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Amitinder Kaur, M.D.

TitleAssociate Professor of Medicine
InstitutionHarvard Medical School
DepartmentMedicine
AddressN.E. Reg. Primate Research Ctr
Immunology
1 Pine Hill Dr
Southborough MA 01772
Phone508/624-8169
Fax508/624-8172

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Martinot AJ, Meythaler M, Pozzi LA, Dalecki Boisvert K, Knight H, Walsh D, Westmoreland S, Anderson DC, Kaur A, O'Neil SP. Acute SIV Infection in Sooty Mangabey Monkeys Is Characterized by Rapid Virus Clearance from Lymph Nodes and Absence of Productive Infection in Germinal Centers. PLoS One. 2013; 8(3):e57785.
    View in: PubMed
  2. Rout N, Greene J, Yue S, O'Connor D, Johnson RP, Else JG, Exley MA, Kaur A. Loss of effector and anti-inflammatory natural killer T lymphocyte function in pathogenic simian immunodeficiency virus infection. PLoS Pathog. 2012 Sep; 8(9):e1002928.
    View in: PubMed
  3. Assaf BT, Mansfield KG, Westmoreland SV, Kaur A, Oxford KL, Diamond DJ, Barry PA. Patterns of acute rhesus cytomegalovirus (RhCMV) infection predict long-term RhCMV infection. J Virol. 2012 Jun; 86(11):6354-7.
    View in: PubMed
  4. Meythaler M, Wang Z, Martinot A, Pryputniewicz S, Kasheta M, McClure HM, O'Neil SP, Kaur A. Early induction of polyfunctional simian immunodeficiency virus (SIV)-specific T lymphocytes and rapid disappearance of SIV from lymph nodes of sooty mangabeys during primary infection. J Immunol. 2011 May 1; 186(9):5151-61.
    View in: PubMed
  5. Elemans M, ThiƩbaut R, Kaur A, Asquith B. Quantification of the relative importance of CTL, B cell, NK cell, and target cell limitation in the control of primary SIV-infection. PLoS Comput Biol. 2011 Mar; 7(3):e1001103.
    View in: PubMed
  6. Kirmaier A, Wu F, Newman RM, Hall LR, Morgan JS, O'Connor S, Marx PA, Meythaler M, Goldstein S, Buckler-White A, Kaur A, Hirsch VM, Johnson WE. TRIM5 suppresses cross-species transmission of a primate immunodeficiency virus and selects for emergence of resistant variants in the new species. PLoS Biol. 2010; 8(8).
    View in: PubMed
  7. Rout N, Else JG, Yue S, Connole M, Exley MA, Kaur A. Heterogeneity in phenotype and function of CD8+ and CD4/CD8 double-negative Natural Killer T cell subsets in sooty mangabeys. J Med Primatol. 2010 Aug; 39(4):224-34.
    View in: PubMed
  8. Rout N, Else JG, Yue S, Connole M, Exley MA, Kaur A. Paucity of CD4+ natural killer T (NKT) lymphocytes in sooty mangabeys is associated with lack of NKT cell depletion after SIV infection. PLoS One. 2010; 5(3):e9787.
    View in: PubMed
  9. Zahn RC, Rett MD, Li M, Tang H, Korioth-Schmitz B, Balachandran H, White R, Pryputniewicz S, Letvin NL, Kaur A, Montefiori DC, Carville A, Hirsch VM, Allan JS, Schmitz JE. Suppression of adaptive immune responses during primary SIV infection of sabaeus African green monkeys delays partial containment of viremia but does not induce disease. Blood. 2010 Apr 15; 115(15):3070-8.
    View in: PubMed
  10. Schmitz JE, Zahn RC, Brown CR, Rett MD, Li M, Tang H, Pryputniewicz S, Byrum RA, Kaur A, Montefiori DC, Allan JS, Goldstein S, Hirsch VM. Inhibition of adaptive immune responses leads to a fatal clinical outcome in SIV-infected pigtailed macaques but not vervet African green monkeys. PLoS Pathog. 2009 Dec; 5(12):e1000691.
    View in: PubMed
  11. Sodora DL, Allan JS, Apetrei C, Brenchley JM, Douek DC, Else JG, Estes JD, Hahn BH, Hirsch VM, Kaur A, Kirchhoff F, Muller-Trutwin M, Pandrea I, Schmitz JE, Silvestri G. Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts. Nat Med. 2009 Aug; 15(8):861-5.
    View in: PubMed
  12. Gaufin T, Gautam R, Kasheta M, Ribeiro R, Ribka E, Barnes M, Pattison M, Tatum C, MacFarland J, Montefiori D, Kaur A, Pandrea I, Apetrei C. Limited ability of humoral immune responses in control of viremia during infection with SIVsmmD215 strain. Blood. 2009 Apr 30; 113(18):4250-61.
    View in: PubMed
  13. Meythaler M, Pryputniewicz S, Kaur A. Kinetics of T lymphocyte apoptosis and the cellular immune response in SIVmac239-infected rhesus macaques. J Med Primatol. 2008 Dec; 37 Suppl 2:33-45.
    View in: PubMed
  14. Meythaler M, Martinot A, Wang Z, Pryputniewicz S, Kasheta M, Ling B, Marx PA, O'Neil S, Kaur A. Differential CD4+ T-lymphocyte apoptosis and bystander T-cell activation in rhesus macaques and sooty mangabeys during acute simian immunodeficiency virus infection. J Virol. 2009 Jan; 83(2):572-83.
    View in: PubMed
  15. Gordon SN, Dunham RM, Engram JC, Estes J, Wang Z, Klatt NR, Paiardini M, Pandrea IV, Apetrei C, Sodora DL, Lee HY, Haase AT, Miller MD, Kaur A, Staprans SI, Perelson AS, Feinberg MB, Silvestri G. Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis. J Virol. 2008 Apr; 82(7):3725-35.
    View in: PubMed
  16. DeGottardi MQ, Specht A, Metcalf B, Kaur A, Kirchhoff F, Evans DT. Selective downregulation of rhesus macaque and sooty mangabey major histocompatibility complex class I molecules by Nef alleles of simian immunodeficiency virus and human immunodeficiency virus type 2. J Virol. 2008 Mar; 82(6):3139-46.
    View in: PubMed
  17. Kaur A, Di Mascio M, Barabasz A, Rosenzweig M, McClure HM, Perelson AS, Ribeiro RM, Johnson RP. Dynamics of T- and B-lymphocyte turnover in a natural host of simian immunodeficiency virus. J Virol. 2008 Feb; 82(3):1084-93.
    View in: PubMed
  18. Chan KS, Kaur A. Flow cytometric detection of degranulation reveals phenotypic heterogeneity of degranulating CMV-specific CD8+ T lymphocytes in rhesus macaques. J Immunol Methods. 2007 Aug 31; 325(1-2):20-34.
    View in: PubMed
  19. Newman RM, Hall L, Connole M, Chen GL, Sato S, Yuste E, Diehl W, Hunter E, Kaur A, Miller GM, Johnson WE. Balancing selection and the evolution of functional polymorphism in Old World monkey TRIM5alpha. Proc Natl Acad Sci U S A. 2006 Dec 12; 103(50):19134-9.
    View in: PubMed
  20. Yue Y, Kaur A, Eberhardt MK, Kassis N, Zhou SS, Tarantal AF, Barry PA. Immunogenicity and protective efficacy of DNA vaccines expressing rhesus cytomegalovirus glycoprotein B, phosphoprotein 65-2, and viral interleukin-10 in rhesus macaques. J Virol. 2007 Feb; 81(3):1095-109.
    View in: PubMed
  21. Pandrea I, Apetrei C, Gordon S, Barbercheck J, Dufour J, Bohm R, Sumpter B, Roques P, Marx PA, Hirsch VM, Kaur A, Lackner AA, Veazey RS, Silvestri G. Paucity of CD4+CCR5+ T cells is a typical feature of natural SIV hosts. Blood. 2007 Feb 1; 109(3):1069-76.
    View in: PubMed
  22. Kaur A, Sanford HB, Garry D, Lang S, Klumpp SA, Watanabe D, Bronson RT, Lifson JD, Rosati M, Pavlakis GN, Felber BK, Knipe DM, Desrosiers RC. Ability of herpes simplex virus vectors to boost immune responses to DNA vectors and to protect against challenge by simian immunodeficiency virus. Virology. 2007 Jan 20; 357(2):199-214.
    View in: PubMed
  23. Macchia I, Gauduin MC, Kaur A, Johnson RP. Expression of CD8alpha identifies a distinct subset of effector memory CD4+ T lymphocytes. Immunology. 2006 Oct; 119(2):232-42.
    View in: PubMed
  24. Rivailler P, Kaur A, Johnson RP, Wang F. Genomic sequence of rhesus cytomegalovirus 180.92: insights into the coding potential of rhesus cytomegalovirus. J Virol. 2006 Apr; 80(8):4179-82.
    View in: PubMed
  25. Yue Y, Kaur A, Zhou SS, Barry PA. Characterization and immunological analysis of the rhesus cytomegalovirus homologue (Rh112) of the human cytomegalovirus UL83 lower matrix phosphoprotein (pp65). J Gen Virol. 2006 Apr; 87(Pt 4):777-87.
    View in: PubMed
  26. Fogg MH, Garry D, Awad A, Wang F, Kaur A. The BZLF1 homolog of an Epstein-Barr-related gamma-herpesvirus is a frequent target of the CTL response in persistently infected rhesus macaques. J Immunol. 2006 Mar 15; 176(6):3391-401.
    View in: PubMed
  27. Wang Z, Metcalf B, Ribeiro RM, McClure H, Kaur A. Th-1-type cytotoxic CD8+ T-lymphocyte responses to simian immunodeficiency virus (SIV) are a consistent feature of natural SIV infection in sooty mangabeys. J Virol. 2006 Mar; 80(6):2771-83.
    View in: PubMed
  28. Apetrei C, Lerche NW, Pandrea I, Gormus B, Silvestri G, Kaur A, Robertson DL, Hardcastle J, Lackner AA, Marx PA. Kuru experiments triggered the emergence of pathogenic SIVmac. AIDS. 2006 Feb 14; 20(3):317-21.
    View in: PubMed
  29. Fogg MH, Kaur A, Cho YG, Wang F. The CD8+ T-cell response to an Epstein-Barr virus-related gammaherpesvirus infecting rhesus macaques provides evidence for immune evasion by the EBNA-1 homologue. J Virol. 2005 Oct; 79(20):12681-91.
    View in: PubMed
  30. Woodberry T, Suscovich TJ, Henry LM, August M, Waring MT, Kaur A, Hess C, Kutok JL, Aster JC, Wang F, Scadden DT, Brander C. Alpha E beta 7 (CD103) expression identifies a highly active, tonsil-resident effector-memory CTL population. J Immunol. 2005 Oct 1; 175(7):4355-62.
    View in: PubMed
  31. Apetrei C, Kaur A, Lerche NW, Metzger M, Pandrea I, Hardcastle J, Falkenstein S, Bohm R, Koehler J, Traina-Dorge V, Williams T, Staprans S, Plauche G, Veazey RS, McClure H, Lackner AA, Gormus B, Robertson DL, Marx PA. Molecular epidemiology of simian immunodeficiency virus SIVsm in U.S. primate centers unravels the origin of SIVmac and SIVstm. J Virol. 2005 Jul; 79(14):8991-9005.
    View in: PubMed
  32. Cohen GB, Kaur A, Johnson RP. Isolation of viable antigen-specific CD4 T cells by CD40L surface trapping. J Immunol Methods. 2005 Jul; 302(1-2):103-15.
    View in: PubMed
  33. Johnson RP, Kaur A. HIV: viral blitzkrieg. Nature. 2005 Apr 28; 434(7037):1080-1.
    View in: PubMed
  34. Elkington R, Shoukry NH, Walker S, Crough T, Fazou C, Kaur A, Walker CM, Khanna R. Cross-reactive recognition of human and primate cytomegalovirus sequences by human CD4 cytotoxic T lymphocytes specific for glycoprotein B and H. Eur J Immunol. 2004 Nov; 34(11):3216-26.
    View in: PubMed
  35. Rivailler P, Carville A, Kaur A, Rao P, Quink C, Kutok JL, Westmoreland S, Klumpp S, Simon M, Aster JC, Wang F. Experimental rhesus lymphocryptovirus infection in immunosuppressed macaques: an animal model for Epstein-Barr virus pathogenesis in the immunosuppressed host. Blood. 2004 Sep 1; 104(5):1482-9.
    View in: PubMed
  36. Gauduin MC, Kaur A, Ahmad S, Yilma T, Lifson JD, Johnson RP. Optimization of intracellular cytokine staining for the quantitation of antigen-specific CD4+ T cell responses in rhesus macaques. J Immunol Methods. 2004 May; 288(1-2):61-79.
    View in: PubMed
  37. Mueller NJ, Sulling K, Gollackner B, Yamamoto S, Knosalla C, Wilkinson RA, Kaur A, Sachs DH, Yamada K, Cooper DK, Patience C, Fishman JA. Reduced efficacy of ganciclovir against porcine and baboon cytomegalovirus in pig-to-baboon xenotransplantation. Am J Transplant. 2003 Sep; 3(9):1057-64.
    View in: PubMed
  38. Kaur A, Johnson RP. HIV pathogenesis and vaccine development. Top HIV Med. 2003 May-Jun; 11(3):76-85.
    View in: PubMed
  39. Kaur A, Kassis N, Hale CL, Simon M, Elliott M, Gomez-Yafal A, Lifson JD, Desrosiers RC, Wang F, Barry P, Mach M, Johnson RP. Direct relationship between suppression of virus-specific immunity and emergence of cytomegalovirus disease in simian AIDS. J Virol. 2003 May; 77(10):5749-58.
    View in: PubMed
  40. Mueller NJ, Barth RN, Yamamoto S, Kitamura H, Patience C, Yamada K, Cooper DK, Sachs DH, Kaur A, Fishman JA. Activation of cytomegalovirus in pig-to-primate organ xenotransplantation. J Virol. 2002 May; 76(10):4734-40.
    View in: PubMed
  41. Kaur A, Hale CL, Noren B, Kassis N, Simon MA, Johnson RP. Decreased frequency of cytomegalovirus (CMV)-specific CD4+ T lymphocytes in simian immunodeficiency virus-infected rhesus macaques: inverse relationship with CMV viremia. J Virol. 2002 Apr; 76(8):3646-58.
    View in: PubMed
  42. Kaur A, Alexander L, Staprans SI, Denekamp L, Hale CL, McClure HM, Feinberg MB, Desrosiers RC, Johnson RP. Emergence of cytotoxic T lymphocyte escape mutations in nonpathogenic simian immunodeficiency virus infection. Eur J Immunol. 2001 Nov; 31(11):3207-17.
    View in: PubMed
  43. Kaur A, Hale CL, Ramanujan S, Jain RK, Johnson RP. Differential dynamics of CD4(+) and CD8(+) T-lymphocyte proliferation and activation in acute simian immunodeficiency virus infection. J Virol. 2000 Sep; 74(18):8413-24.
    View in: PubMed
  44. Kaur A, Yang J, Hempel D, Gritz L, Mazzara GP, McClure H, Johnson RP. Identification of multiple simian immunodeficiency virus (SIV)-specific CTL epitopes in sooty mangabeys with natural and experimentally acquired SIV infection. J Immunol. 2000 Jan 15; 164(2):934-43.
    View in: PubMed
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