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Last Name
Institution

Eugene Jerome Mark, M.D.

TitleProfessor of Pathology
InstitutionMassachusetts General Hospital
DepartmentPathology
AddressMassachusetts General Hospital
Dept of Pathology
55 Fruit St
Boston MA 02114
Phone617/726-5915
Fax617/726-7474

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Dodson RF, Mark EJ, Poye LW. Biodurability/Retention of libby amphiboles in a case of mesothelioma. Ultrastruct Pathol. 2014 Feb; 38(1):45-51.
    View in: PubMed
  2. Kobraei EM, Song TH, Mathisen DJ, Deshpande V, Mark EJ. Immunoglobulin g4-related disease presenting as an obstructing tracheal mass: consideration of surgical indications. Ann Thorac Surg. 2013 Oct; 96(4):e91-3.
    View in: PubMed
  3. Hariri LP, Mino-Kenudson M, Applegate MB, Mark EJ, Tearney GJ, Lanuti M, Channick CL, Chee A, Suter MJ. Toward the guidance of transbronchial biopsy: identifying pulmonary nodules with optical coherence tomography. Chest. 2013 Oct; 144(4):1261-8.
    View in: PubMed
  4. Mohammad-Taheri Z, Nadji SA, Raisi F, Mohammadi F, Bahadori M, Mark EJ. No association between simian virus 40 and diffuse malignant mesothelioma of the pleura in Iranian patients: A molecular and epidemiologic case-control study of 60 patients. Am J Ind Med. 2013 Oct; 56(10):1221-5.
    View in: PubMed
  5. Onozato ML, Kovach AE, Yeap BY, Morales-Oyarvide V, Klepeis VE, Tammireddy S, Heist RS, Mark EJ, Dias-Santagata D, Iafrate AJ, Yagi Y, Mino-Kenudson M. Tumor Islands in Resected Early-stage Lung Adenocarcinomas are Associated With Unique Clinicopathologic and Molecular Characteristics and Worse Prognosis. Am J Surg Pathol. 2013 Feb; 37(2):287-94.
    View in: PubMed
  6. Hariri LP, Applegate MB, Mino-Kenudson M, Mark EJ, Bouma BE, Tearney GJ, Suter MJ. Optical Frequency Domain Imaging of Ex vivo Pulmonary Resection Specimens: Obtaining One to One Image to Histopathology Correlation. J Vis Exp. 2013; (71).
    View in: PubMed
  7. Hariri LP, Villiger M, Applegate MB, Mino-Kenudson M, Mark EJ, Bouma BE, Suter MJ. Seeing beyond the Bronchoscope to Increase the Diagnostic Yield of Bronchoscopic Biopsy. Am J Respir Crit Care Med. 2013 Jan 15; 187(2):125-9.
    View in: PubMed
  8. Hariri LP, Applegate MB, Mino-Kenudson M, Mark EJ, Medoff BD, Luster AD, Bouma BE, Tearney GJ, Suter MJ. Volumetric optical frequency domain imaging of pulmonary pathology with precise correlation to histopathology. Chest. 2013 Jan; 143(1):64-74.
    View in: PubMed
  9. Hariri LP, Mino-Kenudson M, Mark EJ, Suter MJ. In vivo optical coherence tomography: the role of the pathologist. Arch Pathol Lab Med. 2012 Dec; 136(12):1492-501.
    View in: PubMed
  10. Christopher-Stine L, Robinson DR, Wu CC, Mark EJ. Case records of the Massachusetts General Hospital. Case 37-2012. A 21-year-old man with fevers, arthralgias, and pulmonary infiltrates. N Engl J Med. 2012 Nov 29; 367(22):2134-46.
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  11. Nishino M, Klepeis VE, Yeap BY, Bergethon K, Morales-Oyarvide V, Dias-Santagata D, Yagi Y, Mark EJ, Iafrate AJ, Mino-Kenudson M. Histologic and cytomorphologic features of ALK-rearranged lung adenocarcinomas. Mod Pathol. 2012 Nov; 25(11):1462-72.
    View in: PubMed
  12. Wu RI, Mark EJ, Hunt JL. Staining for acid-fast bacilli in surgical pathology: practice patterns and variations. Hum Pathol. 2012 Nov; 43(11):1845-51.
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  13. Lee MS, Asomaning K, Su L, Wain JC, Mark EJ, Christiani DC. MTHFR polymorphisms, folate intake and carcinogen DNA adducts in the lung. Int J Cancer. 2012 Sep 1; 131(5):1203-9.
    View in: PubMed
  14. Bergethon K, Shaw AT, Ou SH, Katayama R, Lovly CM, McDonald NT, Massion PP, Siwak-Tapp C, Gonzalez A, Fang R, Mark EJ, Batten JM, Chen H, Wilner KD, Kwak EL, Clark JW, Carbone DP, Ji H, Engelman JA, Mino-Kenudson M, Pao W, Iafrate AJ. ROS1 rearrangements define a unique molecular class of lung cancers. J Clin Oncol. 2012 Mar 10; 30(8):863-70.
    View in: PubMed
  15. Martinez F, Chung JH, Digumarthy SR, Kanne JP, Abbott GF, Shepard JA, Mark EJ, Sharma A. Common and uncommon manifestations of Wegener granulomatosis at chest CT: radiologic-pathologic correlation. Radiographics. 2012 Jan-Feb; 32(1):51-69.
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  16. Yagi Y, Yoshioka S, Kyusojin H, Onozato M, Mizutani Y, Osato K, Yada H, Mark EJ, Frosch MP, Louis DN. An ultra-high speed whole slide image viewing system. Stud Health Technol Inform. 2012; 179:239-49.
    View in: PubMed
  17. Yagi Y, Yoshioka S, Kyusojin H, Onozato M, Mizutani Y, Osato K, Yada H, Mark EJ, Frosch MP, Louis DN. An ultra-high speed whole slide image viewing system. Anal Cell Pathol (Amst). 2012; 35(1):65-73.
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  18. Wirbelauer J, Hebestreit H, Marx A, Mark EJ, Speer CP. Familial pulmonary capillary hemangiomatosis early in life. Case Rep Pulmonol. 2011; 2011:827591.
    View in: PubMed
  19. Kinane TB, Shailam R, Mark EJ. Case records of the Massachusetts General Hospital. Case 37-2011. A 9-month-old boy with recurrent tachypnea and respiratory distress. N Engl J Med. 2011 Dec 8; 365(23):2221-8.
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  20. Tse SM, Kinane TB, Mark EJ, Haver KE. An 11-year-old boy with respiratory failure and massive pleural fluid drainage. Chest. 2011 Dec; 140(6):1659-61.
    View in: PubMed
  21. Yonker LM, Mark EJ, Canapari CA. Aspergilloma in a patient with an occult congenital pulmonary airway malformation. Pediatr Pulmonol. 2012 Mar; 47(3):308-10.
    View in: PubMed
  22. Nishino M, Medoff BD, Mark EJ, Matsubara O, O'Donnell WJ, Currier PF, Kradin RL. Variant alveolar lipoproteinosis: a syndrome with distinct clinical and pathological features. Pathol Int. 2011 Sep; 61(9):509-17.
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  23. Hariri LP, Mino-Kenudson M, Shea B, Digumarthy S, Onozato M, Yagi Y, Fraire AE, Matsubara O, Mark EJ. Distinct histopathology of acute onset or abrupt exacerbation of hypersensitivity pneumonitis. Hum Pathol. 2012 May; 43(5):660-8.
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  24. Mino-Kenudson M, Mark EJ. Reflex testing for epidermal growth factor receptor mutation and anaplastic lymphoma kinase fluorescence in situ hybridization in non-small cell lung cancer. Arch Pathol Lab Med. 2011 May; 135(5):655-64.
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  25. Sequist LV, Waltman BA, Dias-Santagata D, Digumarthy S, Turke AB, Fidias P, Bergethon K, Shaw AT, Gettinger S, Cosper AK, Akhavanfard S, Heist RS, Temel J, Christensen JG, Wain JC, Lynch TJ, Vernovsky K, Mark EJ, Lanuti M, Iafrate AJ, Mino-Kenudson M, Engelman JA. Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors. Sci Transl Med. 2011 Mar 23; 3(75):75ra26.
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  26. Lee MS, Su L, Mark EJ, Wain JC, Christiani DC. Genetic modifiers of carcinogen DNA adducts in target lung and peripheral blood mononuclear cells. Carcinogenesis. 2010 Dec; 31(12):2091-6.
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  27. Hariri LP, Unizony S, Stone J, Mino-Kenudson M, Sharma A, Matsubara O, Mark EJ. Acute fibrinous and organizing pneumonia in systemic lupus erythematosus: a case report and review of the literature. Pathol Int. 2010 Nov; 60(11):755-9.
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  28. Kradin RL, Digumarthy SR, Baggish AL, Mark EJ. Case records of the Massachusetts General Hospital. Case 12-2010. An 89-year-old man with progressive dyspnea. N Engl J Med. 2010 Apr 22; 362(16):1522-31.
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  29. Honings J, Gaissert HA, Weinberg AC, Mark EJ, Wright CD, Wain JC, Mathisen DJ. Prognostic value of pathologic characteristics and resection margins in tracheal adenoid cystic carcinoma. Eur J Cardiothorac Surg. 2010 Jun; 37(6):1438-44.
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  30. Mino-Kenudson M, Chirieac LR, Law K, Hornick JL, Lindeman N, Mark EJ, Cohen DW, Johnson BE, Jänne PA, Iafrate AJ, Rodig SJ. A novel, highly sensitive antibody allows for the routine detection of ALK-rearranged lung adenocarcinomas by standard immunohistochemistry. Clin Cancer Res. 2010 Mar 1; 16(5):1561-71.
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  31. Wilbur DC, Madi K, Colvin RB, Duncan LM, Faquin WC, Ferry JA, Frosch MP, Houser SL, Kradin RL, Lauwers GY, Louis DN, Mark EJ, Mino-Kenudson M, Misdraji J, Nielsen GP, Pitman MB, Rosenberg AE, Smith RN, Sohani AR, Stone JR, Tambouret RH, Wu CL, Young RH, Zembowicz A, Klietmann W. Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlations. Arch Pathol Lab Med. 2009 Dec; 133(12):1949-53.
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  32. Honings J, Gaissert HA, Ruangchira-Urai R, Wain JC, Wright CD, Mathisen DJ, Mark EJ. Pathologic characteristics of resected squamous cell carcinoma of the trachea: prognostic factors based on an analysis of 59 cases. Virchows Arch. 2009 Nov; 455(5):423-9.
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  33. Tager AM, Sharma A, Mark EJ. Case records of the Massachusetts General Hospital. Case 32-2009. A 27-year-old man with progressive dyspnea. N Engl J Med. 2009 Oct 15; 361(16):1585-93.
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  34. Farris AB, Hasserjian RP, Zukerberg LR, Amrein PC, Greene RE, Mark EJ, Kradin RL. Diffuse cellular and fibrosing interstitial pneumonitis with desquamative interstitial pneumonitis-like features associated with myeloid neoplasia. Am J Surg Pathol. 2009 Oct; 33(10):1485-93.
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  35. Lin HW, Tierney HT, Richmon JD, Mark EJ, Deschler DG. Extrusion of embolization coils through the carotid artery in a radiated neck. Auris Nasus Larynx. 2010 Jun; 37(3):390-3.
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  36. Rodig SJ, Mino-Kenudson M, Dacic S, Yeap BY, Shaw A, Barletta JA, Stubbs H, Law K, Lindeman N, Mark E, Janne PA, Lynch T, Johnson BE, Iafrate AJ, Chirieac LR. Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population. Clin Cancer Res. 2009 Aug 15; 15(16):5216-23.
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  37. Shaw AT, Yeap BY, Mino-Kenudson M, Digumarthy SR, Costa DB, Heist RS, Solomon B, Stubbs H, Admane S, McDermott U, Settleman J, Kobayashi S, Mark EJ, Rodig SJ, Chirieac LR, Kwak EL, Lynch TJ, Iafrate AJ. Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK. J Clin Oncol. 2009 Sep 10; 27(26):4247-53.
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  38. Ruangchira-urai R, Mark EJ. Lymphangiomatoid pattern in diffuse malignant mesothelioma of the pleura: a report of six cases. Virchows Arch. 2009 Aug; 455(2):143-8.
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  39. Jordan KW, Adkins CB, Su L, Halpern EF, Mark EJ, Christiani DC, Cheng LL. Comparison of squamous cell carcinoma and adenocarcinoma of the lung by metabolomic analysis of tissue-serum pairs. Lung Cancer. 2010 Apr; 68(1):44-50.
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  40. Gaissert HA, Piyavisetpat N, Mark EJ. Case records of the Massachusetts General Hospital. Case 14-2009. A 36-year-old man with chest pain, dysphagia, and pleural and mediastinal calcifications. N Engl J Med. 2009 Apr 30; 360(18):1886-95.
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  41. Cros D, Gonzalez RG, Mark EJ. Case records of the Massachusetts General Hospital. Case 6-2009. A 37-year-old woman with vertigo, facial weakness, and a generalized seizure. N Engl J Med. 2009 Feb 19; 360(8):802-9.
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  42. Steiner MK, Syrkina OL, Kolliputi N, Mark EJ, Hales CA, Waxman AB. Interleukin-6 overexpression induces pulmonary hypertension. Circ Res. 2009 Jan 30; 104(2):236-44, 28p following 244.
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  43. Ruangchira-Urai R, Colby TV, Klein J, Nielsen GP, Kradin RL, Mark EJ. Nodular amiodarone lung disease. Am J Surg Pathol. 2008 Nov; 32(11):1654-60.
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  44. Wiener CM, Muse VV, Mark EJ. Case records of the Massachusetts General Hospital. Case 33-2008. A 63-year-old woman with dyspnea on exertion. N Engl J Med. 2008 Oct 23; 359(17):1823-32.
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  45. Mark EJ, Meng F, Kradin RL, Mathisen DJ, Matsubara O. Idiopathic tracheal stenosis: a clinicopathologic study of 63 cases and comparison of the pathology with chondromalacia. Am J Surg Pathol. 2008 Aug; 32(8):1138-43.
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  46. Mandal RV, Mark EJ, Kradin RL. Organizing pneumonia and pulmonary lymphatic architecture in diffuse alveolar damage. Hum Pathol. 2008 Aug; 39(8):1234-8.
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  47. Mark EJ, Ruangchira-Urai R, Kradin RL. Shirt-sleeve or scanning magnification as an aid to the diagnosis of commonly encountered medical lung diseases. Arch Pathol Lab Med. 2008 Apr; 132(4):539-47.
    View in: PubMed
  48. Mark EJ, Ferry JA, Rosenberg AE, Young RH. Introduction to selected reviews based on the Massachusetts General Hospital, Harvard Medical School postgraduate course: "Current concepts in surgical pathology". Arch Pathol Lab Med. 2008 Apr; 132(4):537-8.
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  49. Kradin RL, Mark EJ. The pathology of pulmonary disorders due to Aspergillus spp. Arch Pathol Lab Med. 2008 Apr; 132(4):606-14.
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  50. Haver KE, Hartnick CJ, Ryan DP, Shailam R, Mark EJ. Case records of the Massachusetts General Hospital. Case 10-2008. A 10-year-old girl with dyspnea on exertion. N Engl J Med. 2008 Mar 27; 358(13):1382-90.
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  51. Mark EJ, Ruangchira-urai R. Bronchiolitis interstitial pneumonitis: a pathologic study of 31 lung biopsies with features intermediate between bronchiolitis obliterans organizing pneumonia and usual interstitial pneumonitis, with clinical correlation. Ann Diagn Pathol. 2008 Jun; 12(3):171-80.
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  52. Mandal RV, Mark EJ, Kradin RL. Megakaryocytes and platelet homeostasis in diffuse alveolar damage. Exp Mol Pathol. 2007 Dec; 83(3):327-31.
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  53. Finberg KE, Sequist LV, Joshi VA, Muzikansky A, Miller JM, Han M, Beheshti J, Chirieac LR, Mark EJ, Iafrate AJ. Mucinous differentiation correlates with absence of EGFR mutation and presence of KRAS mutation in lung adenocarcinomas with bronchioloalveolar features. J Mol Diagn. 2007 Jul; 9(3):320-6.
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  54. Wechsler ME, Shepard JA, Mark EJ. Case records of the Massachusetts General Hospital. Case 15-2007. A 20-year-old woman with asthma and cardiorespiratory arrest. N Engl J Med. 2007 May 17; 356(20):2083-91.
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  55. Brachtel EF, Iafrate AJ, Mark EJ, Deshpande V. Cytomorphological correlates of epidermal growth factor receptor mutations in lung carcinoma. Diagn Cytopathol. 2007 May; 35(5):257-62.
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  56. Farris AB, Mark EJ, Kradin RL. Pulmonary "inflammatory myofibroblastic" tumors: a critical examination of the diagnostic category based on quantitative immunohistochemical analysis. Virchows Arch. 2007 May; 450(5):585-90.
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  57. Hull MJ, Nazarian RM, Wheeler AE, Black-Schaffer WS, Mark EJ. Resident physician opinions on autopsy importance and procurement. Hum Pathol. 2007 Feb; 38(2):342-50.
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  58. Gaissert HA, Mark EJ. Tracheobronchial gland tumors. Cancer Control. 2006 Oct; 13(4):286-94.
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  59. Beheshti J, Mark EJ, Akbaei HM, Aslani J, Ghanei M. Mustard lung secrets: long term clinicopathological study following mustard gas exposure. Pathol Res Pract. 2006; 202(10):739-44.
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  60. Sequist LV, Joshi VA, Jänne PA, Bell DW, Fidias P, Lindeman NI, Louis DN, Lee JC, Mark EJ, Longtine J, Verlander P, Kucherlapati R, Meyerson M, Haber DA, Johnson BE, Lynch TJ. Epidermal growth factor receptor mutation testing in the care of lung cancer patients. Clin Cancer Res. 2006 Jul 15; 12(14 Pt 2):4403s-4408s.
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  61. Kradin RL, Mark EJ. Distinguishing benign mesothelial hyperplasia from neoplasia: a practical approach. Semin Diagn Pathol. 2006 Feb; 23(1):4-14.
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  62. Mark EJ, Kradin RL. Pathological recognition of diffuse malignant mesothelioma of the pleura: the significance of the historical perspective as regards this signal tumor. Semin Diagn Pathol. 2006 Feb; 23(1):25-34.
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  63. Kradin R, Matsubara O, Mark EJ. Endothelial nitric oxide synthase expression in pulmonary capillary hemangiomatosis. Exp Mol Pathol. 2005 Dec; 79(3):194-7.
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  64. Graham BB, Mathisen DJ, Mark EJ, Takvorian RW. Primary pulmonary lymphoma. Ann Thorac Surg. 2005 Oct; 80(4):1248-53.
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  65. Várkonyi A, Kelsey K, Semey K, Bodell WJ, Lévay G, Mark E, Wain JC, Christiani DC, Wiencke JK. Polyphenol associated-DNA adducts in lung and blood mononuclear cells from lung cancer patients. Cancer Lett. 2006 May 8; 236(1):24-31.
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  66. Miyagawa-Hayashino A, Wain JC, Mark EJ. Lung transplantation biopsy specimens with bronchiolitis obliterans or bronchiolitis obliterans organizing pneumonia due to aspiration. Arch Pathol Lab Med. 2005 Feb; 129(2):223-6.
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  67. Lynch TJ, Wright CD, Choi NC, Aquino SL, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 26-2004. A 56-year-old woman with cough and a lung nodule. N Engl J Med. 2004 Aug 19; 351(8):809-17.
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  68. Guimaraes AR, Wain JC, Mark EJ, Wittram C. Mucinous cystadenoma of the lung. AJR Am J Roentgenol. 2004 Aug; 183(2):282.
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  69. Nardell EA, Fan D, Shepard JA, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 22-2004. A 30-year-old woman with a pericardial effusion. N Engl J Med. 2004 Jul 15; 351(3):279-87.
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  70. Nakatani Y, Miyagi Y, Takemura T, Oka T, Yokoi T, Takagi M, Yokoyama S, Kashima K, Hara K, Yamada T, Nozawa A, Inayama Y, Sakamoto K, Ogawa N, Kitamura H, Resl M, Cho SH, Koss MN, Mark EJ. Aberrant nuclear/cytoplasmic localization and gene mutation of beta-catenin in classic pulmonary blastoma: beta-catenin immunostaining is useful for distinguishing between classic pulmonary blastoma and a blastomatoid variant of carcinosarcoma. Am J Surg Pathol. 2004 Jul; 28(7):921-7.
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  71. Nakatani Y, Masudo K, Nozawa A, Inayama Y, Yamanaka S, Ito T, Kitamura H, Notohara K, Kashima K, Yokoyama S, Tsujimoto M, Tamai S, Abe Y, Resl M, Mark EJ. Biotin-rich, optically clear nuclei express estrogen receptor-beta: tumors with morules may develop under the influence of estrogen and aberrant beta-catenin expression. Hum Pathol. 2004 Jul; 35(7):869-74.
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  72. Patel SR, Karmpaliotis D, Ayas NT, Mark EJ, Wain J, Thompson BT, Malhotra A. The role of open-lung biopsy in ARDS. Chest. 2004 Jan; 125(1):197-202.
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  73. Cai YC, Roggli V, Mark E, Cagle PT, Fraire AE. Transforming growth factor alpha and epidermal growth factor receptor in reactive and malignant mesothelial proliferations. Arch Pathol Lab Med. 2004 Jan; 128(1):68-70.
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  74. Ginns LC, Roberts DH, Mark EJ, Brusch JL, Marler JJ. Pulmonary capillary hemangiomatosis with atypical endotheliomatosis: successful antiangiogenic therapy with doxycycline. Chest. 2003 Nov; 124(5):2017-22.
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  75. Wittram C, Mark EJ, McLoud TC. CT-histologic correlation of the ATS/ERS 2002 classification of idiopathic interstitial pneumonias. Radiographics. 2003 Sep-Oct; 23(5):1057-71.
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  76. Schattner A, Aviel-Ronen S, Mark EJ. Accelerated usual interstitial pneumonitis, anti-DNA antibodies and hypocomplementemia. J Intern Med. 2003 Aug; 254(2):193-6.
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  77. Abi-Nassif S, Mark EJ, Fogel RB, Hallisey RK. Pegylated interferon and ribavirin-induced interstitial pneumonitis with ARDS. Chest. 2003 Jul; 124(1):406-10.
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  78. Fleming CM, Shepard JA, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 15-2003. A 47-year-old man with waxing and waning pulmonary nodules five years after treatment for testicular seminoma. N Engl J Med. 2003 May 15; 348(20):2019-27.
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  79. Waxman AB, Shepard JA, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 14-2003. A 73-year-old woman with pneumonia and progressive respiratory failure. N Engl J Med. 2003 May 8; 348(19):1902-12.
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  80. Malhotra A, Muse VV, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 12-2003. An 82-year-old man with dyspnea and pulmonary abnormalities. N Engl J Med. 2003 Apr 17; 348(16):1574-85.
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  81. Rubin RH, King ME, Mark EJ. Case record of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 7-2003. A 43-year-old man with fever, rapid loss of vision in the left eye, and cardiac findings. N Engl J Med. 2003 Feb 27; 348(9):834-43.
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  82. Wittram C, Fischman AJ, Mark E, Ko J, Shepard JA. Thymic enlargement and FDG uptake in three patients: CT and FDG positron emission tomography correlated with pathology. AJR Am J Roentgenol. 2003 Feb; 180(2):519-22.
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  83. Tanoue LT, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 1-2003. A 43-year-old man with fever and night sweats. N Engl J Med. 2003 Jan 9; 348(2):151-61.
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  84. Lowe HC, Mino M, Mark EJ, Mac Neill BD, Palacios IF, Houser SL. Histopathology of coronary in-stent restenosis following gamma brachytherapy. Heart. 2003 Jan; 89(1):11-3.
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  85. Gong MN, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 40-2002. A 56-year-old man with rapidly worsening dyspnea. N Engl J Med. 2002 Dec 26; 347(26):2149-57.
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  86. Rigby WF, Fan CM, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 39-2002--a 35-year-old man with headache, deviation of the tongue, and unusual radiographic abnormalities. N Engl J Med. 2002 Dec 19; 347(25):2057-65.
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  87. Silverman ES, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 36-2002. A 32-year-old man with hemoptysis of nearly three decades' duration. N Engl J Med. 2002 Nov 21; 347(21):1693-701.
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  88. Mushlin SB, Drazen JM, Samuels MA, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2002. A 28-year-old woman with ocular inflammation, fever, and headache. N Engl J Med. 2002 Oct 24; 347(17):1350-7.
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  89. Rajagopol J, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 32-2002. A 58-year-old man with interstitial pulmonary disease. N Engl J Med. 2002 Oct 17; 347(16):1262-8.
    View in: PubMed
  90. Hoadley DJ, Mark EJ. Case records of the Massachusetts General Hospital. Weekly Clinicopathological exercises. Case 28-2002. A 35-year-old long-term traveler with a rapidly progressive soft-tissue infection. N Engl J Med. 2002 Sep 12; 347(11):831-7.
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  91. McGowan K, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 25-2002. A 46-year-old woman with extensive pulmonary infiltrates. N Engl J Med. 2002 Aug 15; 347(7):517-24.
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  92. Imai Y, Mark EJ. Cystic adenomatoid change is common to various forms of cystic lung diseases of children: a clinicopathologic analysis of 10 cases with emphasis on tracing the bronchial tree. Arch Pathol Lab Med. 2002 Aug; 126(8):934-40.
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  93. Docken WP, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 23-2002. A 73-year-old man with leg pains, occipital headaches, and night sweats. N Engl J Med. 2002 Jul 25; 347(4):272-8.
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  94. Noble JT, Mark EJ. Case Records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 22-2002. A 37-year-old man with unexplained fever after a long trip through South America. N Engl J Med. 2002 Jul 18; 347(3):200-6.
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  95. Kradin RL, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 18-2002. A 48-year-old man with a cough and bloody sputum. N Engl J Med. 2002 Jun 13; 346(24):1892-9.
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  96. Nakatani Y, Masudo K, Miyagi Y, Inayama Y, Kawano N, Tanaka Y, Kato K, Ito T, Kitamura H, Nagashima Y, Yamanaka S, Nakamura N, Sano J, Ogawa N, Ishiwa N, Notohara K, Resl M, Mark EJ. Aberrant nuclear localization and gene mutation of beta-catenin in low-grade adenocarcinoma of fetal lung type: up-regulation of the Wnt signaling pathway may be a common denominator for the development of tumors that form morules. Mod Pathol. 2002 Jun; 15(6):617-24.
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  97. Aird WC, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 15-200. A 53-year-old man with a myocardial infarct and thromboses after coronary-artery bypass grafting. N Engl J Med. 2002 May 16; 346(20):1562-70.
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  98. Daly JS, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 14-2002. A 51-year-old woman with recurrent hemoptysis. N Engl J Med. 2002 May 9; 346(19):1475-82.
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  99. Huang Q, Muzitansky A, Mark EJ. Pulmonary neuroendocrine carcinomas. A review of 234 cases and a statistical analysis of 50 cases treated at one institution using a simple clinicopathologic classification. Arch Pathol Lab Med. 2002 May; 126(5):545-53.
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  100. Padera TP, Kadambi A, di Tomaso E, Carreira CM, Brown EB, Boucher Y, Choi NC, Mathisen D, Wain J, Mark EJ, Munn LL, Jain RK. Lymphatic metastasis in the absence of functional intratumor lymphatics. Science. 2002 Jun 7; 296(5574):1883-6.
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  101. Markowitz DH, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 13-2002. A 43-year-old man with renal carcinoma and worsening dyspnea. N Engl J Med. 2002 Apr 25; 346(17):1309-17.
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  102. Singhal AB, Caviness VS, Begleiter AF, Mark EJ, Rordorf G, Koroshetz WJ. Cerebral vasoconstriction and stroke after use of serotonergic drugs. Neurology. 2002 Jan 8; 58(1):130-3.
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  103. Bhattacharjee A, Richards WG, Staunton J, Li C, Monti S, Vasa P, Ladd C, Beheshti J, Bueno R, Gillette M, Loda M, Weber G, Mark EJ, Lander ES, Wong W, Johnson BE, Golub TR, Sugarbaker DJ, Meyerson M. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc Natl Acad Sci U S A. 2001 Nov 20; 98(24):13790-5.
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  104. Kim DH, Nelson HH, Wiencke JK, Zheng S, Christiani DC, Wain JC, Mark EJ, Kelsey KT. p16(INK4a) and histology-specific methylation of CpG islands by exposure to tobacco smoke in non-small cell lung cancer. Cancer Res. 2001 Apr 15; 61(8):3419-24.
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  105. Kim DH, Nelson HH, Wiencke JK, Christiani DC, Wain JC, Mark EJ, Kelsey KT. Promoter methylation of DAP-kinase: association with advanced stage in non-small cell lung cancer. Oncogene. 2001 Mar 29; 20(14):1765-70.
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  106. Hirao T, Nelson HH, Ashok TD, Wain JC, Mark EJ, Christiani DC, Wiencke JK, Kelsey KT. Tobacco smoke-induced DNA damage and an early age of smoking initiation induce chromosome loss at 3p21 in lung cancer. Cancer Res. 2001 Jan 15; 61(2):612-5.
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  107. Mandel J, Mark EJ, Hales CA. Pulmonary veno-occlusive disease. Am J Respir Crit Care Med. 2000 Nov; 162(5):1964-73.
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  108. Houser SL, Mark EJ. Bronchocentric granulomatosis with mucus impaction due to bronchogenic carcinoma. An association with clinical relevance. Arch Pathol Lab Med. 2000 Aug; 124(8):1168-71.
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  109. Chang HT, Yantiss RK, Nielsen GP, McKee GT, Mark EJ. Lipid-rich diffuse malignant mesothelioma: a case report. Hum Pathol. 2000 Jul; 31(7):876-9.
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  110. Duell EJ, Wiencke JK, Cheng TJ, Varkonyi A, Zuo ZF, Ashok TD, Mark EJ, Wain JC, Christiani DC, Kelsey KT. Polymorphisms in the DNA repair genes XRCC1 and ERCC2 and biomarkers of DNA damage in human blood mononuclear cells. Carcinogenesis. 2000 May; 21(5):965-71.
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  111. Cullen AR, Cannon CL, Mark EJ, Colin AA. Mycobacterium abscessus infection in cystic fibrosis. Colonization or infection? Am J Respir Crit Care Med. 2000 Feb; 161(2 Pt 1):641-5.
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  112. Nelson HH, Christiani DC, Mark EJ, Wiencke JK, Wain JC, Kelsey KT. Implications and prognostic value of K-ras mutation for early-stage lung cancer in women. J Natl Cancer Inst. 1999 Dec 1; 91(23):2032-8.
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  113. Keel SB, Bacha E, Mark EJ, Nielsen GP, Rosenberg AE. Primary pulmonary sarcoma: a clinicopathologic study of 26 cases. Mod Pathol. 1999 Dec; 12(12):1124-31.
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  114. Okubo K, Mark EJ, Flieder D, Wain JC, Wright CD, Moncure AC, Grillo HC, Mathisen DJ. Bronchoalveolar carcinoma: clinical, radiologic, and pathologic factors and survival. J Thorac Cardiovasc Surg. 1999 Oct; 118(4):702-9.
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  115. Abendstein B, Auer A, Pümpel R, Mark E, Desch B, Tscharf J. [Epignathus: prenatal diagnosis by sonography and magnetic resonance imaging]. Ultraschall Med. 1999 Oct; 20(5):207-11.
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  116. Nelson HH, Christiani DC, Wiencke JK, Mark EJ, Wain JC, Kelsey KT. k-ras mutation and occupational asbestos exposure in lung adenocarcinoma: asbestos-related cancer without asbestosis. Cancer Res. 1999 Sep 15; 59(18):4570-3.
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  117. Wang X, Christiani DC, Mark EJ, Nelson H, Wiencke JK, Gunn L, Wain JC, Kelsey KT. Carcinogen exposure, p53 alteration, and K-ras mutation in synchronous multiple primary lung carcinoma. Cancer. 1999 Apr 15; 85(8):1734-9.
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  118. Wiencke JK, Thurston SW, Kelsey KT, Varkonyi A, Wain JC, Mark EJ, Christiani DC. Early age at smoking initiation and tobacco carcinogen DNA damage in the lung. J Natl Cancer Inst. 1999 Apr 7; 91(7):614-9.
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  119. Kagata Y, Matsubara O, Ogata S, Lie JT, Mark EJ. Infantile disseminated visceral giant cell arteritis presenting as sudden infant death. Pathol Int. 1999 Mar; 49(3):226-30.
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  120. Flieder DB, Moran CA, Travis WD, Koss MN, Mark EJ. Pleuro-pulmonary endometriosis and pulmonary ectopic deciduosis: a clinicopathologic and immunohistochemical study of 10 cases with emphasis on diagnostic pitfalls. Hum Pathol. 1998 Dec; 29(12):1495-503.
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  121. Nakatani Y, Kitamura H, Inayama Y, Kamijo S, Nagashima Y, Shimoyama K, Nakamura N, Sano J, Ogawa N, Shibagaki T, Resl M, Mark EJ. Pulmonary adenocarcinomas of the fetal lung type: a clinicopathologic study indicating differences in histology, epidemiology, and natural history of low-grade and high-grade forms. Am J Surg Pathol. 1998 Apr; 22(4):399-411.
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  122. Sabatine MS, Oelberg DA, Mark EJ, Kanarek D. Pulmonary cholesterol crystal embolization. Chest. 1997 Dec; 112(6):1687-92.
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  123. Boiselle PM, Shepard JA, Mark EJ, Szyfelbein WM, Fan CM, Slanetz PJ, Trotman-Dickenson B, Halpern EF, Miller SW, McLoud TC. Routine addition of an automated biopsy device to fine-needle aspiration of the lung: a prospective assessment. AJR Am J Roentgenol. 1997 Sep; 169(3):661-6.
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  124. Mark EJ, Patalas ED, Chang HT, Evans RJ, Kessler SC. Fatal pulmonary hypertension associated with short-term use of fenfluramine and phentermine. N Engl J Med. 1997 Aug 28; 337(9):602-6.
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  125. Nakatani Y, Inayama Y, Kitamura H, Mark EJ. Mutations in the p53 gene in pulmonary blastomas. Hum Pathol. 1997 Jul; 28(7):873-4.
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  126. Scully RE, Mark EJ, McNeely WF, Ebeling SH, Phillips LD. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 20-1997. A 74-year-old man with progressive cough, dyspnea, and pleural thickening. N Engl J Med. 1997 Jun 26; 336(26):1895-903.
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  127. Mark EJ, Flieder DB, Matsubara O. Treated Wegener's granulomatosis: distinctive pathological findings in the lungs of 20 patients and what they tell us about the natural history of the disease. Hum Pathol. 1997 Apr; 28(4):450-8.
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  128. Villanueva AG, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 24-1996. A 54-year-old woman with infiltrative lung disease and mild dyspnea. N Engl J Med. 1996 Aug 8; 335(6):417-24.
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  129. Zhuang Z, Vortmeyer AO, Mark EJ, Odze R, Emmert-Buck MR, Merino MJ, Moon H, Liotta LA, Duray PH. Barrett's esophagus: metaplastic cells with loss of heterozygosity at the APC gene locus are clonal precursors to invasive adenocarcinoma. Cancer Res. 1996 May 1; 56(9):1961-4.
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  130. Huncharek M, Kelsey K, Mark EJ, Muscat J, Choi N, Carey R, Christiani D. Treatment and survival in diffuse malignant pleural mesothelioma; a study of 83 cases from the Massachusetts General Hospital. Anticancer Res. 1996 May-Jun; 16(3A):1265-8.
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  131. Matsubara O, Yoshimura N, Doi Y, Tamura A, Mark EJ. Nasal biopsy in the early diagnosis of Wegener's (pathergic) granulomatosis. Significance of palisading granuloma and leukocytoclastic vasculitis. Virchows Arch. 1996 Apr; 428(1):13-9.
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  132. Wiencke JK, Kelsey KT, Varkonyi A, Semey K, Wain JC, Mark E, Christiani DC. Correlation of DNA adducts in blood mononuclear cells with tobacco carcinogen-induced damage in human lung. Cancer Res. 1995 Nov 1; 55(21):4910-4.
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  133. Wang X, Christiani DC, Wiencke JK, Fischbein M, Xu X, Cheng TJ, Mark E, Wain JC, Kelsey KT. Mutations in the p53 gene in lung cancer are associated with cigarette smoking and asbestos exposure. Cancer Epidemiol Biomarkers Prev. 1995 Jul-Aug; 4(5):543-8.
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  134. Matsubara O, Tamura A, Ohdama S, Mark EJ. Alveolar basement membrane breaks down in diffuse alveolar damage: an immunohistochemical study. Pathol Int. 1995 Jul; 45(7):473-82.
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  135. Goulart RA, Mark EJ, Rosen S. Tumefactions as an extravascular manifestation of Wegener's granulomatosis. Am J Surg Pathol. 1995 Feb; 19(2):145-53.
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  136. Mark EJ, Muller KM, McChesney T, Dong-Hwan S, Honig C, Mark MA. Placentoid bullous lesion of the lung. Hum Pathol. 1995 Jan; 26(1):74-9.
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  137. Roggli VL, Hammar SP, Pratt PC, Maddox JC, Legier J, Mark EJ, Brody AR. Does asbestos or asbestosis cause carcinoma of the lung? Am J Ind Med. 1994 Dec; 26(6):835-8.
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  138. Bhalla M, Grillo HC, McLoud TC, Shepard JO, Weber AL, Mark EJ. Idiopathic laryngotracheal stenosis: radiologic findings. AJR Am J Roentgenol. 1993 Sep; 161(3):515-7.
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  139. Shin DH, Mark EJ, Suen HC, Grillo HC. Pathologic staging of papillary carcinoma of the thyroid with airway invasion based on the anatomic manner of extension to the trachea: a clinicopathologic study based on 22 patients who underwent thyroidectomy and airway resection. Hum Pathol. 1993 Aug; 24(8):866-70.
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  140. Grillo HC, Mark EJ, Mathisen DJ, Wain JC. Idiopathic laryngotracheal stenosis and its management. Ann Thorac Surg. 1993 Jul; 56(1):80-7.
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  141. Fienberg R, Mark EJ, Goodman M, McCluskey RT, Niles JL. Correlation of antineutrophil cytoplasmic antibodies with the extrarenal histopathology of Wegener's (pathergic) granulomatosis and related forms of vasculitis. Hum Pathol. 1993 Feb; 24(2):160-8.
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  142. Mark EJ, Shin DH. Diffuse malignant mesothelioma of the pleura: a clinicopathological study of six patients with a prolonged symptom-free interval or extended survival after biopsy and a review of the literature of long-term survival. Virchows Arch A Pathol Anat Histopathol. 1993; 422(6):445-51.
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  143. Fiel R, Mark E, Button T, Gilani S, Musser D. Tumor-selective contrast enhancing agent, Mn(III)meso- [tri(4-sulfonatophenyl)phenyl]porphine (MnTPPS3) Magn Reson Imaging. 1993; 11(7):1079-81.
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  144. Yoshimura N, Matsubara O, Tamura A, Kasuga T, Mark EJ. Wegener's granulomatosis. Associated with diffuse pulmonary hemorrhage. Acta Pathol Jpn. 1992 Sep; 42(9):657-61.
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  145. Mark EJ, Shin DH. Asbestos and the histogenesis of lung carcinoma. Semin Diagn Pathol. 1992 May; 9(2):110-6.
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  146. Schroeder SA, Shannon DC, Mark EJ. Cellular interstitial pneumonitis in infants. A clinicopathologic study. Chest. 1992 Apr; 101(4):1065-9.
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  147. Matsubara O, Yoshimura N, Tamura A, Kasuga T, Yamada I, Numano F, Mark EJ. Pathological features of the pulmonary artery in Takayasu arteritis. Heart Vessels Suppl. 1992; 7:18-25.
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  148. Mark EJ, Yokoi T. Absence of evidence for a significant background incidence of diffuse malignant mesothelioma apart from asbestos exposure. Ann N Y Acad Sci. 1991 Dec 31; 643:196-204.
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  149. Sunday ME, Choi N, Spindel ER, Chin WW, Mark EJ. Gastrin-releasing peptide gene expression in small cell and large cell undifferentiated lung carcinomas. Hum Pathol. 1991 Oct; 22(10):1030-9.
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  150. Yokoi T, Mark EJ. Atypical mesothelial hyperplasia associated with bronchogenic carcinoma. Hum Pathol. 1991 Jul; 22(7):695-9.
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  151. Bourgouin PM, McLoud TC, Fitzgibbon JF, Mark EJ, Shepard JA, Moore EM, Rummeny E, Brady TJ. Differentiation of bronchogenic carcinoma from postobstructive pneumonitis by magnetic resonance imaging: histopathologic correlation. J Thorac Imaging. 1991 Apr; 6(2):22-7.
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  152. Graeme-Cook F, Mark EJ. Pulmonary mucinous cystic tumors of borderline malignancy. Hum Pathol. 1991 Feb; 22(2):185-90.
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  153. Nakatani Y, Dickersin GR, Mark EJ. Pulmonary endodermal tumor resembling fetal lung: a clinicopathologic study of five cases with immunohistochemical and ultrastructural characterization. Hum Pathol. 1990 Nov; 21(11):1097-107.
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  154. Sherman ME, Mark EJ. Effusion cytology in the diagnosis of malignant epithelioid and biphasic pleural mesothelioma. Arch Pathol Lab Med. 1990 Aug; 114(8):845-51.
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  155. Mark EJ. An American pathologist's view of medicine on the island of Grenada. JAMA. 1989 May 5; 261(17):2553-4.
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  156. Heitmiller RF, Mathisen DJ, Ferry JA, Mark EJ, Grillo HC. Mucoepidermoid lung tumors. Ann Thorac Surg. 1989 Mar; 47(3):394-9.
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  157. Tan-Liu NS, Matsubara O, Grillo HC, Mark EJ. Invasive fibrous tumor of the tracheobronchial tree: clinical and pathologic study of seven cases. Hum Pathol. 1989 Feb; 20(2):180-4.
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  158. Rosenberg AE, Garber JE, Bennett W, Bhan AK, Antman KH, Mark EJ. Epithelioid sarcoma with diffuse bone marrow metastases and associated leukemoid reaction. A case report and brief literature review. Am J Clin Pathol. 1988 Dec; 90(6):723-6.
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  159. Mark EJ, Matsubara O, Tan-Liu NS, Fienberg R. The pulmonary biopsy in the early diagnosis of Wegener's (pathergic) granulomatosis: a study based on 35 open lung biopsies. Hum Pathol. 1988 Sep; 19(9):1065-71.
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  160. Matsubara O, Tan-Liu NS, Kenney RM, Mark EJ. Inflammatory pseudotumors of the lung: progression from organizing pneumonia to fibrous histiocytoma or to plasma cell granuloma in 32 cases. Hum Pathol. 1988 Jul; 19(7):807-14.
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  161. Vevaina JR, Mark EJ. Thoracic hemangiomatosis masquerading as interstitial lung disease. Chest. 1988 Mar; 93(3):657-9.
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  162. Garau X, Mark EJ. [A 37-year-old woman with cough and bilateral nodular picture on a chest x-ray (clinico-pathological conference)]. Med Clin (Barc). 1988 Jan 9; 90(1):33-9.
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  163. Mark EJ. Mesenchymal cystic hamartoma of the lung. N Engl J Med. 1986 Nov 13; 315(20):1255-9.
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  164. Schooley RT, Carey RW, Miller G, Henle W, Eastman R, Mark EJ, Kenyon K, Wheeler EO, Rubin RH. Chronic Epstein-Barr virus infection associated with fever and interstitial pneumonitis. Clinical and serologic features and response to antiviral chemotherapy. Ann Intern Med. 1986 May; 104(5):636-43.
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  165. Mark EJ, Ramirez JF. Pulmonary capillaritis and hemorrhage in patients with systemic vasculitis. Arch Pathol Lab Med. 1985 May; 109(5):413-8.
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  166. Kradin RL, Spirn PW, Mark EJ. Intrapulmonary lymph nodes. Clinical, radiologic, and pathologic features. Chest. 1985 May; 87(5):662-7.
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  167. Mark EJ, Ramirez JF. Peripheral small-cell carcinoma of the lung resembling carcinoid tumor. A clinical and pathologic study of 14 cases. Arch Pathol Lab Med. 1985 Mar; 109(3):263-9.
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  168. Duray PH, Mark EJ, Barwick KW, Madri JA, Strom RL. Congenital polycystic tumor of the atrioventricular node. Autopsy study with immunohistochemical findings suggesting endodermal derivation. Arch Pathol Lab Med. 1985 Jan; 109(1):30-4.
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  169. Antman KH, Nadler L, Mark EJ, Montella DL, Kirkpatrick P, Halpern J. Primary Kaposi's sarcoma of the lung in an immunocompetent 32-year-old heterosexual white man. Cancer. 1984 Oct 15; 54(8):1696-8.
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  170. Kradin RL, Mark EJ. Benign lymphoid disorders of the lung, with a theory regarding their development. Hum Pathol. 1983 Oct; 14(10):857-67.
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  171. Kradin RL, Young RH, Kradin LA, Mark EJ. Immunoblastic lymphoma arising in chronic lymphoid hyperplasia of the pulmonary interstitium. Cancer. 1982 Oct 1; 50(7):1339-43.
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  172. Hahn PF, Novelline RA, Mark EJ. Arteriography in the localization of massive pleural tumors. AJR Am J Roentgenol. 1982 Oct; 139(4):814-7.
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  173. Kradin RL, Young RH, Dickersin GR, Kirkham SE, Mark EJ. Pulmonary blastoma with argyrophil cells and lacking sarcomatous features (pulmonary endodermal tumor resembling fetal lung). Am J Surg Pathol. 1982 Mar; 6(2):165-72.
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  174. Kradin RL, Kiprov D, Dickersin GR, Collins AB, Kradin L, Mark EJ. Immune complex disease with fatal pulmonary hemorrhage: its occurrence in a patient with myasthenia gravis. Arch Pathol Lab Med. 1981 Nov; 105(11):582-5.
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  175. Mark EJ, Quay SC, Dickersin GR. Papillary carcinoid tumor of the lung. Cancer. 1981 Jul 15; 48(2):316-24.
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  176. Mark EJ. The second diagnosis: the role of the pathologist in identifying pneumoconioses in lungs excised for tumor. Hum Pathol. 1981 Jul; 12(7):585-7.
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  177. Briselli M, Mark EJ, Dickersin GR. Solitary fibrous tumors of the pleura: eight new cases and review of 360 cases in the literature. Cancer. 1981 Jun 1; 47(11):2678-89.
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