee TG, Choi IS, Karp JM, Lee H. One-step modification of superhydrophobic surfaces by a mussel-inspired polymer coating. Angew Chem Int Ed Engl. 2010 Dec 3; 49(49):9401-4.
    View in: PubMed
  43. Nguyen BT, Vemula PK, Mitsouras D, Yu P, Tao M, Campagna C, Mulkern RV, Rybicki FJ, Karp JM, Ozaki CK. Immobilization of iron oxide magnetic nanoparticles for enhancement of vessel wall magnetic resonance imaging--an ex vivo feasibility study. Bioconjug Chem. 2010 Aug 18; 21(8):1408-12.
    View in: PubMed
  44. Sarkar D, Vemula PK, Zhao W, Gupta A, Karnik R, Karp JM. Engineered mesenchymal stem cells with self-assembled vesicles for systemic cell targeting. Biomaterials. 2010 Jul; 31(19):5266-74.
    View in: PubMed
  45. Zhao W, Teo GS, Kumar N, Karp JM. Chemistry and material science at the cell surface. Mater Today (Kidlington). 2010 Apr; 13(4):14-21.
    View in: PubMed
  46. Ankrum J, Karp JM. Mesenchymal stem cell therapy: Two steps forward, one step back. Trends Mol Med. 2010 May; 16(5):203-9.
    View in: PubMed
  47. Zhao W, Karp JM. Controlling cell fate in vivo. Chembiochem. 2009 Sep 21; 10(14):2308-10.
    View in: PubMed
  48. Zhao W, Karp JM. Tumour targeting: Nanoantennas heat up. Nat Mater. 2009 Jun; 8(6):453-4.
    View in: PubMed
  49. Bassett EK, Slocum AH, Masiakos PT, Pryor HI, Farokhzad OC, Karp JM. Design of a mechanical clutch-based needle-insertion device. Proc Natl Acad Sci U S A. 2009 Apr 7; 106(14):5540-5.
    View in: PubMed
  50. Karp JM, Leng Teo GS. Mesenchymal stem cell homing: the devil is in the details. Cell Stem Cell. 2009 Mar 6; 4(3):206-16.
    View in: PubMed
  51. Sarkar D, Vemula PK, Teo GS, Spelke D, Karnik R, Wee le Y, Karp JM. Chemical engineering of mesenchymal stem cells to induce a cell rolling response. Bioconjug Chem. 2008 Nov 19; 19(11):2105-9.
    View in: PubMed
  52. Vemula PK, Cruikshank GA, Karp JM, John G. Self-assembled prodrugs: an enzymatically triggered drug-delivery platform. Biomaterials. 2009 Jan; 30(3):383-93.
    View in: PubMed
  53. Ferreira L, Karp JM, Nobre L, Langer R. New opportunities: the use of nanotechnologies to manipulate and track stem cells. Cell Stem Cell. 2008 Aug 7; 3(2):136-46.
    View in: PubMed
  54. Wright D, Rajalingam B, Karp JM, Selvarasah S, Ling Y, Yeh J, Langer R, Dokmeci MR, Khademhosseini A. Reusable, reversibly sealable parylene membranes for cell and protein patterning. J Biomed Mater Res A. 2008 May; 85(2):530-8.
    View in: PubMed
  55. Karnik R, Hong S, Zhang H, Mei Y, Anderson DG, Karp JM, Langer R. Nanomechanical control of cell rolling in two dimensions through surface patterning of receptors. Nano Lett. 2008 Apr; 8(4):1153-8.
    View in: PubMed
  56. Mahdavi A, Ferreira L, Sundback C, Nichol JW, Chan EP, Carter DJ, Bettinger CJ, Patanavanich S, Chignozha L, Ben-Joseph E, Galakatos A, Pryor H, Pomerantseva I, Masiakos PT, Faquin W, Zumbuehl A, Hong S, Borenstein J, Vacanti J, Langer R, Karp JM. A biodegradable and biocompatible gecko-inspired tissue adhesive. Proc Natl Acad Sci U S A. 2008 Feb 19; 105(7):2307-12.
    View in: PubMed
  57. Luo y, Engelmayr G, Karp JM, Ferreira L, Auguste ET, Saigal R, Langer R. Scaffolds for Tissue Engineering. Principles of Tissue Engineering. 2008; 1:359-368.
  58. Ma H, Karp JM. Microfluidic Cell Filtering Device. 2008.
  59. Farokhzad O, Slocum A, Karp JM, Basset E, Langer R. A device for sensing tissues. 2008.
  60. Chan EP, Karp JM, Langer R. Stimuli responsive surfaces. 2008.
  61. Karp JM, Sarkar D, KV Praveen. Engineering cell function. 2008.
  62. Karp JM, Sarkar D, Graneli C. Methods and compositions relating to connective tissue progenitor cells. 2008.
  63. Yang, Neeley WL, Moore MJ, Karp JM, Shukla A, Langer R. Tissue Engineering: The Therapeutic Strategy of the 21st Century. Nanotechnology and Tissue Engineering: The Scaffold. 2008; 3-32.
  64. Karp JM, Mahdavi A, Hong S, Khademhosseini A, Langer R. Microscale apporaches for bone tissue engineering. Mico and Nanoengineering of the Cellular Microenvironment: Applications and Technologies. 2008; 1:417-430.
  65. Kumar Vemula P, John G, Karp JM. Methods and Compositions Relating to Self-Assembling Amphiphiles as Drug Delivery Devices. 2008.
  66. Peer D, Karp JM, Hong S, Farokhzad OC, Margalit R, Langer R. Nanocarriers as an emerging platform for cancer therapy. Nat Nanotechnol. 2007 Dec; 2(12):751-60.
    View in: PubMed
  67. Karp JM, Langer R. Development and therapeutic applications of advanced biomaterials. Curr Opin Biotechnol. 2007 Oct; 18(5):454-9.
    View in: PubMed
  68. Hong S, Lee D, Zhang H, Zhang JQ, Resvick JN, Khademhosseini A, King MR, Langer R, Karp JM. Covalent immobilization of p-selectin enhances cell rolling. Langmuir. 2007 Nov 20; 23(24):12261-8.
    View in: PubMed
  69. Nijst CL, Bruggeman JP, Karp JM, Ferreira L, Zumbuehl A, Bettinger CJ, Langer R. Synthesis and characterization of photocurable elastomers from poly(glycerol-co-sebacate). Biomacromolecules. 2007 Oct; 8(10):3067-73.
    View in: PubMed
  70. Kim GY, Tyler BM, Tupper MM, Karp JM, Langer RS, Brem H, Cima MJ. Resorbable polymer microchips releasing BCNU inhibit tumor growth in the rat 9L flank model. J Control Release. 2007 Nov 6; 123(2):172-8.
    View in: PubMed
  71. Ling Y, Rubin J, Deng Y, Huang C, Demirci U, Karp JM, Khademhosseini A. A cell-laden microfluidic hydrogel. Lab Chip. 2007 Jun; 7(6):756-62.
    View in: PubMed
  72. Karp JM, Yeh J, Eng G, Fukuda J, Blumling J, Suh KY, Cheng J, Mahdavi A, Borenstein J, Langer R, Khademhosseini A. Controlling size, shape and homogeneity of embryoid bodies using poly(ethylene glycol) microwells. Lab Chip. 2007 Jun; 7(6):786-94.
    View in: PubMed
  73. Gerecht S, Townsend S, Pressler H, Karp JM, Langer R. Bioelastomer material for the encapsulation of cells. 2007.
  74. Karp JM, Gu F, Khademhosseini A, Berry DA, Langer R. Methods and compositions to alter biological surfaces. 2007.
  75. Karp JM, Nijst C, Zumbuehl A, Ferreira, Bruggeman J, Bettinger C, Burdick JA, Langer R. Robust biodegradable elastomers. 2007.
  76. Nijst C, Bruggemann J, Karp JM, Zumbheul A, Ferreira L, Bettinger C, Langer R. “Development of multifunctional photocurable degradable elastomers. Tissue Engineering and Regenerative Medicine International Conference. 2007.
  77. Karp JM, Hong S, Khademhosseini, A, Moore M, Langer R. Materials for influencing cell motility. 2007.
  78. Karnik RN, Hong S, Karp JM, Mei Y, Anderson DG, Langer RS. Methods for Cell Separation and Cytometry Based on Directed Cell Rolling on Patterned Substrates. 2007.
  79. Karp JM, Mahdavi A, Ferreira L, Carter D, Zumbuehl A, Borenstein J, Bettinger C, Langer R. Gecko Mimicking Adhesives. 2007.
  80. Karp JM, Langer R. Injectable Stem Cell Formulation. 2007.
  81. Karp JM, Peer D*, Hong S, Farokhzad O, Margalit R, Langer R. Nanocarriers: Emerging Platforms for Cancer Therapy. Nature Nanotechnology. 2007; 2:751-760.
  82. Rivest C, Morrison D, Rubin J, Ni B, Mahdavi A, Karp JM, Khademhosseini A. Microscale hydrogels: fabrication, applications and mechnical properties. Journal of Mechanics of Materials and Structures. 2007; 2(6):1103-19.
  83. Karp JM, Gu F, Khademhosseini A, Berry DA, Langer R. Methods for targeting osteoporosis. 2007.
  84. Karp JM, Ferreira LS, Khademhosseini A, Langer R. In vitro Differentiation of Human ES Cells Along Osteogenic Pathways. Human Embryonic Stem Cells - A Practical Handbook. 2007; 1:249-271.
  85. Karp JM, Ganoza GG. Dental trauma after cardiac syncope in a patient with long QT syndrome. Pediatr Dent. 2006 Nov-Dec; 28(6):547-52.
    View in: PubMed
  86. Farokhzad OC, Dimitrakov JD, Karp JM, Khademhosseini A, Freeman MR, Langer R. Drug delivery systems in urology--getting "smarter". Urology. 2006 Sep; 68(3):463-9.
    View in: PubMed
  87. Khademhosseini A, Ferreira L, Blumling J, Yeh J, Karp JM, Fukuda J, Langer R. Co-culture of human embryonic stem cells with murine embryonic fibroblasts on microwell-patterned substrates. Biomaterials. 2006 Dec; 27(36):5968-77.
    View in: PubMed
  88. Yeh J, Ling Y, Karp JM, Gantz J, Chandawarkar A, Eng G, Blumling J, Langer R, Khademhosseini A. Micromolding of shape-controlled, harvestable cell-laden hydrogels. Biomaterials. 2006 Nov; 27(31):5391-8.
    View in: PubMed
  89. Kark LR, Karp JM, Davies JE. Platelet releasate increases the proliferation and migration of bone marrow-derived cells cultured under osteogenic conditions. Clin Oral Implants Res. 2006 Jun; 17(3):321-7.
    View in: PubMed
  90. Karp JM, Yeo Y, Geng W, Cannizarro C, Yan K, Kohane DS, Vunjak-Novakovic G, Langer RS, Radisic M. A photolithographic method to create cellular micropatterns. Biomaterials. 2006 Sep; 27(27):4755-64.
    View in: PubMed
  91. Karp J, Bryk J, Menke E, McTigue D. The complete endodontic obturation of an avulsed immature permanent incisor with mineral trioxide aggregate: a case report. Pediatr Dent. 2006 May-Jun; 28(3):273-8.
    View in: PubMed
  92. Karp JM, Moss AJ. Dental treatment of patients with long QT syndrome. J Am Dent Assoc. 2006 May; 137(5):630-7.
    View in: PubMed
  93. Farokhzad OC, Karp JM, Langer R. Nanoparticle-aptamer bioconjugates for cancer targeting. Expert Opin Drug Deliv. 2006 May; 3(3):311-24.
    View in: PubMed
  94. Karp JM, Bettinger C, Zumbuehl A, Ferreira L, Langer R. A method for low temperature crosslinking of biodegradable polymers. 2006.
  95. Karp JM, Ferreria L, Yeo Y, Khademhosseini A, Langer R. Development of highly regenerative desiccants. 2006.
  96. Karp JM, Farokhzad O, Dimitrakov J, Langer R. Drug delivery systems in urology – getting “smarter". Urology. 2006; 68(3):463-9.
  97. Karp JM, Khademhosseini A, Ferreira L, Blumling J, Yeh J, Fukuda J, Eng K, Gantz J, Langer R. Micropatterned co-cultures of human embryonic stem cells with murine embryonic fibroblasts. Canadian Society for Biomaterials. 2006.
  98. Khademhosseini A, Ling Y, Karp JM, Langer R. Micro and Nanoscale Control of Cellular Environment for Tissue Engineering. Innovations in Nanotechnology. 2006.
  99. Khademhosseini A, Ling y, Karp JM, Langer R. Micro- and nanoscale control of cellular environment for tissue engineering. Nanobiotechnology: Concepts, Applications and Perspectives. 2006; 349-366.
  100. Khademhosseini A, Moore M, Karp JM, Langer R. A platform technology based on bioactive hydrogels. 2006.
  101. Ling Y, Rubin J, Karp JM, Khademhosseini A. Agarose Microfluidics Devices for Diagnostics and Tissue Engineering. 2006 Materials Research Society Fall Meeting. 2006.
  102. Khademhosseini A, Eng G, Yeh J, Fukuda J, Blumling J, Karp JM, Langer R, Burdick JA. Micromolding of photocrosslinkable hyaluronic acid for cell encapsulation and entrapment. Society for Biomaterials Meeting. 2006.
  103. Farokhzad O., Karp JM, Langer R. Nanoparticle-Aptamer Conjugates for targeted Cancer Therapy. Expert Opinion Drug Delivery. 2006; 3(3):311-324.
  104. Karp JM, Khademhosseini A, Gerecht-Ni S, Perreira L, Vunjak-Novakovic G, Langer R. Embryonic Stem Cells For a Source For Tissue Engineering. Principles of Tissue Engineering. 2006.
  105. Ling, Y, Yeh J, Karp JM, Chandawarkar A, Gantz J, Langer R, Khademhosseini . Shape and size-controlled photocrosslinkable microgels for encapsulation of embryonic stem cells. 2006 International Society of Stem cell Research Meeting. 2006.
  106. Khademhosseini A, Farokhzad, O, Karp JM, Langer R. Microencapsulation of cells within shape-controlled biomaterials as building blocks for engineering tissues and organs. 2006.
  107. Nijst C, Karp JM, Bruggemann J, Zumbheul A, Ferreira L, Bettinger C, Langer R. Development of multifunctional photocurable degradable elastomers. 2006 Materials Research Society Fall Meeting. 2006.
  108. Khademhosseini A, Bettinger C, Karp JM, Yeh J, Ling Y, Borenstein J, Fukuda J, Langer R. Interplay of biomaterials and microscale technologies: building on each other to advance biomedical applications. Journal of Biomaterials Science - Polymer Edition. 2006; 17(11):1221-40.
  109. Khademhosseini A, Bettinger C, Karp JM, Yeh J, Ling Y, Borenstein J, Fukuda J, Langer R. Interplay of biomaterials and micro-scale technologies for advancing biomedical applications. J Biomater Sci Polym Ed. 2006; 17(11):1221-40.
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  110. Karp JM, Ferreira LS, Khademhosseini A, Kwon AH, Yeh J, Langer RS. Cultivation of human embryonic stem cells without the embryoid body step enhances osteogenesis in vitro. Stem Cells. 2006 Apr; 24(4):835-43.
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  111. Khademhosseini A, Yeh J, Eng G, Karp J, Kaji H, Borenstein J, Farokhzad OC, Langer R. Cell docking inside microwells within reversibly sealed microfluidic channels for fabricating multiphenotype cell arrays. Lab Chip. 2005 Dec; 5(12):1380-6.
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  112. Karp JM, Tanaka TS, Zohar R, Sodek J, Shoichet MS, Davies JE, Stanford WL. Thrombin mediated migration of osteogenic cells. Bone. 2005 Sep; 37(3):337-48.
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  113. Kim G, Tyler B, Karp JM, Brem H, Cima MJ, Langer R. Polymer microchip for drug delivery. 8th US-JAPAN symposium on Drug Delivery Systems. 2005.
  114. Karp JM, Ferreira L, Khademhosseini A, Langer R. Amplification of cell populations from embryonic stem cells. 2005.
  115. Khademhosseini A, Eng G, Yeh J, Fukuda J, Karp JM, Langer R. Homogenous spheroid arrays and patterned spheriod co-cultures on micropatterened surfaces. 2005.
  116. Yeh J, Khademhosseini A, Ferreira L, Karp JM, Fukuda J, Eng G, Blumbling J, Morin-Leisk J, Gantz J, Langer R, Burdick J. Microstructure mediated patterned co-cultures. 2005 Materials Research Society Fall Meeting. 2005.
  117. Karp JM, Sarraf F, Shoichet MS, Davies JE. Fibrin-filled scaffolds for bone-tissue engineering: An in vivo study. J Biomed Mater Res A. 2004 Oct 1; 71(1):162-71.
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  118. Karp JM, Friis EA, Dee KC, Winet H. Opinions and trends in biomaterials education: report of a 2003 Society for Biomaterials survey. J Biomed Mater Res A. 2004 Jul 1; 70(1):1-9.
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  119. Karp JM. Effects of Thrombin on the Migration of Primary Osteogenic Cells through fibrin-filled scaffolds [Ph.D. dissertation]. 2004.
  120. Oprea WE, Karp JM, Hosseini MM, Davies JE. Effect of platelet releasate on bone cell migration and recruitment in vitro. J Craniofac Surg. 2003 May; 14(3):292-300.
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  121. Karp JM, Rzeszutek K, Shoichet MS, Davies JE. Fabrication of precise cylindrical three-dimensional tissue engineering scaffolds for in vitro and in vivo bone engineering applications. J Craniofac Surg. 2003 May; 14(3):317-23.
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  122. Karp JM, Shoichet MS, Davies JE. Bone formation on two-dimensional poly(DL-lactide-co-glycolide) (PLGA) films and three-dimensional PLGA tissue engineering scaffolds in vitro. J Biomed Mater Res A. 2003 Feb 1; 64(2):388-96.
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  123. Karp JM, Dalton PD, Shoichet, MS. Scaffolds for tissue engineering. MRS Bulletin on cellular solids. 2003; 28(4):301-306.
  124. Jeffrey M. Karp. Biomaterials Surgical Video Library. 2002.
  125. Davies JE, Karp JM, Baksh D. Mesenchymal cell culture: bone. Methods of Tissue Engineering. 2001; 333-334.
  126. Shah MS, Ullman JC, Karp J. Pelvic kidney secondary to false-positive renal scan. Error in diagnosis. Urology. 1974 Aug; 4(2):212-3.
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