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John Warren Harthorne, M.D.,C.M.

TitleProfessor of Medicine
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
Internal Medicine
55 Fruit St
Boston MA 02114
Phone617/726-2876
Fax617/726-5988

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Singh JP, Heist EK, Ruskin JN, Harthorne JW. "Dialing-in" cardiac resynchronization therapy: overcoming constraints of the coronary venous anatomy. J Interv Card Electrophysiol. 2006 Oct; 17(1):51-8.
    View in: PubMed
  2. Harthorne JW. Seymour Furman. Pacing Clin Electrophysiol. 2006 May; 29(5):450.
    View in: PubMed
  3. Harthorne JW. Seymour Furman, M.D. 7-12-1931 - 2-20-2006. Heart Rhythm. 2006 Apr; 3(4):498-9.
    View in: PubMed
  4. Heist EK, Harthorne JW, Singh JP. Pacing for atrioventricular block. N Engl J Med. 2005 Oct 20; 353(16):1742-4; author reply 1742-4.
    View in: PubMed
  5. Harthorne JW, Palacios I. Medical mystery--the answer. N Engl J Med. 2002 Aug 1; 347(5):371.
    View in: PubMed
  6. Suri R, Harthorne JW, Galvin J. Automatically optimizing pacing output: an excellent idea, but with potentially lethal pitfalls. Pacing Clin Electrophysiol. 2001 Apr; 24(4 Pt 1):520-3.
    View in: PubMed
  7. Harthorne JW. Pacemakers and store security devices. Cardiol Rev. 2001 Jan-Feb; 9(1):10-7.
    View in: PubMed
  8. Harthorne JW. Effects of physiologic pacing versus ventricular pacing. N Engl J Med. 2000 Nov 9; 343(19):1417-8; discussion 1418.
    View in: PubMed
  9. Harthorne JW. Implantable defibrillators, pacemakers, and electronic antitheft devices. N Engl J Med. 1999 Apr 8; 340(14):1117; author reply 1118-9.
    View in: PubMed
  10. Harthorne JW. Sagging body parts. Pacing Clin Electrophysiol. 1999 Feb; 22(2):375.
    View in: PubMed
  11. Harthorne JW. Theft deterrent systems: a threat for medical device recipients or an industry cat fight? Pacing Clin Electrophysiol. 1998 Oct; 21(10):1845-6.
    View in: PubMed
  12. Kam RM, Garan H, McGovern BA, Ruskin JN, Harthorne JW. Transient right bundle branch block causing R wave attenuation postdefibrillation. Pacing Clin Electrophysiol. 1997 Jan; 20(1 Pt 1):130-1.
    View in: PubMed
  13. Roelke M, O'Nunain SS, Osswald S, Garan H, Harthorne JW, Ruskin JN. Subclavian crush syndrome complicating transvenous cardioverter defibrillator systems. Pacing Clin Electrophysiol. 1995 May; 18(5 Pt 1):973-9.
    View in: PubMed
  14. Roelke M, O'Nunain S, Osswald S, Trouton TG, Harthorne JW, Garan H, Ruskin JN. Ventricular pacing induced ventricular tachycardia in patients with implantable cardioverter defibrillators. Pacing Clin Electrophysiol. 1995 Mar; 18(3 Pt 1):486-91.
    View in: PubMed
  15. Roelke M, Jackson G, Harthorne JW. Submammary pacemaker implantation: a unique tunneling technique. Pacing Clin Electrophysiol. 1994 Nov; 17(11 Pt 1):1793-6.
    View in: PubMed
  16. Roelke M, McNamara D, Osswald S, Semigran M, Dec W, Harthorne JW. A comparison of VVIR and DDDR pacing following cardiac transplantation. Pacing Clin Electrophysiol. 1994 Nov; 17(11 Pt 2):2047-51.
    View in: PubMed
  17. Furman S, Parsonnet V, Goldman BS, Denes P, Song SL, Maloney JD, Harthorne JW, Griffin JC. Performance of implantable cardiac rhythm management devices. Pacing Clin Electrophysiol. 1989 Mar; 12(3):510-8.
    View in: PubMed
  18. Kelly PA, Cannom DS, Garan H, Mirabal GS, Harthorne JW, Hurvitz RJ, Vlahakes GJ, Jacobs ML, Ilvento JP, Buckley MJ, et al. The automatic implantable cardioverter-defibrillator: efficacy, complications and survival in patients with malignant ventricular arrhythmias. J Am Coll Cardiol. 1988 Jun; 11(6):1278-86.
    View in: PubMed
  19. Bilitch M, Denes P, Goldman BS, Maloney JD, Harthorne JW, Griffin JC, Furman S, Parsonnet V. Performance of implantable cardiac rhythm management devices. Pacing Clin Electrophysiol. 1988 Mar; 11(3):371-80.
    View in: PubMed
  20. Rediker DE, Eagle KA, Homma S, Gillam LD, Harthorne JW. Clinical and hemodynamic comparison of VVI versus DDD pacing in patients with DDD pacemakers. Am J Cardiol. 1988 Feb 1; 61(4):323-9.
    View in: PubMed
  21. Harthorne JW. Cardiac pacemakers. Curr Probl Cardiol. 1987 Nov; 12(11):649-93.
    View in: PubMed
  22. Bilitch M, Hauser RG, Goldman BS, Maloney JD, Harthorne JW, Furman S, Parsonnet V. Performance of implantable cardiac rhythm management devices. Pacing Clin Electrophysiol. 1987 Mar; 10(2):389-98.
    View in: PubMed
  23. Eagle KA, Mulley AG, Singer DE, Schoenfeld D, Harthorne JW, Thibault GE. Single-chamber and dual-chamber cardiac pacemakers. A formal cost comparison. Ann Intern Med. 1986 Aug; 105(2):264-71.
    View in: PubMed
  24. Harthorne JW, Parsonnet V. 17th Bethesda conference: Adult cardiology training. Task Force VI: Training in cardiac pacing. J Am Coll Cardiol. 1986 Jun; 7(6):1213-4.
    View in: PubMed
  25. Harthorne JW, Eisenhauer AC, Steinhaus DM. Pacemaker-mediated tachycardias: an unresolved problem. Pacing Clin Electrophysiol. 1984 Nov; 7(6 Pt 2):1140-7.
    View in: PubMed
  26. Harthorne JW. Pacemaker leads. Int J Cardiol. 1984 Oct; 6(4):423-9.
    View in: PubMed
  27. Stewart WJ, Dicola VC, Harthorne JW, Gillam LD, Weyman AE. Doppler ultrasound measurement of cardiac output in patients with physiologic pacemakers. Effects of left ventricular function and retrograde ventriculoatrial conduction. Am J Cardiol. 1984 Aug 1; 54(3):308-12.
    View in: PubMed
  28. Parsonnet V, Escher DJ, Furman S, Gillette PC, Goldman BS, Harthorne JW, Hauser RG, Levine PA, Maloney J. Indications for dual-chamber pacing. Pacing Clin Electrophysiol. 1984 May; 7(3 Pt 1):318-9.
    View in: PubMed
  29. DiCola VC, Harthorne JW. Physiological pacemakers. Annu Rev Med. 1984; 35:493-502.
    View in: PubMed
  30. Boucher CA, Pohost GM, Okada RD, Levine FH, Strauss HW, Harthorne JW. Effect of ventricular pacing on left ventricular function assessed by radionuclide angiography. Am Heart J. 1983 Nov; 106(5 Pt 1):1105-11.
    View in: PubMed
  31. Harthorne JW, Dicola V. Infrequent cause of erratic pacemaker performance. Pacing Clin Electrophysiol. 1983 May; 6(3 Pt 1):655-6.
    View in: PubMed
  32. Harthorne JW. Programmable pacemakers: technical features and clinical applications. Cardiovasc Clin. 1983; 14(2):135-47.
    View in: PubMed
  33. McEnany MT, Salzman EW, Mundth ED, DeSanctis RW, Harthorne JW, Weintraub RM, Gates S, Austen WG. The effect of antithrombotic therapy on patency rates of saphenous vein coronary artery bypass grafts. J Thorac Cardiovasc Surg. 1982 Jan; 83(1):81-9.
    View in: PubMed
  34. DiMarco JP, Garan H, Harthorne JW, Ruskin JN. Intracardiac electrophysiologic techniques in recurrent syncope of unknown case. Ann Intern Med. 1981 Nov; 95(5):542-8.
    View in: PubMed
  35. Harthorne JW. Indications for pacemaker insertion: types and modes of pacing. Prog Cardiovasc Dis. 1981 May-Jun; 23(6):393-400.
    View in: PubMed
  36. Harthorne JW. Historic milestones of electrotherapy and cardiac pacing. Prog Cardiovasc Dis. 1981 May-Jun; 23(6):389-92.
    View in: PubMed
  37. Harthorne JW. Attempted suicide by self-removal of implanted pacemaker. Pacing Clin Electrophysiol. 1980 Nov; 3(6):740-1.
    View in: PubMed
  38. Ruskin JN, Garan H, Poulin F, Harthorne JW. Permanent radiofrequency ventricular pacing for management of drug-resistant ventricular tachycardia. Am J Cardiol. 1980 Aug; 46(2):317-21.
    View in: PubMed
  39. Harthorne JW, Furman S. In the People's Republic of China. Pacing Clin Electrophysiol. 1980 May; 3(3):253-6.
    View in: PubMed
  40. Poulin FK, Harthorne JW. The cardiac pacemaker: functions, falterings, and fate. Geriatrics. 1980 Apr; 35(4):87-100.
    View in: PubMed
  41. Zir LM, Dinsmore R, Vexeridis M, Singh JB, Harthorne JW, Daggett WM. Effects of coronary bypass grafting on resting left ventricular contraction in patients studied 1 to 2 years after operation. Am J Cardiol. 1979 Oct; 44(4):601-6.
    View in: PubMed
  42. Harthorne JW. North American Society of Pacing and Electrophysiology (NASPE). Pacing Clin Electrophysiol. 1979 Sep; 2(5):521-2.
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  43. Dodinot B, Harthorne JW, Kormann DS, Parsonnet V. Professional qualifications for pacemaker implantation. Pacing Clin Electrophysiol. 1978 Jul; 1(3):361-6.
    View in: PubMed
  44. Dash H, Johnson RA, Dinsmore RE, Francis CK, Harthorne JW. Cardiomyopathic syndrome due to coronary arter disease. II: Increased prevalence in patients with diabetes mellitus: a matched pair analysis. Br Heart J. 1977 Jul; 39(7):740-7.
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  45. Dash H, Johnson RA, Dinsmore RE, Harthorne JW. Cardiomyopathic syndrome due to coronary artery disease. I: Relation to angiographic extent of coronary disease and to remote myocardial infarction. Br Heart J. 1977 Jul; 39(7):733-9.
    View in: PubMed
  46. Zir LM, Miller SW, Dinsmore RE, Gilbert JP, Harthorne JW. Interobserver variability in coronary angiography. Circulation. 1976 Apr; 53(4):627-32.
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  47. Caulfield JB, Zir L, Harthorne JW. Blood calcium levels in the presence of arteriographic contrast material. Circulation. 1975 Jul; 52(1):119-23.
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  48. Shubrooks SJ, Zir LM, Dinsmore RE, Harthorne JW. Left ventricular wall motion response to intravenous propranolol. Circulation. 1975 Jul; 52(1):124-9.
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  49. Rubenstein JJ, Pohost GM, Dinsmore RE, Harthorne JW. The echocardiographic determination of mitral valve opening and closure. Correlation with hemodynamic studies in man. Circulation. 1975 Jan; 51(1):98-103.
    View in: PubMed
  50. Zir LM, Dinsmore RE, Goss C, Harthorne JW. Experience with preformed catheters for coronary angiography by the brachial approach. Cathet Cardiovasc Diagn. 1975; 1(3):303-10.
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  51. Zir LM, DeSanctis RW, Harthorne JW. Diagnostic uses of electrical pacing. Cardiovasc Clin. 1975; 6(3):401-14.
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  52. Leberthson RR, Dinsmore RE, Bharati S, Rubenstein JJ, Caulfield J, Wheeler EO, Harthorne JW, Lev M. Aberrant coronary artery origin from the aorta. Diagnosis and clinical significance. Circulation. 1974 Oct; 50(4):774-9.
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  53. Johnson RA, Hutter AM, Desanctis RW, Yurchak PM, Leinbach RC, Harthorne JW. Chronic overdrive pacing in the control of refractory ventricular arrhythmias. Ann Intern Med. 1974 Mar; 80(3):380-3.
    View in: PubMed
  54. Liberthson RR, Barron K, Harthorne JW, Dinsmore RE, Daggett WM. Traumatic coronary arterial fistula. A case report and review of the literature. Am Heart J. 1973 Dec; 86(6):817-21.
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  55. Armstrong PW, Dinsmore RE, Harthorne JW, Sanders CA. Hemodynamic clues to the discrepancy between the angiographic and intraoperative assessment of aortic regurgitation. J Thorac Cardiovasc Surg. 1973 Aug; 66(2):265-70.
    View in: PubMed
  56. Mundth ED, Harthorne JW, Buckley MJ, Dinsmore R, Austen WG. Direct coronary arterial revascularization. Treatment of cardiac failure associated with coronary artery disease. Arch Surg. 1971 Nov; 103(5):529-34.
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  57. Mundth ED, Harthorne JW, Buckley MJ, Daggett WM, Austen WG. Direct coronary artery surgery for coronary artery occlusive disease. Am J Surg. 1971 Apr; 121(4):478-84.
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  58. Smith RF, Jackson DH, Harthorne JW, Sanders CA. Acquired bundle branch block in a healthy population. Am Heart J. 1970 Dec; 80(6):746-51.
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  59. Mundth ED, Harthorne JW, Buckley MJ, Dinsmore RE, Austen WG. Direct coronary arterial revascularization for segmental occlusive disease. Surgery. 1970 Jan; 67(1):168-81.
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  60. Harthorne JW, Dinsmore RE, Desanctis RW. Superior vena caval anomaly preventing pervenous pacemaker implantation. Br Heart J. 1969 Nov; 31(6):809-10.
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  61. Harthorne JW, Leinbach RC, Sanders CA, Austen WG. Clinical results of transvenous pacing. Ann N Y Acad Sci. 1969 Oct 30; 167(2):1008-15.
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  62. Kastor JA, DeSctis RW, Leinbach RC, Harthorne JW, Wolfson IN. Long-term pervenous atrial pacing. Circulation. 1969 Oct; 40(4):535-44.
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  63. Leinbach RC, Chamberlain DA, Kastor JA, Harthorne JW, Sanders CA. A comparison of the hemodynamic effects of ventricular and sequential A-V pacing in patients with heart block. Am Heart J. 1969 Oct; 78(4):502-8.
    View in: PubMed
  64. Kastor JA, Sanders CA, Leinbach RC, Harthorne JW. Factors influencing retrograde conduction. Study of 30 patients during cardiac catheterization. Br Heart J. 1969 Sep; 31(5):580-7.
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  65. Robboy SJ, Harthorne JW, Leinbach RC, Sanders CA, Austen WG. Autopsy findings with permanent pervenous pacemakers. Circulation. 1969 Apr; 39(4):495-501.
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  66. Harthorne JW, DeSanctis RW, Sulit YQ, Sanders CA, Austen WG. Epicardial versus endocardial pacemakers. Analysis of 109 cases. Ann Thorac Surg. 1968 Nov; 6(5):417-23.
    View in: PubMed
  67. Leinbach RC, Harthorne JW, Dinsmore RE. Straight back syndrome with pulmonary venous osbtruction. Am J Cardiol. 1968 Apr; 21(4):588-92.
    View in: PubMed
  68. Harthorne JW. Anticoagulants and valve replacement during pregnancy. Ann Intern Med. 1968 Feb; 68(2):495.
    View in: PubMed
  69. Harthorne JW, Buckley MJ, Grover JW, Austen WG. Valve replacement during pregnancy. Ann Intern Med. 1967 Nov; 67(5):1032-4.
    View in: PubMed
  70. Kumar S, Harthorne JW, Dinsmore RE, Sanders CA. Opacification of the right heart complicating left ventricular angiography. Am J Cardiol. 1967 Jul; 20(1):133-5.
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  71. Smith RF, Harthorne JW, Sanders CA. Vectorcardiographic changes during intracoronary injections. Circulation. 1967 Jul; 36(1):63-76.
    View in: PubMed
  72. Shine KI, O'Keefe D, Harthorne JW. Arteriovenous fistula after retrograde brachial catheterization. N Engl J Med. 1967 Jun 22; 276(25):1431.
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  73. Seltzer RA, Harthorne JW, Austen WG. The appearance and significance of left atrial calcification. Am J Roentgenol Radium Ther Nucl Med. 1967 Jun; 100(2):307-11.
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  74. Kastor JA, DeSanctis RW, Harthorne JW, Schwartz GH. Transvenous atrial pacing in the treatment of refractory ventricular irritability. Ann Intern Med. 1967 May; 66(5):939-45.
    View in: PubMed
  75. Harthorne JW, Austen WG, Corning H, McNamara JJ, Sanders CA. Permanent endocardial pacing in complete heart block. Assessment of the technique and the advantages in 20 patients. Ann Intern Med. 1967 May; 66(5):831-7.
    View in: PubMed
  76. Sanders CA, Austen WG, Harthorne JW, Dinsmore RE, Scannell JG. Diagnosis and surgical treatment of mitral regurgitation secondary to ruptured chordae tendineae. N Engl J Med. 1967 Apr 27; 276(17):943-9.
    View in: PubMed
  77. Harthorne JW, Kantrowitz PA, Dinsmore RE, Sanders CA. Traumatic myocardial infarction. Report of a case with normal coronary angiogram. Ann Intern Med. 1967 Feb; 66(2):341-4.
    View in: PubMed
  78. Dinsmore RE, Sanders CA, Harthorne JW. Mitral regurgitation in idiopathic hypertrophic subaortic stenosis. N Engl J Med. 1966 Dec 1; 275(22):1225-8.
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  79. Dinsmore RE, Rourke JA, DeSanctis RD, Harthorne JW, Austen WG. Angiographic findings in dissecting aortic aneurysm. N Engl J Med. 1966 Nov 24; 275(21):1152-7.
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  80. Harthorne JW, Scannell JG, Dinsmore RE. Anomalous origin of the left coronary artery. Remediable cause of sudden death in adults. N Engl J Med. 1966 Sep 22; 275(12):660-3.
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  81. Dinsmore RE, Sanders CA, Harthorne JW, Austen WG. Congenital pulmonary stenosis with calcification. Radiology. 1966 Sep; 87(3):429-35.
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  82. Harthorne JW, Seltzer RA, Austen WG. Left atrial calcification. Review of literature and proposed management. Circulation. 1966 Aug; 34(2):198-210.
    View in: PubMed
  83. Sanders CA, Harthorne JW, DeSanctis RW, Austen WE. Tricuspid stenosis, a difficult diagnosis in the presence of atrial fibrillation. Circulation. 1966 Jan; 33(1):26-33.
    View in: PubMed
  84. SANDERS CA, SCANNELL JG, HARTHORNE JW, AUSTEN WG. SEVERE MITRAL REGURGITATION SECONDARY TO RUPTURED CHORDAE TENDINEAE. Circulation. 1965 Apr; 31:506-16.
    View in: PubMed
  85. HARTHORNE JW, MARCUS AM, KAYE M. Management of massive imipramine overdosage with mannitol and artificial dialysis. N Engl J Med. 1963 Jan 3; 268:33-6.
    View in: PubMed
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