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Last Name

Huixian Gan, M.D.

TitleClinical Instructor in Medicine
InstitutionBrigham and Women's Hospital
AddressBrigham and Women's Hospital
Smith Bldg , Rm 528
1 Jimmy Fund Way
Boston MA 02115

 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Nishimura T, Zhao X, Gan H, Koyasu S, Remold HG. The prostaglandin E2 receptor EP4 is integral to a positive feedback loop for prostaglandin E2 production in human macrophages infected with Mycobacterium tuberculosis. FASEB J. 2013 Sep; 27(9):3827-36.
    View in: PubMed
  2. Behar SM, Martin CJ, Booty MG, Nishimura T, Zhao X, Gan HX, Divangahi M, Remold HG. Apoptosis is an innate defense function of macrophages against Mycobacterium tuberculosis. Mucosal Immunol. 2011 May; 4(3):279-87.
    View in: PubMed
  3. Divangahi M, Chen M, Gan H, Desjardins D, Hickman TT, Lee DM, Fortune S, Behar SM, Remold HG. Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair. Nat Immunol. 2009 Aug; 10(8):899-906.
    View in: PubMed
  4. Chen M, Divangahi M, Gan H, Shin DS, Hong S, Lee DM, Serhan CN, Behar SM, Remold HG. Lipid mediators in innate immunity against tuberculosis: opposing roles of PGE2 and LXA4 in the induction of macrophage death. J Exp Med. 2008 Nov 24; 205(12):2791-801.
    View in: PubMed
  5. Gan H, Lee J, Ren F, Chen M, Kornfeld H, Remold HG. Mycobacterium tuberculosis blocks crosslinking of annexin-1 and apoptotic envelope formation on infected macrophages to maintain virulence. Nat Immunol. 2008 Oct; 9(10):1189-97.
    View in: PubMed
  6. Chen M, Gan H, Remold HG. A mechanism of virulence: virulent Mycobacterium tuberculosis strain H37Rv, but not attenuated H37Ra, causes significant mitochondrial inner membrane disruption in macrophages leading to necrosis. J Immunol. 2006 Mar 15; 176(6):3707-16.
    View in: PubMed
  7. Gan H, He X, Duan L, Mirabile-Levens E, Kornfeld H, Remold HG. Enhancement of antimycobacterial activity of macrophages by stabilization of inner mitochondrial membrane potential. J Infect Dis. 2005 Apr 15; 191(8):1292-300.
    View in: PubMed
  8. Duan L, Gan H, Golan DE, Remold HG. Critical role of mitochondrial damage in determining outcome of macrophage infection with Mycobacterium tuberculosis. J Immunol. 2002 Nov 1; 169(9):5181-7.
    View in: PubMed
  9. Newman GW, Gan HX, McCarthy PL, Remold HG. Survival of human macrophages infected with Mycobacterium avium intracellulare correlates with increased production of tumor necrosis factor-alpha and IL-6. J Immunol. 1991 Dec 1; 147(11):3942-8.
    View in: PubMed
  10. Gan HX, Ruef C, Hall BF, Tobin E, Remold HG, Mellors JW. Interleukin-6 expression in primary macrophages infected with human immunodeficiency virus-1 (HIV-1). AIDS Res Hum Retroviruses. 1991 Aug; 7(8):671-9.
    View in: PubMed
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