 Seung-Joo Lee, PH.D.
| Title | Research Associate in Biological Chemistry and Molecular Pharmacology |
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| Institution | Harvard Medical School |
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| Department | Biological Chemistry & Molecular Pharmacology |
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| Address | Harvard Medical School
Bcmp C2-223
240 Longwood Ave
Boston MA 02115
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| Phone | 617/432-3130 |
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| Fax | 617/432-3362 |
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 Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Zhang H, Lee SJ, Richardson CC. Essential protein interactions within the replisome regulate DNA replication. Cell Cycle. 2011 Oct 15; 10(20):3413-4.
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Lee SJ, Richardson CC. Choreography of bacteriophage T7 DNA replication. Curr Opin Chem Biol. 2011 Oct; 15(5):580-6.
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Zhu B, Lee SJ, Richardson CC. Bypass of a nick by the replisome of bacteriophage T7. J Biol Chem. 2011 Aug 12; 286(32):28488-97.
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Zhang H, Lee SJ, Zhu B, Tran NQ, Tabor S, Richardson CC. Helicase-DNA polymerase interaction is critical to initiate leading-strand DNA synthesis. Proc Natl Acad Sci U S A. 2011 Jun 7; 108(23):9372-7.
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Akabayov B, Akabayov SR, Lee SJ, Tabor S, Kulczyk AW, Richardson CC. Conformational dynamics of bacteriophage T7 DNA polymerase and its processivity factor, Escherichia coli thioredoxin. Proc Natl Acad Sci U S A. 2010 Aug 24; 107(34):15033-8.
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Lee SJ, Richardson CC. Molecular basis for recognition of nucleoside triphosphate by gene 4 helicase of bacteriophage T7. J Biol Chem. 2010 Oct 8; 285(41):31462-71.
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Tran NQ, Lee SJ, Richardson CC, Tabor S. A novel nucleotide kinase encoded by gene 1.7 of bacteriophage T7. Mol Microbiol. 2010 Jul; 77(2):492-504.
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Zhu B, Lee SJ, Richardson CC. Direct role for the RNA polymerase domain of T7 primase in primer delivery. Proc Natl Acad Sci U S A. 2010 May 18; 107(20):9099-104.
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Lee SJ, Zhu B, Hamdan SM, Richardson CC. Mechanism of sequence-specific template binding by the DNA primase of bacteriophage T7. Nucleic Acids Res. 2010 Jul; 38(13):4372-83.
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Zhu B, Lee SJ, Richardson CC. An in trans interaction at the interface of the helicase and primase domains of the hexameric gene 4 protein of bacteriophage T7 modulates their activities. J Biol Chem. 2009 Aug 28; 284(35):23842-51.
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Lee SJ, Chowdhury K, Tabor S, Richardson CC. Rescue of bacteriophage T7 DNA polymerase of low processivity by suppressor mutations affecting gene 3 endonuclease. J Virol. 2009 Sep; 83(17):8418-27.
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Akabayov B, Lee SJ, Akabayov SR, Rekhi S, Zhu B, Richardson CC. DNA recognition by the DNA primase of bacteriophage T7: a structure-function study of the zinc-binding domain. Biochemistry. 2009 Mar 3; 48(8):1763-73.
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Lee SJ, Qimron U, Richardson CC. Communication between subunits critical to DNA binding by hexameric helicase of bacteriophage T7. Proc Natl Acad Sci U S A. 2008 Jul 1; 105(26):8908-13.
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Johnson DE, Takahashi M, Hamdan SM, Lee SJ, Richardson CC. Exchange of DNA polymerases at the replication fork of bacteriophage T7. Proc Natl Acad Sci U S A. 2007 Mar 27; 104(13):5312-7.
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Lee SJ, Marintcheva B, Hamdan SM, Richardson CC. The C-terminal residues of bacteriophage T7 gene 4 helicase-primase coordinate helicase and DNA polymerase activities. J Biol Chem. 2006 Sep 1; 281(35):25841-9.
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Marintcheva B, Hamdan SM, Lee SJ, Richardson CC. Essential residues in the C terminus of the bacteriophage T7 gene 2.5 single-stranded DNA-binding protein. J Biol Chem. 2006 Sep 1; 281(35):25831-40.
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Qimron U, Lee SJ, Hamdan SM, Richardson CC. Primer initiation and extension by T7 DNA primase. EMBO J. 2006 May 17; 25(10):2199-208.
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Lee SJ, Richardson CC. Acidic residues in the nucleotide-binding site of the bacteriophage T7 DNA primase. J Biol Chem. 2005 Jul 22; 280(29):26984-91.
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Hamdan SM, Marintcheva B, Cook T, Lee SJ, Tabor S, Richardson CC. A unique loop in T7 DNA polymerase mediates the binding of helicase-primase, DNA binding protein, and processivity factor. Proc Natl Acad Sci U S A. 2005 Apr 5; 102(14):5096-101.
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Lee SJ, Richardson CC. The linker region between the helicase and primase domains of the gene 4 protein of bacteriophage T7. Role in helicase conformation and activity. J Biol Chem. 2004 May 28; 279(22):23384-93.
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Lee SJ, Richardson CC. Interaction of adjacent primase domains within the hexameric gene 4 helicase-primase of bacteriophage T7. Proc Natl Acad Sci U S A. 2002 Oct 1; 99(20):12703-8.
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Lee SJ, Richardson CC. Essential lysine residues in the RNA polymerase domain of the gene 4 primase-helicase of bacteriophage T7. J Biol Chem. 2001 Dec 28; 276(52):49419-26.
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