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Seth Rakoff-Nahoum, M.D.

TitleClinical Fellow in Pediatrics (EXT)
InstitutionChildren's Hospital Boston
DepartmentPediatrics
AddressChildren's Hospital
House Staff Lounge Pavilion Lobby
300 Longwood Ave
Boston MA 02115
Phone617/355-6369

 Mentoring 
 current student opportunities
Available: 07/01/11, Expires: 07/01/14

The human intestine harbors trillions of microbes and is one of the most complex ecosystems on the planet. We know very little about these microbes, predominantly bacteria, let alone the interactions that these bacteria with each other and the host that they inhabit. Your project would be to apply ecologic and evolutionary theory, especially that of social evolution, with the tools of bacterial genetics to better understand this environment which is increasingly emerging as critical to human health.


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Rakoff-Nahoum S, Bousvaros A. Innate and adaptive immune connections in inflammatory bowel diseases. Curr Opin Gastroenterol. 2010 Nov; 26(6):572-7.
    View in: PubMed
  2. Rakoff-Nahoum S, Medzhitov R. Toll-like receptors and cancer. Nat Rev Cancer. 2009 Jan; 9(1):57-63.
    View in: PubMed
  3. Rakoff-Nahoum S, Medzhitov R. Innate immune recognition of the indigenous microbial flora. Mucosal Immunol. 2008 Nov; 1 Suppl 1:S10-4.
    View in: PubMed
  4. Rakoff-Nahoum S, Medzhitov R. Role of toll-like receptors in tissue repair and tumorigenesis. Biochemistry (Mosc). 2008 May; 73(5):555-61.
    View in: PubMed
  5. Garrison KE, Jones RB, Meiklejohn DA, Anwar N, Ndhlovu LC, Chapman JM, Erickson AL, Agrawal A, Spotts G, Hecht FM, Rakoff-Nahoum S, Lenz J, Ostrowski MA, Nixon DF. T cell responses to human endogenous retroviruses in HIV-1 infection. PLoS Pathog. 2007 Nov; 3(11):e165.
    View in: PubMed
  6. Rakoff-Nahoum S, Medzhitov R. Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88. Science. 2007 Jul 6; 317(5834):124-7.
    View in: PubMed
  7. Rakoff-Nahoum S, Medzhitov R. Prostaglandin-secreting cells: a portable first aid kit for tissue repair. J Clin Invest. 2007 Jan; 117(1):83-6.
    View in: PubMed
  8. Rakoff-Nahoum S. Why cancer and inflammation? Yale J Biol Med. 2006 Dec; 79(3-4):123-30.
    View in: PubMed
  9. Rakoff-Nahoum S, Chen H, Kraus T, George I, Oei E, Tyorkin M, Salik E, Beuria P, Sperber K. Retraction: Regulation of class II expression in monocytic cells after HIV-1 infection. J Immunol. 2006 Nov 1; 177(9):6561.
    View in: PubMed
  10. Rakoff-Nahoum S, Hao L, Medzhitov R. Role of toll-like receptors in spontaneous commensal-dependent colitis. Immunity. 2006 Aug; 25(2):319-29.
    View in: PubMed
  11. Rakoff-Nahoum S, Kuebler PJ, Heymann JJ, E Sheehy M, Ortiz GM, S Ogg G, Barbour JD, Lenz J, Steinfeld AD, Nixon DF. Detection of T lymphocytes specific for human endogenous retrovirus K (HERV-K) in patients with seminoma. AIDS Res Hum Retroviruses. 2006 Jan; 22(1):52-6.
    View in: PubMed
  12. Rakoff-Nahoum S, Medzhitov R. Role of the innate immune system and host-commensal mutualism. Curr Top Microbiol Immunol. 2006; 308:1-18.
    View in: PubMed
  13. Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, Edberg S, Medzhitov R. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell. 2004 Jul 23; 118(2):229-41.
    View in: PubMed
  14. Rakoff-Nahoum S, Chen H, Kraus T, George I, Oei E, Tyorkin M, Salik E, Beuria P, Sperber K. Regulation of class II expression in monocytic cells after HIV-1 infection. J Immunol. 2001 Aug 15; 167(4):2331-42.
    View in: PubMed
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