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Paola Arlotta, Ph.D.

TitleAssistant Professor of Surgery
InstitutionMassachusetts General Hospital
DepartmentSurgery
AddressArlotta Lab, 3rd Floor
Sherman Fairchild Biochemistry Bldg
7 Divinity Ave
Cambridge MA 02138
Phone617/496-9810
Fax617/724-2662

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Tomassy GS, Lodato S, Arlotta P. A Sip of GABA for the Cerebral Cortex. Neuron. 2013 Jan 9; 77(1):1-3.
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  2. Rouaux C, Arlotta P. Direct lineage reprogramming of post-mitotic callosal neurons into corticofugal neurons in vivo. Nat Cell Biol. 2012 Dec 23; 15(2):214-21.
    View in: PubMed
  3. Rouaux C, Bhai S, Arlotta P. Programming and reprogramming neuronal subtypes in the central nervous system. Dev Neurobiol. 2012 Jul; 72(7):1085-98.
    View in: PubMed
  4. Cappello S, Böhringer CR, Bergami M, Conzelmann KK, Ghanem A, Tomassy GS, Arlotta P, Mainardi M, Allegra M, Caleo M, van Hengel J, Brakebusch C, Götz M. A radial glia-specific role of RhoA in double cortex formation. Neuron. 2012 Mar 8; 73(5):911-24.
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  5. Sohur US, Arlotta P, Macklis JD. Developmental Controls are Re-Expressed during Induction of Neurogenesis in the Neocortex of Young Adult Mice. Front Neurosci. 2012; 6:12.
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  6. López-Bendito G, Arlotta P. Cell replacement therapies for nervous system regeneration. Dev Neurobiol. 2012 Feb; 72(2):145-52.
    View in: PubMed
  7. Lodato S, Tomassy GS, De Leonibus E, Uzcategui YG, Andolfi G, Armentano M, Touzot A, Gaztelu JM, Arlotta P, Menendez de la Prida L, Studer M. Loss of COUP-TFI alters the balance between caudal ganglionic eminence- and medial ganglionic eminence-derived cortical interneurons and results in resistance to epilepsy. J Neurosci. 2011 Mar 23; 31(12):4650-62.
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  8. Lodato S, Rouaux C, Quast KB, Jantrachotechatchawan C, Studer M, Hensch TK, Arlotta P. Excitatory projection neuron subtypes control the distribution of local inhibitory interneurons in the cerebral cortex. Neuron. 2011 Feb 24; 69(4):763-79.
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  9. Zhang F, Cong L, Lodato S, Kosuri S, Church GM, Arlotta P. Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription. Nat Biotechnol. 2011 Feb; 29(2):149-53.
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  10. Rouaux C, Arlotta P. Fezf2 directs the differentiation of corticofugal neurons from striatal progenitors in vivo. Nat Neurosci. 2010 Nov; 13(11):1345-7.
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  11. Shoemaker LD, Arlotta P. Untangling the cortex: Advances in understanding specification and differentiation of corticospinal motor neurons. Bioessays. 2010 Mar; 32(3):197-206.
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  12. Tomassy GS, Lodato S, Trayes-Gibson Z, Arlotta P. Development and regeneration of projection neuron subtypes of the cerebral cortex. Sci Prog. 2010; 93(Pt 2):151-69.
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  13. Molyneaux BJ, Arlotta P, Fame RM, MacDonald JL, MacQuarrie KL, Macklis JD. Novel subtype-specific genes identify distinct subpopulations of callosal projection neurons. J Neurosci. 2009 Sep 30; 29(39):12343-54.
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  14. Lai T, Jabaudon D, Molyneaux BJ, Azim E, Arlotta P, Menezes JR, Macklis JD. SOX5 controls the sequential generation of distinct corticofugal neuron subtypes. Neuron. 2008 Jan 24; 57(2):232-47.
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  15. Arlotta P, Molyneaux BJ, Jabaudon D, Yoshida Y, Macklis JD. Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum. J Neurosci. 2008 Jan 16; 28(3):622-32.
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  16. Gao X, Arlotta P, Macklis JD, Chen J. Conditional knock-out of beta-catenin in postnatal-born dentate gyrus granule neurons results in dendritic malformation. J Neurosci. 2007 Dec 26; 27(52):14317-25.
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  17. Molyneaux BJ, Arlotta P, Menezes JR, Macklis JD. Neuronal subtype specification in the cerebral cortex. Nat Rev Neurosci. 2007 Jun; 8(6):427-37.
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  18. Molyneaux BJ, Arlotta P, Macklis JD. Molecular development of corticospinal motor neuron circuitry. Novartis Found Symp. 2007; 288:3-15; discussion 15-20, 96-8.
    View in: PubMed
  19. Molyneaux BJ, Arlotta P, Hirata T, Hibi M, Macklis JD. Fezl is required for the birth and specification of corticospinal motor neurons. Neuron. 2005 Sep 15; 47(6):817-31.
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  20. Arlotta P, Macklis JD. Archeo-cell biology: carbon dating is not just for pots and dinosaurs. Cell. 2005 Jul 15; 122(1):4-6.
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  21. Arlotta P, Molyneaux BJ, Chen J, Inoue J, Kominami R, Macklis JD. Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo. Neuron. 2005 Jan 20; 45(2):207-21.
    View in: PubMed
  22. Emsley JG, Mitchell BD, Magavi SS, Arlotta P, Macklis JD. The repair of complex neuronal circuitry by transplanted and endogenous precursors. NeuroRx. 2004 Oct; 1(4):452-71.
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  23. Emsley JG, Arlotta P, Macklis JD. Star-cross'd neurons: astroglial effects on neural repair in the adult mammalian CNS. Trends Neurosci. 2004 May; 27(5):238-40.
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  24. Catapano LA, Arlotta P, Cage TA, Macklis JD. Stage-specific and opposing roles of BDNF, NT-3 and bFGF in differentiation of purified callosal projection neurons toward cellular repair of complex circuitry. Eur J Neurosci. 2004 May; 19(9):2421-34.
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  25. Mitchell BD, Emsley JG, Magavi SS, Arlotta P, Macklis JD. Constitutive and induced neurogenesis in the adult mammalian brain: manipulation of endogenous precursors toward CNS repair. Dev Neurosci. 2004 Mar-Aug; 26(2-4):101-17.
    View in: PubMed
  26. Arlotta P, Magavi SS, Macklis JD. Induction of adult neurogenesis: molecular manipulation of neural precursors in situ. Ann N Y Acad Sci. 2003 Jun; 991:229-36.
    View in: PubMed
  27. Arlotta P, Magavi SS, Macklis JD. Molecular manipulation of neural precursors in situ: induction of adult cortical neurogenesis. Exp Gerontol. 2003 Jan-Feb; 38(1-2):173-82.
    View in: PubMed
  28. Arlotta P, Miyazaki D, Copeland NG, Gilbert DJ, Jenkins NA, Ono SJ. Murine NFX.1: isolation and characterization of its messenger RNA, mapping of its chromosomal location and assessment of its developmental expression. Immunology. 2002 Jun; 106(2):173-81.
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  29. Liu F, Chau KY, Arlotta P, Ono SJ. The HMG I proteins: dynamic roles in gene activation, development, and tumorigenesis. Immunol Res. 2001; 24(1):13-29.
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  30. Fedoseyeva EV, Boisgérault F, Anosova NG, Wollish WS, Arlotta P, Jensen PE, Ono SJ, Benichou G. CD4+ T cell responses to self- and mutated p53 determinants during tumorigenesis in mice. J Immunol. 2000 Jun 1; 164(11):5641-51.
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  31. Arlotta P, Tai AK, Manfioletti G, Clifford C, Jay G, Ono SJ. Transgenic mice expressing a truncated form of the high mobility group I-C protein develop adiposity and an abnormally high prevalence of lipomas. J Biol Chem. 2000 May 12; 275(19):14394-400.
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  32. Chau K, Arlotta P, Patel UA, Crane-Robinson C, Manfioletti G, Ono SJ. A novel downstream positive regulatory element mediating transcription of the human high mobility group (HMG) I-C gene. FEBS Lett. 1999 Sep 3; 457(3):429-36.
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  33. Arlotta P, Rustighi A, Mantovani F, Manfioletti G, Giancotti V, Tell G, Damante G. High mobility group I proteins interfere with the homeodomains binding to DNA. J Biol Chem. 1997 Nov 21; 272(47):29904-10.
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  34. Arlotta P, Curci G, Perazzoli CA, Santori L. [Reconstruction of severe loss of mandibular bone substance using metal prostheses]. Minerva Stomatol. 1980 Nov-Dec; 29(6):515-26.
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  35. Arlotta P, Santori L, de Vecchi A. [A case of mixed tumor of the palate]. Acta Biol Med Ger. 1976 Jul-Sep; 2(3):34.
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  36. Arlotta P, Tassarotti B, Santori L. [Surgical therapy of submandibular sialolithiasis]. Odontostomatol Implantoprotesi. 1975 Jan-Mar; (1):78-81.
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  37. Arlotta P, Curci G, Morelli-Coghi A, Pizzoni D. [Treatment of fracture of the zygomatic arch by means of metallic osteosynthesis]. Rass Int Stomatol Prat. 1972 Nov-Dec; 23(6):189-203.
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  38. Arlotta P, Silla M. [Solitary plasmacytoma of the mandible]. Rass Int Stomatol Prat. 1972 Sep-Oct; 23(5):153-61.
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  39. Grampa G, Bestetti-Bosisio M, Bergamini F, Arlotta P. A case of Burkitt's tumor in Italy. Pathol Eur. 1970; 5(4):470-84.
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  40. Arlotta P, Pizzoni D. Fractures of the zygomatic complex. Br J Oral Surg. 1967 Mar; 4(3):192-3.
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  41. ARLOTTA P, TALAMAZZI F. [Clinico-statistical study of tumors of the upper jaw]. Riv Ital Stomatol. 1954 May; 9(5):539-50.
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  42. ARLOTTA P. [Transalveolar route in novocaine analgesia with gelatin sponge in periodontitis]. Minerva Stomatol. 1953 May-Jun; 2(3):141-3.
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  43. ARLOTTA P. [Xylocaine in use at the Milan Dental Clinic]. Riv Ital Stomatol. 1951 Nov; 6(11):1187-91.
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  44. ARLOTTA P. [Trichloroethylene in dentin hyperesthesia]. Riv Ital Stomatol. 1951 Sep; 6(9):916-20.
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  45. ARLOTTA P. [Gingival hyperplasia due to sodium diphenylhydantoinate]. Riv Ital Stomatol. 1951 Feb; 6(2):180-7.
    View in: PubMed
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