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Sei Kwang Hahn, Ph.D.

TitleVisiting Associate Professor of Dermatology
InstitutionMassachusetts General Hospital
DepartmentDermatology
AddressPartners Research Building
Wellman Center for Photomedicine
65 Landsdowne St
Cambridge MA 02139
Phone6177688715

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Lee MY, Yang JA, Jung HS, Beack S, Choi JE, Hur W, Koo H, Kim K, Yoon SK, Hahn SK. Hyaluronic Acid-Gold Nanoparticle/Interferon a Complex for Targeted Treatment of Hepatitis C Virus Infection. ACS Nano. 2012 Nov 27; 6(11):9522-31.
    View in: PubMed
  2. Sung DK, Kong WH, Park K, Kim JH, Kim MY, Kim H, Hahn SK. Noncovalenly PEGylated CTGF siRNA/PDMAEMA complex for pulmonary treatment of bleomycin-induced lung fibrosis. Biomaterials. 2013 Jan; 34(4):1261-9.
    View in: PubMed
  3. Kong WH, Park K, Lee MY, Lee H, Sung DK, Hahn SK. Cationic solid lipid nanoparticles derived from apolipoprotein-free LDLs for target specific systemic treatment of liver fibrosis. Biomaterials. 2013 Jan; 34(2):542-51.
    View in: PubMed
  4. Koo H, Lee S, Na JH, Kim SH, Hahn SK, Choi K, Kwon IC, Jeong SY, Kim K. Bioorthogonal copper-free click chemistry in vivo for tumor-targeted delivery of nanoparticles. Angew Chem Int Ed Engl. 2012 Nov 19; 51(47):11836-40.
    View in: PubMed
  5. Goh EJ, Kim KS, Kim YR, Jung HS, Beack S, Kong WH, Scarcelli G, Yun SH, Hahn SK. Bioimaging of hyaluronic acid derivatives using nanosized carbon dots. Biomacromolecules. 2012 Aug 13; 13(8):2554-61.
    View in: PubMed
  6. Kim H, Choi JS, Kim KS, Yang JA, Joo CK, Hahn SK. Flt1 peptide-hyaluronate conjugate micelle-like nanoparticles encapsulating genistein for the treatment of ocular neovascularization. Acta Biomater. 2012 Nov; 8(11):3932-40.
    View in: PubMed
  7. Kong WH, Sung DK, Kim KS, Jung HS, Gho EJ, Yun SH, Hahn SK. Self-assembled complex of probe peptide--E. Coli RNA I conjugate and nano graphene oxide for apoptosis diagnosis. Biomaterials. 2012 Oct; 33(30):7556-64.
    View in: PubMed
  8. Kim KS, Kim S, Beack S, Yang JA, Yun SH, Hahn SK. In vivo real-time confocal microscopy for target-specific delivery of hyaluronic acid-quantum dot conjugates. Nanomedicine. 2012 Oct; 8(7):1070-3.
    View in: PubMed
  9. Yang JA, Kim ES, Kwon JH, Kim H, Shin JH, Yun SH, Choi KY, Hahn SK. Transdermal delivery of hyaluronic acid -- human growth hormone conjugate. Biomaterials. 2012 Sep; 33(25):5947-54.
    View in: PubMed
  10. Park KM, Yang JA, Jung H, Yeom J, Park JS, Park KH, Hoffman AS, Hahn SK, Kim K. In situ supramolecular assembly and modular modification of hyaluronic acid hydrogels for 3D cellular engineering. ACS Nano. 2012 Apr 24; 6(4):2960-8.
    View in: PubMed
  11. Kong WH, Bae KH, Hong CA, Lee Y, Hahn SK, Park TG. Multimerized siRNA cross-linked by gold nanoparticles. Bioconjug Chem. 2011 Oct 19; 22(10):1962-9.
    View in: PubMed
  12. Yang JA, Park K, Jung H, Kim H, Hong SW, Yoon SK, Hahn SK. Target specific hyaluronic acid-interferon alpha conjugate for the treatment of hepatitis C virus infection. Biomaterials. 2011 Nov; 32(33):8722-9.
    View in: PubMed
  13. Jung H, Park KM, Yang JA, Oh EJ, Lee DW, Park K, Ryu SH, Hahn SK, Kim K. Theranostic systems assembled in situ on demand by host-guest chemistry. Biomaterials. 2011 Oct; 32(30):7687-94.
    View in: PubMed
  14. Lee MY, Park SJ, Park K, Kim KS, Lee H, Hahn SK. Target-specific gene silencing of layer-by-layer assembled gold-cysteamine/siRNA/PEI/HA nanocomplex. ACS Nano. 2011 Aug 23; 5(8):6138-47.
    View in: PubMed
  15. Yan XM, Seo MS, Hwang EJ, Cho IH, Hahn SK, Sohn UD. Improved synthesis of hyaluronic acid hydrogel and its effect on tissue augmentation. J Biomater Appl. 2012 Aug; 27(2):179-86.
    View in: PubMed
  16. Park K, Hong SW, Hur W, Lee MY, Yang JA, Kim SW, Yoon SK, Hahn SK. Target specific systemic delivery of TGF-ß siRNA/(PEI-SS)-g-HA complex for the treatment of liver cirrhosis. Biomaterials. 2011 Jul; 32(21):4951-8.
    View in: PubMed
  17. Oh EJ, Choi JS, Kim H, Joo CK, Hahn SK. Anti-Flt1 peptide - hyaluronate conjugate for the treatment of retinal neovascularization and diabetic retinopathy. Biomaterials. 2011 Apr; 32(11):3115-23.
    View in: PubMed
  18. Park JK, Kim YJ, Yeom J, Jeon JH, Yi GC, Je JH, Hahn SK. The topographic effect of zinc oxide nanoflowers on osteoblast growth and osseointegration. Adv Mater. 2010 Nov 16; 22(43):4857-61.
    View in: PubMed
  19. Yeom J, Chang S, Park JK, Je JH, Yang DJ, Choi SK, Shin HI, Lee SJ, Shim JH, Cho DW, Hahn SK. Synchrotron X-ray bioimaging of bone regeneration by artificial bone substitute of MegaGen Synthetic Bone and hyaluronate hydrogels. Tissue Eng Part C Methods. 2010 Oct; 16(5):1059-68.
    View in: PubMed
  20. Kim KS, Park SJ, Yang JA, Jeon JH, Bhang SH, Kim BS, Hahn SK. Injectable hyaluronic acid-tyramine hydrogels for the treatment of rheumatoid arthritis. Acta Biomater. 2011 Feb; 7(2):666-74.
    View in: PubMed
  21. Yang SY, Yang JA, Kim ES, Jeon G, Oh EJ, Choi KY, Hahn SK, Kim JK. Single-file diffusion of protein drugs through cylindrical nanochannels. ACS Nano. 2010 Jul 27; 4(7):3817-22.
    View in: PubMed
  22. An T, Kim KS, Hahn SK, Lim G. Real-time, step-wise, electrical detection of protein molecules using dielectrophoretically aligned SWNT-film FET aptasensors. Lab Chip. 2010 Aug 21; 10(16):2052-6.
    View in: PubMed
  23. Kim KS, Hur W, Park SJ, Hong SW, Choi JE, Goh EJ, Yoon SK, Hahn SK. Bioimaging for targeted delivery of hyaluronic Acid derivatives to the livers in cirrhotic mice using quantum dots. ACS Nano. 2010 Jun 22; 4(6):3005-14.
    View in: PubMed
  24. Park K, Lee MY, Kim KS, Hahn SK. Target specific tumor treatment by VEGF siRNA complexed with reducible polyethyleneimine-hyaluronic acid conjugate. Biomaterials. 2010 Jul; 31(19):5258-65.
    View in: PubMed
  25. Yeom J, Bhang SH, Kim BS, Seo MS, Hwang EJ, Cho IH, Park JK, Hahn SK. Effect of cross-linking reagents for hyaluronic acid hydrogel dermal fillers on tissue augmentation and regeneration. Bioconjug Chem. 2010 Feb 17; 21(2):240-7.
    View in: PubMed
  26. Kong JH, Oh EJ, Chae SY, Lee KC, Hahn SK. Long acting hyaluronate--exendin 4 conjugate for the treatment of type 2 diabetes. Biomaterials. 2010 May; 31(14):4121-8.
    View in: PubMed
  27. Shim JH, Kim JY, Park JK, Hahn SK, Rhie JW, Kang SW, Lee SH, Cho DW. Effect of thermal degradation of SFF-based PLGA scaffolds fabricated using a multi-head deposition system followed by change of cell growth rate. J Biomater Sci Polym Ed. 2010; 21(8-9):1069-80.
    View in: PubMed
  28. Oh EJ, Park K, Kim KS, Kim J, Yang JA, Kong JH, Lee MY, Hoffman AS, Hahn SK. Target specific and long-acting delivery of protein, peptide, and nucleotide therapeutics using hyaluronic acid derivatives. J Control Release. 2010 Jan 4; 141(1):2-12.
    View in: PubMed
  29. Oh EJ, Park K, Choi JS, Joo CK, Hahn SK. Synthesis, characterization, and preliminary assessment of anti-Flt1 peptide-hyaluronate conjugate for the treatment of corneal neovascularization. Biomaterials. 2009 Oct; 30(30):6026-34.
    View in: PubMed
  30. Bhang SH, Won N, Lee TJ, Jin H, Nam J, Park J, Chung H, Park HS, Sung YE, Hahn SK, Kim BS, Kim S. Hyaluronic acid-quantum dot conjugates for in vivo lymphatic vessel imaging. ACS Nano. 2009 Jun 23; 3(6):1389-98.
    View in: PubMed
  31. Park JK, Yeom J, Oh EJ, Reddy M, Kim JY, Cho DW, Lim HP, Kim NS, Park SW, Shin HI, Yang DJ, Park KB, Hahn SK. Guided bone regeneration by poly(lactic-co-glycolic acid) grafted hyaluronic acid bi-layer films for periodontal barrier applications. Acta Biomater. 2009 Nov; 5(9):3394-403.
    View in: PubMed
  32. Kim KS, Lee HS, Yang JA, Jo MH, Hahn SK. The fabrication, characterization and application of aptamer-functionalized Si-nanowire FET biosensors. Nanotechnology. 2009 Jun 10; 20(23):235501.
    View in: PubMed
  33. Jiang G, Park K, Kim J, Kim KS, Hahn SK. Target specific intracellular delivery of siRNA/PEI-HA complex by receptor mediated endocytosis. Mol Pharm. 2009 May-Jun; 6(3):727-37.
    View in: PubMed
  34. Han SE, Kang H, Shim GY, Kim SJ, Choi HG, Kim J, Hahn SK, Oh YK. Cationic derivatives of biocompatible hyaluronic acids for delivery of siRNA and antisense oligonucleotides. J Drug Target. 2009 Feb; 17(2):123-32.
    View in: PubMed
  35. Kim J, Kim KS, Jiang G, Kang H, Kim S, Kim BS, Park MH, Hahn SK. In vivo real-time bioimaging of hyaluronic acid derivatives using quantum dots. Biopolymers. 2008 Dec; 89(12):1144-53.
    View in: PubMed
  36. Oh EJ, Kim JW, Kong JH, Ryu SH, Hahn SK. Signal transduction of hyaluronic acid-peptide conjugate for formyl peptide receptor like 1 receptor. Bioconjug Chem. 2008 Dec; 19(12):2401-8.
    View in: PubMed
  37. Oh EJ, Kang SW, Kim BS, Jiang G, Cho IH, Hahn SK. Control of the molecular degradation of hyaluronic acid hydrogels for tissue augmentation. J Biomed Mater Res A. 2008 Sep; 86(3):685-93.
    View in: PubMed
  38. Lee HS, Kim KS, Kim CJ, Hahn SK, Jo MH. Electrical detection of VEGFs for cancer diagnoses using anti-vascular endotherial growth factor aptamer-modified Si nanowire FETs. Biosens Bioelectron. 2009 Feb 15; 24(6):1801-5.
    View in: PubMed
  39. Kim K, Rhee JE, Lee CC, Kim KS, Shin JH, Kwak MJ, Kim JH, Suh GJ, Hahn SK, Singer AJ. Impact of helical computed tomography in clinically evident appendicitis. Emerg Med J. 2008 Aug; 25(8):477-81.
    View in: PubMed
  40. Lee SJ, Kang HW, Park JK, Rhie JW, Hahn SK, Cho DW. Application of microstereolithography in the development of three-dimensional cartilage regeneration scaffolds. Biomed Microdevices. 2008 Apr; 10(2):233-41.
    View in: PubMed
  41. Kim J, Park K, Hahn SK. Effect of hyaluronic acid molecular weight on the morphology of quantum dot-hyaluronic acid conjugates. Int J Biol Macromol. 2008 Jan 1; 42(1):41-5.
    View in: PubMed
  42. Hahn SK, Kim JS, Shimobouji T. Injectable hyaluronic acid microhydrogels for controlled release formulation of erythropoietin. J Biomed Mater Res A. 2007 Mar 15; 80(4):916-24.
    View in: PubMed
  43. Hahn SK, Park JK, Tomimatsu T, Shimoboji T. Synthesis and degradation test of hyaluronic acid hydrogels. Int J Biol Macromol. 2007 Mar 10; 40(4):374-80.
    View in: PubMed
  44. Motokawa K, Hahn SK, Nakamura T, Miyamoto H, Shimoboji T. Selectively crosslinked hyaluronic acid hydrogels for sustained release formulation of erythropoietin. J Biomed Mater Res A. 2006 Sep 1; 78(3):459-65.
    View in: PubMed
  45. Hahn SK, Oh EJ, Miyamoto H, Shimobouji T. Sustained release formulation of erythropoietin using hyaluronic acid hydrogels crosslinked by Michael addition. Int J Pharm. 2006 Sep 28; 322(1-2):44-51.
    View in: PubMed
  46. Hahn SK, Hoffman AS. Preparation and characterization of biocompatible polyelectrolyte complex multilayer of hyaluronic acid and poly-L-lysine. Int J Biol Macromol. 2005 Dec 30; 37(5):227-31.
    View in: PubMed
  47. Kim SJ, Hahn SK, Kim MJ, Kim DH, Lee YP. Development of a novel sustained release formulation of recombinant human growth hormone using sodium hyaluronate microparticles. J Control Release. 2005 May 18; 104(2):323-35.
    View in: PubMed
  48. Ohri R, Hahn SK, Hoffman AS, Stayton PS, Giachelli CM. Hyaluronic acid grafting mitigates calcification of glutaraldehyde-fixed bovine pericardium. J Biomed Mater Res A. 2004 Aug 1; 70(2):328-34.
    View in: PubMed
  49. Hahn SK, Kim SJ, Kim MJ, Kim DH. Characterization and in vivo study of sustained-release formulation of human growth hormone using sodium hyaluronate. Pharm Res. 2004 Aug; 21(8):1374-81.
    View in: PubMed
  50. Hahn SK, Jelacic S, Maier RV, Stayton PS, Hoffman AS. Anti-inflammatory drug delivery from hyaluronic acid hydrogels. J Biomater Sci Polym Ed. 2004; 15(9):1111-9.
    View in: PubMed
  51. Hahn SK, Chang YK, Lee SY. Recovery and characterization of poly(3-hydroxybutyric acid) synthesized in Alcaligenes eutrophus and recombinant Escherichia coli. Appl Environ Microbiol. 1995 Jan; 61(1):34-9.
    View in: PubMed
  52. Hahn SK, Chang YK, Kim BS, Chang HN. Optimization of microbial poly(3-hydroxybutyrate) recover using dispersions of sodium hypochlorite solution and chloroform. Biotechnol Bioeng. 1994 Jun 20; 44(2):256-61.
    View in: PubMed
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