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Sava Sakadzic, PH.D.

TitleInstructor in Radiology
InstitutionMassachusetts General Hospital
DepartmentRadiology
AddressMassachusetts General Hospital
Radiology, Rm. 2301
149 13th Street
Charlestown MA 02129

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Nizar K, Uhlirova H, Tian P, Saisan PA, Cheng Q, Reznichenko L, Weldy KL, Steed TC, Sridhar VB, Macdonald CL, Cui J, Gratiy SL, Sakadzic S, Boas DA, Beka TI, Einevoll GT, Chen J, Masliah E, Dale AM, Silva GA, Devor A. In vivo Stimulus-Induced Vasodilation Occurs without IP3 Receptor Activation and May Precede Astrocytic Calcium Increase. J Neurosci. 2013 May 8; 33(19):8411-8422.
    View in: PubMed
  2. Yaseen MA, Sakadžic S, Wu W, Becker W, Kasischke KA, Boas DA. In vivo imaging of cerebral energy metabolism with two-photon fluorescence lifetime microscopy of NADH. Biomed Opt Express. 2013 Feb 1; 4(2):307-21.
    View in: PubMed
  3. Esipova TV, Ye X, Collins JE, Sakadzic S, Mandeville ET, Murray CB, Vinogradov SA. Dendritic upconverting nanoparticles enable in vivo multiphoton microscopy with low-power continuous wave sources. Proc Natl Acad Sci U S A. 2012 Dec 18; 109(51):20826-31.
    View in: PubMed
  4. Goergen CJ, Radhakrishnan H, Sakadžic S, Mandeville ET, Lo EH, Sosnovik DE, Srinivasan VJ. Optical coherence tractography using intrinsic contrast. Opt Lett. 2012 Sep 15; 37(18):3882-4.
    View in: PubMed
  5. Devor A, Sakadžic S, Srinivasan VJ, Yaseen MA, Nizar K, Saisan PA, Tian P, Dale AM, Vinogradov SA, Franceschini MA, Boas DA. Frontiers in optical imaging of cerebral blood flow and metabolism. J Cereb Blood Flow Metab. 2012 Jul; 32(7):1259-76.
    View in: PubMed
  6. Yuzawa I, Sakadžic S, Srinivasan VJ, Shin HK, Eikermann-Haerter K, Boas DA, Ayata C. Cortical spreading depression impairs oxygen delivery and metabolism in mice. J Cereb Blood Flow Metab. 2012 Feb; 32(2):376-86.
    View in: PubMed
  7. Baraghis E, Devor A, Fang Q, Srinivasan VJ, Wu W, Lesage F, Ayata C, Kasischke KA, Boas DA, Sakadzic S. Two-photon microscopy of cortical NADH fluorescence intensity changes: correcting contamination from the hemodynamic response. J Biomed Opt. 2011 Oct; 16(10):106003.
    View in: PubMed
  8. Devor A, Sakadzic S, Saisan PA, Yaseen MA, Roussakis E, Srinivasan VJ, Vinogradov SA, Rosen BR, Buxton RB, Dale AM, Boas DA. "Overshoot" of O2 is required to maintain baseline tissue oxygenation at locations distal to blood vessels. J Neurosci. 2011 Sep 21; 31(38):13676-81.
    View in: PubMed
  9. Carp SA, Roche-Labarbe N, Franceschini MA, Srinivasan VJ, Sakadžic S, Boas DA. Due to intravascular multiple sequential scattering, Diffuse Correlation Spectroscopy of tissue primarily measures relative red blood cell motion within vessels. Biomed Opt Express. 2011 Jul 1; 2(7):2047-54.
    View in: PubMed
  10. Sakadžic S, Roussakis E, Yaseen MA, Mandeville ET, Srinivasan VJ, Arai K, Ruvinskaya S, Wu W, Devor A, Lo EH, Vinogradov SA, Boas DA. J. Vis. Exp. Cerebral blood oxygenation measurement based on oxygen-dependent quenching of phosphorescence. 2011; (51).
  11. Tian P, Devor A, Sakadzic S, Dale AM, Boas DA. Monte Carlo simulation of the spatial resolution and depth sensitivity of two-dimensional optical imaging of the brain. J Biomed Opt. 2011 Jan-Feb; 16(1):016006.
    View in: PubMed
  12. Yaseen MA, Srinivasan VJ, Sakadžic S, Radhakrishnan H, Gorczynska I, Wu W, Fujimoto JG, Boas DA. Microvascular oxygen tension and flow measurements in rodent cerebral cortex during baseline conditions and functional activation. J Cereb Blood Flow Metab. 2011 Apr; 31(4):1051-63.
    View in: PubMed
  13. Sakadzic S, Roussakis E, Yaseen MA, Mandeville ET, Srinivasan VJ, Arai K, Ruvinskaya S, Devor A, Lo EH, Vinogradov SA, Boas DA. Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue. Nat Methods. 2010 Sep; 7(9):755-9.
    View in: PubMed
  14. Srinivasan VJ, Sakadzic S, Gorczynska I, Ruvinskaya S, Wu W, Fujimoto JG, Boas DA. Quantitative cerebral blood flow with optical coherence tomography. Opt Express. 2010 Feb 1; 18(3):2477-94.
    View in: PubMed
  15. Sukhotinsky I, Yaseen MA, Sakadzic S, Ruvinskaya S, Sims JR, Boas DA, Moskowitz MA, Ayata C. Perfusion pressure-dependent recovery of cortical spreading depression is independent of tissue oxygenation over a wide physiologic range. J Cereb Blood Flow Metab. 2010 Jun; 30(6):1168-77.
    View in: PubMed
  16. Yaseen MA, Srinivasan VJ, Sakadzic S, Wu W, Ruvinskaya S, Vinogradov SA, Boas DA. Optical monitoring of oxygen tension in cortical microvessels with confocal microscopy. Opt Express. 2009 Dec 7; 17(25):22341-50.
    View in: PubMed
  17. Srinivasan VJ, Sakadzic S, Gorczynska I, Ruvinskaya S, Wu W, Fujimoto JG, Boas DA. Depth-resolved microscopy of cortical hemodynamics with optical coherence tomography. Opt Lett. 2009 Oct 15; 34(20):3086-8.
    View in: PubMed
  18. Lebedev AY, Cheprakov AV, Sakadzic S, Boas DA, Wilson DF, Vinogradov SA. Dendritic phosphorescent probes for oxygen imaging in biological systems. ACS Appl Mater Interfaces. 2009 Jun; 1(6):1292-304.
    View in: PubMed
  19. Sakadzic S, Yuan S, Dilekoz E, Ruvinskaya S, Vinogradov SA, Ayata C, Boas DA. Simultaneous imaging of cerebral partial pressure of oxygen and blood flow during functional activation and cortical spreading depression. Appl Opt. 2009 Apr 1; 48(10):D169-77.
    View in: PubMed
  20. Sakadzic S, Demirbas U, Mempel TR, Moore A, Ruvinskaya S, Boas DA, Sennaroglu A, Kaertner FX, Fujimoto JG. Multi-photon microscopy with a low-cost and highly efficient Cr:LiCAF laser. Opt Express. 2008 Dec 8; 16(25):20848-63.
    View in: PubMed
  21. Fang Q, Sakadzic S, Ruvinskaya L, Devor A, Dale AM, Boas DA. Oxygen advection and diffusion in a three- dimensional vascular anatomical network. Opt Express. 2008 Oct 27; 16(22):17530-41.
    View in: PubMed
  22. Sakadzic S, Wang LV. Correlation transfer equation for multiply scattered light modulated by an ultrasonic pulse. J Opt Soc Am A Opt Image Sci Vis. 2007 Sep; 24(9):2797-806.
    View in: PubMed
  23. Kothapalli SR, Sakadzic S, Kim C, Wang LV. Imaging optically scattering objects with ultrasound-modulated optical tomography. Opt Lett. 2007 Aug 15; 32(16):2351-3.
    View in: PubMed
  24. Sakadzic S, Wang LV. Correlation transfer equation for ultrasound-modulated multiply scattered light. Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Sep; 74(3 Pt 2):036618.
    View in: PubMed
  25. Zemp R, Sakadzic S, Wang LV. Stochastic explanation of speckle contrast detection in ultrasound-modulated optical tomography. Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Jun; 73(6 Pt 1):061920.
    View in: PubMed
  26. Sakadzic S, Wang LV. Correlation transfer and diffusion of ultrasound-modulated multiply scattered light. Phys Rev Lett. 2006 Apr 28; 96(16):163902.
    View in: PubMed
  27. Sakadzic S, Wang LV. Modulation of multiply scattered coherent light by ultrasonic pulses: an analytical model. Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Sep; 72(3 Pt 2):036620.
    View in: PubMed
  28. Sakadzic S, Wang LV. High-resolution ultrasound-modulated optical tomography in biological tissues. Opt Lett. 2004 Dec 1; 29(23):2770-2.
    View in: PubMed
  29. Petrovic ZL, Sakadzic S, Spasojevic N, Matsui J, Makabe T. Mater. Sci. Forum. Comparison of direct numerical procedure and Monte Carlo technique to determine the charging effects in submicron structures. 2004; 453-454:9-14.
  30. Li J, Sakadzic S, Ku G, Wang LV. Transmission- and side-detection configurations in ultrasound-modulated optical tomography of thick biological tissues. Appl Opt. 2003 Jul 1; 42(19):4088-94.
    View in: PubMed
  31. Rahman A, Hammarsten EC, Sakadzic S, Rocca JJ, Wyart JF. Physica Scripta. Identification of n=4, Delta n=0 transitions in the spectra of nickel-like cadmium ions from a capillary discharge plasma column. 2003; 67(5):414-419.
  32. Sakadzic S, Wang LV. Ultrasonic modulation of multiply scattered coherent light: an analytical model for anisotropically scattering media. Phys Rev E Stat Nonlin Soft Matter Phys. 2002 Aug; 66(2 Pt 2):026603.
    View in: PubMed
  33. Raspopovic Z, Sakadzic S, Petrovic ZL, Makabe T. J. Phys. D: Appl. Phys. Diffusion of electrons in time-dependent E(t) x B(t) fields. 2000; 33(11):1298-1302.
  34. Dyatko NA, Napartovich AP, Sakadzic S, Petrovic Z, Raspopovic Z. J. Phys. D: Appl. Phys. On the possibility of negative electron mobility in a decaying plasma. 2000; 33(4):375-380.
  35. Raspopovic Z, Sakadzic S, Bzenic SA, Petrovic ZL. IEEE Trans. Plasma Sci. Benchmark calculations for Monte Carlo simulations of electron transport. 1999; 27(5):1241-1248.
  36. Bzenic S, Raspopovic ZM, Sakadzic S, Petrovic ZL. IEEE Trans. Plasma Sci. Relaxation of electron swarm energy distribution functions in time-varying fields. 1999; 27(1):78-79.
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