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Last Name
Institution

Jeffrey Theodore Borenstein, PH.D.

TitleInstructor in Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressPartners Research Building
Renal - HST Division
65 Landsdowne St
Cambridge MA 02139

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Kniazeva T, Epshteyn AA, Hsiao JC, Kim ES, Kolachalama VB, Charest JL, Borenstein JT. Performance and scaling effects in a multilayer microfluidic extracorporeal lung oxygenation device. Lab Chip. 2012 May 7; 12(9):1686-95.
    View in: PubMed
  2. Bellan LM, Kniazeva T, Kim ES, Epshteyn AA, Cropek DM, Langer R, Borenstein JT. Fabrication of a hybrid microfluidic system incorporating both lithographically patterned microchannels and a 3D fiber-formed microfluidic network. Adv Healthc Mater. 2012 Mar; 1(2):164-7.
    View in: PubMed
  3. Eda H, Kulig KM, Steiner TA, Shimada H, Patel K, Park E, Kim ES, Borenstein JT, Neville CM, Keller BT. A nanofiber membrane maintains the quiescent phenotype of hepatic stellate cells. Dig Dis Sci. 2012 May; 57(5):1152-62.
    View in: PubMed
  4. Pararas EE, Borkholder DA, Borenstein JT. Microsystems technologies for drug delivery to the inner ear. Adv Drug Deliv Rev. 2012 Nov; 64(14):1650-60.
    View in: PubMed
  5. Borenstein JT, Vunjak-Novakovic G. Engineering tissue with BioMEMS. IEEE Pulse. 2011 Nov; 2(6):28-34.
    View in: PubMed
  6. Inamdar NK, Borenstein JT. Microfluidic cell culture models for tissue engineering. Curr Opin Biotechnol. 2011 Oct; 22(5):681-9.
    View in: PubMed
  7. Inamdar NK, Griffith LG, Borenstein JT. Transport and shear in a microfluidic membrane bilayer device for cell culture. Biomicrofluidics. 2011 Jun; 5(2):22213.
    View in: PubMed
  8. Borenstein JT. Intracochlear drug delivery systems. Expert Opin Drug Deliv. 2011 Sep; 8(9):1161-74.
    View in: PubMed
  9. Kniazeva T, Hsiao JC, Charest JL, Borenstein JT. A microfluidic respiratory assist device with high gas permeance for artificial lung applications. Biomed Microdevices. 2011 Apr; 13(2):315-23.
    View in: PubMed
  10. Pararas EE, Chen Z, Fiering J, Mescher MJ, Kim ES, McKenna MJ, Kujawa SG, Borenstein JT, Sewell WF. Kinetics of reciprocating drug delivery to the inner ear. J Control Release. 2011 Jun 10; 152(2):270-7.
    View in: PubMed
  11. Wang J, Bettinger CJ, Langer RS, Borenstein JT. Biodegradable microfluidic scaffolds for tissue engineering from amino alcohol-based poly(ester amide) elastomers. Organogenesis. 2010 Oct-Dec; 6(4):212-6.
    View in: PubMed
  12. Hsu WM, Carraro A, Kulig KM, Miller ML, Kaazempur-Mofrad M, Weinberg E, Entabi F, Albadawi H, Watkins MT, Borenstein JT, Vacanti JP, Neville C. Liver-assist device with a microfluidics-based vascular bed in an animal model. Ann Surg. 2010 Aug; 252(2):351-7.
    View in: PubMed
  13. Hoganson DM, Anderson JL, Weinberg EF, Swart EJ, Orrick BK, Borenstein JT, Vacanti JP. Branched vascular network architecture: a new approach to lung assist device technology. J Thorac Cardiovasc Surg. 2010 Nov; 140(5):990-5.
    View in: PubMed
  14. McCall AA, Swan EE, Borenstein JT, Sewell WF, Kujawa SG, McKenna MJ. Drug delivery for treatment of inner ear disease: current state of knowledge. Ear Hear. 2010 Apr; 31(2):156-65.
    View in: PubMed
  15. Borenstein JT, Tupper MM, Mack PJ, Weinberg EJ, Khalil AS, Hsiao J, García-Cardeña G. Functional endothelialized microvascular networks with circular cross-sections in a tissue culture substrate. Biomed Microdevices. 2010 Feb; 12(1):71-9.
    View in: PubMed
  16. Bettinger CJ, Bruggeman JP, Borenstein JT, Langer R. In vitro and in vivo degradation of poly(1,3-diamino-2-hydroxypropane-co-polyol sebacate) elastomers. J Biomed Mater Res A. 2009 Dec 15; 91(4):1077-88.
    View in: PubMed
  17. Sewell WF, Borenstein JT, Chen Z, Fiering J, Handzel O, Holmboe M, Kim ES, Kujawa SG, McKenna MJ, Mescher MM, Murphy B, Swan EE, Peppi M, Tao S. Development of a microfluidics-based intracochlear drug delivery device. Audiol Neurootol. 2009; 14(6):411-22.
    View in: PubMed
  18. Fritsche CS, Simsch O, Weinberg EJ, Orrick B, Stamm C, Kaazempur-Mofrad MR, Borenstein JT, Hetzer R, Vacanti JP. Pulmonary tissue engineering using dual-compartment polymer scaffolds with integrated vascular tree. Int J Artif Organs. 2009 Oct; 32(10):701-10.
    View in: PubMed
  19. Freed LE, Engelmayr GC, Borenstein JT, Moutos FT, Guilak F. Advanced material strategies for tissue engineering scaffolds. Adv Mater. 2009 Sep 4; 21(32-33):3410-8.
    View in: PubMed
  20. Kendler DL, Bessette L, Hill CD, Gold DT, Horne R, Varon SF, Borenstein J, Wang H, Man HS, Wagman RB, Siddhanti S, Macarios D, Bone HG. Preference and satisfaction with a 6-month subcutaneous injection versus a weekly tablet for treatment of low bone mass. Osteoporos Int. 2010 May; 21(5):837-46.
    View in: PubMed
  21. Bettinger CJ, Kulig KM, Vacanti JP, Langer R, Borenstein JT. Nanofabricated collagen-inspired synthetic elastomers for primary rat hepatocyte culture. Tissue Eng Part A. 2009 Jun; 15(6):1321-9.
    View in: PubMed
  22. Fiering J, Mescher MJ, Leary Swan EE, Holmboe ME, Murphy BA, Chen Z, Peppi M, Sewell WF, McKenna MJ, Kujawa SG, Borenstein JT. Local drug delivery with a self-contained, programmable, microfluidic system. Biomed Microdevices. 2009 Jun; 11(3):571-8.
    View in: PubMed
  23. Handzel O, Wang H, Fiering J, Borenstein JT, Mescher MJ, Swan EE, Murphy BA, Chen Z, Peppi M, Sewell WF, Kujawa SG, McKenna MJ. Mastoid cavity dimensions and shape: method of measurement and virtual fitting of implantable devices. Audiol Neurootol. 2009; 14(5):308-14.
    View in: PubMed
  24. Ciocan R, Lenkinski RE, Bernstein J, Bancu M, Marquis R, Ivanishev A, Kourtelidis F, Matsui A, Borenstein J, Frangioni JV. MRI contrast using solid-state, B1-distorting, microelectromechanical systems (MEMS) microresonant devices (MRDs). Magn Reson Med. 2009 Apr; 61(4):860-6.
    View in: PubMed
  25. Bettinger CJ, Bruggeman JP, Misra A, Borenstein JT, Langer R. Biocompatibility of biodegradable semiconducting melanin films for nerve tissue engineering. Biomaterials. 2009 Jun; 30(17):3050-7.
    View in: PubMed
  26. Bettinger CJ, Langer R, Borenstein JT. Engineering substrate topography at the micro- and nanoscale to control cell function. Angew Chem Int Ed Engl. 2009; 48(30):5406-15.
    View in: PubMed
  27. Du Y, Shim J, Vidula M, Hancock MJ, Lo E, Chung BG, Borenstein JT, Khabiry M, Cropek DM, Khademhosseini A. Rapid generation of spatially and temporally controllable long-range concentration gradients in a microfluidic device. Lab Chip. 2009 Mar 21; 9(6):761-7.
    View in: PubMed
  28. Carraro A, Hsu WM, Kulig KM, Cheung WS, Miller ML, Weinberg EJ, Swart EF, Kaazempur-Mofrad M, Borenstein JT, Vacanti JP, Neville C. In vitro analysis of a hepatic device with intrinsic microvascular-based channels. Biomed Microdevices. 2008 Dec; 10(6):795-805.
    View in: PubMed
  29. Borenstein JT. Acting together, bacterial clusters initiate coagulation. Nat Chem Biol. 2008 Dec; 4(12):718-9.
    View in: PubMed
  30. Engelmayr GC, Cheng M, Bettinger CJ, Borenstein JT, Langer R, Freed LE. Accordion-like honeycombs for tissue engineering of cardiac anisotropy. Nat Mater. 2008 Dec; 7(12):1003-10.
    View in: PubMed
  31. Swan EE, Mescher MJ, Sewell WF, Tao SL, Borenstein JT. Inner ear drug delivery for auditory applications. Adv Drug Deliv Rev. 2008 Dec 14; 60(15):1583-99.
    View in: PubMed
  32. Weinberg E, Kaazempur-Mofrad M, Borenstein J. Concept and computational design for a bioartificial nephron-on-a-chip. Int J Artif Organs. 2008 Jun; 31(6):508-14.
    View in: PubMed
  33. Bettinger CJ, Bruggeman JP, Borenstein JT, Langer RS. Amino alcohol-based degradable poly(ester amide) elastomers. Biomaterials. 2008 May; 29(15):2315-25.
    View in: PubMed
  34. Mahdavi A, Ferreira L, Sundback C, Nichol JW, Chan EP, Carter DJ, Bettinger CJ, Patanavanich S, Chignozha L, Ben-Joseph E, Galakatos A, Pryor H, Pomerantseva I, Masiakos PT, Faquin W, Zumbuehl A, Hong S, Borenstein J, Vacanti J, Langer R, Karp JM. A biodegradable and biocompatible gecko-inspired tissue adhesive. Proc Natl Acad Sci U S A. 2008 Feb 19; 105(7):2307-12.
    View in: PubMed
  35. Carlen ET, Weinberg MS, Zapata AM, Borenstein JT. A micromachined surface stress sensor with electronic readout. Rev Sci Instrum. 2008 Jan; 79(1):015106.
    View in: PubMed
  36. Borenstein JT, Weinberg EJ, Orrick BK, Sundback C, Kaazempur-Mofrad MR, Vacanti JP. Microfabrication of three-dimensional engineered scaffolds. Tissue Eng. 2007 Aug; 13(8):1837-44.
    View in: PubMed
  37. Gerecht S, Bettinger CJ, Zhang Z, Borenstein JT, Vunjak-Novakovic G, Langer R. The effect of actin disrupting agents on contact guidance of human embryonic stem cells. Biomaterials. 2007 Oct; 28(28):4068-77.
    View in: PubMed
  38. Karp JM, Yeh J, Eng G, Fukuda J, Blumling J, Suh KY, Cheng J, Mahdavi A, Borenstein J, Langer R, Khademhosseini A. Controlling size, shape and homogeneity of embryoid bodies using poly(ethylene glycol) microwells. Lab Chip. 2007 Jun; 7(6):786-94.
    View in: PubMed
  39. Khademhosseini A, Langer R, Borenstein J, Vacanti JP. Microscale technologies for tissue engineering and biology. Proc Natl Acad Sci U S A. 2006 Feb 21; 103(8):2480-7.
    View in: PubMed
  40. Khademhosseini A, Bettinger C, Karp JM, Yeh J, Ling Y, Borenstein J, Fukuda J, Langer R. Interplay of biomaterials and micro-scale technologies for advancing biomedical applications. J Biomater Sci Polym Ed. 2006; 17(11):1221-40.
    View in: PubMed
  41. Bettinger CJ, Orrick B, Misra A, Langer R, Borenstein JT. Microfabrication of poly (glycerol-sebacate) for contact guidance applications. Biomaterials. 2006 Apr; 27(12):2558-65.
    View in: PubMed
  42. Chen Z, Kujawa SG, McKenna MJ, Fiering JO, Mescher MJ, Borenstein JT, Swan EE, Sewell WF. Inner ear drug delivery via a reciprocating perfusion system in the guinea pig. J Control Release. 2005 Dec 10; 110(1):1-19.
    View in: PubMed
  43. Khademhosseini A, Yeh J, Eng G, Karp J, Kaji H, Borenstein J, Farokhzad OC, Langer R. Cell docking inside microwells within reversibly sealed microfluidic channels for fabricating multiphenotype cell arrays. Lab Chip. 2005 Dec; 5(12):1380-6.
    View in: PubMed
  44. Fidkowski C, Kaazempur-Mofrad MR, Borenstein J, Vacanti JP, Langer R, Wang Y. Endothelialized microvasculature based on a biodegradable elastomer. Tissue Eng. 2005 Jan-Feb; 11(1-2):302-9.
    View in: PubMed
  45. Shin M, Matsuda K, Ishii O, Terai H, Kaazempur-Mofrad M, Borenstein J, Detmar M, Vacanti JP. Endothelialized networks with a vascular geometry in microfabricated poly(dimethyl siloxane). Biomed Microdevices. 2004 Dec; 6(4):269-78.
    View in: PubMed
  46. Ogawa K, Ochoa ER, Borenstein J, Tanaka K, Vacanti JP. The generation of functionally differentiated, three-dimensional hepatic tissue from two-dimensional sheets of progenitor small hepatocytes and nonparenchymal cells. Transplantation. 2004 Jun 27; 77(12):1783-9.
    View in: PubMed
  47. Rodby RA, Chiou CF, Borenstein J, Smitten A, Sengupta N, Palmer AJ, Roze S, Annemans L, Simon TA, Chen RS, Lewis EJ. The cost-effectiveness of irbesartan in the treatment of hypertensive patients with type 2 diabetic nephropathy. Clin Ther. 2003 Jul; 25(7):2102-19.
    View in: PubMed
  48. Kaihara S, Borenstein J, Koka R, Lalan S, Ochoa ER, Ravens M, Pien H, Cunningham B, Vacanti JP. Silicon micromachining to tissue engineer branched vascular channels for liver fabrication. Tissue Eng. 2000 Apr; 6(2):105-17.
    View in: PubMed
  49. Levine SP, Bell DA, Jaros LA, Simpson RC, Koren Y, Borenstein J. The NavChair Assistive Wheelchair Navigation System. IEEE Trans Rehabil Eng. 1999 Dec; 7(4):443-51.
    View in: PubMed
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