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Alireza Atri, M.D., PH.D.

TitleClinical Instructor in Neurology
InstitutionMassachusetts General Hospital
DepartmentNeurology
AddressMassachusetts General Hospital
Neurology Memory Disorders Unit, WACC 830
15 Parkman Street
Boston MA 02114
Phone617/726-1728
Fax617/726-4101

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Rountree SD, Atri A, Lopez OL, Doody RS. Effectiveness of antidementia drugs in delaying Alzheimer's disease progression. Alzheimers Dement. 2013 May; 9(3):338-45.
    View in: PubMed
  2. Mitchell MB, Shaughnessy LW, Shirk SD, Yang FM, Atri A. Neuropsychological test performance and cognitive reserve in healthy aging and the Alzheimer's disease spectrum: a theoretically driven factor analysis. J Int Neuropsychol Soc. 2012 Nov; 18(6):1071-80.
    View in: PubMed
  3. Lindwall M, Cimino CR, Gibbons LE, Mitchell MB, Benitez A, Brown CL, Kennison RF, Shirk SD, Atri A, Robitaille A, Macdonald SW, Zelinski EM, Willis SL, Schaie KW, Johansson B, Praetorius M, Dixon RA, Mungas DM, Hofer SM, Piccinin AM. Dynamic associations of change in physical activity and change in cognitive function: coordinated analyses of four longitudinal studies. J Aging Res. 2012; 2012:493598.
    View in: PubMed
  4. Mitchell MB, Cimino CR, Benitez A, Brown CL, Gibbons LE, Kennison RF, Shirk SD, Atri A, Robitaille A, Macdonald SW, Lindwall M, Zelinski EM, Willis SL, Schaie KW, Johansson B, Dixon RA, Mungas DM, Hofer SM, Piccinin AM. Cognitively Stimulating Activities: Effects on Cognition across Four Studies with up to 21 Years of Longitudinal Data. J Aging Res. 2012; 2012:461592.
    View in: PubMed
  5. Brown CL, Gibbons LE, Kennison RF, Robitaille A, Lindwall M, Mitchell MB, Shirk SD, Atri A, Cimino CR, Benitez A, Macdonald SW, Zelinski EM, Willis SL, Schaie KW, Johansson B, Dixon RA, Mungas DM, Hofer SM, Piccinin AM. Social activity and cognitive functioning over time: a coordinated analysis of four longitudinal studies. J Aging Res. 2012; 2012:287438.
    View in: PubMed
  6. McLaren DG, Sreenivasan A, Diamond EL, Mitchell MB, Van Dijk KR, Deluca AN, O'Brien JL, Rentz DM, Sperling RA, Atri A. Tracking cognitive change over 24 weeks with longitudinal functional magnetic resonance imaging in Alzheimer's disease. Neurodegener Dis. 2012; 9(4):176-86.
    View in: PubMed
  7. Atri A, Rountree SD, Lopez OL, Doody RS. Validity, significance, strengths, limitations, and evidentiary value of real-world clinical data for combination therapy in Alzheimer's disease: comparison of efficacy and effectiveness studies. Neurodegener Dis. 2012; 10(1-4):170-4.
    View in: PubMed
  8. Shirk SD, Mitchell MB, Shaughnessy LW, Sherman JC, Locascio JJ, Weintraub S, Atri A. A web-based normative calculator for the uniform data set (UDS) neuropsychological test battery. Alzheimers Res Ther. 2011; 3(6):32.
    View in: PubMed
  9. Atri A. Effective pharmacological management of Alzheimer's disease. Am J Manag Care. 2011 Nov; 17 Suppl 13:S346-55.
    View in: PubMed
  10. Locascio JJ, Atri A. An overview of longitudinal data analysis methods for neurological research. Dement Geriatr Cogn Dis Extra. 2011 Jan; 1(1):330-57.
    View in: PubMed
  11. Atri A, O'Brien JL, Sreenivasan A, Rastegar S, Salisbury S, DeLuca AN, O'Keefe KM, LaViolette PS, Rentz DM, Locascio JJ, Sperling RA. Test-retest reliability of memory task functional magnetic resonance imaging in Alzheimer disease clinical trials. Arch Neurol. 2011 May; 68(5):599-606.
    View in: PubMed
  12. Rosenbloom MH, Atri A. The evaluation of rapidly progressive dementia. Neurologist. 2011 Mar; 17(2):67-74.
    View in: PubMed
  13. Putcha D, O'Keefe K, LaViolette P, O'Brien J, Greve D, Rentz DM, Locascio J, Atri A, Sperling R. Reliability of functional magnetic resonance imaging associative encoding memory paradigms in non-demented elderly adults. Hum Brain Mapp. 2011 Dec; 32(12):2027-44.
    View in: PubMed
  14. Atri, A, Chang M, Strichartz G. Cholinergic Pharmacology. Principles of Pharmacology: The Pathophysiological Basis for Drug Therapy. Golan et al. Editors. 2011.
  15. Slachevsky A, Muñoz-Neira C, Nuñez-Huasaf J, Stern TA, Blesius CR, Atri A. Late-onset cinephilia and compulsive behaviors: harbingers of frontotemporal dementia. Prim Care Companion CNS Disord. 2011; 13(3).
    View in: PubMed
  16. A. ATRI, J. S. DODD, A. SREENIVASAN, P. VANNINI, J. L. O’BRIEN, P. LAVIOLETTE1, J. J. LOCASCIO1, R. A. SPERLING. A Candidate fMRI Measure Combining Hippocampal and Default Mode Network Activity to Predict Future Memory Performance in Alzheimer’s Disease . Alzheimer's Assoc. ICAD (Int. Conf. on Alzheimers & Assoc. Disorders). 2010; Oral Presentation 02-04-06.
  17. A. ATRI, J.S. DODD, F.M. WANG, J. J. LOCASCIO. Presence of Extrapyramidal Motor Signs Predict Worse Cognitive and Functional Trajectory of Decline in Mild-to-Moderate Alzheimer's . Alzheimer's Assoc. ICAD (Int. Conf. on Alzheimers & Assoc. Disorders). 2010; Poster Presentation P2-125.
  18. Serrano-Pozo A, Vega GL, Lütjohann D, Locascio JJ, Tennis MK, Deng A, Atri A, Hyman BT, Irizarry MC, Growdon JH. Effects of simvastatin on cholesterol metabolism and Alzheimer disease biomarkers. Alzheimer Dis Assoc Disord. 2010 Jul-Sep; 24(3):220-6.
    View in: PubMed
  19. Alireza Atri, Sumer Verma, Sang Yun Kim. Dementia. International Textbook of Geriatric Medicine. Juergen Bludau Editor. 2010; (in press).
  20. J. S. DODD, E. T. CREHAN, A. SREENIVASAN, P. VANNINI, J. L. O’BRIEN, P. LAVIOLETTE1, J. J. LOCASCIO1, R. A. SPERLING, A. ATRI. Candidate prognostic models using fMRI measures to predict future memory performance in Alzheimer’s disease . Society for Neuroscience Abstracts. 2009; Program#/Poster#: 140.18/E20 .
  21. A. SREENIVASAN, E. T. CREHAN, J. S. DODD, E. DIAMOND, J. L. O'BRIEN, P. LAVIOLETTE, D. M. RENTZ, R. A. SPERLING, A. ATRI. Clinico-functional-anatomic relationships in Alzheimer’s disease: fMRI tracks clinical trial memory measures. Society for Neuroscience Abstracts. 2009; Program#/Poster#: 140.17/E19 .
  22. Michael R. Flaherty, B.S., Joseph J. Locascio, Ph.D., and Alireza Atri, M.D., Ph.D. Vitamin E slows functional decline and anti-inflammatories slow cognitive decline in Alzheimer’s Disease . American Geriatrics Society Annual Meeting. 2009; A117.
  23. Atri A, O’Brien J, Rastegar S, DeLuca A, O’Keefe K, LaViolette P, Diamond EL, Salisbury S, Pihlajamaki MM, Locascio JJ, Rentz D, and RA Sperling . Feasibility and Test-retest Reliability of fMRI in an Alzheimer’s Disease Clinical Trial . International Conference on Alzheimer's Disease and Associated Disorders Abstracts; Chicago, IL. 2008; 1561.
  24. Dickerson BC, Bakkour A, Salat DH, Feczko E, Pacheco J, Greve DN, Grodstein F, Wright CI, Blacker D, Rosas HD, Sperling RA, Atri A, Growdon JH, Hyman BT, Morris JC, Fischl B, Buckner RL. The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals. Cereb Cortex. 2009 Mar; 19(3):497-510.
    View in: PubMed
  25. Dickerson BC, Bakkour A, Salat DH, Feczko E, Pacheco J, Greve DN, Grodstein F, Wright CI, Blakcer D, Rosas HD, Sperling RA, Atri A, Growdon JH, Hyman BT, Moris JC, Fischl B, Buckner RL. The Cortical Signature of Alzheimer's Disease: Regionally Specific Cortical Thinning Relates to Symptom Severity in Very Mild to Mild AD Dementia and is Detectable in Asymptomatic Amyloid-Positive Inidividuals. Cerebral Cortex. 2008; epub ahead of print.
  26. Atri A, Shaughnessy LW, Locascio JJ, Growdon JH. Long-term course and effectiveness of combination therapy in Alzheimer disease. Alzheimer Dis Assoc Disord. 2008 Jul-Sep; 22(3):209-21.
    View in: PubMed
  27. Reddy, KS, Kasyer, AS, and Atri, A. . Encephalopathy: Approach to Diagnosis and Care. Hospital Physician Neurology Board Review Manual. 2008; 12(1):1-15.
  28. Dickerson BC, Bakkour A, Salat D, Rosas H, Sperling RA, Atri A, Wright CI, Grodstein F,Blacker D, Growdon JH, Hyman BT, Morris J, Buckner R. . The Cortical Signature ofAlzheimer’s Disease (AD): Reliability and Clinical Validity of This MRI-Based Quantitative Biomarker. American Academy of Neurology Annual Conference Abstracts; Chicago, IL. 2008; P08.054.
  29. Diamond EL, Miller S, Dickerson BC, Atri A, DePeau K, Fenstermacher E, Pihlajamäki M, Celone K, Salisbury S, Gregas M, Rentz D, Sperling RA. Relationship of fMRI activation to clinical trial memory measures in Alzheimer disease. Neurology. 2007 Sep 25; 69(13):1331-41.
    View in: PubMed
  30. Atri A, Diamond E, DePeau K, Salisbury S, Celone K, Miller S, Sardinha L, Gregas M, Pihlajamaki M, Searl M, Rentz D, Sperling RA. FMRI Correlates of Face-Name Encoding Longitudinally Track with Changes in Clinical Trial Memory Measures in Alzheimer’s Disease. American Academy of Neurology Annual Conference Abstracts; Boston, MA. 2007; P08.098.
  31. Atri, A, Chang M, Strichartz G. Cholinergic Pharmacology. Principles of Pharmacology: The Pathophysiological Basis for Drug Therapy. Golan et al. Editors. 2007.
  32. Atri, A. Apparent Diffusion Coefficient on MRI and Mild Cognitive Impairment. Journal Watch Neurology. 2007; 3(213):23-24.
  33. Celone KA, Calhoun VD, Dickerson BC, Atri A, Chua EF, Miller SL, DePeau K, Rentz DM, Selkoe DJ, Blacker D, Albert MS, Sperling RA. Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: an independent component analysis. J Neurosci. 2006 Oct 4; 26(40):10222-31.
    View in: PubMed
  34. Kasyer, AS, and Atri, A. . Approach to the evaluation of encephalopathy. Hospital Physician Neurology Board Review Manual. 2005; 9(4):1-16.
  35. Schon K, Atri A, Hasselmo ME, Tricarico MD, LoPresti ML, Stern CE. Scopolamine reduces persistent activity related to long-term encoding in the parahippocampal gyrus during delayed matching in humans. J Neurosci. 2005 Oct 5; 25(40):9112-23.
    View in: PubMed
  36. Atri, A. Diagnosis of Common Dementias. Neurology Self-Assessment. Hospital Physician. 2005; 41(4):25-26.
  37. Qureshi SA, Atri A . The first case of definite variant Creutzfeldt-Jakob disease in the middle-east. American Academy of Neurology Annual Conference Abstracts; Miami, FL. 2005.
  38. Atri A, Locascio JJ, Lin JM, Yap L, Dickerson BC, Grodstein F, Irizarry MC, Growdon JH, Greenberg SM. Prevalence and effects of lobar microhemorrhages in early-stage dementia. Neurodegener Dis. 2005; 2(6):305-12.
    View in: PubMed
  39. Alexander EK, Marqusee E, Orcutt J, Benson CB, Frates MC, Doubilet PM, Cibas ES, Atri A. Thyroid nodule shape and prediction of malignancy. Thyroid. 2004 Nov; 14(11):953-8.
    View in: PubMed
  40. Atri A, LoPresti ML, Sherman SJ, Schendan HE, Hasselmo ME, Stern CE . Central cholinergic augmentation improves reaction time but not recognition memory in young healthy adults. NeuroRx. 2004; 1(4):509-510.
  41. Atri, A. Sleeping on your cholinesterase-inhibitor: forget about it?. Journal Watch Neurology. 2004; 6(8):60-61.
  42. Atri, A. Expert commentator and interview for >50 local, national & international print, internet, radio, and TV media programs, periodicals, stories and news articles relating to cognitive aging, diagnosis and treatments of dementia and brain injury. 2004.
  43. Atri, A, Stern, CE, and Hasselmo, ME. Invited Comment on NEWS: Could Alzheimer’s Drugs Mean “Good Night” to Good Memory?. 2004.
  44. Atri A, Sherman S, Norman KA, Kirchhoff BA, Nicolas MM, Greicius MD, Cramer SC, Breiter HC, Hasselmo ME, Stern CE. Blockade of central cholinergic receptors impairs new learning and increases proactive interference in a word paired-associate memory task. Behav Neurosci. 2004 Feb; 118(1):223-36.
    View in: PubMed
  45. Atri A, Sheen V. Cavernous sinus syndrome and headache due to bilateral carotid artery aneurysms. Arch Neurol. 2003 Sep; 60(9):1327-8.
    View in: PubMed
  46. Sherman SJ, Atri A, Hasselmo ME, Stern CE, Howard MW. Scopolamine impairs human recognition memory: data and modeling. Behav Neurosci. 2003 Jun; 117(3):526-39.
    View in: PubMed
  47. Lee FS, Chu FK, Tackley M, Wu AD, Atri A, Wessels MR. Human granulocytic ehrlichiosis presenting as facial diplegia in a 42-year-old woman. Clin Infect Dis. 2000 Nov; 31(5):1288-91.
    View in: PubMed
  48. Atri, A. Clinical Microbiology and Immunology. First Aid for the USMLE Step 1. Amin, C., Bushan, V., and Le, T., Editors. 1996; 105-131.
  49. Atri, A. Clinical Pharmacology. First Aid for the USMLE Step 1. Amin, C., Bushan, V., and Le, T., Editors. 1996; 161-193.
  50. Atri A, Amundson J, Clapham D, Sneyd J. A single-pool model for intracellular calcium oscillations and waves in the Xenopus laevis oocyte. Biophys J. 1993 Oct; 65(4):1727-39.
    View in: PubMed
  51. Atri, A, Sneyd, J. A mathematical model for the formation of the dental determinant in the Alligator. Ursus Medicus. 1993; (2):41-46.
  52. Sneyd, J, Atri, A, Ferguson, MWJ, Lewis, MA, Seward, W, Murray, JD. A model for the spatial patterning of teeth primordia in the Alligator: initiation of the dental determinant. J Theo Biol. 1993; (165):633-658.
  53. Sneyd, J, Atri, A. Curvature dependence of a model for calcium wave propagation. Physica D. 1993; 65(4):365-372.
  54. Selected from over 50 scientific abstracts since. 1991.
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