Seth Rakoff-Nahoum, M.D.
| Title | Clinical Fellow in Pediatrics (EXT) |
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| Institution | Children's Hospital Boston |
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| Department | Pediatrics |
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| Address | Children's Hospital House Staff Lounge Pavilion Lobby 300 Longwood Ave Boston MA 02115
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| Phone | 617/355-6369 |
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Mentoring Available: 07/01/11, Expires: 07/01/14 The human intestine harbors trillions of microbes and is one of the most complex ecosystems on the planet. We know very little about these microbes, predominantly bacteria, let alone the interactions that these bacteria with each other and the host that they inhabit. Your project would be to apply ecologic and evolutionary theory, especially that of social evolution, with the tools of bacterial genetics to better understand this environment which is increasingly emerging as critical to human health. Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Rakoff-Nahoum S, Bousvaros A. Innate and adaptive immune connections in inflammatory bowel diseases. Curr Opin Gastroenterol. 2010 Nov; 26(6):572-7.
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Rakoff-Nahoum S, Medzhitov R. Toll-like receptors and cancer. Nat Rev Cancer. 2009 Jan; 9(1):57-63.
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Rakoff-Nahoum S, Medzhitov R. Innate immune recognition of the indigenous microbial flora. Mucosal Immunol. 2008 Nov; 1 Suppl 1:S10-4.
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Rakoff-Nahoum S, Medzhitov R. Role of toll-like receptors in tissue repair and tumorigenesis. Biochemistry (Mosc). 2008 May; 73(5):555-61.
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Garrison KE, Jones RB, Meiklejohn DA, Anwar N, Ndhlovu LC, Chapman JM, Erickson AL, Agrawal A, Spotts G, Hecht FM, Rakoff-Nahoum S, Lenz J, Ostrowski MA, Nixon DF. T cell responses to human endogenous retroviruses in HIV-1 infection. PLoS Pathog. 2007 Nov; 3(11):e165.
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Rakoff-Nahoum S, Medzhitov R. Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88. Science. 2007 Jul 6; 317(5834):124-7.
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Rakoff-Nahoum S, Medzhitov R. Prostaglandin-secreting cells: a portable first aid kit for tissue repair. J Clin Invest. 2007 Jan; 117(1):83-6.
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Rakoff-Nahoum S. Why cancer and inflammation? Yale J Biol Med. 2006 Dec; 79(3-4):123-30.
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Rakoff-Nahoum S, Chen H, Kraus T, George I, Oei E, Tyorkin M, Salik E, Beuria P, Sperber K. Retraction: Regulation of class II expression in monocytic cells after HIV-1 infection. J Immunol. 2006 Nov 1; 177(9):6561.
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Rakoff-Nahoum S, Hao L, Medzhitov R. Role of toll-like receptors in spontaneous commensal-dependent colitis. Immunity. 2006 Aug; 25(2):319-29.
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Rakoff-Nahoum S, Kuebler PJ, Heymann JJ, E Sheehy M, Ortiz GM, S Ogg G, Barbour JD, Lenz J, Steinfeld AD, Nixon DF. Detection of T lymphocytes specific for human endogenous retrovirus K (HERV-K) in patients with seminoma. AIDS Res Hum Retroviruses. 2006 Jan; 22(1):52-6.
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Rakoff-Nahoum S, Medzhitov R. Role of the innate immune system and host-commensal mutualism. Curr Top Microbiol Immunol. 2006; 308:1-18.
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Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, Edberg S, Medzhitov R. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell. 2004 Jul 23; 118(2):229-41.
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Rakoff-Nahoum S, Chen H, Kraus T, George I, Oei E, Tyorkin M, Salik E, Beuria P, Sperber K. Regulation of class II expression in monocytic cells after HIV-1 infection. J Immunol. 2001 Aug 15; 167(4):2331-42.
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