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Last Name
Institution

Jose Alfredo Gomez Puerta, Ph.D., M.D.

TitleResearch Fellow in Medicine (EXT)
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressBrigham and Women's Hospital
Rheum., Immun. & Allergy, Allumnae Hall, Suite 305
41 Av Louis Pasteur
Boston MA 02115
Phone617/264-5906
Fax617/264-3019

 Biography 
 awards and honors
- 2008Emili Letang Ex aequo Fellow of the year

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Fischer S, Agmon-Levin N, Shapira Y, Porat Katz BS, Graell E, Cervera R, Stojanovich L, Gómez Puerta JA, Sanmartí R, Shoenfeld Y. Toxoplasma gondii: bystander or cofactor in rheumatoid arthritis. Immunol Res. 2013 Apr 4.
    View in: PubMed
  2. Merola JF, Prystowsky SD, Iversen C, Gomez-Puerta JA, Norton T, Tsao P, Massarotti E, Schur P, Bermas B, Costenbader KH. Association of discoid lupus erythematosus with other clinical manifestations among patients with systemic lupus erythematosus. J Am Acad Dermatol. 2013 Mar 27.
    View in: PubMed
  3. Gómez-Puerta JA, Peris P, Reverter JC, Espinosa G, Martinez-Ferrer A, Monegal A, Monteagudo J, Tàssies D, Guañabens N. Medicine (Baltimore). High prevalence of pro-thrombotic abnormalities in multifocal osteonecrosis. 2013; In press.
  4. Anaya JM, Castiblanco J, Rojas-Villarraga A, Pineda-Tamayo R, Levy RA, Gómez-Puerta J, Dias C, Mantilla RD, Gallo JE, Cervera R, Shoenfeld Y, Arcos-Burgos M. The multiple autoimmune syndromes. A clue for the autoimmune tautology. Clin Rev Allergy Immunol. 2012 Dec; 43(3):256-64.
    View in: PubMed
  5. Gómez-Puerta JA. Rev Col Reumatol. Environmental factors and rheumatoid arthritis. 2012; 19(4):197-200.
  6. Sanmartí R, Cabrera-Villalba S, Gómez-Puerta JA, Ruiz-Esquide V, Hernández MV, Salvador G, Ramirez J, Viñas O, Cañete JD. Palindromic rheumatism with positive anticitrullinated peptide/protein antibodies is not synonymous with rheumatoid arthritis. A longterm followup study. J Rheumatol. 2012 Oct; 39(10):1929-33.
    View in: PubMed
  7. Espinosa G, Rodríguez-Pintó I, Gomez-Puerta JA, Pons-Estel G, Cervera R. Relapsing catastrophic antiphospholipid syndrome potential role of microangiopathic hemolytic anemia in disease relapses. Semin Arthritis Rheum. 2013 Feb; 42(4):417-23.
    View in: PubMed
  8. Ruiz-Esquide V, Gómara MJ, Peinado VI, Gómez Puerta JA, Barberá JA, Cañete Jde D, Haro I, Sanmartí R. Anti-citrullinated peptide antibodies in the serum of heavy smokers without rheumatoid arthritis. A differential effect of chronic obstructive pulmonary disease? Clin Rheumatol. 2012 Jul; 31(7):1047-50.
    View in: PubMed
  9. Gómez-Puerta JA, Quintana LF, Stone JH, Ramos-Casals M, Bosch X. B-cell depleting agents for ANCA vasculitides: a new therapeutic approach. Autoimmun Rev. 2012 Jul; 11(9):646-52.
    View in: PubMed
  10. Ruiz-Esquide V, Gómez-Puerta JA, Cañete JD, Graell E, Vazquez I, Ercilla MG, Viñas O, Gómez-Centeno A, Haro I, Sanmartí R. Effects of smoking on disease activity and radiographic progression in early rheumatoid arthritis. J Rheumatol. 2011 Dec; 38(12):2536-9.
    View in: PubMed
  11. Malakoutikhah M, Gómara MJ, Gómez-Puerta JA, Sanmartí R, Haro I. The use of chimeric vimentin citrullinated peptides for the diagnosis of rheumatoid arthritis. J Med Chem. 2011 Nov 10; 54(21):7486-92.
    View in: PubMed
  12. Gómez-Puerta JA. Rev Col Reumatol. Gout: New pathogenic concepts and new therapeutic agents. 2011; 3(18):163-174.
  13. Hernández MV, Ruiz-Esquide V, Gómez-Caballero ME, Gómez-Puerta JA, Cañete JD, Sanmartí R. Relapsing polychondritis: a new adverse event secondary to the use of tumour necrosis factor antagonists? Rheumatology (Oxford). 2011 Aug; 50(8):1523-5.
    View in: PubMed
  14. Pons-Estel GJ, Salerni GE, Serrano RM, Gomez-Puerta JA, Plasin MA, Aldasoro E, Lozano M, Cid J, Cervera R, Espinosa G. Therapeutic plasma exchange for the management of refractory systemic autoimmune diseases: report of 31 cases and review of the literature. Autoimmun Rev. 2011 Sep; 10(11):679-84.
    View in: PubMed
  15. Sanmartí R, Gómez-Puerta JA. [Biomarkers in rheumatoid arthritis]. Reumatol Clin. 2011 Mar; 6S3:S25-8.
    View in: PubMed
  16. Gómez-Puerta JA, Bosch X. Therapy: Spleen tyrosine kinase inhibitors--novel therapies for RA? Nat Rev Rheumatol. 2011 Mar; 7(3):134-6.
    View in: PubMed
  17. Haro I, Gómara MJ, Pérez ML, Viñas O, Ercilla G, Gómez-Puerta JA, Sanmartí R. Antibodies against ß-fibrin synthetic peptides: a study of their association with the immunogenetic background and disease course of rheumatoid arthritis patients. Eur J Med Chem. 2011 Apr; 46(4):1095-102.
    View in: PubMed
  18. Engel P, Gómez-Puerta JA, Ramos-Casals M, Lozano F, Bosch X. Therapeutic targeting of B cells for rheumatic autoimmune diseases. Pharmacol Rev. 2011 Mar; 63(1):127-56.
    View in: PubMed
  19. Gifre L, Ruiz-Esquide V, Xaubet A, Gómez-Puerta JA, Hernández MV, Sanmartí R. Lung sarcoidosis induced by TNF antagonists in rheumatoid arthritis: a case presentation and a literature review. Arch Bronconeumol. 2011 Apr; 47(4):208-12.
    View in: PubMed
  20. Gómez-Puerta, J.A, Pons-Estel G. Curr Rheumatol Rev. Skeletal involvement in antiphospholipid syndrome. 2010; (6):25-31.
  21. Gómez-Puerta JA, García-Melchor E. [Young woman with relapsing arthritis]. Reumatol Clin. 2010 Jan-Feb; 6(1):58-62.
    View in: PubMed
  22. Gómez-Puerta JA, Bosch X. Anti-neutrophil cytoplasmic antibody pathogenesis in small-vessel vasculitis: an update. Am J Pathol. 2009 Nov; 175(5):1790-8.
    View in: PubMed
  23. Gómez-Puerta JA, Hernández-Rodríguez J, López-Soto A, Bosch X. Antineutrophil cytoplasmic antibody-associated vasculitides and respiratory disease. Chest. 2009 Oct; 136(4):1101-11.
    View in: PubMed
  24. Sanmartí R, Graell E, Perez ML, Ercilla G, Viñas O, Gómez-Puerta JA, Gratacós J, Balsa A, Gómara MJ, Larrosa M, Cañete JD, Haro I. Diagnostic and prognostic value of antibodies against chimeric fibrin/filaggrin citrullinated synthetic peptides in rheumatoid arthritis. Arthritis Res Ther. 2009; 11(5):R135.
    View in: PubMed
  25. Moll C, Bogas M, Gómez-Puerta JA, Celis R, Vázquez I, Rodríguez F, Kanterewicz E, Sanmarti R, Cañete JD. Macroscopic features of knee synovitis in early untreated Behçet disease and psoriatic arthritis. Clin Rheumatol. 2009 Sep; 28(9):1053-7.
    View in: PubMed
  26. Gómez-Puerta JA, Sanin-Blair J, Galarza-Maldonado C. Pregnancy and catastrophic antiphospholipid syndrome. Clin Rev Allergy Immunol. 2009 Jun; 36(2-3):85-90.
    View in: PubMed
  27. Cervera R, Bucciarelli S, Plasín MA, Gómez-Puerta JA, Plaza J, Pons-Estel G, Shoenfeld Y, Ingelmo M, Espinos G. Catastrophic antiphospholipid syndrome (CAPS): descriptive analysis of a series of 280 patients from the "CAPS Registry". J Autoimmun. 2009 May-Jun; 32(3-4):240-5.
    View in: PubMed
  28. Taverner D, Gómez-Puerta JA. [Dyspnea in a patient with systemic lupus erythematosus]. Reumatol Clin. 2009 Mar-Apr; 5(2):88-91.
    View in: PubMed
  29. Graell E, Vazquez I, Larrosa M, Rodríguez-Cros JR, Hernández MV, Gratacós J, Gómez A, Cañete JD, Gómez-Puerta JA, Sanmartí R. Disability measured by the modified health assessment questionnaire in early rheumatoid arthritis: prognostic factors after two years of follow-up. Clin Exp Rheumatol. 2009 Mar-Apr; 27(2):284-91.
    View in: PubMed
  30. Cañete JD, Celis R, Noordenbos T, Moll C, Gómez-Puerta JA, Pizcueta P, Palacin A, Tak PP, Sanmartí R, Baeten D. Distinct synovial immunopathology in Behçet disease and psoriatic arthritis. Arthritis Res Ther. 2009; 11(1):R17.
    View in: PubMed
  31. Gómez-Puerta JA, Espinosa G, Morlà R, Cid MC, Cervera R. Interstitial lung disease as a presenting manifestation of microscopic polyangiitis successfully treated with mycophenolate mofetil. Clin Exp Rheumatol. 2009 Jan-Feb; 27(1):166-7.
    View in: PubMed
  32. Gómez-Puerta JA, Cervera R, Moll C, Solé M, Collado A, Sanmartí R. Proliferative lupus nephritis in a patient with systemic lupus erythematosus and longstanding secondary amyloid nephropathy. Clin Rheumatol. 2009 Jan; 28(1):95-7.
    View in: PubMed
  33. Gómez-Puerta JA, Burlingame RW, Cervera R. Anti-chromatin (anti-nucleosome) antibodies: diagnostic and clinical value. Autoimmun Rev. 2008 Sep; 7(8):606-11.
    View in: PubMed
  34. Gómez-Puerta, J.A, Cervera R. Medicina & Laboratorio. Systemic lupus erythematosus. 2008; (14):301-13.
  35. Sanmartí, R, Hernandez MV, Gómez Puerta JA, Graell E, Cañete JD. Int J Adv Rheumatol. Serum autoantibodies in Rheumatoid Arthritis. 2008; (6):47-52.
  36. Moll C, Hernández MV, Cañete JD, Gómez-Puerta JA, Soriano A, Collado A, Sanmartí R. Ilium osteitis as the main manifestation of the SAPHO syndrome: response to infliximab therapy and review of the literature. Semin Arthritis Rheum. 2008 Apr; 37(5):299-306.
    View in: PubMed
  37. Gómez-Puerta JA, Peris P, Llusá M, Guañabens N. Sacral stress fracture as a cause of gluteal artery injury: an unusual complication of a common fracture. Joint Bone Spine. 2008 Mar; 75(2):239-41.
    View in: PubMed
  38. Asherson RA, Spargo C, Gómez-Puerta JA. Partial HELLP syndrome in pregnancy complicated by recurrent deep vein thromboses and palmar skin lesions in a patient with prothrombin gene 20210a mutation and antiphospholipid antibodies: an unusual case. Clin Rheumatol. 2008 Feb; 27(2):245-8.
    View in: PubMed
  39. Cervera R, Bucciarelli S, Espinosa G, Gómez-Puerta JA, Ramos-Casals M, Shoenfeld Y, Piette JC, Asherson RA. Catastrophic antiphospholipid syndrome: lessons from the "CAPS Registry"--a tribute to the late Josep Font. Ann N Y Acad Sci. 2007 Jun; 1108:448-56.
    View in: PubMed
  40. Miesbach W, Asherson RA, Cervera R, Shoenfeld Y, Gomez Puerta J, Espinosa G, Bucciarelli S. The role of malignancies in patients with catastrophic anti-phospholipid (Asherson's) syndrome. Clin Rheumatol. 2007 Dec; 26(12):2109-14.
    View in: PubMed
  41. Gómez-Puerta JA, Cervera R, Espinosa G, Asherson RA, García-Carrasco M, da Costa IP, Andrade DC, Borba EF, Makatsaria A, Bucciarelli S, Ramos-Casals M, Font J. Catastrophic antiphospholipid syndrome during pregnancy and puerperium: maternal and fetal characteristics of 15 cases. Ann Rheum Dis. 2007 Jun; 66(6):740-6.
    View in: PubMed
  42. García-Carrasco M, Galarza C, Gómez-Ponce M, Cervera R, Rojas-Rodríguez J, Espinosa G, Bucciarelli S, Gómez-Puerta JA, Bové A, Escárcega RO, Font J. Antiphospholipid syndrome in Latin American patients: clinical and immunologic characteristics and comparison with European patients. Lupus. 2007; 16(5):366-73.
    View in: PubMed
  43. Gómez-Puerta, J.A, Peris P, Guañabens N. Semin Fund Esp Reumatol. Multiple osteonecrosis. Pathogenic mechanisms, clinical characteristics and treatment. 2007; (8):185-92.
  44. Sanmartí R, Gómez-Centeno A, Ercilla G, Larrosa M, Viñas O, Vazquez I, Gómez-Puerta JA, Gratacós J, Salvador G, Cañete JD. Prognostic factors of radiographic progression in early rheumatoid arthritis: a two year prospective study after a structured therapeutic strategy using DMARDs and very low doses of glucocorticoids. Clin Rheumatol. 2007 Jul; 26(7):1111-8.
    View in: PubMed
  45. Bucciarelli S, Espinosa G, Cervera R, Erkan D, Gómez-Puerta JA, Ramos-Casals M, Font J, Asherson RA. Mortality in the catastrophic antiphospholipid syndrome: causes of death and prognostic factors in a series of 250 patients. Arthritis Rheum. 2006 Aug; 54(8):2568-76.
    View in: PubMed
  46. Miesbach W, Asherson RA, Cervera R, Shoenfeld Y, Gomez Puerta J, Bucciarelli S, Espinoza G, Font J. The catastrophic antiphospholipid (Asherson's) syndrome and malignancies. Autoimmun Rev. 2006 Dec; 6(2):94-7.
    View in: PubMed
  47. Cervera R, Espinosa G, Bucciarelli S, Gómez-Puerta JA, Font J. Lessons from the catastrophic antiphospholipid syndrome (CAPS) registry. Autoimmun Rev. 2006 Dec; 6(2):81-4.
    View in: PubMed
  48. Bucciarelli S, Cervera R, Espinosa G, Gómez-Puerta JA, Ramos-Casals M, Font J. Mortality in the catastrophic antiphospholipid syndrome: causes of death and prognostic factors. Autoimmun Rev. 2006 Dec; 6(2):72-5.
    View in: PubMed
  49. Gómez-Puerta JA, Cervera R, Espinosa G, Bucciarelli S, Font J. Pregnancy and puerperium are high susceptibility periods for the development of catastrophic antiphospholipid syndrome. Autoimmun Rev. 2006 Dec; 6(2):85-8.
    View in: PubMed
  50. Espinosa G, Bucciarelli S, Cervera R, Gómez-Puerta JA, Font J. Laboratory studies on pathophysiology of the catastrophic antiphospholipid syndrome. Autoimmun Rev. 2006 Dec; 6(2):68-71.
    View in: PubMed
  51. Gómez-Puerta JA, Espinosa G, Miró JM, Sued O, Llibre JM, Cervera R, Font J. Behçet's disease in an HIV-1-infected patient treated with highly active antiretroviral therapy. Isr Med Assoc J. 2006 Jul; 8(7):513-4.
    View in: PubMed
  52. Escobar MC, Gómez-Puerta JA, Albert D, Ferrer Q, Girona J. Recurrent congenital heart block in neonatal lupus. Clin Rheumatol. 2007 Jul; 26(7):1161-3.
    View in: PubMed
  53. Gómez-Puerta JA, Cervera R, Espinosa G, Aguiló S, Bucciarelli S, Ramos-Casals M, Ingelmo M, Asherson RA, Font J. Antiphospholipid antibodies associated with malignancies: clinical and pathological characteristics of 120 patients. Semin Arthritis Rheum. 2006 Apr; 35(5):322-32.
    View in: PubMed
  54. Gómez-Puerta JA, Peris P, Grau JM, Martinez MA, Guañabens N. Camptocormia as a clinical manifestation of mitochondrial myopathy. Clin Rheumatol. 2007 Jun; 26(6):1017-9.
    View in: PubMed
  55. Gomez-Puerta JA, Salgado E, Cervera R, Aguilo S, Ramos-Casals M, Soler M, Torras A, Font J. Catastrophic antiphospholipid syndrome presenting with renal thrombotic microangiopathy and diffuse proliferative glomerulonephritis. Clin Exp Rheumatol. 2006 Jan-Feb; 24(1):110.
    View in: PubMed
  56. Gómez-Puerta, J.A, Font J. Inmunológica. Lupus nephritis. Update in classification and treatment. 2006; 2:5-13.
  57. Gómez-Puerta JA, Burlingame RW, Cervera R. Anti-chromatin (anti-nucleosome) antibodies. Lupus. 2006; 15(7):408-11.
    View in: PubMed
  58. Rees JD, Lança S, Marques PV, Gómez-Puerta JA, Moco R, Oliveri C, Khamashta MA, Hughes GR, D'Cruz DP. Prevalence of the antiphospholipid syndrome in primary systemic vasculitis. Ann Rheum Dis. 2006 Jan; 65(1):109-11.
    View in: PubMed
  59. Gómez-Puerta JA, Musuruana J, Saez C, Cervera R, Font J. [Sarcoidosis as seronegative spondyloarthropathy]. Biomedica. 2005 Dec; 25(4):435-8.
    View in: PubMed
  60. Asherson RA, Gómez-Puerta JA, Marinopoulos G. Recurrent pulmonary thromboembolism in a patient with systemic lupus erythematosus and HIV-1 infection associated with the presence of antibodies to prothrombin: a case report. Clin Infect Dis. 2005 Nov 15; 41(10):e89-92.
    View in: PubMed
  61. Gómez-Puerta JA, Martín H, Amigo MC, Aguirre MA, Camps MT, Cuadrado MJ, Hughes GR, Khamashta MA. Long-term follow-up in 128 patients with primary antiphospholipid syndrome: do they develop lupus? Medicine (Baltimore). 2005 Jul; 84(4):225-30.
    View in: PubMed
  62. Asherson RA, Espinosa G, Cervera R, Gómez-Puerta JA, Musuruana J, Bucciarelli S, Ramos-Casals M, Martínez-González AL, Ingelmo M, Reverter JC, Font J, Triplett DA. Disseminated intravascular coagulation in catastrophic antiphospholipid syndrome: clinical and haematological characteristics of 23 patients. Ann Rheum Dis. 2005 Jun; 64(6):943-6.
    View in: PubMed
  63. Bucciarelli S, Espinosa G, Asherson RA, Cervera R, Claver G, Gómez-Puerta JA, Ramos-Casals M, Ingelmo M. The acute respiratory distress syndrome in catastrophic antiphospholipid syndrome: analysis of a series of 47 patients. Ann Rheum Dis. 2006 Jan; 65(1):81-6.
    View in: PubMed
  64. Cervera R, Font J, Gómez-Puerta JA, Espinosa G, Cucho M, Bucciarelli S, Ramos-Casals M, Ingelmo M, Piette JC, Shoenfeld Y, Asherson RA. Validation of the preliminary criteria for the classification of catastrophic antiphospholipid syndrome. Ann Rheum Dis. 2005 Aug; 64(8):1205-9.
    View in: PubMed
  65. Gómez-Puerta, J.A, Pomes J, Sanmartí R. Human Brucellosis. Clinical manifestations emphasizing ostearticular manifestation. 2005; (6):93-102.
  66. Gómez-Puerta, J.A, Sanmartí R. Avances en Reumatología. Rheumatoid arthritis and cardiovascular disease. 2005; 7-18.
  67. Rivero MG, Salvatore AJ, Gómez-Puerta JA, Mascaró JM, Cañete JD, Muñoz-Gómez J, Sanmartí R. Accelerated nodulosis during methotrexate therapy in a patient with systemic lupus erythematosus and Jaccoud's arthropathy. Rheumatology (Oxford). 2004 Dec; 43(12):1587-8.
    View in: PubMed
  68. Cervera R, Asherson RA, Acevedo ML, Gómez-Puerta JA, Espinosa G, De La Red G, Gil V, Ramos-Casals M, García-Carrasco M, Ingelmo M, Font J. Antiphospholipid syndrome associated with infections: clinical and microbiological characteristics of 100 patients. Ann Rheum Dis. 2004 Oct; 63(10):1312-7.
    View in: PubMed
  69. Gómez-Puerta JA, Cervera R, Calvo LM, Gómez-Ansón B, Espinosa G, Claver G, Bucciarelli S, Bové A, Ramos-Casals M, Ingelmo M, Font J. Dementia associated with the antiphospholipid syndrome: clinical and radiological characteristics of 30 patients. Rheumatology (Oxford). 2005 Jan; 44(1):95-9.
    View in: PubMed
  70. Gómez-Puerta JA, Sanmartí R, Rodríguez-Cros JR, Cañete JD. Etanercept is effective in patients with rheumatoid arthritis with no response to infliximab therapy. Ann Rheum Dis. 2004 Jul; 63(7):896.
    View in: PubMed
  71. Sanmartí R, Gómez-Puerta JA, Rodríguez-Cros JR, Albaladejo C, Muñoz-Gómez J, Cañete JD. [Etanercept in rheumatoid arthritis patients with a poor therapeutic response to infliximab]. Med Clin (Barc). 2004 Mar 13; 122(9):321-4.
    View in: PubMed
  72. Gómez-Puerta JA, Gil V, Cervera R, Miquel R, Jiménez S, Ramos-Casals M, Font J. Coeliac disease associated with systemic sclerosis. Ann Rheum Dis. 2004 Jan; 63(1):104-5.
    View in: PubMed
  73. Gómez-Puerta JA, Cucho Venegas M, Cervera Segura R, Font Franco J. [Intravenous immunoglobulins in the systemic autoinmune diseases]. Rev Clin Esp. 2003 Nov; 203(11):548-54.
    View in: PubMed
  74. Gómez-Puerta JA, Gil V, Cervera R. "Catastrophic" antiphospholipid syndrome. Mayo Clin Proc. 2003 Apr; 78(4):519; author reply 519, 521.
    View in: PubMed
  75. Gómez-Puerta JA, Cervera R, Khamashta MA. Acta Med Col. Twenty years of the antiphospholipid syndrome. Past, present and future. 2003; 28:61- 62.
  76. Gómez-Puerta JA, Levy S, Khamashta MA, Hughes GR. Periorbital oedema in systemic lupus erythematosus. Lupus. 2003; 12(11):866-9.
    View in: PubMed
  77. Gómez-Puerta, J.A, Molina JF, López F. Rev Col Reumatol. Cardiac manifestations of rheumatic diseases. 2002; (9):203-13.
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