Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution

Nathan Judson McDannold, PH.D.

TitleAssociate Professor of Radiology
InstitutionBrigham and Women's Hospital
DepartmentRadiology
AddressBrigham and Women's Hospital
Radiology
75 Francis St
Boston MA 02115
Phone617/278-0605
Fax617/525-7450

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Jolesz FA, McDannold NJ. Magnetic resonance-guided focused ultrasound: a new technology for clinical neurosciences. Neurol Clin. 2014 Feb; 32(1):253-69.
    View in: PubMed
  2. Arvanitis CD, McDannold N. Integrated ultrasound and magnetic resonance imaging for simultaneous temperature and cavitation monitoring during focused ultrasound therapies. Med Phys. 2013 Nov; 40(11):112901.
    View in: PubMed
  3. McDannold N. Targeted drug delivery to the brain and brain tumors using focused ultrasound and microbubbles. J Acoust Soc Am. 2013 Nov; 134(5):4089.
    View in: PubMed
  4. McDannold N, Zhang YZ, Power C, Jolesz F, Vykhodtseva N. Nonthermal ablation with microbubble-enhanced focused ultrasound close to the optic tract without affecting nerve function. J Neurosurg. 2013 Nov; 119(5):1208-20.
    View in: PubMed
  5. Arvanitis CD, Livingstone MS, McDannold N. Combined ultrasound and MR imaging to guide focused ultrasound therapies in the brain. Phys Med Biol. 2013 Jul 21; 58(14):4749-61.
    View in: PubMed
  6. Aryal M, Vykhodtseva N, Zhang YZ, Park J, McDannold N. Multiple treatments with liposomal doxorubicin and ultrasound-induced disruption of blood-tumor and blood-brain barriers improve outcomes in a rat glioma model. J Control Release. 2013 Jul 10; 169(1-2):103-11.
    View in: PubMed
  7. Kopechek JA, Park E, Mei CS, McDannold NJ, Porter TM. Accumulation of Phase-Shift Nanoemulsions to Enhance MR-Guided Ultrasound-Mediated Tumor Ablation In Vivo. J Healthc Eng. 2013 Mar 1; 4(1):109-26.
    View in: PubMed
  8. Arvanitis CD, Livingstone MS, Vykhodtseva N, McDannold N. Controlled ultrasound-induced blood-brain barrier disruption using passive acoustic emissions monitoring. PLoS One. 2012; 7(9):e45783.
    View in: PubMed
  9. Park EJ, Zhang YZ, Vykhodtseva N, McDannold N. Ultrasound-mediated blood-brain/blood-tumor barrier disruption improves outcomes with trastuzumab in a breast cancer brain metastasis model. J Control Release. 2012 Nov 10; 163(3):277-84.
    View in: PubMed
  10. Park J, Zhang Y, Vykhodtseva N, Akula JD, McDannold NJ. Targeted and reversible blood-retinal barrier disruption via focused ultrasound and microbubbles. PLoS One. 2012; 7(8):e42754.
    View in: PubMed
  11. Treat LH, McDannold N, Zhang Y, Vykhodtseva N, Hynynen K. Improved anti-tumor effect of liposomal doxorubicin after targeted blood-brain barrier disruption by MRI-guided focused ultrasound in rat glioma. Ultrasound Med Biol. 2012 Oct; 38(10):1716-25.
    View in: PubMed
  12. Park J, Zhang Y, Vykhodtseva N, Jolesz FA, McDannold NJ. The kinetics of blood brain barrier permeability and targeted doxorubicin delivery into brain induced by focused ultrasound. J Control Release. 2012 Aug 20; 162(1):134-42.
    View in: PubMed
  13. Schwartz BM, McDannold NJ. Ultrasound echoes as biometric navigators. Magn Reson Med. 2013 Apr; 69(4):1023-33.
    View in: PubMed
  14. McDannold N, Arvanitis CD, Vykhodtseva N, Livingstone MS. Temporary disruption of the blood-brain barrier by use of ultrasound and microbubbles: safety and efficacy evaluation in rhesus macaques. Cancer Res. 2012 Jul 15; 72(14):3652-63.
    View in: PubMed
  15. Aljallad MH, Yuan J, Pilatou MC, McDannold NJ, Panych LP. Multiresolution MRI temperature monitoring in a reduced field of view. Magn Reson Imaging. 2011 Nov; 29(9):1205-14.
    View in: PubMed
  16. Mei CS, Mulkern RV, Oshio K, Chen NK, Madore B, Panych LP, Hynynen K, McDannold NJ. Ultrafast 1D MR thermometry using phase or frequency mapping. MAGMA. 2012 Feb; 25(1):5-14.
    View in: PubMed
  17. McDannold N, Zhang Y, Vykhodtseva N. Blood-brain barrier disruption and vascular damage induced by ultrasound bursts combined with microbubbles can be influenced by choice of anesthesia protocol. Ultrasound Med Biol. 2011 Aug; 37(8):1259-70.
    View in: PubMed
  18. Tempany CM, McDannold NJ, Hynynen K, Jolesz FA. Focused ultrasound surgery in oncology: overview and principles. Radiology. 2011 Apr; 259(1):39-56.
    View in: PubMed
  19. Yuan J, Mei CS, Madore B, McDannold NJ, Panych LP. Fast fat-suppressed reduced field-of-view temperature mapping using 2DRF excitation pulses. J Magn Reson. 2011 May; 210(1):38-43.
    View in: PubMed
  20. Yoo SS, Bystritsky A, Lee JH, Zhang Y, Fischer K, Min BK, McDannold NJ, Pascual-Leone A, Jolesz FA. Focused ultrasound modulates region-specific brain activity. Neuroimage. 2011 Jun 1; 56(3):1267-75.
    View in: PubMed
  21. Mei CS, Panych LP, Yuan J, McDannold NJ, Treat LH, Jing Y, Madore B. Combining two-dimensional spatially selective RF excitation, parallel imaging, and UNFOLD for accelerated MR thermometry imaging. Magn Reson Med. 2011 Jul; 66(1):112-22.
    View in: PubMed
  22. McDannold N, Park EJ, Mei CS, Zadicario E, Jolesz F. Evaluation of three-dimensional temperature distributions produced by a low-frequency transcranial focused ultrasound system within ex vivo human skulls. IEEE Trans Ultrason Ferroelectr Freq Control. 2010 Sep; 57(9):1967-76.
    View in: PubMed
  23. McDannold N, Clement GT, Black P, Jolesz F, Hynynen K. Transcranial magnetic resonance imaging- guided focused ultrasound surgery of brain tumors: initial findings in 3 patients. Neurosurgery. 2010 Feb; 66(2):323-32; discussion 332.
    View in: PubMed
  24. Fischer K, McDannold NJ, Zhang Y, Kardos M, Szabo A, Szabo A, Reusz GS, Jolesz FA. Renal ultrafiltration changes induced by focused US. Radiology. 2009 Dec; 253(3):697-705.
    View in: PubMed
  25. Shen SH, Fennessy F, McDannold N, Jolesz F, Tempany C. Image-guided thermal therapy of uterine fibroids. Semin Ultrasound CT MR. 2009 Apr; 30(2):91-104.
    View in: PubMed
  26. Pilatou MC, Stewart EA, Maier SE, Fennessy FM, Hynynen K, Tempany CM, McDannold N. MRI-based thermal dosimetry and diffusion-weighted imaging of MRI-guided focused ultrasound thermal ablation of uterine fibroids. J Magn Reson Imaging. 2009 Feb; 29(2):404-11.
    View in: PubMed
  27. McDannold N, Tempany C, Jolesz F, Hynynen K. Evaluation of referenceless thermometry in MRI-guided focused ultrasound surgery of uterine fibroids. J Magn Reson Imaging. 2008 Oct; 28(4):1026-32.
    View in: PubMed
  28. Lénárd ZM, McDannold NJ, Fennessy FM, Stewart EA, Jolesz FA, Hynynen K, Tempany CM. Uterine leiomyomas: MR imaging-guided focused ultrasound surgery--imaging predictors of success. Radiology. 2008 Oct; 249(1):187-94.
    View in: PubMed
  29. McDannold N, Maier SE. Magnetic resonance acoustic radiation force imaging. Med Phys. 2008 Aug; 35(8):3748-58.
    View in: PubMed
  30. Raymond SB, Treat LH, Dewey JD, McDannold NJ, Hynynen K, Bacskai BJ. Ultrasound enhanced delivery of molecular imaging and therapeutic agents in Alzheimer's disease mouse models. PLoS One. 2008; 3(5):e2175.
    View in: PubMed
  31. Sheikov N, McDannold N, Sharma S, Hynynen K. Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium. Ultrasound Med Biol. 2008 Jul; 34(7):1093-104.
    View in: PubMed
  32. Vykhodtseva N, McDannold N, Hynynen K. Progress and problems in the application of focused ultrasound for blood-brain barrier disruption. Ultrasonics. 2008 Aug; 48(4):279-96.
    View in: PubMed
  33. McDannold N, Vykhodtseva N, Hynynen K. Effects of acoustic parameters and ultrasound contrast agent dose on focused-ultrasound induced blood-brain barrier disruption. Ultrasound Med Biol. 2008 Jun; 34(6):930-7.
    View in: PubMed
  34. Jolesz FA, McDannold N. Current status and future potential of MRI-guided focused ultrasound surgery. J Magn Reson Imaging. 2008 Feb; 27(2):391-9.
    View in: PubMed
  35. McDannold N, Vykhodtseva N, Hynynen K. Blood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index. Ultrasound Med Biol. 2008 May; 34(5):834-40.
    View in: PubMed
  36. McDannold N, Barnes AS, Rybicki FJ, Oshio K, Chen NK, Hynynen K, Mulkern RV. Temperature mapping considerations in the breast with line scan echo planar spectroscopic imaging. Magn Reson Med. 2007 Dec; 58(6):1117-23.
    View in: PubMed
  37. Treat LH, McDannold N, Vykhodtseva N, Zhang Y, Tam K, Hynynen K. Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI-guided focused ultrasound. Int J Cancer. 2007 Aug 15; 121(4):901-7.
    View in: PubMed
  38. Fennessy FM, Tempany CM, McDannold NJ, So MJ, Hesley G, Gostout B, Kim HS, Holland GA, Sarti DA, Hynynen K, Jolesz FA, Stewart EA. Uterine leiomyomas: MR imaging-guided focused ultrasound surgery--results of different treatment protocols. Radiology. 2007 Jun; 243(3):885-93.
    View in: PubMed
  39. McDannold N, Vykhodtseva N, Hynynen K. Use of ultrasound pulses combined with Definity for targeted blood-brain barrier disruption: a feasibility study. Ultrasound Med Biol. 2007 Apr; 33(4):584-90.
    View in: PubMed
  40. Vykhodtseva N, McDannold N, Hynynen K. Induction of apoptosis in vivo in the rabbit brain with focused ultrasound and Optison. Ultrasound Med Biol. 2006 Dec; 32(12):1923-9.
    View in: PubMed
  41. McDannold N, Hynynen K. Quality assurance and system stability of a clinical MRI-guided focused ultrasound system: four-year experience. Med Phys. 2006 Nov; 33(11):4307-13.
    View in: PubMed
  42. McDannold NJ, Vykhodtseva NI, Hynynen K. Microbubble contrast agent with focused ultrasound to create brain lesions at low power levels: MR imaging and histologic study in rabbits. Radiology. 2006 Oct; 241(1):95-106.
    View in: PubMed
  43. Sheikov N, McDannold N, Jolesz F, Zhang YZ, Tam K, Hynynen K. Brain arterioles show more active vesicular transport of blood-borne tracer molecules than capillaries and venules after focused ultrasound-evoked opening of the blood-brain barrier. Ultrasound Med Biol. 2006 Sep; 32(9):1399-409.
    View in: PubMed
  44. Dimaio SP, Archip N, Hata N, Talos IF, Warfield SK, Majumdar A, Mcdannold N, Hynynen K, Morrison PR, Wells WM, Kacher DF, Ellis RE, Golby AJ, Black PM, Jolesz FA, Kikinis R. Image-guided neurosurgery at Brigham and Women's Hospital. IEEE Eng Med Biol Mag. 2006 Sep-Oct; 25(5):67-73.
    View in: PubMed
  45. Hynynen K, McDannold N, Vykhodtseva N, Raymond S, Weissleder R, Jolesz FA, Sheikov N. Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery. J Neurosurg. 2006 Sep; 105(3):445-54.
    View in: PubMed
  46. So MJ, Fennessy FM, Zou KH, McDannold N, Hynynen K, Jolesz FA, Stewart EA, Rybicki FJ, Tempany CM. Does the phase of menstrual cycle affect MR-guided focused ultrasound surgery of uterine leiomyomas? Eur J Radiol. 2006 Aug; 59(2):203-7.
    View in: PubMed
  47. Kinoshita M, McDannold N, Jolesz FA, Hynynen K. Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption. Proc Natl Acad Sci U S A. 2006 Aug 1; 103(31):11719-23.
    View in: PubMed
  48. McDannold N, Tempany CM, Fennessy FM, So MJ, Rybicki FJ, Stewart EA, Jolesz FA, Hynynen K. Uterine leiomyomas: MR imaging-based thermometry and thermal dosimetry during focused ultrasound thermal ablation. Radiology. 2006 Jul; 240(1):263-72.
    View in: PubMed
  49. Hynynen K, McDannold N, Clement G, Jolesz FA, Zadicario E, Killiany R, Moore T, Rosen D. Pre-clinical testing of a phased array ultrasound system for MRI-guided noninvasive surgery of the brain--a primate study. Eur J Radiol. 2006 Aug; 59(2):149-56.
    View in: PubMed
  50. McDannold N, Vykhodtseva N, Hynynen K. Targeted disruption of the blood-brain barrier with focused ultrasound: association with cavitation activity. Phys Med Biol. 2006 Feb 21; 51(4):793-807.
    View in: PubMed
  51. McDannold N, Vykhodtseva N, Hynynen K. Targeted disruption of the blood-brain bar-rier with focused ultrasound: association with cavitation activity. Phys Med Biol 2006. 2006; 51(4):793-807.
  52. Kinoshita M, McDannold N, Jolesz FA, Hynynen K. Targeted delivery of antibodies through the blood-brain barrier by MRI-guided focused ultrasound. Biochem Biophys Res Commun. 2006 Feb 24; 340(4):1085-90.
    View in: PubMed
  53. McDannold N, Vykhodtseva N, Raymond S, Jolesz FA, Hynynen K. MRI-guided targeted blood-brain barrier disruption with focused ultrasound: histological findings in rabbits. Ultrasound Med Biol. 2005 Nov; 31(11):1527-37.
    View in: PubMed
  54. McDannold N. Quantitative MRI-based temperature mapping based on the proton resonant frequency shift: review of validation studies. Int J Hyperthermia. 2005 Sep; 21(6):533-46.
    View in: PubMed
  55. Clement GT, White PJ, King RL, McDannold N, Hynynen K. A magnetic resonance imaging-compatible, large-scale array for trans-skull ultrasound surgery and therapy. J Ultrasound Med. 2005 Aug; 24(8):1117-25.
    View in: PubMed
  56. Jolesz FA, Hynynen K, McDannold N, Tempany C. MR imaging-controlled focused ultrasound ablation: a noninvasive image-guided surgery. Magn Reson Imaging Clin N Am. 2005 Aug; 13(3):545-60.
    View in: PubMed
  57. Silcox CE, Smith RC, King R, McDannold N, Bromley P, Walsh K, Hynynen K. MRI-guided ultrasonic heating allows spatial control of exogenous luciferase in canine prostate. Ultrasound Med Biol. 2005 Jul; 31(7):965-70.
    View in: PubMed
  58. Liu HL, McDannold N, Hynynen K. Focal beam distortion and treatment planning in abdominal focused ultrasound surgery. Med Phys. 2005 May; 32(5):1270-80.
    View in: PubMed
  59. Hynynen K, McDannold N, Sheikov NA, Jolesz FA, Vykhodtseva N. Local and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications. Neuroimage. 2005 Jan 1; 24(1):12-20.
    View in: PubMed
  60. Hindley J, Gedroyc WM, Regan L, Stewart E, Tempany C, Hynyen K, Hynnen K, Mcdannold N, Macdanold N, Inbar Y, Itzchak Y, Rabinovici J, Kim HS, Kim K, Geschwind JF, Hesley G, Gostout B, Gostout B, Ehrenstein T, Hengst S, Sklair-Levy M, Shushan A, Jolesz F. MRI guidance of focused ultrasound therapy of uterine fibroids: early results. AJR Am J Roentgenol. 2004 Dec; 183(6):1713-9.
    View in: PubMed
  61. Hynynen K, McDannold N. MRI guided and monitored focused ultrasound thermal ablation methods: a review of progress. Int J Hyperthermia. 2004 Nov; 20(7):725-37.
    View in: PubMed
  62. Jolesz FA, Hynynen K, McDannold N, Freundlich D, Kopelman D. Noninvasive thermal ablation of hepatocellular carcinoma by using magnetic resonance imaging-guided focused ultrasound. Gastroenterology. 2004 Nov; 127(5 Suppl 1):S242-7.
    View in: PubMed
  63. Hynynen K, Clement GT, McDannold N, Vykhodtseva N, King R, White PJ, Vitek S, Jolesz FA. 500-element ultrasound phased array system for noninvasive focal surgery of the brain: a preliminary rabbit study with ex vivo human skulls. Magn Reson Med. 2004 Jul; 52(1):100-7.
    View in: PubMed
  64. Sheikov N, McDannold N, Vykhodtseva N, Jolesz F, Hynynen K. Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles. Ultrasound Med Biol. 2004 Jul; 30(7):979-89.
    View in: PubMed
  65. McDannold N, King RL, Hynynen K. MRI monitoring of heating produced by ultrasound absorption in the skull: in vivo study in pigs. Magn Reson Med. 2004 May; 51(5):1061-5.
    View in: PubMed
  66. McDannold N, Vykhodtseva N, Jolesz FA, Hynynen K. MRI investigation of the threshold for thermally induced blood-brain barrier disruption and brain tissue damage in the rabbit brain. Magn Reson Med. 2004 May; 51(5):913-23.
    View in: PubMed
  67. McDannold N, Fossheim SL, Rasmussen H, Martin H, Vykhodtseva N, Hynynen K. Heat-activated liposomal MR contrast agent: initial in vivo results in rabbit liver and kidney. Radiology. 2004 Mar; 230(3):743-52.
    View in: PubMed
  68. McDannold N, King R, Hynynen K. MRI-monitoring of heating produced by ultrasound absorption in the skull: in vivo study in pigs. Magn Reson Med. 2004; 51(5):1061-1065.
  69. Hynynen K, McDannold N. Focused ultrasound for the treatment of patients with cancer. DeVita VT, Hellman S, Rosenberg SA, editors. Progress in Oncology. 2004; 267-287 (in press).
  70. Hynynen K, McDannold N, Vykhodtseva N, Jolesz FA . Image guided focal opening of the blood brain barrier by low frequency transkull ultrasound exposures. Proceedings of the RSNA. 2003.
  71. Vykhodtseva N, McDannold N, Agabian S, Hynynen K. Histology findings after ultrasound exposure of the brain with ultrasound contrast agent- role of ischemia and apoptosis. Proceedings of the 3rd International Symposium on Therapeutic Ultrasound. 2003; 80-85.
  72. Hynynen K, Clement G, McDannold N, Connor C, Jolesz FA, Vykhodtseva N. The feasibility of targeted treatments of the brain. Proceedings of the 3rd International Symposium on Therapeutic Ultrasound. 2003.
  73. McDannold N, Vykhodtseva N, Martin H, Jolesz F, Hynynen K. Validation of MRI-derived temperature and thermal dosimetry measurements for guiding focused ultrasound thermal ablation. Proceedings of the 3rd International Symposium on Therapeutic Ultrasound. 2003; 234-239.
  74. McDannold N, Moss M, Killiany R, Rosene DL, King RL, Jolesz FA, Hynynen K. MRI-guided focused ultrasound surgery in the brain: tests in a primate model. Magn Reson Med. 2003 Jun; 49(6):1188-91.
    View in: PubMed
  75. Hynynen K, McDannold N, Martin H, Jolesz FA, Vykhodtseva N. The threshold for brain damage in rabbits induced by bursts of ultrasound in the presence of an ultrasound contrast agent (Optison). Ultrasound Med Biol. 2003 Mar; 29(3):473-81.
    View in: PubMed
  76. Tempany CM, Stewart EA, McDannold N, Quade BJ, Jolesz FA, Hynynen K. MR imaging-guided focused ultrasound surgery of uterine leiomyomas: a feasibility study. Radiology. 2003 Mar; 226(3):897-905.
    View in: PubMed
  77. Hynynen KH, McDannold NJ. Blood-brain barrier opening. 2003.
  78. Vykhodtseva N, McDannold N, Hynynen K. Threshold damage induced during thermal therapy with focused ultrasound: histological investigation in the normal rabbit brain. Proceedings of the 47th annual convention of the AIUM. 2003.
  79. Hynynen K, McDannold N, Martin H, Jolesz FA, Vykhodtseva N. The threshold for brain damage in rabbits induced by bursts of ultrasound in the presence of an ultrasound contrast agent (Optison®). Ultrasound Med Biol. 2003; 29(3):473-81.
  80. Hynynen K, Clement G, McDannold N, King R, White PJ, Vitek S, Jolesz F. A 500 element ultrasound phased array system for noninvasive focal surgery of the brain- a preliminary rabbit study with ex vivo human skulls. Proceedings of the Ultrasonics Symposium. 2003.
  81. Silcox C, Smith RC, King R, McDannold N, Bromley P, Walsh K, Hynynen K. MRI-monitored ultrasonic heating allows for the spatially controlled in vivo expression of the transgene luciferase in canine prostate. Proceedings of the Ultrasonics Symposium. 2003.
  82. Tempany C, Stewart E, McDannold N, Quade B, Jolesz F, Hynynen K. MRI guided focused ultrasound surgery (FUS) of uterine leiomyomas: a feasibility study. Radiology. 2003; 227:897-905.
  83. Hynynen K, Clement G, McDannold N, King R, White PJ, Jolesz F, Vitek S, Zadicario E. Pre-clinical testing of a phased array ultrasound system for MRI-guided noninvasive surgery of the brain. Proceedings of the Eleventh Meeting of the International Society for Magnetic Resonance in Medicine. 2003; 77.
  84. McDannold N, Vykhodtseva N, Martin H, Jolesz F, Hynynen K. Investigation of the threshold for tissue damage in the rabbit brain using MRI-derived temperature information. Proceedings of the Eleventh Meeting of the International Society for Magnetic Resonance in Medicine. 2003; 1208.
  85. Hynynen K, McDannold N, Vykhodtseva N, Jolesz FA. Non-invasive opening of BBB by focused ultrasound. Acta Neurochir Suppl. 2003; 86:555-8.
    View in: PubMed
  86. Fennessy F, McDannold N, Stewart E, Haker S, Zou K, Hynynen K, Jolesz F, Tempany C. Nominal orientation of MRI-guided focused ultrasound treatment of uterine leiomyomas induces greater leiomyoma necrosis. Proceedings of the Eleventh Meeting of the International Society for Magnetic Resonance in Medicine. 2003; 1215.
  87. Stewart EA, Gedroyc WMH, Tempany CMC, Quade BJ, Inbar Y, Ehrenstein T, Shushan A, Hindley JT, Goldin RD, David M, Sklair M, Rabinovici J, Itzchak Y, McDannold N, Hynynen K, Jolesz FA, Oestmann JW, Yagel S, Revel A, Gomori M, Regan L. Focused ultrasound treatment of uterine fibroids: safety and feasibility of a noninvasive thermoablative technique. Am J Obstet Gynecol. 2003; 189(1):48-54.
  88. Hynynen K, Clement G, McDannold N, Connor C, Vykhodtseva N. Large ultrasound phased arrays for noninvasive focal treatments. Proceedings of the 145th Meeting of the Acoustical Society of America. 2003; 2280.
  89. McDannold N, Tempany CM, Stewart EA, Jolesz F, Hynynen K. Thermal dosimetry during MRI-guided focused ultrasound surgery in uterine fibroids. Proceedings of the Eleventh Meeting of the International Society for Magnetic Resonance in Medicine. 2003; 1207.
  90. McDannold, N, Vykhodtseva N, Martin H, Hynynen K. Investigation of the thermal threshold for brain tissue damage using MRI-derived thermal dosimetry in the rabbit brain. Proceedings of the Brigham and Women’s Hospital Research Fellow Poster Exhibition. 2003; 28.
  91. Sokka S, McDannold N, Hynynen K. Optimization, mechanisms, monitoring and control of cavitation-enhanced heating in vivo. Proceedings of the Ultrasonics Symposium. 2003.
  92. McDannold N, Vykhodtseva N, Hynynen K. Threshold damage induced during thermal therapy with focused ultrasound: correlation with magnetic resonance imaging and thermometry. Proceedings of the 47th annual convention of the AIUM. 2003.
  93. Jolesz FA, Talos IF, Schwartz RB, Mamata H, Kacher DF, Hynynen K, McDannold N, Saivironporn P, Zao L. Intraoperative magnetic resonance imaging and magnetic resonance imaging-guided therapy for brain tumors. Neuroimaging Clin N Am. 2002 Nov; 12(4):665-83.
    View in: PubMed
  94. McDannold N, King RL, Jolesz FA, Hynynen K. The use of quantitative temperature images to predict the optimal power for focused ultrasound surgery: in vivo verification in rabbit muscle and brain. Med Phys. 2002 Mar; 29(3):356-65.
    View in: PubMed
  95. Fossheim SL, Rassmussen H, Wiggen UN, Bjornerud A, Rogstad A, Il'yasov KA, Hynynen K, McDannold N, Salomir R, Palussiere J. Thermosensitive paramagnetic liposomes for MRI-guided thermal treatment: Feasibility studies in various animal models. Proceedings of the Eighth Bi-Annual Conference on MR and Intermodality Contrast Agent Research. 2002.
  96. Vykhodtseva N, McDannold N, Sheikov N, Martin H, Jolesz F, Hynynen K. Effects of short-pulsed focused ultrasound on the brain vasculature in the presence of an US contrast agent: Study on rabbit brain in vivo. Proceedings of the Workshop on MRI-Guided Focused Ultrasound Surgery. 2002; 67-70.
  97. Sokka S, King R, McDannold N, Hynynen K. Gas-bubble enhanced beating in rabbit thigh in vivo. Proceedings of the Ultrasonics Symposium. 2002; 1415-1418.
  98. Vykhodtseva N, McDannold N, Sheikov N, Martin H, Jolesz F, Hynynen K. Focused ultrasound induced vascular damage in the presence of cavitation bubbles: A histological study on the rabbit brain. Proceedings of the 46th annual Meeting of the AIUM. 2002.
  99. Hynynen K, Tempany CM, Stewart E, McDannold N, Quade B, Yanaushpolsky E, Jolesz FA. Thermal monitoring of clinical focused ultrasound treatments of uterine fibroids. Proceedings of the Tenth Meeting of the International Society for Magnetic Resonance in Medicine. 2002; 239.
  100. McDannold N, Martin H, Jolesz FA, Hynynen K. Long-term survival after focused ultrasound surgery in tumors guided by MRI: Preliminary results. Proceedings of the Tenth Meeting of the International Society for Magnetic Resonance in Medicine. 2002; 247.
  101. McDannold N, Killiany R, Moss M, Jolesz FA, Hynynen K. MRI-guided focused ultrasound surgery in the brain: Tests in a primate model. Proceedings of the Tenth Meeting of the International Society for Magnetic Resonance in Medicine. 2002; 2201.
  102. Clement G, McDannold N, White J, Vykhodtseva N, Martin H, Hynynen K. MRI-guided focused ultrasound through the human skull. Proceedings of the Tenth Meeting of the International Society for Magnetic Resonance in Medicine. 2002; 2225.
  103. Hynynen K, McDannold N, Sheikov N, Jolesz F, Vykhodtseva N. The Role of Cavitation in the Opening of the Blood-Brain Barrier by Focused Ultrasound. Proceedings of the Ultrasonics Symposium. 2002.
  104. Hynynen K, McDannold N, Martin H, Sheikov N, Jolesz F., Vykhodtseva N. Ultrasound-induced focal blood-brain barrier opening for targeted drug delivery. Proceedings of the 47th annual convention of the AIUM. 2002.
  105. Fossheim SL, Rasmussen H, Il'yasov KA, Rogstad A, Wiggen UN, Bjornerud A, Martin H, McDannold N, Hynynen K. Paramagnetic liposomes as thermosensitive probes for MRI-guided thermal treatments: Feasibility studies in various animal models. Proceedings of the Workshop on MRI-Guided Focused Ultrasound Surgery. 2002; 40-2.
  106. McDannold N, Fossheim SL, Rassmussen H, Martin H, Hynynen K. In vivo tests of temperature-activated paramagnetic liposome MRI contrast agent. Proceedings of the RSNA. 2002.
  107. Vykhodtseva N, McDannold N, Hynynen K. Effects of pulsed focused ultrasound at pressures beyond the cavitation threshold: Histological study on rabbit brain in vivo. Proceedings of the 16th International Symposium on Nonlinear Acoustics. 2002; 473-6.
  108. Hynynen K, McDannold N, Josphson L, Vykhodtseva N, Weisleder R, Jolesz FA. Noninvasive MRI-guided focal opening of the blood brain barrier: Demonstration of large particle penetration. Proceedings of the Tenth Meeting of the International Society for Magnetic Resonance in Medicine. 2002; 332.
  109. Vykhodtseva N, McDannold N, Hynynen K. Effects of cavitation induced by low-power focused ultrasound in the presence of an US contrast agent: Study on rabbit brain in vivo. Proceedings of the 16th International Symposium on Nonlinear Acoustics. 2002; 441-4.
  110. McDannold, N. MRI monitoring of high temperature ultrasound therapy (PhD Thesis). 2001.
  111. Hynynen K, McDannold N, Vykhodtseva N, Jolesz FA. Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbits. Radiology. 2001 Sep; 220(3):640-6.
    View in: PubMed
  112. Mahoney K, Fjield T, Mcdannold N, Clement G, Hynynen K. Comparison of modelled and observed in vivo temperature elevations induced by focused ultrasound: implications for treatment planning. Phys Med Biol. 2001 Jul; 46(7):1785-98.
    View in: PubMed
  113. Hynynen K, Pomeroy O, Smith DN, Huber PE, McDannold NJ, Kettenbach J, Baum J, Singer S, Jolesz FA. MR imaging-guided focused ultrasound surgery of fibroadenomas in the breast: a feasibility study. Radiology. 2001 Apr; 219(1):176-85.
    View in: PubMed
  114. McDannold N, Hynynen K, Jolesz F. MRI monitoring of the thermal ablation of tissue: effects of long exposure times. J Magn Reson Imaging. 2001 Mar; 13(3):421-7.
    View in: PubMed
  115. McDannold N, Hynynen K, Oshio K, Mulkern RV. Temperature monitoring with line scan echo planar spectroscopic imaging. Med Phys. 2001 Mar; 28(3):346-55.
    View in: PubMed
  116. Hynynen K, McDannold N, Vykhodtseva N, Jolesz FA. Noninvasive MRI-guided focal opening of blood brain barrier. Proceedings of the Ninth Meeting of the International Society for Magnetic Resonance in Medicine. 2001; 320.
  117. Kuroda K, Mulkern RV, Oshio K, McDannold N, Hynynen K, Toshiharu N, Okada T, Matsumura A, Yanaka K, Jolesz F. Feasibility of internally-referenced temperature imaging using metabolite signals. Proceedings of the Ninth Meeting of the International Society for Magnetic Resonance in Medicine. 2001; 2189.
  118. Hynynen K, McDannold N, King R, Martin H, Vykhodtseva N, Jolesz F. In vivo tests of a noninvasive large-scale phased array system for deep ultrasound surgery under MRI control. Proceedings of the 17th International Congress on Acoustics. 2001.
  119. McDannold NJ, Panych LP, Zhao L, Jolesz FA, Hynynen K. Temperature monitoring with multiple phase-encode and slice select dimensions during focused ultrasound surgery. Proceedings of the Ninth Meeting of the International Society for Magnetic Resonance in Medicine. 2001; 2191.
  120. Tempany C, Stewart E, McDannold N, Quade B, Jolesz F, Hynynen K. MR imaging-guided focused ultrasound surgery of leiomyoma of the uterus: early experience. Proceedings of the RSNA. 2001.
  121. Vykhodtseva N, McDannold N, Martin H, Bronson RT, Hynynen K. Apoptosis in ultrasound-produced threshold lesions in the rabbit brain. Ultrasound Med Biol. 2001 Jan; 27(1):111-7.
    View in: PubMed
  122. McDannold N, Jolesz FA, Hynynen K. The use of MRI-derived thermometry for treatment planning and monitoring of focused ultrasound surgery. Proceedings of the First International Workshop on the Application of High Intensity Focused Ultrasound (HIFU) in Medicine. 2001; 43-5.
  123. Thierman J, McDannold N, Konofagou E, Hynynen K. New Directions in US and MRI thermal monitoring. Proceedings of the 48th Meeting of the RRS/19th Meeting of the NAHS. 2001; 76.
  124. Hynynen K, McDannold N, Vykhodtseva N, Jolesz F . Brain damage induced by low power ultrasound exposures after an injection of ultrasound contrast agent with preformed gas bubbles. Proceedings of the RSNA. 2001.
  125. Hynynen K, McDannold NJ, King RL, Martin H, Raymond JL, Jolesz FA. Clinical large-scale MR-guided ultrasound phased array system. Proceedings of the 48th Meeting of the RRS/19th Meeting of the NAHS. 2001; 65.
  126. McDannold NJ, Mulkern RV, Kuroda K, Hynynen K. Is absolute temperature measurement in the breast with H1 spectroscopic imaging feasible?. Proceedings of the Ninth Meeting of the International Society for Magnetic Resonance in Medicine. 2001; 2190.
  127. Hynynen K, McDannold N, Vykhodtseva N, Sheikov N, Jolesz F. MRI guided focused ultrasound opening of blood brain barrier. Proceedings of the 142nd Meeting of the Acoustical Society of America. 2001; 2642.
  128. McDannold NJ, Hynynen K, Jolesz FA. MRI monitoring of focused ultrasound surgery in tumors with multi-slice echo-planar imaging in rabbits. Proceedings of the Ninth Meeting of the International Society for Magnetic Resonance in Medicine. 2001; 2208.
  129. Hynynen K, McDannold N, Sheikov N, Jolesz F, Vykhodtseva N. Noninvasive MRI-guided focal opening of blood brain barrier: Potential use for targeted drug delivery. Proceedings of the First International Workshop on the Application of High Intensity Focused Ultrasound (HIFU) in Medicine. 2001; 19-21.
  130. Hynynen K, McDannold N, Jolesz F, Vykhodtseva N. Noninvasive MRI-guided focal opening of blood brain barrier: Potential use for targeted drug delivery. Proceedings of the 17th International Congress on Acoustics. 2001.
  131. McDannold NJ, King RL, Jolesz FA, Hynynen KH. Usefulness of MR imaging-derived thermometry and dosimetry in determining the threshold for tissue damage induced by thermal surgery in rabbits. Radiology. 2000 Aug; 216(2):517-23.
    View in: PubMed
  132. McDannold NJ, Jolesz FA. Magnetic resonance image-guided thermal ablations. Top Magn Reson Imaging. 2000 Jun; 11(3):191-202.
    View in: PubMed
  133. Hynynen K, McDannold N, Mulkern RV, Jolesz FA. Temperature monitoring in fat with MRI. Magn Reson Med. 2000 Jun; 43(6):901-4.
    View in: PubMed
  134. McDannold NJ, Jolesz FA, Hynynen K. 3D MRI-derived thermometry and dosimetry. Proceedings of the Eighth Meeting of the International Society for Magnetic Resonance in Medicine. 2000; 1337.
  135. Smith DN, Hynynen K, Pomeroy OH, Huber PE, McDannold NJ, Kettenbach J. MRI guided focused ultrasound surgery (FUS) of fibroadenomas in the breast. Proceedings of the RSNA. 2000.
  136. Hynynen K, McDannold NJ, Smith DN, Jolesz FA. The clinical feasibility of noninvasive online thermal exposure quantification by using multi-time point MRI thermometry. Proceedings of the RSNA. 2000.
  137. Kuroda K, Jinzaki M, McDannold NJ, Nakai T, Moriya T, Hynynen K, Jolesz FA. Internally-referenced measurement of prostate temperature using metabolite signals. Proceedings of the Eighth Meeting of the International Society for Magnetic Resonance in Medicine. 2000; 49.
  138. McDannold NJ, Hynynen K, Mulkern RV. Temperature calibration of a line scan echo planar spectroscopic imaging (LSEPSI) sequence. Proceedings of the RSNA. 2000.
  139. Mulkern RV, McDannold NJ, Oshio K, Hynynen K. Temperature monitoring with line scan echo planar spectroscopic imaging (LSEPSI). Proceedings of the 42nd annual Meeting of the AAPM. 2000.
  140. McDannold NJ, Mulkern RV, Hynynen K. The feasibility of monitoring of hyperthermia in prostate with chemical-shift based MRI thermometry. Proceedings of the Eighth Meeting of the International Society for Magnetic Resonance in Medicine. 2000; 1350.
  141. Hynynen K, McDannold NJ, Jolesz FA, Vykhodtseva NI. MRI guided focal blood brain opening by using focused ultrasound. Proceedings of the Ultrasonics Symposium. 2000; 1417-20.
  142. Sokka SD, King RL, McDannold NJ, Hynynen K. Design and evaluation of a linear intracavitary ultrasound phased array for MRI-guided prostate ablative therapies. Proceedings of the Ultrasonics Symposium. 2000; 1435-8.
  143. Hynynen K, McDannold NJ, Mahoney K, Jolesz FA. MRI thermal dosimetry during focused ultrasound surgery with multiple sonications. Proceedings of the Eighth Meeting of the International Society for Magnetic Resonance in Medicine. 2000; 1357.
  144. McDannold NJ, Jolesz FA, Hynynen KH. Determination of the optimal delay between sonications during focused ultrasound surgery in rabbits by using MR imaging to monitor thermal buildup in vivo. Radiology. 1999 May; 211(2):419-26.
    View in: PubMed
  145. Hynynen K, Vykhodtseva NI, McDannold NJ, Bronson R, Jolesz FA. Image guided thermal therapy. Proceedings of the Eleventh International Congress of Radiation Research. 1999; 845-8.
  146. Hynynen K, McDannold NJ, Jolesz FA. The feasibility of MRI control of ultrasound surgery of large tumors. Proceedings of the Seventh Meeting of the International Society for Magnetic Resonance in Medicine. 1999; 1943.
  147. Daum DR, Smith NB, McDannold NJ, Hynynen K. MR guided non-invasive thermal coagulation of in vivo liver tissue using an ultrasonic phased array. Proceedings of SPIE Photonics West. 1999.
  148. Hynynen K, Sun J, Clement G, Thierman J, Daum D, Vykhodtseva NI, McDannold NJ. Phased array development for noninvasive focused ultrasound therapy of brain and liver. Proceedings of the First Joint BMES/EMBS Conference. 1999; 1270.
  149. Mulkern RV, McDannold NJ, Hynynen K, Fielding J, Panych LP, Jolesz FA, Weingand K. Temperature distribution changes in low back muscles during applied topical heat: A magnetic resonance thermometry study. Proceedings of the Seventh Meeting of the International Society for Magnetic Resonance in Medicine. 1999; 1054.
  150. Daum DR, Smith NB, McDannold NJ, Hynynen K. Experimental verification of the advantage of a 256 element ultrasonic phased array for thermal coagulation of deep seated tissue. Proceedings of SPIE Medical Imaging. 1999.
  151. Foldes K, Hynynen K, Shortkroff S, Winalski CS, Collucci V, Koskinen SK, McDannold N, Jolesz F. Magnetic resonance imaging-guided focused ultrasound synovectomy. Scand J Rheumatol. 1999; 28(4):233-7.
    View in: PubMed
  152. McDannold NJ, King RL, Jolesz FA, Hynynen K. The usefulness of temperature sensitive MRI-derived thermal dose for determining the threshold for tissue damage. Proceedings of the Seventh Meeting of the International Society for Magnetic Resonance in Medicine. 1999; 1936.
  153. Mulkern RV, Panych LP, McDannold NJ, Jolesz FA, Hynynen K. Tissue temperature monitoring with multiple gradient-echo imaging sequences. J Magn Reson Imaging. 1998 Mar-Apr; 8(2):493-502.
    View in: PubMed
  154. Hynynen K, Fjield T, Daum D, McDannold NJ, Sun J. Phased array development for noninvasive surgery and therapy. Proceedings of the SPIE. 1998; 84-7.
  155. McDannold NJ, Hynynen K, Wolf D, Wolf G, Jolesz FA. MRI evaluation of thermal ablation of tumors with focused ultrasound. J Magn Reson Imaging. 1998; 8(1):91-100.
  156. Fjield T, McDannold NJ, Silcox C, Hynynen K. In vivo verification of the acoustic model used to predict temperature elevations for MRI guided ultrasound surgery. Proceedings of the Ultrasonics Symposium. 1998; 1415-8.
  157. McDannold NJ, Hynynen K. The use of magnetic resonance imaging to evaluate thermal build-up during focused ultrasound surgery in vivo. Proceedings of the 42nd annual convention of the AIUM. 1998; 69.
  158. McDannold NJ, Hynynen K, Wolf D, Wolf G, Jolesz FA. MRI evaluation of thermal ablation of tumors with focused ultrasound. J Magn Reson Imaging. 1998; 8(1):91-100.
  159. Kettenbach J, Kuroda K, Hata N, Morrison PR, McDannold NJ, Gering P, Saiviroonporn P, Zientara GP, McL.Black P, Kikinis R, Jolesz FA. Laser-induced thermotherapy of cerebral neoplasia under MR tomographic control. Min Invas Ther & Allied Technol. 1998; 7(6):589-98.
  160. MRI evaluation of thermal ablation of tumors with focused ultrasound. J Magn Reson Imaging. 1998 Jan-Feb; 8(1):91-100.
    View in: PubMed
  161. Hynynen K, McDannold NJ, Fjield T, Daum DR. MRI monitoring and control of focused ultrasound surgery. Proceedings of the 16th International Congress on Acoustics/135th Meeting of the Acoustical Society of America. 1998; 2832.
  162. McDannold NJ, Jolesz FA, Hynynen K. The use of MRI in vivo to monitor thermal build-up during focused ultrasound surgery. Proceedings of the Sixth Meeting of the International Society for Magnetic Resonance in Medicine. 1998.
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact Human Resources at faculty_serviceshms.harvard.edu.
McDannold's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
_
Co-Authors
_
Similar People
_
Same Department
Physical Neighbors
_