Ali Khademhosseini, PH.D.
| Title | Associate Professor of Medicine |
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| Institution | Brigham and Women's Hospital |
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| Department | Medicine |
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| Address | Partners Research Building BWH/ Rm 265 65 Landsdowne St Cambridge MA 02139
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| Phone | 617/768-8395 |
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| Title | Associate Professor of Health Sciences and Technology |
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| Institution | Massachusetts Institute of Technology |
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| Department | Health Sciences and Technology |
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Mentoring A Microwell Platform for Interrogating Embryoid Body Differentiation Summer, 06/04/07 - 08/10/07 Epicardial extracellular matrix environment specifies cell fate Summer, 06/20/10 - 08/14/10 Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
Faculty can login to make corrections and additions.
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Selimovic S, Dokmeci MR, Khademhosseini A. Research highlights. Lab Chip. 2013 Apr 2; 13(9):1662-5.
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Camci-Unal G, Cuttica D, Annabi N, Demarchi D, Khademhosseini A. Synthesis and characterization of hybrid hyaluronic Acid-gelatin hydrogels. Biomacromolecules. 2013 Apr 8; 14(4):1085-92.
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Almodóvar J, Crouzier T, Selimovic S, Boudou T, Khademhosseini A, Picart C. Gradients of physical and biochemical cues on polyelectrolyte multilayer films generated via microfluidics. Lab Chip. 2013 Mar 19; 13(8):1562-70.
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Selimovic S, Tibbitt MW, Dokmeci MR, Khademhosseini A. Research highlights. Lab Chip. 2013 Mar 19; 13(8):1453-6.
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Patel A, Gaharwar AK, Iviglia G, Zhang H, Mukundan S, Mihaila SM, Demarchi D, Khademhosseini A. Highly elastomeric poly(glycerol sebacate)-co-poly(ethylene glycol) amphiphilic block copolymers. Biomaterials. 2013 May; 34(16):3970-83.
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Shin SR, Jung SM, Zalabany M, Kim K, Zorlutuna P, Kim SB, Nikkhah M, Khabiry M, Azize M, Kong J, Wan KT, Palacios T, Dokmeci MR, Bae H, Tang XS, Khademhosseini A. Carbon-nanotube-embedded hydrogel sheets for engineering cardiac constructs and bioactuators. ACS Nano. 2013 Mar 26; 7(3):2369-80.
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Ahadian S, Ramón-Azcón J, Ostrovidov S, Camci-Unal G, Kaji H, Ino K, Shiku H, Khademhosseini A, Matsue T. A contactless electrical stimulator: application to fabricate functional skeletal muscle tissue. Biomed Microdevices. 2013 Feb; 15(1):109-15.
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Khademhosseini A, Peppas NA. Micro- and nanoengineering of biomaterials for healthcare applications. Adv Healthc Mater. 2013 Jan; 2(1):10-2.
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Selimovic S, Dokmeci MR, Khademhosseini A. Research highlights. Lab Chip. 2012 Dec 21; 12(24):5127-9.
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Naahidi S, Jafari M, Edalat F, Raymond K, Khademhosseini A, Chen P. Biocompatibility of engineered nanoparticles for drug delivery. J Control Release. 2013 Mar 10; 166(2):182-94.
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Zorlutuna P, Vrana NE, Khademhosseini A. The expanding world of tissue engineering: the building blocks and new applications of tissue engineered constructs. IEEE Rev Biomed Eng. 2013; 6:47-62.
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Selimovic S, Dokmeci MR, Annabi N, Khademhosseini A. Research highlights. Lab Chip. 2013 Jan 21; 13(2):193-5.
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Khademhosseini A. Interview: interview with ali khademhosseini. Ther Deliv. 2012 Dec; 3(12):1379-81.
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Hosseini V, Ahadian S, Ostrovidov S, Camci-Unal G, Chen S, Kaji H, Ramalingam M, Khademhosseini A. Engineered contractile skeletal muscle tissue on a microgrooved methacrylated gelatin substrate. Tissue Eng Part A. 2012 Dec; 18(23-24):2453-65.
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Bauer M, Kang L, Qiu Y, Wu J, Peng M, Chen HH, Camci-Unal G, Bayomy AF, Sosnovik DE, Khademhosseini A, Liao R. Adult cardiac progenitor cell aggregates exhibit survival benefit both in vitro and in vivo. PLoS One. 2012; 7(11):e50491.
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Schukur L, Zorlutuna P, Cha JM, Bae H, Khademhosseini A. Directed Differentiation of Size-Controlled Embryoid Bodies Towards Endothelial and Cardiac Lineages in RGD-Modified Poly(Ethylene Glycol) Hydrogels. Adv Healthc Mater. 2013 Jan; 2(1):195-205.
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Selimovic S, Camci-Unal G, Dokmeci MR, Khademhosseini A. Research highlights. Lab Chip. 2013 Jan 7; 13(1):14-6.
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Sant S, Iyer D, Gaharwar AK, Patel A, Khademhosseini A. Effect of biodegradation and de novo matrix synthesis on the mechanical properties of valvular interstitial cell-seeded polyglycerol sebacate-polycaprolactone scaffolds. Acta Biomater. 2013 Apr; 9(4):5963-73.
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Bae H, Puranik AS, Gauvin R, Edalat F, Carrillo-Conde B, Peppas NA, Khademhosseini A. Building vascular networks. Sci Transl Med. 2012 Nov 14; 4(160):160ps23.
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Cha C, Liechty WB, Khademhosseini A, Peppas NA. Designing biomaterials to direct stem cell fate. ACS Nano. 2012 Nov 27; 6(11):9353-8.
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Tekin H, Sanchez JG, Landeros C, Dubbin K, Langer R, Khademhosseini A. Tissue Engineering: Controlling Spatial Organization of Multiple Cell Types in Defined 3D Geometries (Adv. Mater. 41/2012). Adv Mater. 2012 Nov 2; 24(41):5542.
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Camci-Unal G, Memic A, Hasan MA, Dokmeci MR, Khademhosseini A. Research highlights. Lab Chip. 2012 Oct 30; 12(23):4943-5.
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Kim SB, Koo KI, Bae H, Dokmeci MR, Hamilton GA, Bahinski A, Kim SM, Ingber DE, Khademhosseini A. A mini-microscope for in situ monitoring of cells. Lab Chip. 2012 Oct 21; 12(20):3976-82.
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Selimovic S, Dokmeci MR, Khademhosseini A. Research highlights. Lab Chip. 2012 Oct 16; 12(22):4665-6.
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Park SH, Sim WY, Min BH, Yang SS, Khademhosseini A, Kaplan DL. Chip-based comparison of the osteogenesis of human bone marrow- and adipose tissue-derived mesenchymal stem cells under mechanical stimulation. PLoS One. 2012; 7(9):e46689.
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Nikkhah M, Eshak N, Zorlutuna P, Annabi N, Castello M, Kim K, Dolatshahi-Pirouz A, Edalat F, Bae H, Yang Y, Khademhosseini A. Directed endothelial cell morphogenesis in micropatterned gelatin methacrylate hydrogels. Biomaterials. 2012 Dec; 33(35):9009-18.
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Nguyen LH, Annabi N, Nikkhah M, Bae H, Binan L, Park S, Kang Y, Yang Y, Khademhosseini A. Vascularized bone tissue engineering: approaches for potential improvement. Tissue Eng Part B Rev. 2012 Oct; 18(5):363-82.
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Tekin H, Sanchez JG, Landeros C, Dubbin K, Langer R, Khademhosseini A. Controlling Spatial Organization of Multiple Cell Types in Defined 3D Geometries. Adv Mater. 2012 Nov 2; 24(41):5543-7.
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Coutinho DF, Ahari AF, Kachouie NN, Gomes ME, Neves NM, Reis RL, Khademhosseini A. An automated two-phase system for hydrogel microbead production. Biofabrication. 2012 Sep; 4(3):035003.
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Deforest CA, Zhang H, Memic A, Dokmeci M, Khademhosseini A. Research highlights. Lab Chip. 2012 Aug 20; 12(19):3540-2.
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Kang Y, Kim S, Fahrenholtz M, Khademhosseini A, Yang Y. Osteogenic and angiogenic potentials of monocultured and co-cultured human-bone-marrow-derived mesenchymal stem cells and human-umbilical-vein endothelial cells on three-dimensional porous beta-tricalcium phosphate scaffold. Acta Biomater. 2013 Jan; 9(1):4906-15.
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Patel B, Gauvin R, Absar S, Gupta V, Gupta N, Nahar K, Khademhosseini A, Ahsan F. Computational and bioengineered lungs as alternatives to whole animal, isolated organ, and cell-based lung models. Am J Physiol Lung Cell Mol Physiol. 2012 Nov 1; 303(9):L733-47.
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Selimovic S, Saedinia S, Dokmeci MR, Khademhosseini A. Research highlights. Lab Chip. 2012 Sep 21; 12(18):3217-20.
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Bauer M, Kim K, Qiu Y, Calpe B, Khademhosseini A, Liao R, Wheeldon I. Spot identification and quality control in cell-based microarrays. ACS Comb Sci. 2012 Aug 13; 14(8):471-7.
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Ahadian S, Ramón-Azcón J, Ostrovidov S, Camci-Unal G, Hosseini V, Kaji H, Ino K, Shiku H, Khademhosseini A, Matsue T. Interdigitated array of Pt electrodes for electrical stimulation and engineering of aligned muscle tissue. Lab Chip. 2012 Sep 21; 12(18):3491-503.
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Kim J, Hwang YS, Chung AM, Chung BG, Khademhosseini A. Liver cell line derived conditioned medium enhances myofibril organization of primary rat cardiomyocytes. Mol Cells. 2012 Aug; 34(2):149-58.
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Selimovic S, Deforest CA, Dokmeci MR, Khademhosseini A. Research highlights. Lab Chip. 2012 Sep 7; 12(17):2995-7.
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Kang Y, Kim S, Bishop J, Khademhosseini A, Yang Y. The osteogenic differentiation of human bone marrow MSCs on HUVEC-derived ECM and ß-TCP scaffold. Biomaterials. 2012 Oct; 33(29):6998-7007.
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Ramón-Azcón J, Ahadian S, Obregón R, Camci-Unal G, Ostrovidov S, Hosseini V, Kaji H, Ino K, Shiku H, Khademhosseini A, Matsue T. Gelatin methacrylate as a promising hydrogel for 3D microscale organization and proliferation of dielectrophoretically patterned cells. Lab Chip. 2012 Aug 21; 12(16):2959-69.
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Selimovic S, Camci-Unal G, Dokmeci MR, Khademhosseini A. Research highlights. Lab Chip. 2012 Jun 28.
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Edalat F, Sheu I, Manoucheri S, Khademhosseini A. Material strategies for creating artificial cell-instructive niches. Curr Opin Biotechnol. 2012 Oct; 23(5):820-5.
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Selimovic S, Dokmeci MR, Khademhosseini A. Research highlights. Lab Chip. 2012 Jul 21; 12(14):2435-7.
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Selimovic S, Deforest CA, Dokmeci MR, Khademhosseini A. Research highlights. Lab Chip. 2012 Jun 6; 12(13):2289-91.
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Ahmed M, Yildirimer L, Khademhosseini A, Seifalian AM. Nanostructured materials for cardiovascular tissue engineering. J Nanosci Nanotechnol. 2012 Jun; 12(6):4775-85.
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Selimovic S, Deforest CA, Dokmeci MR, Khademhosseini A. Research highlights. Lab Chip. 2012 Jun 21; 12(12):2094-6.
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Selimovic S, Deforest CA, Dokmeci MR, Khademhosseini A. Research highlights. Lab Chip. 2012 May 8; 12(11):2015-7.
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Nikkhah M, Edalat F, Manoucheri S, Khademhosseini A. Engineering microscale topographies to control the cell-substrate interface. Biomaterials. 2012 Jul; 33(21):5230-46.
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Selimovic Š, Dokmeci MR, Khademhosseini A. Research highlights. Lab Chip. 2012 Apr 21; 12(8):1409-11.
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Zorlutuna P, Annabi N, Camci-Unal G, Nikkhah M, Cha JM, Nichol JW, Manbachi A, Bae H, Chen S, Khademhosseini A. Microfabricated biomaterials for engineering 3D tissues. Adv Mater. 2012 Apr 10; 24(14):1782-804.
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Kim BC, Bae H, Kwon IK, Lee EJ, Park JH, Khademhosseini A, Hwang YS. Osteoblastic/Cementoblastic and neural differentiation of dental stem cells and their applications to tissue engineering and regenerative medicine. Tissue Eng Part B Rev. 2012 Jun; 18(3):235-44.
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Gauvin R, Chen YC, Lee JW, Soman P, Zorlutuna P, Nichol JW, Bae H, Chen S, Khademhosseini A. Microfabrication of complex porous tissue engineering scaffolds using 3D projection stereolithography. Biomaterials. 2012 May; 33(15):3824-34.
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Kim SB, Bae H, Koo KI, Dokmeci MR, Ozcan A, Khademhosseini A. Lens-free imaging for biological applications. J Lab Autom. 2012 Feb; 17(1):43-9.
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Shin H, Olsen BD, Khademhosseini A. The mechanical properties and cytotoxicity of cell-laden double-network hydrogels based on photocrosslinkable gelatin and gellan gum biomacromolecules. Biomaterials. 2012 Apr; 33(11):3143-52.
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Ostrovidov S, Annabi N, Seidi A, Ramalingam M, Dehghani F, Kaji H, Khademhosseini A. Controlled release of drugs from gradient hydrogels for high-throughput analysis of cell-drug interactions. Anal Chem. 2012 Feb 7; 84(3):1302-9.
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Shin SR, Bae H, Cha JM, Mun JY, Chen YC, Tekin H, Shin H, Farshchi S, Dokmeci MR, Tang S, Khademhosseini A. Carbon nanotube reinforced hybrid microgels as scaffold materials for cell encapsulation. ACS Nano. 2012 Jan 24; 6(1):362-72.
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Piraino F, Camci-Unal G, Hancock MJ, Rasponi M, Khademhosseini A. Multi-gradient hydrogels produced layer by layer with capillary flow and crosslinking in open microchannels. Lab Chip. 2012 Feb 7; 12(3):659-61.
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Hancock MJ, Yanagawa F, Jang YH, He J, Kachouie NN, Kaji H, Khademhosseini A. Designer hydrophilic regions regulate droplet shape for controlled surface patterning and 3D microgel synthesis. Small. 2012 Feb 6; 8(3):393-403.
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Gauvin R, Parenteau-Bareil R, Dokmeci MR, Merryman WD, Khademhosseini A. Hydrogels and microtechnologies for engineering the cellular microenvironment. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2012 May-Jun; 4(3):235-46.
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Sant S, Tao SL, Fisher OZ, Xu Q, Peppas NA, Khademhosseini A. Microfabrication technologies for oral drug delivery. Adv Drug Deliv Rev. 2012 May 1; 64(6):496-507.
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Chung BG, Lee KH, Khademhosseini A, Lee SH. Microfluidic fabrication of microengineered hydrogels and their application in tissue engineering. Lab Chip. 2012 Jan 7; 12(1):45-59.
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Edalat F, Bae H, Manoucheri S, Cha JM, Khademhosseini A. Engineering approaches toward deconstructing and controlling the stem cell environment. Ann Biomed Eng. 2012 Jun; 40(6):1301-15.
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Ghaemmaghami AM, Hancock MJ, Harrington H, Kaji H, Khademhosseini A. Biomimetic tissues on a chip for drug discovery. Drug Discov Today. 2012 Feb; 17(3-4):173-81.
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Bashir R, Khademhosseini A, Sia S. Delving into BioMEMS. IEEE Pulse. 2011 Nov; 2(6):12.
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Gauvin R, Guillemette M, Dokmeci M, Khademhosseini A. Application of microtechnologies for the vascularization of engineered tissues. Vasc Cell. 2011; 3:24.
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Selimovic S, Khademhosseini A. Research highlights. Lab Chip. 2011 Nov 7; 11(21):3581-3.
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Selimovic S, Khademhosseini A. Research highlights. Lab Chip. 2011 Oct 21; 11(20):3386-8.
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Ji C, Khademhosseini A, Dehghani F. Enhancing cell penetration and proliferation in chitosan hydrogels for tissue engineering applications. Biomaterials. 2011 Dec; 32(36):9719-29.
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Kang E, Jeong GS, Choi YY, Lee KH, Khademhosseini A, Lee SH. Digitally tunable physicochemical coding of material composition and topography in continuous microfibres. Nat Mater. 2011 Nov; 10(11):877-83.
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Hancock MJ, Piraino F, Camci-Unal G, Rasponi M, Khademhosseini A. Anisotropic material synthesis by capillary flow in a fluid stripe. Biomaterials. 2011 Sep; 32(27):6493-504.
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Khademhosseini A, Bornscheuer UT. Engineering of pathways, cells and tissues. Curr Opin Biotechnol. 2011 Oct; 22(5):601-3.
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Jang YH, Hancock MJ, Kim SB, Selimovic Š, Sim WY, Bae H, Khademhosseini A. An integrated microfluidic device for two-dimensional combinatorial dilution. Lab Chip. 2011 Oct 7; 11(19):3277-86.
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Tekin H. Bioanalysis young investigator: Halil Tekin. Interview by Ali Khademhosseini and Robert S Langer. Bioanalysis. 2011 Aug; 3(16):1815-6.
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Tekin H, Tsinman T, Sanchez JG, Jones BJ, Camci-Unal G, Nichol JW, Langer R, Khademhosseini A. Responsive micromolds for sequential patterning of hydrogel microstructures. J Am Chem Soc. 2011 Aug 24; 133(33):12944-7.
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Tong Z, Sant S, Khademhosseini A, Jia X. Controlling the fibroblastic differentiation of mesenchymal stem cells via the combination of fibrous scaffolds and connective tissue growth factor. Tissue Eng Part A. 2011 Nov; 17(21-22):2773-85.
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Sadr N, Zhu M, Osaki T, Kakegawa T, Yang Y, Moretti M, Fukuda J, Khademhosseini A. SAM-based cell transfer to photopatterned hydrogels for microengineering vascular-like structures. Biomaterials. 2011 Oct; 32(30):7479-90.
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Selimovic Š, Khademhosseini A. Research highlights. Cell beads for building macroscopic tissues. Lab Chip. 2011 Aug 21; 11(16):2651-2.
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Sewell-Loftin MK, Chun YW, Khademhosseini A, Merryman WD. EMT-inducing biomaterials for heart valve engineering: taking cues from developmental biology. J Cardiovasc Transl Res. 2011 Oct; 4(5):658-71.
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Brooks D, Brown EN, Casler R, Fantini S, Khademhosseini A, Niemi J, Ramachandran R, Rutkove S, Tracey B. Boston research takes center stage. Interview by Pamela Reynolds. IEEE Pulse. 2011 Jul-Aug; 2(4):31-8.
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Seidi A, Kaji H, Annabi N, Ostrovidov S, Ramalingam M, Khademhosseini A. A microfluidic-based neurotoxin concentration gradient for the generation of an in vitro model of Parkinson's disease. Biomicrofluidics. 2011 Jun; 5(2):22214.
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Dokmeci MR, Khademhosseini A. Preface to Special Topic: Microfluidics in cell biology and tissue engineering. Biomicrofluidics. 2011 Jun; 5(2):22101.
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Gauvin R, Khademhosseini A. Microscale technologies and modular approaches for tissue engineering: moving toward the fabrication of complex functional structures. ACS Nano. 2011 Jun 28; 5(6):4258-64.
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Kang Y, Kim S, Khademhosseini A, Yang Y. Creation of bony microenvironment with CaP and cell-derived ECM to enhance human bone-marrow MSC behavior and delivery of BMP-2. Biomaterials. 2011 Sep; 32(26):6119-30.
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Selimovic S, Piraino F, Bae H, Rasponi M, Redaelli A, Khademhosseini A. Microfabricated polyester conical microwells for cell culture applications. Lab Chip. 2011 Jul 21; 11(14):2325-32.
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Yamanlar S, Sant S, Boudou T, Picart C, Khademhosseini A. Surface functionalization of hyaluronic acid hydrogels by polyelectrolyte multilayer films. Biomaterials. 2011 Aug; 32(24):5590-9.
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Kwon CH, Wheeldon I, Kachouie NN, Lee SH, Bae H, Sant S, Fukuda J, Kang JW, Khademhosseini A. Drug-eluting microarrays for cell-based screening of chemical-induced apoptosis. Anal Chem. 2011 Jun 1; 83(11):4118-25.
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Hutson CB, Nichol JW, Aubin H, Bae H, Yamanlar S, Al-Haque S, Koshy ST, Khademhosseini A. Synthesis and characterization of tunable poly(ethylene glycol): gelatin methacrylate composite hydrogels. Tissue Eng Part A. 2011 Jul; 17(13-14):1713-23.
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Kim SB, Bae H, Cha JM, Moon SJ, Dokmeci MR, Cropek DM, Khademhosseini A. A cell-based biosensor for real-time detection of cardiotoxicity using lensfree imaging. Lab Chip. 2011 May 21; 11(10):1801-7.
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Sant S, Hwang CM, Lee SH, Khademhosseini A. Hybrid PGS-PCL microfibrous scaffolds with improved mechanical and biological properties. J Tissue Eng Regen Med. 2011 Apr; 5(4):283-91.
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Wheeldon I, Farhadi A, Bick AG, Jabbari E, Khademhosseini A. Nanoscale tissue engineering: spatial control over cell-materials interactions. Nanotechnology. 2011 May 27; 22(21):212001.
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Tekin H, Ozaydin-Ince G, Tsinman T, Gleason KK, Langer R, Khademhosseini A, Demirel MC. Responsive microgrooves for the formation of harvestable tissue constructs. Langmuir. 2011 May 3; 27(9):5671-9.
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Du Y, Ghodousi M, Qi H, Haas N, Xiao W, Khademhosseini A. Sequential assembly of cell-laden hydrogel constructs to engineer vascular-like microchannels. Biotechnol Bioeng. 2011 Jul; 108(7):1693-703.
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Hancock MJ, He J, Mano JF, Khademhosseini A. Surface-tension-driven gradient generation in a fluid stripe for bench-top and microwell applications. Small. 2011 Apr 4; 7(7):892-901.
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Selimovic Š, Sim WY, Kim SB, Jang YH, Lee WG, Khabiry M, Bae H, Jambovane S, Hong JW, Khademhosseini A. Generating nonlinear concentration gradients in microfluidic devices for cell studies. Anal Chem. 2011 Mar 15; 83(6):2020-8.
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Xiao W, He J, Nichol JW, Wang L, Hutson CB, Wang B, Du Y, Fan H, Khademhosseini A. Synthesis and characterization of photocrosslinkable gelatin and silk fibroin interpenetrating polymer network hydrogels. Acta Biomater. 2011 Jun; 7(6):2384-93.
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Jang YH, Kwon CH, Kim SB, Selimovic S, Sim WY, Bae H, Khademhosseini A. Deep wells integrated with microfluidic valves for stable docking and storage of cells. Biotechnol J. 2011 Feb; 6(2):156-64.
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Seidi A, Ramalingam M, Elloumi-Hannachi I, Ostrovidov S, Khademhosseini A. Gradient biomaterials for soft-to-hard interface tissue engineering. Acta Biomater. 2011 Apr; 7(4):1441-51.
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Soliman S, Sant S, Nichol JW, Khabiry M, Traversa E, Khademhosseini A. Controlling the porosity of fibrous scaffolds by modulating the fiber diameter and packing density. J Biomed Mater Res A. 2011 Mar 1; 96(3):566-74.
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He J, Du Y, Guo Y, Hancock MJ, Wang B, Shin H, Wu J, Li D, Khademhosseini A. Microfluidic synthesis of composite cross-gradient materials for investigating cell-biomaterial interactions. Biotechnol Bioeng. 2011 Jan; 108(1):175-85.
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Spelke DP, Ortmann D, Khademhosseini A, Ferreira L, Karp JM. Methods for embryoid body formation: the microwell approach. Methods Mol Biol. 2011; 690:151-62.
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Qi H, Du Y, Wang L, Kaji H, Bae H, Khademhosseini A. Patterned differentiation of individual embryoid bodies in spatially organized 3D hybrid microgels. Adv Mater. 2010 Dec 7; 22(46):5276-81.
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Ji C, Annabi N, Khademhosseini A, Dehghani F. Fabrication of porous chitosan scaffolds for soft tissue engineering using dense gas CO2. Acta Biomater. 2011 Apr; 7(4):1653-64.
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Mokashi SA, Guan J, Wang D, Tchantchaleishvili V, Brigham M, Lipsitz S, Lee LS, Schmitto JD, Bolman RM, Khademhosseini A, Liao R, Chen FY. Preventing cardiac remodeling: the combination of cell-based therapy and cardiac support therapy preserves left ventricular function in rodent model of myocardial ischemia. J Thorac Cardiovasc Surg. 2010 Dec; 140(6):1374-80.
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Kachouie NN, Fieguth P, Gamble D, Jervis E, Ezziane Z, Khademhosseini A. Constrained watershed method to infer morphology of mammalian cells in microscopic images. Cytometry A. 2010 Dec; 77(12):1148-59.
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Wu J, Wheeldon I, Guo Y, Lu T, Du Y, Wang B, He J, Hu Y, Khademhosseini A. A sandwiched microarray platform for benchtop cell-based high throughput screening. Biomaterials. 2011 Jan; 32(3):841-8.
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Kachouie NN, Du Y, Bae H, Khabiry M, Ahari AF, Zamanian B, Fukuda J, Khademhosseini A. Directed assembly of cell-laden hydrogels for engineering functional tissues. Organogenesis. 2010 Oct-Dec; 6(4):234-44.
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Coutinho DF, Sant SV, Shin H, Oliveira JT, Gomes ME, Neves NM, Khademhosseini A, Reis RL. Modified Gellan Gum hydrogels with tunable physical and mechanical properties. Biomaterials. 2010 Oct; 31(29):7494-502.
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Hwang CM, Sim WY, Lee SH, Foudeh AM, Bae H, Lee SH, Khademhosseini A. Benchtop fabrication of PDMS microstructures by an unconventional photolithographic method. Biofabrication. 2010 Dec; 2(4):045001.
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Hwang CM, Sant S, Masaeli M, Kachouie NN, Zamanian B, Lee SH, Khademhosseini A. Fabrication of three-dimensional porous cell-laden hydrogel for tissue engineering. Biofabrication. 2010 Sep; 2(3):035003.
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Basu A, Cheung KC, Eddington DT, Günther A, Hansen C, Huang TJ, Juncker D, Kaji H, Khademhosseini A, Khan SA, Klapperich C, Love JC, Munson M, Murthy S, Ozcan A, Ozinsky A, Spotts JM, Squires T, Takeuchi S, Wang W, Williams J. Contributors to the emerging investigators issue. Lab Chip. 2010 Sep 21; 10(18):2323-33.
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Cioffi M, Moretti M, Manbachi A, Chung BG, Khademhosseini A, Dubini G. A computational and experimental study inside microfluidic systems: the role of shear stress and flow recirculation in cell docking. Biomed Microdevices. 2010 Aug; 12(4):619-26.
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Annabi N, Nichol JW, Zhong X, Ji C, Koshy S, Khademhosseini A, Dehghani F. Controlling the porosity and microarchitecture of hydrogels for tissue engineering. Tissue Eng Part B Rev. 2010 Aug; 16(4):371-83.
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Tekin H, Anaya M, Brigham MD, Nauman C, Langer R, Khademhosseini A. Stimuli-responsive microwells for formation and retrieval of cell aggregates. Lab Chip. 2010 Sep 21; 10(18):2411-8.
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Kaji H, Camci-Unal G, Langer R, Khademhosseini A. Engineering systems for the generation of patterned co-cultures for controlling cell-cell interactions. Biochim Biophys Acta. 2011 Mar; 1810(3):239-50.
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Shin H, Nichol JW, Khademhosseini A. Cell-adhesive and mechanically tunable glucose-based biodegradable hydrogels. Acta Biomater. 2011 Jan; 7(1):106-14.
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Okuyama T, Yamazoe H, Mochizuki N, Khademhosseini A, Suzuki H, Fukuda J. Preparation of arrays of cell spheroids and spheroid-monolayer cocultures within a microfluidic device. J Biosci Bioeng. 2010 Nov; 110(5):572-6.
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Fernandez JG, Khademhosseini A. Micro-masonry: construction of 3D structures by microscale self-assembly. Adv Mater. 2010 Jun 18; 22(23):2538-41.
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Kang L, Hancock MJ, Brigham MD, Khademhosseini A. Cell confinement in patterned nanoliter droplets in a microwell array by wiping. J Biomed Mater Res A. 2010 May; 93(2):547-57.
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Park JH, Chung BG, Lee WG, Kim J, Brigham MD, Shim J, Lee S, Hwang CM, Durmus NG, Demirci U, Khademhosseini A. Microporous cell-laden hydrogels for engineered tissue constructs. Biotechnol Bioeng. 2010 May 1; 106(1):138-48.
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Nichol JW, Koshy ST, Bae H, Hwang CM, Yamanlar S, Khademhosseini A. Cell-laden microengineered gelatin methacrylate hydrogels. Biomaterials. 2010 Jul; 31(21):5536-44.
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Zamanian B, Masaeli M, Nichol JW, Khabiry M, Hancock MJ, Bae H, Khademhosseini A. Interface-directed self-assembly of cell-laden microgels. Small. 2010 Apr 23; 6(8):937-44.
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Lee WG, Ortmann D, Hancock MJ, Bae H, Khademhosseini A. A hollow sphere soft lithography approach for long-term hanging drop methods. Tissue Eng Part C Methods. 2010 Apr; 16(2):249-59.
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Fisher OZ, Khademhosseini A, Langer R, Peppas NA. Bioinspired materials for controlling stem cell fate. Acc Chem Res. 2010 Mar 16; 43(3):419-28.
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Choi YY, Chung BG, Lee DH, Khademhosseini A, Kim JH, Lee SH. Controlled-size embryoid body formation in concave microwell arrays. Biomaterials. 2010 May; 31(15):4296-303.
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Du Y, Ghodousi M, Lo E, Vidula MK, Emiroglu O, Khademhosseini A. Surface-directed assembly of cell-laden microgels. Biotechnol Bioeng. 2010 Feb 15; 105(3):655-62.
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Moon S, Hasan SK, Song YS, Xu F, Keles HO, Manzur F, Mikkilineni S, Hong JW, Nagatomi J, Haeggstrom E, Khademhosseini A, Demirci U. Layer by layer three-dimensional tissue epitaxy by cell-laden hydrogel droplets. Tissue Eng Part C Methods. 2010 Feb; 16(1):157-66.
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Sant S, Khademhosseini A. Fabrication and characterization of tough elastomeric fibrous scaffolds for tissue engineering applications. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:3546-8.
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Du Y, Hancock MJ, He J, Villa-Uribe JL, Wang B, Cropek DM, Khademhosseini A. Convection-driven generation of long-range material gradients. Biomaterials. 2010 Mar; 31(9):2686-94.
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Shi Z, Chen N, Du Y, Khademhosseini A, Alber M. Stochastic model of self-assembly of cell-laden hydrogels. Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Dec; 80(6 Pt 1):061901.
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Murtuza B, Nichol JW, Khademhosseini A. Micro- and nanoscale control of the cardiac stem cell niche for tissue fabrication. Tissue Eng Part B Rev. 2009 Dec; 15(4):443-54.
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Lee WG, Kim YG, Chung BG, Demirci U, Khademhosseini A. Nano/Microfluidics for diagnosis of infectious diseases in developing countries. Adv Drug Deliv Rev. 2010 Mar 18; 62(4-5):449-57.
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Charnley M, Textor M, Khademhosseini A, Lutolf MP. Integration column: microwell arrays for mammalian cell culture. Integr Biol (Camb). 2009 Dec; 1(11-12):625-34.
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Jeong HE, Kwak R, Khademhosseini A, Suh KY. UV-assisted capillary force lithography for engineering biomimetic multiscale hierarchical structures: From lotus leaf to gecko foot hairs. Nanoscale. 2009 Dec; 1(3):331-8.
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Hwang YS, Chung BG, Ortmann D, Hattori N, Moeller HC, Khademhosseini A. Microwell-mediated control of embryoid body size regulates embryonic stem cell fate via differential expression of WNT5a and WNT11. Proc Natl Acad Sci U S A. 2009 Oct 6; 106(40):16978-83.
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Slaughter BV, Khurshid SS, Fisher OZ, Khademhosseini A, Peppas NA. Hydrogels in regenerative medicine. Adv Mater. 2009 Sep 4; 21(32-33):3307-29.
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Kachouie N, Kang L, Khademhosseini A. Arraycount, an algorithm for automatic cell counting in microwell arrays. Biotechniques. 2009 Sep; 47(3):x-xvi.
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Hwang CM, Park Y, Park JY, Lee K, Sun K, Khademhosseini A, Lee SH. Controlled cellular orientation on PLGA microfibers with defined diameters. Biomed Microdevices. 2009 Aug; 11(4):739-46.
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Song YS, Lin RL, Montesano G, Durmus NG, Lee G, Yoo SS, Kayaalp E, Haeggström E, Khademhosseini A, Demirci U. Engineered 3D tissue models for cell-laden microfluidic channels. Anal Bioanal Chem. 2009 Sep; 395(1):185-93.
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Brigham MD, Bick A, Lo E, Bendali A, Burdick JA, Khademhosseini A. Mechanically robust and bioadhesive collagen and photocrosslinkable hyaluronic acid semi-interpenetrating networks. Tissue Eng Part A. 2009 Jul; 15(7):1645-53.
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Hacking SA, Khademhosseini A. Applications of microscale technologies for regenerative dentistry. J Dent Res. 2009 May; 88(5):409-21.
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Khabiry M, Chung BG, Hancock MJ, Soundararajan HC, Du Y, Cropek D, Lee WG, Khademhosseini A. Cell docking in double grooves in a microfluidic channel. Small. 2009 May; 5(10):1186-94.
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Khademhosseini A, Vacanti JP, Langer R. Progress in tissue engineering. Sci Am. 2009 May; 300(5):64-71.
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Inaba R, Khademhosseini A, Suzuki H, Fukuda J. Electrochemical desorption of self-assembled monolayers for engineering cellular tissues. Biomaterials. 2009 Jul; 30(21):3573-9.
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Moon S, Keles HO, Ozcan A, Khademhosseini A, Haeggstrom E, Kuritzkes D, Demirci U. Integrating microfluidics and lensless imaging for point-of-care testing. Biosens Bioelectron. 2009 Jul 15; 24(11):3208-14.
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Lee WG, Demirci U, Khademhosseini A. Microscale electroporation: challenges and perspectives for clinical applications. Integr Biol (Camb). 2009 Mar; 1(3):242-51.
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Hacking SA, Kachouie NN, Lee WG, Khademhosseini A. Future approaches to organ regeneration: microscale environments, stem cell engineering, and self-assembly of living tissues. Stud Health Technol Inform. 2009; 149:214-35.
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Du Y, Shim J, Vidula M, Hancock MJ, Lo E, Chung BG, Borenstein JT, Khabiry M, Cropek DM, Khademhosseini A. Rapid generation of spatially and temporally controllable long-range concentration gradients in a microfluidic device. Lab Chip. 2009 Mar 21; 9(6):761-7.
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Du Y, Lo E, Ali S, Khademhosseini A. Directed assembly of cell-laden microgels for fabrication of 3D tissue constructs. Proc Natl Acad Sci U S A. 2008 Jul 15; 105(28):9522-7.
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Jinno S, Moeller HC, Chen CL, Rajalingam B, Chung BG, Dokmeci MR, Khademhosseini A. Microfabricated multilayer parylene-C stencils for the generation of patterned dynamic co-cultures. J Biomed Mater Res A. 2008 Jul; 86(1):278-88.
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Hwang CM, Khademhosseini A, Park Y, Sun K, Lee SH. Microfluidic chip-based fabrication of PLGA microfiber scaffolds for tissue engineering. Langmuir. 2008 Jun 1; 24(13):6845-51.
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Panda P, Ali S, Lo E, Chung BG, Hatton TA, Khademhosseini A, Doyle PS. Stop-flow lithography to generate cell-laden microgel particles. Lab Chip. 2008 Jul; 8(7):1056-61.
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Wright D, Rajalingam B, Karp JM, Selvarasah S, Ling Y, Yeh J, Langer R, Dokmeci MR, Khademhosseini A. Reusable, reversibly sealable parylene membranes for cell and protein patterning. J Biomed Mater Res A. 2008 May; 85(2):530-8.
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Manbachi A, Shrivastava S, Cioffi M, Chung BG, Moretti M, Demirci U, Yliperttula M, Khademhosseini A. Microcirculation within grooved substrates regulates cell positioning and cell docking inside microfluidic channels. Lab Chip. 2008 May; 8(5):747-54.
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Hosseinkhani H, Hosseinkhani M, Gabrielson NP, Pack DW, Khademhosseini A, Kobayashi H. DNA nanoparticles encapsulated in 3D tissue-engineered scaffolds enhance osteogenic differentiation of mesenchymal stem cells. J Biomed Mater Res A. 2008 Apr; 85(1):47-60.
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Tian F, Hosseinkhani H, Hosseinkhani M, Khademhosseini A, Yokoyama Y, Estrada GG, Kobayashi H. Quantitative analysis of cell adhesion on aligned micro- and nanofibers. J Biomed Mater Res A. 2008 Feb; 84(2):291-9.
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Teply BA, Tong R, Jeong SY, Luther G, Sherifi I, Yim CH, Khademhosseini A, Farokhzad OC, Langer RS, Cheng J. The use of charge-coupled polymeric microparticles and micromagnets for modulating the bioavailability of orally delivered macromolecules. Biomaterials. 2008 Mar; 29(9):1216-23.
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Chung BG, Kang L, Khademhosseini A. Micro- and nanoscale technologies for tissue engineering and drug discovery applications. Expert Opin Drug Discov. 2007 Dec; 2(12):1653-68.
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Kang L, Chung BG, Langer R, Khademhosseini A. Microfluidics for drug discovery and development: from target selection to product lifecycle management. Drug Discov Today. 2008 Jan; 13(1-2):1-13.
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Moeller HC, Mian MK, Shrivastava S, Chung BG, Khademhosseini A. A microwell array system for stem cell culture. Biomaterials. 2008 Feb; 29(6):752-63.
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Hong S, Lee D, Zhang H, Zhang JQ, Resvick JN, Khademhosseini A, King MR, Langer R, Karp JM. Covalent immobilization of p-selectin enhances cell rolling. Langmuir. 2007 Nov 20; 23(24):12261-8.
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Chang TY, Yadav VG, De Leo S, Mohedas A, Rajalingam B, Chen CL, Selvarasah S, Dokmeci MR, Khademhosseini A. Cell and protein compatibility of parylene-C surfaces. Langmuir. 2007 Nov 6; 23(23):11718-25.
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Chung BG, Manbachi A, Saadi W, Lin F, Jeon NL, Khademhosseini A. A gradient-generating microfluidic device for cell biology. J Vis Exp. 2007; (7):271.
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Khademhosseini A. Experimental approaches to tissue engineering. J Vis Exp. 2007; (7):272.
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Chung BG, Manbachi A, Khademhosseini A. A microfluidic device with groove patterns for studying cellular behavior. J Vis Exp. 2007; (7):270.
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Khademhosseini A, Langer R. Microengineered hydrogels for tissue engineering. Biomaterials. 2007 Dec; 28(34):5087-92.
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Wright D, Rajalingam B, Selvarasah S, Dokmeci MR, Khademhosseini A. Generation of static and dynamic patterned co-cultures using microfabricated parylene-C stencils. Lab Chip. 2007 Oct; 7(10):1272-9.
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Ling Y, Rubin J, Deng Y, Huang C, Demirci U, Karp JM, Khademhosseini A. A cell-laden microfluidic hydrogel. Lab Chip. 2007 Jun; 7(6):756-62.
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Karp JM, Yeh J, Eng G, Fukuda J, Blumling J, Suh KY, Cheng J, Mahdavi A, Borenstein J, Langer R, Khademhosseini A. Controlling size, shape and homogeneity of embryoid bodies using poly(ethylene glycol) microwells. Lab Chip. 2007 Jun; 7(6):786-94.
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Khademhosseini A, Eng G, Yeh J, Kucharczyk PA, Langer R, Vunjak-Novakovic G, Radisic M. Microfluidic patterning for fabrication of contractile cardiac organoids. Biomed Microdevices. 2007 Apr; 9(2):149-57.
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Khademhosseini A, Eng G, Yeh J, Fukuda J, Blumling J, Langer R, Burdick JA. Micromolding of photocrosslinkable hyaluronic acid for cell encapsulation and entrapment. J Biomed Mater Res A. 2006 Dec 1; 79(3):522-32.
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Hosseinkhani M, Hosseinkhani H, Khademhosseini A, Bolland F, Kobayashi H, Gonzalez SP. Bone morphogenetic protein-4 enhances cardiomyocyte differentiation of cynomolgus monkey ESCs in knockout serum replacement medium. Stem Cells. 2007 Mar; 25(3):571-80.
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Franzesi GT, Ni B, Ling Y, Khademhosseini A. A controlled-release strategy for the generation of cross-linked hydrogel microstructures. J Am Chem Soc. 2006 Nov 29; 128(47):15064-5.
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Hosseinkhani H, Hosseinkhani M, Khademhosseini A, Kobayashi H. Bone regeneration through controlled release of bone morphogenetic protein-2 from 3-D tissue engineered nano-scaffold. J Control Release. 2007 Feb 26; 117(3):380-6.
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Kim P, Jeong HE, Khademhosseini A, Suh KY. Fabrication of non-biofouling polyethylene glycol micro- and nanochannels by ultraviolet-assisted irreversible sealing. Lab Chip. 2006 Nov; 6(11):1432-7.
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Farokhzad OC, Dimitrakov JD, Karp JM, Khademhosseini A, Freeman MR, Langer R. Drug delivery systems in urology--getting "smarter". Urology. 2006 Sep; 68(3):463-9.
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Hosseinkhani H, Hosseinkhani M, Khademhosseini A, Kobayashi H, Tabata Y. Enhanced angiogenesis through controlled release of basic fibroblast growth factor from peptide amphiphile for tissue regeneration. Biomaterials. 2006 Dec; 27(34):5836-44.
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Khademhosseini A, Ferreira L, Blumling J, Yeh J, Karp JM, Fukuda J, Langer R. Co-culture of human embryonic stem cells with murine embryonic fibroblasts on microwell-patterned substrates. Biomaterials. 2006 Dec; 27(36):5968-77.
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Yeh J, Ling Y, Karp JM, Gantz J, Chandawarkar A, Eng G, Blumling J, Langer R, Khademhosseini A. Micromolding of shape-controlled, harvestable cell-laden hydrogels. Biomaterials. 2006 Nov; 27(31):5391-8.
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Fukuda J, Khademhosseini A, Yeo Y, Yang X, Yeh J, Eng G, Blumling J, Wang CF, Kohane DS, Langer R. Micromolding of photocrosslinkable chitosan hydrogel for spheroid microarray and co-cultures. Biomaterials. 2006 Oct; 27(30):5259-67.
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Suh KY, Khademhosseini A, Jon S, Langer R. Direct confinement of individual viruses within polyethylene glycol (PEG) nanowells. Nano Lett. 2006 Jun; 6(6):1196-201.
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Khademhosseini A, Langer R, Borenstein J, Vacanti JP. Microscale technologies for tissue engineering and biology. Proc Natl Acad Sci U S A. 2006 Feb 21; 103(8):2480-7.
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Cheng J, Teply BA, Jeong SY, Yim CH, Ho D, Sherifi I, Jon S, Farokhzad OC, Khademhosseini A, Langer RS. Magnetically responsive polymeric microparticles for oral delivery of protein drugs. Pharm Res. 2006 Mar; 23(3):557-64.
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Khademhosseini A, Bettinger C, Karp JM, Yeh J, Ling Y, Borenstein J, Fukuda J, Langer R. Interplay of biomaterials and micro-scale technologies for advancing biomedical applications. J Biomater Sci Polym Ed. 2006; 17(11):1221-40.
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Khademhosseini A. Chips to Hits: microarray and microfluidic technologies for high-throughput analysis and drug discovery. September 12-15, 2005, MA, USA. Expert Rev Mol Diagn. 2005 Nov; 5(6):843-6.
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Khademhosseini A, May MH, Sefton MV. Conformal coating of mammalian cells immobilized onto magnetically driven beads. Tissue Eng. 2005 Nov-Dec; 11(11-12):1797-806.
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Karp JM, Ferreira LS, Khademhosseini A, Kwon AH, Yeh J, Langer RS. Cultivation of human embryonic stem cells without the embryoid body step enhances osteogenesis in vitro. Stem Cells. 2006 Apr; 24(4):835-43.
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Fukuda J, Khademhosseini A, Yeh J, Eng G, Cheng J, Farokhzad OC, Langer R. Micropatterned cell co-cultures using layer-by-layer deposition of extracellular matrix components. Biomaterials. 2006 Mar; 27(8):1479-86.
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Khademhosseini A, Yeh J, Eng G, Karp J, Kaji H, Borenstein J, Farokhzad OC, Langer R. Cell docking inside microwells within reversibly sealed microfluidic channels for fabricating multiphenotype cell arrays. Lab Chip. 2005 Dec; 5(12):1380-6.
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Kim P, Kim DH, Kim B, Choi SK, Lee SH, Khademhosseini A, Langer R, Suh KY. Fabrication of nanostructures of polyethylene glycol for applications to protein adsorption and cell adhesion. Nanotechnology. 2005 Oct; 16(10):2420-6.
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Farokhzad OC, Khademhosseini A, Jon S, Hermmann A, Cheng J, Chin C, Kiselyuk A, Teply B, Eng G, Langer R. Microfluidic system for studying the interaction of nanoparticles and microparticles with cells. Anal Chem. 2005 Sep 1; 77(17):5453-9.
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Suh KY, Yang JM, Khademhosseini A, Berry D, Tran TN, Park H, Langer R. Characterization of chemisorbed hyaluronic acid directly immobilized on solid substrates. J Biomed Mater Res B Appl Biomater. 2005 Feb 15; 72(2):292-8.
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Farokhzad OC, Jon S, Khademhosseini A, Tran TN, Lavan DA, Langer R. Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells. Cancer Res. 2004 Nov 1; 64(21):7668-72.
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Suh KY, Khademhosseini A, Yoo PJ, Langer R. Patterning and separating infected bacteria using host-parasite and virus-antibody interactions. Biomed Microdevices. 2004 Sep; 6(3):223-9.
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Khademhosseini A, Suh KY, Yang JM, Eng G, Yeh J, Levenberg S, Langer R. Layer-by-layer deposition of hyaluronic acid and poly-L-lysine for patterned cell co-cultures. Biomaterials. 2004 Aug; 25(17):3583-92.
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Khademhosseini A, Yeh J, Jon S, Eng G, Suh KY, Burdick JA, Langer R. Molded polyethylene glycol microstructures for capturing cells within microfluidic channels. Lab Chip. 2004 Oct; 4(5):425-30.
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Suh KY, Khademhosseini A, Eng G, Langer R. Single nanocrystal arrays on patterned poly(ethylene glycol) copolymer microstructures using selective wetting and drying. Langmuir. 2004 Jul 20; 20(15):6080-4.
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Khademhosseini A, Suh KY, Jon S, Eng G, Yeh J, Chen GJ, Langer R. A soft lithographic approach to fabricate patterned microfluidic channels. Anal Chem. 2004 Jul 1; 76(13):3675-81.
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Burdick JA, Khademhosseini A, Langer R. Fabrication of gradient hydrogels using a microfluidics/photopolymerization process. Langmuir. 2004 Jun 22; 20(13):5153-6.
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Suh KY, Seong J, Khademhosseini A, Laibinis PE, Langer R. A simple soft lithographic route to fabrication of poly(ethylene glycol) microstructures for protein and cell patterning. Biomaterials. 2004 Feb; 25(3):557-63.
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